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CAS No: 12244-57-4 Catalog No: AG001790 MDL No:
Title | Journal |
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Aurothiomalate inhibits the expression of mPGES-1 in primary human chondrocytes. | Scandinavian journal of rheumatology 20150101 |
Effects of aurothiomalate and gold(III) complexes on spontaneous motility of isolated human oviduct. | Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine 20121001 |
Effect of NF-κB inhibitor aurothiomalate on local inflammation in experimental Th1- and Th2-type immune response. | Bulletin of experimental biology and medicine 20120801 |
Characterization of patients with arthritis referred for gold therapy in the era of biologics. | The Journal of rheumatology 20120401 |
Bone marrow gold. | British journal of haematology 20120101 |
[Treatment of rheumatic diseases: current status and future prospective. Topics: II. Immunosuppressant/antirheumatic drugs; 6. Bucillamine and gold (gold sodium thiomalate and auranofin)]. | Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine 20111010 |
[Against parenteral gold therapy in rheumatoid arthritis]. | Deutsche medizinische Wochenschrift (1946) 20110801 |
Aurothiomalate as preventive and chain-breaking antioxidant in radical degradation of high-molar-mass hyaluronan. | Chemistry & biodiversity 20110701 |
Study of anti-inflammatory action of aurothiomalate, an inhibitor of NF-κB. | Bulletin of experimental biology and medicine 20110601 |
Gold sodium thiomalate for the treatment of rheumatoid arthritis in a patient with hepatitis B. | The Annals of pharmacotherapy 20110401 |
Synthesis and characterization of gold at gold(i)-thiomalate core at shell nanoparticles. | ACS nano 20100622 |
Aurothiomalate inhibits cyclooxygenase 2, matrix metalloproteinase 3, and interleukin-6 expression in chondrocytes by increasing MAPK phosphatase 1 expression and decreasing p38 phosphorylation: MAPK phosphatase 1 as a novel target for antirheumatic drugs. | Arthritis and rheumatism 20100601 |
Successful treatment of juvenile pemphigus foliaceus in a Nigerian Dwarf goat. | Journal of the American Veterinary Medical Association 20100315 |
Corneal chrysiasis: in vivo confocal microscopy analysis. | European journal of ophthalmology 20100101 |
Immunomodulatory drugs regulate HMGB1 release from activated human monocytes. | Molecular medicine (Cambridge, Mass.) 20100101 |
Beneficial effect of aurothiomalate on murine malaria. | Malaria journal 20100101 |
Atypical protein kinase C{iota} is required for bronchioalveolar stem cell expansion and lung tumorigenesis. | Cancer research 20091001 |
In vitro distribution of gold in serum proteins after incubation of sodium aurothiomalate and auranofin with human blood and its pharmacological significance. | Biological trace element research 20090901 |
Investigation of contact allergy to dental metals in 206 patients. | Contact dermatitis 20090601 |
Gold- and silver-induced murine autoimmunity--requirement for cytokines and CD28 in murine heavy metal-induced autoimmunity. | Clinical and experimental immunology 20090301 |
[Effect of disease modifying anti-rheumatic drugs on radiographic progression in rheumatoid arthritis]. | Clinical calcium 20090301 |
Pro-apoptotic effect of aurothiomalate in prostate cancer cells. | Cell cycle (Georgetown, Tex.) 20090115 |
Antirheumatic drug response signatures in human chondrocytes: potential molecular targets to stimulate cartilage regeneration. | Arthritis research & therapy 20090101 |
Disability measured by the modified health assessment questionnaire in early rheumatoid arthritis: prognostic factors after two years of follow-up. | Clinical and experimental rheumatology 20090101 |
Promiscuous interaction between gold-specific T cells and APCs in gold allergy. | Journal of immunology (Baltimore, Md. : 1950) 20081201 |
The thioredoxin system mediates redox-induced cell death in human colon cancer cells: implications for the mechanism of action of anticancer agents. | Cancer research 20081015 |
[Antirheumatic agents for treatment of rheumatoid arthritis]. | Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine 20081010 |
Atypical protein kinase C iota expression and aurothiomalate sensitivity in human lung cancer cells. | Cancer research 20080715 |
Aurothiomalate inhibits COX-2 expression in chondrocytes and in human cartilage possibly through its effects on COX-2 mRNA stability. | European journal of pharmacology 20080610 |
Aurocyanide, dicyano-aurate (I), a pharmacologically active metabolite of medicinal gold complexes. | Inflammopharmacology 20080601 |
Gold stimulates Ca2+ entry into and subsequent suicidal death of erythrocytes. | Toxicology 20080227 |
Mechanism of action of the disease-modifying anti-arthritic thiol agents D-penicillamine and sodium aurothiomalate: restoration of cellular free thiols and sequestration of reactive aldehydes. | European journal of pharmacology 20080202 |
Pivotal advance: inhibition of HMGB1 nuclear translocation as a mechanism for the anti-rheumatic effects of gold sodium thiomalate. | Journal of leukocyte biology 20080101 |
All that glitters may be HMGB1: an interview with Dr. Ulf Andersson. | Journal of leukocyte biology 20080101 |
Erythrocyte membrane gold levels after treatment with auranofin and sodium aurothiomalate. | Biological trace element research 20080101 |
Gold causes genetically determined autoimmune and immunostimulatory responses in mice. | Clinical and experimental immunology 20071001 |
Gold therapy in women planning pregnancy: outcomes in one center. | The Journal of rheumatology 20070901 |
Protein kinase C iota: human oncogene, prognostic marker and therapeutic target. | Pharmacological research 20070601 |
Paraquat increases cyanide-insensitive respiration in murine lung epithelial cells by activating an NAD(P)H:paraquat oxidoreductase: identification of the enzyme as thioredoxin reductase. | The Journal of biological chemistry 20070316 |
Effects of disease-modifying anti-rheumatic drugs (DMARDs) on the activities of rheumatoid arthritis-associated cathepsins K and S. | Biological chemistry 20070301 |
[Gold. Effective therapy for mucosal lesions of pemphigus vulgaris]. | Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete 20070201 |
The anti-rheumatic gold salt aurothiomalate suppresses interleukin-1beta-induced hyaluronan accumulation by blocking HAS1 transcription and by acting as a COX-2 transcriptional repressor. | The Journal of biological chemistry 20070126 |
DNA hybridization sensor based on aurothiomalate electroactive label on glassy carbon electrodes. | Biosensors & bioelectronics 20070115 |
Prognostic markers of clinical remission in early rheumatoid arthritis after two years of DMARDs in a clinical setting. | Clinical and experimental rheumatology 20070101 |
Aurothiomalate inhibits transformed growth by targeting the PB1 domain of protein kinase Ciota. | The Journal of biological chemistry 20060922 |
Sublethal concentrations of diverse gold compounds inhibit mammalian cytosolic thioredoxin reductase (TrxR1). | Toxicology in vitro : an international journal published in association with BIBRA 20060901 |
Gold-induced reactive oxygen species (ROS) do not mediate suppression of monocytic mitochondrial or secretory function. | Toxicology in vitro : an international journal published in association with BIBRA 20060801 |
Interferon-gamma secreted from peripheral blood mononuclear cells as a possible diagnostic marker for allergic contact dermatitis to gold. | Contact dermatitis 20060801 |
Noble metals strip peptides from class II MHC proteins. | Nature chemical biology 20060401 |
Laser induced chrysiasis: disfiguring hyperpigmentation following Q-switched laser therapy in a woman previously treated with gold. | The Journal of rheumatology 20060301 |
Determination of human serum albumin using aurothiomalate as electroactive label. | Analytical and bioanalytical chemistry 20060201 |
A novel small-molecule inhibitor of protein kinase Ciota blocks transformed growth of non-small-cell lung cancer cells. | Cancer research 20060201 |
Gold nanocluster formation using metallothionein: mass spectrometry and electron microscopy. | Journal of molecular biology 20060113 |
Gold, nitritoid reactions and angiotensin-converting enzyme inhibitors. | Rheumatology (Oxford, England) 20060101 |
Mechanisms of aurothiomalate-Cys2His2 zinc finger interactions. | Chemical research in toxicology 20051201 |
An editorial is a golden opportunity. | The Journal of rheumatology 20050601 |
Parenteral gold preparations. Efficacy and safety of therapy after switching from aurothioglucose to aurothiomalate. | The Journal of rheumatology 20050601 |
[Pemphigus foliaceus in a Haflinger gelding]. | Schweizer Archiv fur Tierheilkunde 20050501 |
Anti-rheumatic gold compounds as sublethal modulators of monocytic LPS-induced cytokine secretion. | Toxicology in vitro : an international journal published in association with BIBRA 20050401 |
Caspase-independent retinal ganglion cell death after target ablation in the neonatal rat. | The European journal of neuroscience 20050101 |
The ability of disease modifying antirheumatic drugs to induce and maintain improvement in patients with rheumatoid arthritis. epidemiology of DMARDs treatment in Japan. | Clinical and experimental rheumatology 20050101 |
[Disease modifying anti-rheumatic drugs (DMARDs): an overview]. | Nihon rinsho. Japanese journal of clinical medicine 20050101 |
[Adverse effects of DMARDs in treatment of rheumatoid arthritis]. | Nihon rinsho. Japanese journal of clinical medicine 20050101 |
Aurothiomalate and hydroxychloroquine inhibit nitric oxide production in chondrocytes and in human osteoarthritic cartilage. | Scandinavian journal of rheumatology 20050101 |
Effect of metal complexes on thioredoxin reductase and the regulation of mitochondrial permeability conditions. | Annals of the New York Academy of Sciences 20041201 |
Inhibition of lysosomal cysteine proteases by chrysotherapeutic compounds: a possible mechanism for the antiarthritic activity of Au(I). | Bioorganic & medicinal chemistry letters 20041018 |
Gold complexes inhibit mitochondrial thioredoxin reductase: consequences on mitochondrial functions. | Journal of inorganic biochemistry 20041001 |
Can gold therapy be used more safely in rheumatoid arthritis? Adverse drug reactions are more likely in patients with nodular disease, independent of HLA-DR3 status. | The Journal of rheumatology 20041001 |
Effects of antirheumatic gold compounds on the conversion of xanthine dehydrogenase to oxidase in rabbit liver cytosol in vitro. | Life sciences 20040723 |
Gold sodium thiomalate improves membrane potential impaired by high-frequency stimulation. | Canadian journal of physiology and pharmacology 20040401 |
Overexpression of thioredoxin reductase 1 regulates NF-kappa B activation. | Journal of cellular physiology 20040101 |
Chemical and biological considerations in the treatment of metal intoxications by chelating agents. | Mini reviews in medicinal chemistry 20040101 |
Skin reaction associated with chrysotherapy: an unusual case. | Clinical and experimental rheumatology 20040101 |
Psoriatic arthritis. | Dermatologic therapy 20040101 |
Clinical and radiological disease-course in a Swedish DMARD-treated early RA-inception cohort: an observational study. | Scandinavian journal of rheumatology 20040101 |
Hyaluronidase inhibitors (sodium cromoglycate and sodium auro-thiomalate) reduce the local tissue damage and prolong the survival time of mice injected with Naja kaouthia and Calloselasma rhodostoma venoms. | Toxicon : official journal of the International Society on Toxinology 20031101 |
Gold sodium thiomalate and chloroquine inhibit cytokine production in monocytic THP-1 cells through distinct transcriptional and posttranslational mechanisms. | Journal of clinical immunology 20031101 |
Confocal microscopy in ocular chrysiasis. | Cornea 20030801 |
Evidence for immunostimulatory effects of intramuscular gold in patients with rheumatoid arthritis: correlation with skin reactions. | The Journal of rheumatology 20030801 |
Fatal, gold-induced pneumonitis. | Rheumatology international 20030701 |
Termination of disease-modifying antirheumatic drugs in rheumatoid arthritis and in psoriatic arthritis. A comparative study of 270 cases. | Zeitschrift fur Rheumatologie 20030401 |
Inhibition of TPA-induced NF-kappaB nuclear translocation and production of NO and PGE2 by the anti-rheumatic gold compounds. | The Journal of pharmacy and pharmacology 20030201 |
[Gold preparations in therapy of rheumatoid and psoriatic arthritis]. | Terapevticheskii arkhiv 20030101 |
[Analysis of efficacy and safety of multiple intravenous infusion of anti-tumor necrosis factor-alpha monoclonal antibody (Remicade) combined with methotrexate compared with sodium aurothiomalate and intramuscular depot methylprednisolone in rheumatoid arthritis]. | Polskie Archiwum Medycyny Wewnetrznej 20021101 |
Gold sodium thiomalate (GSTM) inhibits lipopolysaccharide stimulated tumor necrosis factor-alpha through ceramide pathway. | Cellular immunology 20020901 |
Long term efficacy and safety of cyclosporin versus parenteral gold in early rheumatoid arthritis: a three year study of radiographic progression, renal function, and arterial hypertension. | Annals of the rheumatic diseases 20020601 |
Rheumatoid arthritis: limiting the damage. | Nursing times 20020301 |
Radiographic outcome after three years of patients with early erosive rheumatoid arthritis treated with intramuscular methotrexate or parenteral gold. Extension of a one-year double-blind study in 174 patients. | Rheumatology (Oxford, England) 20020201 |
Effects of gold on cytokine production in vitro; increase of monocyte dependent interleukin 10 production and decrease of interferon-gamma levels. | The Journal of rheumatology 20020101 |
Rheumatoid arthritis, gold therapy, contact allergy and blood cytokines. | BMC dermatology 20020101 |
[Vasomotor (nitritoid) reactions induced by sodium aurothiomalate and enap]. | Terapevticheskii arkhiv 20020101 |
Gold sodium thiomalate suppresses the differentiation and function of human dendritic cells from peripheral blood monocytes. | Clinical and experimental rheumatology 20020101 |
Gold induced interstitial keratitis. | The British journal of ophthalmology 20011101 |
Nitritoid reactions: case reports, review, and recommendations for management. | The Journal of rheumatology 20011001 |
Lymphadenopathy and lymph node infarction as a result of gold injections. | Journal of clinical pathology 20010701 |
Comparative study of intramuscular gold and methotrexate in a rheumatoid arthritis population from a socially deprived area. | Annals of the rheumatic diseases 20010601 |
Mechanism of action of disease modifying anti-rheumatic agent, gold sodium thiomalate (GSTM). | International immunopharmacology 20010601 |
[Low dose steroid therapy in rheumatoid arthritis: a model for therapy of inflammatory diseases?--Results of the LDPT Study]. | Zeitschrift fur Rheumatologie 20010401 |
Subcorneal pustular dermatosis-type IgA pemphigus induced by thiol drugs. | European journal of dermatology : EJD 20010101 |
Immunomodulatory effect of gold sodium thiomalate on murine acquired immunodeficiency syndrome. | Microbiology and immunology 20010101 |
Cutaneous drug reaction case reports: from the world literature. | American journal of clinical dermatology 20010101 |
Inhibitors of caspase homologues suppress an apoptotic phenotype in cultured rabbit corpora lutea. | Reproduction, fertility, and development 20010101 |
Specific inhibition of rRNA transcription and dynamic relocation of fibrillarin induced by mercury. | Experimental cell research 20000825 |
Thiol-reactive metal compounds inhibit NF-kappa B activation by blocking I kappa B kinase. | Journal of immunology (Baltimore, Md. : 1950) 20000601 |
N-acetyl-beta-D-glucosaminidase urinary excretion as an early indicator of kidney damage in rheumatoid arthritis patients starting on parenteral gold and Depo-Medrone/placebo injections. | Clinical rheumatology 19990101 |
A long-term five-year randomized controlled trial of hydroxychloroquine, sodium aurothiomalate, auranofin and penicillamine in the treatment of patients with rheumatoid arthritis. | British journal of rheumatology 19980901 |
Aurothiolates inhibit HIV-1 infectivity by gold(I) ligand exchange with a component of the virion surface. | Virology 19930201 |
[Gold-induced severe cholestatic jaundice in rheumatoid arthritis patient and effect of repeated steroid pulse therapy]. | Ryumachi. [Rheumatism] 19921001 |
The natural course of gold and penicillamine nephropathy: a longterm study of 54 patients. | Advances in experimental medicine and biology 19890101 |
Effects of long-term aurothiomalate and D-penicillamine treatments on renal function and urinary excretion of prostanoids in patients with rheumatoid arthritis. | International journal of clinical pharmacology research 19880101 |
Hematuria in patients with rheumatoid arthritis receiving gold and D-penicillamine. | The Journal of rheumatology 19870201 |
Renal changes in patients with rheumatoid arthritis treated with sodium thiomalate and D-penicillamine. | Acta medica Iugoslavica 19870101 |
Mercuric chloride-, gold sodium thiomalate-, and D-penicillamine-induced antinuclear antibodies in mice. | Toxicology and applied pharmacology 19861101 |
HLA-A,-B, and -DR antigens in relation to gold and D-penicillamine toxicity in Greek patients with RA. | Disease markers 19860601 |
Long-term efficacy and safety of auranofin: a review of clinical experience. | Scandinavian journal of rheumatology. Supplement 19860101 |
HLA antigens and adverse drug reactions to sodium aurothiomalate and D-penicillamine in patients with rheumatoid arthritis. | Clinical rheumatology 19850301 |
Proteinuria in gold-treated rheumatoid arthritis. | Annals of internal medicine 19840801 |
Penicillamine induced myasthenia reactivated by gold. | British medical journal (Clinical research ed.) 19840121 |
[Multicenter double-blind comparison of auranofin and Tauredon]. | Wiener klinische Wochenschrift. Supplementum 19840101 |
Prior gold therapy does not influence the adverse effects of D-penicillamine in rheumatoid arthritis. | Arthritis and rheumatism 19820801 |
Proteinuria in rheumatoid arthritis--drug-induced or amyloid? | Annals of the rheumatic diseases 19810601 |
[Is myositis in chronic polyarthritis using d-penicillamine drug-induced?]. | Schweizerische medizinische Wochenschrift 19810103 |
HLA-DR antigens and toxic reaction to sodium aurothiomalate and D-penicillamine in patients with rheumatoid arthritis. | The New England journal of medicine 19800807 |
Adverse reactions to D-penicillamine after gold toxicity. | British medical journal 19800621 |
The subacute and chronic toxicity of SK&F 36914, SK&F D-39162 and gold sodium thiomalate in rats. | Veterinary pathology 19780801 |
Precipitating autoantibody to a ubiquitous tissue antigen: association with rheumatoid arthritis treated with sodium aurothiomalate or d-penicillamine. | Clinical immunology and immunopathology 19780701 |
Gold nephropathy. Ultrastructural, fluorescence, and microanalytic studies of two patients. | Archives of pathology & laboratory medicine 19761201 |
Comparative toxicity of gold preparations in treatment of rheumatoid arthritis. | Annals of the rheumatic diseases 19760401 |
Trial comparing D-penicillamine and gold in rheumatoid arthritis. Preliminary report. | Annals of the rheumatic diseases 19741101 |
Mefanamic acid-induced haemolytic anaemia. | British medical journal 19700502 |
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