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13073-21-7

13073-21-7 | L-Homocysteine, S-butyl-

CAS No: 13073-21-7 Catalog No: AG000UVR MDL No:

Product Description

Catalog Number:
AG000UVR
Chemical Name:
L-Homocysteine, S-butyl-
CAS Number:
13073-21-7
Molecular Formula:
C8H17NO2S
Molecular Weight:
191.2911
IUPAC Name:
(2S)-2-amino-4-butylsulfanylbutanoic acid
InChI:
InChI=1S/C8H17NO2S/c1-2-3-5-12-6-4-7(9)8(10)11/h7H,2-6,9H2,1H3,(H,10,11)/t7-/m0/s1
InChI Key:
LAXXPOJCFVMVAX-ZETCQYMHSA-N
SMILES:
CCCCSCC[C@@H](C(=O)O)N

Properties

Complexity:
130  
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
1  
Defined Bond Stereocenter Count:
0
Exact Mass:
191.098g/mol
Formal Charge:
0
Heavy Atom Count:
12  
Hydrogen Bond Acceptor Count:
4  
Hydrogen Bond Donor Count:
2  
Isotope Atom Count:
0
Molecular Weight:
191.289g/mol
Monoisotopic Mass:
191.098g/mol
Rotatable Bond Count:
7  
Topological Polar Surface Area:
88.6A^2
Undefined Atom Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
XLogP3:
-0.6  

Literature

Title Journal
Impact of terminal dimethylation on the resistance profile of α-N-heterocyclic thiosemicarbazones. Biochemical pharmacology 20120615
Topical hypopigmenting agents for pigmentary disorders and their mechanisms of action. Annals of dermatology 20120201
Protein carbonylation and aggregation precede neuronal apoptosis induced by partial glutathione depletion. ASN neuro 20120101
Glutathione is a key player in metal-induced oxidative stress defenses. International journal of molecular sciences 20120101
The ascorbate-glutathione-α-tocopherol triad in abiotic stress response. International journal of molecular sciences 20120101
Enhancement of gallic acid-induced human pulmonary fibroblast cell death by N-acetyl cysteine and L-buthionine sulfoximine. Human & experimental toxicology 20110801
Bufalin Induces Reactive Oxygen Species Dependent Bax Translocation and Apoptosis in ASTC-a-1 Cells. Evidence-based complementary and alternative medicine : eCAM 20110101
Transient alteration of cellular redox buffering before irradiation triggers apoptosis in head and neck carcinoma stem and non-stem cells. PloS one 20110101
Kallikreins 5, 6 and 10 differentially alter pathophysiology and overall survival in an ovarian cancer xenograft model. PloS one 20110101
Acceleration of the meckel syndrome by near-infrared light therapy. Nephron extra 20110101
Differential effect of covalent protein modification and glutathione depletion on the transcriptional response of Nrf2 and NF-kappaB. Biochemical pharmacology 20100801
Chelation in metal intoxication. International journal of environmental research and public health 20100701
Effect of paraquat-induced oxidative stress on insulin regulation of insulin-like growth factor-binding protein-1 gene expression. Journal of clinical biochemistry and nutrition 20100301
Alterations in lenticular proteins during ageing and selenite-induced cataractogenesis in Wistar rats. Molecular vision 20100101
Glutathione deficiency down-regulates hepatic lipogenesis in rats. Lipids in health and disease 20100101
Drug resistance in leishmaniasis. Journal of global infectious diseases 20100101
Anti-cancer effect of HIV-1 viral protein R on doxorubicin resistant neuroblastoma. PloS one 20100101
Use of sulodexide in patients with peripheral vascular disease. Journal of blood medicine 20100101
Hepatoprotective Activity of Licorice Water Extract against Cadmium-induced Toxicity in Rats. Evidence-based complementary and alternative medicine : eCAM 20090601
Intestinal barrier function in response to abundant or depleted mucosal glutathione in Salmonella-infected rats. BMC physiology 20090101
Evaluation of lenticular antioxidant and redox system components in the lenses of acetyl-L-carnitine treatment in BSO-induced glutathione deprivation. Molecular vision 20090101
Dynamic telomerase gene suppression via network effects of GSK3 inhibition. PloS one 20090101
Inhibition of glutathione and thioredoxin metabolism enhances sensitivity to perifosine in head and neck cancer cells. Journal of oncology 20090101
Growth inhibition of re-challenge B16 melanoma transplant by conjugates of melanogenesis substrate and magnetite nanoparticles as the basis for developing melanoma-targeted chemo-thermo-immunotherapy. Journal of biomedicine & biotechnology 20090101
Effect of COPD treatments on MRP1-mediated transport in bronchial epithelial cells. International journal of chronic obstructive pulmonary disease 20080901
Cytoprotective Activity of Glycyrrhizae radix Extract Against Arsenite-induced Cytotoxicity. Evidence-based complementary and alternative medicine : eCAM 20080601
Effects of N-acetylcysteine and glutathione ethyl ester drops on streptozotocin-induced diabetic cataract in rats. Molecular vision 20080101
A polyadenylation factor subunit implicated in regulating oxidative signaling in Arabidopsis thaliana. PloS one 20080101
Buthionine sulfoximine sensitizes antihormone-resistant human breast cancer cells to estrogen-induced apoptosis. Breast cancer research : BCR 20080101
Involvement of glutathione in puberty and FSH release. Neuroscience letters 20070809
Effect of various radical generators on insulin-dependent regulation of hepatic gene expression. Bioscience, biotechnology, and biochemistry 20070101
Visualization of three-way comparisons of omics data. BMC bioinformatics 20070101
Increased glutathione biosynthesis by Nrf2 activation in astrocytes prevents p75NTR-dependent motor neuron apoptosis. Journal of neurochemistry 20060501
Phytochelatin plays a role in UV-B tolerance in N2-fixing cyanobacterium Anabaena doliolum. Journal of plant physiology 20051101
Ischemia-reperfusion injury of adipofascial tissue: an experimental study evaluating early histologic and biochemical alterations in rats. Mediators of inflammation 20051024
Multidrug resistance-associated protein 1 (MRP1) mediated vincristine resistance: effects of N-acetylcysteine and Buthionine sulfoximine. Cancer cell international 20050101
Vitamin E prevents buthionine sulfoximine-induced biochemical disorders in the rat. The Journal of pharmacy and pharmacology 20040101
Molecular basis of vitamin E action: tocotrienol modulates 12-lipoxygenase, a key mediator of glutamate-induced neurodegeneration. The Journal of biological chemistry 20031031
Radiosensitivity in multidrug-resistant and cisplatin-resistant human carcinoma cell lines. American journal of clinical oncology 20030801
Effect of glutathione depletion and hydrophilic bile acids on hepatic acute phase reaction in rats with extrahepatic cholestasis. Scandinavian journal of gastroenterology 20030801
Role of gamma-glutamyltranspeptidase on the response of poorly and moderately differentiated rhabdomyosarcoma cell lines to buthionine sulfoximine-induced inhibition of glutathione synthesis. Anti-cancer drugs 20020301
Auto-protective redox buffering systems in stimulated macrophages. BMC immunology 20020101
Amine oxidase, spermine, and hyperthermia induce cytotoxicity in P-glycoprotein overexpressing multidrug resistant Chinese hamster ovary cells. Biochemistry and cell biology = Biochimie et biologie cellulaire 20010101

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