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12650-69-0

12650-69-0 | L-talo-Non-2-enonic acid, 5,9-anhydro-2,3,4,8-tetradeoxy-8-[[(2S,3S)-3-[(1S,2S)-2-hydroxy-1-methylpropyl]oxiranyl]methyl]-3-methyl-, 8-carboxyoctyl ester, (2E)-

CAS No: 12650-69-0 Catalog No: AG000SV0 MDL No:MFCD01711620

Product Description

Catalog Number:
AG000SV0
Chemical Name:
L-talo-Non-2-enonic acid, 5,9-anhydro-2,3,4,8-tetradeoxy-8-[[(2S,3S)-3-[(1S,2S)-2-hydroxy-1-methylpropyl]oxiranyl]methyl]-3-methyl-, 8-carboxyoctyl ester, (2E)-
CAS Number:
12650-69-0
Molecular Formula:
C26H44O9
Molecular Weight:
500.6222
MDL Number:
MFCD01711620
IUPAC Name:
9-[(E)-4-[(2S,3R,4R,5S)-3,4-dihydroxy-5-[[(2S,3S)-3-[(2S,3S)-3-hydroxybutan-2-yl]oxiran-2-yl]methyl]oxan-2-yl]-3-methylbut-2-enoyl]oxynonanoic acid
InChI:
InChI=1S/C26H44O9/c1-16(13-23(30)33-11-9-7-5-4-6-8-10-22(28)29)12-20-25(32)24(31)19(15-34-20)14-21-26(35-21)17(2)18(3)27/h13,17-21,24-27,31-32H,4-12,14-15H2,1-3H3,(H,28,29)/b16-13+/t17-,18-,19-,20-,21-,24+,25-,26-/m0/s1
InChI Key:
MINDHVHHQZYEEK-HBBNESRFSA-N
SMILES:
OC(=O)CCCCCCCCOC(=O)/C=C(/C[C@@H]1OC[C@@H]([C@H]([C@H]1O)O)C[C@@H]1O[C@H]1[C@H]([C@@H](O)C)C)\C
EC Number:
603-145-3
UNII:
D0GX863OA5
NSC Number:
759182

Properties

Complexity:
694  
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
8  
Defined Bond Stereocenter Count:
1  
Exact Mass:
500.299g/mol
Formal Charge:
0
Heavy Atom Count:
35  
Hydrogen Bond Acceptor Count:
9  
Hydrogen Bond Donor Count:
4  
Isotope Atom Count:
0
Molecular Weight:
500.629g/mol
Monoisotopic Mass:
500.299g/mol
Rotatable Bond Count:
17  
Topological Polar Surface Area:
146A^2
Undefined Atom Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
XLogP3:
3  

Literature

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Intranasal mupirocin prophylaxis in elective surgery. A review of published studies. Chemotherapy 20080101
A randomized controlled trial comparing mupirocin versus Polysporin Triple for the prevention of catheter-related infections in peritoneal dialysis patients (the MP3 study). Peritoneal dialysis international : journal of the International Society for Peritoneal Dialysis 20080101
Microscopic and physiologic evidence for biofilm-associated wound colonization in vivo. Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society 20080101
Effects of commonly used topical antimicrobial agents on Acinetobacter baumannii: an in vitro study. Military medicine 20080101
Preoperative decolonization of methicillin-resistant Staphylococcus aureus. Orthopedics 20080101
A newborn with erythematous, desquamative plaques. Pediatric dermatology 20080101
Effect of once-a-week vs thrice-a-week application of mupirocin on methicillin and mupirocin resistance in peritoneal dialysis patients: three years of experience. Renal failure 20080101
In vitro antibacterial effects of topical local anesthetics. The Journal of dermatological treatment 20080101
Postoperative topical antimicrobial use. Dermatitis : contact, atopic, occupational, drug 20080101
An analysis of methods to prevent peritoneal dialysis catheter infections. Peritoneal dialysis international : journal of the International Society for Peritoneal Dialysis 20080101
A prospective study of the efficacy of local application of gentamicin versus mupirocin in the prevention of peritoneal dialysis catheter-related infections. Peritoneal dialysis international : journal of the International Society for Peritoneal Dialysis 20080101
Detection of methicillin and mupirocin resistance in staphylococcal hospital isolates with a touchdown multiplex polymerase chain reaction. Folia microbiologica 20080101
Distinctive features of foreskin condylomata acuminata associated with diabetes mellitus. Acta dermato-venereologica 20080101
Community-acquired methicillin-resistant Staphylococcus aureus infections in two scuba divers returning from the Philippines. Journal of travel medicine 20080101
The efficacy of topical antibiofilm agents in a sheep model of rhinosinusitis. American journal of rhinology 20080101
Does nasal colonization or mupirocin treatment affect recurrence of methicillin-resistant Staphylococcus aureus skin and skin structure infections? Infection control and hospital epidemiology 20071201
Implementation of an intensified infection control program to reduce MRSA transmissions in a German tertiary care hospital. American journal of infection control 20071201
Antimicrobial activity of mupirocin, daptomycin, linezolid, quinupristin/dalfopristin and tigecycline against vancomycin-resistant enterococci (VRE) from clinical isolates in Korea (1998 and 2005). Journal of biochemistry and molecular biology 20071130
Risk Factors for Methicillin-Resistant Staphylococcus aureus (MRSA) and Use of a Nasal Mupirocin Ointment in Oral Cancer Inpatients. Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons 20071101
Selective use of intranasal mupirocin and chlorhexidine bathing and the incidence of methicillin-resistant Staphylococcus aureus colonization and infection among intensive care unit patients. Infection control and hospital epidemiology 20071001
Management of a large healthcare-associated outbreak of Panton-Valentine leucocidin-positive meticillin-resistant Staphylococcus aureus in Germany. The Journal of hospital infection 20071001
Mupirocin resistance in patients colonized with methicillin-resistant Staphylococcus aureus in a surgical intensive care unit. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20070901
Generalized granuloma annulare and eruptive folliculitis in an HIV-positive man: resolution after antiretroviral therapy. Journal of the European Academy of Dermatology and Venereology : JEADV 20070901
Antibacterial activity of propolis against MRSA and synergism with topical mupirocin. Journal of alternative and complementary medicine (New York, N.Y.) 20070901
Value of whole-body washing with chlorhexidine for the eradication of methicillin-resistant Staphylococcus aureus: a randomized, placebo-controlled, double-blind clinical trial. Infection control and hospital epidemiology 20070901
Nasal carriage of meticillin resistant Staphylococcus aureus: the prevalence, patients at risk and the effect of elimination on outcomes among outclinic haemodialysis patients. European journal of medical research 20070726
Interpretive criteria to differentiate low- and high-level mupirocin resistance in Staphylococcus aureus. Journal of medical microbiology 20070701
Activities of clindamycin, synercid, telithromycin, linezolid, and mupirocin against Gram-positive coccal strains resistant to erythromycin in Korea. Archives of pharmacal research 20070701
Direct economic effect following mupirocin therapy failure among patients with uncomplicated skin and skin-structure infections in a large population-based cohort. Managed care interface 20070701
[Mupirocin resistance in methicillin-resistant Staphylococcus aureus strains isolated from wound infections]. Mikrobiyoloji bulteni 20070701
Successful termination of a furunculosis outbreak due to lukS-lukF-positive, methicillin-susceptible Staphylococcus aureus in a German village by stringent decolonization, 2002-2005. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20070601
Success of MRSA eradication in hospital routine: depends on compliance. Infection 20070601
Mupirocin H, a novel metabolite resulting from mutation of the HMG-CoA synthase analogue, mupH in Pseudomonas fluorescens. Chemical communications (Cambridge, England) 20070528
Mutational analysis reveals that all tailoring region genes are required for production of polyketide antibiotic mupirocin by pseudomonas fluorescens: pseudomonic acid B biosynthesis precedes pseudomonic acid A. The Journal of biological chemistry 20070525
Mupirocin resistance in Staphylococcus aureus in an Indian hospital. Diagnostic microbiology and infectious disease 20070501
Aminoacyl-tRNA synthetases: essential and still promising targets for new anti-infective agents. Expert opinion on investigational drugs 20070501
A neonatal specialist with recurrent methicillin-resistant Staphylococcus aureus (MRSA) carriage implicated in the transmission of MRSA to newborns. Infection control and hospital epidemiology 20070501
Multiple mechanisms to ameliorate the fitness burden of mupirocin resistance in Salmonella typhimurium. Molecular microbiology 20070501
Risk factors for isolation of low-level mupirocin-resistant versus -susceptible methicillin-resistant Staphylococcus aureus from patients in intensive care units. The Journal of infection 20070401
In vitro activity of lysostaphin, mupirocin, and tea tree oil against clinical methicillin-resistant Staphylococcus aureus. Diagnostic microbiology and infectious disease 20070401
[How promising is decontamination treatment of MRSA carriers?]. Medizinische Monatsschrift fur Pharmazeuten 20070301
Randomized controlled trial of chlorhexidine gluconate for washing, intranasal mupirocin, and rifampin and doxycycline versus no treatment for the eradication of methicillin-resistant Staphylococcus aureus colonization. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20070115
Interpretive criteria for mupirocin susceptibility testing of Staphylococcus spp. using CLSI guidelines. British journal of biomedical science 20070101
Prophylactic intranasal mupirocin ointment in the treatment of peritonitis in continuous ambulatory peritoneal dialysis patients. Advances in therapy 20070101
Comparison of protocols for surveillance of methicillin-resistant Staphylococcus aureus (MRSA): medical staff vs ICU patients. Annals of clinical and laboratory science 20070101
Stereoselective synthesis of methyl monate C. Organic letters 20061221
Preoperative use of mupirocin for the prevention of healthcare-associated Staphylococcus aureus infections: a cost-effectiveness analysis. Infection control and hospital epidemiology 20061201
Reduction of preoperative conjunctival bacterial flora with the use of mupirocin nasal ointment. Transactions of the American Ophthalmological Society 20061201
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Shark skin laceration. Dermatology online journal 20061031
[Prevention of peritonitis in patients with peritoneal dialysis]. Ugeskrift for laeger 20061023
Impact of treating Staphylococcus aureus nasal carriers on wound infections in cardiac surgery. The Journal of hospital infection 20061001
Skin colonization by Staphylococcus aureus in patients with eczema and atopic dermatitis and relevant combined topical therapy: a double-blind multicentre randomized controlled trial. The British journal of dermatology 20061001
Effectiveness of preemptive barrier precautions in controlling nosocomial colonization and infection by methicillin-resistant Staphylococcus aureus in a burn unit. American journal of infection control 20061001
Molecular analysis of isoleucyl-tRNA synthetase mutations in clinical isolates of methicillin-resistant Staphylococcus aureus with low-level mupirocin resistance. Journal of Korean medical science 20061001
[Onycholysis with hyponychium exudate secondary to chemotherapy with paclitaxel and capecitabine]. Actas dermo-sifiliograficas 20061001
Impact of prophylactic mupirocin for radical esophagectomy. Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy 20061001
Long-term efficacy of mupirocin in the prevention of infections with meticillin-resistant Staphylococcus aureus in a gastroenterology unit. The Journal of hospital infection 20060801
Randomized clinical trial of the effect of applying ointment to surgical wounds before occlusive dressing. The British journal of surgery 20060801
Antimicrobial and toxicological profile of the new biocide Akacid plus. The Journal of antimicrobial chemotherapy 20060701
Laboratory-acquired meticillin-resistant Staphylococcus aureus (MRSA) in two microbiology laboratory technicians. European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology 20060701
Total nipple-areola complex necrosis in inferior pedicle breast reduction. Plastic and reconstructive surgery 20060701
Safety of targeted perioperative mupirocin treatment for preventing infections after cardiac surgery. The Annals of thoracic surgery 20060601
Managing methicillin-resistant staphylococci: a paradigm for preventing nosocomial transmission of resistant organisms. The American journal of medicine 20060601
[Positive screening for MRSA--clinical consequences?]. Der Unfallchirurg 20060601
Antibiotic lock technique reduces the incidence of temporary catheter-related infections. Clinical nephrology 20060601
Microsphere-based protease assays and screening application for lethal factor and factor Xa. Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501
Enhanced activity of rifalazil in combination with levofloxacin, linezolid, or mupirocin against Staphylococcus aureus in vitro. The Journal of antibiotics 20060501
An outbreak of methicillin-resistant Staphylococcus aureus skin infections resulting from horse to human transmission in a veterinary hospital. Veterinary microbiology 20060416
A study of senior staff nurses' perceptions about MRSA. Nursing times 20060401
Antibacterial, partially acetylated oligorhamnosides from Cleistopholis patens. Journal of natural products 20060401
Surveillance for mupirocin resistance following introduction of routine peri-operative prophylaxis with nasal mupirocin. The Journal of hospital infection 20060301
Prevalence of nasal carriage of Staphylococcus aureus and susceptibility of isolates to methicillin and mupirocin among healthcare workers in an Iranian Hospital. Infection control and hospital epidemiology 20060301
Decrease in the incidence of mupirocin resistance among methicillin-resistant Staphylococcus aureus in carriers from an intensive care unit. American journal of infection control 20060201
Controlling the usage of intranasal mupirocin does impact the rate of Staphylococcus aureus deep sternal wound infections in cardiac surgery patients. American journal of infection control 20060201
Neonatal eosinophilic pustulosis. International journal of dermatology 20060201
Reduction in incidence of nosocomial methicillin-resistant Staphylococcus aureus (MRSA) infection in an intensive care unit: role of treatment with mupirocin ointment and chlorhexidine baths for nasal carriers of MRSA. Infection control and hospital epidemiology 20060201
[Impetigo]. Annales de dermatologie et de venereologie 20060201
Treatment of chronic rhinosinusitis exacerbations due to methicillin-resistant Staphylococcus aureus with mupirocin irrigations. American journal of otolaryngology 20060101
[About the article 'What's new in dermatology?']. Annales de dermatologie et de venereologie 20060101
Spotlight on targeting aminoacyl-tRNA synthetases for the treatment of fungal infections. Drug news & perspectives 20060101
In vivo transfer of high-level mupirocin resistance from Staphylococcus epidermidis to methicillin-resistant Staphylococcus aureus associated with failure of mupirocin prophylaxis. The Journal of antimicrobial chemotherapy 20051201
Elimination of a community-acquired methicillin-resistant Staphylococcus aureus infection in a nurse with atopic dermatitis. Archives of dermatology 20051201
Air, hair, knees, nose. Infection control and hospital epidemiology 20051201
Perioperative intranasal mupirocin for the prevention of surgical-site infections: systematic review of the literature and meta-analysis. Infection control and hospital epidemiology 20051201
Incidence and effect of incorrect prescription and administration of nasal mupirocin for methicillin-resistant Staphylococcus aureus. The Journal of hospital infection 20051001
The impact of topical mupirocin on peritoneal dialysis infection in Singapore General Hospital. Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20051001
Current options for the treatment of impetigo in children. Expert opinion on pharmacotherapy 20051001
Effects of mupirocin at subinhibitory concentrations on biofilm formation in Pseudomonas aeruginosa. Chemotherapy 20051001
Unselective use of intranasal mupirocin ointment for controlling propagation of methicillin-resistant Staphylococcus aureus in a thoracic surgery ward. Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy 20051001
Community-acquired methicillin-resistant Staphylococcus aureus outbreak in a local high school football team unsuccessful interventions. The Pediatric infectious disease journal 20050901
The impact of topical mupirocin on peritoneal dialysis infection rates in Singapore General Hospital. Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20050801
Decrease in Staphylococcus aureus surgical site infections following cardiovascular surgery. The Journal of hospital infection 20050701
Shift to Pseudomonic acid B production in P. fluorescens NCIMB10586 by mutation of mupirocin tailoring genes mupO, mupU, mupV, and macpE. Chemistry & biology 20050701
Mupirocin for controlling methicillin-resistant Staphylococcus aureus: lessons from a decade of use at a university hospital. Infection control and hospital epidemiology 20050701
Prediction of genotoxicity of chemical compounds by statistical learning methods. Chemical research in toxicology 20050601
Temporary hemodialysis catheters as a long-term vascular access in chronic hemodialysis patients. Therapeutic apheresis and dialysis : official peer-reviewed journal of the International Society for Apheresis, the Japanese Society for Apheresis, the Japanese Society for Dialysis Therapy 20050601
Randomized, controlled trial of topical exit-site application of honey (Medihoney) versus mupirocin for the prevention of catheter-associated infections in hemodialysis patients. Journal of the American Society of Nephrology : JASN 20050501
Mupirocin W, a novel pseudomonic acid produced by targeted mutation of the mupirocin biosynthetic gene cluster. Chemical communications (Cambridge, England) 20050307
Catalytic asymmetric synthesis of a potent thiomarinol antibiotic. Journal of the American Chemical Society 20050216
Randomized, double-blind trial of antibiotic exit site cream for prevention of exit site infection in peritoneal dialysis patients. Journal of the American Society of Nephrology : JASN 20050201
Prevention of acquired infections in intubated patients with the combination of two decontamination regimens. Critical care medicine 20050201
Detection and treatment of antibiotic-resistant bacterial carriage in a surgical intensive care unit: a 6-year prospective survey. Infection control and hospital epidemiology 20050201
Staphylococcus aureus decolonization. The Pediatric infectious disease journal 20050101
Mupirocin once weekly reduces the incidence of catheter exit-site infection in peritoneal dialysis patients. Peritoneal dialysis international : journal of the International Society for Peritoneal Dialysis 20050101
Use of intranasal mupirocin to prevent methicillin-resistant Staphylococcus aureus infection in intensive care units. Critical care (London, England) 20050101
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Bifidobacterium-selective isolation and enumeration from chicken caeca by a modified oligosaccharide antibiotic-selective agar medium. Letters in applied microbiology 20050101
Effect of local mupirocin application on exit-site infection and peritonitis in an Indian peritoneal dialysis population. Peritoneal dialysis international : journal of the International Society for Peritoneal Dialysis 20050101
Treatment of uncomplicated skin and skin structure infections in the diabetic patient. Journal of drugs in dermatology : JDD 20050101
Efficacy and safety of combination ointment 'fluticasone propionate 0.005% plus mupirocin 2.0%' for the treatment of atopic dermatitis with clinical suspicion of secondary bacterial infection: an open label uncontrolled study. Indian journal of dermatology, venereology and leprology 20050101
Routine use of mupirocin at the peritoneal catheter exit site and mupirocin resistance: still low after 7 years. Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20041201
Dialysis catheter-related bacteremia: treatment and prophylaxis. American journal of kidney diseases : the official journal of the National Kidney Foundation 20041101
Heart transplantation in a patient with a left ventricular assist device and methicillin-resistant Staphylococcus aureus infection. The Annals of thoracic surgery 20041101
Cases from the aerospace medicine residents' teaching file: furunculosis. Aviation, space, and environmental medicine 20041101
[Perioperative nosocomial infection preventive measures]. Nihon Geka Gakkai zasshi 20041101
Treatment of impetigo: save mupirocin. BMJ (Clinical research ed.) 20041023
Antimicrobial agents for preventing peritonitis in peritoneal dialysis patients. The Cochrane database of systematic reviews 20041018
Stamping out Staphylococcus. Clinical immunology (Orlando, Fla.) 20041001
The CARI guidelines. Evidence for peritonitis treatment and prophylaxis: prophylaxis for exit site/tunnel infections using mupirocin. Nephrology (Carlton, Vic.) 20041001
Oxacillin- and mupirocin-resistant Staphylococcus aureus: in vitro activity of silver sulphadiazine and cerium nitrate in hospital strains. Journal of chemotherapy (Florence, Italy) 20041001
Synergistic effects of mupirocin and an isoflavanone isolated from Erythrina variegata on growth and recovery of methicillin-resistant Staphylococcus aureus. International journal of antimicrobial agents 20040901
Staphylococcus aureus nasal carriage in patients on haemodialysis: role of cutaneous colonization. The Journal of hospital infection 20040901
Decrease in Staphylococcus aureus surgical-site infection rates after orthopaedic surgery after intranasal mupirocin ointment. The Journal of hospital infection 20040901
Anti-staphylococcal activity of indolmycin, a potential topical agent for control of staphylococcal infections. The Journal of antimicrobial chemotherapy 20040801
Activity of mupirocin and 14 additional antibiotics against staphylococci isolated from Latin American hospitals: report from the SENTRY antimicrobial surveillance program. Journal of chemotherapy (Florence, Italy) 20040801
Unique approaches for the topical treatment and prevention of cutaneous infections: report from a clinical roundtable. Cutis 20040801
Topical mupirocin and catheter-related bacteremia. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20040601
Prevalence of mupirocin resistance in clinical isolates of Staphylococcus aureus and Staphylococcus epidermidis: results of the Antimicrobial Resistance Surveillance Study of the Paul-Ehrlich-Society for Chemotherapy, 2001. International journal of antimicrobial agents 20040601
Evaluation of surgical-site infections following cardiovascular surgery. Infection control and hospital epidemiology 20040601
Is the burden of Staphylococcus aureus among patients with surgical-site infections growing? Infection control and hospital epidemiology 20040601
Preoperative risk factors for nasal carriage of Staphylococcus aureus. Infection control and hospital epidemiology 20040601
Improving outcomes of coronary artery bypass graft infections with multiple interventions: putting science and data to the test. Infection control and hospital epidemiology 20040601
In vitro activity of mupirocin and amoxicillin-clavulanate alone and in combination against staphylococci including those resistant to methicillin. International journal of antimicrobial agents 20040501
The evaluation of a mupirocin-based selective medium for the enumeration of bifidobacteria from probiotic animal feed. Journal of microbiological methods 20040401
Control of endemic MRSA-what is the evidence? A personal view. The Journal of hospital infection 20040401
A randomized, controlled trial of tea tree topical preparations versus a standard topical regimen for the clearance of MRSA colonization. The Journal of hospital infection 20040401
Mupirocin prophylaxis against nosocomial Staphylococcus aureus infections in nonsurgical patients: a randomized study. Annals of internal medicine 20040316
Mupirocin prophylaxis misses by a nose. Annals of internal medicine 20040316
Summaries for patients. Effects of antibiotic nose ointment for hospitalized patients with Staphylococcus aureus. Annals of internal medicine 20040316
Simultaneous PCR detection of ica cluster and methicillin and mupirocin resistance genes in catheter-isolated Staphylococcus. International microbiology : the official journal of the Spanish Society for Microbiology 20040301
Rapid control of an outbreak of Staphylococcus aureus on a neonatal intensive care department using standard infection control practices and nasal mupirocin. American journal of infection control 20040201
Clonal dissemination of mupirocin-resistant staphylococci in Greek hospitals. The Journal of antimicrobial chemotherapy 20040101
The isoleucyl-tRNA synthetase mutation V588F conferring mupirocin resistance in glycopeptide-intermediate Staphylococcus aureus is not associated with a significant fitness burden. The Journal of antimicrobial chemotherapy 20040101
A prospective, randomized pilot evaluation of topical triple antibiotic versus mupirocin for the prevention of uncomplicated soft tissue wound infection. The American journal of emergency medicine 20040101
Furunculosis and IgG subclass deficiency. Dermatology (Basel, Switzerland) 20040101
Molecular epidemiology and control of nosocomial methicillin-resistant Staphylococcus aureus infection in a teaching hospital. Journal of the Formosan Medical Association = Taiwan yi zhi 20040101
Panton-valentine leukocidin and staphyloccoccal skin infections in schoolchildren. Emerging infectious diseases 20040101
[Optimal choice of antibiotic for local use in patients with external otitis and furuncles in the acoustic meatus]. Vestnik otorinolaringologii 20040101
Plasmids of Staphylococcus cohnii isolated from the intensive-care unit. Folia microbiologica 20040101
Antibacterial activity of a new, stable, aqueous extract of allicin against methicillin-resistant Staphylococcus aureus. British journal of biomedical science 20040101
Decrease in infections with the introduction of mupirocin cream at the peritoneal dialysis catheter exit site. Journal of nephrology 20040101
The effects of once- or thrice-weekly mupirocin application on mupirocin resistance in patients on continuous ambulatory peritoneal dialysis--first 6 months' experience. Advances in peritoneal dialysis. Conference on Peritoneal Dialysis 20040101
Emergence of resistance in staphylococci after long-term mupirocin application in patients on continuous ambulatory peritoneal dialysis. Advances in peritoneal dialysis. Conference on Peritoneal Dialysis 20040101
[Occurrence of high-level mupirocin resistant coagulase-negative staphylococci in hospitals and their characterization]. Medycyna doswiadczalna i mikrobiologia 20040101
[Antibiotic sensitivity of Corynebacterium amycolatum]. Medycyna doswiadczalna i mikrobiologia 20040101
Mupirocin prophylaxis to prevent Staphylococcus aureus infection in patients undergoing dialysis: a meta-analysis. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20031215
Mupirocin-based decolonization of Staphylococcus aureus carriers in residents of 2 long-term care facilities: a randomized, double-blind, placebo-controlled trial. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20031201
Treatment for impetigo. The British journal of general practice : the journal of the Royal College of General Practitioners 20031201
Prophylaxis against gram-positive organisms causing exit-site infection and peritonitis in continuous ambulatory peritoneal dialysis patients by applying mupirocin ointment at the catheter exit site. Peritoneal dialysis international : journal of the International Society for Peritoneal Dialysis 20031201
Development and validation of a liquid chromatographic method for in vitro mupirocin quantification in both skin layers and percutaneous penetration studies. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20031105
Prevention of Staphylococcus aureus infections among surgical patients: beyond traditional perioperative prophylaxis. Surgery 20031101
Experience in prevention of sternal wound infections in nasal carriers of Staphylococcus aureus. Surgery 20031101
Treatment of Staphylococcus aureus colonization and prophylaxis for infection with topical intranasal mupirocin: an evidence-based review. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20031001
Structural changes in silicon rubber peritoneal dialysis catheters in patients using mupirocin at the exit site. The International journal of artificial organs 20031001
Randomized clinical trial of preoperative intranasal mupirocin to reduce surgical-site infection after digestive surgery. The British journal of surgery 20030901
Immediate control of a methicillin-resistant Staphylococcus aureus outbreak in a neonatal intensive care unit. Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy 20030901
Neonatal pemphigus foliaceus. Journal of the American Academy of Dermatology 20030801
Methicillin-resistant Staphylococcus aureus whole-body decolonization among hospitalized patients with variable site colonization by using mupirocin in combination with octenidine dihydrochloride. The Journal of hospital infection 20030801
How does Pseudomonas fluorescens avoid suicide from its antibiotic pseudomonic acid?: Evidence for two evolutionarily distinct isoleucyl-tRNA synthetases conferring self-defense. The Journal of biological chemistry 20030711
The preventive effects of mupirocin against nasotracheal intubation-related bacterial carriage. Anesthesia and analgesia 20030701
Use of perioperative mupirocin to prevent methicillin-resistant Staphylococcus aureus (MRSA) orthopaedic surgical site infections. The Journal of hospital infection 20030701
Toxic epidermal necrolysis after topical intranasal application of mupirocin. Infection control and hospital epidemiology 20030601
[Use of nasal mupirocin for Staphylococcus aureus: effect on nasal carriers and nosocomial infections]. Biomedica : revista del Instituto Nacional de Salud 20030601
A systematic review and meta-analysis of treatments for impetigo. The British journal of general practice : the journal of the Royal College of General Practitioners 20030601
[Two hospital staff with throat carriage of methicillin-resistant Staphylococcus aureus, which had to be treated with systemic antibiotics]. Nederlands tijdschrift voor geneeskunde 20030531
A chromosomal location of the mupA gene in Staphylococcus aureus expressing high-level mupirocin resistance. The Journal of antimicrobial chemotherapy 20030501
Effects of mupirocin at subinhibitory concentrations on flagella formation in Pseudomonas aeruginosa and Proteus mirabilis. The Journal of antimicrobial chemotherapy 20030501
Survey of high- and low-level mupirocin-resistant strains of methicillin-resistant Staphylococcus aureus in 15 Japanese hospitals. Chemotherapy 20030501
Improvement of mupirocin E-test for susceptibility testing of Staphylococcus aureus. Journal of medical microbiology 20030501
First report of clinical and microbiological failure in the eradication of glycopeptide-intermediate methicillin-resistant Staphylococcus aureus carriage by mupirocin. European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology 20030501
Aminoacyl-tRNA synthetases and their inhibitors as a novel family of antibiotics. Applied microbiology and biotechnology 20030501
Characterization of the mupirocin biosynthesis gene cluster from Pseudomonas fluorescens NCIMB 10586. Chemistry & biology 20030501
Predictive value and cost-effectiveness analysis of a rapid polymerase chain reaction for preoperative detection of nasal carriage of Staphylococcus aureus. Infection control and hospital epidemiology 20030501
Mupirocin-resistant, methicillin-resistant Staphylococcus aureus: does mupirocin remain effective? Infection control and hospital epidemiology 20030501
Short-term effects of topical fusidic acid or mupirocin on the prevalence of fusidic acid resistant (FusR) Staphylococcus aureus in atopic eczema. The British journal of dermatology 20030501
Mupirocin resistance in clinical isolates of Staphylococcus aureus. Infection control and hospital epidemiology 20030401
Mupirocin and Staphylococcus aureus: a recent paradigm of emerging antibiotic resistance. The Journal of antimicrobial chemotherapy 20030301
Prevalence and mechanisms of low- and high-level mupirocin resistance in staphylococci isolated from a Korean hospital. The Journal of antimicrobial chemotherapy 20030301
[Pulsed-field gel electrophoresis type and antimicrobial susceptibility of arbekacin mupirocin and teicoplanin resistant methicillin-resistant Staphylococcus aureus]. Kansenshogaku zasshi. The Journal of the Japanese Association for Infectious Diseases 20030201
Lack of efficacy of mupirocin in the prevention of infections with Staphylococcus aureus in liver transplant recipients and candidates. Transplantation 20030127
Asymptomatic nasal carriage of mupirocin-resistant, methicillin-resistant Staphylococcus aureus (MRSA) in a pet dog associated with MRSA infection in household contacts. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20030115
Comparison of silver sulfadiazine 1%, mupirocin 2%, and fusidic acid 2% for topical antibacterial effect in methicillin-resistant staphylococci-infected, full-skin thickness rat burn wounds. The Journal of burn care & rehabilitation 20030101
Topical antimicrobial agents in dermatology. Clinics in dermatology 20030101
Reducing peritonitis rates in a peritoneal dialysis program of indigent ethnic minorities. Peritoneal dialysis international : journal of the International Society for Peritoneal Dialysis 20030101
Susceptibility of skin and soft-tissue isolates of Staphylococcus aureus and Streptococcus pyogenes to topical antibiotics: indications of clonal spread of fusidic acid-resistant Staphylococcus aureus. Scandinavian journal of infectious diseases 20030101
Preventing postoperative Staphylococcus infections: an update. Surgical technology international 20030101
Intranasal mupirocin does not prevent exit-site infections in children receiving peritoneal dialysis. Peritoneal dialysis international : journal of the International Society for Peritoneal Dialysis 20030101
Comparative study of mupirocin and sodium fucidate in the prophylaxis of exit-site infections in CAPD patients. Peritoneal dialysis international : journal of the International Society for Peritoneal Dialysis 20030101
The effects of weekly mupirocin application on infections in continuous ambulatory peritoneal dialysis patients. Advances in peritoneal dialysis. Conference on Peritoneal Dialysis 20030101
[Mupirocin: prophylaxis of hospital-acquired infections due to Staphylococcus aureus and sanitation of hospital environment]. Antibiotiki i khimioterapiia = Antibiotics and chemoterapy [sic] 20030101
A clinical trial of mupirocin in the eradication of methicillin-resistant Staphylococcus aureus nasal carriage in a digestive disease unit. The Journal of hospital infection 20021201
Analysis of rILERS, an isoleucyl-tRNA synthetase gene associated with mupirocin production by Pseudomonas fluorescens NCIMB 10586. DNA sequence : the journal of DNA sequencing and mapping 20021201
[Mupirocin in the prevention of surgical wound infection caused by Staphylococcus aureus]. Ugeskrift for laeger 20021111
Effectiveness of mupirocin and polymyxin B in experimental Staphylococcus aureus, Pseudomonas aeruginosa, and Serratia marcescens keratitis. Cornea 20021101
Process improvement plan for the reduction of sternal surgical site infections among patients undergoing coronary artery bypass graft surgery. American journal of infection control 20021101
Intranasal mupirocin to prevent postoperative infections. The New England journal of medicine 20021010
Intranasal mupirocin to prevent postoperative infections. The New England journal of medicine 20021010
A randomized controlled trial of topical exit site mupirocin application in patients with tunnelled, cuffed haemodialysis catheters. Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20021001
Detection of methicillin and mupirocin resistance in Staphylococcus aureus isolates using conventional and molecular methods: a descriptive study from a burns unit with high prevalence of MRSA. Journal of clinical pathology 20021001
Decolonization of methicillin-resistant Staphylococcus aureus using oral vancomycin and topical mupirocin. Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases 20021001
Toxic epidermal necrolysis due to administration of celecoxib (Celebrex). Southern medical journal 20021001
Surgical site infections in orthopedic surgery: the effect of mupirocin nasal ointment in a double-blind, randomized, placebo-controlled study. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20020815
In vitro activity of linezolid, quinupristin-dalfopristin, vancomycin, teicoplanin, moxifloxacin and mupirocin against methicillin-resistant Staphylococcus aureus: comparative evaluation by the E test and a broth microdilution method. Diagnostic microbiology and infectious disease 20020801
Mupirocin vs terbinafine in impetigo. Indian journal of pediatrics 20020801
Intranasal mupirocin to prevent postoperative Staphylococcus aureus infections. The New England journal of medicine 20020613
Mupirocin to prevent S. aureus infections. The New England journal of medicine 20020613
Preventing Staphylococcus aureus infection in the renal unit. QJM : monthly journal of the Association of Physicians 20020601
Mupirocin resistance in methicillin-resistant Staphylococcus aureus clinical isolates in a Spanish hospital. Co-application of multiplex PCR assay and conventional microbiology methods. Diagnostic microbiology and infectious disease 20020601
Nosocomial transmission of methicillin-resistant Staphylococcus aureus from a mother to her preterm quadruplet infants. American journal of infection control 20020501
Emerging elevated mupirocin resistance rates among staphylococcal isolates in the SENTRY Antimicrobial Surveillance Program (2000): correlations of results from disk diffusion, Etest and reference dilution methods. Diagnostic microbiology and infectious disease 20020401
The effect of antibiotic treatment on the intracellular nucleotide pools of Staphylococcus aureus. FEMS microbiology letters 20020305
The bioavailability of mupirocin in nasal secretions in vitro. Journal of clinical pathology 20020301
Simultaneous detection of the mecA and ileS-2 genes in coagulase-negative staphylococci isolated from Brazilian hospitals by multiplex PCR. Diagnostic microbiology and infectious disease 20020301
Folliculitis decalvans: successful treatment with a combination of rifampicin and topical mupirocin. The Journal of dermatology 20020301
Mupirocin resistance after long-term use for Staphylococcus aureus colonization in patients undergoing chronic peritoneal dialysis. American journal of kidney diseases : the official journal of the National Kidney Foundation 20020201
A comparison of the efficacy and safety of mupirocin cream and cephalexin in the treatment of secondarily infected eczema. Clinical and experimental dermatology 20020101
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Spontaneous peritoneal catheter extrusion. Peritoneal dialysis international : journal of the International Society for Peritoneal Dialysis 20020101
[Efficient antibiotic therapy in radical surgery on the maxillary sinus]. Vestnik otorinolaringologii 20020101
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[Topical antibiotics and clinical use]. Mikrobiyoloji bulteni 20020101
Structural basis for the recognition of isoleucyl-adenylate and an antibiotic, mupirocin, by isoleucyl-tRNA synthetase. The Journal of biological chemistry 20011214
The spread of a mupirocin-resistant/methicillin-resistant Staphylococcus aureus clone in Kuwait hospitals. Acta tropica 20011022
Genetic analysis of methicillin-resistant Staphylococcus aureus expressing high- and low-level mupirocin resistance. Journal of medical microbiology 20011001
Mupirocin resistance in Staphylococcus aureus from Greek hospitals. International journal of antimicrobial agents 20011001
Prevention of catheter related infections in patients on CAPD. The International journal of artificial organs 20011001
Determinants of Staphylococcus aureus nasal carriage. The Netherlands journal of medicine 20010901
Reduction in gram-positive pneumonia and antibiotic consumption following the use of a SDD protocol including nasal and oral mupirocin. European journal of emergency medicine : official journal of the European Society for Emergency Medicine 20010901
Topical mupirocin for eradication of MRSA colonization with mupirocin-resistant strains. Infection control and hospital epidemiology 20010901
Prophylaxis against Staphylococcus aureus vascular graft infection with mupirocin-soaked, collagen-sealed dacron. The Journal of surgical research 20010801
Quorum-sensing-dependent regulation of biosynthesis of the polyketide antibiotic mupirocin in Pseudomonas fluorescens NCIMB 10586. Microbiology (Reading, England) 20010801
MRSA patients: proven methods to treat colonization and infection. The Journal of hospital infection 20010801
Association between nasal methicillin-resistant Staphylococcus aureus carriage and infection in liver transplant recipients. Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society 20010801
Persistence of a clone of methicillin-resistant Staphylococcus aureus in a burns unit. Journal of medical microbiology 20010601
Mupirocin resistance among Malaysian isolates of methicillin-resistant Staphylococcus aureus. International journal of antimicrobial agents 20010501
Intranasal mupirocin reduces sternal wound infection after open heart surgery in diabetics and nondiabetics. The Annals of thoracic surgery 20010501
Emergence and spread of low-level mupirocin resistance in methicillin-resistant Staphylococcus aureus isolated from a community hospital in Japan. The Journal of hospital infection 20010401
[Mupirocin resistant MRSA in Japan]. Nihon rinsho. Japanese journal of clinical medicine 20010401
Differentiating the biosynthesis of pseudomonic acids A and B. The Journal of antibiotics 20010201
[Detection of mupirocin resistant staphylococci from patients treated with mupirocin]. Kansenshogaku zasshi. The Journal of the Japanese Association for Infectious Diseases 20010101
Effect of preventing Staphylococcus aureus carriage on rates of peritoneal catheter-related staphylococcal infections. Literature synthesis. Peritoneal dialysis international : journal of the International Society for Peritoneal Dialysis 20010101
Local application of mupirocin at the peritoneal catheter exit site prevents early postoperative infections and should become standard practice. Peritoneal dialysis international : journal of the International Society for Peritoneal Dialysis 20010101
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