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12244-57-4

12244-57-4 | Butanedioic acid, 2-mercapto-, gold(1+) sodium salt (1:1:?)

CAS No: 12244-57-4 Catalog No: AG001790 MDL No:

Product Description

Catalog Number:
AG001790
Chemical Name:
Butanedioic acid, 2-mercapto-, gold(1+) sodium salt (1:1:?)
CAS Number:
12244-57-4
IUPAC Name:
disodium;gold(1+);2-sulfidobutanedioate
InChI:
InChI=1S/C4H6O4S.Au.2Na/c5-3(6)1-2(9)4(7)8;;;/h2,9H,1H2,(H,5,6)(H,7,8);;;/q;3*+1/p-3
InChI Key:
VXIHRIQNJCRFQX-UHFFFAOYSA-K
EC Number:
235-479-7

Properties

Complexity:
126  
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
4  
Defined Atom Stereocenter Count:
0
Defined Bond Stereocenter Count:
0
Exact Mass:
389.921g/mol
Formal Charge:
0
Heavy Atom Count:
12  
Hydrogen Bond Acceptor Count:
5  
Hydrogen Bond Donor Count:
0
Isotope Atom Count:
0
Molecular Weight:
390.07g/mol
Monoisotopic Mass:
389.921g/mol
Rotatable Bond Count:
1  
Topological Polar Surface Area:
81.3A^2
Undefined Atom Stereocenter Count:
1  
Undefined Bond Stereocenter Count:
0

Literature

Title Journal
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Bone marrow gold. British journal of haematology 20120101
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Gold sodium thiomalate for the treatment of rheumatoid arthritis in a patient with hepatitis B. The Annals of pharmacotherapy 20110401
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Aurothiomalate inhibits cyclooxygenase 2, matrix metalloproteinase 3, and interleukin-6 expression in chondrocytes by increasing MAPK phosphatase 1 expression and decreasing p38 phosphorylation: MAPK phosphatase 1 as a novel target for antirheumatic drugs. Arthritis and rheumatism 20100601
Successful treatment of juvenile pemphigus foliaceus in a Nigerian Dwarf goat. Journal of the American Veterinary Medical Association 20100315
Corneal chrysiasis: in vivo confocal microscopy analysis. European journal of ophthalmology 20100101
Immunomodulatory drugs regulate HMGB1 release from activated human monocytes. Molecular medicine (Cambridge, Mass.) 20100101
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Promiscuous interaction between gold-specific T cells and APCs in gold allergy. Journal of immunology (Baltimore, Md. : 1950) 20081201
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Pivotal advance: inhibition of HMGB1 nuclear translocation as a mechanism for the anti-rheumatic effects of gold sodium thiomalate. Journal of leukocyte biology 20080101
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DNA hybridization sensor based on aurothiomalate electroactive label on glassy carbon electrodes. Biosensors & bioelectronics 20070115
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Noble metals strip peptides from class II MHC proteins. Nature chemical biology 20060401
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Gold complexes inhibit mitochondrial thioredoxin reductase: consequences on mitochondrial functions. Journal of inorganic biochemistry 20041001
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Fatal, gold-induced pneumonitis. Rheumatology international 20030701
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