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Home > Indoles and Oxindole > 125314-64-9
CAS No: 125314-64-9 Catalog No: AG000NHG MDL No:
Title | Journal |
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Novel Nrf2/ARE activator, trans-Coniferylaldehyde, induces a HO-1-mediated defense mechanism through a dual p38α/MAPKAPK-2 and PK-N3 signaling pathway. | Chemical research in toxicology 20150921 |
The E3 ubiquitin ligase Trim7 mediates c-Jun/AP-1 activation by Ras signalling. | Nature communications 20150101 |
[Protein kinase C mediates thrombin-induced monocyte chemoattractant protein-1 release from human lung fibroblasts]. | Nan fang yi ke da xue xue bao = Journal of Southern Medical University 20120901 |
Regulation of the alternative splicing of sarcoplasmic reticulum Ca²⁺-ATPase1 (SERCA1) by phorbol 12-myristate 13-acetate (PMA) via a PKC pathway. | Biochemical and biophysical research communications 20120629 |
Regulation of hippocampal long-term potentiation and long-term depression by diacylglycerol kinase ζ. | Hippocampus 20120501 |
MAPK- and PKC/CREB-dependent induction of interleukin-11 by the environmental contaminant formaldehyde in human bronchial epithelial cells. | Toxicology 20120206 |
Characterization of the cellular action of the MSK inhibitor SB-747651A. | The Biochemical journal 20120101 |
[Identification of signal transduction pathway in fresh and vitrified porcine oocytes]. | Tsitologiia 20120101 |
Targeting sphingosine kinase 1 in carcinoma cells decreases proliferation and survival by compromising PKC activity and cytokinesis. | PloS one 20120101 |
Molecular investigation of the effects of lindane in rat hepatocytes: microarray and mechanistic studies. | Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20111201 |
Distinct roles for Rap1b protein in platelet secretion and integrin αIIbβ3 outside-in signaling. | The Journal of biological chemistry 20111111 |
Parathyroid hormone and the regulation of cell cycle in colon adenocarcinoma cells. | Biochimica et biophysica acta 20111001 |
Inhibition of protein kinase C promotes differentiation of neuroblastoma × glioma NG108-15 hybrid cells. | The European journal of neuroscience 20111001 |
All-trans retinoic acid and a novel synthetic retinoid tamibarotene (Am80) differentially regulate CD38 expression in human leukemia HL-60 cells: possible involvement of protein kinase C-delta. | Journal of leukocyte biology 20110801 |
Nitric oxide is an activity-dependent regulator of target neuron intrinsic excitability. | Neuron 20110728 |
Submaximal inhibition of protein kinase C restores ADP-induced dense granule secretion in platelets in the presence of Ca2+. | The Journal of biological chemistry 20110617 |
Synthesis and biological activity of splitomicin analogs targeted at human NAD(+)-dependent histone deacetylases (sirtuins). | Bioorganic & medicinal chemistry 20110615 |
PKC and PTPα participate in Src activation by 1α,25OH2 vitamin D3 in C2C12 skeletal muscle cells. | Molecular and cellular endocrinology 20110606 |
SHAFTS: a hybrid approach for 3D molecular similarity calculation. 2. Prospective case study in the discovery of diverse p90 ribosomal S6 protein kinase 2 inhibitors to suppress cell migration. | Journal of medicinal chemistry 20110526 |
Somatic depolarization enhances GABA release in cerebellar interneurons via a calcium/protein kinase C pathway. | The Journal of neuroscience : the official journal of the Society for Neuroscience 20110413 |
Insulin up-regulates heme oxygenase-1 expression in 3T3-L1 adipocytes via PI3-kinase- and PKC-dependent pathways and heme oxygenase-1-associated microRNA downregulation. | Endocrinology 20110201 |
PKC inhibitors RO 31-8220 and Gö 6983 enhance epinephrine-induced platelet aggregation in catecholamine hypo-responsive platelets by enhancing Akt phosphorylation. | BMB reports 20110201 |
Effects of gomisin A on vascular contraction in rat aortic rings. | Naunyn-Schmiedeberg's archives of pharmacology 20110101 |
Differential inhibitor sensitivity between human kinases VRK1 and VRK2. | PloS one 20110101 |
M-CSF induces monocyte survival by activating NF-κB p65 phosphorylation at Ser276 via protein kinase C. | PloS one 20110101 |
Action potential bursts in central snail neurons elicited by paeonol: roles of ionic currents. | Acta pharmacologica Sinica 20101201 |
Expression of CD203c and CD63 in human basophils: relationship to differential regulation of piecemeal and anaphylactic degranulation processes. | Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 20100901 |
Chitinase induce the release of IL-8 in human airway epithelial cells, via Ca2+-dependent PKC and ERK pathways. | Scandinavian journal of immunology 20100701 |
The ceramide-1-phosphate analogue PCERA-1 modulates tumour necrosis factor-alpha and interleukin-10 production in macrophages via the cAMP-PKA-CREB pathway in a GTP-dependent manner. | Immunology 20100301 |
Novel 3-arylideneindolin-2-ones as inhibitors of NAD+ -dependent histone deacetylases (sirtuins). | Journal of medicinal chemistry 20100211 |
Involvement of phosphatidylcholine-phospholipase C and protein kinase C in peptidoglycan-induced nuclear factor-kappaB activation and cyclooxygenase-2 expression in RAW 264.7 macrophages. | Pharmacological research 20100201 |
Protein kinase C epsilon is involved in ionizing radiation induced bystander response in human cells. | The international journal of biochemistry & cell biology 20091201 |
Nitro-aspirin inhibits MCF-7 breast cancer cell growth: effects on COX-2 expression and Wnt/beta-catenin/TCF-4 signaling. | Biochemical pharmacology 20091115 |
Identification and characterization of novel sirtuin inhibitor scaffolds. | Bioorganic & medicinal chemistry 20091001 |
[Fast nongenomic aldosterone effect on the kinetics of intracellular sodium and cell volume in the cortical part of collecting ducts of the rat kidney]. | Rossiiskii fiziologicheskii zhurnal imeni I.M. Sechenova 20090801 |
Periadventitial adipose tissue impairs coronary endothelial function via PKC-beta-dependent phosphorylation of nitric oxide synthase. | American journal of physiology. Heart and circulatory physiology 20090701 |
Fragment and knowledge-based design of selective GSK-3beta inhibitors using virtual screening models. | European journal of medicinal chemistry 20090601 |
Mechanism of action of the stimulatory effect of apigenin-6-C-(2''-O-alpha-l-rhamnopyranosyl)-beta-L-fucopyranoside on 14C-glucose uptake. | Chemico-biological interactions 20090515 |
The PKC inhibitor Ro31-8220 blocks acute amphetamine-induced dopamine overflow in the nucleus accumbens. | Neuroscience letters 20090515 |
IL-17F-induced IL-11 release in bronchial epithelial cells via MSK1-CREB pathway. | American journal of physiology. Lung cellular and molecular physiology 20090501 |
9-Fluorenylmethoxycarbonyl-labeled peptides as substrates in a capillary electrophoresis-based assay for sirtuin enzymes. | Analytical biochemistry 20090415 |
A role for Rho-kinase in Ca-independent contractions induced by phorbol-12,13-dibutyrate. | Clinical and experimental pharmacology & physiology 20090301 |
Cyclic AMP-dependent protein kinase A and protein kinase C phosphorylate alpha4beta2 nicotinic receptor subunits at distinct stages of receptor formation and maturation. | Neuroscience 20090218 |
Differential roles of MAPKs and MSK1 signalling pathways in the regulation of c-Jun during phenylephrine-induced cardiac myocyte hypertrophy. | Molecular and cellular biochemistry 20090201 |
Obligatory role for phosphatidylinositol 4,5-bisphosphate in activation of native TRPC1 store-operated channels in vascular myocytes. | The Journal of physiology 20090201 |
Involvement of PKC in TPA-potentiated apoptosis induction during hemin-mediated erythroid differentiation in K562 cells. | Naunyn-Schmiedeberg's archives of pharmacology 20090101 |
Effect of protein kinase C and protein kinase A inhibitors on contraction of isolated femoral arteries of SHR and Wistar rats. | Physiological research 20090101 |
Nitric oxide protects the heart from ischemia-induced apoptosis and mitochondrial damage via protein kinase G mediated blockage of permeability transition and cytochrome c release. | Journal of biomedical science 20090101 |
Characterization and regulation of basal calcium influx in human peripheral blood lymphocytes. | General physiology and biophysics 20081201 |
Importance of autophosphorylation at Ser186 in the A-loop of salt inducible kinase 1 for its sustained kinase activity. | Journal of cellular biochemistry 20080801 |
Effect of aldosterone on kinetics of intracellular sodium in cortical portion of collecting ducts in rat kidney. | Bulletin of experimental biology and medicine 20080801 |
Protein kinase C is a common component of CGRP receptor desensitization induced by distinct agonists. | European journal of pharmacology 20080610 |
Differential effects of tumor necrosis factor-alpha and interleukin-1beta on cell death in human articular chondrocytes. | Osteoarthritis and cartilage 20080601 |
Heme oxygenase-1 mediates the anti-inflammatory effect of Curcumin within LPS-stimulated human monocytes. | Journal of cellular physiology 20080601 |
PKC promotes proliferation of airway smooth muscle cells by regulating cyclinD1 expression in asthmatic rats. | Acta pharmacologica Sinica 20080601 |
HTS assays using a disease-relevant cell model for interrogating the MAP kinase pathway initiated by multiple receptors. | Assay and drug development technologies 20080601 |
Host perception and signal transduction studies in wild-type Blumeria graminis f. sp. hordei and a quinoxyfen-resistant mutant implicate quinoxyfen in the inhibition of serine esterase activity. | Pest management science 20080501 |
Protein kinase C inhibitors alter neurotensin receptor binding and function in prostate cancer PC3 cells. | Regulatory peptides 20080410 |
Acrolein induces heme oxygenase-1 through PKC-delta and PI3K in human bronchial epithelial cells. | American journal of respiratory cell and molecular biology 20080401 |
Rho kinase is involved in Ca2+ entry of rat penile small arteries. | American journal of physiology. Heart and circulatory physiology 20080401 |
Multiple mechanisms are involved in 6-gingerol-induced cell growth arrest and apoptosis in human colorectal cancer cells. | Molecular carcinogenesis 20080301 |
Progress in allergy signal research on mast cells: up-regulation of histamine signal-related gene expression in allergy model rats. | Journal of pharmacological sciences 20080301 |
[Effect of lysophosphatidic acid increase the permeability of blood-brain barrier model]. | Zhonghua yi xue za zhi 20080205 |
Exposure of normal human melanocytes to a tumor promoting phorbol ester reverses growth suppression by transforming growth factor beta. | Journal of cellular physiology 20080201 |
Role of intracellular kinases in the regulation of equine eosinophil migration and actin polymerization. | Journal of veterinary pharmacology and therapeutics 20080201 |
Protein kinase C synergistically stimulates tumor necrosis factor-alpha-induced secretion of urokinase-type plasminogen activator in human dental pulp cells. | The journal of physiological sciences : JPS 20080201 |
The selectivity of protein kinase inhibitors: a further update. | The Biochemical journal 20071215 |
Effect of cigarette smoke extract on proliferation of rat pulmonary artery smooth muscle cells and the relevant roles of protein kinase C. | Chinese medical journal 20070905 |
Modulation of CCK-8-evoked intracellular Ca2+ waves by hydrogen peroxide in mouse pancreatic acinar cells. | Journal of physiology and pharmacology : an official journal of the Polish Physiological Society 20070901 |
Mechanism of membrane redistribution of protein kinase C by its ATP-competitive inhibitors. | The Biochemical journal 20070715 |
Sensitisation of TRPV1 in rat sensory neurones by activation of SNSRs. | Neuroscience letters 20070705 |
Regulation of the Na+/Ca2+ exchanger (NCX) in the murine embryonic heart. | Cardiovascular research 20070701 |
Inhibition of protein kinase C protects against paraoxon-mediated neuronal cell death. | Neurotoxicology 20070701 |
Heterologous up-regulation of the histamine H1 receptor by M3 muscarinic receptor-mediated activation of H1-receptor gene transcription. | The Journal of pharmacy and pharmacology 20070601 |
Activation of protein kinase Czeta mediates luteinizing hormone- or forskolin-induced NGFI-B expression in preovulatory granulosa cells of rat ovary. | Molecular and cellular endocrinology 20070530 |
Stimulation of histamine H1 receptor up-regulates histamine H1 receptor itself through activation of receptor gene transcription. | Journal of pharmacological sciences 20070401 |
A genomic screen for activators of the antioxidant response element. | Proceedings of the National Academy of Sciences of the United States of America 20070320 |
Effects of arsenic trioxide on the cellular proliferation, apoptosis and differentiation of human neuroblastoma cells. | Cancer letters 20070208 |
Protein kinase D2 mediates lysophosphatidic acid-induced interleukin 8 production in nontransformed human colonic epithelial cells through NF-kappaB. | American journal of physiology. Cell physiology 20070201 |
Protein kinase C activity is required for cytotoxic T cell lytic granule exocytosis, but the theta isoform does not play a preferential role. | Journal of leukocyte biology 20070201 |
Regulation of SR-BI-mediated selective lipid uptake in Chinese hamster ovary-derived cells by protein kinase signaling pathways. | Journal of lipid research 20070201 |
(+/-)3,4-Methylenedioxyamphetamine elicits action potential bursts in a central snail neuron. | Experimental neurology 20070201 |
Evidence that tumor necrosis factor-related apoptosis-inducing ligand induction by 5-Aza-2'-deoxycytidine sensitizes human breast cancer cells to adriamycin. | Cancer research 20070201 |
The inhibition of endocytosis affects HDL-lipid uptake mediated by the human scavenger receptor class B type I. | Molecular membrane biology 20070101 |
Adenosine mimetics as inhibitors of NAD+-dependent histone deacetylases, from kinase to sirtuin inhibition. | Journal of medicinal chemistry 20061214 |
Involvement of phosphatidylinositol-phospholipase C in immune response to Salmonella lipopolysacharide in chicken macrophage cells (HD11). | International immunopharmacology 20061205 |
Curcumin inhibits neurotensin-mediated interleukin-8 production and migration of HCT116 human colon cancer cells. | Clinical cancer research : an official journal of the American Association for Cancer Research 20060915 |
Inhibitors of the PI3-kinase/Akt pathway induce mitotic catastrophe in non-small cell lung cancer cells. | International journal of cancer 20060901 |
Homology model of RSK2 N-terminal kinase domain, structure-based identification of novel RSK2 inhibitors, and preliminary common pharmacophore. | Bioorganic & medicinal chemistry 20060901 |
Inhibition of protein kinase C epsilon causes ciliated bovine bronchial cell detachment. | Experimental lung research 20060901 |
Pharmacological- and gene therapy-based inhibition of protein kinase Calpha/beta enhances cardiac contractility and attenuates heart failure. | Circulation 20060808 |
P2Y12 receptor signalling towards PKB proceeds through IGF-I receptor cross-talk and requires activation of Src, Pyk2 and Rap1. | Cellular signalling 20060801 |
Acquisition of apoptotic resistance in cadmium-induced malignant transformation: specific perturbation of JNK signal transduction pathway and associated metallothionein overexpression. | Molecular carcinogenesis 20060801 |
Roles of protein kinase C, Ca2+, Pyk2, and c-Src in agonist activation of rat lacrimal gland p42/p44 MAPK. | Investigative ophthalmology & visual science 20060801 |
Zinc is required for Fc epsilon RI-mediated mast cell activation. | Journal of immunology (Baltimore, Md. : 1950) 20060715 |
Enhancement of tumor invasion depends on transdifferentiation of skin fibroblasts mediated by reactive oxygen species. | Journal of cell science 20060701 |
Actin polymerisation regulates thrombin-evoked Ca(2+) signalling after activation of PAR-4 but not PAR-1 in human platelets. | Platelets 20060501 |
Substance P initiates NFAT-dependent gene expression in spinal neurons. | Journal of neurochemistry 20060401 |
Nonclassical action of retinoic acid on the activation of the cAMP response element-binding protein in normal human bronchial epithelial cells. | Molecular biology of the cell 20060201 |
Signalling pathways evoked by alpha1-adrenoceptors in human melanoma cells. | Cell biochemistry and function 20060101 |
Albumin stimulation of eosinophil migration involves PI3-kinases and is associated with diminished eosinophil CD49d and CD49f expression. | International archives of allergy and immunology 20060101 |
Different roles of protein kinase C-betaI and -delta in the regulation of adipocyte differentiation. | The international journal of biochemistry & cell biology 20060101 |
Structural basis of inhibitor specificity of the human protooncogene proviral insertion site in moloney murine leukemia virus (PIM-1) kinase. | Journal of medicinal chemistry 20051201 |
Rho kinase inhibitors reduce neurally evoked contraction of the rat tail artery in vitro. | British journal of pharmacology 20051101 |
Intraplatelet signaling mechanisms of the priming effect of matrix metalloproteinase-2 on platelet aggregation. | Journal of thrombosis and haemostasis : JTH 20051101 |
Native and oxidized low-density lipoproteins stimulate endothelin-converting enzyme-1 expression in human endothelial cells. | Biochemical and biophysical research communications 20050902 |
Interleukin-10 inhibits lipopolysaccharide-induced survival and extracellular signal-regulated kinase activation in human neutrophils. | European journal of immunology 20050901 |
Overexpression of heat-shock protein 20 in rat heart myogenic cells confers protection against simulated ischemia/reperfusion injury. | Acta pharmacologica Sinica 20050901 |
Acute IL-3 priming up-regulates the stimulus-induced Raf-1-Mek-Erk cascade independently of IL-3-induced activation of Erk. | Journal of immunology (Baltimore, Md. : 1950) 20050901 |
Glycogen synthase kinase 3-dependent phosphorylation of Mdm2 regulates p53 abundance. | Molecular and cellular biology 20050801 |
Inhibition of CREB transcriptional activity in human T lymphocytes by oxidative stress. | Free radical biology & medicine 20050615 |
Vitamin C inhibits platelet expression of CD40 ligand. | Free radical biology & medicine 20050615 |
Effects of bisindolylmaleimide PKC inhibitors on p90RSK activity in vitro and in adult ventricular myocytes. | British journal of pharmacology 20050601 |
The cytosolic phospholipase A2 pathway, a safeguard of beta2-adrenergic cardiac effects in rat. | The Journal of biological chemistry 20050513 |
Group I metabotropic glutamate receptors, mGlu1a and mGlu5a, couple to cyclic AMP response element binding protein (CREB) through a common Ca2+ - and protein kinase C-dependent pathway. | Journal of neurochemistry 20050401 |
Effect of GLP-1 on glucose transport and its cell signalling in human myocytes. | Regulatory peptides 20050330 |
The role of protein kinase C in regulating equine eosinophil adherence and superoxide production. | Inflammation research : official journal of the European Histamine Research Society ... [et al.] 20050301 |
Mechanisms of desensitization of the adrenocorticotropin response to arginine vasopressin in ovine anterior pituitary cells. | The Journal of endocrinology 20050101 |
The synthetic chemoattractant peptide WKYMVm induces superoxide production by human eosinophils via the phosphoinositide 3-kinase-mediated activation of ERK1/2. | International archives of allergy and immunology 20050101 |
[Effects of guanine nucleotides and protein kinase C on prolactin-stimulated release of Ca from intracellular stores of pig oocytes]. | Ontogenez 20050101 |
Massive augmentation of stimulated insulin secretion induced by fatty acid-free BSA in rat pancreatic islets. | Diabetes 20041201 |
Transcriptional up-regulation in expression of 5-hydroxytryptamine2A and transcriptional down-regulation of angiotensin II type 1 receptors during organ culture of rat mesenteric artery. | Basic & clinical pharmacology & toxicology 20041201 |
A novel Ca2+-independent signaling pathway to extracellular signal-regulated protein kinase by coactivation of NMDA receptors and metabotropic glutamate receptor 5 in neurons. | The Journal of neuroscience : the official journal of the Society for Neuroscience 20041201 |
Specificity of action of bisindolylmaleimide protein kinase C inhibitors: do they inhibit the 70kDa ribosomal S6 kinase in cardiac myocytes? | Biochemical pharmacology 20041115 |
IL-10 production induced by HIV-1 Tat stimulation of human monocytes is dependent on the activation of PKC beta(II) and delta isozymes. | Microbes and infection 20041101 |
Mechanisms of mitogen-activated protein kinase inhibition by parathyroid hormone in osteoblast-like cells. | Journal of the American Society of Nephrology : JASN 20041101 |
Phenylephrine induces activation of CREB in adult rat cardiac myocytes through MSK1 and PKA signaling pathways. | Journal of molecular and cellular cardiology 20041101 |
Regulation of beta1 integrin expression by PKCepsilon in renal cancer cells. | International journal of oncology 20041001 |
Inhibition of human immunodeficiency virus type 1 replication by Z-100, an immunomodulator extracted from human-type tubercle bacilli, in macrophages. | The Journal of general virology 20040901 |
Protein kinase Calpha translocates to the perinuclear region to activate phospholipase D1. | The Journal of biological chemistry 20040820 |
Identifying pathways involved in leptin-dependent aggregation of human platelets. | International journal of obesity and related metabolic disorders : journal of the International Association for the Study of Obesity 20040801 |
Inhibition of MKP-1 expression potentiates JNK related apoptosis in renal cancer cells. | The Journal of urology 20040801 |
Histamine H1 receptor down-regulation mediated by M3 muscarinic acetylcholine receptor subtype. | Journal of pharmacological sciences 20040801 |
ATP priming of macrophage-derived chemokine responses in CHO cells expressing the CCR4 receptor. | Naunyn-Schmiedeberg's archives of pharmacology 20040701 |
Interleukin-1beta stimulates matrix metalloproteinase-2 expression via a prostaglandin E2-dependent mechanism in human chondrocytes. | Experimental & molecular medicine 20040630 |
Potent activation of multiple signalling pathways by C-peptide in opossum kidney proximal tubular cells. | Diabetologia 20040601 |
Regulation of phospholipase D2 activity by protein kinase C alpha. | The Journal of biological chemistry 20040521 |
Inhibitors of protein kinase C (PKC) prevent activated transcription: role of events downstream of NF-kappaB DNA binding. | The Journal of biological chemistry 20040430 |
gp91phox-containing NADPH oxidase mediates endothelial dysfunction in renovascular hypertension. | Circulation 20040413 |
Mechanisms of action of melanin-concentrating hormone in the teleost fish erythrophoroma cell line (GEM-81). | General and comparative endocrinology 20040401 |
The role of calcium, calcium-activated K+ channels, and tyrosine/kinase in psoralen-evoked responses in human melanoma cells. | Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas 20040401 |
Cell signalling of glucagon-like peptide-1 action in rat skeletal muscle. | The Journal of endocrinology 20040301 |
Phosphatidylinositol 3-kinase activation is required for sulfonylurea stimulation of glucose transport in rat skeletal muscle. | Endocrinology 20040201 |
Stimulation of CD36 and the key effector of reverse cholesterol transport ATP-binding cassette A1 in monocytoid cells by niacin. | Biochemical pharmacology 20040201 |
Modulation of histamine-induced Ca2+ release by protein kinase C. Effects on cytosolic and mitochondrial [Ca2+] peaks. | The Journal of biological chemistry 20031212 |
Phorbol esters and adenosine affect the readily releasable neurotransmitter pool by different mechanisms at amphibian motor nerve endings. | The Journal of physiology 20031201 |
Differential implication of protein kinase C isoforms in cytotoxic T lymphocyte degranulation and TCR-induced Fas ligand expression. | International immunology 20031201 |
The role of rho and rho-dependent kinase in serotonin-induced contraction observed in bovine middle cerebral artery. | The Tohoku journal of experimental medicine 20031201 |
Protein kinase C (PKC) isotype profile in eosinophils from ponies with sweet itch and role in histamine-induced eosinophil activation. | Veterinary immunology and immunopathology 20031115 |
Regulated cell surface pro-EGF ectodomain shedding is a zinc metalloprotease-dependent process. | The Journal of biological chemistry 20031114 |
Rapid agonist-evoked coupling of type II Ins(1,4,5)P3 receptor with human transient receptor potential (hTRPC1) channels in human platelets. | The Biochemical journal 20031101 |
Mitogenic effects of phospholipase D and phosphatidic acid in transiently permeabilized astrocytes: effects of ethanol. | Journal of neurochemistry 20031001 |
Arsenite stimulated glucose transport in 3T3-L1 adipocytes involves both Glut4 translocation and p38 MAPK activity. | European journal of biochemistry 20031001 |
Amlodipine activates the endothelial nitric oxide synthase by altering phosphorylation on Ser1177 and Thr495. | Cardiovascular research 20031001 |
Homocysteine mediated expression and secretion of monocyte chemoattractant protein-1 and interleukin-8 in human monocytes. | Circulation research 20030822 |
C-terminal fragment of tetanus toxin heavy chain activates Akt and MEK/ERK signalling pathways in a Trk receptor-dependent manner in cultured cortical neurons. | The Biochemical journal 20030715 |
Inhibition of protein kinase CbetaII increases glucose uptake in 3T3-L1 adipocytes through elevated expression of glucose transporter 1 at the plasma membrane. | Molecular endocrinology (Baltimore, Md.) 20030701 |
Variations in cell signaling pathways for different vasoconstrictor agonists in renal circulation of the rat. | Kidney international 20030601 |
Unique T cell proliferation associated with PKCmu activation and impaired ZAP-70 phosphorylation in recognition of overexpressed HLA/partially agonistic peptide complexes. | European journal of immunology 20030601 |
Inhibition of histamine H1 receptor downregulation by KT5823, a protein kinase G inhibitor. | Methods and findings in experimental and clinical pharmacology 20030601 |
Phosphorylation of the alpha4 subunit of human alpha4beta2 nicotinic receptors: role of cAMP-dependent protein kinase (PKA) and protein kinase C (PKC). | Brain research. Molecular brain research 20030526 |
Distinct protein kinase C isoforms mediate regulation of vascular endothelial growth factor expression by A2A adenosine receptor activation and phorbol esters in pheochromocytoma PC12 cells. | The Journal of biological chemistry 20030425 |
[Effect of protein kinase C on K(V) channel in rat bronchial smooth muscle]. | Sheng li xue bao : [Acta physiologica Sinica] 20030425 |
Activation of protein kinase C inhibits retrograde transport of neurotrophins in mice. | Journal of neuroscience research 20030415 |
Kinase inhibitors: not just for kinases anymore. | Journal of medicinal chemistry 20030410 |
Effect of the lipid peroxidation product acrolein on tau phosphorylation in neural cells. | Journal of neuroscience research 20030315 |
Lithium inhibits a late step in agrin-induced AChR aggregation. | Journal of neurobiology 20030205 |
Essential role of rho kinase in the Ca2+ sensitization of prostaglandin F(2alpha)-induced contraction of rabbit aortae. | The Journal of physiology 20030201 |
Thrombin rapidly induces protein kinase D phosphorylation, and protein kinase C delta mediates the activation. | The Journal of biological chemistry 20030131 |
Activation of RAF-1 through Ras and protein kinase Calpha mediates 1alpha,25(OH)2-vitamin D3 regulation of the mitogen-activated protein kinase pathway in muscle cells. | The Journal of biological chemistry 20030124 |
Negative regulation of phosphatidylinositol 3-kinase and Akt signalling pathway by PKC. | Cellular signalling 20030101 |
Rho-kinase inhibition blunts renal vasoconstriction induced by distinct signaling pathways in vivo. | Journal of the American Society of Nephrology : JASN 20030101 |
The involvement of lipid activators of protein kinase C in the induction of ZIF268 in PC12 cells exposed to lead. | Neurochemical research 20030101 |
Endothelial NADPH oxidase: mechanism of activation by low-density lipoprotein. | Endothelium : journal of endothelial cell research 20030101 |
Ca2+-stimulated Ca2+ oscillations produced by the Ca2+-sensing receptor require negative feedback by protein kinase C. | The Journal of biological chemistry 20021206 |
Protein kinase C- and calcium-regulated pathways independently synergize with Gi pathways in agonist-induced fibrinogen receptor activation. | The Biochemical journal 20021201 |
alpha1B-Adrenergic receptor phosphorylation and desensitization induced by transforming growth factor-beta. | The Biochemical journal 20021201 |
Immediate and delayed VEGF-mediated NO synthesis in endothelial cells: role of PI3K, PKC and PLC pathways. | British journal of pharmacology 20021201 |
Interleukin-1beta induces MUC2 gene expression and mucin secretion via activation of PKC-MEK/ERK, and PI3K in human airway epithelial cells. | Journal of Korean medical science 20021201 |
Up-regulation of c-jun mRNA in cardiac myocytes requires the extracellular signal-regulated kinase cascade, but c-Jun N-terminal kinases are required for efficient up-regulation of c-Jun protein. | The Biochemical journal 20021115 |
Regulation of follistatin-related gene (FLRG) expression by protein kinase C and prostaglandin E(2) in cultured granulosa-luteal cells. | Molecular human reproduction 20021101 |
PGD(2) modulates fibroblast-mediated native collagen gel contraction. | American journal of respiratory cell and molecular biology 20020901 |
Failure to activate caspase 3 in phorbol ester-resistant leukemia cells is associated with resistance to apoptotic cell death. | Cancer letters 20020828 |
The role of calcium in oligogalacturonide-activated signalling in soybean cells. | Planta 20020801 |
Superoxide anion-dependent Raf/MEK/ERK activation by peroxisome proliferator activated receptor gamma agonists 15-deoxy-delta(12,14)-prostaglandin J(2), ciglitazone, and GW1929. | Experimental cell research 20020715 |
Impaired protein kinase C activation/translocation in Epstein-Barr virus-infected monocytes. | The Journal of biological chemistry 20020705 |
Different actions of protein kinase C isoforms alpha and epsilon on gastric acid secretion. | British journal of pharmacology 20020701 |
Exendin-4 as a stimulator of rat insulin I gene promoter activity via bZIP/CRE interactions sensitive to serine/threonine protein kinase inhibitor Ro 31-8220. | Endocrinology 20020601 |
Ro 31-6045, the inactive analogue of the protein kinase C inhibitor Ro 31-8220, blocks in vivo activation of p70(s6k)/p85(s6k): implications for the analysis of S6K signalling. | FEBS letters 20020522 |
Involvement of protein kinase D in Fc gamma-receptor activation of the NADPH oxidase in neutrophils. | The Biochemical journal 20020401 |
Inhibition of rho-kinase-induced myristoylated alanine-rich C kinase substrate (MARCKS) phosphorylation in human neuronal cells by H-1152, a novel and specific Rho-kinase inhibitor. | Journal of neurochemistry 20020401 |
Phorbol esters inhibit fibroblast growth factor-2-stimulated fibroblast proliferation by a p38 MAP kinase dependent pathway. | Oncogene 20020327 |
Phosphorylation-dependent regulation of phospholipase D2 by protein kinase C delta in rat Pheochromocytoma PC12 cells. | The Journal of biological chemistry 20020308 |
Regulation of cyclooxygenase-2 expression by phospholipase D in human amnion-derived WISH cells. | Molecular pharmacology 20020301 |
Protein kinase D is a downstream target of protein kinase Ctheta. | Biochemical and biophysical research communications 20020301 |
Protein phosphatase 2A and protein kinase Calpha are physically associated and are involved in Pseudomonas aeruginosa-induced interleukin 6 production by mast cells. | The Journal of biological chemistry 20020215 |
Over-expression of the glucagon-like peptide-1 receptor on INS-1 cells confers autocrine stimulation of insulin gene promoter activity: a strategy for production of pancreatic beta-cell lines for use in transplantation. | Cell and tissue research 20020201 |
The cytoplasmic tail of L-selectin interacts with members of the Ezrin-Radixin-Moesin (ERM) family of proteins: cell activation-dependent binding of Moesin but not Ezrin. | The Journal of biological chemistry 20020118 |
Protein kinase C epsilon mediates the induction of P-glycoprotein in LNCaP prostate carcinoma cells. | Cellular signalling 20020101 |
Acquisition of apoptotic resistance in arsenic-induced malignant transformation: role of the JNK signal transduction pathway. | Carcinogenesis 20020101 |
Selective induction of mitogen-activated protein kinases in human lens epithelial cells by ultraviolet radiation. | Journal of biochemical and molecular toxicology 20020101 |
[Involvement of protein kinase C in the regulation of Ca2+ exit from intracellular stores of prolactin stimulated pig oocytes]. | Tsitologiia 20020101 |
Multiple signaling pathways involved in activation of matrix metalloproteinase-9 (MMP-9) by heregulin-beta1 in human breast cancer cells. | Oncogene 20011206 |
Regulation of SP-B and SP-C secretion in rat type II cells in primary culture. | American journal of physiology. Lung cellular and molecular physiology 20011201 |
Synergistic effect of urotensin II with serotonin on vascular smooth muscle cell proliferation. | Journal of hypertension 20011201 |
Signalling components underlying platelet aggregation to a Ca2+ ionophore and a phorbol ester. | Platelets 20011201 |
Phosphorylation is involved in the activation of metal-regulatory transcription factor 1 in response to metal ions. | The Journal of biological chemistry 20011109 |
Characterisation of Rac activation in thrombin- and collagen-stimulated human blood platelets. | FEBS letters 20011102 |
Nuclear factor-kappa B augments beta(2)-adrenergic receptor expression in human airway epithelial cells. | American journal of physiology. Lung cellular and molecular physiology 20011101 |
Transcription activator protein 1 (AP-1) mediates NO-induced apoptosis of adult cardiomyocytes. | FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20011101 |
PKC- and ERK-dependent activation of I kappa B kinase by lipopolysaccharide in macrophages: enhancement by P2Y receptor-mediated CaMK activation. | British journal of pharmacology 20011101 |
Effects of homocysteine on murine splenic B lymphocyte proliferation and its signal transduction mechanism. | Cardiovascular research 20011101 |
Activation of protein kinase D by signaling through Rho and the alpha subunit of the heterotrimeric G protein G13. | The Journal of biological chemistry 20011019 |
Regulation of phospholipase D isoenzymes by transforming Ras and atypical protein kinase C-iota. | The Biochemical journal 20011001 |
Signalling events underlying platelet aggregation induced by the glycoprotein VI agonist convulxin. | European journal of biochemistry 20011001 |
Pharmacological comparison of LTB(4)-induced NADPH oxidase activation in adherent and non-adherent guinea-pig eosinophils. | British journal of pharmacology 20011001 |
[A study of the effect of protein kinase C on the expression of nitric oxide synthase mRNA in pulmonary artery smooth muscle in hypoxia]. | Zhonghua jie he he hu xi za zhi = Zhonghua jiehe he huxi zazhi = Chinese journal of tuberculosis and respiratory diseases 20011001 |
Gene expression profile in BALB/c-3T3 cells transformed with beryllium sulfate. | Molecular carcinogenesis 20010901 |
Inotropic actions of protein kinase C activation by phorbol dibutyrate in guinea-pig isolated ventricular myocytes. | Experimental physiology 20010901 |
Differences in functional consequences and signal transduction induced by IL-3, IL-5, and nerve growth factor in human basophils. | Journal of immunology (Baltimore, Md. : 1950) 20010815 |
Histamine-induced vasoconstriction involves phosphorylation of a specific inhibitor protein for myosin phosphatase by protein kinase C alpha and delta isoforms. | The Journal of biological chemistry 20010803 |
beta-estradiol stimulation of DNA synthesis requires different PKC isoforms in HepG2 and MCF7 cells. | Journal of cellular physiology 20010801 |
Oxidized low-density lipoprotein downregulates endothelial basic fibroblast growth factor through a pertussis toxin-sensitive G-protein pathway: mediator role of platelet-activating factor-like phospholipids. | Circulation 20010731 |
Actions of arachidonic acid on contractions and associated electrical activity in guinea-pig isolated ventricular myocytes. | Experimental physiology 20010701 |
Hyaluronan fragments induce the synthesis of MCP-1 and IL-8 in cultured human peritoneal mesothelial cells. | Cell and tissue research 20010701 |
Sustained norepinephrine stimulation induces different regulation of expression in three alpha1-adrenoceptor subtypes. | Life sciences 20010608 |
Cadmium-induced cell transformation and tumorigenesis are associated with transcriptional activation of c-fos, c-jun, and c-myc proto-oncogenes: role of cellular calcium and reactive oxygen species. | Toxicological sciences : an official journal of the Society of Toxicology 20010601 |
Oxytocin stimulates prostaglandin F2alpha secretion from porcine endometrial cells through activation of calcium-dependent protein kinase C. | Prostaglandins & other lipid mediators 20010601 |
Effect of protein kinase C activation on the glycine evoked Cl(-) current in spinal cord neurons. | Brain research 20010525 |
Extracellular ATP stimulates an inhibitory pathway towards growth factor-induced cRaf-1 and MEKK activation in astrocyte cultures. | Journal of neurochemistry 20010501 |
Hypoxic enhancement of evoked noradrenaline release from the human neuroblastoma SH-SY5Y. | Brain research. Molecular brain research 20010418 |
Hypoxia induces the release of a pulmonary-selective, Ca(2+)-sensitising, vasoconstrictor from the perfused rat lung. | Cardiovascular research 20010401 |
Signalling pathways regulating the dephosphorylation of Ser729 in the hydrophobic domain of protein kinase Cepsilon upon cell passage. | The Journal of biological chemistry 20010330 |
Lipid peroxidation product 4-hydroxy-2-nonenal acts synergistically with serotonin in inducing vascular smooth muscle cell proliferation. | Atherosclerosis 20010301 |
Modulation of the neuronal dopamine transporter activity by the metabotropic glutamate receptor mGluR5 in rat striatal synaptosomes through phosphorylation mediated processes. | Journal of neurochemistry 20010301 |
Signaling mechanism underlying COX-2 induction by lysophosphatidylcholine. | Biochemical and biophysical research communications 20010301 |
Integrin-independent tyrosine phosphorylation of p125(fak) in human platelets stimulated by collagen. | The Journal of biological chemistry 20010202 |
Vascular endothelial growth factor enhances the expression of urokinase receptor in human endothelial cells via protein kinase C activation. | Thrombosis and haemostasis 20010201 |
p53-independent elevation of p21 expression by PMA results from PKC-mediated mRNA stabilization. | Biochemical and biophysical research communications 20010112 |
Selective secretion of protein kinase C isozymes by thrombin-stimulated human platelets. | Biochemical and biophysical research communications 20010112 |
Ceramide binds to the CaLB domain of cytosolic phospholipase A2 and facilitates its membrane docking and arachidonic acid release. | FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20010101 |
Bradykinin induces protein kinase C-dependent activation of phospholipase D in A-431 cells. | IUBMB life 20010101 |
Monocyte chemotactic protein 1 amplifies serotonin-induced vascular smooth muscle cell proliferation. | Journal of vascular research 20010101 |
[Effect of elastin peptides on the production of matrix metalloproteinase 2 by human skin fibroblasts in culture]. | Journal de la Societe de biologie 20010101 |
Specificity and mechanism of action of some commonly used protein kinase inhibitors. | The Biochemical journal 20001001 |
ERK signaling mediates the induction of inflammatory cytokines by bufalin in human monocytic cells. | American journal of physiology. Cell physiology 20000301 |
Protein phosphatase-protein kinase interplay modulates alpha 1b-adrenoceptor phosphorylation: effects of okadaic acid. | British journal of pharmacology 20000201 |
Studies on the mechanism of fibrate-inhibited expression of plasminogen activator inhibitor-1 in cultured hepatocytes from cynomolgus monkey. | Arteriosclerosis, thrombosis, and vascular biology 19970101 |
Differential inhibition of cytosolic and membrane-derived protein kinase C activity by staurosporine and other kinase inhibitors. | FEBS letters 19950403 |
Isoenzyme specificity of bisindolylmaleimides, selective inhibitors of protein kinase C. | The Biochemical journal 19930901 |
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