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CAS No: 127-48-0 Catalog No: AG000WIU MDL No:MFCD00047084
Title | Journal |
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Discriminating between adaptive and carcinogenic liver hypertrophy in rat studies using logistic ridge regression analysis of toxicogenomic data: The mode of action and predictive models. | Toxicology and applied pharmacology 20170301 |
[Toxic effects of trimethadione on zebrafish early development]. | Yi chuan = Hereditas 20120901 |
Update on endoscopic management of main pancreatic duct stones in chronic calcific pancreatitis. | The Korean journal of internal medicine 20120301 |
Induction of specific immunotherapy with hymenoptera venoms using ultrarush regimen in children: safety and tolerance. | Journal of allergy 20120101 |
Genetic polymorphisms in CYP2E1: association with schizophrenia susceptibility and risperidone response in the Chinese Han population. | PloS one 20120101 |
Short-term long chain omega3 diet protects from neuroinflammatory processes and memory impairment in aged mice. | PloS one 20120101 |
Translating clinical findings into knowledge in drug safety evaluation--drug induced liver injury prediction system (DILIps). | PLoS computational biology 20111201 |
Treatment of myasthenia gravis based on its immunopathogenesis. | Journal of clinical neurology (Seoul, Korea) 20111201 |
Co-variation in frequency and severity of cardiovascular and skeletal defects in Sprague-Dawley rats after maternal administration of dimethadione, the N-demethylated metabolite of trimethadione. | Birth defects research. Part B, Developmental and reproductive toxicology 20110601 |
Zebrafish (Danio rerio) embryos as a model for testing proteratogens. | Toxicology 20110315 |
Cognitive and emotional alterations are related to hippocampal inflammation in a mouse model of metabolic syndrome. | PloS one 20110101 |
Studies of properties of 'Pain Networks' as predictors of targets of stimulation for treatment of pain. | Frontiers in integrative neuroscience 20110101 |
Intrauterine growth retardation and nonalcoholic Fatty liver disease in children. | International journal of endocrinology 20110101 |
A predictive ligand-based Bayesian model for human drug-induced liver injury. | Drug metabolism and disposition: the biological fate of chemicals 20101201 |
Synthesis and SAR studies of 1,4-benzoxazine MenB inhibitors: novel antibacterial agents against Mycobacterium tuberculosis. | Bioorganic & medicinal chemistry letters 20101101 |
Lamotrigine extends lifespan but compromises health span in Drosophila melanogaster. | Biogerontology 20100201 |
Allyl isothiocyanate that induces GST and UGT expression confers oxidative stress resistance on C. elegans, as demonstrated by nematode biosensor. | PloS one 20100101 |
Neuroprotective effects of blockers for T-type calcium channels. | Molecular neurodegeneration 20090101 |
Treatment of Lennox-Gastaut syndrome: overview and recent findings. | Neuropsychiatric disease and treatment 20081201 |
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors. | Journal of medicinal chemistry 20081113 |
The anticonvulsant ethosuximide disrupts sensory function to extend C. elegans lifespan. | PLoS genetics 20081001 |
Valproic acid extends Caenorhabditis elegans lifespan. | Aging cell 20080601 |
Design and synthesis of 6-amino-1,4-oxazepane-3,5-dione derivatives as novel broad spectrum anticonvulsants. | Bioorganic & medicinal chemistry letters 20080601 |
Etiology of congenital dislocation of the hip : Carl E. Badgley MD (1893-1973). The 11th president of the AAOS 1942. | Clinical orthopaedics and related research 20080101 |
Effect of optical flow versus attentional strategy on gait in Parkinson's Disease: a study with a portable optical stimulating device. | Journal of neuroengineering and rehabilitation 20080101 |
Prophylactic and therapeutic functions of T-type calcium blockers against noise-induced hearing loss. | Hearing research 20070401 |
Classification and diagnosis of ear malformations. | GMS current topics in otorhinolaryngology, head and neck surgery 20070101 |
The ethics of excluding women who become pregnant while participating in clinical trials of anti-epileptic medications. | Seizure 20061201 |
Pharmacology of delayed aging and extended lifespan of Caenorhabditis elegans. | Experimental gerontology 20061001 |
Education and imaging. Hepatobiliary and pancreatic: oral therapy for pancreatic duct stones. | Journal of gastroenterology and hepatology 20060901 |
Microsphere-based protease assays and screening application for lethal factor and factor Xa. | Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501 |
Effects of anticonvulsant drugs on life span. | Archives of neurology 20060401 |
The history of barbiturates a century after their clinical introduction. | Neuropsychiatric disease and treatment 20051201 |
The antihyperalgesic effects of the T-type calcium channel blockers ethosuximide, trimethadione, and mibefradil. | European journal of pharmacology 20051003 |
Extrapolation of human pharmacokinetic parameters from rat, dog, and monkey data: Molecular properties associated with extrapolative success or failure. | Journal of pharmaceutical sciences 20050701 |
Oral litholysis therapy for endoscopically unretrievable obstructive pancreatic stones. | Pancreas 20050501 |
Adulteration of South African traditional herbal remedies. | Therapeutic drug monitoring 20050201 |
Anticonvulsant medications extend worm life-span. | Science (New York, N.Y.) 20050114 |
Postnatal closure of membranous ventricular septal defects in Sprague-Dawley rat pups after maternal exposure with trimethadione. | Birth defects research. Part B, Developmental and reproductive toxicology 20040601 |
Involvement of cytochrome P450 2C9, 2E1 and 3A4 in trimethadione N-demethylation in human microsomes. | Journal of clinical pharmacy and therapeutics 20031201 |
Embryonic arrhythmia by inhibition of HERG channels: a common hypoxia-related teratogenic mechanism for antiepileptic drugs? | Epilepsia 20020501 |
Determination of trimetazidine HCl by adsorptive stripping square-wave voltammetry at a glassy carbon electrode. | Journal of pharmaceutical and biomedical analysis 20020101 |
The clinical importance of the trimethadione tolerance test as a method for quantitative assessment of hepatic functional reserve in patients with biliary atresia. | Journal of clinical pharmacy and therapeutics 20011201 |
Pharmacological characterization of the 6 Hz psychomotor seizure model of partial epilepsy. | Epilepsy research 20011201 |
[Fetal trimethadione syndrome]. | Ryoikibetsu shokogun shirizu 20010101 |
Anticonvulsants for soman-induced seizure activity. | Journal of biomedical science 19990101 |
Trimethadione N-demethylation by rat liver CYP2E1 in vitro. | Research communications in molecular pathology and pharmacology 19960701 |
Characterization of the antiabsence effects of SCH 50911, a GABA-B receptor antagonist, in the lethargic mouse, gamma-hydroxybutyrate, and pentylenetetrazole models. | The Journal of pharmacology and experimental therapeutics 19950901 |
Dissolution of pancreatic stones by oral trimethadione in patients with chronic calcific pancreatitis. | Journal of gastroenterology and hepatology 19940101 |
Effects of the oxazolidinedione anticonvulsants trimethadione and dimethadione and the barbiturate homolog 5,5-dimethylbarbituric acid on N-nitrosodiethylamine-initiated renal and hepatic carcinogenesis in the F344/NCr rat. | Archives of toxicology 19920101 |
Anticonvulsive and convulsive effects of lidocaine: comparison with those of phenytoin, and implications for mechanism of action concepts. | Neurological research 19880901 |
Effects of antiepileptic drugs on absence-like and tonic seizures in the spontaneously epileptic rat, a double mutant rat. | Epilepsia 19880101 |
Only certain antiepileptic drugs prevent seizures induced by pilocarpine. | Brain research 19870701 |
Use of ethosuximide and valproate in the treatment of epilepsy. | Neurologic clinics 19860801 |
Antiepileptic drug evaluation in a new animal model: spontaneous petit mal epilepsy in the rat. | Arzneimittel-Forschung 19850101 |
Fetal anticonvulsant syndrome in rats: effects on postnatal behavior and brain amino acid content. | Neurobehavioral toxicology and teratology 19850101 |
A model of chronic spontaneous petit mal-like seizures in the rat: comparison with pentylenetetrazol-induced seizures. | Epilepsia 19840601 |
Fetal anticonvulsant syndrome in rats: dose- and period-response relationships of prenatal diphenylhydantoin, trimethadione and phenobarbital exposure on the structural and functional development of the offspring. | The Journal of pharmacology and experimental therapeutics 19831101 |
Comparison of the actions of trimethadione and chlordiazepoxide in animal models of anxiety and benzodiazepine receptor binding. | Neuropharmacology 19821101 |
Anticonvulsants specific for petit mal antagonize epileptogenic effect of leucine enkephalin. | Science (New York, N.Y.) 19801128 |
Troxidone (trimethadione) embryopathy: case report with reveiw of the literature. | Clinical and experimental neurology 19790101 |
Phenotypic malformations in association with maternal trimethadione therapy. | The Journal of pediatrics 19780201 |
Anti-convulsant effect of phthalazino-2,3b-phthalazine-5(14H),12(7h)-dione (L-5418). I. Behavioral effect. | Japanese journal of pharmacology 19780201 |
The fetal trimethadione syndrome: report of an additional family and further delineation of this syndrome. | American journal of diseases of children (1960) 19771201 |
[Quantitative analysis of conditional-optimal doses of succilep and trimetin in the treatment of children and adolescents with minor forms of epilepsy]. | Zhurnal nevropatologii i psikhiatrii imeni S.S. Korsakova (Moscow, Russia : 1952) 19770101 |
Measurement of anticonvulsant activity in the Papio papio model of epilepsy. | Federation proceedings 19760901 |
Cardiac defects in children of mothers receiving anticonvulsant therapy during pregnancy. | The Journal of pediatrics 19760801 |
Di-n-propylacetic acid--profile of anticonvulsant activity in mice. | Arzneimittel-Forschung 19760201 |
The fetal trimethadione syndrome. | The Journal of pediatrics 19750801 |
Fetal anomalies following maternal trimethadione ingestion. | The Journal of pediatrics 19730501 |
Trimethadione (Tridione)-induced nephrotic syndrome. A report of a case with unique ultrastructural renal pathology. | The American journal of medicine 19730201 |
Possible teratogenicity of trimethadione and paramethadione. | Lancet (London, England) 19700801 |
Pharmacologic interactions of albutoin with other anticonvulsant drugs. | The Journal of pharmacology and experimental therapeutics 19700801 |
Myasthenia gravis syndrome associated with trimethadione. | JAMA 19700629 |
Successful therapy of trimethadione nephrosis with prednisone and cyclophosphamide. Report of a case. | The Journal of pediatrics 19670801 |
Nephrotic syndrome caused by probenecid. | JAMA 19670102 |
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