CAS 131802-60-3 | Quinoline, 7-(phenylmethoxy)- | CAS Number 131802-60-3

200,000+ products from a single source!

sales@angenechem.com

Product Categories

Home > Quinoline > 131802-60-3

131802-60-3 | Quinoline, 7-(phenylmethoxy)-

CAS No: 131802-60-3 Catalog No: AG000ZRN MDL No:

Product Description

Catalog Number:

AG000ZRN

Chemical Name:

Quinoline, 7-(phenylmethoxy)-

CAS Number:

131802-60-3

Molecular Formula:

C16H13NO

Molecular Weight:

235.2805

IUPAC Name:

7-phenylmethoxyquinoline

InChI:

InChI=1S/C16H13NO/c1-2-5-13(6-3-1)12-18-15-9-8-14-7-4-10-17-16(14)11-15/h1-11H,12H2

InChI Key:

SIDLHXXVIBTSJZ-UHFFFAOYSA-N

SMILES:

c1ccc(cc1)COc1ccc2c(c1)nccc2

Properties

Complexity:

250

Compound Is Canonicalized:

Yes

Covalently-Bonded Unit Count:

Defined Atom Stereocenter Count:

Defined Bond Stereocenter Count:

Exact Mass:

235.1g/mol

Formal Charge:

Heavy Atom Count:

Hydrogen Bond Acceptor Count:

Hydrogen Bond Donor Count:

Isotope Atom Count:

Molecular Weight:

235.286g/mol

Monoisotopic Mass:

235.1g/mol

Rotatable Bond Count:

Topological Polar Surface Area:

22.1A^2

Undefined Atom Stereocenter Count:

Undefined Bond Stereocenter Count:

XLogP3:

3.9

Literature

Title	Journal
Improvac does not modify the expression and activities of the major drug metabolizing enzymes cytochrome P450 3A and 2C in pigs.	Vaccine 20120521
Comparison of three fluorescent CYP3A substrates in two vertebrate models: pig and Atlantic salmon.	Animal : an international journal of animal bioscience 20120401
Exploration of the amine terminus in a novel series of 1,2,4-triazolo-3-yl-azabicyclo[3.1.0]hexanes as selective dopamine D3 receptor antagonists.	Journal of medicinal chemistry 20101014
Computational approach to characterization of human liver drug-metabolizing enzymes.	European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20101009
Assessment of cytochrome P450 fluorometric substrates with rainbow trout and killifish exposed to dexamethasone, pregnenolone-16alpha-carbonitrile, rifampicin, and beta-naphthoflavone.	Aquatic toxicology (Amsterdam, Netherlands) 20100510
Effects of cytochrome P450 inhibitors on the biotransformation of fluorogenic substrates by adult male rat liver microsomes and cDNA-expressed rat cytochrome P450 isoforms.	Toxicological sciences : an official journal of the Society of Toxicology 20100201
1,2,4-Triazolyl azabicyclo[3.1.0]hexanes: a new series of potent and selective dopamine D(3) receptor antagonists.	Journal of medicinal chemistry 20100114
DP7, a novel dihydropyridine multidrug resistance reverter, shows only weak inhibitory activity on human CYP3A enzyme(s).	European journal of pharmacology 20090701
Ligand diversity of human and chimpanzee CYP3A4: activation of human CYP3A4 by lithocholic acid results from positive selection.	Drug metabolism and disposition: the biological fate of chemicals 20090601
In vitro CYP3A4 metabolism: inhibition by Echinacea purpurea and choice of substrate for the evaluation of herbal inhibition.	Basic & clinical pharmacology & toxicology 20081101
Multiple substrate binding by cytochrome P450 3A4: estimation of the number of bound substrate molecules.	Drug metabolism and disposition: the biological fate of chemicals 20081001
Effect of glutathione on homo- and heterotropic cooperativity in cytochrome P450 3A4.	Archives of biochemistry and biophysics 20080315
Structure-activity relationship and substrate-dependent phenomena in effects of ginsenosides on activities of drug-metabolizing P450 enzymes.	PloS one 20080101
Time-dependent inactivation of P450 3A4 by raloxifene: identification of Cys239 as the site of apoprotein alkylation.	Chemical research in toxicology 20070601
Engineering of cytochrome P450 3A4 for enhanced peroxide-mediated substrate oxidation using directed evolution and site-directed mutagenesis.	Drug metabolism and disposition: the biological fate of chemicals 20061201
Time-resolved fluorescence studies of heterotropic ligand binding to cytochrome P450 3A4.	Biochemistry 20061010
CYP3A4 activity in four different animal species liver microsomes using 7-benzyloxyquinoline and HPLC/spectrofluorometric determination.	Journal of pharmaceutical and biomedical analysis 20060123
Cytochrome P450 3A expression and activity in the rabbit lacrimal gland: glucocorticoid modulation and the impact on androgen metabolism.	Investigative ophthalmology & visual science 20051201
Role of cytochrome B5 in modulating peroxide-supported cyp3a4 activity: evidence for a conformational transition and cytochrome P450 heterogeneity.	Drug metabolism and disposition: the biological fate of chemicals 20050801
Cytochrome P450 3A4-catalyzed testosterone 6beta-hydroxylation stereochemistry, kinetic deuterium isotope effects, and rate-limiting steps.	The Journal of biological chemistry 20050520
Suppression of drug-metabolizing enzymes and efflux transporters in the intestine of endotoxin-treated rats.	Drug metabolism and disposition: the biological fate of chemicals 20040101
High-throughput screening for the assessment of time-dependent inhibitions of new drug candidates on recombinant CYP2D6 and CYP3A4 using a single concentration method.	Xenobiotica; the fate of foreign compounds in biological systems 20040101
Homotropic versus heterotopic cooperativity of cytochrome P450eryF: a substrate oxidation and spectral titration study.	Drug metabolism and disposition: the biological fate of chemicals 20030401
Cytochrome P450 fluorometric substrates: identification of isoform-selective probes for rat CYP2D2 and human CYP3A4.	Drug metabolism and disposition: the biological fate of chemicals 20020701
7-Benzyloxyquinoline oxidation by P450eryF A245T: finding of a new fluorescent substrate probe.	Chemical research in toxicology 20020601
Site-directed mutagenesis of cytochrome P450eryF: implications for substrate oxidation, cooperativity, and topology of the active site.	Chemical research in toxicology 20020601
Evaluation of 7-benzyloxy-4-trifluoromethylcoumarin, some other 7-hydroxy-4-trifluoromethylcoumarin derivatives and 7-benzyloxyquinoline as fluorescent substrates for rat hepatic cytochrome P450 enzymes.	Xenobiotica; the fate of foreign compounds in biological systems 20011201
Testosterone, 7-benzyloxyquinoline, and 7-benzyloxy-4-trifluoromethyl-coumarin bind to different domains within the active site of cytochrome P450 3A4.	Drug metabolism and disposition: the biological fate of chemicals 20011101
Metabolism of 2,5-bis(trifluoromethyl)-7-benzyloxy-4-trifluoromethylcoumarin by human hepatic CYP isoforms: evidence for selectivity towards CYP3A4.	Xenobiotica; the fate of foreign compounds in biological systems 20010401