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            CAS No: 127191-97-3 Catalog No: AG000WQW MDL No:MFCD00083180
| Title | Journal | 
|---|---|
| An in vitro skin sensitization assay termed EpiSensA for broad sets of chemicals including lipophilic chemicals and pre/pro-haptens. | Toxicology in vitro : an international journal published in association with BIBRA 20170401 | 
| Plasticizer DBP Activates NLRP3 Inflammasome through the P2X7 Receptor in HepG2 and L02 Cells. | Journal of biochemical and molecular toxicology 20160401 | 
| Toluene diisocyanate: Induction of the autotaxin-lysophosphatidic acid axis and its association with airways symptoms. | Toxicology and applied pharmacology 20150915 | 
| Involvement of CaM-CaMKII-ERK in bisphenol A-induced Sertoli cell apoptosis. | Toxicology 20141003 | 
| Identification of potent Yes1 kinase inhibitors using a library screening approach. | Bioorganic & medicinal chemistry letters 20130801 | 
| Neuroprotective effect of resveratrol on ischemia/reperfusion injury in rats through TRPC6/CREB pathways. | Journal of molecular neuroscience : MN 20130701 | 
| A broad activity screen in support of a chemogenomic map for kinase signalling research and drug discovery. | The Biochemical journal 20130415 | 
| Calcium/calmodulin-dependent protein kinase II regulates IL-10 production by human T lymphocytes: a distinct target in the calcium dependent pathway. | Molecular immunology 20120901 | 
| NOX2-dependent ROS is required for HDAC5 nuclear efflux and contributes to HDAC4 nuclear efflux during intense repetitive activity of fast skeletal muscle fibers. | American journal of physiology. Cell physiology 20120801 | 
| Pannexin1-mediated ATP release provides signal transmission between Neuro2A cells. | Neurochemical research 20120601 | 
| Structure-activity relationships and optimization of 3,5-dichloropyridine derivatives as novel P2X(7) receptor antagonists. | Journal of medicinal chemistry 20120426 | 
| Purinergic P2X7 receptors participate in disturbed intracellular calcium homeostasis in peripheral blood mononuclear cells of patients with chronic kidney disease. | Kidney & blood pressure research 20120101 | 
| The affinity of histamine for Gq protein-coupled histamine H(1)-receptors is predominantly regulated by their internalization in human astrocytoma cells. | Journal of pharmacological sciences 20120101 | 
| Exocrine pancreatic carcinogenesis and autotaxin expression. | PloS one 20120101 | 
| Adipocyte P2X7 receptors expression: a role in modulating inflammatory response in subjects with metabolic syndrome? | Atherosclerosis 20111201 | 
| CRP1, a protein localized in filopodia of growth cones, is involved in dendritic growth. | The Journal of neuroscience : the official journal of the Society for Neuroscience 20111116 | 
| Pharmacological properties of the rhesus macaque monkey P2X7 receptor. | British journal of pharmacology 20110901 | 
| Involvement of histaminergic receptor mechanisms in the stimulation of NT-3 synthesis in astrocytes. | Neuropharmacology 20110601 | 
| NMDA preconditioning protects against quinolinic acid-induced seizures via PKA, PI3K and MAPK/ERK signaling pathways. | Behavioural brain research 20110516 | 
| TGF-β-activated kinase 1 mediates mechanical stress-induced IL-6 expression in osteoblasts. | Biochemical and biophysical research communications 20110506 | 
| Characterization of protoberberine analogs employed as novel human P2X7 receptor antagonists. | Toxicology and applied pharmacology 20110415 | 
| Requirement for non-regulated, constitutive calcium influx in macrophage survival signaling. | Biochemical and biophysical research communications 20110408 | 
| LTP in hippocampal neurons is associated with a CaMKII-mediated increase in GluA1 surface expression. | Journal of neurochemistry 20110201 | 
| Calmodulin and calmodulin-dependent protein kinase II inhibit hormone secretion in human parathyroid adenoma. | The Journal of endocrinology 20110101 | 
| 4-aminopyridine induces apoptosis of human acute myeloid leukemia cells via increasing [Ca2+]i through P2X7 receptor pathway. | Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 20110101 | 
| Targeting P2X₇ receptor inhibits the metastasis of murine P388D1 lymphoid neoplasm cells to lymph nodes. | Cell biology international 20101201 | 
| Pathways for ATP release by bovine ciliary epithelial cells, the initial step in purinergic regulation of aqueous humor inflow. | American journal of physiology. Cell physiology 20101201 | 
| TGF-β1 prevents up-regulation of the P2X7 receptor by IFN-γ and LPS in leukemic THP-1 monocytes. | Biochimica et biophysica acta 20101101 | 
| Mechanism of inhibition of acetylcholine secretion in newly formed mouse synapses involving Ca2+-dependent kinases and voltage-gated K+-channels. | Bulletin of experimental biology and medicine 20100801 | 
| Osthole or imperatorin-mediated facilitation of glutamate release is associated with a synaptic vesicle mobilization in rat hippocampal glutamatergic nerve endings. | Synapse (New York, N.Y.) 20100501 | 
| Shockwaves increase T-cell proliferation and IL-2 expression through ATP release, P2X7 receptors, and FAK activation. | American journal of physiology. Cell physiology 20100301 | 
| Delayed intrinsic activation of an NMDA-independent CaM-kinase II in a critical time window is necessary for late consolidation of an associative memory. | The Journal of neuroscience : the official journal of the Society for Neuroscience 20100106 | 
| Rebound bursts in GABAergic neurons of the thalamic reticular nucleus in postnatal mice. | Physiological research 20100101 | 
| Vacuolar ATPase regulates surfactant secretion in rat alveolar type II cells by modulating lamellar body calcium. | PloS one 20100101 | 
| Defining the antigen receptor-dependent regulatory network that induces arrest of cycling immature B-lymphocytes. | BMC systems biology 20100101 | 
| Synthesis and structure-activity relationships of pyrazolodiazepine derivatives as human P2X7 receptor antagonists. | Bioorganic & medicinal chemistry letters 20091101 | 
| Acetylcholine rescues two-cell block through activation of IP3 receptors and Ca2+/calmodulin-dependent kinase II in an ICR mouse strain. | Pflugers Archiv : European journal of physiology 20091001 | 
| Modulation of K(ATP) currents in rat ventricular myocytes by hypoxia and a redox reaction. | Acta pharmacologica Sinica 20091001 | 
| Role of calcineurin-mediated dephosphorylation in modulation of an inwardly rectifying K+ channel in human proximal tubule cells. | The Journal of membrane biology 20091001 | 
| A highly energetic process couples calcium influx through L-type calcium channels to insulin secretion in pancreatic beta-cells. | American journal of physiology. Endocrinology and metabolism 20090901 | 
| A role for calcium-calmodulin-dependent protein kinase II in the consolidation of visual object recognition memory. | The European journal of neuroscience 20090901 | 
| P2X7-mediated increased intracellular calcium causes functional derangement in Schwann cells from rats with CMT1A neuropathy. | The Journal of biological chemistry 20090821 | 
| Purinergic P2X(7) receptor antagonists: Chemistry and fundamentals of biological screening. | Bioorganic & medicinal chemistry 20090715 | 
| Up-regulation of ZO-1 expression and barrier function in cultured human corneal epithelial cells by substance P. | FEBS letters 20090618 | 
| Expression of the dominant-negative tail of myosin Va enhances exocytosis of large dense core vesicles in neurons. | Cellular and molecular neurobiology 20090601 | 
| Antagonists of the P2X(7) receptor. From lead identification to drug development. | Journal of medicinal chemistry 20090528 | 
| Activation of ROS/NF-kappaB and Ca2+/CaM kinase II are necessary for VCAM-1 induction in IL-1beta-treated human tracheal smooth muscle cells. | Toxicology and applied pharmacology 20090515 | 
| The role of P2X7 receptor in ATP-mediated human leukemia cell death: calcium influx-independent. | Acta biochimica et biophysica Sinica 20090501 | 
| Astrocyte cultures exhibit P2X7 receptor channel opening in the absence of exogenous ligands. | Glia 20090415 | 
| Synthesis and structure-activity relationships of novel, substituted 5,6-dihydrodibenzo[a,g]quinolizinium P2X7 antagonists. | Bioorganic & medicinal chemistry letters 20090201 | 
| Search for inhibitors of bacterial and human protein kinases among derivatives of diazepines[1,4] annelated with maleimide and indole cycles. | Journal of medicinal chemistry 20081225 | 
| Destabilization of the postsynaptic density by PSD-95 serine 73 phosphorylation inhibits spine growth and synaptic plasticity. | Neuron 20081210 | 
| Identification of regions of the P2X(7) receptor that contribute to human and rat species differences in antagonist effects. | British journal of pharmacology 20081101 | 
| CaMKII-mediated phosphorylation of the myosin motor Myo1c is required for insulin-stimulated GLUT4 translocation in adipocytes. | Cell metabolism 20081101 | 
| P2X7 receptor-Pannexin1 complex: pharmacology and signaling. | American journal of physiology. Cell physiology 20080901 | 
| Silencing-induced metaplasticity in hippocampal cultured neurons. | Journal of neurophysiology 20080801 | 
| Constitutive activity of inwardly rectifying K+ channel at physiological [Ca]i is mediated by Ca2+/CaMK II pathway in opossum kidney proximal tubule cells. | The journal of physiological sciences : JPS 20080601 | 
| [Effects of chronic hypoxia on the expression of calmodulin and calcicum/calmodulin-dependent protein kinase II and the calcium activity in myocardial cells in young rats]. | Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics 20080601 | 
| Receptor-mediated tobacco toxicity: acceleration of sequential expression of alpha5 and alpha7 nicotinic receptor subunits in oral keratinocytes exposed to cigarette smoke. | FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20080501 | 
| Induction of nuclear receptors and drug resistance in the brain microvascular endothelial cells treated with antiepileptic drugs. | Current neurovascular research 20080501 | 
| Depolarization-induced differentiation of PC12 cells is mediated by phospholipase D2 through the transcription factor CREB pathway. | Journal of neurochemistry 20080301 | 
| A plant Ca2+ pump, ACA2, relieves salt hypersensitivity in yeast. Modulation of cytosolic calcium signature and activation of adaptive Na+ homeostasis. | The Journal of biological chemistry 20080208 | 
| Role for calcium in the development of ovarial patency in Heliothis virescens. | Journal of insect physiology 20080201 | 
| Cloning and pharmacological characterization of the guinea pig P2X7 receptor orthologue. | British journal of pharmacology 20080201 | 
| Negative and positive allosteric modulators of the P2X(7) receptor. | British journal of pharmacology 20080201 | 
| Synthesis and structure-activity relationship studies of tyrosine-based antagonists at the human P2X7 receptor. | Bioorganic & medicinal chemistry letters 20080115 | 
| Extracellular ATP mediates necrotic cell swelling in SN4741 dopaminergic neurons through P2X7 receptors. | The Journal of biological chemistry 20071228 | 
| Functional expression of ionotropic purinergic receptors on mouse taste bud cells. | The Journal of physiology 20071015 | 
| Behavioral modulation of neuronal calcium/calmodulin-dependent protein kinase II activity: differential effects on nicotine-induced spinal and supraspinal antinociception in mice. | Biochemical pharmacology 20071015 | 
| Contribution of two ionotropic purinergic receptors to ATP responses in submandibular gland ductal cells. | Cellular signalling 20071001 | 
| Calcium/calmodulin-dependent kinase activity is required for efficient induction of osteoclast differentiation and bone resorption by receptor activator of nuclear factor kappa B ligand (RANKL). | Journal of cellular physiology 20070901 | 
| A quantitative method for routine measurement of cell surface P2X7 receptor function in leucocyte subsets by two-colour time-resolved flow cytometry. | Journal of immunological methods 20070831 | 
| Hepatocyte growth factor-induced enhancement of dendritic branching is blocked by inhibitors of N-methyl-D-aspartate receptors and calcium/calmodulin-dependent kinases. | Journal of neuroscience research 20070815 | 
| From tyrosine to glycine: synthesis and biological activity of potent antagonists of the purinergic P2X7 receptor. | Journal of medicinal chemistry 20070726 | 
| KN-62 analogues as potent differentiating agents of HL-60 cells. | Leukemia research 20070501 | 
| Multiple P2X receptors are involved in the modulation of apoptosis in human mesangial cells: evidence for a role of P2X4. | American journal of physiology. Renal physiology 20070501 | 
| CaMKII regulates retinoic acid receptor transcriptional activity and the differentiation of myeloid leukemia cells. | The Journal of clinical investigation 20070501 | 
| Corticotropin-releasing hormone or dexamethasone regulates rat proopiomelanocortin transcription through Tpit/Pitx-responsive element in its promoter. | The Journal of endocrinology 20070501 | 
| Calcium signalling in the regulation of PGC-1alpha, PDK4 and HKII mRNA expression. | Biological chemistry 20070501 | 
| Activity-dependent initiation of a prolonged depolarization in aplysia bag cell neurons: role for a cation channel. | Journal of neurophysiology 20070301 | 
| The select action of hippocampal calcium calmodulin protein kinase II in mediating exercise-enhanced cognitive function. | Neuroscience 20070209 | 
| Stimulation of adenosine A1 and A2A receptors by AMP in the submucosal plexus of guinea pig small intestine. | American journal of physiology. Gastrointestinal and liver physiology 20070201 | 
| Microarray-based kinase inhibition assay by gold nanoparticle probes. | Analytical chemistry 20070115 | 
| Stimulation of fibroblast proliferation by neokyotorphin requires Ca influx and activation of PKA, CaMK II and MAPK/ERK. | The FEBS journal 20070101 | 
| Life and death in bovine monocytes: the fate of Mycobacterium avium subsp. paratuberculosis. | Microbial pathogenesis 20070101 | 
| The retinoic acid receptor/CaMKII interaction: pharmacologic inhibition of CaMKII enhances the differentiation of myeloid leukemia cells. | Blood cells, molecules & diseases 20070101 | 
| Cocaine activates calcium/calmodulin kinase II and causes cardiomyocyte hypertrophy. | Journal of cardiovascular pharmacology 20060701 | 
| Modulation by LL-37 of the responses of salivary glands to purinergic agonists. | Molecular pharmacology 20060601 | 
| Microsphere-based protease assays and screening application for lethal factor and factor Xa. | Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501 | 
| Activation of P2Y1 receptor triggers two calcium signaling pathways in bone marrow erythroblasts. | European journal of pharmacology 20060318 | 
| Pore properties and pharmacological features of the P2X receptor channel in airway ciliated cells. | The Journal of physiology 20060315 | 
| Internalization and desensitization of a green fluorescent protein-tagged P2Y nucleotide receptor are differently controlled by inhibition of calmodulin-dependent protein kinase II. | Journal of neurochemistry 20060201 | 
| Overexpression of calbindin-D28K in hippocampal progenitor cells increases neuronal differentiation and neurite outgrowth. | FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20060101 | 
| Cocaine inhibition of GABA(A) current: role of dephosphorylation. | Critical reviews in neurobiology 20060101 | 
| Modulation of intracellular Ca2+ release and capacitative Ca2+ entry by CaMKII inhibitors in bovine vascular endothelial cells. | American journal of physiology. Cell physiology 20051201 | 
| N-Arylpiperazine modified analogues of the P2X7 receptor KN-62 antagonist are potent inducers of apoptosis of human primary osteoclasts. | Journal of biomedical science 20051201 | 
| Calcium-acting drugs modulate expression and development of chronic tolerance to nicotine-induced antinociception in mice. | The Journal of pharmacology and experimental therapeutics 20051101 | 
| Calcium/calmodulin-dependent protein kinase II (CaMKII), through NMDA receptors and L-Voltage-gated channels, modulates the serine phosphorylation of GluR6 during cerebral ischemia and early reperfusion period in rat hippocampus. | Brain research. Molecular brain research 20051031 | 
| Gonadotropin-releasing hormone induction of extracellular-signal regulated kinase is blocked by inhibition of calmodulin. | Molecular endocrinology (Baltimore, Md.) 20050901 | 
| Human melanomas express functional P2 X(7) receptors. | Cell and tissue research 20050901 | 
| Human epidermal and monocyte-derived langerhans cells express functional P2X receptors. | The Journal of investigative dermatology 20050901 | 
| Netrin-1 induces axon branching in developing cortical neurons by frequency-dependent calcium signaling pathways. | The Journal of neuroscience : the official journal of the Society for Neuroscience 20050713 | 
| Effects of 17beta-estradiol on chemically induced long-term depression. | Neuropharmacology 20050701 | 
| Neuroprotective effects of preconditioning ischemia on ischemic brain injury through down-regulating activation of JNK1/2 via N-methyl-D-aspartate receptor-mediated Akt1 activation. | The Journal of biological chemistry 20050610 | 
| The role of intracellular Ca2+ in the regulation of proteinase-activated receptor-2 mediated nuclear factor kappa B signalling in keratinocytes. | British journal of pharmacology 20050601 | 
| Activation of CREB by tauroursodeoxycholic acid protects cholangiocytes from apoptosis induced by mTOR inhibition. | Hepatology (Baltimore, Md.) 20050601 | 
| Decreases in CaMKII activity trigger persistent potentiation of intrinsic excitability in spontaneously firing vestibular nucleus neurons. | Neuron 20050519 | 
| Nuclear Ca2+ and CaM kinase IV specify hormonal- and Notch-responsiveness. | Journal of neurochemistry 20050401 | 
| Activity-dependent long-term potentiation of intrinsic excitability in hippocampal CA1 pyramidal neurons. | The Journal of neuroscience : the official journal of the Society for Neuroscience 20050216 | 
| Somatodendritic autoreceptor regulation of serotonergic neurons: dependence on L-tryptophan and tryptophan hydroxylase-activating kinases. | The European journal of neuroscience 20050201 | 
| Heterologous desensitization of insulin secretion by GIP (glucose-dependent insulinotropic peptide) in INS-1 cells: the significance of Galphai2 and investigations on the mechanism involved. | Cell biochemistry and function 20050101 | 
| Extracellular zinc triggers ERK-dependent activation of Na+/H+ exchange in colonocytes mediated by the zinc-sensing receptor. | The Journal of biological chemistry 20041210 | 
| AMP-activated protein kinase: a new beta-cell glucose sensor?: Regulation by amino acids and calcium ions. | Diabetes 20041201 | 
| Chlamydophila pneumoniae induces p44/p42 mitogen-activated protein kinase activation in human fibroblasts through Toll-like receptor 4. | Journal of medical microbiology 20041201 | 
| Synthesis, radiolabeling, and preliminary biological evaluation of [3H]-1-[(S)-N,O-bis-(isoquinolinesulfonyl)-N-methyl-tyrosyl]-4-(o-tolyl)-piperazine, a potent antagonist radioligand for the P2X7 receptor. | Bioorganic & medicinal chemistry letters 20041115 | 
| Extracellular ATP increases cation fluxes in human erythrocytes by activation of the P2X7 receptor. | The Journal of biological chemistry 20041022 | 
| Mechanisms intrinsic to 5-HT2B receptor-induced potentiation of NMDA receptor responses in frog motoneurones. | British journal of pharmacology 20041001 | 
| Enhanced P2X7 activity in human fibroblasts from diabetic patients: a possible pathogenetic mechanism for vascular damage in diabetes. | Arteriosclerosis, thrombosis, and vascular biology 20040701 | 
| Chelerythrine and other benzophenanthridine alkaloids block the human P2X7 receptor. | British journal of pharmacology 20040701 | 
| Endothelin 1 and 3 enhance neuronal nitric oxide synthase activity through ETB receptors involving multiple signaling pathways in the rat anterior hypothalamus. | Peptides 20040701 | 
| KN-62, a selective inhibitor of Ca(2+)/calmodulin-dependent protein kinase II, inhibits the lysozyme pre-mRNA splicing in myelomonocytic HD11 cells. | Biochemical and biophysical research communications 20040625 | 
| Diurnal, circadian and photic regulation of calcium/calmodulin-dependent kinase II and neuronal nitric oxide synthase in the hamster suprachiasmatic nuclei. | Neurochemistry international 20040601 | 
| Brain ischemia induces serine phosphorylation of neuronal nitric oxide synthase by Ca(2+)/calmodulin-dependent protein kinase II in rat hippocampus. | Acta pharmacologica Sinica 20040501 | 
| A novel P2X7 receptor activator, the human cathelicidin-derived peptide LL37, induces IL-1 beta processing and release. | Journal of immunology (Baltimore, Md. : 1950) 20040415 | 
| Signaling pathway of magnolol-stimulated lipolysis in sterol ester-loaded 3T3-L1 preadipocyes. | Journal of cellular biochemistry 20040401 | 
| Pavlovian fear conditioning regulates Thr286 autophosphorylation of Ca2+/calmodulin-dependent protein kinase II at lateral amygdala synapses. | The Journal of neuroscience : the official journal of the Society for Neuroscience 20040331 | 
| Ca2+ and AMPK both mediate stimulation of glucose transport by muscle contractions. | Diabetes 20040201 | 
| Evidence that protein kinase Cdelta is not required for palmitate-induced cytotoxicity in BRIN-BD11 beta-cells. | Journal of molecular endocrinology 20040201 | 
| Competitive binding of postsynaptic density 95 and Ca2+-calmodulin dependent protein kinase II to N-methyl-D-aspartate receptor subunit 2B in rat brain. | Acta pharmacologica Sinica 20040201 | 
| A role for calcium/calmodulin kinase in insulin stimulated glucose transport. | Life sciences 20040102 | 
| NMDA receptor-mediated immediate Ser831 phosphorylation of GluR1 through CaMKIIalpha in rat hippocampus during early global ischemia. | Neuroscience research 20040101 | 
| Nicotinamide relaxes vascular smooth muscle by inhibiting myosin light chain kinase-dependent signaling pathways: implications for anticancer efficacy. | Oncology research 20040101 | 
| Agonists and antagonists acting at P2X7 receptor. | Current topics in medicinal chemistry 20040101 | 
| Dissecting individual current components of co-expressed human P2X1 and P2X7 receptors. | Current topics in medicinal chemistry 20040101 | 
| Inhibition of lipopolysaccharide/ATP-induced release of interleukin-18 by KN-62 and glyburide. | European journal of pharmacology 20031215 | 
| Hit-to-Lead studies: the discovery of potent adamantane amide P2X7 receptor antagonists. | Bioorganic & medicinal chemistry letters 20031117 | 
| Dopamine D1 receptors mediate CREB phosphorylation via phosphorylation of the NMDA receptor at Ser897-NR1. | Journal of neurochemistry 20031101 | 
| Cerebral ischemia immediately increases serine phosphorylation of the synaptic RAS-GTPase activating protein SynGAP by calcium/calmodulin-dependent protein kinase II alpha in hippocampus of rats. | Neuroscience letters 20031009 | 
| Signalling pathways involved in the sensitisation of mouse nociceptive neurones by nerve growth factor. | The Journal of physiology 20030901 | 
| Beta-adrenergic stimulation induces cardiac ankyrin repeat protein expression: involvement of protein kinase A and calmodulin-dependent kinase. | Cardiovascular research 20030901 | 
| Striatal proenkephalin gene induction: coordinated regulation by cyclic AMP and calcium pathways. | Brain research. Molecular brain research 20030723 | 
| Regulation of ERK phosphorylation by ethanol in fetal cortical neurons. | Neurochemical research 20030501 | 
| Ca2+/calmodulin-dependent protein kinases II and IV both promote survival but differ in their effects on axon growth in spiral ganglion neurons. | Journal of neuroscience research 20030415 | 
| Synthesis and biological activity of N-arylpiperazine-modified analogues of KN-62, a potent antagonist of the purinergic P2X7 receptor. | Journal of medicinal chemistry 20030410 | 
| Insulin-stimulated cyclic guanosine monophosphate inhibits vascular smooth muscle cell migration by inhibiting Ca/calmodulin-dependent protein kinase II. | Circulation 20030325 | 
| Ameliorative effect of NC-1900, a new AVP4-9 analog, through vasopressin V1A receptor on scopolamine-induced impairments of spatial memory in the eight-arm radial maze. | Neuropharmacology 20030301 | 
| Calmodulin and calmodulin-dependent kinase II mediate neuronal cell death induced by depolarization. | Brain research 20030207 | 
| The role of the nuclear receptor CAR as a coordinate regulator of hepatic gene expression in defense against chemical toxicity. | Archives of biochemistry and biophysics 20030101 | 
| Formation of AP-1 transcription factors during learning in Helix. | Neuroscience and behavioral physiology 20030101 | 
| A calcium/calmodulin kinase pathway connects brain-derived neurotrophic factor to the cyclic AMP-responsive transcription factor in the rat hippocampus. | Neuroscience 20030101 | 
| c-IAP1 is overexpressed in HL-60 cells selected for doxorubicin resistance: effects on etoposide-induced apoptosis. | Anticancer research 20030101 | 
| Synapsin I is phosphorylated at Ser603 by p21-activated kinases (PAKs) in vitro and in PC12 cells stimulated with bradykinin. | The Journal of biological chemistry 20021122 | 
| Proteasome-driven turnover of tryptophan hydroxylase is triggered by phosphorylation in RBL2H3 cells, a serotonin producing mast cell line. | European journal of biochemistry 20021001 | 
| Postsynaptic kinase signaling underlies inhibitory synaptic plasticity in the lateral superior olive. | Journal of neurobiology 20021001 | 
| KN-62 enhances Chlamydia pneumoniae-induced p44/p42 mitogen-activated protein kinase activation in murine fibroblasts and attenuates in vitro infection. | FEMS microbiology letters 20020924 | 
| Purine and pyrimidine (P2) receptors as drug targets. | Journal of medicinal chemistry 20020912 | 
| Mechanisms of mitogenic and anti-apoptotic signaling by glucose-dependent insulinotropic polypeptide in beta(INS-1)-cells. | The Journal of endocrinology 20020801 | 
| Ca(2+)/calmodulin-dependent protein kinase (CaM-kinase) inhibitor KN-62 suppresses the activity of mitogen-activated protein kinase (MAPK), c-myc activation and human keratinocyte proliferation. | Archives of dermatological research 20020701 | 
| CaMKII regulates amphetamine-induced ERK1/2 phosphorylation in striatal neurons. | Neuroreport 20020612 | 
| CaMKII is activated and translocated to the secretory apical membrane during cholinergically conveyed gastric acid secretion. | Cellular signalling 20020201 | 
| Pharmacological characterization of the P2X(7) receptor on human macrophages using the patch-clamp technique. | Naunyn-Schmiedeberg's archives of pharmacology 20020201 | 
| Protein kinase C increases 11beta-hydroxysteroid dehydrogenase oxidation and inhibits reduction in rat Leydig cells. | Journal of andrology 20020101 | 
| Synthesis, biological activity and molecular modeling studies of 1,2,3,4-tetrahydroisoquinoline derivatives as conformationally constrained analogues of KN62, a potent antagonist of the P2X7-receptor containing a tyrosine moiety. | Arzneimittel-Forschung 20020101 | 
| Effects of calcium, calmodulin, protein kinase C and protein tyrosine kinases on volume-activated taurine efflux in human erythroleukemia cells. | Journal of cellular physiology 20011201 | 
| Calmodulin and a cyclic nucleotide-dependent protein kinase facilitate the prolactin-induced increase in tyrosine hydroxylase activity in tuberoinfundibular dopaminergic neurons. | Endocrine 20011101 | 
| Ameliorative effect of vasopressin-(4-9) through vasopressin V(1A) receptor on scopolamine-induced impairments of rat spatial memory in the eight-arm radial maze. | European journal of pharmacology 20010907 | 
| Functional characterization of P2Y and P2X receptors in human eosinophils. | Journal of cellular physiology 20010901 | 
| P2Y(11) receptor expression by human lymphocytes: evidence for two cAMP-linked purinoceptors. | European journal of pharmacology 20010831 | 
| Complex intracellular messenger pathways regulate one type of neuronal alpha-bungarotoxin-resistant nicotinic acetylcholine receptors expressed in insect neurosecretory cells (dorsal unpaired median neurons). | Molecular pharmacology 20010701 | 
| Glutamate induces focal adhesion kinase tyrosine phosphorylation and actin rearrangement in heterologous mGluR1-expressing CHO cells via calcium/calmodulin signaling. | Journal of neurochemistry 20010701 | 
| Histamine production by cultured microglial cells of the mouse. | Neuroscience letters 20010615 | 
| Stimulation of astrocyte-enriched culture with C2 ceramide increases proenkephalin mRNA: involvement of cAMP-response element binding protein and mitogen activated protein kinases. | Brain research 20010608 | 
| CAMKII inhibition in the parabrachial nuclei elicits conditioned taste aversion in rats. | Neurobiology of learning and memory 20010501 | 
| Induction of differentiation of human myeloid leukemia cells by immunosuppressant macrolides (rapamycin and FK506) and calcium/calmodulin-dependent kinase inhibitors. | Experimental hematology 20010501 | 
| Complexities of measuring antagonist potency at P2X(7) receptor orthologs. | The Journal of pharmacology and experimental therapeutics 20010301 | 
| Modulation of the neuronal dopamine transporter activity by the metabotropic glutamate receptor mGluR5 in rat striatal synaptosomes through phosphorylation mediated processes. | Journal of neurochemistry 20010301 | 
| The stimulation of MAP kinase by 1,25(OH)(2)-vitamin D(3) in skeletal muscle cells is mediated by protein kinase C and calcium. | Molecular and cellular endocrinology 20010227 | 
| Inhibition of PP-2A upregulates CaMKII in rat forebrain and induces hyperphosphorylation of tau at Ser 262/356. | FEBS letters 20010209 | 
| The CEACAM1-L Ser503 residue is crucial for inhibition of colon cancer cell tumorigenicity. | Oncogene 20010111 | 
| Modulation of choline acetyltransferase synthesis by okadaic acid, a phosphatase inhibitor, and KN-62, a CaM kinase inhibitor, in NS-20Y neuroblastoma. | Neurochemistry international 20010101 | 
| Effects of extracellular calcium and potassium on the sodium pump of rat adrenal glomerulosa cells. | American journal of physiology. Cell physiology 20010101 | 
| A proposed mechanism for the potentiation of cAMP-mediated acid secretion by carbachol. | American journal of physiology. Cell physiology 20010101 | 
| Cell cycle phase specificity in the potentiation of etoposide-induced DNA damage and apoptosis by KN-62, an inhibitor of calcium-calmodulin-dependent enzymes. | Biochemical pharmacology 20010101 | 
| Calmodulin kinases II and IV and calcineurin are involved in leukemia inhibitory factor-induced cardiac hypertrophy in rats. | Circulation research 20001110 | 
| Estrogen activation of the nuclear orphan receptor CAR (constitutive active receptor) in induction of the mouse Cyp2b10 gene. | Molecular endocrinology (Baltimore, Md.) 20001101 | 
| Specificity and mechanism of action of some commonly used protein kinase inhibitors. | The Biochemical journal 20001001 | 
| Signal-dependent activation of the MEF2 transcription factor by dissociation from histone deacetylases. | Proceedings of the National Academy of Sciences of the United States of America 20000411 | 
| MAP kinase-independent induction of proto-oncogene c-fos mRNA by hemin in human cells. | Biochemical and biophysical research communications 19990624 | 
| Effects of antagonists at the human recombinant P2X7 receptor. | British journal of pharmacology 19980701 | 
| Differential effects of omega-conotoxin GVIA, nimodipine, calmidazolium and KN-62 injected intrathecally on the antinociception induced by beta-endorphin, morphine and [D-Ala2,N-MePhe4,Gly-ol5]-enkephalin administered intracerebroventricularly in the mouse. | The Journal of pharmacology and experimental therapeutics 19970801 | 
| The isoquinoline derivative KN-62 a potent antagonist of the P2Z-receptor of human lymphocytes. | British journal of pharmacology 19970401 | 
| Inhibition of sandfly fever Sicilian virus (Phlebovirus) replication in vitro by antiviral compounds. | Research in virology 19970101 | 
| KN-62, 1-[N,O-bis(5-isoquinolinesulfonyl)-N-methyl-L-tyrosyl]-4-phenylpiperazi ne, a specific inhibitor of Ca2+/calmodulin-dependent protein kinase II. | The Journal of biological chemistry 19900315 | 
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