200,000+ products from a single source!
sales@angenechem.com
129203-60-7 | L-Glutamine, 5-oxo-L-prolyl-L-phenylalanyl-L-threonyl-L-α-aspartyl-L-valyl-L-α-aspartyl-L-cysteinyl-L-seryl-L-valyl-L-seryl-L-lysyl-L-α-glutamyl-L-cysteinyl-L-tryptophyl-L-seryl-L-valyl-L-cysteinyl-L-lysyl-L-α-aspartyl-L-leucyl-L-phenylalanylglycyl-L-valyl-L-α-aspartyl-L-arginylglycyl-L-lysyl-L-cysteinyl-L-methionylglycyl-L-lysyl-L-lysyl-L-cysteinyl-L-arginyl-L-cysteinyl-L-tyrosyl-, cyclic (7→28),(13→33),(17→35)-tris(disulfide)
CAS No: 129203-60-7 Catalog No: AG000YY4 MDL No:
Product Description
Catalog Number:
AG000YY4
Chemical Name:
L-Glutamine, 5-oxo-L-prolyl-L-phenylalanyl-L-threonyl-L-α-aspartyl-L-valyl-L-α-aspartyl-L-cysteinyl-L-seryl-L-valyl-L-seryl-L-lysyl-L-α-glutamyl-L-cysteinyl-L-tryptophyl-L-seryl-L-valyl-L-cysteinyl-L-lysyl-L-α-aspartyl-L-leucyl-L-phenylalanylglycyl-L-valyl-L-α-aspartyl-L-arginylglycyl-L-lysyl-L-cysteinyl-L-methionylglycyl-L-lysyl-L-lysyl-L-cysteinyl-L-arginyl-L-cysteinyl-L-tyrosyl-, cyclic (7→28),(13→33),(17→35)-tris(disulfide)
CAS Number:
129203-60-7
Molecular Formula:
C83H133N29O27S4
Molecular Weight:
2097.3822
IUPAC Name:
5-amino-2-[[2-[[10-[[6-amino-2-[[6-amino-2-[[2-[[2-[[7,34-bis(4-aminobutyl)-37-[[2-[[2-[[2-[[10-(4-aminobutyl)-22-[[3-carboxy-2-[[2-[[3-carboxy-2-[[3-hydroxy-2-[[2-[(5-oxopyrrolidine-2-carbonyl)amino]-3-phenylpropanoyl]amino]butanoyl]amino]propanoyl]amino]-3-methylbutanoyl]amino]propanoyl]amino]-7-(2-carboxyethyl)-13,19-bis(hydroxymethyl)-6,9,12,15,18,21-hexaoxo-16-propan-2-yl-1,2-dithia-5,8,11,14,17,20-hexazacyclotricosane-4-carbonyl]amino]-3-(1H-indol-3-yl)propanoyl]amino]-3-hydroxypropanoyl]amino]-3-methylbutanoyl]amino]-25-benzyl-13-(3-carbamimidamidopropyl)-16,31-bis(carboxymethyl)-28-(2-methylpropyl)-6,9,12,15,18,21,24,27,30,33,36-undecaoxo-19-propan-2-yl-1,2-dithia-5,8,11,14,17,20,23,26,29,32,35-undecazacyclooctatriacontane-4-carbonyl]amino]-4-methylsulfanylbutanoyl]amino]acetyl]amino]hexanoyl]amino]hexanoyl]amino]-7-(3-carbamimidamidopropyl)-6,9-dioxo-1,2-dithia-5,8-diazacycloundecane-4-carbonyl]amino]-3-(4-hydroxyphenyl)propanoyl]amino]-5-oxopentanoic acid
InChI:
InChI=1S/C179H274N50O55S7/c1-87(2)65-111-155(261)208-112(66-93-33-15-13-16-34-93)146(252)195-77-133(239)225-139(88(3)4)172(278)213-117(71-136(244)245)158(264)199-100(44-31-62-190-178(186)187)144(250)193-75-131(237)198-102(40-22-27-58-181)148(254)219-124(167(273)205-109(56-64-285-12)145(251)194-76-132(238)197-101(39-21-26-57-180)147(253)200-105(43-25-30-61-184)151(257)220-123-81-286-288-83-125(221-152(258)106(203-166(123)272)45-32-63-191-179(188)189)169(275)210-113(68-95-46-48-97(234)49-47-95)156(262)206-110(177(283)284)50-53-129(185)235)82-287-291-86-128(168(274)202-104(42-24-29-60-183)150(256)212-116(70-135(242)243)159(265)207-111)224-175(281)142(91(9)10)228-164(270)121(79-231)216-157(263)115(69-96-74-192-99-38-20-19-37-98(96)99)211-170(276)126-84-289-290-85-127(171(277)217-122(80-232)165(271)227-141(90(7)8)174(280)218-120(78-230)163(269)201-103(41-23-28-59-182)149(255)204-108(154(260)222-126)52-55-134(240)241)223-160(266)118(72-137(246)247)214-173(279)140(89(5)6)226-162(268)119(73-138(248)249)215-176(282)143(92(11)233)229-161(267)114(67-94-35-17-14-18-36-94)209-153(259)107-51-54-130(236)196-107/h13-20,33-38,46-49,74,87-92,100-128,139-143,192,230-234H,21-32,39-45,50-73,75-86,180-184H2,1-12H3,(H2,185,235)(H,193,250)(H,194,251)(H,195,252)(H,196,236)(H,197,238)(H,198,237)(H,199,264)(H,200,253)(H,201,269)(H,202,274)(H,203,272)(H,204,255)(H,205,273)(H,206,262)(H,207,265)(H,208,261)(H,209,259)(H,210,275)(H,211,276)(H,212,256)(H,213,278)(H,214,279)(H,215,282)(H,216,263)(H,217,277)(H,218,280)(H,219,254)(H,220,257)(H,221,258)(H,222,260)(H,223,266)(H,224,281)(H,225,239)(H,226,268)(H,227,271)(H,228,270)(H,229,267)(H,240,241)(H,242,243)(H,244,245)(H,246,247)(H,248,249)(H,283,284)(H4,186,187,190)(H4,188,189,191)
InChI Key:
VDNVVLOBNHIMQA-UHFFFAOYSA-N
SMILES:
NCCCCC1NC(=O)CNC(=O)C(CCCNC(=N)N)NC(=O)C(CC(=O)O)NC(=O)C(NC(=O)CNC(=O)C(Cc2ccccc2)NC(=O)C(NC(=O)C(NC(=O)C(NC(=O)CCSSCC(NC1=O)C(=O)NCC(=O)NCC(=O)NCC(=O)NCC(=O)NC1CSSCC(NC(=O)C(NC1=O)CCCNC(=N)N)C(=O)NCC(=O)NC(C(=O)O)CCC(=O)N)CCCCN)CC(=O)O)CC(C)C)C(C)C
Properties
Complexity:
9970
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
1
Defined Atom Stereocenter Count:
0
Defined Bond Stereocenter Count:
0
Exact Mass:
4228.826g/mol
Formal Charge:
0
Heavy Atom Count:
291
Hydrogen Bond Acceptor Count:
69
Hydrogen Bond Donor Count:
61
Isotope Atom Count:
0
Molecular Weight:
4230.876g/mol
Monoisotopic Mass:
4227.823g/mol
Rotatable Bond Count:
100
Topological Polar Surface Area:
1890A^2
Undefined Atom Stereocenter Count:
35
Undefined Bond Stereocenter Count:
0
XLogP3:
-22
Literature
| Title | Journal |
|---|---|
| Targeting KCa1.1 Channels with a Scorpion Venom Peptide for the Therapy of Rat Models of Rheumatoid Arthritis. | The Journal of pharmacology and experimental therapeutics 20180501 |
| Different expression of β subunits of the KCa1.1 channel by invasive and non-invasive human fibroblast-like synoviocytes. | Arthritis research & therapy 20160101 |
| Current understanding of iberiotoxin-resistant BK channels in the nervous system. | Frontiers in physiology 20140101 |
| Iberiotoxin-sensitive and -insensitive BK currents in Purkinje neuron somata. | Journal of neurophysiology 20130515 |
| Unoprostone isopropyl and metabolite M1 activate BK channels and prevent ET-1-induced [Ca²⁺]i increases in human trabecular meshwork and smooth muscle. | Investigative ophthalmology & visual science 20120807 |
| Upregulation of endothelium-derived hyperpolarizing factor compensates for the loss of nitric oxide in mesenteric arteries of Dahl salt-sensitive hypertensive rats. | Hypertension research : official journal of the Japanese Society of Hypertension 20120801 |
| Penitrem A as a tool for understanding the role of large conductance Ca(2+)/voltage-sensitive K(+) channels in vascular function. | The Journal of pharmacology and experimental therapeutics 20120801 |
| Blockade of ATP-sensitive potassium channels prevents the attenuation of the exercise pressor reflex by tempol in rats with ligated femoral arteries. | American journal of physiology. Heart and circulatory physiology 20120801 |
| Cyclic AMP-induced K+ secretion occurs independently of Cl- secretion in rat distal colon. | American journal of physiology. Cell physiology 20120801 |
| Disruption of TRPV1-mediated coupling of coronary blood flow to cardiac metabolism in diabetic mice: role of nitric oxide and BK channels. | American journal of physiology. Heart and circulatory physiology 20120715 |
| Flow-evoked vasodilation is blunted in penile arteries from Zucker diabetic fatty rats. | The journal of sexual medicine 20120701 |
| Chronic hypoxia suppresses pregnancy-induced upregulation of large-conductance Ca2+-activated K+ channel activity in uterine arteries. | Hypertension (Dallas, Tex. : 1979) 20120701 |
| Dietary obesity increases NO and inhibits BKCa-mediated, endothelium-dependent dilation in rat cremaster muscle artery: association with caveolins and caveolae. | American journal of physiology. Heart and circulatory physiology 20120615 |
| Reverse-mode NCX current in mouse airway smooth muscle: Na(+) and voltage dependence, contributions to Ca(2+) influx and contraction, and altered expression in a model of allergen-induced hyperresponsiveness. | Acta physiologica (Oxford, England) 20120601 |
| The contribution of d-tubocurarine-sensitive and apamin-sensitive K-channels to EDHF-mediated relaxation of mesenteric arteries from eNOS-/- mice. | Journal of cardiovascular pharmacology 20120501 |
| Perspective on the role of P2X-purinoceptor activation in human vas deferens contractility. | Experimental physiology 20120501 |
| Impaired β-adrenoceptor-induced relaxation in small mesenteric arteries from DOCA-salt hypertensive rats is due to reduced K(Ca) channel activity. | Pharmacological research 20120501 |
| Effects of preeclamptic plasma on potassium currents of human umbilical vein endothelial cells. | Reproductive sciences (Thousand Oaks, Calif.) 20120401 |
| H2O2-induced dilation in human coronary arterioles: role of protein kinase G dimerization and large-conductance Ca2+-activated K+ channel activation. | Circulation research 20120203 |
| P2Y1 receptor modulation of Ca2+-activated K+ currents in medium-sized neurons from neonatal rat striatal slices. | Journal of neurophysiology 20120201 |
| Hypotonicity-induced TRPV4 function in renal collecting duct cells: modulation by progressive cross-talk with Ca2+-activated K+ channels. | Cell calcium 20120201 |
| Magnesium increases iberiotoxin-sensitive large conductance calcium activated potassium currents on the basilar artery smooth muscle cells in rabbits. | Neurological research 20120101 |
| The relaxant action of nicorandil in bovine tracheal smooth muscle. | Pharmacology 20120101 |
| Fast-activating voltage- and calcium-dependent potassium (BK) conductance promotes bursting in pituitary cells: a dynamic clamp study. | The Journal of neuroscience : the official journal of the Society for Neuroscience 20111116 |
| Aβ inhibition of ionic conductance in mouse basal forebrain neurons is dependent upon the cellular prion protein PrPC. | The Journal of neuroscience : the official journal of the Society for Neuroscience 20111109 |
| Role of NKCC in BK channel-mediated net K⁺ secretion in the CCD. | American journal of physiology. Renal physiology 20111101 |
| Vasodilation of retinal arterioles induced by activation of BKCa channels is attenuated in diabetic rats. | European journal of pharmacology 20111101 |
| Two-pore domain K⁺ channels regulate membrane potential of isolated human articular chondrocytes. | The Journal of physiology 20111101 |
| Short-term synaptic plasticity regulates the level of olivocochlear inhibition to auditory hair cells. | The Journal of neuroscience : the official journal of the Society for Neuroscience 20111012 |
| Contribution of BK channels to action potential repolarisation at minimal cytosolic Ca2+ concentration in chromaffin cells. | Pflugers Archiv : European journal of physiology 20111001 |
| Characterization of P2Y receptors mediating ATP induced relaxation in guinea pig airway smooth muscle: involvement of prostaglandins and K+ channels. | Pflugers Archiv : European journal of physiology 20111001 |
| Vasoactivity of the gasotransmitters hydrogen sulfide and carbon monoxide in the chicken ductus arteriosus. | American journal of physiology. Regulatory, integrative and comparative physiology 20111001 |
| Role of perivascular adipose tissue-derived methyl palmitate in vascular tone regulation and pathogenesis of hypertension. | Circulation 20110906 |
| On the mode of action of emodepside: slow effects on membrane potential and voltage-activated currents in Ascaris suum. | British journal of pharmacology 20110901 |
| Genetic targeting and physiological features of VGLUT3+ amacrine cells. | Visual neuroscience 20110901 |
| Effects of potassium channel modulators on myogenic spontaneous phasic contractile activity in human detrusor from neurogenic patients. | BJU international 20110801 |
| The GPR55 agonist lysophosphatidylinositol directly activates intermediate-conductance Ca2+ -activated K+ channels. | Pflugers Archiv : European journal of physiology 20110801 |
| K(Ca)3.1 channels facilitate K+ secretion or Na+ absorption depending on apical or basolateral P2Y receptor stimulation. | The Journal of physiology 20110715 |
| Inhibition of Ca2+-activated large-conductance K+ channel activity alters synaptic AMPA receptor phenotype in mouse cerebellar stellate cells. | Journal of neurophysiology 20110701 |
| Functional and molecular characterization of maxi K+ -channels (BK(Ca)) in buffalo myometrium. | Animal reproduction science 20110701 |
| Intermittent hypoxia in rats increases myogenic tone through loss of hydrogen sulfide activation of large-conductance Ca(2+)-activated potassium channels. | Circulation research 20110610 |
| High glucose alters apoptosis and proliferation in HEK293 cells by inhibition of cloned BK Ca channel. | Journal of cellular physiology 20110601 |
| Activation of vascular BK channels by docosahexaenoic acid is dependent on cytochrome P450 epoxygenase activity. | Cardiovascular research 20110501 |
| Role of calcium-activated potassium channels in acetylcholine-induced vasodilation of rat retinal arterioles in vivo. | Naunyn-Schmiedeberg's archives of pharmacology 20110101 |
| Cytoprotective action of the potassium channel opener NS1619 under conditions of disrupted calcium homeostasis. | Pharmacological reports : PR 20110101 |
| Unoprostone reduces oxidative stress- and light-induced retinal cell death, and phagocytotic dysfunction, by activating BK channels. | Molecular vision 20110101 |
| Growth-dependent changes in the contribution of carbon monoxide to arteriolar function. | Journal of vascular research 20101201 |
| Modulation of adrenergic responses of human vas deferens by K+ channel inhibitors. | Urology 20101201 |
| Cortical up state activity is enhanced after seizures: a quantitative analysis. | Journal of clinical neurophysiology : official publication of the American Electroencephalographic Society 20101201 |
| Current profiles of astrocytes from the corpus callosum of newborn and 28-day-old rats. | Neuroscience letters 20101126 |
| Novel role of endothelial BKCa channels in altered vasoreactivity following hypoxia. | American journal of physiology. Heart and circulatory physiology 20101101 |
| Antecedent hydrogen sulfide elicits an anti-inflammatory phenotype in postischemic murine small intestine: role of BK channels. | American journal of physiology. Heart and circulatory physiology 20101101 |
| Increased excitability of cortical neurons induced by associative learning: an ex vivo study. | The European journal of neuroscience 20101101 |
| Mitochondrial monoamine oxidase-A-mediated hydrogen peroxide generation enhances 5-hydroxytryptamine-induced contraction of rat basilar artery. | British journal of pharmacology 20101101 |
| Modulators of BK and SK channels alter electrical activity in vitro in single vasopressin neurons isolated from the rat supraoptic nucleus. | Neuroscience letters 20101022 |
| Pre-synaptic BK channels selectively control glutamate versus GABA release from cortical and hippocampal nerve terminals. | Journal of neurochemistry 20101001 |
| Biophysical properties of human medulloblastoma cells. | The Journal of membrane biology 20101001 |
| Exploring the mechanism of endothelial involvement in acidosis-induced vasodilatation of aortic tissues from normal and diabetic rats. | European journal of pharmacology 20100910 |
| Ca(2+) and Ca(2+)-activated K(+) channels that support and modulate transmitter release at the olivocochlear efferent-inner hair cell synapse. | The Journal of neuroscience : the official journal of the Society for Neuroscience 20100908 |
| Methyl palmitate: a potent vasodilator released in the retina. | Investigative ophthalmology & visual science 20100901 |
| Large conductance Ca2+-activated K+ channels inhibit vagal acetylcholine release at the rabbit sinoatrial node. | Autonomic neuroscience : basic & clinical 20100825 |
| Inhibition of inflammatory pain by activating B-type natriuretic peptide signal pathway in nociceptive sensory neurons. | The Journal of neuroscience : the official journal of the Society for Neuroscience 20100811 |
| Differential involvement of potassium channel subtypes in early and late sepsis-induced hyporesponsiveness to vasoconstrictors. | Journal of cardiovascular pharmacology 20100801 |
| Endothelium-derived nitric oxide inhibits the relaxation of the porcine coronary artery to natriuretic peptides by desensitizing big conductance calcium-activated potassium channels of vascular smooth muscle. | The Journal of pharmacology and experimental therapeutics 20100701 |
| Localization of large conductance calcium-activated potassium channels and their effect on calcitonin gene-related peptide release in the rat trigemino-neuronal pathway. | Neuroscience 20100602 |
| Response of chicken ductus arteriosus to hypercarbic and normocarbic acidosis. | Neonatology 20100601 |
| N-arachidonoyl glycine, an endogenous lipid that acts as a vasorelaxant via nitric oxide and large conductance calcium-activated potassium channels. | British journal of pharmacology 20100601 |
| Expression of neuronal nitric oxide synthase in rabbit carotid body glomus cells regulates large-conductance Ca2+-activated potassium currents. | Journal of neurophysiology 20100601 |
| Dendritic Kv3.3 potassium channels in cerebellar purkinje cells regulate generation and spatial dynamics of dendritic Ca2+ spikes. | Journal of neurophysiology 20100601 |
| Magnesium lithospermate B dilates mesenteric arteries by activating BKCa currents and contracts arteries by inhibiting K(V) currents. | Acta pharmacologica Sinica 20100601 |
| Effects of bladder outlet obstruction on properties of Ca2+-activated K+ channels in rat bladder. | American journal of physiology. Regulatory, integrative and comparative physiology 20100501 |
| Activation of cloned BK(Ca) channels in nitric oxide-induced apoptosis of HEK293 cells. | Apoptosis : an international journal on programmed cell death 20100401 |
| BK channel activation by NS11021 decreases excitability and contractility of urinary bladder smooth muscle. | American journal of physiology. Regulatory, integrative and comparative physiology 20100201 |
| The intermediate conductance Ca2+-activated K+ channel inhibitor TRAM-34 stimulates proliferation of breast cancer cells via activation of oestrogen receptors. | British journal of pharmacology 20100201 |
| Vasorelaxing action of vasonatrin peptide is associated with activation of large-conductance Ca(2+)-activated potassium channels in vascular smooth muscle cells. | Physiological research 20100101 |
| Complex interactions of NO/cGMP/PKG systems on Ca2+ signaling in afferent arteriolar vascular smooth muscle. | American journal of physiology. Heart and circulatory physiology 20100101 |
| Role of Ca2+-activated K+ channels in catecholamine release from in vivo rat adrenal medulla. | Neurochemistry international 20100101 |
| Block of mouse Slo1 and Slo3 K+ channels by CTX, IbTX, TEA, 4-AP and quinidine. | Channels (Austin, Tex.) 20100101 |
| Activation of endothelial BKCa channels causes pulmonary vasodilation. | Vascular pharmacology 20100101 |
| BK channels mediate cholinergic inhibition of high frequency cochlear hair cells. | PloS one 20100101 |
| Mutation in the myelin proteolipid protein gene alters BK and SK channel function in the caudal medulla. | Respiratory physiology & neurobiology 20091231 |
| A large-conductance (BK) potassium channel subtype affects both growth and mineralization of human osteoblasts. | American journal of physiology. Cell physiology 20091201 |
| Large conductance calcium-activated potassium channels (BKCa) modulate trigeminovascular nociceptive transmission. | Cephalalgia : an international journal of headache 20091201 |
| Impaired function of coronary BK(Ca) channels in metabolic syndrome. | American journal of physiology. Heart and circulatory physiology 20091101 |
| Comparative roles of ATP-sensitive K+ channels and Ca2+-activated BK+ channels in posthypoxic hyperexcitability and rapid hypoxic preconditioning in hippocampal CA1 pyramidal neurons in vitro. | Neuroscience letters 20090918 |
| Mechanism of differential cardiovascular response to propofol in Dahl salt-sensitive, Brown Norway, and chromosome 13-substituted consomic rat strains: role of large conductance Ca2+ and voltage-activated potassium channels. | The Journal of pharmacology and experimental therapeutics 20090901 |
| MaxiK potassium channels in the function of chemoreceptor cells of the rat carotid body. | American journal of physiology. Cell physiology 20090901 |
| Inhibition of vascular calcium-gated chloride currents by blockers of KCa1.1, but not by modulators of KCa2.1 or KCa2.3 channels. | British journal of pharmacology 20090901 |
| Activation of the BK(Ca) channel increases outflow facility and decreases trabecular meshwork cell volume. | Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics 20090801 |
| Facilitation of acetylcholine secretion in mouse motor synapses caused by calcium release from depots upon activation of L-type calcium channels. | Bulletin of experimental biology and medicine 20090801 |
| Abnormal activation of potassium channels in aortic smooth muscle of rats with peritonitis-induced septic shock. | Shock (Augusta, Ga.) 20090701 |
| Plasticity and emerging role of BKCa channels in nociceptive control in neuropathic pain. | Journal of neurochemistry 20090701 |
| Chronic nicotine blunts hypoxic sensitivity in perinatal rat adrenal chromaffin cells via upregulation of KATP channels: role of alpha7 nicotinic acetylcholine receptor and hypoxia-inducible factor-2alpha. | The Journal of neuroscience : the official journal of the Society for Neuroscience 20090603 |
| Compartmentalized beta subunit distribution determines characteristics and ethanol sensitivity of somatic, dendritic, and terminal large-conductance calcium-activated potassium channels in the rat central nervous system. | The Journal of pharmacology and experimental therapeutics 20090601 |
| Synthesis of an iberiotoxin derivative by chemical ligation: a method for improved yields of cysteine-rich scorpion toxin peptides. | Peptides 20090601 |
| Ca2+-activated K+ current in freshly isolated c-Kit positive cells in guinea-pig stomach. | Journal of Korean medical science 20090601 |
| Homeostatic synapse-driven membrane plasticity in nucleus accumbens neurons. | The Journal of neuroscience : the official journal of the Society for Neuroscience 20090506 |
| Ca2+-activated K+ channels in gonadotropin-releasing hormone-stimulated mouse gonadotrophs. | Endocrinology 20090501 |
| Epigallocatechin-3-gallate relaxes the isolated bovine ophthalmic artery: involvement of phosphoinositide 3-kinase-Akt-nitric oxide/cGMP signalling pathway. | European journal of pharmacology 20090417 |
| Epoxyeicosatrienoic acid activates BK channels in the cortical collecting duct. | Journal of the American Society of Nephrology : JASN 20090301 |
| Calcium ions regulate K⁺ uptake into brain mitochondria: the evidence for a novel potassium channel. | International journal of molecular sciences 20090301 |
| Inhibitory effect of genistein on agonist-induced modulation of vascular contractility. | Molecules and cells 20090227 |
| Adaptative modifications of right coronary myocytes voltage-gated K+ currents in rat with hypoxic pulmonary hypertension. | Pflugers Archiv : European journal of physiology 20090201 |
| Impaired mitochondria-dependent vasodilation in cerebral arteries of Zucker obese rats with insulin resistance. | American journal of physiology. Regulatory, integrative and comparative physiology 20090201 |
| Activation of stretch-activated channels and maxi-K+ channels by membrane stress of human lamina cribrosa cells. | Investigative ophthalmology & visual science 20090101 |
| Interaction between P450 eicosanoids and nitric oxide in the control of arterial tone in mice. | Arteriosclerosis, thrombosis, and vascular biology 20090101 |
| Relaxing effects of 17(18)-EpETE on arterial and airway smooth muscles in human lung. | American journal of physiology. Lung cellular and molecular physiology 20090101 |
| Molecular mechanisms of paraptosis induction: implications for a non-genetically modified tumor vaccine. | PloS one 20090101 |
| Role of potassium channels in the relaxant effect of levosimendan in guinea pig tracheal preparations. | Pharmacological reports : PR 20090101 |
| Role of KCNMA1 gene in breast cancer invasion and metastasis to brain. | BMC cancer 20090101 |
| [Role of Ca(2+)-activated potassium channels with high-conductivity in hypoxic preconditioning and posthypoxic hyperexcitability in CA1 hippocampal neurons in vitro]. | Zhurnal vysshei nervnoi deiatelnosti imeni I P Pavlova 20090101 |
| Effects of taurine on aortic rings isolated from fructose-fed insulin resistance Sprague-Dawley rat are changed. | Cardiovascular drugs and therapy 20081201 |
| Activation of endogenous GABAA channels on airway smooth muscle potentiates isoproterenol-mediated relaxation. | American journal of physiology. Lung cellular and molecular physiology 20081201 |
| Ghrelin signalling in guinea-pig femoral artery smooth muscle cells. | Acta physiologica (Oxford, England) 20081101 |
| Presynaptic large-conductance calcium-activated potassium channels control synaptic transmission in the superficial dorsal horn of the mouse. | Neuroscience letters 20081017 |
| 1-[1-Hexyl-6-(methyloxy)-1H-indazol-3-yl]-2-methyl-1-propanone, a potent and highly selective small molecule blocker of the large-conductance voltage-gated and calcium-dependent K+ channel. | The Journal of pharmacology and experimental therapeutics 20081001 |
| Hydrogen peroxide potentiates the EDHF phenomenon by promoting endothelial Ca2+ mobilization. | Arteriosclerosis, thrombosis, and vascular biology 20081001 |
| Beta-adrenergic relaxation of mouse urinary bladder smooth muscle in the absence of large-conductance Ca2+-activated K+ channel. | American journal of physiology. Renal physiology 20081001 |
| Nitric oxide decreases the excitability of interstitial cells of Cajal through activation of the BK channel. | Journal of cellular and molecular medicine 20080901 |
| Monoaminergic modulation of the Na+-activated K+ channel in Kenyon cells isolated from the mushroom body of the cricket (Gryllus bimaculatus) brain. | Journal of neurophysiology 20080901 |
| NFATc3 regulates BK channel function in murine urinary bladder smooth muscle. | American journal of physiology. Cell physiology 20080901 |
| Aldosterone increases KCa1.1 (BK) channel-mediated colonic K+ secretion. | The Journal of physiology 20080901 |
| Temporal processing across multiple topographic maps in the electrosensory system. | Journal of neurophysiology 20080801 |
| Calcium-activated potassium channels contribute to human skeletal muscle microvascular endothelial dysfunction related to cardiopulmonary bypass. | Surgery 20080801 |
| NO-induced regulation of human trabecular meshwork cell volume and aqueous humor outflow facility involve the BKCa ion channel. | American journal of physiology. Cell physiology 20080601 |
| Iberiotoxin-sensitive large conductance Ca2+ -dependent K+ (BK) channels regulate the spike configuration in the burst firing of cerebellar Purkinje neurons. | Brain research 20080530 |
| C-type natriuretic peptide hyperpolarizes and relaxes human penile resistance arteries. | The journal of sexual medicine 20080501 |
| Cytochrome P-450 metabolites of 2-arachidonoylglycerol play a role in Ca2+-induced relaxation of rat mesenteric arteries. | American journal of physiology. Heart and circulatory physiology 20080501 |
| Critical role for small and large conductance calcium-dependent potassium channels in endotoxemia and TNF toxicity. | Shock (Augusta, Ga.) 20080501 |
| Ionic basis of ON and OFF persistent activity in layer III lateral entorhinal cortical principal neurons. | Journal of neurophysiology 20080401 |
| Differential effects of estrogen and progesterone on potassium channels expressed in Xenopus oocytes. | Steroids 20080301 |
| Effects of omega-hydroxylase product on distal human pulmonary arteries. | American journal of physiology. Heart and circulatory physiology 20080301 |
| Riluzole-induced block of voltage-gated Na+ current and activation of BKCa channels in cultured differentiated human skeletal muscle cells. | Life sciences 20080102 |
| Vertebrate rod photoreceptors express both BK and IK calcium-activated potassium channels, but only BK channels are involved in receptor potential regulation. | Journal of neuroscience research 20080101 |
| Role of 20-HETE in the hypoxia-induced activation of Ca2+-activated K+ channel currents in rat cerebral arterial muscle cells. | American journal of physiology. Heart and circulatory physiology 20080101 |
| Potentiation of potassium currents by beta-adrenoceptor agonists in human urinary bladder smooth muscle cells: a possible electrical mechanism of relaxation. | Pharmacology 20080101 |
| Resveratrol inhibits electrical activity and insulin release from insulinoma cells by block of voltage-gated Ca+ channels and swelling-dependent Cl- currents. | Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 20080101 |
| Role of TASK2 in the control of apoptotic volume decrease in proximal kidney cells. | The Journal of biological chemistry 20071214 |
| Role of K(+) channels in the regulation of electrical spontaneous activity of the mouse small intestine. | Pflugers Archiv : European journal of physiology 20071201 |
| Acute antihypertensive action of Tempol in the spontaneously hypertensive rat. | American journal of physiology. Heart and circulatory physiology 20071201 |
| Effects of K+ channel modulators on oscillatory contractions in sinoaortic denervated rat aortas. | Biological & pharmaceutical bulletin 20071101 |
| The structural and functional differentiation of hair cells in a lizard's basilar papilla suggests an operational principle of amniote cochleas. | The Journal of neuroscience : the official journal of the Society for Neuroscience 20071031 |
| Adrenomedullin reduces gender-dependent loss of hypotensive cerebrovasodilation after newborn brain injury through activation of ATP-dependent K channels. | Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 20071001 |
| Heat shock proteins and p53 play a critical role in K+ channel-mediated tumor cell proliferation and apoptosis. | Apoptosis : an international journal on programmed cell death 20071001 |
| Functional effects of 20-HETE on human bronchi: hyperpolarization and relaxation due to BKCa channel activation. | American journal of physiology. Lung cellular and molecular physiology 20071001 |
| Role of Ca2+-dependent potassium channels in in vitro anandamide-mediated mesenteric vasorelaxation in rats with biliary cirrhosis. | Liver international : official journal of the International Association for the Study of the Liver 20071001 |
| Functional characterization of voltage-gated K+ channels in mouse pulmonary artery smooth muscle cells. | American journal of physiology. Cell physiology 20070901 |
| Contribution of epoxyeicosatrienoic acids to flow-induced dilation in arteries of male ERalpha knockout mice: role of aromatase. | American journal of physiology. Regulatory, integrative and comparative physiology 20070901 |
| Different responses to angiotensin-(1-7) in young, aged and diabetic rabbit corpus cavernosum. | Pharmacological research 20070901 |
| Prostaglandin E2 enhances acetylcholine-induced, Ca2+-dependent ionic currents in swine tracheal mucous gland cells. | The Journal of pharmacology and experimental therapeutics 20070801 |
| Characterization of voltage-and Ca2+-activated K+ channels in rat dorsal root ganglion neurons. | Journal of cellular physiology 20070801 |
| Modulation by simvastatin of iberiotoxin-sensitive, Ca2+-activated K+ channels of porcine coronary artery smooth muscle cells. | British journal of pharmacology 20070801 |
| Role of BK channels in testosterone-induced relaxation of the aorta in spontaneously hypertensive rats. | Biological & pharmaceutical bulletin 20070801 |
| Large-conductance calcium-activated potassium channel activity is absent in human and mouse neutrophils and is not required for innate immunity. | American journal of physiology. Cell physiology 20070701 |
| A-272651, a nonpeptidic blocker of large-conductance Ca2+-activated K+ channels, modulates bladder smooth muscle contractility and neuronal action potentials. | British journal of pharmacology 20070701 |
| Changes in stretch-induced tone induced by intracellular acidosis in rabbit basilar artery: effects on BKCa channel activity. | Vascular pharmacology 20070701 |
| K+ channel modulation of slow wave activity in the guinea-pig prostate. | British journal of pharmacology 20070701 |
| Characterization of 14,15-epoxyeicosatrienoyl-sulfonamides as 14,15-epoxyeicosatrienoic acid agonists: use for studies of metabolism and ligand binding. | The Journal of pharmacology and experimental therapeutics 20070601 |
| Depletion of membrane cholesterol eliminates the Ca2+-activated component of outward potassium current and decreases membrane capacitance in rat uterine myocytes. | The Journal of physiology 20070601 |
| Synaptic plasticity in myenteric neurons of the guinea-pig distal colon: presynaptic mechanisms of inflammation-induced synaptic facilitation. | The Journal of physiology 20070601 |
| Firing properties of GABAergic versus non-GABAergic vestibular nucleus neurons conferred by a differential balance of potassium currents. | Journal of neurophysiology 20070601 |
| Relaxing effects of 5-oxo-ETE on human bronchi involve BK Ca channel activation. | Prostaglandins & other lipid mediators 20070601 |
| BK potassium channels facilitate high-frequency firing and cause early spike frequency adaptation in rat CA1 hippocampal pyramidal cells. | The Journal of physiology 20070501 |
| Cellular and molecular effects of unoprostone as a BK channel activator. | Biochimica et biophysica acta 20070501 |
| Investigation of the vasorelaxant effects of 3-(5'-hydroxymethyl-2'-furyl)-1-benzyl indazole (YC-1) and diethylamine/nitric oxide (DEA/NO) on the human radial artery used as coronary bypass graft. | Canadian journal of physiology and pharmacology 20070501 |
| Bradykinin activates calcium-dependent potassium channels in cultured human airway smooth muscle cells. | American journal of physiology. Lung cellular and molecular physiology 20070401 |
| Functional contribution of the endothelial component to the vasorelaxing effect of resveratrol and NS 1619, activators of the large-conductance calcium-activated potassium channels. | Naunyn-Schmiedeberg's archives of pharmacology 20070301 |
| Electromechanical and pharmacomechanical signalling pathways for conducted vasodilatation along endothelium of hamster feed arteries. | The Journal of physiology 20070215 |
| Matrix metalloproteinase 2-induced venous dilation via hyperpolarization and activation of K+ channels: relevance to varicose vein formation. | Journal of vascular surgery 20070201 |
| Human monocytes kill M-CSF-expressing glioma cells by BK channel activation. | Laboratory investigation; a journal of technical methods and pathology 20070201 |
| Endothelium-independent relaxation to raloxifene in porcine coronary artery. | European journal of pharmacology 20070126 |
| The coupling of acetylcholine-induced BK channel and calcium channel in guinea pig saccular type II vestibular hair cells. | Brain research 20070119 |
| The dietary flavonoid quercetin activates BKCa currents in coronary arteries via production of H2O2. Role in vasodilatation. | Cardiovascular research 20070115 |
| Activation of Ca2+ -activated potassium channels is involved in lysophosphatidylcholine-induced monocyte adhesion to endothelial cells. | Atherosclerosis 20070101 |
| Effects of capsazepine on human small airway responsiveness unravel a novel class of bronchorelaxants. | Pulmonary pharmacology & therapeutics 20070101 |
| Altered ion transport and responsiveness to methacholine and hyperosmolarity in air interface-cultured guinea-pig tracheal epithelium. | Journal of pharmacological and toxicological methods 20070101 |
| Frequency encoding of cholinergic- and purinergic-mediated signaling to mouse urinary bladder smooth muscle: modulation by BK channels. | American journal of physiology. Regulatory, integrative and comparative physiology 20070101 |
| Renovascular BK(Ca) channels are not activated in vivo under resting conditions and during agonist stimulation. | American journal of physiology. Regulatory, integrative and comparative physiology 20070101 |
| Ca2+-activated K+ channels involved in duodenal dismotility induced by ethanol. | Alcohol and alcoholism (Oxford, Oxfordshire) 20070101 |
| [Electrophysiological study on rat conduit pulmonary artery smooth muscle cells under normoxia and acute hypoxia]. | Sheng li xue bao : [Acta physiologica Sinica] 20061025 |
| Muscarinic regulation of neonatal rat bladder spontaneous contractions. | American journal of physiology. Regulatory, integrative and comparative physiology 20061001 |
| Reversible inhibition of the platelet procoagulant response through manipulation of the Gardos channel. | Blood 20061001 |
| Rat mesenteric arterial dilator response to 11,12-epoxyeicosatrienoic acid is mediated by activating heme oxygenase. | American journal of physiology. Heart and circulatory physiology 20061001 |
| Effect of uroguanylin on potassium and bicarbonate transport in rat renal tubules. | Canadian journal of physiology and pharmacology 20061001 |
| Modulation by homocysteine of the iberiotoxin-sensitive, Ca2+ -activated K+ channels of porcine coronary artery smooth muscle cells. | European journal of pharmacology 20060928 |
| Activation of the iberiotoxin-sensitive BKCa channels by salvianolic acid B of the porcine coronary artery smooth muscle cells. | European journal of pharmacology 20060928 |
| Substituted adamantyl-urea inhibitors of the soluble epoxide hydrolase dilate mesenteric resistance vessels. | The Journal of pharmacology and experimental therapeutics 20060901 |
| Fast cholinergic efferent inhibition in guinea pig outer hair cells. | Brain research 20060802 |
| Membrane potassium currents in human radial artery and their regulation by nitric oxide donor. | Cardiovascular research 20060715 |
| Pharmaco-behavioural evidence indicating a complex role for ryanodine receptor calcium release channels in memory processing for a passive avoidance task. | Neurobiology of learning and memory 20060701 |
| Adenosine2A receptor vasodilation of rat preglomerular microvessels is mediated by EETs that activate the cAMP/PKA pathway. | American journal of physiology. Renal physiology 20060701 |
| Calcium-regulated potassium currents secure respiratory rhythm generation after loss of glycinergic inhibition. | The European journal of neuroscience 20060701 |
| Pharmacological evidence for the participation of NO-cyclic GMP-PKG-K+ channel pathway in the antiallodynic action of resveratrol. | Pharmacology, biochemistry, and behavior 20060701 |
| Effects of the abused inhalant toluene on ethanol-sensitive potassium channels expressed in oocytes. | Brain research 20060504 |
| Methanol extract of Terminalia superba induces endothelium-independent relaxation of rat thoracic aorta. | Die Pharmazie 20060501 |
| Norepinephrine activates store-operated Ca2+ entry coupled to large-conductance Ca2+-activated K+ channels in rat pinealocytes. | American journal of physiology. Cell physiology 20060401 |
| Oxygen tension modulates the expression of pulmonary vascular BKCa channel alpha- and beta-subunits. | American journal of physiology. Lung cellular and molecular physiology 20060401 |
| Alpha-latrotoxin induces exocytosis by inhibition of voltage-dependent K+ channels and by stimulation of L-type Ca2+ channels via latrophilin in beta-cells. | The Journal of biological chemistry 20060303 |
| Ca2+-activated K+ (KCa) channels are involved in the relaxations elicited by sildenafil in penile resistance arteries. | European journal of pharmacology 20060215 |
| Nitroglycerin-induced release of calcitonin gene-related peptide from sensory nerves attenuates the development of nitrate tolerance. | Journal of cardiovascular pharmacology 20060201 |
| Single transmembrane domain insulin-like growth factor-II/mannose-6-phosphate receptor regulates central cholinergic function by activating a G-protein-sensitive, protein kinase C-dependent pathway. | The Journal of neuroscience : the official journal of the Society for Neuroscience 20060111 |
| Involvement of guanylyl cyclase, protein kinase A and Na+ K+ ATPase in relaxations of bovine isolated bronchioles induced by GEA 3175, an NO donor. | Pulmonary pharmacology & therapeutics 20060101 |
| The cellular mechanisms by which adenosine evokes release of nitric oxide from rat aortic endothelium. | The Journal of physiology 20060101 |
| Synthesis of a biotin derivative of iberiotoxin: binding interactions with streptavidin and the BK Ca2+-activated K+ channel expressed in a human cell line. | Bioconjugate chemistry 20060101 |
| Contribution of BK(Ca)-channel activity in human cardiac fibroblasts to electrical coupling of cardiomyocytes-fibroblasts. | The Journal of membrane biology 20060101 |
| Ca2+-activated K+-current density is correlated with soma size in rat vestibular-afferent neurons in culture. | Journal of neurophysiology 20051201 |
| Calcium- and metabolic state-dependent modulation of the voltage-dependent Kv2.1 channel regulates neuronal excitability in response to ischemia. | The Journal of neuroscience : the official journal of the Society for Neuroscience 20051130 |
| Ca2+-dependent K+ channels are targets for bradykinin B1 receptor ligands and for lipopolysaccharide in the rat aorta. | European journal of pharmacology 20051121 |
| The properties of ACh-induced BK currents in guinea pig type II vestibular hair cells. | Hearing research 20051101 |
| Functional coupling of beta3-adrenoceptors and large conductance calcium-activated potassium channels in human uterine myocytes. | The Journal of clinical endocrinology and metabolism 20051001 |
| Ryanodine receptors and BK channels act as a presynaptic depressor of neurotransmission in cochlear inner hair cells. | The European journal of neuroscience 20050901 |
| Effect of progesterone on calcium activated potassium currents and intracellular calcium in guinea pig colon myocytes. | Methods and findings in experimental and clinical pharmacology 20050901 |
| Involvement of cyclic AMP-dependent and -independent mechanisms in the relaxation of rat detrusor muscle via beta-adrenoceptors. | European journal of pharmacology 20050822 |
| Evidence in favor of a calcium-sensing receptor in arterial endothelial cells: studies with calindol and Calhex 231. | Circulation research 20050819 |
| Role of the C-terminus of the high-conductance calcium-activated potassium channel in channel structure and function. | Biochemistry 20050802 |
| Negative feedback regulation of nerve-mediated contractions by KCa channels in mouse urinary bladder smooth muscle. | American journal of physiology. Regulatory, integrative and comparative physiology 20050801 |
| Sulfhydryl oxidation reduces hippocampal susceptibility to hypoxia-induced spreading depression by activating BK channels. | Journal of neurophysiology 20050801 |
| Bradykinin-induced, endothelium-dependent responses in porcine coronary arteries: involvement of potassium channel activation and epoxyeicosatrienoic acids. | British journal of pharmacology 20050701 |
| The effect of a hyposmotic shock and purinergic agonists on K+(Rb+) efflux from cultured human breast cancer cells. | Biochimica et biophysica acta 20050615 |
| Contribution of different Ca-activated K channels to the first phase of the response to TRH in clonal rat anterior pituitary cells. | Acta physiologica Scandinavica 20050601 |
| Specific functions of synaptically localized potassium channels in synaptic transmission at the neocortical GABAergic fast-spiking cell synapse. | The Journal of neuroscience : the official journal of the Society for Neuroscience 20050525 |
| Dual impact of a nitric oxide donor, GEA 3175, in human pulmonary smooth muscle. | European journal of pharmacology 20050523 |
| Decreases in CaMKII activity trigger persistent potentiation of intrinsic excitability in spontaneously firing vestibular nucleus neurons. | Neuron 20050519 |
| Properties of BK(Ca) channels in oral keratinocytes. | Journal of dental research 20050501 |
| Stimulation of cannabinoid (CB1) and prostanoid (EP2) receptors opens BKCa channels and relaxes ocular trabecular meshwork. | Experimental eye research 20050501 |
| Stable 5,6-epoxyeicosatrienoic acid analog relaxes coronary arteries through potassium channel activation. | Hypertension (Dallas, Tex. : 1979) 20050401 |
| Ca2+-dependent K+ channels from rat olfactory cilia characterized in planar lipid bilayers. | FEBS letters 20050314 |
| Effects of NS1608, a BK(Ca) channel agonist, on the contractility of guinea-pig urinary bladder in vitro. | British journal of pharmacology 20050301 |
| Hydrogen peroxide acts as both vasodilator and vasoconstrictor in the control of perfused mouse mesenteric resistance arteries. | Journal of hypertension 20050301 |
| Characterization of ionic currents in human mesenchymal stem cells from bone marrow. | Stem cells (Dayton, Ohio) 20050301 |
| Dynamics of fast synaptic excitation during trains of stimulation in myenteric neurons of guinea-pig ileum. | Autonomic neuroscience : basic & clinical 20050207 |
| Endothelin-1-induced proliferation of human endothelial cells depends on activation of K+ channels and Ca+ influx. | Acta physiologica Scandinavica 20050201 |
| Homogeneous distribution of large-conductance calcium-dependent potassium channels on soma and apical dendrite of rat neocortical layer 5 pyramidal neurons. | The European journal of neuroscience 20050201 |
| Electrophysiological properties of pluripotent human and mouse embryonic stem cells. | Stem cells (Dayton, Ohio) 20050101 |
| Nitric oxide stimulates a large-conductance Ca-activated K+ channel in human skin fibroblasts through protein kinase G pathway. | Skin pharmacology and physiology 20050101 |
| Description and role in proliferation of iberiotoxin-sensitive currents in different human mammary epithelial normal and cancerous cells. | Biochimica et biophysica acta 20041215 |
| Inferior olive oscillations gate transmission of motor cortical activity to the cerebellum. | The Journal of neuroscience : the official journal of the Society for Neuroscience 20041215 |
| The influence of hypotonicity on large-conductance calcium-activated potassium channels in human retinal pigment epithelial cells. | Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics 20041201 |
| Role for calcium-activated potassium channels (BK) in growth control of human malignant glioma cells. | Journal of neuroscience research 20041015 |
| Activation of iberiotoxin-sensitive, Ca2+-activated K+ channels of porcine isolated left anterior descending coronary artery by diosgenin. | European journal of pharmacology 20041011 |
| 17 Beta-estradiol prevents focal cerebral ischemic damages via activation of Akt and CREB in association with reduced PTEN phosphorylation in rats. | Fundamental & clinical pharmacology 20041001 |
| Lys-[Leu8,des-Arg9]-bradykinin blocks lipopolysaccharide-induced SHR aorta hyperpolarization by inhibition of Ca(++)- and ATP-dependent K+ channels. | European journal of pharmacology 20040913 |
| Visceral periadventitial adipose tissue regulates arterial tone of mesenteric arteries. | Hypertension (Dallas, Tex. : 1979) 20040901 |
| Pharmacological evidence for a key role of voltage-gated K+ channels in the function of rat aortic smooth muscle cells. | British journal of pharmacology 20040901 |
| Muscarinic receptor modulation of slow afterhyperpolarization and phasic firing in rat supraoptic nucleus neurons. | The Journal of neuroscience : the official journal of the Society for Neuroscience 20040901 |
| Anti-apoptotic action of (2S,3S,4R)-N'-cyano-N-(6-amino-3,4-dihydro-3-hydroxy-2-methyl-2-dimethoxymethyl-2H-benzopyran-4-yl)-N'-benzylguanidine (KR-31378) by suppression of the phosphatase and tensin homolog deleted from chromosome 10 phosphorylation and increased phosphorylation of casein kinase2/Akt/ cyclic AMP response element binding protein via maxi-K channel opening in neuronal cells. | European journal of pharmacology 20040830 |
| Preferential expression and function of voltage-gated, O2-sensitive K+ channels in resistance pulmonary arteries explains regional heterogeneity in hypoxic pulmonary vasoconstriction: ionic diversity in smooth muscle cells. | Circulation research 20040806 |
| Kv3 K+ channels enable burst output in rat cerebellar Purkinje cells. | The European journal of neuroscience 20040801 |
| [The mechanisms of short-term forms of synaptic plasticity]. | Rossiiskii fiziologicheskii zhurnal imeni I.M. Sechenova 20040801 |
| Junctional and nonjunctional effects of heptanol and glycyrrhetinic acid derivates in rat mesenteric small arteries. | British journal of pharmacology 20040701 |
| Contribution of Ca2+-activated K+ channels to hyperpolarizing after-potentials and discharge pattern in rat supraoptic neurones. | Journal of neuroendocrinology 20040701 |
| Hypoxia-induced inhibition of whole cell membrane currents and ion transport of A549 cells. | American journal of physiology. Lung cellular and molecular physiology 20040601 |
| Effects of intracellular stores and extracellular Ca(2+) on Ca(2+)-activated K(+) currents in mature mouse inner hair cells. | The Journal of physiology 20040601 |
| Relaxation of rabbit cavernous smooth muscle to 17beta-estradiol: a non-genomic, NO-independent mechanism. | Asian journal of andrology 20040601 |
| Endothelium-dependent responses in human isolated thyroid arteries from donors. | The Journal of endocrinology 20040601 |
| Synthesis and biological activity of novel substituted benzanilides as potassium channel activators. V. | European journal of medicinal chemistry 20040601 |
| Levosimendan interacts with potassium channel blockers in human saphenous veins. | Basic & clinical pharmacology & toxicology 20040601 |
| MaxiK channel-triggered negative feedback system is preserved in the urinary bladder smooth muscle from streptozotocin-induced diabetic rats. | Journal of smooth muscle research = Nihon Heikatsukin Gakkai kikanshi 20040601 |
| BK potassium channels control transmitter release at CA3-CA3 synapses in the rat hippocampus. | The Journal of physiology 20040515 |
| Function and clustered expression of MaxiK channels in cerebral myocytes remain intact with aging. | Experimental gerontology 20040501 |
| Beta1-adrenoceptor-mediated relaxation with isoprenaline and the role of MaxiK channels in guinea-pig esophageal smooth muscle. | Journal of smooth muscle research = Nihon Heikatsukin Gakkai kikanshi 20040401 |
| Effect of blockers of potential-dependent and calcium-activated K+-channels on facilitation of neuromuscular transmission. | Bulletin of experimental biology and medicine 20040401 |
| Regulation of Ca2+-dependent K+ current by alphavbeta3 integrin engagement in vascular endothelium. | The Journal of biological chemistry 20040326 |
| Membrane-potential-dependent inhibition of platelet adhesion to endothelial cells by epoxyeicosatrienoic acids. | Arteriosclerosis, thrombosis, and vascular biology 20040301 |
| Vasodilatory mechanism of unoprostone isopropyl on isolated rabbit ciliary artery. | Current eye research 20040301 |
| 8Br-cGMP mediates relaxation of tracheal smooth muscle through PKA. | Biochemical and biophysical research communications 20040206 |
| Role of membrane potential and expression of endothelial factors in restenosis after angioplasty in SHR. | Hypertension (Dallas, Tex. : 1979) 20040101 |
| Maturation of spiking activity in trout retinal ganglion cells coincides with upregulation of Kv3.1- and BK-related potassium channels. | Journal of neuroscience research 20040101 |
| BK channels mediate the voltage-dependent outward current in type I spiral ligament fibrocytes. | Hearing research 20040101 |
| Novel form of LTD induced by transient, partial inhibition of the Na,K-pump in rat hippocampal CA1 cells. | Journal of neurophysiology 20040101 |
| Combined oxygen and glucose sensing in the carotid body. | Undersea & hyperbaric medicine : journal of the Undersea and Hyperbaric Medical Society, Inc 20040101 |
| Chronic intrauterine pulmonary hypertension compromises fetal pulmonary artery smooth muscle cell O2 sensing. | American journal of physiology. Lung cellular and molecular physiology 20031201 |
| G protein-coupled endothelial receptor for atypical cannabinoid ligands modulates a Ca2+-dependent K+ current. | The Journal of biological chemistry 20031114 |
| Long-lasting increases in intrinsic excitability triggered by inhibition. | Neuron 20031030 |
| Gamma-dendrotoxin blocks large conductance Ca2+-activated K+ channels in neuroblastoma cells. | Life sciences 20030919 |
| Elevated glucose impairs cAMP-mediated dilation by reducing Kv channel activity in rat small coronary smooth muscle cells. | American journal of physiology. Heart and circulatory physiology 20030901 |
| Cilostazol prevents tumor necrosis factor-alpha-induced cell death by suppression of phosphatase and tensin homolog deleted from chromosome 10 phosphorylation and activation of Akt/cyclic AMP response element-binding protein phosphorylation. | The Journal of pharmacology and experimental therapeutics 20030901 |
| Modulation of the molecular composition of large conductance, Ca(2+) activated K(+) channels in vascular smooth muscle during hypertension. | The Journal of clinical investigation 20030901 |
| Ionic basis for the regulation of spontaneous excitation in detrusor smooth muscle cells of the guinea-pig urinary bladder. | British journal of pharmacology 20030901 |
| Potassium channels in human umbilical artery cells. | Journal of the Society for Gynecologic Investigation 20030901 |
| Developmental differences in Ca2+-activated K+ channel activity in ovine basilar artery. | American journal of physiology. Heart and circulatory physiology 20030801 |
| Modulation of cholinergic responsiveness through the [beta]-adrenoceptor signal transmission pathway in bovine trachealis. | Journal of applied physiology (Bethesda, Md. : 1985) 20030801 |
| The role of K+ channels in vasorelaxation induced by hypoxia and the modulator effects of lidocaine in the rat carotid artery. | Anesthesia and analgesia 20030801 |
| Active K+ secretion through multiple KCa-type channels and regulation by IKCa channels in rat proximal colon. | American journal of physiology. Gastrointestinal and liver physiology 20030701 |
| Iberiotoxin-induced block of Ca2+-activated K+ channels induces dihydropyridine sensitivity of ACh release from mammalian motor nerve terminals. | The Journal of pharmacology and experimental therapeutics 20030501 |
| Structure, function, and endothelium-derived hyperpolarizing factor in the caudal artery of the SHR and WKY rat. | Arteriosclerosis, thrombosis, and vascular biology 20030501 |
| ATP-sensitive potassium channels mediate dilatation of basilar artery in response to intracellular acidification in vivo. | Stroke 20030501 |
| Calcium influx via L- and N-type calcium channels activates a transient large-conductance Ca2+-activated K+ current in mouse neocortical pyramidal neurons. | The Journal of neuroscience : the official journal of the Society for Neuroscience 20030501 |
| Distinct contributions of small and large conductance Ca2+-activated K+ channels to rat Purkinje neuron function. | The Journal of physiology 20030401 |
| Substance P modulates localized calcium transients and membrane current responses in murine colonic myocytes. | British journal of pharmacology 20030401 |
| Properties of BK(Ca) channels formed by bicistronic expression of hSloalpha and beta1-4 subunits in HEK293 cells. | The Journal of membrane biology 20030315 |
| Vasodilation by the calcium-mobilizing messenger cyclic ADP-ribose. | The Journal of biological chemistry 20030314 |
| Effects of prostaglandin F2alpha on membrane currents in rabbit middle cerebral arterial smooth muscle cells. | American journal of physiology. Heart and circulatory physiology 20030301 |
| Volatile anesthetics regulate pulmonary vascular tension through different potassium channel subtypes in isolated rabbit lungs. | Canadian journal of anaesthesia = Journal canadien d'anesthesie 20030301 |
| Afterhyperpolarization regulates firing rate in neurons of the suprachiasmatic nucleus. | The Journal of neuroscience : the official journal of the Society for Neuroscience 20030301 |
| The large conductance Ca2+-activated potassium channel (pSlo) of the cockroach Periplaneta americana: structure, localization in neurons and electrophysiology. | The European journal of neuroscience 20030301 |
| Functional role of potassium channels in the vasodilating mechanism of levosimendan in porcine isolated coronary artery. | Cardiovascular drugs and therapy 20030301 |
| Hepatocyte growth factor/scatter factor stimulates Ca2+-activated membrane K+ current and migration of MDCK II cells. | The Journal of membrane biology 20030101 |
| Chorion-induced myometrial relaxation is mediated by large-conductance Ca2+-activated K+ channel opening in the guinea pig. | American journal of obstetrics and gynecology 20030101 |
| Pharmacological evidence that tetraethylammonium-sensitive, iberiotoxin-insensitive K+ channels function as a negative feedback element for sympathetic neurotransmission by suppressing omega-conotoxin-GVIA-insensitive Ca2+ channels in the relaxation of rabbit facial vein. | Naunyn-Schmiedeberg's archives of pharmacology 20030101 |
| Stimulatory effects of squamocin, an Annonaceous acetogenin, on Ca(2+)-activated K+ current in cultured smooth muscle cells of human coronary artery. | Chemical research in toxicology 20030101 |
| ACh differentially modulates voltage-gated K channels in glomus cells between DBA/2J and A/J strains of mice. | Advances in experimental medicine and biology 20030101 |
| Modulation of action potential firing by iberiotoxin and NS1619 in rat dorsal root ganglion neurons. | Neuroscience 20030101 |
| 20-Hydroxyeicosatetraenoic acid potentiates contractile activation of canine basilar artery in response to stretch via protein kinase Calpha-mediated inhibition of calcium-activated potassium channel. | Advances in experimental medicine and biology 20030101 |
| G protein activation elicits cerebrovasodilation through interaction with K(ATP) and K(Ca) channels. | Brain research 20021213 |
| Muscarinic M2 receptors inhibit Ca2+-activated K+ channels in rat bladder smooth muscle. | International journal of urology : official journal of the Japanese Urological Association 20021201 |
| Peroxynitrite inhibits Ca2+-activated K+ channel activity in smooth muscle of human coronary arterioles. | Circulation research 20021129 |
| Contribution of the K(Ca) channel to membrane potential and O2 sensitivity is decreased in an ovine PPHN model. | American journal of physiology. Lung cellular and molecular physiology 20021101 |
| Graded response of K+ current, membrane potential, and [Ca2+]i to hypoxia in pulmonary arterial smooth muscle. | American journal of physiology. Lung cellular and molecular physiology 20021101 |
| [BK channels play an important role as a negative feedback mechanism in the regulation of spontaneous rhythmic contraction of urinary bladder smooth muscles]. | Nihon yakurigaku zasshi. Folia pharmacologica Japonica 20021101 |
| Protection of potassium channel inhibitors against hypoxia/reoxygenation-induced death of cultured hippocampal neurons. | Di 1 jun yi da xue xue bao = Academic journal of the first medical college of PLA 20021001 |
| O2 sensing in the human ductus arteriosus: regulation of voltage-gated K+ channels in smooth muscle cells by a mitochondrial redox sensor. | Circulation research 20020920 |
| Glycine 30 in iberiotoxin is a critical determinant of its specificity for maxi-K versus K(V) channels. | FEBS letters 20020911 |
| Ca(2+)-activated potassium (K(Ca)) channel inhibition decreases neuronal activity-blood flow coupling. | Brain research 20020906 |
| EDHF, but not NO or prostaglandins, is critical to evoke a conducted dilation upon ACh in hamster arterioles. | American journal of physiology. Heart and circulatory physiology 20020901 |
| Different mechanism of LPS-induced vasodilation in resistance and conductance arteries from SHR and normotensive rats. | British journal of pharmacology 20020901 |
| K(Ca) channel blockers reveal hyperpolarization and relaxation to K+ in rat isolated mesenteric artery. | American journal of physiology. Heart and circulatory physiology 20020801 |
| Role for endothelium-derived hyperpolarizing factor in vascular tone in rat mesenteric and hindlimb circulations in vivo. | The Journal of physiology 20020801 |
| Chronic carbon monoxide enhanced IbTx-sensitive currents in rat resistance pulmonary artery smooth muscle cells. | American journal of physiology. Lung cellular and molecular physiology 20020701 |
| Trichloroethanol alters action potentials in a subgroup of primary sensory neurones. | Neuroreport 20020507 |
| Vascular smooth muscle cell membrane depolarization after NOS inhibition hypertension. | American journal of physiology. Heart and circulatory physiology 20020501 |
| 14,15-Dihydroxyeicosatrienoic acid relaxes bovine coronary arteries by activation of K(Ca) channels. | American journal of physiology. Heart and circulatory physiology 20020501 |
| Mechanism of cGMP contribution to the vasodilator response to NO in rat middle cerebral arteries. | American journal of physiology. Heart and circulatory physiology 20020501 |
| ATP-stimulated Ca(2+)-activated K(+) efflux pathway and differentiation of human placental cytotrophoblast cells. | American journal of physiology. Regulatory, integrative and comparative physiology 20020401 |
| Ca2+-activated K+ channel blockers induce PKC modulated oscillatory contractions in guinea pig trachea. | Comparative biochemistry and physiology. Toxicology & pharmacology : CBP 20020401 |
| BK channel blockers inhibit potassium-induced proliferation of human astrocytoma cells. | Neuroreport 20020325 |
| Contribution of sarcoplasmic reticulum Ca2+ to the activation of Ca2+ -activated K+ channels in the resting state of arteries from spontaneously hypertensive rats. | Journal of hypertension 20020301 |
| Cloning and characterization of glioma BK, a novel BK channel isoform highly expressed in human glioma cells. | The Journal of neuroscience : the official journal of the Society for Neuroscience 20020301 |
| Endothelium-independent effect of estrogen on Ca(2+)-activated K(+) channels in human coronary artery smooth muscle cells. | Cardiovascular research 20020215 |
| Activation of P2Y receptors stimulates potassium and cation currents in acutely isolated human Müller (glial) cells. | Glia 20020201 |
| Gender-specific K(+)-channel contribution to adenosine-induced relaxation in coronary arterioles. | Journal of applied physiology (Bethesda, Md. : 1985) 20020201 |
| Ion channel diversity in the feline smooth muscle esophagus. | American journal of physiology. Gastrointestinal and liver physiology 20020201 |
| Nitric oxide induces apoptosis by activating K+ channels in pulmonary vascular smooth muscle cells. | American journal of physiology. Heart and circulatory physiology 20020101 |
| Ca(2+) sparks and BK currents in gallbladder myocytes: role in CCK-induced response. | American journal of physiology. Gastrointestinal and liver physiology 20020101 |
| Activity- and target-dependent regulation of large-conductance Ca2+-activated K+ channels in developing chick lumbar motoneurons. | The Journal of neuroscience : the official journal of the Society for Neuroscience 20020101 |
| Lysophospholipids induce membrane hyperpolarization in microglia by activation of IKCa1 Ca(2+)-dependent K(+) channels. | Neuroscience 20020101 |
| BK channel activity determines the extent of cell degeneration after oxygen and glucose deprivation: a study in organotypical hippocampal slice cultures. | Neuroscience 20020101 |
| B16-BL6 melanoma cells release inhibitory factor(s) of active pump activity in isolated lymph vessels. | American journal of physiology. Cell physiology 20011201 |
| Homogeneous segmental profile of carbon monoxide-mediated pulmonary vasodilation in rats. | American journal of physiology. Lung cellular and molecular physiology 20011201 |
| Angiotensin II inhibits and alters kinetics of voltage-gated K(+) channels of rat arterial smooth muscle. | American journal of physiology. Heart and circulatory physiology 20011201 |
| Activation of endothelial cell IK(Ca) with 1-ethyl-2-benzimidazolinone evokes smooth muscle hyperpolarization in rat isolated mesenteric artery. | British journal of pharmacology 20011201 |
| Human myofibroblastic hepatic stellate cells express Ca(2+)-activated K(+) channels that modulate the effects of endothelin-1 and nitric oxide. | Journal of hepatology 20011201 |
| Relaxation and modulation of cyclic AMP production in response to atrial natriuretic peptides in guinea pig tracheal smooth muscle. | European journal of pharmacology 20011102 |
| Chronic estrogen depletion alters adenosine diphosphate-induced pial arteriolar dilation in female rats. | American journal of physiology. Heart and circulatory physiology 20011101 |
| Initial and sustained phases of myogenic response of rat mesenteric small arteries. | American journal of physiology. Heart and circulatory physiology 20011101 |
| Anandamide-induced relaxation of sheep coronary arteries: the role of the vascular endothelium, arachidonic acid metabolites and potassium channels. | British journal of pharmacology 20011101 |
| Effects of different types of K+ channel modulators on the spontaneous myogenic contraction of guinea-pig urinary bladder smooth muscle. | Acta physiologica Scandinavica 20011101 |
| Small-conductance calcium-activated potassium currents in mouse hyperexcitable denervated skeletal muscle. | The Journal of physiology 20011015 |
| Sequential and opposite regulation of two outward K(+) currents by ET-1 in cultured striatal astrocytes. | American journal of physiology. Cell physiology 20011001 |
| Role of sarcoplasmic reticulum in regulation of tonic contraction of rabbit basilar artery. | American journal of physiology. Heart and circulatory physiology 20011001 |
| Rapidly inactivating and non-inactivating calcium-activated potassium currents in frog saccular hair cells. | The Journal of physiology 20011001 |
| Mechanisms of anandamide-induced vasorelaxation in rat isolated coronary arteries. | British journal of pharmacology 20011001 |
| Ethanol reduces excitability in a subgroup of primary sensory neurons by activation of BK(Ca) channels. | The European journal of neuroscience 20011001 |
| Glutamate-mediated extrasynaptic inhibition: direct coupling of NMDA receptors to Ca(2+)-activated K+ channels. | Neuron 20010927 |
| Potassium outward currents in freshly dissociated rabbit corpus cavernosum myocytes. | The Journal of urology 20010901 |
| beta(1)-Subunit of BK channels regulates arterial wall[Ca(2+)] and diameter in mouse cerebral arteries. | Journal of applied physiology (Bethesda, Md. : 1985) 20010901 |
| Decrease in the Ca2+-activated K+ current of pulmonary arterial smooth muscle in pulmonary hypertension rats. | Naunyn-Schmiedeberg's archives of pharmacology 20010901 |
| Suppression of K(+)-induced hyperpolarization by phenylephrine in rat mesenteric artery: relevance to studies of endothelium-derived hyperpolarizing factor. | British journal of pharmacology 20010901 |
| Inhibitory effects of brefeldin A, a membrane transport blocker, on the bradykinin-induced hyperpolarization-mediated relaxation in the porcine coronary artery. | British journal of pharmacology 20010901 |
| NO-induced relaxation of labouring and non-labouring human myometrium is not mediated by cyclic GMP. | British journal of pharmacology 20010901 |
| Paradoxical role of large-conductance calcium-activated K+ (BK) channels in controlling action potential-driven Ca2+ entry in anterior pituitary cells. | The Journal of neuroscience : the official journal of the Society for Neuroscience 20010815 |
| Calcium-sensitive potassium channel inhibitors antagonize genistein- and daidzein-induced arterial relaxation in vitro. | Life sciences 20010810 |
| Further investigations into the endothelium-dependent hyperpolarizing effects of bradykinin and substance P in porcine coronary artery. | British journal of pharmacology 20010801 |
| Inhibition of large-conductance calcium-activated potassium channel by 2-methoxyestradiol in cultured vascular endothelial (HUV-EC-C) cells. | The Journal of membrane biology 20010801 |
| Swelling-induced changes in cytosolic [Ca2++] in insulin-secreting cells: a role in regulatory volume decrease? | Molecular and cellular endocrinology 20010705 |
| Arachidonate dilates basilar artery by lipoxygenase-dependent mechanism and activation of K(+) channels. | American journal of physiology. Regulatory, integrative and comparative physiology 20010701 |
| Relaxation to authentic nitric oxide and SIN-1 in rat isolated mesenteric arteries: variable role for smooth muscle hyperpolarization. | British journal of pharmacology 20010701 |
| Pharmacological evidence for the activation of potassium channels as the mechanism involved in the hypotensive and vasorelaxant effect of dioclein in rat small resistance arteries. | British journal of pharmacology 20010701 |
| Potassium channels regulate tone in rat pulmonary veins. | American journal of physiology. Lung cellular and molecular physiology 20010601 |
| Pulmonary vascular response to normoxia and K(Ca) channel activity is developmentally regulated. | American journal of physiology. Lung cellular and molecular physiology 20010601 |
| EDHF is not K+ but may be due to spread of current from the endothelium in guinea pig arterioles. | American journal of physiology. Heart and circulatory physiology 20010601 |
| Functional receptor-channel coupling compared in contractile and proliferative human vascular smooth muscle. | Journal of cellular physiology 20010501 |
| EETs relax airway smooth muscle via an EpDHF effect: BK(Ca) channel activation and hyperpolarization. | American journal of physiology. Lung cellular and molecular physiology 20010501 |
| [Cellular mechanism of seizure discharge and its normalization by a herbal mixture prescription 'saikokeishito-ka-shakuyaku' (SK)]. | Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 20010501 |
| Capsaicin-induced relaxation in rabbit coronary artery. | The Journal of veterinary medical science 20010501 |
| Activation of K+ channels induces apoptosis in vascular smooth muscle cells. | American journal of physiology. Cell physiology 20010401 |
| Contributions of prostacyclin and nitric oxide to carbon monoxide-induced cerebrovascular dilation in piglets. | American journal of physiology. Heart and circulatory physiology 20010401 |
| Characterization of stretch-activated cation current in coronary smooth muscle cells. | American journal of physiology. Heart and circulatory physiology 20010401 |
| Lysophosphatidylcholine decreases delayed rectifier K+ current in rabbit coronary smooth muscle cells. | The Journal of veterinary medical science 20010401 |
| Differential expression of KV and KCa channels in vascular smooth muscle cells during 1-day culture. | Pflugers Archiv : European journal of physiology 20010401 |
| Modulation of voltage-dependent K+ channel current in vascular smooth muscle cells from rat mesenteric arteries. | The Journal of membrane biology 20010315 |
| Role of K+ channels in N-acetylprocainamide-induced relaxation of bovine tracheal smooth muscle. | European journal of pharmacology 20010309 |
| Voltage dependence of the coupling of Ca(2+) sparks to BK(Ca) channels in urinary bladder smooth muscle. | American journal of physiology. Cell physiology 20010301 |
| Endothelium-independent, ouabain-sensitive relaxation of bovine coronary arteries by EETs. | American journal of physiology. Heart and circulatory physiology 20010301 |
| Inhibition of Na(+)/K(+)-atpase by endothelin-1 in human nonpigmented ciliary epithelial cells. | The Journal of pharmacology and experimental therapeutics 20010301 |
| Mechanism of CGRP-induced relaxation in rat intramural coronary arteries. | British journal of pharmacology 20010301 |
| Functional and molecular characterization of receptor subtypes mediating coronary microvascular dilation to adenosine. | Journal of molecular and cellular cardiology 20010201 |
| Angiotensin II relaxes microvessels via the AT(2) receptor and Ca(2+)-activated K(+) (BK(Ca)) channels. | Hypertension (Dallas, Tex. : 1979) 20010201 |
| Role of calcium-sensitive K(+) channels and nitric oxide in in vivo coronary vasodilation from enhanced perfusion pulsatility. | Circulation 20010102 |
| Muscarinic activation of transient inward current and contraction in canine colon circular smooth muscle cells. | Canadian journal of physiology and pharmacology 20010101 |
| Mechanisms of NO-resistant relaxation induced by acetylcholine in rabbit renal arteries. | The Journal of veterinary medical science 20010101 |
| High-conductance calcium-activated potassium channels; structure, pharmacology, and function. | Journal of bioenergetics and biomembranes 19960601 |
| Mode of action of iberiotoxin, a potent blocker of the large conductance Ca(2+)-activated K+ channel. | Biophysical journal 19920801 |
| Mechanism of iberiotoxin block of the large-conductance calcium-activated potassium channel from bovine aortic smooth muscle. | Biochemistry 19920728 |
| Purification and characterization of a unique, potent, peptidyl probe for the high conductance calcium-activated potassium channel from venom of the scorpion Buthus tamulus. | The Journal of biological chemistry 19900705 |
Related Products
© 2019 Angene International Limited. All rights Reserved.