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130497-33-5 | Ethanone, 2-(3,4-dichlorophenyl)-1-[2-(1-pyrrolidinylmethyl)-1-piperidinyl]-
CAS No: 130497-33-5 Catalog No: AG000UI6 MDL No:MFCD00672679
Product Description
Catalog Number:
AG000UI6
Chemical Name:
Ethanone, 2-(3,4-dichlorophenyl)-1-[2-(1-pyrrolidinylmethyl)-1-piperidinyl]-
CAS Number:
130497-33-5
Molecular Formula:
C18H24Cl2N2O
Molecular Weight:
355.3020
MDL Number:
MFCD00672679
IUPAC Name:
2-(3,4-dichlorophenyl)-1-[2-(pyrrolidin-1-ylmethyl)piperidin-1-yl]ethanone;hydrochloride
InChI:
InChI=1S/C18H24Cl2N2O.ClH/c19-16-7-6-14(11-17(16)20)12-18(23)22-10-2-1-5-15(22)13-21-8-3-4-9-21;/h6-7,11,15H,1-5,8-10,12-13H2;1H
InChI Key:
NGVLSOWJSUUYDE-UHFFFAOYSA-N
SMILES:
O=C(N1CCCCC1CN1CCCC1)Cc1ccc(c(c1)Cl)Cl
Properties
Complexity:
401
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
2
Defined Atom Stereocenter Count:
0
Defined Bond Stereocenter Count:
0
Exact Mass:
390.103g/mol
Formal Charge:
0
Heavy Atom Count:
24
Hydrogen Bond Acceptor Count:
2
Hydrogen Bond Donor Count:
1
Isotope Atom Count:
0
Molecular Weight:
391.761g/mol
Monoisotopic Mass:
390.103g/mol
Rotatable Bond Count:
4
Topological Polar Surface Area:
23.6A^2
Undefined Atom Stereocenter Count:
1
Undefined Bond Stereocenter Count:
0
Literature
| Title | Journal |
|---|---|
| Genetic mapping of targets mediating differential chemical phenotypes in Plasmodium falciparum. | Nature chemical biology 20091001 |
| The effect of kappa-opioid receptor agonists on tetrodotoxin-resistant sodium channels in primary sensory neurons. | Anesthesia and analgesia 20090801 |
| Presynaptic opioid and nicotinic receptor modulation of dopamine overflow in the nucleus accumbens. | The Journal of neuroscience : the official journal of the Society for Neuroscience 20080213 |
| Cardioprotective and antiarrhythmic effect of U50,488H in ischemia/reperfusion rat heart. | Heart and vessels 20070901 |
| Ischemic neuroprotection with selective kappa-opioid receptor agonist is gender specific. | Stroke 20050701 |
| Prolonged opportunity for ischemic neuroprotection with selective kappa-opioid receptor agonist in rats. | Stroke 20040501 |
| Neuroprotective kappa-opioid receptor agonist BRL 52537 attenuates ischemia-evoked nitric oxide production in vivo in rats. | Stroke 20030601 |
| Inhibition of cAMP accumulation by kappa-receptor activation in isolated iris-ciliary bodies: role of phosphodiesterase and protein kinase C. | The Journal of pharmacology and experimental therapeutics 20020501 |
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