200,000+ products from a single source!
sales@angenechem.com
123691-14-5 | Phosphinic acid, P-(3-aminopropyl)-P-(cyclohexylmethyl)-
CAS No: 123691-14-5 Catalog No: AG000KYD MDL No:
Product Description
Catalog Number:
AG000KYD
Chemical Name:
Phosphinic acid, P-(3-aminopropyl)-P-(cyclohexylmethyl)-
CAS Number:
123691-14-5
Molecular Formula:
C10H22NO2P
Molecular Weight:
219.2609
IUPAC Name:
3-aminopropyl(cyclohexylmethyl)phosphinic acid
InChI:
InChI=1S/C10H22NO2P/c11-7-4-8-14(12,13)9-10-5-2-1-3-6-10/h10H,1-9,11H2,(H,12,13)
InChI Key:
XOESDNIUAWGCLU-UHFFFAOYSA-N
SMILES:
NCCCP(=O)(CC1CCCCC1)O
Properties
Complexity:
202
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
1
Defined Atom Stereocenter Count:
0
Defined Bond Stereocenter Count:
0
Exact Mass:
219.139g/mol
Formal Charge:
0
Heavy Atom Count:
14
Hydrogen Bond Acceptor Count:
3
Hydrogen Bond Donor Count:
2
Isotope Atom Count:
0
Molecular Weight:
219.265g/mol
Monoisotopic Mass:
219.139g/mol
Rotatable Bond Count:
5
Topological Polar Surface Area:
63.3A^2
Undefined Atom Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
XLogP3:
-1.6
Literature
| Title | Journal |
|---|---|
| gamma-Aminobutyric acid-mediated regulation of the activity-dependent olfactory bulb dopaminergic phenotype. | Journal of neuroscience research 20090801 |
| Increased GABA(B) receptor-mediated signaling reduces the susceptibility of fragile X knockout mice to audiogenic seizures. | Molecular pharmacology 20090701 |
| Synaptic properties of the mammillary and cortical afferents to the anterodorsal thalamic nucleus in the mouse. | The Journal of neuroscience : the official journal of the Society for Neuroscience 20090617 |
| Effects of electrically coupled inhibitory networks on local neuronal responses to intracortical microstimulation. | Journal of neurophysiology 20060901 |
| GABAB-receptor-mediated suppression of sympathetic outflow from the spinal cord of neonatal rats. | Journal of applied physiology (Bethesda, Md. : 1985) 20051101 |
| Mapping by laser photostimulation of connections between the thalamic reticular and ventral posterior lateral nuclei in the rat. | Journal of neurophysiology 20051001 |
| Comparison of metabotropic glutamate receptor responses at segmental and descending inputs to motoneurons in neonatal rat spinal cord. | The Journal of pharmacology and experimental therapeutics 20050201 |
| GABA(B) receptor agonists reverse akinesia following intranigral or intracerebroventricular injection in the reserpine-treated rat. | British journal of pharmacology 20030802 |
| GABA(B) receptor inhibition causes locomotor stimulation in mice. | European journal of pharmacology 20011214 |
| Attenuation of morphine withdrawal signs by the GABA(B) receptor agonist baclofen. | Life sciences 20011214 |
| Repeated administration of CGP 46381, a gamma-aminobutyric acidB antagonist, and ethosuximide suppresses seizure-associated cyclic adenosine 3'5' monophosphate response element- and activator protein-1 DNA-binding activities in lethargic (lh/lh) mice. | Neuroscience letters 20010119 |
| The human GABA(B1b) and GABA(B2) heterodimeric recombinant receptor shows low sensitivity to phaclofen and saclofen. | British journal of pharmacology 20001101 |
| Characterization of the antiabsence effects of SCH 50911, a GABA-B receptor antagonist, in the lethargic mouse, gamma-hydroxybutyrate, and pentylenetetrazole models. | The Journal of pharmacology and experimental therapeutics 19950901 |
| Phosphinic acid analogues of GABA. 2. Selective, orally active GABAB antagonists. | Journal of medicinal chemistry 19950818 |
| The actions of orally active GABAB receptor antagonists on GABAergic transmission in vivo and in vitro. | European journal of pharmacology 19930323 |
Related Products
Featured Products
© 2019 Angene International Limited. All rights Reserved.