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126872-16-0 | α-Ribofuranose
CAS No: 126872-16-0 Catalog No: AG000TET MDL No:
Product Description
Catalog Number:
AG000TET
Chemical Name:
α-Ribofuranose
CAS Number:
126872-16-0
Molecular Formula:
C5H10O5
Molecular Weight:
150.1299
IUPAC Name:
(2S,3R,4S,5R)-5-(hydroxymethyl)oxolane-2,3,4-triol
InChI:
InChI=1S/C5H10O5/c6-1-2-3(7)4(8)5(9)10-2/h2-9H,1H2/t2-,3-,4-,5+/m1/s1
InChI Key:
HMFHBZSHGGEWLO-AIHAYLRMSA-N
SMILES:
OC[C@H]1O[C@@H]([C@@H]([C@@H]1O)O)O
UNII:
6R5AZ534G3
Properties
Complexity:
117
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
1
Defined Atom Stereocenter Count:
4
Defined Bond Stereocenter Count:
0
Exact Mass:
150.053g/mol
Formal Charge:
0
Heavy Atom Count:
10
Hydrogen Bond Acceptor Count:
5
Hydrogen Bond Donor Count:
4
Isotope Atom Count:
0
Molecular Weight:
150.13g/mol
Monoisotopic Mass:
150.053g/mol
Rotatable Bond Count:
1
Topological Polar Surface Area:
90.2A^2
Undefined Atom Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
XLogP3:
-2
Literature
| Title | Journal |
|---|---|
| Evaluation of α-D-ribofuranose (D-ribose) toxicity after intravenous administration to rabbits. | Human & experimental toxicology 20120801 |
| Molecular differences between a mutase and a phosphatase: investigations of the activation step in Bacillus cereus phosphopentomutase. | Biochemistry 20120306 |
| Is boron a prebiotic element? A mini-review of the essentiality of boron for the appearance of life on earth. | Origins of life and evolution of the biosphere : the journal of the International Society for the Study of the Origin of Life 20120201 |
| Insights into the mechanism of bovine CD38/NAD+glycohydrolase from the X-ray structures of its Michaelis complex and covalently-trapped intermediates. | PloS one 20120101 |
| Antiviral Ability of Kalanchoe gracilis Leaf Extract against Enterovirus 71 and Coxsackievirus A16. | Evidence-based complementary and alternative medicine : eCAM 20120101 |
| Wild-type phosphoribosylpyrophosphate synthase (PRS) from Mycobacterium tuberculosis: a bacterial class II PRS? | PloS one 20120101 |
| tRNA structural and functional changes induced by oxidative stress. | Cellular and molecular life sciences : CMLS 20111201 |
| Central AMP-activated protein kinase affects sympathetic nerve activity in rats. | Neuroscience letters 20111010 |
| N-Benzyl-1,3-dide-oxy-1,3-imino-l-xylitol. | Acta crystallographica. Section E, Structure reports online 20110901 |
| Desulfurization of 2-thiouracil nucleosides: conformational studies of 4-pyrimidinone nucleosides. | Bioorganic & medicinal chemistry 20110401 |
| Bacillus cereus phosphopentomutase is an alkaline phosphatase family member that exhibits an altered entry point into the catalytic cycle. | The Journal of biological chemistry 20110311 |
| Hepatic glycogen supercompensation activates AMP-activated protein kinase, impairs insulin signaling, and reduces glycogen deposition in the liver. | Diabetes 20110201 |
| Synthesis of cyclic adenosine 5'-diphosphate ribose analogues: a C2'endo/syn 'southern' ribose conformation underlies activity at the sea urchin cADPR receptor. | Organic & biomolecular chemistry 20110107 |
| Diagnostic properties of metabolic perturbations in rheumatoid arthritis. | Arthritis research & therapy 20110101 |
| 1-(2-Bromo-2-de-oxy-β-d-xylofuranos-yl)uracil. | Acta crystallographica. Section E, Structure reports online 20110101 |
| Biosynthesis of galactofuranose in kinetoplastids: novel therapeutic targets for treating leishmaniasis and chagas' disease. | Enzyme research 20110101 |
| Lithium suppresses astrogliogenesis by neural stem and progenitor cells by inhibiting STAT3 pathway independently of glycogen synthase kinase 3 beta. | PloS one 20110101 |
| Cholera- and anthrax-like toxins are among several new ADP-ribosyltransferases. | PLoS computational biology 20101201 |
| 1,2,3-Tri-O-acetyl-5-de-oxy-d-ribofuran-ose. | Acta crystallographica. Section E, Structure reports online 20101201 |
| Structural and genetic characterization of the O-antigen of Salmonella enterica O56 containing a novel derivative of 4-amino-4,6-dideoxy-D-glucose. | Carbohydrate research 20100903 |
| Crystallization and preliminary X-ray analysis of a phosphopentomutase from Bacillus cereus. | Acta crystallographica. Section F, Structural biology and crystallization communications 20100701 |
| New trends in nucleoside biotechnology. | Acta naturae 20100701 |
| Peroxisome proliferator-activated receptor gamma coactivator 1alpha or 1beta overexpression inhibits muscle protein degradation, induction of ubiquitin ligases, and disuse atrophy. | The Journal of biological chemistry 20100618 |
| To eat or not to eat: the effect of AICAR on food intake regulation in yellow-bellied marmots (Marmota flaviventris). | The Journal of experimental biology 20100615 |
| New antioxidant flavonoid isolated from Leuzea carthamoides. | Journal of enzyme inhibition and medicinal chemistry 20100201 |
| EPO receptor gain-of-function causes hereditary polycythemia, alters CD34 cell differentiation and increases circulating endothelial precursors. | PloS one 20100101 |
| CaMKK is an upstream signal of AMP-activated protein kinase in regulation of substrate metabolism in contracting skeletal muscle. | American journal of physiology. Regulatory, integrative and comparative physiology 20091201 |
| Preliminary crystallographic studies of purine nucleoside phosphorylase from the cariogenic pathogen Streptococcus mutans. | Acta crystallographica. Section F, Structural biology and crystallization communications 20091201 |
| Rates of in situ transcription and splicing in large human genes. | Nature structural & molecular biology 20091101 |
| Ribocation transition state capture and rebound in human purine nucleoside phosphorylase. | Chemistry & biology 20090925 |
| A toyocamycin analogue with the sugar moiety in a syn conformation. | Acta crystallographica. Section C, Crystal structure communications 20090901 |
| Abstracts of the 2008 ISSOL Meeting. August 24-29, 2008. Florence, Italy. | Origins of life and evolution of the biosphere : the journal of the International Society for the Study of the Origin of Life 20090801 |
| Blunting of AICAR-induced human skeletal muscle glucose uptake in type 2 diabetes is dependent on age rather than diabetic status. | American journal of physiology. Endocrinology and metabolism 20090501 |
| D-ribose competitively reverses inhibition by D-psicose of larval growth in Caenorhabditis elegans. | Biological & pharmaceutical bulletin 20090501 |
| Activation of IP(3) receptors by synthetic bisphosphate ligands. | Chemical communications (Cambridge, England) 20090314 |
| Toward understanding the conformational dynamics of RNA ligation. | Biochemistry 20090203 |
| From simple diols to carbohydrate derivatives of phenylarsonic acid. | Inorganic chemistry 20090202 |
| AICAR preconditioning prevents postischemic leukocyte rolling and adhesion: role of K(ATP) channels and heme oxygenase. | Microcirculation (New York, N.Y. : 1994) 20090201 |
| Enzymatic primer-extension with glycerol-nucleoside triphosphates on DNA templates. | PloS one 20090101 |
| Filling kinetic gaps: dynamic modeling of metabolism where detailed kinetic information is lacking. | PloS one 20090101 |
| Synthesis of phosphonate and phostone analogues of ribose-1-phosphates. | Beilstein journal of organic chemistry 20090101 |
| Effects of angiotensin II receptor blockade on glucose metabolism via AMP-activated protein kinase in insulin-resistant hypertensive rats. | Journal of the American Society of Hypertension : JASH 20090101 |
| Modulation of the type I hypersensitivity late phase reaction to OVA by Propionibacterium acnes-soluble polysaccharide. | Immunology letters 20081222 |
| Phosphorylation of nucleosides and nucleotides with inorganic monoimido-cyclo-triphosphate. | Chemical & pharmaceutical bulletin 20081201 |
| Highly beta-selective C-allylation of a ribofuranoside controlling steric hindrance in the transition state. | Organic letters 20081120 |
| The structure of a TNA-TNA complex in solution: NMR study of the octamer duplex derived from alpha-(L)-threofuranosyl-(3'-2')-CGAATTCG. | Journal of the American Chemical Society 20081112 |
| Ablation of AMP-activated protein kinase alpha2 activity exacerbates insulin resistance induced by high-fat feeding of mice. | Diabetes 20081101 |
| A CoMSIA study on the adenosine kinase inhibition of pyrrolo[2,3-d]pyrimidine nucleoside analogues. | Bioorganic & medicinal chemistry 20080501 |
| The polyglutamine-expanded protein ataxin-3 decreases bcl-2 mRNA stability. | Biochemical and biophysical research communications 20080111 |
| Beneficial effect of internal hydrogen bonding interactions on the beta-fragmentation of primary alkoxyl radicals. Two-step conversion of D-xylo- and D-ribofuranoses into L-threose and D-erythrose, respectively. | The Journal of organic chemistry 20071026 |
| Nicotinamide riboside kinase structures reveal new pathways to NAD+. | PLoS biology 20071001 |
| AMP kinase activation increases glucose uptake, decreases apoptosis, and improves pregnancy outcome in embryos exposed to high IGF-I concentrations. | Diabetes 20070901 |
| Mapping ligand interactions with the hyperpolarization activated cyclic nucleotide modulated (HCN) ion channel binding domain using a soluble construct. | Biochemistry 20070821 |
| Effects of adenosine monophosphate-activated kinase activators on bovine oocyte nuclear maturation in vitro. | Molecular reproduction and development 20070801 |
| 5-aminoimidazole-4-carboxamide 1-beta-D-ribofuranoside acutely stimulates skeletal muscle 2-deoxyglucose uptake in healthy men. | Diabetes 20070801 |
| Five- and six-membered conformationally locked 2',4'-carbocyclic ribo-thymidines: synthesis, structure, and biochemical studies. | Journal of the American Chemical Society 20070704 |
| Role of glycogen content in insulin resistance in human muscle cells. | Journal of cellular physiology 20070501 |
| Role of hypothalamic adenosine 5'-monophosphate-activated protein kinase in the impaired counterregulatory response induced by repetitive neuroglucopenia. | Endocrinology 20070301 |
| New pseudonucleosides containing chiral oxazolidin-2-ones and cyclosulfamides as aglycones: synthesis and antiviral evaluation. | Nucleosides, nucleotides & nucleic acids 20070101 |
| Bioactivity of glycogen phosphorylase inhibitors that bind to the purine nucleoside site. | Bioorganic & medicinal chemistry 20061201 |
| Stimulation of AMP-activated protein kinase is essential for the induction of drug metabolizing enzymes by phenobarbital in human and mouse liver. | Molecular pharmacology 20061201 |
| Induction of meiotic maturation in mouse oocytes by adenosine analogs. | Molecular reproduction and development 20060901 |
| Prolonged AMPK activation increases the expression of fatty acid transporters in cardiac myocytes and perfused hearts. | Molecular and cellular biochemistry 20060801 |
| 7-Deaza-2,8-diazaadenosine. | Acta crystallographica. Section C, Crystal structure communications 20060701 |
| Inhibition of lipid synthesis through activation of AMP kinase: an additional mechanism for the hypolipidemic effects of berberine. | Journal of lipid research 20060601 |
| Synthesis of 7-deoxypancratistatin from carbohydrates by the use of olefin metathesis. | Chemistry (Weinheim an der Bergstrasse, Germany) 20060412 |
| Genetic analysis of the capsular biosynthetic locus from all 90 pneumococcal serotypes. | PLoS genetics 20060301 |
| N8-(2'-O-methylribofuranosyl)-8-aza-7-deazaadenine monohydrate. | Acta crystallographica. Section C, Crystal structure communications 20060201 |
| Synthesis of 2'-C-difluoromethylribonucleosides and their enzymatic incorporation into oligonucleotides. | The Journal of organic chemistry 20050930 |
| Structural fluctuation and dynamics of ribose puckering in aqueous solution from first principles. | The journal of physical chemistry. B 20050707 |
| Circular hydrogen bond networks on the surface of beta-ribofuranose in aqueous solution. | The journal of physical chemistry. B 20050630 |
| Escherichia coli purine nucleoside phosphorylase II, the product of the xapA gene. | Journal of molecular biology 20050422 |
| 8-Aza-7-deaza-7-propynyladenosine methanol solvate. | Acta crystallographica. Section C, Crystal structure communications 20050401 |
| Increased potency and efficacy of combined phosphorylase inactivation and glucokinase activation in control of hepatocyte glycogen metabolism. | Diabetes 20050301 |
| MEK inhibitors block AICAR-induced maturation in mouse oocytes by a MAPK-independent mechanism. | Molecular reproduction and development 20050201 |
| Role of neuronal energy status in the regulation of adenosine 5'-monophosphate-activated protein kinase, orexigenic neuropeptides expression, and feeding behavior. | Endocrinology 20050101 |
| Design, synthesis, and antiviral evaluation of some polyhalogenated indole C-nucleosides. | Nucleosides, nucleotides & nucleic acids 20050101 |
| Activation of AMP-activated protein kinase inhibits protein synthesis associated with hypertrophy in the cardiac myocyte. | The Journal of biological chemistry 20040730 |
| NMR application probes a novel and ubiquitous family of enzymes that alter monosaccharide configuration. | The Journal of biological chemistry 20040611 |
| A glucose response element from the S. cerevisiae hexose transporter HXT1 gene is sensitive to glucose in human fibroblasts. | Journal of molecular biology 20040507 |
| Glucose 6-phosphate causes translocation of phosphorylase in hepatocytes and inactivates the enzyme synergistically with glucose. | The Biochemical journal 20040101 |
| Co-C bond dissociation energy and reaction volume change of 2',5'-dideoxyadenosylcobalamin studied by laser-induced time-resolved photoacoustic calorimetry. | Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20031001 |
| Structural determination of 5'-OH alpha-ribofuranoside modified cobalamins via 13C and DEPT NMR. | The Journal of organic chemistry 20030905 |
| A purL mutant of Sinorhizobium fredii HH103 is symbiotically defective and altered in its lipopolysaccharide. | Microbiology (Reading, England) 20030701 |
| Convergent synthesis of polyhalogenated quinoline C-nucleosides as potential antiviral agents. | The Journal of organic chemistry 20030530 |
| Ionic states of substrates and transition state analogues at the catalytic sites of N-ribosyltransferases. | Biochemistry 20030520 |
| Glucose regulates EF-2 phosphorylation and protein translation by a protein phosphatase-2A-dependent mechanism in INS-1-derived 832/13 cells. | The Journal of biological chemistry 20030516 |
| Synthesis of potent oxindole CDK2 inhibitors. | Bioorganic & medicinal chemistry 20030417 |
| 5-Aminoimidazole-4-carboxamide 1-beta -D-ribofuranoside (AICAR) stimulates myocardial glycogenolysis by allosteric mechanisms. | American journal of physiology. Regulatory, integrative and comparative physiology 20030401 |
| Regulation of glycogen synthase by glucose and glycogen: a possible role for AMP-activated protein kinase. | Diabetes 20030101 |
| [The synthesis and and study of cytotoxic activity of D-ribofuranosides and 2-deoxy-D-ribofuranosides of substituted bis(indolyl)furan, -pyrrole and indolo[2,3-alpha]carbazole derivatives]. | Bioorganicheskaia khimiia 20030101 |
| Bicyclo[3.2.1]amide-DNA: a chiral, nonchiroselective base-pairing system. | Chemistry (Weinheim an der Bergstrasse, Germany) 20021202 |
| Carbocyclic nucleosides (carbanucleosides) as new therapeutic leads. | Current topics in medicinal chemistry 20021001 |
| Synthesis of adenosylcobinamide 2-chlorophenyl phosphate, a zwitterionic cobinamide phosphate analog of adenosylcobalamin en route to crystallizable cobinamides. | Journal of inorganic biochemistry 20020815 |
| Acute and chronic treatment of ob/ob and db/db mice with AICAR decreases blood glucose concentrations. | Biochemical and biophysical research communications 20020621 |
| 3,4-Dihydro-6-methyl-3-beta-D-ribofuranosyl-4,5'-cyclo-9H-imidazo[1,2-a]purin-9-one hydrate. | Acta crystallographica. Section C, Crystal structure communications 20020301 |
| Pathways for alpha-D-ribose utilization for nucleobase salvage and 5-fluorouracil activation in rat brain. | Biochemical pharmacology 20020115 |
| Epstein-Barr virus encoded nuclear protein EBNA-3 binds a novel human uridine kinase/uracil phosphoribosyltransferase. | BMC cell biology 20020101 |
| Assignment of the liposidomycin diazepanone stereochemistry. | The Journal of organic chemistry 20010824 |
| Synthesis and cytotoxicity of 4'-C- and 5'-C-substituted toyocamycins. | Bioorganic & medicinal chemistry 20010101 |
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