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124832-26-4 | L-Valine, 2-[(2-amino-1,6-dihydro-6-oxo-9H-purin-9-yl)methoxy]ethyl ester
CAS No: 124832-26-4 Catalog No: AG000MSD MDL No:MFCD00866955
Product Description
Catalog Number:
AG000MSD
Chemical Name:
L-Valine, 2-[(2-amino-1,6-dihydro-6-oxo-9H-purin-9-yl)methoxy]ethyl ester
CAS Number:
124832-26-4
Molecular Formula:
C13H20N6O4
Molecular Weight:
324.3357
MDL Number:
MFCD00866955
IUPAC Name:
2-[(2-amino-6-oxo-1H-purin-9-yl)methoxy]ethyl (2S)-2-amino-3-methylbutanoate
InChI:
InChI=1S/C13H20N6O4/c1-7(2)8(14)12(21)23-4-3-22-6-19-5-16-9-10(19)17-13(15)18-11(9)20/h5,7-8H,3-4,6,14H2,1-2H3,(H3,15,17,18,20)/t8-/m0/s1
InChI Key:
HDOVUKNUBWVHOX-QMMMGPOBSA-N
SMILES:
CC([C@@H](C(=O)OCCOCn1cnc2c1nc(N)[nH]c2=O)N)C
EC Number:
603-015-6
UNII:
MZ1IW7Q79D
Properties
Complexity:
483
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
1
Defined Atom Stereocenter Count:
1
Defined Bond Stereocenter Count:
0
Exact Mass:
324.155g/mol
Formal Charge:
0
Heavy Atom Count:
23
Hydrogen Bond Acceptor Count:
7
Hydrogen Bond Donor Count:
3
Isotope Atom Count:
0
Molecular Weight:
324.341g/mol
Monoisotopic Mass:
324.155g/mol
Rotatable Bond Count:
8
Topological Polar Surface Area:
147A^2
Undefined Atom Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
XLogP3:
-0.9
Literature
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| Valacyclovir prophylaxis versus preemptive valganciclovir therapy to prevent cytomegalovirus disease after renal transplantation. | American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20080101 |
| Allergic drug eruption secondary to intravenous acyclovir. | Acta dermato-venereologica 20080101 |
| Ring corneal infiltrate and progressive ring thinning following primary varicella infection. | Journal of pediatric ophthalmology and strabismus 20080101 |
| Medical management approach to infectious keratitis. | Indian journal of ophthalmology 20080101 |
| Erythema annulare centrifugum associated with herpes zoster. | European journal of dermatology : EJD 20080101 |
| Genital herpes has played a more important role than any other sexually transmitted infection in driving HIV prevalence in Africa. | PloS one 20080101 |
| [Cytomegalovirus infection in renal transplant recipients]. | Acta medica Croatica : casopis Hravatske akademije medicinskih znanosti 20080101 |
| Effects of anti herpetic drugs on mice with herpetic epithelial keratitis after reactivation of herpes simplex virus type 1. | Seminars in ophthalmology 20080101 |
| Therapy for acute retinal necrosis. | Seminars in ophthalmology 20080101 |
| [Human infection with simian herpes B virus in Africa]. | Sante (Montrouge, France) 20080101 |
| Antiviral Chemistry & Chemotherapy's current antiviral agents FactFile (2nd edition): DNA viruses. | Antiviral chemistry & chemotherapy 20080101 |
| Progressive hypertrophic genital herpes in an HIV-infected woman despite immune recovery on antiretroviral therapy. | Infectious diseases in obstetrics and gynecology 20080101 |
| Influence of ALDH2 genetic polymorphisms on aciclovir pharmacokinetics following oral administration of valaciclovir in Japanese end-stage renal disease patients. | Drug metabolism and pharmacokinetics 20080101 |
| Ability of online drug databases to assist in clinical decision-making with infectious disease therapies. | BMC infectious diseases 20080101 |
| Drug-resistant herpes simplex virus in HIV infected patients. | Acta dermatovenerologica Croatica : ADC 20080101 |
| Radiofrequency in dermatosurgery. | Journal of cutaneous and aesthetic surgery 20080101 |
| Death delusion. | BMJ (Clinical research ed.) 20071222 |
| Rise in seroprevalence of herpes simplex virus type 1 among highly sexual active homosexual men and an increasing association between herpes simplex virus type 2 and HIV over time (1984-2003). | European journal of epidemiology 20071201 |
| Long-term outcome of phase I/II clinical trial of Ad-OC-TK/VAL gene therapy for hormone-refractory metastatic prostate cancer. | Human gene therapy 20071201 |
| Oral drugs for viral retinitis. | Ophthalmology 20071201 |
| Efficacy and safety of universal valganciclovir prophylaxis combined with a tacrolimus/mycophenolate-based regimen in kidney transplantation. | Swiss medical weekly 20071201 |
| [Valaciclovir]. | Revue de l'infirmiere 20071201 |
| Rhodococcus equi infection after alemtuzumab therapy for T-cell prolymphocytic leukemia. | Emerging infectious diseases 20071201 |
| Management and prevention of recurrent herpes labialis in immunocompetent patients. | Herpes : the journal of the IHMF 20071201 |
| Herpes simplex virus (HSV) suppression with valacyclovir reduces rectal and blood plasma HIV-1 levels in HIV-1/HSV-2-seropositive men: a randomized, double-blind, placebo-controlled crossover trial. | The Journal of infectious diseases 20071115 |
| Archipelago keratitis: a clinical variant of recurrent herpetic keratitis? | Ophthalmology 20071101 |
| Surgical excision for vegetative herpes simplex virus infection. | Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.] 20071101 |
| Herpes zoster in 2007: treatment and prevention. | JAAPA : official journal of the American Academy of Physician Assistants 20071101 |
| Less common MRI findings in ramsay hunt syndrome type I. | Ear, nose, & throat journal 20071101 |
| One-year acyclovir prophylaxis for preventing varicella-zoster virus disease after hematopoietic cell transplantation: no evidence of rebound varicella-zoster virus disease after drug discontinuation. | Blood 20071015 |
| Efficacy of valacyclovir vs acyclovir for the prevention of recurrent herpes simplex virus eye disease: a pilot study. | American journal of ophthalmology 20071001 |
| Acute varicella infection mimics recurrent Hodgkin's disease on F-18 FDG PET/CT. | Clinical nuclear medicine 20071001 |
| Bell's palsy: diagnosis and management. | American family physician 20071001 |
| Maternal administration of valaciclovir in symptomatic intrauterine cytomegalovirus infection. | BJOG : an international journal of obstetrics and gynaecology 20070901 |
| Varicella zoster virus: natural history and current therapies of varicella and herpes zoster. | Herpes : the journal of the IHMF 20070901 |
| Managing herpes zoster in immunocompromised patients. | Herpes : the journal of the IHMF 20070901 |
| A meta-analysis to assess the efficacy of oral antiviral treatment to prevent genital herpes outbreaks. | Journal of the American Academy of Dermatology 20070801 |
| Prevention of shingles: safety and efficacy of live zoster vaccine. | Therapeutics and clinical risk management 20070801 |
| Screening and treatment for sexually transmitted infections in pregnancy. | American family physician 20070715 |
| The change in zoster-associated pain treated with oral valaciclovir in immunocompetent patients with acute herpes zoster. | International journal of clinical practice 20070701 |
| Regulation of the oligopeptide transporter, PEPT-1, in DSS-induced rat colitis. | Digestive diseases and sciences 20070701 |
| Clinical inquiries. What are the best treatments for herpes labialis? | The Journal of family practice 20070701 |
| Suppressive therapy with valacyclovir in early genital herpes: a pilot study of clinical efficacy and herpes-related quality of life. | Sexually transmitted diseases 20070601 |
| Herpes simplex and varicella-zoster virus infections during pregnancy: current concepts of prevention, diagnosis and therapy. Part 1: herpes simplex virus infections. | Medical microbiology and immunology 20070601 |
| Thalidomide therapy for the treatment of hypertrophic herpes simplex virus-related genitalis in HIV-infected individuals. | Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20070601 |
| Famciclovir or valaciclovir in the management of herpes simplex and varicella zoster infections: an attitudinal survey of clinician perceptions of differential activity. | Sexual health 20070601 |
| Alemtuzumab in chronic lymphocytic leukemia. | Current oncology (Toronto, Ont.) 20070601 |
| [Risk of CNS adverse effects of aciclovir and valaciclovir. Watch the renal function in treatment of herpes simplex and herpes zoster]. | Lakartidningen 20070601 |
| Review of recent HSV recurrent-infection treatment studies. | Herpes : the journal of the IHMF 20070601 |
| An update on short-course intermittent and prevention therapies for herpes labialis. | Herpes : the journal of the IHMF 20070601 |
| HSV therapy and HIV-1 reduction. | The New England journal of medicine 20070531 |
| HSV therapy and HIV-1 reduction. | The New England journal of medicine 20070531 |
| A comparison of one year of episodic or suppressive treatment of recurrent genital herpes with valacyclovir. | Sexually transmitted diseases 20070501 |
| A virologic pilot study of valacyclovir in infectious mononucleosis. | Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology 20070501 |
| By the way, doctor. My 47-year-old son suddenly lost hearing in one ear. They did some blood tests and he was given steroids and a medication called Valtrex. Now they are saying nothing can be done. Can you please address this issue? | Harvard health letter 20070401 |
| Valacyclovir and prednisolone treatment for Bell's palsy: a multicenter, randomized, placebo-controlled study. | Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology 20070401 |
| Herpes treatment may limit HIV transmission and progression. | The Lancet. Infectious diseases 20070401 |
| [Erroneous prescriptions of aciclovir and valaciclovir in herpes zoster treatment]. | Revista chilena de infectologia : organo oficial de la Sociedad Chilena de Infectologia 20070401 |
| Suppressive therapy versus episodic therapy with oral valacyclovir for recurrent herpes labialis: efficacy and tolerability in an open-label, crossover study. | Journal of drugs in dermatology : JDD 20070401 |
| Development and validation of enantioselective high performance liquid chromatographic method for Valacyclovir, an antiviral drug in drug substance. | Journal of pharmaceutical and biomedical analysis 20070312 |
| Suppressive valacyclovir therapy: impact on the population spread of HSV-2 infection. | Sexually transmitted diseases 20070301 |
| An unusual vulval lesion in an HIV-infected woman. | International journal of STD & AIDS 20070301 |
| Management of recurrent oral herpes simplex infections. | Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics 20070301 |
| Management of oral lesions in HIV-positive patients. | Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics 20070301 |
| [Streptococcal impetigo at topical tacrolimus application sites in a woman with atopic dermatitis]. | Annales de dermatologie et de venereologie 20070301 |
| Reduction of HIV-1 RNA levels with therapy to suppress herpes simplex virus. | The New England journal of medicine 20070222 |
| Treatment of acute retinal necrosis syndrome with oral antiviral medications. | Ophthalmology 20070201 |
| Acute lymphoblastic leukemia presenting as acute renal failure. | Nature clinical practice. Nephrology 20070201 |
| Single-day therapy: an expert opinion on a recent development for the episodic treatment of recurrent genital herpes. | Archives of gynecology and obstetrics 20070101 |
| Valacyclovir and pregnancy study: science or marketing. | American journal of obstetrics and gynecology 20070101 |
| Recommendations for the management of herpes zoster. | Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20070101 |
| Reactivation of herpes simplex virus type 1 and varicella-zoster virus and therapeutic effects of combination therapy with prednisolone and valacyclovir in patients with Bell's palsy. | The Laryngoscope 20070101 |
| Superior efficacy of helicase-primase inhibitor BAY 57-1293 for herpes infection and latency in the guinea pig model of human genital herpes disease. | Antiviral chemistry & chemotherapy 20070101 |
| Treatment of cytomegalovirus anterior uveitis with oral valaciclovir. | Ocular immunology and inflammation 20070101 |
| Open-label study of valacyclovir 1.5 g twice daily for the treatment of uncomplicated herpes zoster in immunocompetent patients 18 years of age or older. | Journal of cutaneous medicine and surgery 20070101 |
| Herpes simplex virus: it's more than a cold sore. | Missouri medicine 20070101 |
| Usefulness of Herpes Consensus PCR methodology to routine diagnostic testing for herpesviruses infections in clinical specimens. | Virology journal 20070101 |
| One hundred twenty recurrences of herpes simplex virus in an immunocompetent patient. | Skinmed 20070101 |
| Herpetic optic neuritis associated with herpetic keratitis. | European journal of ophthalmology 20070101 |
| Acute pancreatitis related to therapeutic dosing with colchicine: a case report. | Journal of medical case reports 20070101 |
| HIV-1/HSV-2 co-infected adults in early HIV-1 infection have elevated CD4+ T cell counts. | PloS one 20070101 |
| Valacyclovir treatment in Epstein-Barr virus subset chronic fatigue syndrome: thirty-six months follow-up. | In vivo (Athens, Greece) 20070101 |
| Optical coherence tomography of progressive outer retinal necrosis. | Retina (Philadelphia, Pa.) 20070101 |
| Long-term preservation of vision in progressive outer retinal necrosis treated with combination antiviral drugs and highly active antiretroviral therapy. | Ocular immunology and inflammation 20070101 |
| Chickenpox. | BMJ clinical evidence 20070101 |
| Primary treatment of acute retinal necrosis with oral antiviral therapy. | Ophthalmology 20061201 |
| Effect of oral valaciclovir on herpetic keratitis. | Cornea 20061201 |
| Valacyclovir prophylaxis to prevent recurrent herpes at delivery: a randomized clinical trial. | Obstetrics and gynecology 20061201 |
| Erythema multiforme. | American family physician 20061201 |
| Impact of suppressive herpes therapy on genital HIV-1 RNA among women taking antiretroviral therapy: a randomized controlled trial. | AIDS (London, England) 20061128 |
| Routine clinical use of alemtuzumab in patients with heavily pretreated B-cell chronic lymphocytic leukemia: a nation-wide retrospective study in Austria. | Cancer 20061115 |
| Recurrent benign lymphocytic meningitis. | Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20061101 |
| Prevention of VZV infection in immunosuppressed patients using antiviral agents. | Herpes : the journal of the IHMF 20061101 |
| Bell's palsy: a review of treatment using antiviral agents. | The Annals of pharmacotherapy 20061001 |
| Efficacy of oral antiviral prophylaxis in preventing ocular herpes simplex virus recurrences in patients with and without self-reported atopy. | American journal of ophthalmology 20061001 |
| Laserbrasion: the combination of carbon dioxide laser and dermasanding. | Plastic and reconstructive surgery 20061001 |
| Effect of valacyclovir on viral shedding in immunocompetent patients with recurrent herpes simplex virus 2 genital herpes: a US-based randomized, double-blind, placebo-controlled clinical trial. | Mayo Clinic proceedings 20061001 |
| Postexposure prophylaxis against varicella zoster virus infection among hematopoietic stem cell transplant recipients. | Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation 20061001 |
| Herpes labialis. | BMJ clinical evidence 20061001 |
| Acute retinal necrosis diagnosed in a child with chronic panuveitis. | Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie 20060901 |
| Comparative efficacy of famciclovir and valacyclovir for suppression of recurrent genital herpes and viral shedding. | Sexually transmitted diseases 20060901 |
| Antiviral drugs for cytomegalovirus diseases. | Antiviral research 20060901 |
| Are the antiherpes nucleosides really all the same? | Sexually transmitted diseases 20060901 |
| Single-dose famciclovir for the treatment of herpes labialis. | Current medical research and opinion 20060901 |
| Simultaneous modulation of transport and metabolism of acyclovir prodrugs across rabbit cornea: An approach involving enzyme inhibitors. | International journal of pharmaceutics 20060831 |
| Management of herpes simplex virus type 2 infection in HIV type 1-infected persons. | Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20060801 |
| Topical iontophoresis of valaciclovir hydrochloride improves cutaneous aciclovir delivery. | Pharmaceutical research 20060801 |
| Validation of the genital herpes treatment satisfaction questionnaire (GHerpTSQ) in status and change versions. | Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation 20060801 |
| Treatment of acute retinal necrosis syndrome. | Drugs of today (Barcelona, Spain : 1998) 20060801 |
| Stability of valacyclovir: implications for its oral bioavailability. | International journal of pharmaceutics 20060706 |
| Herpes simplex virus-1 (HSV-1) infection in radiation-induced oral mucositis. | Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer 20060701 |
| Improvement of postherpetic neuralgia after treatment with intravenous acyclovir followed by oral valacyclovir. | Archives of neurology 20060701 |
| Anti-cytomegalovirus prophylaxis in solid-organ transplant recipients. | Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases 20060701 |
| Valacyclovir prophylaxis to prevent recurrent herpes at delivery: a randomized clinical trial. | Obstetrics and gynecology 20060701 |
| Easing the pain of shingles. | Health news (Waltham, Mass.) 20060701 |
| The impact of cytomegalovirus disease and asymptomatic infection on acute renal allograft rejection. | Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology 20060601 |
| Valacyclovir for the treatment of genital herpes. | Expert review of anti-infective therapy 20060601 |
| Progress report on phase I/II clinical trial of Ad-OC-TK plus VAL therapy for metastatic or locally recurrent prostate cancer: Initial experience at Kobe University. | International journal of urology : official journal of the Japanese Urological Association 20060601 |
| Chickenpox in pregnancy: revisited. | Reproductive toxicology (Elmsford, N.Y.) 20060501 |
| Adverse neuropsychiatric effects of cytomegalovirus prophylaxis with valaciclovir in renal transplant recipients. | Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20060501 |
| Sustained long-term immune responses after in situ gene therapy combined with radiotherapy and hormonal therapy in prostate cancer patients. | International journal of radiation oncology, biology, physics 20060501 |
| The aciclovir metabolite CMMG is detectable in the CSF of subjects with neuropsychiatric symptoms during aciclovir and valaciclovir treatment. | The Journal of antimicrobial chemotherapy 20060501 |
| Herpes simplex virus type 1 colitis in a patient with common variable immunodeficiency syndrome. | European journal of gastroenterology & hepatology 20060501 |
| Evidence that amphotericin B mediates reactivation of latent Epstein-Barr virus in Hodgkin's lymphoma allowing cytotoxicity by acyclovir. | Yonsei medical journal 20060430 |
| The functional evaluation of human peptide/histidine transporter 1 (hPHT1) in transiently transfected COS-7 cells. | European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20060401 |
| Two cases of varicella zoster virus meningitis found in pediatric patients after bone marrow transplantation despite valaciclovir prophylaxis and without skin lesions. | Journal of medical virology 20060401 |
| Genital herpes: antiviral therapy for symptom relief and prevention of transmission. | Expert opinion on pharmacotherapy 20060401 |
| Prophylactic perioperative antiviral therapy for LASIK in patients with inactive herpetic keratitis. | Journal of refractive surgery (Thorofare, N.J. : 1995) 20060401 |
| Strategies in the management of alemtuzumab-related side effects. | Seminars in oncology 20060401 |
| Prevention of cytomegalovirus infection by valaciclovir after allogeneic bone marrow transplantation from an unrelated donor. | International journal of hematology 20060401 |
| [What is your diagnosis? The examination shows peripheral facial paresis]. | Praxis 20060329 |
| Renal failure with herpes simplex. | Journal of the European Academy of Dermatology and Venereology : JEADV 20060301 |
| [Infections with herpes simplex and varicella-zoster viruses during pregnancy]. | Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete 20060301 |
| Valacyclovir therapy to reduce recurrent genital herpes in pregnant women. | American journal of obstetrics and gynecology 20060301 |
| The treatment of facial palsy from the point of view of physical and rehabilitation medicine. | Europa medicophysica 20060301 |
| [Update in the treatment of herpes zoster]. | Actas dermo-sifiliograficas 20060301 |
| [Treatment of alpha-herpes virus infections]. | Nihon rinsho. Japanese journal of clinical medicine 20060301 |
| [Treatment of alpha herpesvirus infections in ophthalmology]. | Nihon rinsho. Japanese journal of clinical medicine 20060301 |
| [Suppressive therapy for genital herpes simplex virus infections]. | Nihon rinsho. Japanese journal of clinical medicine 20060301 |
| Imiquimod 5% cream for the treatment of recurrent, acyclovir-resistant genital herpes. | Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20060215 |
| High dosage of oral valaciclovir as an alternative treatment of varicella zoster acute retinal necrosis syndrome. | Eye (London, England) 20060201 |
| Pre-transplant ganciclovir and post transplant high-dose valacyclovir reduce CMV infections after alemtuzumab-based conditioning. | Bone marrow transplantation 20060201 |
| Severe erythema multiforme responding to interferon alfa. | Journal of the American Academy of Dermatology 20060201 |
| Etanercept monotherapy for a patient with psoriasis, psoriatic arthritis, and concomitant hepatitis C infection. | Journal of the American Academy of Dermatology 20060201 |
| Prophylactic valacyclovir to prevent outbreaks of primary herpes gladiatorum at a 28-day wrestling camp. | Japanese journal of infectious diseases 20060201 |
| Another case of PORN (bilateral progressive outer retinal necrosis) after allogeneic stem cell transplantation. | Bone marrow transplantation 20060101 |
| Antiviral prodrugs - the development of successful prodrug strategies for antiviral chemotherapy. | British journal of pharmacology 20060101 |
| Comparison of efficacy of oral valacyclovir and topical acyclovir in the treatment of herpes simplex keratitis: a randomized clinical trial. | Chemotherapy 20060101 |
| Viral infections affecting the skin in organ transplant recipients: epidemiology and current management strategies. | American journal of clinical dermatology 20060101 |
| Herpes encephalitis presenting as mild aphasia: case report. | BMC family practice 20060101 |
| An unusual cause of alveolar hemorrhage post hematopoietic stem cell transplantation: a case report. | BMC cancer 20060101 |
| Trial shows HSV-2 suppression can reduce HIV shedding. | IAVI report : newsletter on international AIDS vaccine research 20060101 |
| Characterization of the IFN-gamma T-cell responses to immediate early antigens in humans with genital herpes. | Virology journal 20060101 |
| [Varicella-zoster virus infections--2: Zoster pain -- therapy and prevention]. | MMW Fortschritte der Medizin 20060101 |
| In vivo ocular pharmacokinetics of acyclovir dipeptide ester prodrugs by microdialysis in rabbits. | Molecular pharmaceutics 20060101 |
| Lichen amyloidosus without itching indicates that it is not secondary to chronic scratching. | Acta dermato-venereologica 20060101 |
| Famciclovir: a review of its use in herpes zoster and genital and orolabial herpes. | Drugs 20060101 |
| Presence of Epstein-Barr virus and human herpesvirus 6B DNA in multiple sclerosis patients: associations with disease activity. | Acta neurologica Scandinavica 20051201 |
| Cytomegalovirus DNAemia and disease: incidence, natural history and management in settings other than allogeneic stem cell transplantation. | Haematologica 20051201 |
| Herpes zoster ophthalmicus: presenting as giant-cell arteritis. | Clinical & experimental ophthalmology 20051201 |
| Infections in the elderly. | Dermatology online journal 20051201 |
| Postherpetic neuralgia. | Clinical evidence 20051201 |
| Genital herpes. | Clinical evidence 20051201 |
| Herpes labialis. | Clinical evidence 20051201 |
| HSV-2 suppression reduces HIV and HSV shedding. | GMHC treatment issues : the Gay Men's Health Crisis newsletter of experimental AIDS therapies 20051201 |
| Acute renal failure and severe neurotoxicity following valacyclovir. | Intensive care medicine 20051101 |
| Management of recurrent genital herpes: a survey of UK genitourinary medicine clinics in 2003. | International journal of STD & AIDS 20051101 |
| Antiviral medications for preventing cytomegalovirus disease in solid organ transplant recipients. | The Cochrane database of systematic reviews 20051019 |
| Varicella-zoster-virus folliculitis promoted clonal cutaneous lymphoid hyperplasia. | The American Journal of dermatopathology 20051001 |
| Reducing the risk of transmitting genital herpes: advances in understanding and therapy. | Current medical research and opinion 20051001 |
| Observations on recovery from and recurrence of HSV-2 infections in adult mice that were rescued from lethal vaginal infection by antiviral therapy. | Archives of virology 20050901 |
| Idiopathic facial paralysis (Bell's palsy) in the immediate puerperium in a patient with mild preeclampsia: a case report. | Archives of gynecology and obstetrics 20050901 |
| Varicella zoster virus (VZV)-related progressive outer retinal necrosis (PORN) after allogeneic stem cell transplantation. | Bone marrow transplantation 20050901 |
| Successful renal transplantation during pregnancy. | American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20050901 |
| A comparative randomised study of valacyclovir vs. oral ganciclovir for cytomegalovirus prophylaxis in renal transplant recipients. | Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases 20050901 |
| Valacyclovir to expedite the clearance of recurrent herpes gladiatorum. | Clinical journal of sport medicine : official journal of the Canadian Academy of Sport Medicine 20050901 |
| Genital lesions in a woman with AIDS. | The AIDS reader 20050901 |
| Murine cytomegalovirus resistant to antivirals has genetic correlates with human cytomegalovirus. | The Journal of general virology 20050801 |
| Lymphocytic myocarditis after lung transplantation. | The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 20050801 |
| Main adult herpes virus infections of the CNS. | Expert review of anti-infective therapy 20050801 |
| Herpes zoster: medical and nursing management. | Clinical journal of oncology nursing 20050801 |
| Recurrent antiviral-resistant genital herpes in an immunocompetent patient. | The Journal of infectious diseases 20050701 |
| Splenectomy for severe autoimmune cytopenias after allogenic stem cell transplantation: case report. | International journal of hematology 20050701 |
| [Arguments favouring the pharmacotherapy of Bells' palsy]. | Nederlands tijdschrift voor geneeskunde 20050625 |
| Progression of varicella-zoster virus necrotizing retinopathy in an HIV-negative patient with transient immune deviation. | Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie 20050601 |
| The cost-effectiveness of prophylaxis with valaciclovir in the management of cytomegalovirus after renal transplantation. | The European journal of health economics : HEPAC : health economics in prevention and care 20050601 |
| Treatment of plantar warts with oral valacyclovir. | The American journal of medicine 20050601 |
| A randomized clinical trial of valacyclovir in multiple sclerosis. | Multiple sclerosis (Houndmills, Basingstoke, England) 20050601 |
| Antiviral medications to prevent cytomegalovirus disease and early death in recipients of solid-organ transplants: a systematic review of randomised controlled trials. | Lancet (London, England) 20050601 |
| Genital herpes. | Clinical evidence 20050601 |
| A case of Ramsay Hunt-like syndrome caused by herpes simplex virus type 2. | Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20050515 |
| [Complete ophthalmoplegia complicating ophthalmic herpes zoster]. | Revue neurologique 20050501 |
| Drugs for non-HIV viral infections. | Treatment guidelines from the Medical Letter 20050401 |
| Renal tubular transporters and antiviral drugs: an update. | AIDS (London, England) 20050325 |
| [Treatment of facial paresis--evidence-based recommendations]. | Lakartidningen 20050301 |
| Valacyclovir for cytomegalovirus prophylaxis reduces the risk of acute renal allograft rejection. | Transplantation 20050215 |
| Agents and strategies in development for improved management of herpes simplex virus infection and disease. | Expert opinion on investigational drugs 20050201 |
| Valacyclovir for the management of herpes viral infections. | Skin therapy letter 20050201 |
| Evaluation of the fibroblast growth factor system as a potential target for therapy in human prostate cancer. | British journal of cancer 20050131 |
| [Infectious diseases in the ambulatory care setting]. | Revue medicale suisse 20050112 |
| Effect of formulary policy decisions on antimicrobial drug utilization in British Columbia. | The Journal of antimicrobial chemotherapy 20050101 |
| Molecular mechanisms of severe acute respiratory syndrome (SARS). | Respiratory research 20050101 |
| [How contagious is herpes?]. | Medizinische Monatsschrift fur Pharmazeuten 20050101 |
| A case of Kaposi varicelliform eruption in Darier-White disease. | Cutis 20050101 |
| Amplification of autoimmune disease by infection. | Arthritis research & therapy 20050101 |
| [Valaciclovir-related neuro- and nephro-toxicity in two geriatric patients]. | Giornale italiano di nefrologia : organo ufficiale della Societa italiana di nefrologia 20050101 |
| Amino acid ester prodrugs of the anticancer agent gemcitabine: synthesis, bioconversion, metabolic bioevasion, and hPEPT1-mediated transport. | Molecular pharmaceutics 20050101 |
| [Antiherpetic therapy]. | Oftalmologia (Bucharest, Romania : 1990) 20050101 |
| A case of Epstein-Barr virus infection complicated with Guillain-Barré syndrome involving several cranial nerves. | Scandinavian journal of infectious diseases 20050101 |
| Prospective comparison of valacyclovir and oral ganciclovir for prevention of cytomegalovirus disease in high-risk renal transplant recipients. | Kidney & blood pressure research 20050101 |
| Permeability dominates in vivo intestinal absorption of P-gp substrate with high solubility and high permeability. | Molecular pharmaceutics 20050101 |
| Detection, quantification and genotyping of Herpes Simplex Virus in cervicovaginal secretions by real-time PCR: a cross sectional survey. | Virology journal 20050101 |
| Herpes simplex virus keratitis after laser in situ keratomileusis. | Journal of refractive surgery (Thorofare, N.J. : 1995) 20050101 |
| Immunosenescence and vaccination. | Immunity & ageing : I & A 20050101 |
| Famciclovir for the management of genital herpes simplex in patients with inadequate response to aciclovir or valaciclovir. | Clinical drug investigation 20050101 |
| Therapy of hearing disorders - conservative procedures. | GMS current topics in otorhinolaryngology, head and neck surgery 20050101 |
| Procedures for restoring vestibular disorders. | GMS current topics in otorhinolaryngology, head and neck surgery 20050101 |
| Discovery and development of BVDU (brivudin) as a therapeutic for the treatment of herpes zoster. | Biochemical pharmacology 20041215 |
| Epidural blood patch and acute varicella. | Anesthesia and analgesia 20041201 |
| Acyclovir prodrug for the intestinal di/tri-peptide transporter PEPT1: comparison of in vivo bioavailability in rats and transport in Caco-2 cells. | European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20041201 |
| Antiviral treatment of genital herpes. | International journal of STD & AIDS 20041201 |
| Postherpetic neuralgia. | Clinical evidence 20041201 |
| Is viral shedding a surrogate marker for transmission of genital herpes? A discussion document. | Herpes : the journal of the IHMF 20041201 |
| Management of CMV infection and disease in transplant patients. 27-29 February 2004. | Herpes : the journal of the IHMF 20041201 |
| Methylprednisolone, valacyclovir, or both for vestibular neuritis. | The New England journal of medicine 20041125 |
| Methylprednisolone, valacyclovir, or both for vestibular neuritis. | The New England journal of medicine 20041125 |
| Methylprednisolone, valacyclovir, or both for vestibular neuritis. | The New England journal of medicine 20041125 |
| Pharmacokinetics of novel dipeptide ester prodrugs of acyclovir after oral administration: intestinal absorption and liver metabolism. | The Journal of pharmacology and experimental therapeutics 20041101 |
| Recent developments in the management of herpes simplex virus infection in HIV-infected persons. | Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20041101 |
| Efficacy and safety of valacyclovir for the suppression and episodic treatment of herpes simplex virus in patients with HIV. | Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20041101 |
| Oral valacyclovir as prophylaxis against herpes simplex virus reactivation during high dose chemotherapy for leukemia. | Leukemia & lymphoma 20041101 |
| ACOG practice bulletin: Clinical management guidelines for obstetrician-gynecologists, number 57, November 2004. Gynecologic herpes simplex virus infections. | Obstetrics and gynecology 20041101 |
| Steroid is effective for vestibular neuritis, valacyclovir is not. | The Journal of family practice 20041101 |
| [The mild encephalitis-hypothesis--new findings and studies]. | Psychiatrische Praxis 20041101 |
| A 33-year-old man with a facial rash. | PLoS medicine 20041101 |
| Assessing bioequivalence using genomic data. | Journal of biopharmaceutical statistics 20041101 |
| Valacyclovir and acyclovir for suppression of shedding of herpes simplex virus in the genital tract. | The Journal of infectious diseases 20041015 |
| New strategies for the diagnosis, treatment, and prevention of herpes simplex in contact sports. | Current sports medicine reports 20041001 |
| Treatment of postherpetic neuralgia. | Skin therapy letter 20041001 |
| [Epilepticus status and valaciclovir in chronic renal failure]. | Medicina clinica 20040925 |
| Valacyclovir treatment ameliorates the persistently increased pentylenetetrazol-induced seizure susceptibility in mice with herpes simplex virus type 1 infection. | Experimental neurology 20040901 |
| Conjugal transfer vaccinia. | Journal of the American Academy of Dermatology 20040901 |
| The efficacy of valacyclovir in preventing recurrent herpes simplex virus infections associated with dental procedures. | Journal of the American Dental Association (1939) 20040901 |
| Detection of ganciclovir resistance after valacyclovir-prophylaxis in renal transplant recipients with active cytomegalovirus infection. | Journal of medical virology 20040801 |
| 80-year-old man with fever and ear pain. | Mayo Clinic proceedings 20040801 |
| Prevention of herpes simplex virus type 2 transmission with antiviral therapy. | Herpes : the journal of the IHMF 20040801 |
| [Preparation of valaciclovir loaded bovine serum albumin nanoparticles surface-modified with glycyrrhizin and its characteristics of targeting to liver]. | Sheng wu yi xue gong cheng xue za zhi = Journal of biomedical engineering = Shengwu yixue gongchengxue zazhi 20040801 |
| HSV shedding. | Antiviral research 20040801 |
| HSV-2 transmission. | Antiviral research 20040801 |
| [A 59-year old patient with herpes zoster V1-V2]. | Praxis 20040728 |
| Methylprednisolone, valacyclovir, or the combination for vestibular neuritis. | The New England journal of medicine 20040722 |
| Persistence and transition of Epstein-Barr virus genotypes in the pathogenesis of oral hairy leukoplakia. | The Journal of infectious diseases 20040715 |
| Expression of Epstein-Barr virus latent genes in oral epithelium: determinants of the pathogenesis of oral hairy leukoplakia. | The Journal of infectious diseases 20040715 |
| Antiviral treatment of genital herpes. | International journal of STD & AIDS 20040701 |
| Valtrex therapy for Epstein-Barr virus reactivation and upper respiratory symptoms in elite runners. | Medicine and science in sports and exercise 20040701 |
| Transport of amino acid esters and the amino-acid-based prodrug valganciclovir by the amino acid transporter ATB(0,+). | Pharmaceutical research 20040701 |
| Therapeutic options for herpes labialis, I: Oral agents. | Cutis 20040701 |
| Antiviral drugs in current clinical use. | Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology 20040601 |
| Pharmacokinetics of valaciclovir. | The Journal of antimicrobial chemotherapy 20040601 |
| A decision-analytic economic evaluation of valaciclovir prophylaxis for the prevention of cytomegalovirus infection and disease in renal transplantation. | Clinical transplantation 20040601 |
| Enhanced systemic T-cell activation after in situ gene therapy with radiotherapy in prostate cancer patients. | International journal of radiation oncology, biology, physics 20040601 |
| Epstein-Barr virus load correlating with clinical manifestation and treatment response in a patient with angioimmunoblastic T-cell lymphoma. | Antiviral therapy 20040601 |
| Herpes simplex virus infections of the central nervous system: encephalitis and meningitis, including Mollaret's. | Herpes : the journal of the IHMF 20040601 |
| Vasculitic mononeuritis multiplex induced by valacyclovir. | Neurology 20040525 |
| Clinical significance of antiviral therapy for episodic treatment of herpes labialis: exploratory analyses of the combined data from two valaciclovir trials. | The Journal of antimicrobial chemotherapy 20040501 |
| Effect of Epstein-Barr virus replication on Langerhans cells in pathogenesis of oral hairy leukoplakia. | The Journal of infectious diseases 20040501 |
| Failure of valacyclovir for herpes zoster in a moderately immunocompromised HIV-infected patient. | AIDS patient care and STDs 20040501 |
| A pilot study of alemtuzumab (anti-CD52 monoclonal antibody) therapy for patients with relapsed or chemotherapy-refractory peripheral T-cell lymphomas. | Blood 20040415 |
| Oral antivirals for the acute treatment of recurrent herpes labialis. | The Annals of pharmacotherapy 20040401 |
| Phase I-II trial evaluating combined intensity-modulated radiotherapy and in situ gene therapy with or without hormonal therapy in treatment of prostate cancer-interim report on PSA response and biopsy data. | International journal of radiation oncology, biology, physics 20040401 |
| No effect of antiviral (valacyclovir) treatment in fibromyalgia: a double blind, randomized study. | The Journal of rheumatology 20040401 |
| Childhood shingles. Herpes zoster can occur in healthy children too. | Postgraduate medicine 20040401 |
| Transport of amino acid-based prodrugs by the Na+- and Cl(-) -coupled amino acid transporter ATB0,+ and expression of the transporter in tissues amenable for drug delivery. | The Journal of pharmacology and experimental therapeutics 20040301 |
| Cases from the Osler Medical Service at Johns Hopkins University. | The American journal of medicine 20040301 |
| [Arcuate keratotomy to correct residual astigmatism after stromal herpetic keratitis]. | Archivos de la Sociedad Espanola de Oftalmologia 20040301 |
| The effect of valacyclovir treatment on natural killer cells of infertile women. | American journal of reproductive immunology (New York, N.Y. : 1989) 20040301 |
| Drug approval highlights for 2003. | The Nurse practitioner 20040201 |
| Peptide transporters: structure, function, regulation and application for drug delivery. | Current drug metabolism 20040201 |
| Valaciclovir for chronic hepatitis B virus infection after lung transplantation. | Infection 20040201 |
| Clostridium difficile colitis associated with valaciclovir. | Pharmacy world & science : PWS 20040201 |
| Medication error due to ambiguous labelling of a commercial product. | Pharmacy world & science : PWS 20040201 |
| Kaposi's varicelliform eruption: a case report and review of the literature. | Cutis 20040201 |
| Antiviral agents for the prevention of the sexual transmission of herpes simplex in discordant couples. | Current opinion in infectious diseases 20040201 |
| Neurotoxicity of acyclovir and valacyclovir in a hemodialyzed patient. | European journal of neurology 20040101 |
| Once-daily valacyclovir to reduce the risk of transmission of genital herpes. | The New England journal of medicine 20040101 |
| Use of antiviral drugs to prevent herpesvirus transmission. | The New England journal of medicine 20040101 |
| Treatment modalities and medication recommended by health care professionals for treating recurrent herpes labialis. | Journal of the American Dental Association (1939) 20040101 |
| Interrupting transmission of genital herpes. | Reviews in medical virology 20040101 |
| Evaluation of pharmacokinetic interactions after oral administration of mycophenolate mofetil and valaciclovir or aciclovir to healthy subjects. | Clinical pharmacokinetics 20040101 |
| Infectious disease capsules: a pox on your house. | Skinmed 20040101 |
| Aciclovir or valaciclovir for Bell's palsy (idiopathic facial paralysis). | The Cochrane database of systematic reviews 20040101 |
| [Up to date in sexually transmitted infections: epidemiology, diagnostic approaches and treatments]. | Enfermedades infecciosas y microbiologia clinica 20040101 |
| Treatment options: herpes simplex viruses. | Skinmed 20040101 |
| Penciclovir cream--improved topical treatment for herpes simplex infections. | Skin pharmacology and physiology 20040101 |
| Viral prophylaxis in organ transplant patients. | Drugs 20040101 |
| Allergic contact dermatitis to propolis. | Journal of drugs in dermatology : JDD 20040101 |
| A novel nucleoside prodrug-activating enzyme: substrate specificity of biphenyl hydrolase-like protein. | Molecular pharmaceutics 20040101 |
| Structure and specificity of a human valacyclovir activating enzyme: a homology model of BPHL. | Molecular pharmaceutics 20040101 |
| Disseminated tuberculosis, pulmonary aspergillosis and cutaneous herpes simplex infection in a patient with infliximab and methotrexate. | Intensive care medicine 20031201 |
| Aciclovir and valaciclovir neurotoxicity in patients with renal failure. | Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20031201 |
| Valacyclovir-induced seizures in end-stage renal disease. | The Annals of pharmacotherapy 20031201 |
| Possible valacyclovir-related neurotoxicity and aseptic meningitis. | The Annals of pharmacotherapy 20031201 |
| Short-course oral antiviral treatment for recurrent genital herpes. | The Annals of pharmacotherapy 20031201 |
| Reduction of symptoms by valacyclovir in cytomegalovirus-seropositive individuals with schizophrenia. | The American journal of psychiatry 20031201 |
| Painful genital ulcers. | The Journal of family practice 20031201 |
| Formulary considerations for drugs used to prevent cytomegalovirus disease. | American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20031201 |
| HIV: prevention of opportunistic infections. | Clinical evidence 20031201 |
| Dosing schedule of oral valacyclovir for prevention of herpes simplex virus. | Bone marrow transplantation 20031101 |
| The epidemiology and clinical analysis of several outbreaks of herpes gladiatorum. | Medicine and science in sports and exercise 20031101 |
| Chronic graft-versus-host disease following varicella-zoster virus infection in allogeneic stem cell transplant recipients. | International journal of hematology 20031101 |
| [Advances in epidemiology, diagnosis and treatment of genital herpes]. | Zhonghua nan ke xue = National journal of andrology 20031101 |
| Low-dose valaciclovir prophylaxis against cytomegalovirus disease in renal transplant recipients. | Transplant international : official journal of the European Society for Organ Transplantation 20031001 |
| Valacyclovir for the suppression of recurrent genital herpes in human immunodeficiency virus-infected subjects. | The Journal of infectious diseases 20031001 |
| Epstein-Barr virus replication in oral hairy leukoplakia: response, persistence, and resistance to treatment with valacyclovir. | The Journal of infectious diseases 20030915 |
| Recurrent herpes simplex labialis: selected therapeutic options. | Journal (Canadian Dental Association) 20030901 |
| Nonnecrotizing herpetic retinopathies masquerading as severe posterior uveitis. | Ophthalmology 20030901 |
| Profiling penciclovir susceptibility and prevalence of resistance of herpes simplex virus isolates across eleven clinical trials. | Archives of virology 20030901 |
| Health-related quality of life predicts survival, cytomegalovirus disease, and study retention in clinical trial participants with advanced HIV disease. | Journal of clinical epidemiology 20030901 |
| Isolated foot ulcer complicating acute leukemia: an unusual manifestation of herpes simplex virus infection simulating pyoderma gangrenosum. | Pediatric hematology and oncology 20030901 |
| Systemic acyclovir reaction subsequent to acyclovir contact allergy: which systemic antiviral drug should then be used? | Contact dermatitis 20030901 |
| Gene expression in the human intestine and correlation with oral valacyclovir pharmacokinetic parameters. | The Journal of pharmacology and experimental therapeutics 20030801 |
| Efficacy and safety of lowering immunosuppression to treat CMV infection in renal transplant recipients on valaciclovir prophylaxis: a pilot study. | Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20030801 |
| Antiviral therapy in children with varicella zoster virus and herpes simplex virus infections. | Herpes : the journal of the IHMF 20030801 |
| Review of antiviral therapy for herpes labialis, genital herpes and herpes zoster. | Expert review of anti-infective therapy 20030801 |
| Identification of a human valacyclovirase: biphenyl hydrolase-like protein as valacyclovir hydrolase. | The Journal of biological chemistry 20030711 |
| HIV: opportunistic infections. | Clinical evidence 20030601 |
| Herpes zoster guideline of the German Dermatology Society (DDG). | Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology 20030401 |
| Comparative study of prophylactic oral ganciclovir and valacyclovir in high-risk kidney transplant recipients. | Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20030401 |
| Analysis of numbers of repeated units in R2 region among varicella-zoster virus strains. | Journal of dermatological science 20030401 |
| A neutropenia suggesting an interaction between valacyclovir and mycophenolate mofetil. | Clinical transplantation 20030401 |
| Bell's palsy. Early treatment with antiviral medications and corticosteroids may improve the chances for full recovery from this condition that suddenly paralyzes one side of the face. | Harvard health letter 20030401 |
| [A different headache]. | Praxis 20030319 |
| Randomized comparison of oral valacyclovir and intravenous ganciclovir for prevention of cytomegalovirus disease after allogeneic bone marrow transplantation. | Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20030315 |
| Patients' preference of valacyclovir once-daily suppressive therapy versus twice-daily episodic therapy for recurrent genital herpes: a randomized study. | Sexually transmitted diseases 20030301 |
| [Herpetic folliculitis barbae. A rare cause of folliculitis]. | Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete 20030301 |
| Outcome of treatment with valacyclovir and prednisone in patients with Bell's palsy. | The Annals of otology, rhinology, and laryngology 20030301 |
| Valacyclovir for prevention of recurrent herpes labialis: 2 double-blind, placebo-controlled studies. | Cutis 20030301 |
| Phase I dose escalation clinical trial of adenovirus vector carrying osteocalcin promoter-driven herpes simplex virus thymidine kinase in localized and metastatic hormone-refractory prostate cancer. | Human gene therapy 20030210 |
| Novel agents and strategies to treat herpes simplex virus infections. | Expert opinion on investigational drugs 20030201 |
| Nodular perianal herpes simplex with prominent plasma cell infiltration. | Sexually transmitted diseases 20030201 |
| Neurological disturbances with valaciclovir. | Prescrire international 20030201 |
| B-virus (Cercopithecine herpesvirus 1) infection in humans and macaques: potential for zoonotic disease. | Emerging infectious diseases 20030201 |
| [Anti-herpetic chemotherapeutic drugs]. | Nihon rinsho. Japanese journal of clinical medicine 20030201 |
| Prodrugs of purine and pyrimidine analogues for the intestinal di/tri-peptide transporter PepT1: affinity for hPepT1 in Caco-2 cells, drug release in aqueous media and in vitro metabolism. | Journal of controlled release : official journal of the Controlled Release Society 20030117 |
| Valacyclovir for the prevention of cytomegalovirus infection after kidney transplantation is associated with macrocytosis. | American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20030101 |
| Valaciclovir as a single dose during prodrome of herpes facialis: a pilot randomized double-blind clinical trial. | The British journal of dermatology 20030101 |
| Clinical utility of oral valacyclovir compared with oral acyclovir for the prevention of herpes simplex virus mucositis following autologous bone marrow transplantation or stem cell rescue therapy. | Bone marrow transplantation 20030101 |
| A study of shingles and the development of postherpetic neuralgia in East London. | Journal of medical virology 20030101 |
| The role of antivirals in the management of neuropathic pain in the older patient with herpes zoster. | Drugs & aging 20030101 |
| [The state-of-the art and prospects for the pharmacological therapy of infectious and allergic eye diseases]. | Vestnik Rossiiskoi akademii meditsinskikh nauk 20030101 |
| Novel dipeptide prodrugs of acyclovir for ocular herpes infections: Bioreversion, antiviral activity and transport across rabbit cornea. | Current eye research 20030101 |
| Recurrent genital herpes treatments and their impact on quality of life. | PharmacoEconomics 20030101 |
| Inhibition of sickling in vitro by three purine-based antiviral agents: an approach to the treatment of sickle cell disease. | Blood cells, molecules & diseases 20030101 |
| Valacyclovir in the treatment of herpes simplex, herpes zoster, and other viral infections. | Journal of cutaneous medicine and surgery 20030101 |
| Cutaneous infections in the elderly: diagnosis and management. | Dermatologic therapy 20030101 |
| Changing paradigms in dermatology: antivirals in dermatology. | Clinics in dermatology 20030101 |
| First one-day, oral antiviral for cold sores is approved. | Dental assistant (Chicago, Ill. : 1994) 20030101 |
| [Clinical forms and treatment of keratitis caused by varicella-zoster virus]. | Vestnik oftalmologii 20030101 |
| Labeling updates to genital herpes drug. | FDA consumer 20030101 |
| Infection fighters. Valtrex suppresses herpes outbreaks. | TreatmentUpdate 20030101 |
| Infection fighters. High-dose Valtrex for oral hairy leukoplakia. | TreatmentUpdate 20030101 |
| Contemporary antiviral drug regimens for the prevention and treatment of orolabial and anogenital herpes simplex virus infection in the normal host: Four approved indications and 13 off-label uses. | The Canadian journal of infectious diseases = Journal canadien des maladies infectieuses 20030101 |
| Aborted genital herpes simplex virus lesions: findings from a randomised controlled trial with valaciclovir. | Sexually transmitted infections 20021201 |
| Successful use of valciclovir in a case of recurrent urticaria associated with genital herpes. | Sexually transmitted infections 20021201 |
| A randomized prospective controlled trial of oral ganciclovir versus oral valacyclovir for prophylaxis of cytomegalovirus disease after renal transplantation. | Transplant international : official journal of the European Society for Organ Transplantation 20021201 |
| [Clinical and epidemiological aspects and current recommendations on treatment of genital herpes]. | Voenno-meditsinskii zhurnal 20021201 |
| Recommendations for prevention of and therapy for exposure to B virus (cercopithecine herpesvirus 1). | Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20021115 |
| Valacyclovir (valtrex) for herpes labialis. | The Medical letter on drugs and therapeutics 20021111 |
| Valacyclovir and famciclovir therapy in herpes zoster. | Current neurology and neuroscience reports 20021101 |
| Lowering immunosuppression is safe and effective to treat altered pattern of CMV infection in renal transplant recipients on valaciclovir prophylaxis. | Transplantation proceedings 20021101 |
| Evaluation and management of herpes zoster ophthalmicus. | American family physician 20021101 |
| Extending the boundaries of Herpesvirus infections: advances in therapy. Malta, 12 November 2000. Proceedings of a conference. | The Journal of infectious diseases 20021015 |
| Challenges in genital herpes simplex virus management. | The Journal of infectious diseases 20021015 |
| Valacyclovir for herpes simplex virus infection: long-term safety and sustained efficacy after 20 years' experience with acyclovir. | The Journal of infectious diseases 20021015 |
| Progress in meeting today's demands in genital herpes: an overview of current management. | The Journal of infectious diseases 20021015 |
| Valacyclovir in the treatment of facial herpes simplex virus infection. | The Journal of infectious diseases 20021015 |
| Clinical manifestations and treatment considerations of herpes simplex virus infection. | The Journal of infectious diseases 20021015 |
| Understanding pain in herpes zoster: an essential for optimizing treatment. | The Journal of infectious diseases 20021015 |
| Beta-herpesvirus challenges in the transplant recipient. | The Journal of infectious diseases 20021015 |
| Valacyclovir provides optimum acyclovir exposure for prevention of cytomegalovirus and related outcomes after organ transplantation. | The Journal of infectious diseases 20021015 |
| The economic value of valacyclovir prophylaxis in transplantation. | The Journal of infectious diseases 20021015 |
| An investigation of the steady-state pharmacokinetics of oral valacyclovir in immunocompromised children. | The Journal of infectious diseases 20021015 |
| Tomorrow's challenges for herpesvirus management: potential applications of valacyclovir. | The Journal of infectious diseases 20021015 |
| Prevention of cytomegalovirus disease in hematopoietic stem cell transplantation. | Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20021015 |
| Microbiology. Domino effects from battles against microbes. | Science (New York, N.Y.) 20021011 |
| Valacyclovir versus acyclovir for HSV prophylaxisin neutropenic patients. | The Annals of pharmacotherapy 20021001 |
| Topical 5% imiquimod for the therapy of actinic cheilitis. | Journal of the American Academy of Dermatology 20021001 |
| Antiviral agents: Non-antiretroviral [correction of Nonantiviral] drugs. | Journal of the American Academy of Dermatology 20021001 |
| Prognostic factors of postherpetic neuralgia. | Journal of Korean medical science 20021001 |
| Ocular penetration of acyclovir and its peptide prodrugs valacyclovir and val-valacyclovir following systemic administration in rabbits: An evaluation using ocular microdialysis and LC-MS. | Current eye research 20021001 |
| Verrucous herpes of the scrotum in a human immunodeficiency virus-positive man: case report and review of the literature. | Journal of the European Academy of Dermatology and Venereology : JEADV 20020901 |
| [Drugs against human cytomegalovirus]. | Polski merkuriusz lekarski : organ Polskiego Towarzystwa Lekarskiego 20020901 |
| [Herpes zoster of the maxillary branch of the trigeminal nerve]. | Presse medicale (Paris, France : 1983) 20020824 |
| Valacyclovir neurotoxicity in a patient with end-stage renal disease treated with continuous ambulatory peritoneal dialysis. | Clinical nephrology 20020801 |
| Mechanism of corneal permeation of L-valyl ester of acyclovir: targeting the oligopeptide transporter on the rabbit cornea. | Pharmaceutical research 20020801 |
| A six-month trial of valacyclovir in the Epstein-Barr virus subset of chronic fatigue syndrome: improvement in left ventricular function. | Drugs of today (Barcelona, Spain : 1998) 20020801 |
| Successful treatment of an aciclovir-resistant herpes simplex type 2 infection with cidofovir in an AIDS patient. | The British journal of dermatology 20020701 |
| Synthesis of analogs of L-valacyclovir and determination of their substrate activity for the oligopeptide transporter in Caco-2 cells. | European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20020701 |
| Cytomegalovirus (CMV) polymerase chain reaction profiles in individuals with advanced human immunodeficiency virus infection: relationship to CMV disease. | The Journal of infectious diseases 20020615 |
| Potent in vivo antiviral activity of the herpes simplex virus primase-helicase inhibitor BAY 57-1293. | Antimicrobial agents and chemotherapy 20020601 |
| Oral valacyclovir in the treatment of acute retinal necrosis syndrome. | Retina (Philadelphia, Pa.) 20020601 |
| Recurrent herpes simplex virus type 2 meningitis: a case report of Mollaret's meningitis. | Japanese journal of infectious diseases 20020601 |
| Treatment of sudden sensorineural hearing loss with systemic steroids and valacyclovir. | Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology 20020501 |
| Anti-viral prophylaxis reduces the incidence of lymphoproliferative disease in lung transplant recipients. | The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 20020501 |
| Evaluation of valaciclovir dosage reduction in continuous ambulatory peritoneal dialysis patients. | Nephron 20020501 |
| [Valaciclovir]. | Annales de dermatologie et de venereologie 20020501 |
| Randomized study of valacyclovir as prophylaxis against cytomegalovirus reactivation in recipients of allogeneic bone marrow transplants. | Blood 20020415 |
| Temporal pattern of herpes simplex virus type 1 infection and cell death in the mouse brain stem: influence of guanosine nucleoside analogues. | Journal of virological methods 20020401 |
| Valacyclovir for episodic treatment of genital herpes: a shorter 3-day treatment course compared with 5-day treatment. | Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20020401 |
| Challenges and options in the management of viral infections after stem cell transplantation. | Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer 20020401 |
| Pharmacokinetics of acyclovir in immunocompromized children with leukopenia and mucositis after chemotherapy: can intravenous acyclovir be substituted by oral valacyclovir? | Medical and pediatric oncology 20020401 |
| Valacyclovir prevention of cytomegalovirus reactivation after heart transplantation: a randomized trial. | The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 20020401 |
| Valacyclovir prophylaxis for herpes simplex virus infection or infection recurrence following laser skin resurfacing. | Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.] 20020401 |
| [Genital herpes: epidemiology, transmission, clinic, asymptomatic viral excretion, impact on other sexually transmitted diseases, prevention, and treatment]. | Annales de dermatologie et de venereologie 20020401 |
| [National survey of dermatologists]. | Annales de dermatologie et de venereologie 20020401 |
| [National survey of gynecologists-obstetricians and general practitioners]. | Annales de dermatologie et de venereologie 20020401 |
| [Antiviral and non-antiviral general treatments for oro-facial and genital herpes (pregnancy and neonates excluded)]. | Annales de dermatologie et de venereologie 20020401 |
| [Perspectives for the treatment and prevention of herpes simplex infections]. | Annales de dermatologie et de venereologie 20020401 |
| Acute herpetic gingivostomatitis in adults: a review of 13 cases, including diagnosis and management. | Journal (Canadian Dental Association) 20020401 |
| Human organic anion transporters and human organic cation transporters mediate renal antiviral transport. | The Journal of pharmacology and experimental therapeutics 20020301 |
| Syntheses, chemical and enzymatic stability of new poly(ethylene glycol)-acyclovir prodrugs. | Farmaco (Societa chimica italiana : 1989) 20020301 |
| Drugs for non-HIV viral infections. | The Medical letter on drugs and therapeutics 20020204 |
| Valacyclovir prophylaxis for the prevention of Herpes simplex virus reactivation in recipients of progenitor cells transplantation. | Bone marrow transplantation 20020201 |
| New treatments for genital herpes. | Current opinion in infectious diseases 20020201 |
| Cutaneous HSV-2 infection with serial recurrences at multiple sites. | International journal of dermatology 20020201 |
| A randomized, double-blind, placebo-controlled MRI study of anti-herpes virus therapy in MS. | Neurology 20020108 |
| Valacyclovir in the treatment of genital herpes and herpes zoster. | Expert opinion on pharmacotherapy 20020101 |
| Valaciclovir versus aciclovir for herpes simplex virus infection in HIV-infected individuals: two randomized trials. | International journal of STD & AIDS 20020101 |
| [Molecular mechanisms on drug transporters in the drug absorption and disposition]. | Nihon rinsho. Japanese journal of clinical medicine 20020101 |
| Acyclovir concentrations in human breast milk after valaciclovir administration. | American journal of obstetrics and gynecology 20020101 |
| Viral diseases of the skin: diagnosis and antiviral treatment. | Paediatric drugs 20020101 |
| [Neurotoxicity after the first dose of oral administration of valaciclovir in a female hemodialyzed patient]. | Nefrologia : publicacion oficial de la Sociedad Espanola Nefrologia 20020101 |
| Current management strategies for the prevention and treatment of cytomegalovirus infection in pediatric transplant recipients. | Paediatric drugs 20020101 |
| Genital herpes simplex virus infection in the adolescent: special considerations for management. | Paediatric drugs 20020101 |
| Adenovirus-mediated thymidine kinase gene therapy for recurrent ovarian cancer: expression of coxsackie-adenovirus receptor and integrins alphavbeta3 and alphavbeta5. | Journal of the Society for Gynecologic Investigation 20020101 |
| Antiviral agents in women's health: pharmacotherapeutics of treating influenza and herpes. | Journal of midwifery & women's health 20020101 |
| European best practice guidelines for renal transplantation. Section IV: Long-term management of the transplant recipient. IV.6.1. Cancer risk after renal transplantation. Post-transplant lymphoproliferative disease (PTLD): prevention and treatment. | Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20020101 |
| Prophylaxis of herpesvirus infections in immunocompetent and immunocompromised older patients. | Drugs & aging 20020101 |
| Herpes simplex virus infection. | Seminars in pediatric infectious diseases 20020101 |
| Viral skin infections in the elderly: diagnosis and management. | Drugs & aging 20020101 |
| [Necrosis of the nose tip]. | Duodecim; laaketieteellinen aikakauskirja 20020101 |
| Acyclovir for treating varicella in otherwise healthy children and adolescents: a systematic review of randomised controlled trials. | BMC pediatrics 20020101 |
| Oral antivirals revisited in the treatment of herpes zoster: what do they accomplish? | American journal of clinical dermatology 20020101 |
| Pharmacokinetics and safety of valaciclovir in children with Epstein-Barr virus illness. | Drugs in R&D 20020101 |
| Oral valacyclovir versus intravenous acyclovir in preventing herpes simplex virus infections in autologous stem cell transplant recipients. | Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation 20020101 |
| Persistent productive Epstein-Barr virus replication in normal epithelial cells in vivo. | The Journal of infectious diseases 20011215 |
| CMV disease in CMV-mismatched renal transplant recipients with prophylactic low dose valaciclovir. | Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology 20011201 |
| Separation methods for acyclovir and related antiviral compounds. | Journal of chromatography. B, Biomedical sciences and applications 20011125 |
| Prophylaxis of cytomegalovirus infection in renal transplantation. | Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20011101 |
| Varicella in a pediatric heart transplant population on nonsteroid maintenance immunosuppression. | Pediatrics 20011101 |
| Pediatric uses of valacyclovir, penciclovir and famciclovir. | The Pediatric infectious disease journal 20011101 |
| Varicella zoster virus. Recent advances in management. | Canadian family physician Medecin de famille canadien 20011101 |
| Rapid systemic valaciclovir reaction subsequent to aciclovir contact allergy. | Contact dermatitis 20010901 |
| Infection due to acyclovir resistant herpes simplex virus in patients undergoing allogeneic hematopoietic stem cell transplantation. | Pathologie-biologie 20010901 |
| Antiviral drugs: current state of the art. | Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology 20010801 |
| Valacyclovir inhibition of recovery of ocular herpes simplex virus type 1 after experimental reactivation by laser in situ keratomileusis. | Journal of cataract and refractive surgery 20010801 |
| Valacyclovir for the prevention of cytomegalovirus infection after allogeneic stem cell transplantation: a single institution retrospective cohort analysis. | Bone marrow transplantation 20010801 |
| Antiviral agents for influenza, hepatitis C and herpesvirus, enterovirus and rhinovirus infections. | The Medical journal of Australia 20010716 |
| Comparable aciclovir exposures produced by oral valaciclovir and intravenous aciclovir in immunocompromised cancer patients. | The Journal of antimicrobial chemotherapy 20010601 |
| Choreiform movements in dialysis patient taking valacyclovir and famciclovir. | Southern medical journal 20010601 |
| Comparative study of the efficacy and safety of valaciclovir versus acyclovir in the treatment of herpes zoster. | Journal of microbiology, immunology, and infection = Wei mian yu gan ran za zhi 20010601 |
| Viral infections of the CNS with special emphasis on herpes simplex infections. | Journal of neurology 20010601 |
| [Recurrent corneal keratitis associated with the use of latanoprost]. | Archivos de la Sociedad Espanola de Oftalmologia 20010501 |
| Genvir (Flamel Technologies). | Current opinion in investigational drugs (London, England : 2000) 20010501 |
| [Peptide transporter family]. | Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme 20010401 |
| New developments in the management of cytomegalovirus infection and disease after renal transplantation. | Current opinion in urology 20010301 |
| [Neurologic toxicity caused by zelitrex (valaciclovir) in 3 patients with renal failure. Is overdose associated with improvement of product bioavailability improvement?]. | La Revue de medecine interne 20010301 |
| Drug inhibition of Gly-Sar uptake and hPepT1 localization using hPepT1-GFP fusion protein. | AAPS pharmSci 20010301 |
| Recent developments in herpesvirus therapy. | Herpes : the journal of the IHMF 20010301 |
| Longitudinal analysis of varicella-zoster virus DNA on the ocular surface associated with herpes zoster ophthalmicus. | American journal of ophthalmology 20010101 |
| Herpetic folliculitis and syringitis simulating acne excoriée. | Archives of dermatology 20010101 |
| Aseptic meningitis related to valacyclovir. | The Annals of pharmacotherapy 20010101 |
| [Valaciclovir in the treatment of initial infection by genital herpes virus: comparative study]. | Enfermedades infecciosas y microbiologia clinica 20010101 |
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