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129-81-7

129-81-7 | 3H-Pyrazol-3-one, 1,2-dihydro-4-iodo-1,5-dimethyl-2-phenyl-

CAS No: 129-81-7 Catalog No: AG000YR7 MDL No:

Product Description

Catalog Number:
AG000YR7
Chemical Name:
3H-Pyrazol-3-one, 1,2-dihydro-4-iodo-1,5-dimethyl-2-phenyl-
CAS Number:
129-81-7
Molecular Formula:
C11H11IN2O
Molecular Weight:
314.1223
IUPAC Name:
4-iodo-1,5-dimethyl-2-phenylpyrazol-3-one
InChI:
InChI=1S/C11H11IN2O/c1-8-10(12)11(15)14(13(8)2)9-6-4-3-5-7-9/h3-7H,1-2H3
InChI Key:
ZZOBLCHCPLOXCE-UHFFFAOYSA-N
SMILES:
Ic1c(C)n(n(c1=O)c1ccccc1)C
EC Number:
204-966-6
UNII:
V30V6H1QX4

Properties

Complexity:
308  
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
0
Defined Bond Stereocenter Count:
0
Exact Mass:
313.992g/mol
Formal Charge:
0
Heavy Atom Count:
15  
Hydrogen Bond Acceptor Count:
2  
Hydrogen Bond Donor Count:
0
Isotope Atom Count:
0
Molecular Weight:
314.126g/mol
Monoisotopic Mass:
313.992g/mol
Rotatable Bond Count:
1  
Topological Polar Surface Area:
23.6A^2
Undefined Atom Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
XLogP3:
1.3  

Literature

Title Journal
Kallikrein gene transfer induces angiogenesis and further improves regional cerebral blood flow in the early period after cerebral ischemia/reperfusion in rats. CNS neuroscience & therapeutics 20120501
A novel intravital method to evaluate cerebral vasospasm in rat models of subarachnoid hemorrhage: a study with synchrotron radiation angiography. PloS one 20120101
Aggravation of polypoidal choroidal vasculopathy after cataract surgery. Indian journal of ophthalmology 20120101
[Determination of the optimal ROI setting position of the input function for the ⁹⁹mTc-ethyl cysteinate dimmer brain uptake ratio method]. Nihon Hoshasen Gijutsu Gakkai zasshi 20120101
Effects of GABA(A) receptor blockade on regional cerebral blood flow and blood-brain barrier disruption in focal cerebral ischemia. Journal of the neurological sciences 20110215
Mapping functional brain activation using [14C]-iodoantipyrine in male serotonin transporter knockout mice. PloS one 20110101
[Use of interferon inducers for pharmacological correction of cytokine disturbances in patients with recurrent genital herpes]. Eksperimental'naia i klinicheskaia farmakologiia 20100801
Animal models and biomarkers of neuropathy in diabetic rodents. Indian journal of pharmacology 20100601
The effects of isoflurane pretreatment on cerebral blood flow, capillary permeability, and oxygen consumption in focal cerebral ischemia in rats. Anesthesia and analgesia 20100501
Mapping selective neuronal loss and microglial activation in the salvaged neocortical penumbra in the rat. NeuroImage 20100101
Fenofibrate improves cerebral blood flow after middle cerebral artery occlusion in mice. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 20100101
Effects of fentanyl pretreatment on regional cerebral blood flow in focal cerebral ischemia in rats. Pharmacology 20100101
[Use of the interferon inductor iodantipirine in the prevention and treatment of some viral infections]. Meditsinskaia parazitologiia i parazitarnye bolezni 20100101
Quantitative imaging of coronary blood flow. Nano reviews 20100101
Increase in tumour permeability following TGF-beta type I receptor-inhibitor treatment observed by dynamic contrast-enhanced MRI. British journal of cancer 20091201
Sex differences in functional brain activation during noxious visceral stimulation in rats. Pain 20090901
Quantitative estimation of tissue blood flow rate. Methods in molecular biology (Clifton, N.J.) 20090101
Why amphibians are more sensitive than mammals to xenobiotics. PloS one 20090101
Changes in regional brain perfusion during functional brain activation: comparison of [(64)Cu]-PTSM with [(14)C]-Iodoantipyrine. Brain research 20081009
Soluble epoxide hydrolase gene deletion is protective against experimental cerebral ischemia. Stroke 20080701
Changes of cerebral blood flow during the secondary expansion of a cortical contusion assessed by 14C-iodoantipyrine autoradiography in mice using a non-invasive protocol. Journal of neurotrauma 20080701
Flattened cortical maps of cerebral function in the rat: a region-of-interest approach to data sampling, analysis and display. Neuroscience letters 20080328
A flow sensitive alternating inversion recovery (FAIR)-MRI protocol to measure hemispheric cerebral blood flow in a mouse stroke model. Experimental neurology 20080301
Wide therapeutic time window for Rho-kinase inhibition therapy in ischemic brain damage in a rat cerebral thrombosis model. Brain research 20080208
The effect of isovolemic hemodilution with oxycyte, a perfluorocarbon emulsion, on cerebral blood flow in rats. PloS one 20080101
Reorganization of functional brain maps after exercise training: Importance of cerebellar-thalamic-cortical pathway. Brain research 20071212
Soluble epoxide hydrolase: a novel therapeutic target in stroke. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 20071201
[Epileptogenic and non-epileptogenic zones: blood flow studies of temporo-limbic seizures]. Revue neurologique 20071201
Direct comparison study between FDG-PET and IMP-SPECT for diagnosing Alzheimer's disease using 3D-SSP analysis in the same patients. Radiation medicine 20070701
Cortical contusion induces trans-hemispheric reorganization of blood flow maps. Brain research 20070413
Persistent cerebrovascular effects of MDMA and acute responses to the drug. The European journal of neuroscience 20060701
Multiple retinal hemorrhage following anterior chamber paracentesis in uveitic glaucoma. Korean journal of ophthalmology : KJO 20060601
Optimal window for ictal blood flow mapping. Insight from the study of discrete temporo-limbic seizures in rats. Epilepsy research 20060501
Effects of estrogen on platelet reactivity after transient forebrain ischemia in rats. Biological research for nursing 20051001
Time course and mapping of cerebral perfusion during amygdala secondarily generalized seizures. Epilepsia 20050801
The endothelin B (ETB) receptor agonist IRL 1620 is highly vasoconstrictive in two syngeneic rat tumour lines: potential for selective tumour blood flow modification. British journal of cancer 20050711
Restoration of cerebral vasoreactivity by an L-type calcium channel blocker following fluid percussion brain injury. Journal of neurotrauma 20050701
Role of nitric oxide in cerebral blood flow changes during kainate seizures in mice: genetic and pharmacological approaches. Neurobiology of disease 20050301
Computational study on use of single-point analysis method for quantitating local cerebral blood flow in mice. Advances in experimental medicine and biology 20050101
Relationship between flow-metabolism uncoupling and evolving axonal injury after experimental traumatic brain injury. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 20040901
Evolution of diaschisis in a focal stroke model. Stroke 20040301
Regional heterogeneity of cerebral blood flow response to graded pressure-controlled hemorrhage. The Journal of trauma 20040301
Extension of cerebral hypoperfusion and ischaemic pathology beyond MCA territory after intraluminal filament occlusion in C57Bl/6J mice. Brain research 20040130
Activation of cerebral cortex during acoustic challenge or acute foot-shock in freely moving, nontethered rats. Neuroscience letters 20040102
Effects of chronic isovolaemic haemodilution on regional cerebral blood flow in conscious rats. European journal of anaesthesiology 20040101
Inhibition of [18F]FP-TZTP binding by loading doses of muscarinic agonists P-TZTP or FP-TZTP in vivo is not due to agonist-induced reduction in cerebral blood flow. Synapse (New York, N.Y.) 20031101
Functional brain mapping in freely moving rats during treadmill walking. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 20030801
Effects of tin-protoporphyrin IX on blood flow in a rat tumor model. Experimental biology and medicine (Maywood, N.J.) 20030501
Direct comparison of local cerebral blood flow rates measured by MRI arterial spin-tagging and quantitative autoradiography in a rat model of experimental cerebral ischemia. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 20030201
Cortical spreading depression causes a long-lasting decrease in cerebral blood flow and induces tolerance to permanent focal ischemia in rat brain. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 20030101
Cerebral hypoperfusion and delayed hippocampal response after induction of adult kaolin hydrocephalus. Stroke 20030101
The vascular response of tumor and normal tissues in the rat to the vascular targeting agent, combretastatin A-4-phosphate, at clinically relevant doses. International journal of oncology 20021001
Early effects of acid-base management during hypothermia on cerebral infarct volume, edema, and cerebral blood flow in acute focal cerebral ischemia in rats. Anesthesiology 20021001
Dynamic variations of local cerebral blood flow in maximal electroshock seizures in the rat. Epilepsia 20021001
Progesterone administration during reperfusion, but not preischemia alone, reduces injury in ovariectomized rats. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 20021001
Effect of mild hypothermia on energy state recovery following transient forebrain ischemia in the gerbil. Experimental brain research 20020701
Neuroprotection and P450 2C11 upregulation after experimental transient ischemic attack. Stroke 20020601
Evaluation of the anti-vascular effects of combretastatin in rodent tumours by dynamic contrast enhanced MRI. NMR in biomedicine 20020401
Effect of manipulation of primary tumour vascularity on metastasis in an adenocarcinoma model. British journal of cancer 20020107
Imaging of ischemic but viable myocardium using a new 18F-labeled 2-nitroimidazole analog, 18F-FRP170. Journal of nuclear medicine : official publication, Society of Nuclear Medicine 20020101
[Clinical response to combined treatment with reaferon and iodantipirin in patients with chronic HCV- and HBV-infection]. Klinicheskaia meditsina 20020101
Effects of recombinant tissue plasminogen activator after intraluminal thread occlusion in mice: role of hemodynamic alterations. Stroke 20011101
Quantitative imaging of tumour blood flow by contrast-enhanced magnetic resonance imaging. British journal of cancer 20011101
Phosphorylation of cyclic adenosine monophosphate response element binding protein in oligodendrocytes in the corpus callosum after focal cerebral ischemia in the rat. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 20011001
An autoradiographic study of regional blood flow distribution in the rat kidney during ureteric obstruction--the role of vasoactive compounds. BJU international 20010801
Lack of hypercapnic increase in cerebral blood flow at high blood viscosity in conscious blood-exchanged rats. Anesthesiology 20010801
Dissociation of brain edema induced by cold injury in rat model: MR imaging and perfusion studies with 14C-iodo-antipyrine. Annals of nuclear medicine 20010801
Simultaneous measurement of cerebral blood flow and mRNA signals: pixel-based inter-modality correlational analysis. Journal of neuroscience methods 20010730
Uncoupling of cerebral blood flow and metabolism after cerebral contusion in the rat. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 20010701
Oxygen delivery at high blood viscosity and decreased arterial oxygen content to brains of conscious rats. American journal of physiology. Heart and circulatory physiology 20010601
Quantitative analysis of rat inner ear blood flow using the iodo[(14)C]antipyrine technique. Hearing research 20010301
Comparison of cell inactivation by Auger electrons using the two reagents 4-[123I]iodoantipyrine and [123I]NaI. Radiation and environmental biophysics 20010301
Experimental stroke in the female diabetic, db/db, mouse. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 20010101
[Comparative in vitro study of the effectiveness of various immunomodulating substances in tick-borne encephalitis]. Voprosy virusologii 20010101
[Changes in the immune status parameters and their correction in various forms of tick-borne encephalitis]. Antibiotiki i khimioterapiia = Antibiotics and chemoterapy [sic] 20010101

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