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124378-77-4 | 4-Benzofuranacetamide, N-methyl-N-[(5R,7S,8S)-7-(1-pyrrolidinyl)-1-oxaspiro[4.5]dec-8-yl]-
CAS No: 124378-77-4 Catalog No: AG000LY1 MDL No:MFCD00897252
Product Description
Catalog Number:
AG000LY1
Chemical Name:
4-Benzofuranacetamide, N-methyl-N-[(5R,7S,8S)-7-(1-pyrrolidinyl)-1-oxaspiro[4.5]dec-8-yl]-
CAS Number:
124378-77-4
Molecular Formula:
C24H32N2O3
Molecular Weight:
396.5225
MDL Number:
MFCD00897252
IUPAC Name:
2-(1-benzofuran-4-yl)-N-methyl-N-[(5R,7S,8S)-7-pyrrolidin-1-yl-1-oxaspiro[4.5]decan-8-yl]acetamide
InChI:
InChI=1S/C24H32N2O3/c1-25(23(27)16-18-6-4-7-22-19(18)9-15-28-22)20-8-11-24(10-5-14-29-24)17-21(20)26-12-2-3-13-26/h4,6-7,9,15,20-21H,2-3,5,8,10-14,16-17H2,1H3/t20-,21-,24-/m0/s1
InChI Key:
JMBYBVLCYODBJQ-HFMPRLQTSA-N
SMILES:
O=C(N([C@H]1CC[C@]2(C[C@@H]1N1CCCC1)CCCO2)C)Cc1ccc2c(o1)ccc2
UNII:
KJL283326C
Properties
Complexity:
593
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
1
Defined Atom Stereocenter Count:
3
Defined Bond Stereocenter Count:
0
Exact Mass:
396.241g/mol
Formal Charge:
0
Heavy Atom Count:
29
Hydrogen Bond Acceptor Count:
4
Hydrogen Bond Donor Count:
0
Isotope Atom Count:
0
Molecular Weight:
396.531g/mol
Monoisotopic Mass:
396.241g/mol
Rotatable Bond Count:
4
Topological Polar Surface Area:
45.9A^2
Undefined Atom Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
XLogP3:
3.4
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| Analysis of [3H]bremazocine binding in single and combinatorial opioid receptor knockout mice. | European journal of pharmacology 20010302 |
| The adrenergic receptor agonist, clonidine, potentiates the anti-parkinsonian action of the selective kappa-opioid receptor agonist, enadoline, in the monoamine-depleted rat. | British journal of pharmacology 19991201 |
| The effects of excitotoxicity on the expression of the amyloid precursor protein gene in the brain and its modulation by neuroprotective agents. | Journal of neural transmission (Vienna, Austria : 1996) 19980101 |
| Radioligand-dependent discrepancy in agonist affinities enhanced by mutations in the kappa-opioid receptor. | Molecular pharmacology 19961001 |
| CI-977, a novel and selective agonist for the kappa-opioid receptor. | British journal of pharmacology 19900901 |
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