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12778-32-4

12778-32-4 | β-Bungarotoxin

CAS No: 12778-32-4 Catalog No: AG000XEG MDL No:

Product Description

Catalog Number:
AG000XEG
Chemical Name:
β-Bungarotoxin
CAS Number:
12778-32-4
Molecular Formula:
C50H70O14
Molecular Weight:
895.0824
IUPAC Name:
2-[[(1R,3S,5R,7S,9R,11S,12S,14S,16R,18S,20R,24S,26R,28S,30R,31R,33S,35R,37S,42R,44S,46R,48S)-12-hydroxy-1,3,11,24,31,41,44-heptamethyl-39-oxo-2,6,10,15,19,25,29,34,38,43,47-undecaoxaundecacyclo[26.22.0.03,26.05,24.07,20.09,18.011,16.030,48.033,46.035,44.037,42]pentaconta-21,40-dien-14-yl]methyl]prop-2-enal
InChI:
InChI=1S/C50H70O14/c1-25(24-51)14-28-17-37(52)50(8)41(54-28)19-33-34(61-50)18-32-29(55-33)10-9-12-46(4)42(58-32)23-49(7)40(62-46)21-39-47(5,64-49)13-11-30-44(60-39)26(2)15-31-36(56-30)22-48(6)38(57-31)20-35-45(63-48)27(3)16-43(53)59-35/h9-10,16,24,26,28-42,44-45,52H,1,11-15,17-23H2,2-8H3/t26-,28+,29-,30+,31+,32+,33+,34-,35+,36-,37+,38-,39+,40-,41-,42-,44-,45-,46+,47-,48+,49+,50+/m1/s1
InChI Key:
LYTCVQQGCSNFJU-PJLYXUTNSA-N
SMILES:
O=CC(=C)C[C@H]1C[C@H](O)[C@]2([C@H](O1)C[C@H]1[C@H](O2)C[C@H]2[C@H](O1)C=CC[C@]1([C@H](O2)C[C@]2(C)O[C@]3(C)CC[C@H]4[C@H](O[C@H]3C[C@H]2O1)[C@H](C)C[C@H]1[C@H](O4)C[C@]2(C)O[C@@H]3C(=CC(=O)O[C@H]3C[C@H]2O1)C)C)C
EC Number:
235-821-5

Properties

Complexity:
1940  
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
23  
Defined Bond Stereocenter Count:
0
Exact Mass:
894.477g/mol
Formal Charge:
0
Heavy Atom Count:
64  
Hydrogen Bond Acceptor Count:
14  
Hydrogen Bond Donor Count:
1  
Isotope Atom Count:
0
Molecular Weight:
895.096g/mol
Monoisotopic Mass:
894.477g/mol
Rotatable Bond Count:
3  
Topological Polar Surface Area:
156A^2
Undefined Atom Stereocenter Count:
0
Undefined Bond Stereocenter Count:
1  
XLogP3:
3.7  

Literature

Title Journal
Cigarette smoke extract interferes with placenta macrophage functions: A new mechanism to compromise placenta functions? Reproductive toxicology (Elmsford, N.Y.) 20180601
Crystal structures of free and antagonist-bound states of human α9 nicotinic receptor extracellular domain. Nature structural & molecular biology 20141101
Quantitative changes of nicotinic receptors in the hippocampus of dystrophin-deficient mice. Brain research 20121105
Nicotine stimulates proliferation and inhibits apoptosis in colon cancer cell lines through activation of survival pathways. The Journal of surgical research 20121101
Diurnal variation in nicotine sensitivity in mice: role of genetic background and melatonin. Neuropharmacology 20121101
Type I and II positive allosteric modulators differentially modulate agonist-induced up-regulation of α7 nicotinic acetylcholine receptors. Journal of neurochemistry 20121001
Near-complete adaptation of the PRiMA knockout to the lack of central acetylcholinesterase. Journal of neurochemistry 20120901
Involvement of cholinergic mechanisms in the behavioral effects of dietary fat consumption. Brain research 20120827
Differences in sensitivity to rocuronium among orbicularis oris muscles innervated by normal or damaged facial nerves and gastrocnemius muscle innervated by somatic nerve in rats: combined morphological and functional analyses. The Laryngoscope 20120801
In utero nicotine exposure promotes M2 activation in neonatal mouse alveolar macrophages. Pediatric research 20120801
Lipopolysaccharide upregulates α7 acetylcholine receptors: stimulation with GTS-21 mitigates growth arrest of macrophages and improves survival in burned mice. Shock (Augusta, Ga.) 20120801
Highly fatal fast-channel syndrome caused by AChR ε subunit mutation at the agonist binding site. Neurology 20120731
Myasthenic syndrome AChRα C-loop mutant disrupts initiation of channel gating. The Journal of clinical investigation 20120702
Touch responsiveness in zebrafish requires voltage-gated calcium channel 2.1b. Journal of neurophysiology 20120701
M2 muscarinic acetylcholine receptors regulate long-term potentiation at hippocampal CA3 pyramidal cell synapses in an input-specific fashion. Journal of neurophysiology 20120701
A novel α-conotoxin MII-sensitive nicotinic acetylcholine receptor modulates [(3) H]-GABA release in the superficial layers of the mouse superior colliculus. Journal of neurochemistry 20120701
Mechanism of YB-1-mediated translational induction of GluR2 mRNA in response to neural activity through nAChR. Biochimica et biophysica acta 20120701
Analysis of spontaneous and nerve-evoked calcium transients in intact extraocular muscles in vitro. Experimental eye research 20120701
Characterization of the spinal nucleus of the bulbocavernosus neuromuscular system in male mice lacking androgen receptor in the nervous system. Endocrinology 20120701
Nornicotine application on cockroach dorsal unpaired median neurons induces two distinct ionic currents: implications of different nicotinic acetylcholine receptors. Neuroscience letters 20120614
The effect of nicotine on anti-vascular endothelial growth factor therapy in a mouse model of neovascular age-related macular degeneration. Retina (Philadelphia, Pa.) 20120601
Neuroprotection by nicotine against colchicine-induced apoptosis is mediated by PI3-kinase--Akt pathways. The International journal of neuroscience 20120601
Protective effect of PNU-120596, a selective alpha7 nicotinic acetylcholine receptor-positive allosteric modulator, on myocardial ischemia-reperfusion injury in rats. Journal of cardiovascular pharmacology 20120601
Neural regulation of esophageal striated muscle in the house musk shrew (Suncus murinus). Autonomic neuroscience : basic & clinical 20120521
NNK promotes migration and invasion of lung cancer cells through activation of c-Src/PKCι/FAK loop. Cancer letters 20120501
Transmembrane potential polarization, calcium influx, and receptor conformational state modulate the sensitivity of the imidacloprid-insensitive neuronal insect nicotinic acetylcholine receptor to neonicotinoid insecticides. The Journal of pharmacology and experimental therapeutics 20120501
The sea urchin, Paracentrotus lividus, as a model to investigate the onset of molecules immunologically related to the α-7 subunit of nicotinic receptors during embryonic and larval development. Current drug targets 20120501
Regulation of GABAergic inputs to CA1 pyramidal neurons by nicotinic receptors and kynurenic acid. The Journal of pharmacology and experimental therapeutics 20120501
Nicotinic acetylcholine receptor α7 and β4 subunits contribute nicotine-induced apoptosis in periodontal ligament stem cells. Molecules and cells 20120430
Acute severe animal model of anti-muscle-specific kinase myasthenia: combined postsynaptic and presynaptic changes. Archives of neurology 20120401
A novel congenital myasthenic syndrome due to decreased acetylcholine receptor ion-channel conductance. Brain : a journal of neurology 20120401
Osteopontin is an alpha motor neuron marker in the mouse spinal cord. Journal of neuroscience research 20120401
Anti-LRP4 autoantibodies in AChR- and MuSK-antibody-negative myasthenia gravis. Journal of neurology 20120301
Calcium dependence of damage to mouse motor nerve terminals following oxygen/glucose deprivation. Experimental neurology 20120301
A possible role of the cholinergic and purinergic receptor interaction in the regulation of the rat urinary bladder function. Journal of muscle research and cell motility 20120301
Tryptophan scanning mutagenesis reveals distortions in the helical structure of the δM4 transmembrane domain of the Torpedo californica nicotinic acetylcholine receptor. Channels (Austin, Tex.) 20120301
Nicotine-mediated induction of E-selectin in aortic endothelial cells requires Src kinase and E2F1 transcriptional activity. Biochemical and biophysical research communications 20120203
Pharmacological characterization of native α7 nicotinic ACh receptors and their contribution to depolarization-elicited exocytosis in human chromaffin cells. British journal of pharmacology 20120201
Up-regulation of the neuronal nicotinic receptor α7 by HIV glycoprotein 120: potential implications for HIV-associated neurocognitive disorder. The Journal of biological chemistry 20120127
Differential protection of neuromuscular sensory and motor axons and their endings in Wld(S) mutant mice. Neuroscience 20120103
Electroacupuncture pretreatment attenuates cerebral ischemic injury through α7 nicotinic acetylcholine receptor-mediated inhibition of high-mobility group box 1 release in rats. Journal of neuroinflammation 20120101
Nicotine-like effects of the neonicotinoid insecticides acetamiprid and imidacloprid on cerebellar neurons from neonatal rats. PloS one 20120101
Indomethacin activates protein kinase C and potentiates α7 ACh receptor responses. Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 20120101
Modulation of TTX-sensitive voltage-dependent Na+ channels by β-bungarotoxin in rat cerebellar neurons. BMC neuroscience 20120101
Effects of nicotine on PTHrP and PTHrP receptor expression in rat coronary endothelial cells. Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 20120101
α7 nicotinic acetylcholine receptor-mediated neuroprotection against dopaminergic neuron loss in an MPTP mouse model via inhibition of astrocyte activation. Journal of neuroinflammation 20120101
The Drosophila nicotinic acetylcholine receptor subunits Dα5 and Dα7 form functional homomeric and heteromeric ion channels. BMC neuroscience 20120101
Molecular dissection of Cl--selective Cys-loop receptor points to components that are dispensable or essential for channel activity. The Journal of biological chemistry 20111223
Strain-dependent urethral response. Neurourology and urodynamics 20111101
Amyotrophic lateral sclerosis-immunoglobulins selectively interact with neuromuscular junctions expressing P/Q-type calcium channels. Journal of neurochemistry 20111101
Nicotinic acetylcholine receptor stability at the NMJ deficient in α-syntrophin in vivo. The Journal of neuroscience : the official journal of the Society for Neuroscience 20111026
Changes in aging mouse neuromuscular junctions are explained by degeneration and regeneration of muscle fiber segments at the synapse. The Journal of neuroscience : the official journal of the Society for Neuroscience 20111019
Onset of cholinergic efferent synaptic function in sensory hair cells of the rat cochlea. The Journal of neuroscience : the official journal of the Society for Neuroscience 20111019
The chimeric gene CHRFAM7A, a partial duplication of the CHRNA7 gene, is a dominant negative regulator of α7*nAChR function. Biochemical pharmacology 20111015
Substitutions of amino acids in the pore domain of homomeric α7 nicotinic receptors for analogous residues present in heteromeric receptors modify gating, rectification and binding properties. Journal of neurochemistry 20111001
Decreased α4β2 nicotinic receptor number in the absence of mRNA changes suggests post-transcriptional regulation in the spontaneously hypertensive rat model of ADHD. Journal of neurochemistry 20111001
Identification of a cholinergic modulatory and rhythmogenic mechanism within the lamprey respiratory network. The Journal of neuroscience : the official journal of the Society for Neuroscience 20110914
A role of the sulfonylurea receptor 1 in endocytic trafficking of ATP-sensitive potassium channels. Traffic (Copenhagen, Denmark) 20110901
An absolute requirement for Pax7-positive satellite cells in acute injury-induced skeletal muscle regeneration. Development (Cambridge, England) 20110901
Single-pixel optical fluctuation analysis of calcium channel function in active zones of motor nerve terminals. The Journal of neuroscience : the official journal of the Society for Neuroscience 20110803
Evidence for operation of nicotinic and muscarinic acetylcholine receptor-dependent survival pathways in human coronary artery endothelial cells. Journal of cellular biochemistry 20110801
Solid-phase receptor-based assay for the detection of cyclic imines by chemiluminescence, fluorescence, or colorimetry. Analytical chemistry 20110801
Nicotine improves the functional activity of late endothelial progenitor cells via nicotinic acetylcholine receptors. Biochemistry and cell biology = Biochimie et biologie cellulaire 20110801
Gamma-aminobutyric acid type B (GABA(B)) receptor internalization is regulated by the R2 subunit. The Journal of biological chemistry 20110708
Thirdhand smoke: a new dimension to the effects of cigarette smoke on the developing lung. American journal of physiology. Lung cellular and molecular physiology 20110701
Tetanic failure due to decreased endogenous adenosine A(2A) tonus operating neuronal Ca(v) 1 (L-type) influx in Myasthenia gravis. Journal of neurochemistry 20110601
An extracellular RRR motif flanking the M1 transmembrane domain governs the biogenesis of homomeric neuronal nicotinic acetylcholine receptors. FEBS letters 20110420
Human platelets express functional alpha7-nicotinic acetylcholine receptors. Arteriosclerosis, thrombosis, and vascular biology 20110401
NMR structure and action on nicotinic acetylcholine receptors of water-soluble domain of human LYNX1. The Journal of biological chemistry 20110325
Recombinant expression of the AChR-alpha1 subunit for the detection of conformation-dependent epitopes in Myasthenia Gravis. Neuromuscular disorders : NMD 20110301
Functional nicotinic acetylcholine receptors containing α6 subunits are on GABAergic neuronal boutons adherent to ventral tegmental area dopamine neurons. The Journal of neuroscience : the official journal of the Society for Neuroscience 20110216
Glial cell line-derived neurotrophic factor protein content in rat skeletal muscle is altered by increased physical activity in vivo and in vitro. Neuroscience 20110203
Fast synaptic transmission in the goldfish CNS mediated by multiple nicotinic receptors. The Journal of physiology 20110201
Function of partially duplicated human α77 nicotinic receptor subunit CHRFAM7A gene: potential implications for the cholinergic anti-inflammatory response. The Journal of biological chemistry 20110107
Distinct localization of collagen Q and PRiMA forms of acetylcholinesterase at the neuromuscular junction. Molecular and cellular neurosciences 20110101
Differential sensitivity of Ctenocephalides felis and Drosophila melanogaster nicotinic acetylcholine receptor α1 and α2 subunits in recombinant hybrid receptors to nicotinoids and neonicotinoid insecticides. Insect biochemistry and molecular biology 20110101
A computational investigation on the role of glycosylation in the binding of alpha1 nicotinic acetylcholine receptor with two alpha-neurotoxins. Proteins 20110101
Changes in cationic selectivity of the nicotinic channel at the rat ganglionic synapse: a role for chloride ions? PloS one 20110101
Visualization, characterization and modulation of calcium signaling during the development of slow muscle cells in intact zebrafish embryos. The International journal of developmental biology 20110101
The presence and origin of autoantibodies against α4 and α7 nicotinic acetylcholine receptors in the human blood: possible relevance to Alzheimer's pathology. Journal of Alzheimer's disease : JAD 20110101
A novel labeling approach identifies three stability levels of acetylcholine receptors in the mouse neuromuscular junction in vivo. PloS one 20110101
Nicotine reduces TNF-α expression through a α7 nAChR/MyD88/NF-ĸB pathway in HBE16 airway epithelial cells. Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 20110101
Rapid internalization of the oncogenic K+ channel K(V)10.1. PloS one 20110101
Design of new α-conotoxins: from computer modeling to synthesis of potent cholinergic compounds. Marine drugs 20110101
Hippocampal α7 nicotinic acetylcholine receptor levels in patients with schizophrenia, bipolar disorder, or major depressive disorder. Bipolar disorders 20110101
Microanatomy of adult zebrafish extraocular muscles. PloS one 20110101
Neuroprotective effect of nicotine against kainic acid excitotoxicity is associated with alpha-bungarotoxin insensitive receptors subtype of nAChRs. Neuro endocrinology letters 20110101
[Bacterial expression of water-soluble domain of Lynx1, endogenic neuromodulator of human nicotinic acetylcholine receptors]. Bioorganicheskaia khimiia 20110101
The interaction between tropomyosin-related kinase B receptors and presynaptic muscarinic receptors modulates transmitter release in adult rodent motor nerve terminals. The Journal of neuroscience : the official journal of the Society for Neuroscience 20101208
Stimulation of α7 nicotinic acetylcholine receptor by nicotine increases suppressive capacity of naturally occurring CD4+CD25+ regulatory T cells in mice in vitro. The Journal of pharmacology and experimental therapeutics 20101201
Counting bungarotoxin binding sites of nicotinic acetylcholine receptors in mammalian cells with high signal/noise ratios. Biophysical journal 20101117
Pharmacological characterization of [(125)I]CHIBA-1006 binding, a new radioligand for α7 nicotinic acetylcholine receptors, to rat brain membranes. Brain research 20101111
Hyponatraemia, rhabdomyolysis, alterations in blood pressure and persistent mydriasis in patients envenomed by Malayan kraits (Bungarus candidus) in southern Viet Nam. Toxicon : official journal of the International Society on Toxinology 20101101
Activity-dependent regulation of the binomial parameters p and n at the mouse neuromuscular junction in vivo. Journal of neurophysiology 20101101
The greater black krait (Bungarus niger), a newly recognized cause of neuro-myotoxic snake bite envenoming in Bangladesh. Brain : a journal of neurology 20101101
Cotinine exposure increases Fallopian tube PROKR1 expression via nicotinic AChRalpha-7: a potential mechanism explaining the link between smoking and tubal ectopic pregnancy. The American journal of pathology 20101101
Olfactory discrimination varies in mice with different levels of α7-nicotinic acetylcholine receptor expression. Brain research 20101028
In vitro binding characteristics of [3H]AZ11637326, a novel alpha7-selective neuronal nicotinic receptor agonist radioligand. European journal of pharmacology 20101025
Age-related motor neuron degeneration in DNA repair-deficient Ercc1 mice. Acta neuropathologica 20101001
Cholinergic activation of hematopoietic stem cells: role in tobacco-related disease? Vascular medicine (London, England) 20101001
An imaging assay to analyze primary neurons for cellular neurotoxicity. Journal of neuroscience methods 20100930
Functional connectivity and selective odor responses of excitatory local interneurons in Drosophila antennal lobe. Neuron 20100923
The frequency-dependence of the nicotine-induced inhibition of dopamine is controlled by the α7 nicotinic receptor. Journal of neurochemistry 20100901
Identification of neuromuscular junctions by correlative confocal and transmission electron microscopy. Journal of neuroscience methods 20100830
Characterization of [(3)H]CHIBA-1001 binding to alpha7 nicotinic acetylcholine receptors in the brain from rat, monkey, and human. Brain research 20100812
Detection of 13,19-didesmethyl C spirolide by fluorescence polarization using Torpedo electrocyte membranes. Analytical biochemistry 20100801
Repeated administration of alpha7 nicotinic acetylcholine receptor (nAChR) agonists, but not positive allosteric modulators, increases alpha7 nAChR levels in the brain. Journal of neurochemistry 20100801
Ric-3 promotes alpha7 nicotinic receptor assembly and trafficking through the ER subcompartment of dendrites. The Journal of neuroscience : the official journal of the Society for Neuroscience 20100728
Trypanosoma evansi: pharmacological evidence of a nicotinic acetylcholine receptor. Experimental parasitology 20100601
Thyroid hormone enhances transected axonal regeneration and muscle reinnervation following rat sciatic nerve injury. Journal of neuroscience research 20100601
Stoichiometry of expressed alpha(4)beta(2)delta gamma-aminobutyric acid type A receptors depends on the ratio of subunit cDNA transfected. The Journal of biological chemistry 20100507
Kinetics of agonist-induced intrinsic fluorescence changes in the Torpedo acetylcholine receptor. Journal of biochemistry 20100501
Central cholinesterase inhibition enhances glutamatergic synaptic transmission. Journal of neurophysiology 20100401
In vivo long-term synaptic plasticity of glial cells. The Journal of physiology 20100401
Role of the vagus nerve on the development of postoperative ileus. Langenbeck's archives of surgery 20100401
Dynamics of the rapsyn scaffolding protein at the neuromuscular junction of live mice. The Journal of neuroscience : the official journal of the Society for Neuroscience 20100113
Assessing the effects of the neonicotinoid insecticide imidacloprid in the cholinergic synapses of the stellate cells of the mouse cochlear nucleus using whole-cell patch-clamp recording. Neurotoxicology 20100101
K(V)4.2 channels tagged in the S1-S2 loop for alpha-bungarotoxin binding provide a new tool for studies of channel expression and localization. Channels (Austin, Tex.) 20100101
Transcriptomic analysis of the venom gland of the red-headed krait (Bungarus flaviceps) using expressed sequence tags. BMC molecular biology 20100101
The effect of nicotine on the production of soluble fms-like tyrosine kinase-1 and soluble endoglin in human umbilical vein endothelial cells and trophoblasts. Acta obstetricia et gynecologica Scandinavica 20100101
Vaccination with peptide 173-193 of acetylcholine receptor α7-subunit prevents memory loss in olfactory bulbectomized mice. Journal of Alzheimer's disease : JAD 20100101
Single particle tracking of alpha7 nicotinic AChR in hippocampal neurons reveals regulated confinement at glutamatergic and GABAergic perisynaptic sites. PloS one 20100101
Effect of huprine X on β-amyloid, synaptophysin and α7 neuronal nicotinic acetylcholine receptors in the brain of 3xTg-AD and APPswe transgenic mice. Neuro-degenerative diseases 20100101
Role of neostigmine and polyvalent antivenom in Indian common krait (Bungarus caeruleus) bite. Journal of infection and public health 20100101
Auto-positive feedback regulation for nicotinic acetylcholine receptors by protein kinase C activation. Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 20100101
Engineering neuronal nicotinic acetylcholine receptors with functional sensitivity to alpha-bungarotoxin: a novel alpha3-knock-in mouse. The European journal of neuroscience 20091203
Ultrastructural and molecular biologic comparison of classic proprioceptors and palisade endings in sheep extraocular muscles. Investigative ophthalmology & visual science 20091201
Second-by-second analysis of alpha 7 nicotine receptor regulation of glutamate release in the prefrontal cortex of awake rats. Synapse (New York, N.Y.) 20091201
Ondansetron results in improved auditory gating in DBA/2 mice through a cholinergic mechanism. Brain research 20091201
Computational modeling study of human nicotinic acetylcholine receptor for developing new drugs in the treatment of alcoholism. Interdisciplinary sciences, computational life sciences 20091201
Isolation, complete amino acid sequence and characterization of a previously unreported post-synaptic neurotoxin - AlphaN3, from the venom of Bungarus candidus. Biochemical and biophysical research communications 20091113
Cellular distribution of the nicotinic acetylcholine receptor alpha7 subunit in rat hippocampus. Neuroscience research 20091101
Interaction of alpha-conotoxin ImII and its analogs with nicotinic receptors and acetylcholine-binding proteins: additional binding sites on Torpedo receptor. Journal of neurochemistry 20091101
{alpha}7 nicotinic acetylcholine receptor regulates airway epithelium differentiation by controlling basal cell proliferation. The American journal of pathology 20091101
Control of lung epithelial growth by a nicotinic acetylcholine receptor: the other side of the coin. The American journal of pathology 20091101
Prenatal nicotine exposure alters medullary nicotinic and AMPA-mediated control of respiratory frequency in vitro. Respiratory physiology & neurobiology 20091031
Hydrophobic photolabeling studies identify the lipid-protein interface of the 5-HT3A receptor. Biochemistry 20091006
Effect of homologous serotonin receptor loop substitutions on the heterologous expression in Pichia of a chimeric acetylcholine-binding protein with alpha-bungarotoxin-binding activity. Protein expression and purification 20091001
The neurotoxicological effects of mastoparan Polybia-MPII at the murine neuromuscular junction: an ultrastructural and immunocytochemical study. Histochemistry and cell biology 20091001
A novel fluorescent alpha-conotoxin for the study of alpha7 nicotinic acetylcholine receptors. Journal of neurochemistry 20091001
Bacterial production and refolding from inclusion bodies of a 'weak' toxin, a disulfide rich protein. Biochemistry. Biokhimiia 20091001
Mutations of cytosolic loop residues impair assembly and maturation of alpha7 nicotinic acetylcholine receptors. Journal of neurochemistry 20090901
Development of microglia in the chick embryo spinal cord: implications in the regulation of motoneuronal survival and death. Journal of neuroscience research 20090815
Nicotine stimulates PPARbeta/delta expression in human lung carcinoma cells through activation of PI3K/mTOR and suppression of AP-2alpha. Cancer research 20090815
Inhibition of non-neuronal alpha7-nicotinic receptor reduces tumorigenicity in A549 NSCLC xenografts. International journal of cancer 20090701
Silencing rapsyn in vivo decreases acetylcholine receptors and augments sodium channels and secondary postsynaptic membrane folding. Neurobiology of disease 20090701
A lipid-dependent uncoupled conformation of the acetylcholine receptor. The Journal of biological chemistry 20090626
Inhibition of nonneuronal alpha7-nicotinic receptor for lung cancer treatment. American journal of respiratory and critical care medicine 20090615
Is nicotine the estrogen of lung cancer? American journal of respiratory and critical care medicine 20090615
A radioisotope label-free alpha-bungarotoxin-binding assay using BIAcore sensor chip technology for real-time analysis. Analytical biochemistry 20090601
Defining pre-synaptic nicotinic receptors regulated by beta amyloid in mouse cortex and hippocampus with receptor null mutants. Journal of neurochemistry 20090601
Ric-3 chaperone-mediated stable cell-surface expression of the neuronal alpha7 nicotinic acetylcholine receptor in mammalian cells. Acta pharmacologica Sinica 20090601
Nicotinic acetylcholine receptor alpha7 subunits with a C2 cytoplasmic loop yellow fluorescent protein insertion form functional receptors. Acta pharmacologica Sinica 20090601
4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) enhances invasiveness of lung cancer cells by up-regulating contactin-1 via the alpha7 nicotinic acetylcholine receptor/ERK signaling pathway. Chemico-biological interactions 20090515
Number and locations of agonist binding sites required to activate homomeric Cys-loop receptors. The Journal of neuroscience : the official journal of the Society for Neuroscience 20090506
Presence of alpha7 nicotinic acetylcholine receptors on dorsal root ganglion neurons proved using knockout mice and selective alpha-neurotoxins in histochemistry. Journal of neurochemistry 20090501
Molecular modeling of human pentameric alpha(7) neuronal nicotinic acetylcholine receptor and its interaction with its agonist and competitive antagonist. Journal of biomolecular structure & dynamics 20090401
Detection of gymnodimine-A and 13-desmethyl C spirolide phycotoxins by fluorescence polarization. Analytical chemistry 20090401
Proteomic analysis of an alpha7 nicotinic acetylcholine receptor interactome. Journal of proteome research 20090401
Chrna7 genotype is linked with alpha7 nicotinic receptor expression but not alpha7 RNA levels. Brain research 20090331
Regional changes in the cholinergic system in mice lacking monoamine oxidase A. Brain research bulletin 20090330
PMS777, a new cholinesterase inhibitor with anti-platelet activated factor activity, regulates amyloid precursor protein processing in vitro. Neurochemical research 20090301
Palisade endings: cholinergic sensory organs or effector organs? Investigative ophthalmology & visual science 20090301
Role of the N-terminal alpha-helix in biogenesis of alpha7 nicotinic receptors. Journal of neurochemistry 20090301
Glutamate receptors localize postsynaptically at neuromuscular junctions in mice. Muscle & nerve 20090301
Design and expression of human alpha7 nicotinic acetylcholine receptor extracellular domain mutants with enhanced solubility and ligand-binding properties. Biochimica et biophysica acta 20090201
Membrane-damaging activity with A chain and B chain of beta-bungarotoxin. Toxicon : official journal of the International Society on Toxinology 20090201
Single-molecule imaging of a fluorescent unnatural amino acid incorporated into nicotinic receptors. Biophysical journal 20090107
Heteromeric co-assembly of two insect nicotinic acetylcholine receptor alpha subunits: influence on sensitivity to neonicotinoid insecticides. Journal of neurochemistry 20090101
The formation of acetylcholine receptor clusters visualized with quantum dots. BMC neuroscience 20090101
Picomolar amyloid-beta positively modulates synaptic plasticity and memory in hippocampus. The Journal of neuroscience : the official journal of the Society for Neuroscience 20081231
IgE-induced degranulation of mucosal mast cells is negatively regulated via nicotinic acetylcholine receptors. Biochemical and biophysical research communications 20081205
Nicotine inhibits apoptosis and stimulates proliferation in aortic smooth muscle cells through a functional nicotinic acetylcholine receptor. The Journal of surgical research 20081201
Nicotine and 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone induce cyclooxygenase-2 activity in human gastric cancer cells: Involvement of nicotinic acetylcholine receptor (nAChR) and beta-adrenergic receptor signaling pathways. Toxicology and applied pharmacology 20081201
Increased expression of acetylcholine receptors in the diaphragm muscle of MDX mice. Muscle & nerve 20081201
Role of alpha7-nicotinic acetylcholine receptor in human non-small cell lung cancer proliferation. Cell proliferation 20081201
Identification of a motif in the acetylcholine receptor beta subunit whose phosphorylation regulates rapsyn association and postsynaptic receptor localization. The Journal of neuroscience : the official journal of the Society for Neuroscience 20081105
The marine phycotoxin gymnodimine targets muscular and neuronal nicotinic acetylcholine receptor subtypes with high affinity. Journal of neurochemistry 20081101
Perinatal choline deficiency produces abnormal sensory inhibition in Sprague-Dawley rats. Brain research 20081027
Olanzapine improves deficient sensory inhibition in DBA/2 mice. Brain research 20081003
A novel agonist effect on the nicotinic acetylcholine receptor exerted by the anticonvulsive drug Lamotrigine. Biochimica et biophysica acta 20081001
Venom of Collett's snake (Pseudechis colletti) blocks the binding of alpha-bungarotoxin to acetylcholine receptors at chick but not human neuromuscular junctions: a histochemical study. Toxicon : official journal of the International Society on Toxinology 20081001
Schwann cells promote synaptogenesis at the neuromuscular junction via transforming growth factor-beta1. The Journal of neuroscience : the official journal of the Society for Neuroscience 20080924
Presynaptic type III neuregulin 1 is required for sustained enhancement of hippocampal transmission by nicotine and for axonal targeting of alpha7 nicotinic acetylcholine receptors. The Journal of neuroscience : the official journal of the Society for Neuroscience 20080910
Truncated CASK does not alter skeletal muscle or protein interactors. Muscle & nerve 20080901
Isoflurane prevents nicotine-evoked norepinephrine release from the mouse spinal cord at low clinical concentrations. Anesthesia and analgesia 20080901
Neural agrin increases postsynaptic ACh receptor packing by elevating rapsyn protein at the mouse neuromuscular synapse. Developmental neurobiology 20080801
Beta-Bungarotoxin induction of neurite outgrowth in NB41A3 cells. Toxicon : official journal of the International Society on Toxinology 20080801
Myotonic dystrophy transgenic mice exhibit pathologic abnormalities in diaphragm neuromuscular junctions and phrenic nerves. Journal of neuropathology and experimental neurology 20080801
A non-radioactive ligand-binding assay for detection of cyanobacterial anatoxins using Torpedo electrocyte membranes. Toxicon : official journal of the International Society on Toxinology 20080701
Effect of calcium on nicotine-induced current expressed by an atypical alpha-bungarotoxin-insensitive nAChR2. Neuroscience letters 20080627
Nicotinic receptor subtypes in rat subfornical organ neurons and glial cells. Neuroscience 20080626
Rapsyn carboxyl terminal domains mediate muscle specific kinase-induced phosphorylation of the muscle acetylcholine receptor. Neuroscience 20080602
Oxidative stress might be a mechanism connected with the decreased alpha 7 nicotinic receptor influenced by high-concentration of fluoride in SH-SY5Y neuroblastoma cells. Toxicology in vitro : an international journal published in association with BIBRA 20080601
The rescue of developing avian motoneurons from programmed cell death by a selective inhibitor of the fetal muscle-specific nicotinic acetylcholine receptor. Developmental neurobiology 20080601
Muscle-like nicotinic receptor accessory molecules in sensory hair cells of the inner ear. Molecular and cellular neurosciences 20080601
Permanent improvement in deficient sensory inhibition in DBA/2 mice with increased perinatal choline. Psychopharmacology 20080601
Postsynaptic action of brain-derived neurotrophic factor attenuates alpha7 nicotinic acetylcholine receptor-mediated responses in hippocampal interneurons. The Journal of neuroscience : the official journal of the Society for Neuroscience 20080521
Chronic nicotine and dizocilpine effects on nicotinic and NMDA glutamatergic receptor regulation: interactions with clozapine actions and attentional performance in rats. Progress in neuro-psychopharmacology & biological psychiatry 20080515
APPswe mutation increases the frequency of spontaneous Ca2+-oscillations in rat hippocampal neurons. Neuroscience letters 20080509
In vivo imaging of presynaptic terminals and postsynaptic sites in the mouse submandibular ganglion. Developmental neurobiology 20080501
Receptor-mediated tobacco toxicity: acceleration of sequential expression of alpha5 and alpha7 nicotinic receptor subunits in oral keratinocytes exposed to cigarette smoke. FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20080501
Influence of the M3-M4 intracellular domain upon nicotinic acetylcholine receptor assembly, targeting and function. British journal of pharmacology 20080401
Differentiation of inner ear stem cells to functional sensory neurons. Developmental neurobiology 20080401
Inhibition mechanism of the acetylcholine receptor by alpha-neurotoxins as revealed by normal-mode dynamics. Biochemistry 20080401
A novel serine protease inhibitor from Bungarus fasciatus venom. Peptides 20080301
Quantum dot ex vivo labeling of neuromuscular synapses. Nano letters 20080301
Functional alpha7-containing nicotinic acetylcholine receptors localize to cell bodies and proximal dendrites in the rat substantia nigra pars reticulata. The Journal of physiology 20080301
Altered hippocampal circuit function in C3H alpha7 null mutant heterozygous mice. Brain research 20080215
Interactions between loop 5 and beta-strand beta6' are involved in alpha7 nicotinic acetylcholine receptors channel gating. Journal of neurochemistry 20080201
B chain is a functional subunit of beta-bungarotoxin for inducing apoptotic death of human neuroblastoma SK-N-SH cells. Toxicon : official journal of the International Society on Toxinology 20080201
Role of pudendal afferents in voiding efficiency in the rat. American journal of physiology. Regulatory, integrative and comparative physiology 20080201
[3H]A-585539 [(1S,4S)-2,2-dimethyl-5-(6-phenylpyridazin-3-yl)-5-aza-2-azoniabicyclo[2.2.1]heptane], a novel high-affinity alpha7 neuronal nicotinic receptor agonist: radioligand binding characterization to rat and human brain. The Journal of pharmacology and experimental therapeutics 20080101
Initial synthesis and characterization of an alpha7 nicotinic receptor cellular membrane affinity chromatography column: effect of receptor subtype and cell type. Analytical chemistry 20080101
The influence of nicotine on granulocytic differentiation - inhibition of the oxidative burst and bacterial killing and increased matrix metalloproteinase-9 release. BMC cell biology 20080101
Effects of nicotine on sensorimotor gating impairment induced by long-term treatment with neurotoxic NMDA antagonism. Neurotoxicity research 20080101
Manual stimulation of the suprahyoid-sublingual region diminishes polynnervation of the motor endplates and improves recovery of function after hypoglossal nerve injury in rats. Neurorehabilitation and neural repair 20080101
The function of Shp2 tyrosine phosphatase in the dispersal of acetylcholine receptor clusters. BMC neuroscience 20080101
[11C]CHIBA-1001 as a novel PET ligand for alpha7 nicotinic receptors in the brain: a PET study in conscious monkeys. PloS one 20080101
Aromaticity at the water-hydrocarbon core interface of the membrane: consequences on the nicotinic acetylcholine receptor. Channels (Austin, Tex.) 20080101
Denervation-related changes in acetylcholine receptor density and distribution in the rat flexor digitorum sublimis muscle. Italian journal of anatomy and embryology = Archivio italiano di anatomia ed embriologia 20080101
Noradrenaline release by activation of κ-bungarotoxin-sensitive nicotinic acetylcholine receptors participates in long-term potentiation-like response induced by nicotine. Sheng li xue bao : [Acta physiologica Sinica] 20071225
Dopamine release in prefrontal cortex in response to beta-amyloid activation of alpha7 * nicotinic receptors. Brain research 20071128
Neurotization improves contractile forces of tissue-engineered skeletal muscle. Tissue engineering 20071101
Diabetic urethropathy compounds the effects of diabetic cystopathy. The Journal of urology 20071101
The subtypes of nicotinic acetylcholine receptors on dopaminergic terminals of mouse striatum. Biochemical pharmacology 20071015
Molecular properties of local anesthetics as predictors of affinity for nicotinic acetylcholine receptors. Journal of neuroscience research 20071001
Non-charged amino acids from three different domains contribute to link agonist binding to channel gating in alpha7 nicotinic acetylcholine receptors. Journal of neurochemistry 20071001
Circular dichroism studies of extracellular domains of human nicotinic acetylcholine receptors provide an insight into their structure. International journal of biological macromolecules 20071001
Identification of domains influencing assembly and ion channel properties in alpha 7 nicotinic receptor and 5-HT3 receptor subunit chimaeras. British journal of pharmacology 20071001
Does abnormal expression of acetylcholine receptors in Hirschsprung's disease induce acetylcholine esterase positive nerve fibres? Asian journal of surgery 20071001
Pharmacological and immunological identification of native alpha7 nicotinic receptors: evidence for homomeric and heteromeric alpha7 receptors. Life sciences 20070929
nAChR-mediated calcium responses and plasticity in Drosophila Kenyon cells. Developmental neurobiology 20070915
Gene targeting demonstrates that alpha4 nicotinic acetylcholine receptor subunits contribute to expression of diverse [3H]epibatidine binding sites and components of biphasic 86Rb+ efflux with high and low sensitivity to stimulation by acetylcholine. Neuropharmacology 20070901
T cells express alpha7-nicotinic acetylcholine receptor subunits that require a functional TCR and leukocyte-specific protein tyrosine kinase for nicotine-induced Ca2+ response. Journal of immunology (Baltimore, Md. : 1950) 20070901
Chlorisondamine inhibits the nicotine-induced stimulation of c-fos in the pigeon brain for up to 2 weeks. Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco 20070901
A novel extrapallial fluid protein controls the morphology of nacre lamellae in the pearl oyster, Pinctada fucata. The Journal of biological chemistry 20070810
Hairpin DNAzymes: a new tool for efficient cellular gene silencing. The journal of gene medicine 20070801
Crystal structure of the extracellular domain of nAChR alpha1 bound to alpha-bungarotoxin at 1.94 A resolution. Nature neuroscience 20070801
Evaluating the suitability of nicotinic acetylcholine receptor antibodies for standard immunodetection procedures. Journal of neurochemistry 20070701
Evidence that alpha7 nicotinic receptor modulates glutamate release from mouse neocortical gliosomes. Neurochemistry international 20070701
Acetylcholine receptor organization at the dystrophic extraocular muscle neuromuscular junction. Anatomical record (Hoboken, N.J. : 2007) 20070701
Neuroprotective effect of nicotine on dopaminergic neurons by anti-inflammatory action. The European journal of neuroscience 20070701
Specific antivenom for Bungarus candidus. Journal of the Medical Association of Thailand = Chotmaihet thangphaet 20070701
Effects of chronic neonatal nicotine exposure on nicotinic acetylcholine receptor binding, cell death and morphology in hippocampus and cerebellum. Neuroscience 20070608
The beta-amyloid protein of Alzheimer's disease binds to membrane lipids but does not bind to the alpha7 nicotinic acetylcholine receptor. Journal of neurochemistry 20070601
Genetic approaches identify differential roles for alpha4beta2* nicotinic receptors in acute models of antinociception in mice. The Journal of pharmacology and experimental therapeutics 20070601
The non-neuronal cholinergic system in peripheral blood cells: effects of nicotinic and muscarinic receptor antagonists on phagocytosis, respiratory burst and migration. Life sciences 20070530
Receptor-mediated tobacco toxicity: alterations of the NF-kappaB expression and activity downstream of alpha7 nicotinic receptor in oral keratinocytes. Life sciences 20070530
Embryonic motoneuron-skeletal muscle co-culture in a defined system. Neuroscience 20070511
alpha7 nicotinic receptor gene promoter polymorphisms in inbred mice affect expression in a cell type-specific fashion. The Journal of biological chemistry 20070504
Expression of alpha 7 nicotinic acetylcholine receptors by bipolar, amacrine, and ganglion cells of the rabbit retina. The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society 20070501
A synonymous CHRNE mutation responsible for an aberrant splicing leading to congenital myasthenic syndrome. Neuromuscular disorders : NMD 20070501
Sphingolipids are necessary for nicotinic acetylcholine receptor export in the early secretory pathway. Journal of neurochemistry 20070501
Redundancy of Cav2.1 channel accessory subunits in transmitter release at the mouse neuromuscular junction. Brain research 20070427
JN403, in vitro characterization of a novel nicotinic acetylcholine receptor alpha7 selective agonist. Neuroscience letters 20070406
The involvement of the central cholinergic system in the pressor and bradycardic effects of centrally administrated melittin in normotensive conscious rats. Neuropeptides 20070401
The role of the amino acid residue at alpha1:189 in the binding of neuromuscular blocking agents to mouse and human muscle nicotinic acetylcholine receptors. British journal of pharmacology 20070401
Increased expression of neuregulin-1 in differentiating muscle satellite cells and in motoneurons during muscle regeneration. Acta neuropathologica 20070401
Computer modeling of binding of diverse weak toxins to nicotinic acetylcholine receptors. Computational biology and chemistry 20070401
Tryptophan-scanning mutagenesis in the alphaM3 transmembrane domain of the muscle-type acetylcholine receptor. A spring model revealed. The Journal of biological chemistry 20070323
Localization of the active zone proteins CAST, ELKS, and Piccolo at neuromuscular junctions. Neuroreport 20070305
Repeated intracerebroventricular infusion of nicotine prevents kainate-induced neurotoxicity by activating the alpha7 nicotinic acetylcholine receptor. Epilepsy research 20070301
Huperzine A protects C6 rat glioma cells against oxygen-glucose deprivation-induced injury. FEBS letters 20070220
Cytoplasmic regions adjacent to the M3 and M4 transmembrane segments influence expression and function of alpha7 nicotinic acetylcholine receptors. A study with single amino acid mutants. Journal of neurochemistry 20070101
Involvement of c-Jun-JNK pathways in the regulation of programmed cell death of developing chick embryo spinal cord motoneurons. Developmental neuroscience 20070101
Cholesterol depletion activates rapid internalization of submicron-sized acetylcholine receptor domains at the cell membrane. Molecular membrane biology 20070101
Strychnine, but not PMBA, inhibits neuronal nicotinic acetylcholine receptors expressed by rabbit retinal ganglion cells. Visual neuroscience 20070101
Structural determinants for alpha-neurotoxin sensitivity in muscle nAChR and their implications for the gating mechanism. Channels (Austin, Tex.) 20070101
[Modulation of skeletal muscle contraction by the non-toxic fraction of Buthus occitanus tunetanus venom via the cholinergic receptors]. Archives de l'Institut Pasteur de Tunis 20070101
Influence of agonists and antagonists on the segmental motion of residues near the agonist binding pocket of the acetylcholine-binding protein. The Journal of biological chemistry 20061222
Design, synthesis, structure-activity relationship, and in vivo activity of azabicyclic aryl amides as alpha7 nicotinic acetylcholine receptor agonists. Bioorganic & medicinal chemistry 20061215
Nicotinic acetylcholine receptors on basophils and mast cells. Anaesthesia 20061201
Development of hippocampal alpha7 nicotinic receptors in C3H and DBA/2 congenic mice. Brain research 20061129
Reversible disruption of dynactin 1-mediated retrograde axonal transport in polyglutamine-induced motor neuron degeneration. The Journal of neuroscience : the official journal of the Society for Neuroscience 20061122
Fluorophore-assisted light inactivation produces both targeted and collateral effects on N-type calcium channel modulation in rat sympathetic neurons. The Journal of physiology 20061015
Chronic neonatal nicotine upregulates heteromeric nicotinic acetylcholine receptor binding without change in subunit mRNA expression. Brain research 20061003
The nicotinic receptor antagonists abolish pathobiologic effects of tobacco-derived nitrosamines on BEP2D cells. Journal of cancer research and clinical oncology 20061001
Synaptic GABAA receptors are directly recruited from their extrasynaptic counterparts. The EMBO journal 20060920
Involvement of alpha-bungarotoxin-sensitive nicotinic receptors in long-term memory formation in the honeybee (Apis mellifera). Neurobiology of learning and memory 20060901
Mechanism of beta-bungarotoxin in facilitating spontaneous transmitter release at neuromuscular synapse. Neuropharmacology 20060901
Cholinergic regulation of endogenous morphine release from lobster nerve cord. Medical science monitor : international medical journal of experimental and clinical research 20060901
alpha7 Nicotinic acetylcholine receptor stimulation inhibits lipopolysaccharide-induced interleukin-18 and -12 production in monocytes. Journal of pharmacological sciences 20060901
Failure of nicotine-dependent enhancement of synaptic efficacy at Schaffer-collateral CA1 synapses of AD11 anti-nerve growth factor transgenic mice. The European journal of neuroscience 20060901
Inhibition of two different cholinesterases by tacrine. Chemico-biological interactions 20060825
An autoradiographic analysis of [125I]alpha-bungarotoxin binding in rat brain after chronic nicotine exposure. Neuroscience letters 20060814
Fast cholinergic efferent inhibition in guinea pig outer hair cells. Brain research 20060802
Neuregulin effect on quantal content dissociated from effect on miniature endplate potential amplitude. Journal of neurophysiology 20060801
Extremely low-frequency electromagnetic field (ELF-EMF) does not affect the expression of alpha3, alpha5 and alpha7 nicotinic receptor subunit genes in SH-SY5Y neuroblastoma cell line. Toxicology letters 20060714
Ca2+ entry through plasma membrane IP3 receptors. Science (New York, N.Y.) 20060714
Slow-channel mutation in acetylcholine receptor alphaM4 domain and its efficient knockdown. Annals of neurology 20060701
Visualization of integral and peripheral cell surface proteins in live Caenorhabditis elegans. Journal of neuroscience methods 20060630
Phosphorylation of the nicotinic acetylcholine receptor in myotube-cholinergic neuron cocultures. Journal of neuroscience research 20060601
Expression of the alpha7, alpha4 and alpha3 nicotinic receptor subtype in the brain and adrenal medulla of transgenic mice carrying genes coding for human AChE and beta-amyloid. International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience 20060601
Lipid rafts serve as a signaling platform for nicotinic acetylcholine receptor clustering. The Journal of neuroscience : the official journal of the Society for Neuroscience 20060503
P2X(7) receptors exert a permissive role on the activation of release-enhancing presynaptic alpha7 nicotinic receptors co-existing on rat neocortex glutamatergic terminals. Neuropharmacology 20060501
Heterogeneity of neuromuscular junctions in striated muscle of human esophagus demonstrated by triple staining for the vesicular acetylcholine transporter, alpha-bungarotoxin, and acetylcholinesterase. Cell and tissue research 20060501
Myogenin-dependent nAChR clustering in aneural myotubes. Molecular and cellular neurosciences 20060401
[Cloning of alpha-bungarotoxin gene and its prokaryotic expression as a non-fusion protein]. Yi chuan = Hereditas 20060401
In vivo effects of the anatoxin-a on striatal dopamine release. Neurochemical research 20060401
Molecular cloning of the major lethal toxins from two kraits (Bungarus flaviceps and Bungarus candidus). Toxicon : official journal of the International Society on Toxinology 20060315
Non-neuronal nicotinic alpha 7 receptor, a new endothelial target for revascularization. Life sciences 20060313
Protein kinase Ciota promotes nicotine-induced migration and invasion of cancer cells via phosphorylation of micro- and m-calpains. The Journal of biological chemistry 20060217
Nicotine stimulates adhesion molecular expression via calcium influx and mitogen-activated protein kinases in human endothelial cells. The international journal of biochemistry & cell biology 20060201
Unexpected sensitivity of the human alpha7 neuronal nicotinic acetylcholine receptor to aminoglycosides. Neuroreport 20060123
Improved gating of a chimeric alpha7-5HT3A receptor upon mutations at the M2-M3 extracellular loop. FEBS letters 20060109
CASK localizes to nuclei in developing skeletal muscle and motor neuron culture models and is agrin-independent. Journal of cellular physiology 20060101
Tissue inhibitor of metalloproteinase-2(TIMP-2)-deficient mice display motor deficits. Journal of neurobiology 20060101
Galantamine increases excitability of CA1 hippocampal pyramidal neurons. Neuroscience 20060101
Association of nicotinic acetylcholine receptors with central respiratory control in isolated brainstem-spinal cord preparation of neonatal rats. Biological research 20060101
A unified view of the role of electrostatic interactions in modulating the gating of Cys loop receptors. The Journal of biological chemistry 20051216
Alpha7-acetylcholine receptor antibodies in two patients with Rasmussen encephalitis. Neurology 20051213
Presynaptic modulation of synaptic transmission by pregnenolone sulfate as studied by optical recordings. Journal of neurophysiology 20051201
Nicotinic acetylcholine receptor subtypes involved in facilitation of GABAergic inhibition in mouse superficial superior colliculus. Journal of neurophysiology 20051201
Envenoming bites by kraits: the biological basis of treatment-resistant neuromuscular paralysis. Brain : a journal of neurology 20051201
Long-term exposure to the new nicotinic antagonist 1,2-bisN-cytisinylethane upregulates nicotinic receptor subtypes of SH-SY5Y human neuroblastoma cells. British journal of pharmacology 20051201
Pharmacological profiles of recombinant and native insect nicotinic acetylcholine receptors. Insect biochemistry and molecular biology 20051201
Lovastatin stimulates up-regulation of alpha7 nicotinic receptors in cultured neurons without cholesterol dependency, a mechanism involving production of the alpha-form of secreted amyloid precursor protein. Journal of neuroscience research 20051115
Acetylcholine and calcium signalling regulates muscle fibre formation in the zebrafish embryo. Journal of cell science 20051115
Src-family kinases stabilize the neuromuscular synapse in vivo via protein interactions, phosphorylation, and cytoskeletal linkage of acetylcholine receptors. The Journal of neuroscience : the official journal of the Society for Neuroscience 20051109
IBM-type inclusions in a patient with slow-channel syndrome caused by a mutation in the AChR epsilon subunit. Neuromuscular disorders : NMD 20051101
Alpha7 neuronal nicotinic acetylcholine receptors are negatively regulated by tyrosine phosphorylation and Src-family kinases. The Journal of neuroscience : the official journal of the Society for Neuroscience 20051026
Identification of nicotinic acetylcholine receptor recycling and its role in maintaining receptor density at the neuromuscular junction in vivo. The Journal of neuroscience : the official journal of the Society for Neuroscience 20051026
Inhibition of alpha7-nicotinic acetylcholine receptor expression by arsenite in the vascular endothelial cells. Toxicology letters 20051015
Mice deficient in CHRNA7, a subunit of the nicotinic acetylcholine receptor, produce sperm with impaired motility. Biology of reproduction 20051001
Synaptically released and exogenous ACh activates different nicotinic receptors to enhance evoked glutamatergic transmission in the lateral geniculate nucleus. Journal of neurophysiology 20051001
Reversal of isolation-rearing-induced PPI deficits by an alpha7 nicotinic receptor agonist. Psychopharmacology 20051001
Autocrine activation of nicotinic acetylcholine receptors contributes to Ca2+ spikes in mouse myotubes during myogenesis. The Journal of physiology 20051001
Early changes in Abeta levels in the brain of APPswe transgenic mice--implication on synaptic density, alpha7 neuronal nicotinic acetylcholine- and N-methyl-D-aspartate receptor levels. Molecular and cellular neurosciences 20051001
Inhibition of N-methyl-D-aspartate receptors increases paraoxon-induced apoptosis in cultured neurons. Toxicology and applied pharmacology 20051001
Desensitization of alpha7 nicotinic receptors potentiated the inhibitory effect on M-current induced by stimulation of muscarinic receptors in rat superior cervical ganglion neurons. Journal of neural transmission (Vienna, Austria : 1996) 20050901
A novel alpha-conotoxin, PeIA, cloned from Conus pergrandis, discriminates between rat alpha9alpha10 and alpha7 nicotinic cholinergic receptors. The Journal of biological chemistry 20050826
Two-dimensional measurement of proton T1rho relaxation in unlabeled proteins: mobility changes in alpha-bungarotoxin upon binding of an acetylcholine receptor peptide. Biochemistry 20050816
Phospholipase A(2) activity of beta-bungarotoxin is essential for induction of cytotoxicity on cerebellar granule neurons. Journal of neurobiology 20050801
Nonmuscle myosins IIA and IIB are present in adult motor nerve terminals. Neuroreport 20050801
Decreased number of acetylcholine receptors is the mechanism that alters the time course of muscle relaxants in myasthenia gravis: a study in a rat model. European journal of anaesthesiology 20050801
Crystal structure of acetylcholine-binding protein from Bulinus truncatus reveals the conserved structural scaffold and sites of variation in nicotinic acetylcholine receptors. The Journal of biological chemistry 20050715
Nicotinic receptors regulate B lymphocyte activation and immune response. European journal of pharmacology 20050711
Presynaptic alpha7 and non-alpha7 nicotinic acetylcholine receptors modulate [3H]d-aspartate release from rat frontal cortex in vitro. Neuropharmacology 20050701
[Molecular cloning and expression of an isotoxin gene, alpha-bungarotoxin, from Bungarus multicinctus]. Yi chuan xue bao = Acta genetica Sinica 20050701
The involvement of central cholinergic system in the pressor effect of intracerebroventricularly injected U-46619, a thromboxane A2 analog, in conscious normotensive rats. Naunyn-Schmiedeberg's archives of pharmacology 20050701
NCAM 180 acting via a conserved C-terminal domain and MLCK is essential for effective transmission with repetitive stimulation. Neuron 20050616
The Drosophila acetylcholine receptor subunit D alpha5 is part of an alpha-bungarotoxin binding acetylcholine receptor. The Journal of biological chemistry 20050603
Mutation of single murine acetylcholine receptor subunits reveals differential contribution of P121 to acetylcholine binding and channel opening. Pflugers Archiv : European journal of physiology 20050601
Contribution of a snake venom toxin to myasthenia gravis: the discovery of alpha-bungarotoxin in Taiwan. Journal of the history of the neurosciences 20050601
Stimulation of nicotinic acetylcholine receptors protects motor neurons. Biochemical and biophysical research communications 20050520
Neurotransmitter acetylcholine negatively regulates neuromuscular synapse formation by a Cdk5-dependent mechanism. Neuron 20050519
Interaction of acetylcholine with Kir6.1 channels heterologously expressed in human embryonic kidney cells. European journal of pharmacology 20050516
Functionality of nitrated acetylcholine receptor: the two-step formation of nitrotyrosines reveals their differential role in effectors binding. FEBS letters 20050509
An ultrasensitive protein array based on electrochemical enzyme immunoassay. Frontiers in bioscience : a journal and virtual library 20050501
Role of alpha7-nicotinic acetylcholine receptors in tetanic stimulation-induced gamma oscillations in rat hippocampal slices. Neuropharmacology 20050501
Chronic nicotine and dizocilpine effects on regionally specific nicotinic and NMDA glutamate receptor binding. Brain research 20050418
Rapid upregulation of alpha7 nicotinic acetylcholine receptors by tyrosine dephosphorylation. The Journal of neuroscience : the official journal of the Society for Neuroscience 20050406
High-affinity epibatidine binding of functional, human alpha7-nicotinic acetylcholine receptors stably and heterologously expressed de novo in human SH-EP1 cells. The Journal of pharmacology and experimental therapeutics 20050401
Neurotoxins in axenic oscillatorian cyanobacteria: coexistence of anatoxin-a and homoanatoxin-a determined by ligand-binding assay and GC/MS. Microbiology (Reading, England) 20050401
Neurotrophin-3 null mutant mice display a postnatal motor neuropathy. The European journal of neuroscience 20050401
Influence of melatonin on the development of functional nicotinic acetylcholine receptors in cultured chick retinal cells. Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas 20050401
Taiwan cobra chymotrypsin inhibitor: cloning, functional expression and gene organization. Biochimica et biophysica acta 20050314
Regulation of motoneuron excitability via motor endplate acetylcholine receptor activation. The Journal of neuroscience : the official journal of the Society for Neuroscience 20050302
Alpha 7 nicotinic receptor subunit is present on serotonin neurons projecting to hippocampus and septum. Synapse (New York, N.Y.) 20050301
Relationship between alpha 7 nAChR and apoptosis in human lymphocytes. Journal of neuroimmunology 20050301
alpha1-Adrenergic mechanism in diabetic urethral dysfunction in rats. The Journal of urology 20050301
Effects of cholinergic receptor agonists and antagonists on miniature stimulatory postsynaptic ionic currents in somatic muscle cells of lumbricus terrestris. Bulletin of experimental biology and medicine 20050301
A family of acetylcholine-gated chloride channel subunits in Caenorhabditis elegans. The Journal of biological chemistry 20050225
Galantamine activates muscle-type nicotinic acetylcholine receptors without binding to the acetylcholine-binding site. The Journal of neuroscience : the official journal of the Society for Neuroscience 20050223
Coordinated motor neuron axon growth and neuromuscular synaptogenesis are promoted by CPG15 in vivo. Neuron 20050217
Genetic correlation between the free-choice oral consumption of nicotine and alcohol in C57BL/6JxC3H/HeJ F2 intercross mice. Behavioural brain research 20050210
The structural events associated with the binding of divalent cations to beta-bungarotoxin. Toxicon : official journal of the International Society on Toxinology 20050201
Lys-64 of the A chain is involved in the enzymatic activity and neurotoxic effect of beta-bungarotoxin. Toxicon : official journal of the International Society on Toxinology 20050201
Evidence for functional nicotinic receptors on pancreatic beta cells. Metabolism: clinical and experimental 20050201
Effects of Abeta1-42 fibrils and of the tetrapeptide Pr-IIGL on the phosphorylation state of the tau-protein and on the alpha7 nicotinic acetylcholine receptor in vitro. The European journal of neuroscience 20050201
Ric-3 promotes functional expression of the nicotinic acetylcholine receptor alpha7 subunit in mammalian cells. The Journal of biological chemistry 20050114
Antennal tactile learning in the honeybee: effect of nicotinic antagonists on memory dynamics. Neuroscience 20050101
The linoleic acid derivative FR236924 facilitates hippocampal synaptic transmission by enhancing activity of presynaptic alpha7 acetylcholine receptors on the glutamatergic terminals. Neuroscience 20050101
Different nicotinic acetylcholine receptor subtypes mediating striatal and prefrontal cortical [3H]dopamine release. Neuropharmacology 20050101
Interaction of corticosterone and nicotine in regulation of prepulse inhibition in mice. Neuropharmacology 20050101
Molecular characteristics suggest an effector function of palisade endings in extraocular muscles. Investigative ophthalmology & visual science 20050101
A rat model of slow Wallerian degeneration (WldS) with improved preservation of neuromuscular synapses. The European journal of neuroscience 20050101
Antinociceptive effects of choline against acute and inflammatory pain. Neuroscience 20050101
The alpha7 nicotinic acetylcholine receptor: molecular modelling, electrostatics, and energetics. Molecular membrane biology 20050101
Gene dosage-dependent transmitter release changes at neuromuscular synapses of CACNA1A R192Q knockin mice are non-progressive and do not lead to morphological changes or muscle weakness. Neuroscience 20050101
Chronic exposure to typical or atypical antipsychotics in rodents: temporal effects on central alpha7 nicotinic acetylcholine receptors. Neuroscience 20050101
Effect of amyloid peptides on the increase in TrkA receptor expression induced by nicotine in vitro and in vivo. Journal of molecular neuroscience : MN 20050101
Sequence-induced trimerization of phospholipase A2: structure of a trimeric isoform of PLA2 from common krait (Bungarus caeruleus) at 2.5 A resolution. Acta crystallographica. Section F, Structural biology and crystallization communications 20050101
Precise localization of alpha7 nicotinic acetylcholine receptors on glutamatergic axon terminals in the rat ventral tegmental area. The Journal of neuroscience : the official journal of the Society for Neuroscience 20041215
Nicotine enhancement of dopamine release by a calcium-dependent increase in the size of the readily releasable pool of synaptic vesicles. The Journal of neuroscience : the official journal of the Society for Neuroscience 20041215
A novel pharmatope tag inserted into the beta4 subunit confers allosteric modulation to neuronal nicotinic receptors. The Journal of biological chemistry 20041203
Nicotine and epibatidine triggered prolonged rise in calcium and TH gene transcription in PC12 cells. European journal of pharmacology 20041203
Solution structure of gamma-bungarotoxin: the functional significance of amino acid residues flanking the RGD motif in integrin binding. Proteins 20041201
Origin of acetylcholinesterase in the neuromuscular junction formed in the in vitro innervated human muscle. The European journal of neuroscience 20041201
Progressive abnormalities in skeletal muscle and neuromuscular junctions of transgenic mice expressing the Huntington's disease mutation. The European journal of neuroscience 20041201
Neuronal nicotinic receptors: from structure to pathology. Progress in neurobiology 20041201
The role of palmitoylation in functional expression of nicotinic alpha7 receptors. The Journal of neuroscience : the official journal of the Society for Neuroscience 20041117
Drosophila nicotinic receptors: evidence for imidacloprid insecticide and alpha-bungarotoxin binding to distinct sites. Neuroscience letters 20041116
Identified spinal motoneurons of young rats possess nicotinic acetylcholine receptors of the heteromeric family. The European journal of neuroscience 20041101
Regulation of nicotinic receptor expression by the ubiquitin-proteasome system. The EMBO journal 20041027
Neurophysiological and immunohistochemical studies on Guillain-Barre syndrome with IgG anti-GalNAc-GD1a antibodies-effects on neuromuscular transmission. Journal of the neurological sciences 20041015
Alpha-conotoxin residues that interact at close range with gamma-tyrosine-111 and mutant delta-tyrosine-113 on the Torpedo nicotinic acetylcholine receptor. Biochemistry 20041005
The modulating role of nuclear factor-kappaB in the action of alpha7-nicotinic acetylcholine receptor and cross-talk between 5-lipoxygenase and cyclooxygenase-2 in colon cancer growth induced by 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone. The Journal of pharmacology and experimental therapeutics 20041001
Prenatal nicotine exposure alters the types of nicotinic receptors that facilitate excitatory inputs to cardiac vagal neurons. Journal of neurophysiology 20041001
Reduced expression of nicotinic AChRs in myotubes from spinal muscular atrophy I patients. Laboratory investigation; a journal of technical methods and pathology 20041001
Desensitizing and non-desensitizing subtypes of alpha-bungarotoxin-sensitive nicotinic acetylcholine receptors in cockroach neurons. Journal of insect physiology 20041001
A morphological technique for exploring neuromuscular topography expressed in the mouse gluteus maximus muscle. Journal of neuroscience methods 20040930
Tobacco-specific nitrosamine 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone promotes functional cooperation of Bcl2 and c-Myc through phosphorylation in regulating cell survival and proliferation. The Journal of biological chemistry 20040917
Soluble, oligomeric, and ligand-binding extracellular domain of the human alpha7 acetylcholine receptor expressed in yeast: replacement of the hydrophobic cysteine loop by the hydrophilic loop of the ACh-binding protein enhances protein solubility. The Journal of biological chemistry 20040910
Differential regulation of dopamine D1 and D2 signaling by nicotine in neostriatal neurons. Journal of neurochemistry 20040901
Acetylcholinesterase inhibitors increase ADAM10 activity by promoting its trafficking in neuroblastoma cell lines. Journal of neurochemistry 20040901
The spatiotemporal characterization of endplate reoccupation, with special reference to the superposition patterns of the presynaptic elements and the postsynaptic receptor regions during muscle reinnervation. Journal of the peripheral nervous system : JPNS 20040901
Maternal exposure to nicotine and chlorpyrifos, alone and in combination, leads to persistently elevated expression of glial fibrillary acidic protein in the cerebellum of the offspring in late puberty. Archives of toxicology 20040801
Methyllycaconitine, alpha-bungarotoxin and (+)-tubocurarine block fast ATP-gated currents in rat dorsal root ganglion cells. British journal of pharmacology 20040801
Distribution of calcitonin gene-related peptide at the neuromuscular junction of mdx mice. The anatomical record. Part A, Discoveries in molecular, cellular, and evolutionary biology 20040801
Acrylodan-conjugated cysteine side chains reveal conformational state and ligand site locations of the acetylcholine-binding protein. The Journal of biological chemistry 20040702
Nicotinic acetylcholine receptor subtypes expression during rat retina development and their regulation by visual experience. Molecular pharmacology 20040701
Molecular characterization of Dalpha6 and Dalpha7 nicotinic acetylcholine receptor subunits from Drosophila: formation of a high-affinity alpha-bungarotoxin binding site revealed by expression of subunit chimeras. Journal of neurochemistry 20040701
NMR and MD studies on the interaction between ligand peptides and alpha-bungarotoxin. Journal of molecular biology 20040618
Acetylcholinesterase function is dispensable for sensory neurite growth but is critical for neuromuscular synapse stability. Developmental biology 20040601
Iodo-alpha-conotoxin MI selectively binds the alpha/delta subunit interface of muscle nicotinic acetylcholine receptors. Biochemistry 20040601
Prenatal nicotine exposure increases connective tissue expression in foetal monkey pulmonary vessels. The European respiratory journal 20040601
Acetylcholine protection of adult pig retinal ganglion cells from glutamate-induced excitotoxicity. Investigative ophthalmology & visual science 20040501
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The solution structure of the complex formed between alpha-bungarotoxin and an 18-mer cognate peptide derived from the alpha 1 subunit of the nicotinic acetylcholine receptor from Torpedo californica. The Journal of biological chemistry 20010622
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