CAS 1200-22-2 | 1,2-Dithiolane-3-pentanoic acid, (3R)- | CAS Number 1200-22-2

Title	Journal
α-Lipoic acid inhibits testicular and epididymal oxidative damage and improves fertility efficacy in arsenic-intoxicated rats.	Journal of biochemical and molecular toxicology 20180201
Cytoprotection of lipoic acid against toxicity induced by saxitoxin in hippocampal cell line HT-22 through in silico modeling and in vitro assays.	Toxicology 20180115
Biocorona formation on gold nanoparticles modulates human proximal tubule kidney cell uptake, cytotoxicity and gene expression.	Toxicology in vitro : an international journal published in association with BIBRA 20170801
Lipoic acid and Calligonum comosumon attenuate aroclor 1260-induced testicular toxicity in adult rats.	Environmental toxicology 20170401
Zinc deficiency affects the STAT1/3 signaling pathways in part through redox-mediated mechanisms.	Redox biology 20170401
Alpha-lipoic acid reduces methylmercury-induced neuronal injury in rat cerebral cortex via antioxidation pathways.	Environmental toxicology 20170301
α-Lipoic acid potentially targets AMP-activated protein kinase and energy production in the fetal brain to ameliorate dioxin-produced attenuation in fetal steroidogenesis.	The Journal of toxicological sciences 20170101
Role of Cyt-C/caspases-9,3, Bax/Bcl-2 and the FAS death receptor pathway in apoptosis induced by zinc oxide nanoparticles in human aortic endothelial cells and the protective effect by alpha-lipoic acid.	Chemico-biological interactions 20161025
Cardioprotective effects of lipoic acid, quercetin and resveratrol on oxidative stress related to thyroid hormone alterations in long-term obesity.	The Journal of nutritional biochemistry 20160701
Alpha lipoic acid supplementation attenuates reactive oxygen species in hypothalamic paraventricular nucleus and sympathoexcitation in high salt-induced hypertension.	Toxicology letters 20160122
Co-administration of α-lipoic acid and cyclosporine aggravates colon ulceration of acetic acid-induced ulcerative colitis via facilitation of NO/COX-2/miR-210 cascade.	Toxicology and applied pharmacology 20151101
Alpha-lipoic acid protects against cadmium-induced hepatotoxicity via calcium signalling and gap junctional intercellular communication in rat hepatocytes.	The Journal of toxicological sciences 20150801
α-Lipoic acid (α-LA) inhibits the transcriptional activity of interferon regulatory factor 1 (IRF-1) via SUMOylation.	Toxicology in vitro : an international journal published in association with BIBRA 20141001
Modulatory effects of curcumin, silybin-phytosome and alpha-R-lipoic acid against thioacetamide-induced liver cirrhosis in rats.	Chemico-biological interactions 20140605
α-Lipoic acid protects mitochondrial enzymes and attenuates lipopolysaccharide-induced hypothermia in mice.	Free radical biology & medicine 20140601
Arsenic trioxide induces unfolded protein response in vascular endothelial cells.	Archives of toxicology 20140201
Lipoamide channel-binding sulfonamides selectively inhibit mycobacterial lipoamide dehydrogenase.	Biochemistry 20131223
Lipoic acid mitigates bisphenol A-induced testicular mitochondrial toxicity in rats.	Toxicology and industrial health 20131101
Lipoic acid protects C6 cells against ammonia exposure through Na⁺-K⁺-Cl⁻ co-transporter and PKC pathway.	Toxicology in vitro : an international journal published in association with BIBRA 20131001
Inhibitory effect of α-lipoic acid on thioacetamide-induced tumor promotion through suppression of inflammatory cell responses in a two-stage hepatocarcinogenesis model in rats.	Chemico-biological interactions 20130925
Lipoic acid prevents Cr(6+) induced cell transformation and the associated genomic dysregulation.	Environmental toxicology and pharmacology 20130701
α-Lipoic acid protects against arsenic trioxide-induced acute QT prolongation in anesthetized guinea pigs.	European journal of pharmacology 20130405
Effects of lipoic acid on AMPK and adiponectin in adipose tissue of low- and high-fat-fed rats.	European journal of nutrition 20130301
Impact of dihydrolipoic acid on mouse embryonic stem cells and related regulatory mechanisms.	Environmental toxicology 20130201
Cytoprotective effect of alpha-lipoic acid on paraquat-exposed human bronchial epithelial cells via activation of nuclear factor erythroid related factor-2 pathway.	Biological & pharmaceutical bulletin 20130101
Interaction of 9,10-phenanthraquinone with dithiol causes oxidative modification of Cu,Zn-superoxide dismutase (SOD) through redox cycling.	The Journal of toxicological sciences 20130101
Lipoic acid administration prevents nonalcoholic steatosis linked to long-term high-fat feeding by modulating mitochondrial function.	The Journal of nutritional biochemistry 20121201
Functional and molecular aspects of biotin uptake via SMVT in human corneal epithelial (HCEC) and retinal pigment epithelial (D407) cells.	The AAPS journal 20121201
Impact of gold nanoparticle coating on redox homeostasis.	International journal of pharmaceutics 20121115
Neuroprotection of lipoic acid treatment promotes angiogenesis and reduces the glial scar formation after brain injury.	Neuroscience 20121108
α-lipoic acid prevents non-alcoholic fatty liver disease in OLETF rats.	Liver international : official journal of the International Association for the Study of the Liver 20121101
Effects of lipoic acid on lipolysis in 3T3-L1 adipocytes.	Journal of lipid research 20121101
Zinc and multi-mineral supplementation should mitigate the pathogenic impact of cadmium exposure.	Medical hypotheses 20121101
Alpha-lipoic acid induces sodium iodide symporter expression in TPC-1 thyroid cancer cell line.	Nuclear medicine and biology 20121101
Alpha-lipoic acid pre- and post-treatments provide protection against in vitro ischemia-reperfusion injury in cerebral endothelial cells via Akt/mTOR signaling.	Brain research 20121030
Preparation, characterization and efficacy evaluation of synthetic biocompatible polymers linking natural antioxidants.	Molecules (Basel, Switzerland) 20121026
Growth of in situ functionalized luminescent silver nanoclusters by direct reduction and size focusing.	ACS nano 20121023
Molecular expression and functional activity of sodium dependent multivitamin transporter in human prostate cancer cells.	International journal of pharmaceutics 20121015
Alpha-lipoic acid induces adipose triglyceride lipase expression and decreases intracellular lipid accumulation in HepG2 cells.	European journal of pharmacology 20121005
Photoinduced phase transfer of luminescent quantum dots to polar and aqueous media.	Journal of the American Chemical Society 20121003
Determination of lipoic acid, Trolox methyl ether and tocopherols in human plasma by liquid-chromatography and ion-trap tandem mass spectrometry.	Biomedical chromatography : BMC 20121001
Lipoic acid improves mitochondrial function in nonalcoholic steatosis through the stimulation of sirtuin 1 and sirtuin 3.	Obesity (Silver Spring, Md.) 20121001
Supplementation with antioxidants attenuates transient worsening of retinopathy in diabetes caused by acute intensive insulin therapy.	Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie 20121001
The protective effect of alpha lipoic acid on Schwann cells exposed to constant or intermittent high glucose.	Biochemical pharmacology 20121001
Protective effects of a novel synthetic α-lipoic acid-decursinol hybrid compound in experimentally induced transient cerebral ischemia.	Cellular and molecular neurobiology 20121001
α-Lipoic acid ameliorates impaired glucose uptake in LYRM1 overexpressing 3T3-L1 adipocytes through the IRS-1/Akt signaling pathway.	Journal of bioenergetics and biomembranes 20121001
A systematic review and meta-analysis of α-lipoic acid in the treatment of diabetic peripheral neuropathy.	European journal of endocrinology 20121001
Dietary supplementation with N-acetyl cysteine, α-tocopherol and α-lipoic acid reduces the extent of oxidative stress and proinflammatory state in aged rat brain.	Biogerontology 20121001
Sodium butyrate potentiates carbon tetrachloride-induced acute liver injury in mice.	Toxicology mechanisms and methods 20121001
Xenobiotics and autoimmunity: does acetaminophen cause primary biliary cirrhosis?	Trends in molecular medicine 20121001
Studies on synthesis and activation mechanism of mitomycin dimers connected by 1,2-dithiolane and diol linkers.	Bioorganic & medicinal chemistry 20121001
Chemerin and apelin are positively correlated with inflammation in obese type 2 diabetic patients.	Chinese medical journal 20121001
Neuroprotective effect of alpha-lipoic acid on hydrostatic pressure-induced damage of retinal ganglion cells in vitro.	Neuroscience letters 20120920
Chemiluminescence detection of amino acids and related compounds using acidic potassium permanganate, manganese(IV) or tris(2,2'-bipyridine)ruthenium(III).	Talanta 20120915
Modulatory effects of vitamin E, acetyl-L-carnitine and α-lipoic acid on new potential biomarkers for Alzheimer's disease in rat model.	Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie 20120901
Diffuse reflectance spectroscopy of fibrous proteins.	Amino acids 20120901
Bioactive compounds with effects on inflammation markers in humans.	International journal of food sciences and nutrition 20120901
Oxidative stress underlying axonal degeneration in adrenoleukodystrophy: a paradigm for multifactorial neurodegenerative diseases?	Biochimica et biophysica acta 20120901
Maternal antioxidants prevent β-cell apoptosis and promote formation of dual hormone-expressing endocrine cells in male offspring following fetal and neonatal nicotine exposure.	Journal of diabetes 20120901
Polychlorinated biphenyl quinone metabolites lead to oxidative stress in HepG2 cells and the protective role of dihydrolipoic acid.	Toxicology in vitro : an international journal published in association with BIBRA 20120901
Age and gender dependent bioavailability of R- and R,S-α-lipoic acid: a pilot study.	Pharmacological research 20120901
Targeting mitochondrial oxidative stress through lipoic acid synthase: a novel strategy to manage diabetic cardiovascular disease.	Cardiovascular & hematological agents in medicinal chemistry 20120901
Vascular function and the role of oxidative stress in heart failure, heart transplant, and beyond.	Hypertension (Dallas, Tex. : 1979) 20120901
Recent patents and developments in glaucoma biomarkers.	Recent patents on endocrine, metabolic & immune drug discovery 20120901
Reduction-responsive disassemblable core-cross-linked micelles based on poly(ethylene glycol)-b-poly(N-2-hydroxypropyl methacrylamide)-lipoic acid conjugates for triggered intracellular anticancer drug release.	Biomacromolecules 20120813
Screening of well-established drugs targeting cancer metabolism: reproducibility of the efficacy of a highly effective drug combination in mice.	Investigational new drugs 20120801
Therapeutic effect of alpha lipoic acid combined with praziquantel on liver fibrosis induced by Schistosoma mansoni challenged mice.	Parasitology research 20120801
Lipoic acid metabolism of Plasmodium--a suitable drug target.	Current pharmaceutical design 20120801
High-fat diets impair spatial learning of mice in the Y-maze paradigm: ameliorative potential of α-lipoic acid.	Journal of medicinal food 20120801
Retraction. Alpha-lipoic acid supplementation and diabetes.	Nutrition reviews 20120801
Pain Management in patients with diabetic nephropathy: the emerging role of α-lipoic acid.	Foot & ankle specialist 20120801
Direct enantioseparation of lipoic acid in dietary supplements by capillary electrophoresis using trimethyl-β-cyclodextrin as a chiral selector.	Electrophoresis 20120801
Microwave-assisted rapid synthesis of luminescent gold nanoclusters for sensing Hg2+ in living cells using fluorescence imaging.	Nanoscale 20120721
Syntheses and characterization of lisinopril-coated gold nanoparticles as highly stable targeted CT contrast agents in cardiovascular diseases.	Langmuir : the ACS journal of surfaces and colloids 20120717
Coenzyme Q10 deficiency in patients with Parkinson's disease.	Journal of the neurological sciences 20120715
Determination of lipoic acid by flow-injection and high-performance liquid chromatography with chemiluminescence detection.	Talanta 20120715
Combination pharmacotherapy for the treatment of neuropathic pain in adults.	The Cochrane database of systematic reviews 20120711
Identification and functional expression of the mitochondrial pyruvate carrier.	Science (New York, N.Y.) 20120706
Evaluation of the antioxidative capability of commonly used antioxidants in dermocosmetics by in vivo detection of protein carbonylation in human stratum corneum.	Journal of photochemistry and photobiology. B, Biology 20120702
GLUT1 deficiency syndrome in clinical practice.	Epilepsy research 20120701
The effects of gold nanoparticles in wound healing with antioxidant epigallocatechin gallate and α-lipoic acid.	Nanomedicine : nanotechnology, biology, and medicine 20120701
Quantum-chemical investigation of the structure and the antioxidant properties of α-lipoic acid and its metabolites.	Journal of molecular modeling 20120701
Antioxidants for Alzheimer disease: a randomized clinical trial with cerebrospinal fluid biomarker measures.	Archives of neurology 20120701
Regulation of inducible heme oxygenase and cyclooxygenase isozymes in a mouse model of spotted fever group rickettsiosis.	Microbial pathogenesis 20120701
Alfa-lipoic acid protects testosterone secretion pathway and sperm quality against 4-tert-octylphenol induced reproductive toxicity.	Ecotoxicology and environmental safety 20120701
Development of a simple and high-throughput method for detecting aflatoxins production in culture media.	Letters in applied microbiology 20120701
Alpha-lipoic acid reduces peridural fibrosis after laminectomy of lumbar vertebrae in rabbits.	Acta neurochirurgica 20120701
Reduced alpha-lipoic acid synthase gene expression exacerbates atherosclerosis in diabetic apolipoprotein E-deficient mice.	Atherosclerosis 20120701
Antioxidants and endothelial dysfunction in young and elderly people: is flow-mediated dilation useful to assess acute effects?	Hypertension (Dallas, Tex. : 1979) 20120701
A cost effective complement to managing the vitamin D deficient and anemic dialysis patient in the bundled world.	Nephrology news & issues 20120701
Effects of exercise and antioxidant supplementation on endothelial gene expression.	International journal of cardiology 20120628
Involvement of glutamate, oxidative stress and inducible nitric oxide synthase in the convulsant activity of ciprofloxacin in mice.	European journal of pharmacology 20120615
Lipoic acid prevents steroid-induced osteonecrosis in rabbits.	Rheumatology international 20120601
Effects of α-lipoic acid, vitamins E and C upon the heat stress in Japanese quails.	Journal of animal physiology and animal nutrition 20120601
The impact of lipoic acid on endothelial function and proteinuria in quinapril-treated diabetic patients with stage I hypertension: results from the QUALITY study.	Journal of cardiovascular pharmacology and therapeutics 20120601
α-Lipoic acid prevents mild portal endotoxaemia-induced hepatic inflammation and β cell dysfunction.	European journal of clinical investigation 20120601
Alpha-lipoic acid attenuates atherosclerotic lesions and inhibits proliferation of vascular smooth muscle cells through targeting of the Ras/MEK/ERK signaling pathway.	Molecular biology reports 20120601
New advances in the in-vitro culture of Dientamoeba fragilis.	Parasitology 20120601
Sodium dependent multivitamin transporter (SMVT): a potential target for drug delivery.	Current drug targets 20120601
Improvement of myocardial lipid accumulation and prevention of PGC-1α induction by fenofibrate.	Molecular medicine reports 20120601
α-Lipoic acid regulates lipid metabolism through induction of sirtuin 1 (SIRT1) and activation of AMP-activated protein kinase.	Diabetologia 20120601
Arsenic modulates heme oxygenase-1, interleukin-6, and vascular endothelial growth factor expression in endothelial cells: roles of ROS, NF-κB, and MAPK pathways.	Archives of toxicology 20120601
The role of natural killer (NK) and NK T cells in the loss of tolerance in murine primary biliary cirrhosis.	Clinical and experimental immunology 20120601
Cap-independent Nrf2 translation is part of a lipoic acid-stimulated detoxification stress response.	Biochimica et biophysica acta 20120601
The influence of EDDS on the metabolic and transcriptional responses induced by copper in hydroponically grown Brassica carinata seedlings.	Plant physiology and biochemistry : PPB 20120601
α-Lipoic acid protects 3T3-L1 adipocytes from NYGGF4 (PID1) overexpression-induced insulin resistance through increasing phosphorylation of IRS-1 and Akt.	Journal of bioenergetics and biomembranes 20120601
Evidence for using alpha-lipoic acid in reducing lipoprotein and inflammatory related atherosclerotic risk.	Journal of dietary supplements 20120601
α-lipoic acid inhibits high glucose-induced apoptosis in HIT-T15 cells.	Development, growth & differentiation 20120601
α-Lipoic acid reduced weight gain and improved the lipid profile in rats fed with high fat diet.	Nutrition research and practice 20120601
Ameliorating effect of DL-α-lipoic acid against cisplatin-induced nephrotoxicity and cardiotoxicity in experimental animals.	Drug discoveries & therapeutics 20120601
New α-lipoic acid derivative, DHL-HisZn, ameliorates renal ischemia-reperfusion injury in rats.	The Journal of surgical research 20120515
Biosynthetically intriguing chlorinated lipophilic metabolites from geographically distant tropical marine cyanobacteria.	The Journal of organic chemistry 20120504
Effect of α-lipoic acid on sperm quality, reproductive tract measures in thinner exposed rats.	Andrologia 20120501
Antioxidant-enriched diet does not delay the progression of age-related hearing loss.	Neurobiology of aging 20120501
ROS constitute a convergence nexus in the development of IGF1 resistance and impaired wound healing in a rat model of type 2 diabetes.	Disease models & mechanisms 20120501
Alpha lipoic acid selectively inhibits proliferation and adhesion to fibronectin of v-H-ras-transformed 3Y1 cells.	Journal of clinical biochemistry and nutrition 20120501
Nootropic activity of acetaminophen against colchicine induced cognitive impairment in rats.	Journal of clinical biochemistry and nutrition 20120501
Italian guidelines for primary headaches: 2012 revised version.	The journal of headache and pain 20120501
[Experience of diagnosis and treatment of phlegmon in the diabetic foot syndrome].	Klinichna khirurhiia 20120501
Treatment for mitochondrial disorders.	The Cochrane database of systematic reviews 20120418
Site-specific protein modification using lipoic acid ligase and bis-aryl hydrazone formation.	Chembiochem : a European journal of chemical biology 20120416
Comparing intracellular stability and targeting of sulfobetaine quantum dots with other surface chemistries in live cells.	Small (Weinheim an der Bergstrasse, Germany) 20120410
On the pH-dependent quenching of quantum dot photoluminescence by redox active dopamine.	Journal of the American Chemical Society 20120404
Interchain acetyl transfer in the E2 component of bacterial pyruvate dehydrogenase suggests a model with different roles for each chain in a trimer of the homooligomeric component.	Biochemistry 20120403
Early- and advanced non-enzymatic glycation in diabetic vascular complications: the search for therapeutics.	Amino acids 20120401
General oxidative stress during doxorubicin-induced cardiotoxicity in rats: absence of cardioprotection and low antioxidant efficiency of alpha-lipoic acid.	Biochimie 20120401
Randomized phase III clinical trial of a combined treatment with carnitine + celecoxib ± megestrol acetate for patients with cancer-related anorexia/cachexia syndrome.	Clinical nutrition (Edinburgh, Scotland) 20120401
Randomized trials for the treatment of burning mouth syndrome: an evidence-based review of the literature.	Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology 20120401
Mutations in genes encoding the glycine cleavage system predispose to neural tube defects in mice and humans.	Human molecular genetics 20120401
alpha-lipoic acid prevents the induction of iNOS gene expression through destabilization of its mRNA in proinflammatory cytokine-stimulated hepatocytes.	Digestive diseases and sciences 20120401
UPEI-100, a conjugate of lipoic acid and apocynin, mediates neuroprotection in a rat model of ischemia/reperfusion.	American journal of physiology. Regulatory, integrative and comparative physiology 20120401
Acute reversal of endothelial dysfunction in the elderly after antioxidant consumption.	Hypertension (Dallas, Tex. : 1979) 20120401
α-Lipoic acid increases tolerance of cardiomyoblasts to glucose/glucose oxidase-induced injury via ROS-dependent ERK1/2 activation.	Biochimica et biophysica acta 20120401
Structure of the inclusion complex of β-cyclodextrin with lipoic acid from laboratory powder diffraction data.	Acta crystallographica. Section B, Structural science 20120401
The emergence and early evolution of biological carbon-fixation.	PLoS computational biology 20120401
Superior performance of range-separated hybrid functionals for describing σ* ← σ UV-vis signatures of three-electron two-center anions.	The journal of physical chemistry. A 20120329
Nrf2-dependent induction of proteasome and Pa28αβ regulator are required for adaptation to oxidative stress.	The Journal of biological chemistry 20120323
ROS-mediated lipopolysaccharide-induced apoptosis in INS-1 cells by modulation of Bcl-2 and Bax.	Cellular and molecular biology (Noisy-le-Grand, France) 20120323
Colloidal stability of gold nanoparticles modified with thiol compounds: bioconjugation and application in cancer cell imaging.	Langmuir : the ACS journal of surfaces and colloids 20120306
Alpha lipoic acid protects heart against myocardial ischemia-reperfusion injury through a mechanism involving aldehyde dehydrogenase 2 activation.	European journal of pharmacology 20120305
Modeling mitochondrial dysfunctions in the brain: from mice to men.	Journal of inherited metabolic disease 20120301
Effects of alpha-lipoic acid supplementation on inflammation, oxidative stress, and serum lipid profile levels in patients with end-stage renal disease on hemodialysis.	Journal of renal nutrition : the official journal of the Council on Renal Nutrition of the National Kidney Foundation 20120301
Protective effects of curcumin, α-lipoic acid, and N-acetylcysteine against carbon tetrachloride-induced liver fibrosis in rats.	Journal of physiology and biochemistry 20120301
Renal ischaemia/reperfusion injury: possible role of aquaporins.	Acta physiologica (Oxford, England) 20120301
Oxidative stress in preretinopathic diabetes subjects and antioxidants.	Diabetes technology & therapeutics 20120301
R-α-lipoic acid does not reverse hepatic inflammation of aging, but lowers lipid anabolism, while accentuating circadian rhythm transcript profiles.	American journal of physiology. Regulatory, integrative and comparative physiology 20120301
Changes in expression profiles of antioxidant enzymes in diabetic rat kidneys.	Diabetes/metabolism research and reviews 20120301
Mitochondrial lipoic acid scavenging is essential for Plasmodium berghei liver stage development.	Cellular microbiology 20120301
Reactive oxygen species are required for the hypothalamic osmoregulatory response.	Endocrinology 20120301
Lipoic acid attenuates high-fat-diet-induced oxidative stress and B-cell-related immune depression.	Nutrition (Burbank, Los Angeles County, Calif.) 20120301
Antiproliferative effects of a new α-lipoic acid derivative, DHL-HisZnNa, in HT29 human colon cancer cells in vitro.	Expert opinion on therapeutic targets 20120301
Combination of alpha lipoic acid and superoxide dismutase leads to physiological and symptomatic improvements in diabetic neuropathy.	Drugs in R&D 20120301
Biogenesis of iron-sulfur clusters in mammalian cells: new insights and relevance to human disease.	Disease models & mechanisms 20120301
[Alpha lipoic acid affect the function of EPCs incubated by high-glucose].	Xi bao yu fen zi mian yi xue za zhi = Chinese journal of cellular and molecular immunology 20120301
Oligomerized lychee fruit extract (OLFE) and a mixture of vitamin C and vitamin E for endurance capacity in a double blind randomized controlled trial.	Journal of clinical biochemistry and nutrition 20120301
Effects of coenzyme Q10 and α-lipoic acid supplementation in fructose fed rats.	Journal of clinical biochemistry and nutrition 20120301
Oxidative stress and benefits of antioxidant agents in acute and chronic hepatitis.	Hepatitis monthly 20120301
Fluorophore targeting to cellular proteins via enzyme-mediated azide ligation and strain-promoted cycloaddition.	Journal of the American Chemical Society 20120227
Poly(ethylene glycol)-based multidentate oligomers for biocompatible semiconductor and gold nanocrystals.	Langmuir : the ACS journal of surfaces and colloids 20120207
Playing with peptides: how to build a supramolecular peptide nanostructure by exploiting helix···helix macrodipole interactions.	Langmuir : the ACS journal of surfaces and colloids 20120207
Adding a combination of hydroxycitrate and lipoic acid (METABLOC™) to chemotherapy improves effectiveness against tumor development: experimental results and case report.	Investigational new drugs 20120201
α-Lipoic acid attenuates vascular calcification via reversal of mitochondrial function and restoration of Gas6/Axl/Akt survival pathway.	Journal of cellular and molecular medicine 20120201
Review of the literature and suggestions for the design of rodent survival studies for the identification of compounds that increase health and life span.	Age (Dordrecht, Netherlands) 20120201
Effects of oxidized cooking oil and α-lipoic acid on blood antioxidants: enzyme activities and lipid peroxidation in rats fed a high-fat diet.	Biological trace element research 20120201
Role of AMP-activated protein kinase in α-lipoic acid-induced vasodilatation in spontaneously hypertensive rats.	American journal of hypertension 20120201
Mixed SAMs and MALDI-ToF MS: preparation of N-glycosylamine derivative and thioctic acid methyl ester bearing 1,2-dithiolane groups and detection of enzymatic reaction on Au.	Bioorganic chemistry 20120201
A comparative assessment of α-lipoic acid N-phenylamides as non-steroidal androgen receptor antagonists both on and off gold nanoparticles.	Bioorganic chemistry 20120201
Dihydrolipoyl dioleoylglycerol antioxidant capacity in phospholipid vesicles.	Chemistry and physics of lipids 20120201
Effect of α-lipoic acid on platelet reactivity in type 1 diabetic patients.	Diabetes care 20120201
The effect of alpha lipoic acid on the developmental competence of mouse isolated preantral follicles.	Journal of assisted reproduction and genetics 20120201
α-Lipoic acid, diabetic neuropathy, and Nathan's prophecy.	Angiology 20120201
Inflammatory cause of metabolic syndrome via brain stress and NF-κB.	Aging 20120201
Modifications of andrographolide to increase some biological activities: a patent review (2006 - 2011).	Expert opinion on therapeutic patents 20120201
Metabolism and regulation of glycerolipids in the yeast Saccharomyces cerevisiae.	Genetics 20120201
Induction of ER Stress-Mediated Apoptosis by α-Lipoic Acid in A549 Cell Lines.	The Korean journal of thoracic and cardiovascular surgery 20120201
Diabetic peripheral neuropathy in type 2 diabetes mellitus in Korea.	Diabetes & metabolism journal 20120201
Five new amicoumacins isolated from a marine-derived bacterium Bacillus subtilis.	Marine drugs 20120201
DNA bimodified gold nanoparticles.	Langmuir : the ACS journal of surfaces and colloids 20120131
Alpha-lipoic acid attenuates methionine choline deficient diet-induced steatohepatitis in C57BL/6 mice.	Life sciences 20120130
Gold nanoparticles as a label-free probe for the detection of amyloidogenic protein.	Talanta 20120130
Bioorganic synthesis, characterization and antioxidant activity of esters of natural phenolics and α-lipoic acid.	Journal of biotechnology 20120120
Diels-Alder cycloaddition for fluorophore targeting to specific proteins inside living cells.	Journal of the American Chemical Society 20120118
Co-administration of apocynin with lipoic acid enhances neuroprotection in a rat model of ischemia/reperfusion.	Neuroscience letters 20120117
Reaction characteristics of andrographolide and its analogue AL-1 with GSH, as a simple chemical simulation of NF-κB inhibition.	Molecules (Basel, Switzerland) 20120112
α-Lipoic acid, a scavenging agent for H₂O₂, reduces ethanol-stimulated locomotion in mice.	Psychopharmacology 20120101
Mitochondrial calcium homeostasis as potential target for mitochondrial medicine.	Mitochondrion 20120101
Proteomic analysis of mitochondria in APOE transgenic mice and in response to an ischemic challenge.	Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 20120101
Effect of lipoic acid on expression of angiogenic factors in diabetic rat retina.	Clinical & experimental ophthalmology 20120101
Taurine reduces nitrosative stress and nitric oxide synthase expression in high glucose-exposed human Schwann cells.	Experimental neurology 20120101
Dietary oxidative stress and antioxidant defense with an emphasis on plant extract administration.	Cell stress & chaperones 20120101
Acetyl-L-carnitine and α-lipoic acid affect rotenone-induced damage in nigral dopaminergic neurons of rat brain, implication for Parkinson's disease therapy.	Pharmacology, biochemistry, and behavior 20120101
Insufficient endogenous redox buffer capacity may underlie neuronal vulnerability to cerebral ischemia and reperfusion.	Journal of neuroscience research 20120101
Reduced expression of lipoic acid synthase accelerates diabetic nephropathy.	Journal of the American Society of Nephrology : JASN 20120101
Evaluation of protective and curative role of α-lipoic acid and selenium in gentamicin-induced nephrotoxicity in rabbits.	Pakistan journal of pharmaceutical sciences 20120101
Betaine treatment attenuates chronic ethanol-induced hepatic steatosis and alterations to the mitochondrial respiratory chain proteome.	International journal of hepatology 20120101
The role of metformin in the management of NAFLD.	Experimental diabetes research 20120101
Sulphur-containing non enzymatic antioxidants: therapeutic tools against cancer.	Frontiers in bioscience (Scholar edition) 20120101
Oxidative Stress and Down Syndrome: A Route toward Alzheimer-Like Dementia.	Current gerontology and geriatrics research 20120101
Efficacy of cosmetic formulations containing dispersion of liposome with magnesium ascorbyl phosphate, alpha-lipoic acid and kinetin.	Photochemistry and photobiology 20120101
Integration of gene-based markers in a pearl millet genetic map for identification of candidate genes underlying drought tolerance quantitative trait loci.	BMC plant biology 20120101
Cellular dysfunction in diabetes as maladaptive response to mitochondrial oxidative stress.	Experimental diabetes research 20120101
Novel Neurovascular Protective Agents: Effects of INV-155, INV-157, INV-159, and INV-161 versus Lipoic Acid and Captopril in a Rat Stroke Model.	Cardiology research and practice 20120101
Activation of TRPV1 by capsaicin induces functional kinin B(1) receptor in rat spinal cord microglia.	Journal of neuroinflammation 20120101
A new model for raf kinase inhibitory protein induced chemotherapeutic resistance.	PloS one 20120101
Adaptation of Salmonella enterica Hadar under static magnetic field: effects on outer membrane protein pattern.	Proteome science 20120101
Environmental determinants of chronic disease and medical approaches: recognition, avoidance, supportive therapy, and detoxification.	Journal of environmental and public health 20120101
Brain insulin resistance and deficiency as therapeutic targets in Alzheimer's disease.	Current Alzheimer research 20120101
Alpha lipoic Acid for symptomatic peripheral neuropathy in patients with diabetes: a meta-analysis of randomized controlled trials.	International journal of endocrinology 20120101
Insight into the transmission biology and species-specific functional capabilities of tsetse (Diptera: glossinidae) obligate symbiont Wigglesworthia.	mBio 20120101
Inhibitory effect of 4-O-methylhonokiol on lipopolysaccharide-induced neuroinflammation, amyloidogenesis and memory impairment via inhibition of nuclear factor-kappaB in vitro and in vivo models.	Journal of neuroinflammation 20120101
Toward a Systemic Understanding of Listeria monocytogenes Metabolism during Infection.	Frontiers in microbiology 20120101
Mechanisms underlying skeletal muscle insulin resistance induced by fatty acids: importance of the mitochondrial function.	Lipids in health and disease 20120101
LAL regulators SCO0877 and SCO7173 as pleiotropic modulators of phosphate starvation response and actinorhodin biosynthesis in Streptomyces coelicolor.	PloS one 20120101
Glycemic and oxidative status of patients with type 2 diabetes mellitus following oral administration of alpha-lipoic acid: a randomized double-blinded placebo-controlled study.	Asia Pacific journal of clinical nutrition 20120101
Antioxidant therapies: a potential role in perinatal medicine.	Neuroendocrinology 20120101
Identifying low pH active and lactate-utilizing taxa within oral microbiome communities from healthy children using stable isotope probing techniques.	PloS one 20120101
Alleviative effects of α-lipoic acid supplementation on acute heat stress-induced thermal panting and the level of plasma nonesterified fatty acids in hypothyroid broiler chickens.	British poultry science 20120101
Antioxidant-induced stress.	International journal of molecular sciences 20120101
Conflict of evidence: carotenoids and other micronutrients in the prevention and treatment of cognitive impairment.	BioFactors (Oxford, England) 20120101
Improvements of insulin resistance in ovariectomized rats by a novel phytoestrogen from Curcuma comosa Roxb.	BMC complementary and alternative medicine 20120101
Glucagon-like peptides 1 and 2 and vasoactive intestinal peptide are neuroprotective on cultured and mast cell co-cultured rat myenteric neurons.	BMC gastroenterology 20120101
Major phenolic compounds, antioxidant capacity and antidiabetic potential of rice bean (Vigna umbellata L.) in China.	International journal of molecular sciences 20120101
Dihydrolipoic acid induces cytotoxicity in mouse blastocysts through apoptosis processes.	International journal of molecular sciences 20120101
Heme oxygenase-1 induction and organic nitrate therapy: beneficial effects on endothelial dysfunction, nitrate tolerance, and vascular oxidative stress.	International journal of hypertension 20120101
A versatile ΦC31 based reporter system for measuring AP-1 and Nrf2 signaling in Drosophila and in tissue culture.	PloS one 20120101
Sulforaphane potentiates RNA damage induced by different xenobiotics.	PloS one 20120101
Role of neural NO synthase (nNOS) uncoupling in the dysfunctional nitrergic vasorelaxation of penile arteries from insulin-resistant obese Zucker rats.	PloS one 20120101
Current view on phytoplasma genomes and encoded metabolism.	TheScientificWorldJournal 20120101
Etiopathogenesis of insulin autoimmunity.	Anatomy research international 20120101
Induction of oxidative stress in kidney.	International journal of nephrology 20120101
Trace elements affect methanogenic activity and diversity in enrichments from subsurface coal bed produced water.	Frontiers in microbiology 20120101
Ca2+/calmodulin-dependent protein kinase kinase is not involved in hypothalamic AMP-activated protein kinase activation by neuroglucopenia.	PloS one 20120101
Improvement of genetic stability in lymphocytes from Fanconi anemia patients through the combined effect of α-lipoic acid and N-acetylcysteine.	Orphanet journal of rare diseases 20120101
Resveratrol-loaded solid lipid nanoparticles versus nanostructured lipid carriers: evaluation of antioxidant potential for dermal applications.	International journal of nanomedicine 20120101
Tackling Chemotherapy-induced Alopecia.	International journal of trichology 20120101
Enhancement of lipid stability of broiler breast meat and meat products fed on alpha lipoic acid and alpha tocopherol acetate supplemented feed.	Lipids in health and disease 20120101
Oxidative stress and heart failure in altered thyroid States.	TheScientificWorldJournal 20120101
The effects of the melatonin treatment on the oxidative stress and apoptosis in diabetic eye and brain.	TheScientificWorldJournal 20120101
A combination of lipoic acid plus coenzyme Q10 induces PGC1α, a master switch of energy metabolism, improves stress response, and increases cellular glutathione levels in cultured C2C12 skeletal muscle cells.	Oxidative medicine and cellular longevity 20120101
Bioactive dietary supplements reactivate ER expression in ER-negative breast cancer cells by active chromatin modifications.	PloS one 20120101
Anti-inflammatory and antinociceptive effects of salbutamol on acute and chronic models of inflammation in rats: involvement of an antioxidant mechanism.	Mediators of inflammation 20120101
Schisandrin B as a hormetic agent for preventing age-related neurodegenerative diseases.	Oxidative medicine and cellular longevity 20120101
Effect of (R)-α-lipoic acid supplementation on serum lipids and antioxidative ability in patients with age-related macular degeneration.	Annals of nutrition & metabolism 20120101
The antioxidant mechanisms underlying the aged garlic extract- and S-allylcysteine-induced protection.	Oxidative medicine and cellular longevity 20120101
Oxidative stress in 5/6 nephrectomized rat model: effect of alpha-lipoic acid.	Renal failure 20120101
Comparative geno-plasticity analysis of Mycoplasma bovis HB0801 (Chinese isolate).	PloS one 20120101
Inhibition of gene expression of organic cation/carnitine transporter and antioxidant enzymes in oxazaphosphorines-induced acute cardiomyopathic rat models.	Oxidative medicine and cellular longevity 20120101
The antioxidant role of xanthurenic acid in the Aedes aegypti midgut during digestion of a blood meal.	PloS one 20120101
Recent advances in the treatment of neurodegenerative diseases based on GSH delivery systems.	Oxidative medicine and cellular longevity 20120101
Antioxidants in kidney diseases: the impact of bardoxolone methyl.	International journal of nephrology 20120101
TGF-β(2)- and H(2)O(2)-induced biological changes in optic nerve head astrocytes are reduced by the antioxidant alpha-lipoic acid.	Ophthalmic research 20120101
Cardiac fibrosis and dysfunction in experimental diabetic cardiomyopathy are ameliorated by alpha-lipoic acid.	Cardiovascular diabetology 20120101
Label-free capacitive DNA sensor using immobilized pyrrolidinyl PNA probe: effect of the length and terminating head group of the blocking thiols.	Biosensors & bioelectronics 20120101
Effect of alpha-lipoic acid on memory, oxidation, and lifespan in SAMP8 mice.	Journal of Alzheimer's disease : JAD 20120101
Effects of heat treatment on structural modification and in vivo antioxidant capacity of soy protein.	Nutrition (Burbank, Los Angeles County, Calif.) 20120101
Assessment of a standardized ROS production profile in humans by electron paramagnetic resonance.	Oxidative medicine and cellular longevity 20120101
Restoration of dioxin-induced damage to fetal steroidogenesis and gonadotropin formation by maternal co-treatment with α-lipoic acid.	PloS one 20120101
L-2-Oxothiazolidine-4-carboxylic acid or α-lipoic acid attenuates airway remodeling: involvement of nuclear factor-κB (NF-κB), nuclear factor erythroid 2p45-related factor-2 (Nrf2), and hypoxia-inducible factor (HIF).	International journal of molecular sciences 20120101
Development of quinoxaline 1, 4-dioxides resistance in Escherichia coli and molecular change under resistance selection.	PloS one 20120101
Alfa-lipoic acid controls tumor growth and modulates hepatic redox state in Ehrlich-ascites-carcinoma-bearing mice.	TheScientificWorldJournal 20120101
Protective effects of glutathione and lipoic acid against cadmium-induced oxidative stress in rat's kidney.	Renal failure 20120101
Uptake of biotin by Chlamydia Spp. through the use of a bacterial transporter (BioY) and a host-cell transporter (SMVT).	PloS one 20120101
Compromised mitochondrial fatty acid synthesis in transgenic mice results in defective protein lipoylation and energy disequilibrium.	PloS one 20120101
Lipoic acid synthetase deficiency causes neonatal-onset epilepsy, defective mitochondrial energy metabolism, and glycine elevation.	American journal of human genetics 20111209
Self-complementary recognition of supramolecular urea-aminotriazines in solution and on surfaces.	Langmuir : the ACS journal of surfaces and colloids 20111206
Lipoic acid modified low molecular weight polyethylenimine mediates nontoxic and highly potent in vitro gene transfection.	Molecular pharmaceutics 20111205
Biodegradable microspheres loaded with an anti-Parkinson prodrug: an in vivo pharmacokinetic study.	Molecular pharmaceutics 20111205
Dietary alpha lipoic acid supplementation prevents synovial inflammation and bone destruction in collagen-induced arthritic mice.	Rheumatology international 20111201
Palladium-α-lipoic acid complex attenuates alloxan-induced hyperglycemia and enhances the declined blood antioxidant status in diabetic rats.	Journal of diabetes 20111201
Intervention of mitochondrial dysfunction-oxidative stress-dependent apoptosis as a possible neuroprotective mechanism of α-lipoic acid against rotenone-induced parkinsonism and L-dopa toxicity.	Neuroscience research 20111201
Neuroprotective and anti-oxidative effects of the hemodialysate actovegin on primary rat neurons in vitro.	Neuromolecular medicine 20111201
α-Lipoic acid (LA) enantiomers protect SH-SY5Y cells against glutathione depletion.	Neurochemistry international 20111201
Direct analysis of carbohydrates in animal plasma by ion chromatography coupled with mass spectrometry and pulsed amperometric detection for use as a non-invasive diagnostic tool.	Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20111201
Formation of dopamine quinone-DNA adducts and their potential role in the etiology of Parkinson's disease.	IUBMB life 20111201
Suppression of high pacing-induced ANP secretion by antioxidants in isolated rat atria.	Peptides 20111201
A systematic screen to discover and analyze apicoplast proteins identifies a conserved and essential protein import factor.	PLoS pathogens 20111201
Single dose bioavailability and pharmacokinetic study of a innovative formulation of α-lipoic acid (ALA600) in healthy volunteers.	Minerva medica 20111201
Abstracts of the 6th cachexia conference, milan, Italy, december 8-10, 2011.	Journal of cachexia, sarcopenia and muscle 20111201
Reversibly crosslinked poly(vinyl alcohol) nanoparticles for triggered release of doxorubicin.	Journal of controlled release : official journal of the Controlled Release Society 20111130
Thermosensitive dendrimer formulation for drug delivery at physiologically relevant temperatures.	Chemical communications (Cambridge, England) 20111128
Mutations in the dimer interface of dihydrolipoamide dehydrogenase promote site-specific oxidative damages in yeast and human cells.	The Journal of biological chemistry 20111118
A fatal mitochondrial disease is associated with defective NFU1 function in the maturation of a subset of mitochondrial Fe-S proteins.	American journal of human genetics 20111111
Thioredoxin and dihydrolipoic acid are required for 3-mercaptopyruvate sulfurtransferase to produce hydrogen sulfide.	The Biochemical journal 20111101
Electrophile-modified lipoic derivatives of PDC-E2 elicits anti-mitochondrial antibody reactivity.	Journal of autoimmunity 20111101
Non-redox-active lipoate derivates disrupt cancer cell mitochondrial metabolism and are potent anticancer agents in vivo.	Journal of molecular medicine (Berlin, Germany) 20111101
Mapping the lipoylation site of Arabidopsis thaliana plastidial dihydrolipoamide S-acetyltransferase using mass spectrometry and site-directed mutagenesis.	Plant physiology and biochemistry : PPB 20111101
Alpha-lipoic acid protects against myocardial ischemia/reperfusion injury via multiple target effects.	Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20111101
Lipoic acid attenuates innate immune infiltration and activation in the visceral adipose tissue of obese insulin resistant mice.	Lipids 20111101
Exploiting the lipoic acid structure in the search for novel multitarget ligands against Alzheimer's disease.	European journal of medicinal chemistry 20111101
Role of mitochondria biogenesis in the metabolic memory associated with the continued progression of diabetic retinopathy and its regulation by lipoic acid.	Investigative ophthalmology & visual science 20111101
Dihydrolipoyl histidinate zinc complex, a new antioxidant, attenuates hepatic ischemia-reperfusion injury in rats.	Journal of gastroenterology and hepatology 20111101
Multitarget-directed ligands: innovative chemical probes and therapeutic tools against Alzheimer's disease.	Current topics in medicinal chemistry 20111101
Metabolic correction in the management of diabetic peripheral neuropathy: improving clinical results beyond symptom control.	Current clinical pharmacology 20111101
Dietary açai modulates ROS production by neutrophils and gene expression of liver antioxidant enzymes in rats.	Journal of clinical biochemistry and nutrition 20111101
Antioxidant composition causes antiexsudorific effect in the model of chronic venous insufficiency.	Bulletin of experimental biology and medicine 20111101
Protective effect of acetyl-l-carnitine and α-lipoic acid against the acute toxicity of diepoxybutane to human lymphocytes.	Toxicology 20111028
Signaling of hypochlorous acid by selective deprotection of dithiane. [corrected].	Organic & biomolecular chemistry 20111021
Oxidative damage compromises energy metabolism in the axonal degeneration mouse model of X-adrenoleukodystrophy.	Antioxidants & redox signaling 20111015
A simple, label-free AuNPs-based colorimetric ultrasensitive detection of nerve agents and highly toxic organophosphate pesticide.	Biosensors & bioelectronics 20111015
Insulin resistance due to nutrient excess: is it a consequence of AMPK downregulation?	Cell cycle (Georgetown, Tex.) 20111015
Mutations in iron-sulfur cluster scaffold genes NFU1 and BOLA3 cause a fatal deficiency of multiple respiratory chain and 2-oxoacid dehydrogenase enzymes.	American journal of human genetics 20111007
The effect of uremic toxin cyanate (OCN–) on anaerobic sulfur metabolism and prooxidative processes in the rat kidney: a protective role of lipoate.	Human & experimental toxicology 20111001
Short-term oral α-lipoic acid does not prevent lipid-induced dysregulation of glucose homeostasis in obese and overweight nondiabetic men.	American journal of physiology. Endocrinology and metabolism 20111001
Abrogation of cisplatin-induced nephrotoxicity in mice by alpha lipoic acid through ameliorating oxidative stress and enhancing gene expression of antioxidant enzymes.	European journal of pharmacology 20111001
Full-spectrum antioxidant therapy featuring astaxanthin coupled with lipoprivic strategies and salsalate for management of non-alcoholic fatty liver disease.	Medical hypotheses 20111001
Effects of a new synthetic butyrylcholinesterase inhibitor, HBU-39, on cell proliferation and neuroblast differentiation in the hippocampal dentate gyrus in a scopolamine-induced amnesia animal model.	Neurochemistry international 20111001
CD55 deficiency protects against atherosclerosis in ApoE-deficient mice via C3a modulation of lipid metabolism.	The American journal of pathology 20111001
Design, synthesis and evaluation of PEGylated lipoic acid derivatives with functionality as potent anti-melanogenic agents.	European journal of medicinal chemistry 20111001
Selective responses of myenteric neurons to oxidative stress and diabetic stimuli.	Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society 20111001
Reversible human serum albumin binding of lipocrine: a circular dichroism study.	Chirality 20111001
Impact of α-lipoic acid on liver peroxisome proliferator-activated receptor-α, vascular remodeling, and oxidative stress in insulin-resistant rats.	Canadian journal of physiology and pharmacology 20111001
Lipoic acid and moderate swimming improves the estrous cycle and oxidative stress in Wistar rats.	Applied physiology, nutrition, and metabolism = Physiologie appliquee, nutrition et metabolisme 20111001
Flavonoids: not just for cancer anymore.	Compendium (Yardley, PA) 20111001
Prevention of free fatty acid-induced hepatic lipotoxicity by carnitine via reversal of mitochondrial dysfunction.	Liver international : official journal of the International Association for the Study of the Liver 20111001
[The influence of lipoic acid on total protein concentration in the liver and spleen tissue in rats during lipopolysaccharide-induced oxidative stress].	Polski merkuriusz lekarski : organ Polskiego Towarzystwa Lekarskiego 20111001
Effects of α-lipoic acid and L-carnosine supplementation on antioxidant activities and lipid profiles in rats.	Nutrition research and practice 20111001
A novel piezoelectric immunosensor for the detection of malarial Plasmodium falciparum histidine rich protein-2 antigen.	Talanta 20110930
Structure-guided engineering of a Pacific Blue fluorophore ligase for specific protein imaging in living cells.	Biochemistry 20110927
Protection against genotoxic damages following whole body gamma radiation exposure in mice by lipoic acid.	Mutation research 20110918
Ibuprofen and lipoic acid codrug 1 control Alzheimer's disease progression by down-regulating protein kinase C ε-mediated metalloproteinase 2 and 9 levels in β-amyloid infused Alzheimer's disease rat model.	Brain research 20110915
A complex lipoate utilization pathway in Listeria monocytogenes.	The Journal of biological chemistry 20110909
Oxidative stress and the etiology of insulin resistance and type 2 diabetes.	Free radical biology & medicine 20110901
Does laryngopharyngeal reflux cause intraoral burning sensations? A preliminary study.	European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery 20110901
Effects of lipoic acid on apelin in 3T3-L1 adipocytes and in high-fat fed rats.	Journal of physiology and biochemistry 20110901
Reciprocal effects of α-lipoic acid on adenosine monophosphate-activated protein kinase activity in obesity induced by ovariectomy in rats.	Menopause (New York, N.Y.) 20110901
The effect of antioxidants on the response of the rabbit urinary bladder to in vitro ischemia/reperfusion.	Molecular and cellular biochemistry 20110901
Immunomodulatory effect of DL-α-lipoic acid in aged rats.	Experimental gerontology 20110901
Chemoprotection of lipoic acid against microcystin-induced toxicosis in common carp (Cyprinus carpio, Cyprinidae).	Comparative biochemistry and physiology. Toxicology & pharmacology : CBP 20110901
A translational continuum of model systems for evaluating treatment strategies in Alzheimer's disease: isradipine as a candidate drug.	Disease models & mechanisms 20110901
Efficacy and safety of antioxidant treatment with α-lipoic acid over 4 years in diabetic polyneuropathy: the NATHAN 1 trial.	Diabetes care 20110901
Insulin autoimmune syndrome induced by α-lipoic acid in a Caucasian woman: case report.	Diabetes care 20110901
Nutrition delivery for obese ICU patients: delivery issues, lack of guidelines, and missed opportunities.	JPEN. Journal of parenteral and enteral nutrition 20110901
Allopurinol reduces the lethality associated with acute renal failure induced by Crotalus durissus terrificus snake venom: comparison with probenecid.	PLoS neglected tropical diseases 20110901
[Role of lipoic acid in health and disease].	Polski merkuriusz lekarski : organ Polskiego Towarzystwa Lekarskiego 20110901
Beneficial effects of alpha lipoic acid on cerulein-induced experimental acute pancreatitis in rats.	Ulusal travma ve acil cerrahi dergisi = Turkish journal of trauma & emergency surgery : TJTES 20110901
Lipoic acid alters amino acid neurotransmitters content in rat hippocampus after pilocarpine-induced seizures.	Fundamental & clinical pharmacology 20110801
Combination of alpha lipoic acid and gabapentin, its efficacy in the treatment of Burning Mouth Syndrome: a randomized, double-blind, placebo controlled trial.	Medicina oral, patologia oral y cirugia bucal 20110801
The organellar genome and metabolic potential of the hydrogen-producing mitochondrion of Nyctotherus ovalis.	Molecular biology and evolution 20110801
α-Lipoic acid normalizes nociceptive neuronal activity at the spinal cord of diabetic rats.	Diabetes, obesity & metabolism 20110801
Surface-engineered quantum dots for the labeling of hydrophobic microdomains in bacterial biofilms.	Biomaterials 20110801
1,3-Dinitrobenzene-induced metabolic impairment through selective inactivation of the pyruvate dehydrogenase complex.	Toxicological sciences : an official journal of the Society of Toxicology 20110801
Quantification and morphometry of myenteric neurones in the jejunum of Holtzman rats (Rattus norvegicus).	Anatomia, histologia, embryologia 20110801
Amelioration of lipid abnormalities by α-lipoic acid through antioxidative and anti-inflammatory effects.	Obesity (Silver Spring, Md.) 20110801
Nutritional approaches to modulate oxidative stress in Alzheimer's disease.	Current Alzheimer research 20110801
Stable dye-labelled oligonucleotide-nanoparticle conjugates for nucleic acid detection.	Nanoscale 20110801
Photochemical stability of lipoic acid and its impact on skin ageing.	Free radical research 20110801
Down syndrome and dementia: a randomized, controlled trial of antioxidant supplementation.	American journal of medical genetics. Part A 20110801
Role of mercury toxicity in hypertension, cardiovascular disease, and stroke.	Journal of clinical hypertension (Greenwich, Conn.) 20110801
Nanoencapsulation improves the in vitro antioxidant activity of lipoic acid.	Journal of biomedical nanotechnology 20110801
Chemical rescue of malaria parasites lacking an apicoplast defines organelle function in blood-stage Plasmodium falciparum.	PLoS biology 20110801
Continuous-flow reactor-based synthesis of carbohydrate and dihydrolipoic acid-capped quantum dots.	Nature protocols 20110728
Multifunctional surface modification of gold-stabilized nanoparticles by bioorthogonal reactions.	Journal of the American Chemical Society 20110727
Effects of lipoic acid, caffeic acid and a synthesized lipoyl-caffeic conjugate on human hepatoma cell lines.	Molecules (Basel, Switzerland) 20110727
Single-molecule colocalization studies shed light on the idea of fully emitting versus dark single quantum dots.	Small (Weinheim an der Bergstrasse, Germany) 20110718
Arsenic-induced oxidative stress and its reversibility.	Free radical biology & medicine 20110715
A deficit in zinc availability can cause alterations in tubulin thiol redox status in cultured neurons and in the developing fetal rat brain.	Free radical biology & medicine 20110715
Electrochemical analysis of HIV-1 reverse transcriptase serum level: exploiting protein binding to a functionalized nanostructured surface.	Talanta 20110715
Identification of N-propylnoraporphin-11-yl 5-(1,2-dithiolan-3-yl)pentanoate as a new anti-Parkinson's agent possessing a dopamine D2 and serotonin 5-HT1A dual-agonist profile.	Journal of medicinal chemistry 20110714
Lipid stability and antioxidant profile of microsomal fraction of broiler meat enriched with α-lipoic acid and α-tocopherol acetate.	Journal of agricultural and food chemistry 20110713
Lipoic acid stimulates cAMP production via G protein-coupled receptor-dependent and -independent mechanisms.	The Journal of nutritional biochemistry 20110701
Lipoic acid inhibits leptin secretion and Sp1 activity in adipocytes.	Molecular nutrition & food research 20110701
The effect of the uremic toxin cyanate (CNO⁻) on anaerobic cysteine metabolism and oxidative processes in the rat liver: a protective effect of lipoate.	Toxicology mechanisms and methods 20110701
Synthesis and biological evaluations of novel apocynin analogues.	European journal of medicinal chemistry 20110701
Suppression of the later stages of radiation-induced carcinogenesis by antioxidant dietary formulations.	Radiation research 20110701
Bacterial cysteine desulfurases: versatile key players in biosynthetic pathways of sulfur-containing biofactors.	Applied microbiology and biotechnology 20110701
Selective binding of carbamate pesticides by self-assembled monolayers of calix[4]arene lipoic acid: wettability and impedance dual-signal response.	Organic letters 20110701
Thioctic acid-induced acute cholestatic hepatitis.	The Annals of pharmacotherapy 20110701
Antioxidants halt axonal degeneration in a mouse model of X-adrenoleukodystrophy.	Annals of neurology 20110701
The search for reliable biomarkers of disease in multiple chemical sensitivity and other environmental intolerances.	International journal of environmental research and public health 20110701
Salt-mediated self-assembly of thioctic acid on gold nanoparticles.	ACS nano 20110628
Multifunctional compact zwitterionic ligands for preparing robust biocompatible semiconductor quantum dots and gold nanoparticles.	Journal of the American Chemical Society 20110622
Linking of sensor molecules with amino groups to amino-functionalized AFM tips.	Bioconjugate chemistry 20110615
Simultaneous determination of lipoic acid (LA) and dihydrolipoic acid (DHLA) in human plasma using high-performance liquid chromatography coupled with electrochemical detection.	Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20110615
Neuropharmacological effects of lipoic acid and ubiquinone on the mRNA level of interleukin-1β and acetylcholinesterase activity in rat hippocampus after seizures.	Fundamental & clinical pharmacology 20110601
Effect of alpha lipoic acid on cardiac autonomic dysfunction and platelet reactivity in type 1 diabetes: rationale and design of the AUTOnomic function and platelet REACTivity trial (AUTO-REACT protocol).	Diabetes research and clinical practice 20110601
The proglycation effect of caffeic acid leads to the elevation of oxidative stress and inflammation in monocytes, macrophages and vascular endothelial cells.	The Journal of nutritional biochemistry 20110601
Antioxidant supplementation reduces skeletal muscle mitochondrial biogenesis.	Medicine and science in sports and exercise 20110601
Role of obesity-associated dysfunctional adipose tissue in cancer: a molecular nutrition approach.	Biochimica et biophysica acta 20110601
Testicular oxidative damage and role of combined antioxidant supplementation in experimental diabetic rats.	Journal of physiology and biochemistry 20110601
An antioxidant screening assay based on oxidant-induced growth arrest in Saccharomyces cerevisiae.	FEMS yeast research 20110601
Suppression of growth and invasive behavior of human prostate cancer cells by ProstaCaid™: mechanism of activity.	International journal of oncology 20110601
Glycine cleavage enzyme complex: molecular cloning and expression of the H-protein cDNA from cultured human skin fibroblasts.	Biochemistry and cell biology = Biochimie et biologie cellulaire 20110601
Alpha-lipoic acid inhibits endoplasmic reticulum stress-induced cell death through PI3K/Akt signaling pathway in FRTL5 thyroid cells.	Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme 20110601
Effect of alpha-lipoic acid on blood glucose, insulin resistance and glutathione peroxidase of type 2 diabetic patients.	Saudi medical journal 20110601
Loss of taste responds to high-dose biotin treatment.	Journal of the American College of Nutrition 20110601
Environmental pathways to autoimmune diseases: the cases of primary biliary cirrhosis and multiple sclerosis.	Archives of medical science : AMS 20110601
A new strategy improves assembly efficiency of DNA mono-modified gold nanoparticles.	Chemical communications (Cambridge, England) 20110528
Preparation and characterization of poly(lactic-co-glycolic acid) microspheres loaded with a labile antiparkinson prodrug.	International journal of pharmaceutics 20110516
Photoswitchable rotaxanes on gold nanoparticles.	Organic & biomolecular chemistry 20110507
Effects of combination tocopherols and alpha lipoic acid therapy on oxidative stress and inflammatory biomarkers in chronic kidney disease.	Journal of renal nutrition : the official journal of the Council on Renal Nutrition of the National Kidney Foundation 20110501
Essential role of ERK activation in neurite outgrowth induced by α-lipoic acid.	Biochimica et biophysica acta 20110501
The effects of lipoic acid and α-tocopherol supplementation on the lipid profile and insulin sensitivity of patients with type 2 diabetes mellitus: a randomized, double-blind, placebo-controlled trial.	Diabetes research and clinical practice 20110501
Analysis of the efficacy, safety, and regulatory status of novel forms of creatine.	Amino acids 20110501
The creatine kinase system and pleiotropic effects of creatine.	Amino acids 20110501
The α-lipoic acid derivative sodium zinc dihydrolipoylhistidinate reduces chemotherapy-induced alopecia in a rat model: a pilot study.	Surgery today 20110501
Evolving coronary stents coated with new bioactive agents.	Korean circulation journal 20110501
Effect of a dual drug-coated stent with abciximab and alpha-lipoic Acid in a porcine coronary restenosis model.	Korean circulation journal 20110501
Lipoic acid ameliorates arsenic trioxide-induced HO-1 expression and oxidative stress in THP-1 monocytes and macrophages.	Chemico-biological interactions 20110425
Proflavine derivatives as fluorescent imaging agents of amyloid deposits.	Bioorganic & medicinal chemistry letters 20110415
Synthesis and biological evaluation of 3,7-diazabicyclo[4.3.0]nonan-8-ones as potential nootropic and analgesic drugs.	Journal of medicinal chemistry 20110414
Inhibitory effect of α-lipoic acid on platelet aggregation is mediated by PPARs.	Journal of agricultural and food chemistry 20110413
Effects of lipoic acid on antiapoptotic genes in control and ethanol-treated fetal rhombencephalic neurons.	Brain research 20110406
Hybrid lipoic acid derivatives to attack prion disease on multiple fronts.	ChemMedChem 20110404
Neuropharmacological effects of lipoic acid and ubiquinone on δ-aminolevulinic dehydratase, Na(+) , K(+) -ATPase, and Mg(2+) -ATPase activities in rat hippocampus after pilocarpine-induced seizures.	Fundamental & clinical pharmacology 20110401
Metabolic manipulators: a well founded strategy to combat mitochondrial dysfunction.	Journal of inherited metabolic disease 20110401
Antipsychotic-induced DRD2 upregulation and its prevention by α-lipoic acid in SH-SY5Y neuroblastoma cells.	Synapse (New York, N.Y.) 20110401
Age-related oxidative decline of mitochondrial functions in rat brain is prevented by long term oral antioxidant supplementation.	Biogerontology 20110401
Self-medication of migraine and tension-type headache: summary of the evidence-based recommendations of the Deutsche Migräne und Kopfschmerzgesellschaft (DMKG), the Deutsche Gesellschaft für Neurologie (DGN), the Österreichische Kopfschmerzgesellschaft (ÖKSG) and the Schweizerische Kopfwehgesellschaft (SKG).	The journal of headache and pain 20110401
Cellular mechanisms by which lipoic acid confers protection during the early stages of cerebral ischemia: a possible role for calcium.	Neuroscience research 20110401
Lipoic acid decreases inflammation and confers neuroprotection in experimental autoimmune optic neuritis.	Journal of neuroimmunology 20110401
α-lipoic acid can improve endothelial dysfunction in subjects with impaired fasting glucose.	Metabolism: clinical and experimental 20110401
Nutritional supplements and their effect on glucose control.	Current diabetes reports 20110401
A novel two-gene requirement for the octanoyltransfer reaction of Bacillus subtilis lipoic acid biosynthesis.	Molecular microbiology 20110401
A novel amidotransferase required for lipoic acid cofactor assembly in Bacillus subtilis.	Molecular microbiology 20110401
Epigenetic changes in mitochondrial superoxide dismutase in the retina and the development of diabetic retinopathy.	Diabetes 20110401
Lipoic acid increases the expression of genes involved in bone formation in mice fed a high-fat diet.	Nutrition research (New York, N.Y.) 20110401
[Extract of Ginkgo biloba and alpha-lipoic acid attenuate advanced glycation end products accumulation and RAGE expression in diabetic nephropathy rats].	Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine 20110401
α-Lipoic acid inhibits liver fibrosis through the attenuation of ROS-triggered signaling in hepatic stellate cells activated by PDGF and TGF-β.	Toxicology 20110328
Substrate and inhibitor specificities differ between human cytosolic and mitochondrial thioredoxin reductases: Implications for development of specific inhibitors.	Free radical biology & medicine 20110315
Protein-protein interactions in assembly of lipoic acid on the 2-oxoacid dehydrogenases of aerobic metabolism.	The Journal of biological chemistry 20110311
Carbonic anhydrase activators: gold nanoparticles coated with derivatized histamine, histidine, and carnosine show enhanced activatory effects on several mammalian isoforms.	Journal of medicinal chemistry 20110310
Differential effects of coenzyme Q10 and α-lipoic acid on two models of in vitro oxidative damage to the rabbit urinary bladder.	International urology and nephrology 20110301
Protective, antioxidative and antiapoptotic effects of 2-methoxy-6-acetyl-7-methyljuglone from Polygonum cuspidatum in PC12 cells.	Planta medica 20110301
Evidence that α-lipoic acid inhibits NF-κB activation independent of its antioxidant function.	Inflammation research : official journal of the European Histamine Research Society ... [et al.] 20110301
A combination of melatonin and alpha lipoic acid has greater cardioprotective effect than either of them singly against cadmium-induced oxidative damage.	Cardiovascular toxicology 20110301
Lipoamide or lipoic acid stimulates mitochondrial biogenesis in 3T3-L1 adipocytes via the endothelial NO synthase-cGMP-protein kinase G signalling pathway.	British journal of pharmacology 20110301
Mitochondrial optic neuropathies - disease mechanisms and therapeutic strategies.	Progress in retinal and eye research 20110301
Protective role of exogenous α-lipoic acid (ALA) on hippocampal antioxidant status and memory function in rat pups exposed to sodium arsenite during the early post-natal period.	Toxicology mechanisms and methods 20110301
New lipoic acid derivative drug sodium zinc dihydrolipoylhistidinate prevents cardiac dysfunction in an isolated perfused rat heart model.	Critical care medicine 20110301
Mitochondrion-specific antioxidants as drug treatments for Alzheimer disease.	CNS & neurological disorders drug targets 20110301
Antioxidants in the treatment of diabetes.	Current diabetes reviews 20110301
The effects of thrombin and cytokines upon the biomechanics and remodeling of isolated amnion membrane, in vitro.	Placenta 20110301
Effects of intragastric fructose and dextrose on mesenteric microvascular inflammation and postprandial hyperemia in the rat.	JPEN. Journal of parenteral and enteral nutrition 20110301
Antioxidative effects of N-acetylcysteine, lipoic acid, taurine, and curcumin in the muscle of Cyprinus carpio L. exposed to cadmium.	Arhiv za higijenu rada i toksikologiju 20110301
Alleviation of lindane induced toxicity in testis of Swiss mice (Mus musculus) by combined treatment with vitamin C, vitamin E and alpha-lipoic acid.	Indian journal of experimental biology 20110301
[The effect of oral alpha-lipoic acid in overweight/obese individuals on brachial-ankle pulse wave velocity and supine blood pressure: a randomized, crossover, double-blind, placebo-controlled trial].	Zhonghua liu xing bing xue za zhi = Zhonghua liuxingbingxue zazhi 20110301
Metabolite cross-feeding enhances virulence in a model polymicrobial infection.	PLoS pathogens 20110301
Utilization of adjuvant arthritis model for evaluation of new approaches in rheumatoid arthritis therapy focused on regulation of immune processes and oxidative stress.	Interdisciplinary toxicology 20110301
The new pyridoindole antioxidant SMe1EC2 and its intervention in hypoxia/hypoglycemia-induced impairment of longterm potentiation in rat hippocampus.	Interdisciplinary toxicology 20110301
Lipoic acid protects against reperfusion injury in the early stages of cerebral ischemia.	Brain research 20110223
Towards an early diagnosis of HIV infection: an electrochemical approach for detection of HIV-1 reverse transcriptase enzyme.	The Analyst 20110221
Microwave-assisted functionalization of carbon nanohorns via [2+1] nitrenes cycloaddition.	Chemical communications (Cambridge, England) 20110207
Chronic pretreatment with acetyl-L-carnitine and ±DL-α-lipoic acid protects against acute glutamate-induced neurotoxicity in rat brain by altering mitochondrial function.	Neurotoxicity research 20110201
Dyslipidemic high-fat diet affects adversely bone metabolism in mice associated with impaired antioxidant capacity.	Nutrition (Burbank, Los Angeles County, Calif.) 20110201
Degradation of 4-n-nonylphenol under nitrate reducing conditions.	Biodegradation 20110201
Colonic motor dysfunction in human diabetes is associated with enteric neuronal loss and increased oxidative stress.	Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society 20110201
The role of lipid peroxidation products and oxidative stress in activation of the canonical wingless-type MMTV integration site (WNT) pathway in a rat model of diabetic retinopathy.	Diabetologia 20110201
The contributions of antioxidant activity of lipoic acid in reducing neurogenerative progression of Parkinson's disease: a review.	The International journal of neuroscience 20110201
α-Lipoic acid suppresses the development of DNFB-induced atopic dermatitis-like symptoms in NC/Nga mice.	Experimental dermatology 20110201
Synthesis and effects of some novel tetrahydronaphthalene derivatives on proliferation and nitric oxide production in lipopolysaccharide activated Raw 264.7 macrophages.	European journal of medicinal chemistry 20110201
Alpha-lipoic acid rebalances redox and immune-testicular milieu in septic rats.	Chemico-biological interactions 20110201
Oxidative stress: key player in gastrointestinal complications of diabetes.	Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society 20110201
Participation of hindbrain AMP-activated protein kinase in glucoprivic feeding.	Diabetes 20110201
Protection of flunarizine on cerebral mitochondria injury induced by cortical spreading depression under hypoxic conditions.	The journal of headache and pain 20110201
Protective role of lipoic acid on methotrexate induced intestinal damage in rabbit model.	Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology 20110201
Water-soluble semiconductor nanocrystals cap exchanged with metalated ligands.	ACS nano 20110125
Cisplatin-induced cardiotoxicity: Mechanisms and cardioprotective strategies.	European journal of pharmacology 20110110
Surprising substrate versatility in SLC5A6: Na+-coupled I- transport by the human Na+/multivitamin transporter (hSMVT).	The Journal of biological chemistry 20110107
Theories and management of aging: modern and ayurveda perspectives.	Evidence-based complementary and alternative medicine : eCAM 20110101
Assessment of the Antioxidant and Reactive Oxygen Species Scavenging Activity of Methanolic Extract of Caesalpinia crista Leaf.	Evidence-based complementary and alternative medicine : eCAM 20110101
The Role of Th17 in Neuroimmune Disorders: Target for CAM Therapy. Part II.	Evidence-based complementary and alternative medicine : eCAM 20110101
Inhibition of inflammatory gene expression in keratinocytes using a composition containing carnitine, thioctic Acid and saw palmetto extract.	Evidence-based complementary and alternative medicine : eCAM 20110101
Role of lipoic acid on insulin resistance and leptin in experimentally diabetic rats.	Journal of diabetes and its complications 20110101
Alpha-lipoic acid protects against potassium cyanide-induced seizures and mortality.	Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie 20110101
α-Lipoic acid protects diabetic apolipoprotein E-deficient mice from nephropathy.	Journal of diabetes and its complications 20110101
Effects of selenite and chelating agents on mammalian thioredoxin reductase inhibited by mercury: implications for treatment of mercury poisoning.	FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20110101
(R)-α-Lipoic acid treatment restores ceramide balance in aging rat cardiac mitochondria.	Pharmacological research 20110101
Inhibition of aldehyde dehydrogenase 2 by oxidative stress is associated with cardiac dysfunction in diabetic rats.	Molecular medicine (Cambridge, Mass.) 20110101
Modulatory effects of lipoic acid and selenium against cadmium-induced biochemical alterations in testicular steroidogenesis.	Journal of biochemical and molecular toxicology 20110101
Identification of clinically used drugs that activate pregnane X receptors.	Drug metabolism and disposition: the biological fate of chemicals 20110101
The autoimmunity of primary biliary cirrhosis and the clonal selection theory.	Immunology and cell biology 20110101
α-Lipoic acid ameliorates foam cell formation via liver X receptor α-dependent upregulation of ATP-binding cassette transporters A1 and G1.	Free radical biology & medicine 20110101
Lipoic acid inhibits caspase-dependent and -independent cell death pathways and is neuroprotective against hippocampal damage after pilocarpine-induced seizures.	Pharmacology, biochemistry, and behavior 20110101
α-Lipoic acid has anti-inflammatory and anti-oxidative properties: an experimental study in rats with carrageenan-induced acute and cotton pellet-induced chronic inflammations.	The British journal of nutrition 20110101
Differential efficiency of simvastatin and lipoic acid treatments on Bothrops jararaca envenomation-induced acute kidney injury in mice.	Toxicon : official journal of the International Society on Toxinology 20110101
α-Ketoglutarate dehydrogenase: a mitochondrial redox sensor.	Free radical research 20110101
Synthesis of a novel ester of hydroxytyrosol and α-lipoic acid exhibiting an antiproliferative effect on human colon cancer HT-29 cells.	European journal of medicinal chemistry 20110101
Anti-oxidative effect of lipoic Acid in spinal cord ischemia/reperfusion.	Medical principles and practice : international journal of the Kuwait University, Health Science Centre 20110101
Effects of alpha-lipoic Acid on body weight in obese subjects.	The American journal of medicine 20110101
Is dental amalgam safe for humans? The opinion of the scientific committee of the European Commission.	Journal of occupational medicine and toxicology (London, England) 20110101
Immunomodulation of Autoimmune Arthritis by Herbal CAM.	Evidence-based complementary and alternative medicine : eCAM 20110101
Effects of lipoic acid on proliferation and apoptosis of liver cells in rats with metabolic stress.	Bulletin of experimental biology and medicine 20110101
Effect of pro- and antioxidants on insulin sensitivity and glucose tolerance.	Bulletin of experimental biology and medicine 20110101
What was lost in translation in the DHA trial is whom you should intend to treat.	Alzheimer's research & therapy 20110101
Protective effect of α-lipoic acid against arsenic trioxide-induced acute cardiac toxicity in rats.	Journal of pharmacological sciences 20110101
Lipoic acid: energy metabolism and redox regulation of transcription and cell signaling.	Journal of clinical biochemistry and nutrition 20110101
Integrative identification of Arabidopsis mitochondrial proteome and its function exploitation through protein interaction network.	PloS one 20110101
Metabolic reconstruction of the archaeon methanogen Methanosarcina Acetivorans.	BMC systems biology 20110101
Effects of rasagiline, its metabolite aminoindan and selegiline on glutamate receptor mediated signalling in the rat hippocampus slice in vitro.	BMC pharmacology 20110101
The biochemical and cellular basis for nutraceutical strategies to attenuate neurodegeneration in Parkinson's disease.	International journal of molecular sciences 20110101
Identification of surface proteins in Enterococcus faecalis V583.	BMC genomics 20110101
Conjugated Quantum Dots Inhibit the Amyloid β (1-42) Fibrillation Process.	International journal of Alzheimer's disease 20110101
[Tiolepta (thioctic acid) in the treatment of vibration disease].	Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova 20110101
A Regenerative Antioxidant Protocol of Vitamin E and α-Lipoic Acid Ameliorates Cardiovascular and Metabolic Changes in Fructose-Fed Rats.	Evidence-based complementary and alternative medicine : eCAM 20110101
Critical update for the clinical use of L-carnitine analogs in cardiometabolic disorders.	Vascular health and risk management 20110101
The aqueous solubility and thermal stability of α-lipoic acid are enhanced by cyclodextrin.	Bioscience, biotechnology, and biochemistry 20110101
[Neuroprotective effects of lipoic acid and superoxide dismutase in the rat model of cerebral ischemia].	Rossiiskii fiziologicheskii zhurnal imeni I.M. Sechenova 20110101
A study of toxicity and differential gene expression in murine liver following exposure to anti-malarial drugs: amodiaquine and sulphadoxine-pyrimethamine.	Malaria journal 20110101
Alpha lipoic acid treatment improved endothelium-dependent relaxation in diabetic rat aorta.	Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 20110101
Oxidative stress in dog with heart failure: the role of dietary Fatty acids and antioxidants.	Veterinary medicine international 20110101

Alpha-lipoic acid reduces methylmercury-induced neuronal injury in rat cerebral cortex via antioxidation pathways.

Environmental toxicology 20170301

α-Lipoic acid potentially targets AMP-activated protein kinase and energy production in the fetal brain to ameliorate dioxin-produced attenuation in fetal steroidogenesis.

The Journal of toxicological sciences 20170101

Role of Cyt-C/caspases-9,3, Bax/Bcl-2 and the FAS death receptor pathway in apoptosis induced by zinc oxide nanoparticles in human aortic endothelial cells and the protective effect by alpha-lipoic acid.

Chemico-biological interactions 20161025

Cardioprotective effects of lipoic acid, quercetin and resveratrol on oxidative stress related to thyroid hormone alterations in long-term obesity.

The Journal of nutritional biochemistry 20160701

Alpha lipoic acid supplementation attenuates reactive oxygen species in hypothalamic paraventricular nucleus and sympathoexcitation in high salt-induced hypertension.

Toxicology letters 20160122

Co-administration of α-lipoic acid and cyclosporine aggravates colon ulceration of acetic acid-induced ulcerative colitis via facilitation of NO/COX-2/miR-210 cascade.

Toxicology and applied pharmacology 20151101

Alpha-lipoic acid protects against cadmium-induced hepatotoxicity via calcium signalling and gap junctional intercellular communication in rat hepatocytes.

The Journal of toxicological sciences 20150801

α-Lipoic acid (α-LA) inhibits the transcriptional activity of interferon regulatory factor 1 (IRF-1) via SUMOylation.

Toxicology in vitro : an international journal published in association with BIBRA 20141001

Modulatory effects of curcumin, silybin-phytosome and alpha-R-lipoic acid against thioacetamide-induced liver cirrhosis in rats.

Chemico-biological interactions 20140605

α-Lipoic acid protects mitochondrial enzymes and attenuates lipopolysaccharide-induced hypothermia in mice.

Free radical biology & medicine 20140601

Arsenic trioxide induces unfolded protein response in vascular endothelial cells.

Archives of toxicology 20140201

Lipoamide channel-binding sulfonamides selectively inhibit mycobacterial lipoamide dehydrogenase.

Biochemistry 20131223

Lipoic acid mitigates bisphenol A-induced testicular mitochondrial toxicity in rats.

Toxicology and industrial health 20131101

Lipoic acid protects C6 cells against ammonia exposure through Na⁺-K⁺-Cl⁻ co-transporter and PKC pathway.

Toxicology in vitro : an international journal published in association with BIBRA 20131001

Inhibitory effect of α-lipoic acid on thioacetamide-induced tumor promotion through suppression of inflammatory cell responses in a two-stage hepatocarcinogenesis model in rats.

Chemico-biological interactions 20130925

Lipoic acid prevents Cr(6+) induced cell transformation and the associated genomic dysregulation.

Environmental toxicology and pharmacology 20130701

α-Lipoic acid protects against arsenic trioxide-induced acute QT prolongation in anesthetized guinea pigs.

European journal of pharmacology 20130405

Effects of lipoic acid on AMPK and adiponectin in adipose tissue of low- and high-fat-fed rats.

European journal of nutrition 20130301

Impact of dihydrolipoic acid on mouse embryonic stem cells and related regulatory mechanisms.

Environmental toxicology 20130201

Cytoprotective effect of alpha-lipoic acid on paraquat-exposed human bronchial epithelial cells via activation of nuclear factor erythroid related factor-2 pathway.

Biological & pharmaceutical bulletin 20130101

Interaction of 9,10-phenanthraquinone with dithiol causes oxidative modification of Cu,Zn-superoxide dismutase (SOD) through redox cycling.

The Journal of toxicological sciences 20130101

Lipoic acid administration prevents nonalcoholic steatosis linked to long-term high-fat feeding by modulating mitochondrial function.

The Journal of nutritional biochemistry 20121201

Functional and molecular aspects of biotin uptake via SMVT in human corneal epithelial (HCEC) and retinal pigment epithelial (D407) cells.

The AAPS journal 20121201

Impact of gold nanoparticle coating on redox homeostasis.

International journal of pharmaceutics 20121115

Neuroprotection of lipoic acid treatment promotes angiogenesis and reduces the glial scar formation after brain injury.

Neuroscience 20121108

α-lipoic acid prevents non-alcoholic fatty liver disease in OLETF rats.

Liver international : official journal of the International Association for the Study of the Liver 20121101

Effects of lipoic acid on lipolysis in 3T3-L1 adipocytes.

Journal of lipid research 20121101

Zinc and multi-mineral supplementation should mitigate the pathogenic impact of cadmium exposure.

Medical hypotheses 20121101

Alpha-lipoic acid induces sodium iodide symporter expression in TPC-1 thyroid cancer cell line.

Nuclear medicine and biology 20121101

Alpha-lipoic acid pre- and post-treatments provide protection against in vitro ischemia-reperfusion injury in cerebral endothelial cells via Akt/mTOR signaling.

Brain research 20121030

Preparation, characterization and efficacy evaluation of synthetic biocompatible polymers linking natural antioxidants.

Molecules (Basel, Switzerland) 20121026

Growth of in situ functionalized luminescent silver nanoclusters by direct reduction and size focusing.

ACS nano 20121023

Molecular expression and functional activity of sodium dependent multivitamin transporter in human prostate cancer cells.

International journal of pharmaceutics 20121015

Alpha-lipoic acid induces adipose triglyceride lipase expression and decreases intracellular lipid accumulation in HepG2 cells.

European journal of pharmacology 20121005

Photoinduced phase transfer of luminescent quantum dots to polar and aqueous media.

Journal of the American Chemical Society 20121003

Determination of lipoic acid, Trolox methyl ether and tocopherols in human plasma by liquid-chromatography and ion-trap tandem mass spectrometry.

Biomedical chromatography : BMC 20121001

Lipoic acid improves mitochondrial function in nonalcoholic steatosis through the stimulation of sirtuin 1 and sirtuin 3.

Obesity (Silver Spring, Md.) 20121001

Supplementation with antioxidants attenuates transient worsening of retinopathy in diabetes caused by acute intensive insulin therapy.

Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie 20121001

The protective effect of alpha lipoic acid on Schwann cells exposed to constant or intermittent high glucose.

Biochemical pharmacology 20121001

Protective effects of a novel synthetic α-lipoic acid-decursinol hybrid compound in experimentally induced transient cerebral ischemia.

Cellular and molecular neurobiology 20121001

α-Lipoic acid ameliorates impaired glucose uptake in LYRM1 overexpressing 3T3-L1 adipocytes through the IRS-1/Akt signaling pathway.

Journal of bioenergetics and biomembranes 20121001

A systematic review and meta-analysis of α-lipoic acid in the treatment of diabetic peripheral neuropathy.

European journal of endocrinology 20121001

Dietary supplementation with N-acetyl cysteine, α-tocopherol and α-lipoic acid reduces the extent of oxidative stress and proinflammatory state in aged rat brain.

Biogerontology 20121001

Sodium butyrate potentiates carbon tetrachloride-induced acute liver injury in mice.

Toxicology mechanisms and methods 20121001

Xenobiotics and autoimmunity: does acetaminophen cause primary biliary cirrhosis?

Trends in molecular medicine 20121001

Studies on synthesis and activation mechanism of mitomycin dimers connected by 1,2-dithiolane and diol linkers.

Bioorganic & medicinal chemistry 20121001

Chemerin and apelin are positively correlated with inflammation in obese type 2 diabetic patients.

Chinese medical journal 20121001

Neuroprotective effect of alpha-lipoic acid on hydrostatic pressure-induced damage of retinal ganglion cells in vitro.

Neuroscience letters 20120920

Chemiluminescence detection of amino acids and related compounds using acidic potassium permanganate, manganese(IV) or tris(2,2'-bipyridine)ruthenium(III).

Talanta 20120915

Modulatory effects of vitamin E, acetyl-L-carnitine and α-lipoic acid on new potential biomarkers for Alzheimer's disease in rat model.

Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie 20120901

Diffuse reflectance spectroscopy of fibrous proteins.

Amino acids 20120901

Bioactive compounds with effects on inflammation markers in humans.

International journal of food sciences and nutrition 20120901

Oxidative stress underlying axonal degeneration in adrenoleukodystrophy: a paradigm for multifactorial neurodegenerative diseases?

Biochimica et biophysica acta 20120901

Maternal antioxidants prevent β-cell apoptosis and promote formation of dual hormone-expressing endocrine cells in male offspring following fetal and neonatal nicotine exposure.

Journal of diabetes 20120901

Polychlorinated biphenyl quinone metabolites lead to oxidative stress in HepG2 cells and the protective role of dihydrolipoic acid.

Toxicology in vitro : an international journal published in association with BIBRA 20120901

Age and gender dependent bioavailability of R- and R,S-α-lipoic acid: a pilot study.

Pharmacological research 20120901

Targeting mitochondrial oxidative stress through lipoic acid synthase: a novel strategy to manage diabetic cardiovascular disease.

Cardiovascular & hematological agents in medicinal chemistry 20120901

Vascular function and the role of oxidative stress in heart failure, heart transplant, and beyond.

Hypertension (Dallas, Tex. : 1979) 20120901

Recent patents and developments in glaucoma biomarkers.

Recent patents on endocrine, metabolic & immune drug discovery 20120901

Reduction-responsive disassemblable core-cross-linked micelles based on poly(ethylene glycol)-b-poly(N-2-hydroxypropyl methacrylamide)-lipoic acid conjugates for triggered intracellular anticancer drug release.

Biomacromolecules 20120813

Screening of well-established drugs targeting cancer metabolism: reproducibility of the efficacy of a highly effective drug combination in mice.

Investigational new drugs 20120801

Therapeutic effect of alpha lipoic acid combined with praziquantel on liver fibrosis induced by Schistosoma mansoni challenged mice.

Parasitology research 20120801

Lipoic acid metabolism of Plasmodium--a suitable drug target.

Current pharmaceutical design 20120801

High-fat diets impair spatial learning of mice in the Y-maze paradigm: ameliorative potential of α-lipoic acid.

Journal of medicinal food 20120801

Retraction. Alpha-lipoic acid supplementation and diabetes.

Nutrition reviews 20120801

Pain Management in patients with diabetic nephropathy: the emerging role of α-lipoic acid.

Foot & ankle specialist 20120801

Direct enantioseparation of lipoic acid in dietary supplements by capillary electrophoresis using trimethyl-β-cyclodextrin as a chiral selector.

Electrophoresis 20120801

Microwave-assisted rapid synthesis of luminescent gold nanoclusters for sensing Hg2+ in living cells using fluorescence imaging.

Nanoscale 20120721

Syntheses and characterization of lisinopril-coated gold nanoparticles as highly stable targeted CT contrast agents in cardiovascular diseases.

Langmuir : the ACS journal of surfaces and colloids 20120717

Coenzyme Q10 deficiency in patients with Parkinson's disease.

Journal of the neurological sciences 20120715

Determination of lipoic acid by flow-injection and high-performance liquid chromatography with chemiluminescence detection.

Talanta 20120715

Combination pharmacotherapy for the treatment of neuropathic pain in adults.

The Cochrane database of systematic reviews 20120711

Identification and functional expression of the mitochondrial pyruvate carrier.

Science (New York, N.Y.) 20120706

Evaluation of the antioxidative capability of commonly used antioxidants in dermocosmetics by in vivo detection of protein carbonylation in human stratum corneum.

Journal of photochemistry and photobiology. B, Biology 20120702

GLUT1 deficiency syndrome in clinical practice.

Epilepsy research 20120701

The effects of gold nanoparticles in wound healing with antioxidant epigallocatechin gallate and α-lipoic acid.

Nanomedicine : nanotechnology, biology, and medicine 20120701

Quantum-chemical investigation of the structure and the antioxidant properties of α-lipoic acid and its metabolites.

Journal of molecular modeling 20120701

Antioxidants for Alzheimer disease: a randomized clinical trial with cerebrospinal fluid biomarker measures.

Archives of neurology 20120701

Regulation of inducible heme oxygenase and cyclooxygenase isozymes in a mouse model of spotted fever group rickettsiosis.

Microbial pathogenesis 20120701

Alfa-lipoic acid protects testosterone secretion pathway and sperm quality against 4-tert-octylphenol induced reproductive toxicity.

Ecotoxicology and environmental safety 20120701

Development of a simple and high-throughput method for detecting aflatoxins production in culture media.

Letters in applied microbiology 20120701

Alpha-lipoic acid reduces peridural fibrosis after laminectomy of lumbar vertebrae in rabbits.

Acta neurochirurgica 20120701

Reduced alpha-lipoic acid synthase gene expression exacerbates atherosclerosis in diabetic apolipoprotein E-deficient mice.

Atherosclerosis 20120701

Antioxidants and endothelial dysfunction in young and elderly people: is flow-mediated dilation useful to assess acute effects?

Hypertension (Dallas, Tex. : 1979) 20120701

A cost effective complement to managing the vitamin D deficient and anemic dialysis patient in the bundled world.

Nephrology news & issues 20120701

Effects of exercise and antioxidant supplementation on endothelial gene expression.

International journal of cardiology 20120628

Involvement of glutamate, oxidative stress and inducible nitric oxide synthase in the convulsant activity of ciprofloxacin in mice.

European journal of pharmacology 20120615

Lipoic acid prevents steroid-induced osteonecrosis in rabbits.

Rheumatology international 20120601

Effects of α-lipoic acid, vitamins E and C upon the heat stress in Japanese quails.

Journal of animal physiology and animal nutrition 20120601

The impact of lipoic acid on endothelial function and proteinuria in quinapril-treated diabetic patients with stage I hypertension: results from the QUALITY study.

Journal of cardiovascular pharmacology and therapeutics 20120601

α-Lipoic acid prevents mild portal endotoxaemia-induced hepatic inflammation and β cell dysfunction.

European journal of clinical investigation 20120601

Alpha-lipoic acid attenuates atherosclerotic lesions and inhibits proliferation of vascular smooth muscle cells through targeting of the Ras/MEK/ERK signaling pathway.

Molecular biology reports 20120601

New advances in the in-vitro culture of Dientamoeba fragilis.

Parasitology 20120601

Sodium dependent multivitamin transporter (SMVT): a potential target for drug delivery.

Current drug targets 20120601

Improvement of myocardial lipid accumulation and prevention of PGC-1α induction by fenofibrate.

Molecular medicine reports 20120601

α-Lipoic acid regulates lipid metabolism through induction of sirtuin 1 (SIRT1) and activation of AMP-activated protein kinase.

Diabetologia 20120601

Arsenic modulates heme oxygenase-1, interleukin-6, and vascular endothelial growth factor expression in endothelial cells: roles of ROS, NF-κB, and MAPK pathways.

Archives of toxicology 20120601

The role of natural killer (NK) and NK T cells in the loss of tolerance in murine primary biliary cirrhosis.

Clinical and experimental immunology 20120601

Cap-independent Nrf2 translation is part of a lipoic acid-stimulated detoxification stress response.

Biochimica et biophysica acta 20120601

The influence of EDDS on the metabolic and transcriptional responses induced by copper in hydroponically grown Brassica carinata seedlings.

Plant physiology and biochemistry : PPB 20120601

α-Lipoic acid protects 3T3-L1 adipocytes from NYGGF4 (PID1) overexpression-induced insulin resistance through increasing phosphorylation of IRS-1 and Akt.

Journal of bioenergetics and biomembranes 20120601

Evidence for using alpha-lipoic acid in reducing lipoprotein and inflammatory related atherosclerotic risk.

Journal of dietary supplements 20120601

α-lipoic acid inhibits high glucose-induced apoptosis in HIT-T15 cells.

Development, growth & differentiation 20120601

α-Lipoic acid reduced weight gain and improved the lipid profile in rats fed with high fat diet.

Nutrition research and practice 20120601

Ameliorating effect of DL-α-lipoic acid against cisplatin-induced nephrotoxicity and cardiotoxicity in experimental animals.

Drug discoveries & therapeutics 20120601

New α-lipoic acid derivative, DHL-HisZn, ameliorates renal ischemia-reperfusion injury in rats.

The Journal of surgical research 20120515

Biosynthetically intriguing chlorinated lipophilic metabolites from geographically distant tropical marine cyanobacteria.

The Journal of organic chemistry 20120504

Effect of α-lipoic acid on sperm quality, reproductive tract measures in thinner exposed rats.

Andrologia 20120501

Antioxidant-enriched diet does not delay the progression of age-related hearing loss.

Neurobiology of aging 20120501

ROS constitute a convergence nexus in the development of IGF1 resistance and impaired wound healing in a rat model of type 2 diabetes.

Disease models & mechanisms 20120501

Alpha lipoic acid selectively inhibits proliferation and adhesion to fibronectin of v-H-ras-transformed 3Y1 cells.

Journal of clinical biochemistry and nutrition 20120501

Nootropic activity of acetaminophen against colchicine induced cognitive impairment in rats.

Journal of clinical biochemistry and nutrition 20120501

Italian guidelines for primary headaches: 2012 revised version.

The journal of headache and pain 20120501

[Experience of diagnosis and treatment of phlegmon in the diabetic foot syndrome].

Klinichna khirurhiia 20120501

Treatment for mitochondrial disorders.

The Cochrane database of systematic reviews 20120418

Site-specific protein modification using lipoic acid ligase and bis-aryl hydrazone formation.

Chembiochem : a European journal of chemical biology 20120416

Comparing intracellular stability and targeting of sulfobetaine quantum dots with other surface chemistries in live cells.

Small (Weinheim an der Bergstrasse, Germany) 20120410

On the pH-dependent quenching of quantum dot photoluminescence by redox active dopamine.

Journal of the American Chemical Society 20120404

Interchain acetyl transfer in the E2 component of bacterial pyruvate dehydrogenase suggests a model with different roles for each chain in a trimer of the homooligomeric component.

Biochemistry 20120403

Early- and advanced non-enzymatic glycation in diabetic vascular complications: the search for therapeutics.

Amino acids 20120401

General oxidative stress during doxorubicin-induced cardiotoxicity in rats: absence of cardioprotection and low antioxidant efficiency of alpha-lipoic acid.

Biochimie 20120401

Randomized phase III clinical trial of a combined treatment with carnitine + celecoxib ± megestrol acetate for patients with cancer-related anorexia/cachexia syndrome.

Clinical nutrition (Edinburgh, Scotland) 20120401

Randomized trials for the treatment of burning mouth syndrome: an evidence-based review of the literature.

Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology 20120401

Mutations in genes encoding the glycine cleavage system predispose to neural tube defects in mice and humans.

Human molecular genetics 20120401

alpha-lipoic acid prevents the induction of iNOS gene expression through destabilization of its mRNA in proinflammatory cytokine-stimulated hepatocytes.

Digestive diseases and sciences 20120401

UPEI-100, a conjugate of lipoic acid and apocynin, mediates neuroprotection in a rat model of ischemia/reperfusion.

American journal of physiology. Regulatory, integrative and comparative physiology 20120401

Acute reversal of endothelial dysfunction in the elderly after antioxidant consumption.

Hypertension (Dallas, Tex. : 1979) 20120401

α-Lipoic acid increases tolerance of cardiomyoblasts to glucose/glucose oxidase-induced injury via ROS-dependent ERK1/2 activation.

Biochimica et biophysica acta 20120401

Structure of the inclusion complex of β-cyclodextrin with lipoic acid from laboratory powder diffraction data.

Acta crystallographica. Section B, Structural science 20120401

The emergence and early evolution of biological carbon-fixation.

PLoS computational biology 20120401

Superior performance of range-separated hybrid functionals for describing σ* ← σ UV-vis signatures of three-electron two-center anions.

The journal of physical chemistry. A 20120329

Nrf2-dependent induction of proteasome and Pa28αβ regulator are required for adaptation to oxidative stress.

The Journal of biological chemistry 20120323

ROS-mediated lipopolysaccharide-induced apoptosis in INS-1 cells by modulation of Bcl-2 and Bax.

Cellular and molecular biology (Noisy-le-Grand, France) 20120323

Colloidal stability of gold nanoparticles modified with thiol compounds: bioconjugation and application in cancer cell imaging.

Langmuir : the ACS journal of surfaces and colloids 20120306

Alpha lipoic acid protects heart against myocardial ischemia-reperfusion injury through a mechanism involving aldehyde dehydrogenase 2 activation.

European journal of pharmacology 20120305

Modeling mitochondrial dysfunctions in the brain: from mice to men.

Journal of inherited metabolic disease 20120301

Effects of alpha-lipoic acid supplementation on inflammation, oxidative stress, and serum lipid profile levels in patients with end-stage renal disease on hemodialysis.

Journal of renal nutrition : the official journal of the Council on Renal Nutrition of the National Kidney Foundation 20120301

Protective effects of curcumin, α-lipoic acid, and N-acetylcysteine against carbon tetrachloride-induced liver fibrosis in rats.

Journal of physiology and biochemistry 20120301

Renal ischaemia/reperfusion injury: possible role of aquaporins.

Acta physiologica (Oxford, England) 20120301

Oxidative stress in preretinopathic diabetes subjects and antioxidants.

Diabetes technology & therapeutics 20120301

R-α-lipoic acid does not reverse hepatic inflammation of aging, but lowers lipid anabolism, while accentuating circadian rhythm transcript profiles.

American journal of physiology. Regulatory, integrative and comparative physiology 20120301

Changes in expression profiles of antioxidant enzymes in diabetic rat kidneys.

Diabetes/metabolism research and reviews 20120301

Mitochondrial lipoic acid scavenging is essential for Plasmodium berghei liver stage development.

Cellular microbiology 20120301

Reactive oxygen species are required for the hypothalamic osmoregulatory response.

Endocrinology 20120301

Lipoic acid attenuates high-fat-diet-induced oxidative stress and B-cell-related immune depression.

Nutrition (Burbank, Los Angeles County, Calif.) 20120301

Antiproliferative effects of a new α-lipoic acid derivative, DHL-HisZnNa, in HT29 human colon cancer cells in vitro.

Expert opinion on therapeutic targets 20120301

Combination of alpha lipoic acid and superoxide dismutase leads to physiological and symptomatic improvements in diabetic neuropathy.

Drugs in R&D 20120301

Biogenesis of iron-sulfur clusters in mammalian cells: new insights and relevance to human disease.

Disease models & mechanisms 20120301

[Alpha lipoic acid affect the function of EPCs incubated by high-glucose].

Xi bao yu fen zi mian yi xue za zhi = Chinese journal of cellular and molecular immunology 20120301

Oligomerized lychee fruit extract (OLFE) and a mixture of vitamin C and vitamin E for endurance capacity in a double blind randomized controlled trial.

Journal of clinical biochemistry and nutrition 20120301

Effects of coenzyme Q10 and α-lipoic acid supplementation in fructose fed rats.

Journal of clinical biochemistry and nutrition 20120301

Oxidative stress and benefits of antioxidant agents in acute and chronic hepatitis.

Hepatitis monthly 20120301

Fluorophore targeting to cellular proteins via enzyme-mediated azide ligation and strain-promoted cycloaddition.

Journal of the American Chemical Society 20120227

Poly(ethylene glycol)-based multidentate oligomers for biocompatible semiconductor and gold nanocrystals.

Langmuir : the ACS journal of surfaces and colloids 20120207

Playing with peptides: how to build a supramolecular peptide nanostructure by exploiting helix···helix macrodipole interactions.

Langmuir : the ACS journal of surfaces and colloids 20120207

Adding a combination of hydroxycitrate and lipoic acid (METABLOC™) to chemotherapy improves effectiveness against tumor development: experimental results and case report.

Investigational new drugs 20120201

α-Lipoic acid attenuates vascular calcification via reversal of mitochondrial function and restoration of Gas6/Axl/Akt survival pathway.

Journal of cellular and molecular medicine 20120201

Review of the literature and suggestions for the design of rodent survival studies for the identification of compounds that increase health and life span.

Age (Dordrecht, Netherlands) 20120201

Effects of oxidized cooking oil and α-lipoic acid on blood antioxidants: enzyme activities and lipid peroxidation in rats fed a high-fat diet.

Biological trace element research 20120201

Role of AMP-activated protein kinase in α-lipoic acid-induced vasodilatation in spontaneously hypertensive rats.

American journal of hypertension 20120201

Mixed SAMs and MALDI-ToF MS: preparation of N-glycosylamine derivative and thioctic acid methyl ester bearing 1,2-dithiolane groups and detection of enzymatic reaction on Au.

Bioorganic chemistry 20120201

A comparative assessment of α-lipoic acid N-phenylamides as non-steroidal androgen receptor antagonists both on and off gold nanoparticles.

Bioorganic chemistry 20120201

Dihydrolipoyl dioleoylglycerol antioxidant capacity in phospholipid vesicles.

Chemistry and physics of lipids 20120201

Effect of α-lipoic acid on platelet reactivity in type 1 diabetic patients.

Diabetes care 20120201

The effect of alpha lipoic acid on the developmental competence of mouse isolated preantral follicles.

Journal of assisted reproduction and genetics 20120201

α-Lipoic acid, diabetic neuropathy, and Nathan's prophecy.

Angiology 20120201

Inflammatory cause of metabolic syndrome via brain stress and NF-κB.

Aging 20120201

Modifications of andrographolide to increase some biological activities: a patent review (2006 - 2011).

Expert opinion on therapeutic patents 20120201

Metabolism and regulation of glycerolipids in the yeast Saccharomyces cerevisiae.

Genetics 20120201

Induction of ER Stress-Mediated Apoptosis by α-Lipoic Acid in A549 Cell Lines.

The Korean journal of thoracic and cardiovascular surgery 20120201

Diabetic peripheral neuropathy in type 2 diabetes mellitus in Korea.

Diabetes & metabolism journal 20120201

Five new amicoumacins isolated from a marine-derived bacterium Bacillus subtilis.

Marine drugs 20120201

DNA bimodified gold nanoparticles.

Langmuir : the ACS journal of surfaces and colloids 20120131

Alpha-lipoic acid attenuates methionine choline deficient diet-induced steatohepatitis in C57BL/6 mice.

Life sciences 20120130

Gold nanoparticles as a label-free probe for the detection of amyloidogenic protein.

Talanta 20120130

Bioorganic synthesis, characterization and antioxidant activity of esters of natural phenolics and α-lipoic acid.

Journal of biotechnology 20120120

Diels-Alder cycloaddition for fluorophore targeting to specific proteins inside living cells.

Journal of the American Chemical Society 20120118

Co-administration of apocynin with lipoic acid enhances neuroprotection in a rat model of ischemia/reperfusion.

Neuroscience letters 20120117

Reaction characteristics of andrographolide and its analogue AL-1 with GSH, as a simple chemical simulation of NF-κB inhibition.

Molecules (Basel, Switzerland) 20120112

α-Lipoic acid, a scavenging agent for H₂O₂, reduces ethanol-stimulated locomotion in mice.

Psychopharmacology 20120101

Mitochondrial calcium homeostasis as potential target for mitochondrial medicine.

Mitochondrion 20120101

Proteomic analysis of mitochondria in APOE transgenic mice and in response to an ischemic challenge.

Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 20120101

Effect of lipoic acid on expression of angiogenic factors in diabetic rat retina.

Clinical & experimental ophthalmology 20120101

Taurine reduces nitrosative stress and nitric oxide synthase expression in high glucose-exposed human Schwann cells.

Experimental neurology 20120101

Dietary oxidative stress and antioxidant defense with an emphasis on plant extract administration.

Cell stress & chaperones 20120101

Acetyl-L-carnitine and α-lipoic acid affect rotenone-induced damage in nigral dopaminergic neurons of rat brain, implication for Parkinson's disease therapy.

Pharmacology, biochemistry, and behavior 20120101

Insufficient endogenous redox buffer capacity may underlie neuronal vulnerability to cerebral ischemia and reperfusion.

Journal of neuroscience research 20120101

Reduced expression of lipoic acid synthase accelerates diabetic nephropathy.

Journal of the American Society of Nephrology : JASN 20120101

Evaluation of protective and curative role of α-lipoic acid and selenium in gentamicin-induced nephrotoxicity in rabbits.

Pakistan journal of pharmaceutical sciences 20120101

Betaine treatment attenuates chronic ethanol-induced hepatic steatosis and alterations to the mitochondrial respiratory chain proteome.

International journal of hepatology 20120101

The role of metformin in the management of NAFLD.

Experimental diabetes research 20120101

Sulphur-containing non enzymatic antioxidants: therapeutic tools against cancer.

Frontiers in bioscience (Scholar edition) 20120101

Oxidative Stress and Down Syndrome: A Route toward Alzheimer-Like Dementia.

Current gerontology and geriatrics research 20120101

Efficacy of cosmetic formulations containing dispersion of liposome with magnesium ascorbyl phosphate, alpha-lipoic acid and kinetin.

Photochemistry and photobiology 20120101

Integration of gene-based markers in a pearl millet genetic map for identification of candidate genes underlying drought tolerance quantitative trait loci.

BMC plant biology 20120101

Cellular dysfunction in diabetes as maladaptive response to mitochondrial oxidative stress.

Experimental diabetes research 20120101

Novel Neurovascular Protective Agents: Effects of INV-155, INV-157, INV-159, and INV-161 versus Lipoic Acid and Captopril in a Rat Stroke Model.

Cardiology research and practice 20120101

Activation of TRPV1 by capsaicin induces functional kinin B(1) receptor in rat spinal cord microglia.

Journal of neuroinflammation 20120101

A new model for raf kinase inhibitory protein induced chemotherapeutic resistance.

PloS one 20120101

Adaptation of Salmonella enterica Hadar under static magnetic field: effects on outer membrane protein pattern.

Proteome science 20120101

Environmental determinants of chronic disease and medical approaches: recognition, avoidance, supportive therapy, and detoxification.

Journal of environmental and public health 20120101

Brain insulin resistance and deficiency as therapeutic targets in Alzheimer's disease.

Current Alzheimer research 20120101

Alpha lipoic Acid for symptomatic peripheral neuropathy in patients with diabetes: a meta-analysis of randomized controlled trials.

International journal of endocrinology 20120101

Insight into the transmission biology and species-specific functional capabilities of tsetse (Diptera: glossinidae) obligate symbiont Wigglesworthia.

mBio 20120101

Inhibitory effect of 4-O-methylhonokiol on lipopolysaccharide-induced neuroinflammation, amyloidogenesis and memory impairment via inhibition of nuclear factor-kappaB in vitro and in vivo models.

Journal of neuroinflammation 20120101

Toward a Systemic Understanding of Listeria monocytogenes Metabolism during Infection.

Frontiers in microbiology 20120101

Mechanisms underlying skeletal muscle insulin resistance induced by fatty acids: importance of the mitochondrial function.

Lipids in health and disease 20120101

LAL regulators SCO0877 and SCO7173 as pleiotropic modulators of phosphate starvation response and actinorhodin biosynthesis in Streptomyces coelicolor.

PloS one 20120101

Glycemic and oxidative status of patients with type 2 diabetes mellitus following oral administration of alpha-lipoic acid: a randomized double-blinded placebo-controlled study.

Asia Pacific journal of clinical nutrition 20120101

Antioxidant therapies: a potential role in perinatal medicine.

Neuroendocrinology 20120101

Identifying low pH active and lactate-utilizing taxa within oral microbiome communities from healthy children using stable isotope probing techniques.

PloS one 20120101

Alleviative effects of α-lipoic acid supplementation on acute heat stress-induced thermal panting and the level of plasma nonesterified fatty acids in hypothyroid broiler chickens.

British poultry science 20120101

Antioxidant-induced stress.

International journal of molecular sciences 20120101

Conflict of evidence: carotenoids and other micronutrients in the prevention and treatment of cognitive impairment.

BioFactors (Oxford, England) 20120101

Improvements of insulin resistance in ovariectomized rats by a novel phytoestrogen from Curcuma comosa Roxb.

BMC complementary and alternative medicine 20120101

Glucagon-like peptides 1 and 2 and vasoactive intestinal peptide are neuroprotective on cultured and mast cell co-cultured rat myenteric neurons.

BMC gastroenterology 20120101

Major phenolic compounds, antioxidant capacity and antidiabetic potential of rice bean (Vigna umbellata L.) in China.

International journal of molecular sciences 20120101

Dihydrolipoic acid induces cytotoxicity in mouse blastocysts through apoptosis processes.

International journal of molecular sciences 20120101

Heme oxygenase-1 induction and organic nitrate therapy: beneficial effects on endothelial dysfunction, nitrate tolerance, and vascular oxidative stress.

International journal of hypertension 20120101

A versatile ΦC31 based reporter system for measuring AP-1 and Nrf2 signaling in Drosophila and in tissue culture.

PloS one 20120101

Sulforaphane potentiates RNA damage induced by different xenobiotics.

PloS one 20120101

Role of neural NO synthase (nNOS) uncoupling in the dysfunctional nitrergic vasorelaxation of penile arteries from insulin-resistant obese Zucker rats.

PloS one 20120101

Current view on phytoplasma genomes and encoded metabolism.

TheScientificWorldJournal 20120101

Etiopathogenesis of insulin autoimmunity.

Anatomy research international 20120101

Induction of oxidative stress in kidney.

International journal of nephrology 20120101

Trace elements affect methanogenic activity and diversity in enrichments from subsurface coal bed produced water.

Frontiers in microbiology 20120101

Ca2+/calmodulin-dependent protein kinase kinase is not involved in hypothalamic AMP-activated protein kinase activation by neuroglucopenia.

PloS one 20120101

Improvement of genetic stability in lymphocytes from Fanconi anemia patients through the combined effect of α-lipoic acid and N-acetylcysteine.

Orphanet journal of rare diseases 20120101

Resveratrol-loaded solid lipid nanoparticles versus nanostructured lipid carriers: evaluation of antioxidant potential for dermal applications.

International journal of nanomedicine 20120101

Tackling Chemotherapy-induced Alopecia.

International journal of trichology 20120101

Enhancement of lipid stability of broiler breast meat and meat products fed on alpha lipoic acid and alpha tocopherol acetate supplemented feed.

Lipids in health and disease 20120101

Oxidative stress and heart failure in altered thyroid States.

TheScientificWorldJournal 20120101

The effects of the melatonin treatment on the oxidative stress and apoptosis in diabetic eye and brain.

TheScientificWorldJournal 20120101

A combination of lipoic acid plus coenzyme Q10 induces PGC1α, a master switch of energy metabolism, improves stress response, and increases cellular glutathione levels in cultured C2C12 skeletal muscle cells.

Oxidative medicine and cellular longevity 20120101

Bioactive dietary supplements reactivate ER expression in ER-negative breast cancer cells by active chromatin modifications.

PloS one 20120101

Anti-inflammatory and antinociceptive effects of salbutamol on acute and chronic models of inflammation in rats: involvement of an antioxidant mechanism.

Mediators of inflammation 20120101

Schisandrin B as a hormetic agent for preventing age-related neurodegenerative diseases.

Oxidative medicine and cellular longevity 20120101

Effect of (R)-α-lipoic acid supplementation on serum lipids and antioxidative ability in patients with age-related macular degeneration.

Annals of nutrition & metabolism 20120101

The antioxidant mechanisms underlying the aged garlic extract- and S-allylcysteine-induced protection.

Oxidative medicine and cellular longevity 20120101

Oxidative stress in 5/6 nephrectomized rat model: effect of alpha-lipoic acid.

Renal failure 20120101

Comparative geno-plasticity analysis of Mycoplasma bovis HB0801 (Chinese isolate).

PloS one 20120101

Inhibition of gene expression of organic cation/carnitine transporter and antioxidant enzymes in oxazaphosphorines-induced acute cardiomyopathic rat models.

Oxidative medicine and cellular longevity 20120101

The antioxidant role of xanthurenic acid in the Aedes aegypti midgut during digestion of a blood meal.

PloS one 20120101

Recent advances in the treatment of neurodegenerative diseases based on GSH delivery systems.

Oxidative medicine and cellular longevity 20120101

Antioxidants in kidney diseases: the impact of bardoxolone methyl.

International journal of nephrology 20120101

TGF-β(2)- and H(2)O(2)-induced biological changes in optic nerve head astrocytes are reduced by the antioxidant alpha-lipoic acid.

Ophthalmic research 20120101

Cardiac fibrosis and dysfunction in experimental diabetic cardiomyopathy are ameliorated by alpha-lipoic acid.

Cardiovascular diabetology 20120101

Label-free capacitive DNA sensor using immobilized pyrrolidinyl PNA probe: effect of the length and terminating head group of the blocking thiols.

Biosensors & bioelectronics 20120101

Effect of alpha-lipoic acid on memory, oxidation, and lifespan in SAMP8 mice.

Journal of Alzheimer's disease : JAD 20120101

Effects of heat treatment on structural modification and in vivo antioxidant capacity of soy protein.

Nutrition (Burbank, Los Angeles County, Calif.) 20120101

Assessment of a standardized ROS production profile in humans by electron paramagnetic resonance.

Oxidative medicine and cellular longevity 20120101

Restoration of dioxin-induced damage to fetal steroidogenesis and gonadotropin formation by maternal co-treatment with α-lipoic acid.

PloS one 20120101

L-2-Oxothiazolidine-4-carboxylic acid or α-lipoic acid attenuates airway remodeling: involvement of nuclear factor-κB (NF-κB), nuclear factor erythroid 2p45-related factor-2 (Nrf2), and hypoxia-inducible factor (HIF).

International journal of molecular sciences 20120101

Development of quinoxaline 1, 4-dioxides resistance in Escherichia coli and molecular change under resistance selection.

PloS one 20120101

Alfa-lipoic acid controls tumor growth and modulates hepatic redox state in Ehrlich-ascites-carcinoma-bearing mice.

TheScientificWorldJournal 20120101

Protective effects of glutathione and lipoic acid against cadmium-induced oxidative stress in rat's kidney.

Renal failure 20120101

Uptake of biotin by Chlamydia Spp. through the use of a bacterial transporter (BioY) and a host-cell transporter (SMVT).

PloS one 20120101

Compromised mitochondrial fatty acid synthesis in transgenic mice results in defective protein lipoylation and energy disequilibrium.

PloS one 20120101

Lipoic acid synthetase deficiency causes neonatal-onset epilepsy, defective mitochondrial energy metabolism, and glycine elevation.

American journal of human genetics 20111209

Self-complementary recognition of supramolecular urea-aminotriazines in solution and on surfaces.

Langmuir : the ACS journal of surfaces and colloids 20111206

Lipoic acid modified low molecular weight polyethylenimine mediates nontoxic and highly potent in vitro gene transfection.

Molecular pharmaceutics 20111205

Biodegradable microspheres loaded with an anti-Parkinson prodrug: an in vivo pharmacokinetic study.

Molecular pharmaceutics 20111205

Dietary alpha lipoic acid supplementation prevents synovial inflammation and bone destruction in collagen-induced arthritic mice.

Rheumatology international 20111201

Palladium-α-lipoic acid complex attenuates alloxan-induced hyperglycemia and enhances the declined blood antioxidant status in diabetic rats.

Journal of diabetes 20111201

Intervention of mitochondrial dysfunction-oxidative stress-dependent apoptosis as a possible neuroprotective mechanism of α-lipoic acid against rotenone-induced parkinsonism and L-dopa toxicity.

Neuroscience research 20111201

Neuroprotective and anti-oxidative effects of the hemodialysate actovegin on primary rat neurons in vitro.

Neuromolecular medicine 20111201

α-Lipoic acid (LA) enantiomers protect SH-SY5Y cells against glutathione depletion.

Neurochemistry international 20111201

Direct analysis of carbohydrates in animal plasma by ion chromatography coupled with mass spectrometry and pulsed amperometric detection for use as a non-invasive diagnostic tool.

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20111201

Formation of dopamine quinone-DNA adducts and their potential role in the etiology of Parkinson's disease.

IUBMB life 20111201

Suppression of high pacing-induced ANP secretion by antioxidants in isolated rat atria.

Peptides 20111201

A systematic screen to discover and analyze apicoplast proteins identifies a conserved and essential protein import factor.

PLoS pathogens 20111201

Single dose bioavailability and pharmacokinetic study of a innovative formulation of α-lipoic acid (ALA600) in healthy volunteers.

Minerva medica 20111201

Abstracts of the 6th cachexia conference, milan, Italy, december 8-10, 2011.

Journal of cachexia, sarcopenia and muscle 20111201

Reversibly crosslinked poly(vinyl alcohol) nanoparticles for triggered release of doxorubicin.

Journal of controlled release : official journal of the Controlled Release Society 20111130

Thermosensitive dendrimer formulation for drug delivery at physiologically relevant temperatures.

Chemical communications (Cambridge, England) 20111128

Mutations in the dimer interface of dihydrolipoamide dehydrogenase promote site-specific oxidative damages in yeast and human cells.

The Journal of biological chemistry 20111118

A fatal mitochondrial disease is associated with defective NFU1 function in the maturation of a subset of mitochondrial Fe-S proteins.

American journal of human genetics 20111111

Thioredoxin and dihydrolipoic acid are required for 3-mercaptopyruvate sulfurtransferase to produce hydrogen sulfide.

The Biochemical journal 20111101

Electrophile-modified lipoic derivatives of PDC-E2 elicits anti-mitochondrial antibody reactivity.

Journal of autoimmunity 20111101

Non-redox-active lipoate derivates disrupt cancer cell mitochondrial metabolism and are potent anticancer agents in vivo.

Journal of molecular medicine (Berlin, Germany) 20111101

Mapping the lipoylation site of Arabidopsis thaliana plastidial dihydrolipoamide S-acetyltransferase using mass spectrometry and site-directed mutagenesis.

Plant physiology and biochemistry : PPB 20111101

Alpha-lipoic acid protects against myocardial ischemia/reperfusion injury via multiple target effects.

Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20111101

Lipoic acid attenuates innate immune infiltration and activation in the visceral adipose tissue of obese insulin resistant mice.

Lipids 20111101

Exploiting the lipoic acid structure in the search for novel multitarget ligands against Alzheimer's disease.

European journal of medicinal chemistry 20111101

Role of mitochondria biogenesis in the metabolic memory associated with the continued progression of diabetic retinopathy and its regulation by lipoic acid.

Investigative ophthalmology & visual science 20111101

Dihydrolipoyl histidinate zinc complex, a new antioxidant, attenuates hepatic ischemia-reperfusion injury in rats.

Journal of gastroenterology and hepatology 20111101

Multitarget-directed ligands: innovative chemical probes and therapeutic tools against Alzheimer's disease.

Current topics in medicinal chemistry 20111101

Metabolic correction in the management of diabetic peripheral neuropathy: improving clinical results beyond symptom control.

Current clinical pharmacology 20111101

Dietary açai modulates ROS production by neutrophils and gene expression of liver antioxidant enzymes in rats.

Journal of clinical biochemistry and nutrition 20111101

Antioxidant composition causes antiexsudorific effect in the model of chronic venous insufficiency.

Bulletin of experimental biology and medicine 20111101

Protective effect of acetyl-l-carnitine and α-lipoic acid against the acute toxicity of diepoxybutane to human lymphocytes.

Toxicology 20111028

Signaling of hypochlorous acid by selective deprotection of dithiane. [corrected].

Organic & biomolecular chemistry 20111021

Oxidative damage compromises energy metabolism in the axonal degeneration mouse model of X-adrenoleukodystrophy.

Antioxidants & redox signaling 20111015

A simple, label-free AuNPs-based colorimetric ultrasensitive detection of nerve agents and highly toxic organophosphate pesticide.

Biosensors & bioelectronics 20111015

Insulin resistance due to nutrient excess: is it a consequence of AMPK downregulation?

Cell cycle (Georgetown, Tex.) 20111015

Mutations in iron-sulfur cluster scaffold genes NFU1 and BOLA3 cause a fatal deficiency of multiple respiratory chain and 2-oxoacid dehydrogenase enzymes.

American journal of human genetics 20111007

The effect of uremic toxin cyanate (OCN–) on anaerobic sulfur metabolism and prooxidative processes in the rat kidney: a protective role of lipoate.

Human & experimental toxicology 20111001

Short-term oral α-lipoic acid does not prevent lipid-induced dysregulation of glucose homeostasis in obese and overweight nondiabetic men.

American journal of physiology. Endocrinology and metabolism 20111001

Abrogation of cisplatin-induced nephrotoxicity in mice by alpha lipoic acid through ameliorating oxidative stress and enhancing gene expression of antioxidant enzymes.

European journal of pharmacology 20111001

Full-spectrum antioxidant therapy featuring astaxanthin coupled with lipoprivic strategies and salsalate for management of non-alcoholic fatty liver disease.

Medical hypotheses 20111001

Effects of a new synthetic butyrylcholinesterase inhibitor, HBU-39, on cell proliferation and neuroblast differentiation in the hippocampal dentate gyrus in a scopolamine-induced amnesia animal model.

Neurochemistry international 20111001

CD55 deficiency protects against atherosclerosis in ApoE-deficient mice via C3a modulation of lipid metabolism.

The American journal of pathology 20111001

Design, synthesis and evaluation of PEGylated lipoic acid derivatives with functionality as potent anti-melanogenic agents.

European journal of medicinal chemistry 20111001

Selective responses of myenteric neurons to oxidative stress and diabetic stimuli.

Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society 20111001

Reversible human serum albumin binding of lipocrine: a circular dichroism study.

Chirality 20111001

Impact of α-lipoic acid on liver peroxisome proliferator-activated receptor-α, vascular remodeling, and oxidative stress in insulin-resistant rats.

Canadian journal of physiology and pharmacology 20111001

Lipoic acid and moderate swimming improves the estrous cycle and oxidative stress in Wistar rats.

Applied physiology, nutrition, and metabolism = Physiologie appliquee, nutrition et metabolisme 20111001

Flavonoids: not just for cancer anymore.

Compendium (Yardley, PA) 20111001

Prevention of free fatty acid-induced hepatic lipotoxicity by carnitine via reversal of mitochondrial dysfunction.

Liver international : official journal of the International Association for the Study of the Liver 20111001

[The influence of lipoic acid on total protein concentration in the liver and spleen tissue in rats during lipopolysaccharide-induced oxidative stress].

Polski merkuriusz lekarski : organ Polskiego Towarzystwa Lekarskiego 20111001

Effects of α-lipoic acid and L-carnosine supplementation on antioxidant activities and lipid profiles in rats.

Nutrition research and practice 20111001

A novel piezoelectric immunosensor for the detection of malarial Plasmodium falciparum histidine rich protein-2 antigen.

Talanta 20110930

Structure-guided engineering of a Pacific Blue fluorophore ligase for specific protein imaging in living cells.

Biochemistry 20110927

Protection against genotoxic damages following whole body gamma radiation exposure in mice by lipoic acid.

Mutation research 20110918

Ibuprofen and lipoic acid codrug 1 control Alzheimer's disease progression by down-regulating protein kinase C ε-mediated metalloproteinase 2 and 9 levels in β-amyloid infused Alzheimer's disease rat model.

Brain research 20110915

A complex lipoate utilization pathway in Listeria monocytogenes.

The Journal of biological chemistry 20110909

Oxidative stress and the etiology of insulin resistance and type 2 diabetes.

Free radical biology & medicine 20110901

Does laryngopharyngeal reflux cause intraoral burning sensations? A preliminary study.

European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery 20110901

Effects of lipoic acid on apelin in 3T3-L1 adipocytes and in high-fat fed rats.

Journal of physiology and biochemistry 20110901

Reciprocal effects of α-lipoic acid on adenosine monophosphate-activated protein kinase activity in obesity induced by ovariectomy in rats.

Menopause (New York, N.Y.) 20110901

The effect of antioxidants on the response of the rabbit urinary bladder to in vitro ischemia/reperfusion.

Molecular and cellular biochemistry 20110901

Immunomodulatory effect of DL-α-lipoic acid in aged rats.

Experimental gerontology 20110901

Chemoprotection of lipoic acid against microcystin-induced toxicosis in common carp (Cyprinus carpio, Cyprinidae).

Comparative biochemistry and physiology. Toxicology & pharmacology : CBP 20110901

A translational continuum of model systems for evaluating treatment strategies in Alzheimer's disease: isradipine as a candidate drug.

Disease models & mechanisms 20110901

Efficacy and safety of antioxidant treatment with α-lipoic acid over 4 years in diabetic polyneuropathy: the NATHAN 1 trial.

Diabetes care 20110901

Insulin autoimmune syndrome induced by α-lipoic acid in a Caucasian woman: case report.

Diabetes care 20110901

Nutrition delivery for obese ICU patients: delivery issues, lack of guidelines, and missed opportunities.

JPEN. Journal of parenteral and enteral nutrition 20110901

Allopurinol reduces the lethality associated with acute renal failure induced by Crotalus durissus terrificus snake venom: comparison with probenecid.

PLoS neglected tropical diseases 20110901

[Role of lipoic acid in health and disease].

Polski merkuriusz lekarski : organ Polskiego Towarzystwa Lekarskiego 20110901

Beneficial effects of alpha lipoic acid on cerulein-induced experimental acute pancreatitis in rats.

Ulusal travma ve acil cerrahi dergisi = Turkish journal of trauma & emergency surgery : TJTES 20110901

Lipoic acid alters amino acid neurotransmitters content in rat hippocampus after pilocarpine-induced seizures.

Fundamental & clinical pharmacology 20110801

Combination of alpha lipoic acid and gabapentin, its efficacy in the treatment of Burning Mouth Syndrome: a randomized, double-blind, placebo controlled trial.

Medicina oral, patologia oral y cirugia bucal 20110801

The organellar genome and metabolic potential of the hydrogen-producing mitochondrion of Nyctotherus ovalis.

Molecular biology and evolution 20110801

α-Lipoic acid normalizes nociceptive neuronal activity at the spinal cord of diabetic rats.

Diabetes, obesity & metabolism 20110801

Surface-engineered quantum dots for the labeling of hydrophobic microdomains in bacterial biofilms.

Biomaterials 20110801

1,3-Dinitrobenzene-induced metabolic impairment through selective inactivation of the pyruvate dehydrogenase complex.

Toxicological sciences : an official journal of the Society of Toxicology 20110801

Quantification and morphometry of myenteric neurones in the jejunum of Holtzman rats (Rattus norvegicus).

Anatomia, histologia, embryologia 20110801

Amelioration of lipid abnormalities by α-lipoic acid through antioxidative and anti-inflammatory effects.

Obesity (Silver Spring, Md.) 20110801

Nutritional approaches to modulate oxidative stress in Alzheimer's disease.

Current Alzheimer research 20110801

Stable dye-labelled oligonucleotide-nanoparticle conjugates for nucleic acid detection.

Nanoscale 20110801

Photochemical stability of lipoic acid and its impact on skin ageing.

Free radical research 20110801

Down syndrome and dementia: a randomized, controlled trial of antioxidant supplementation.

American journal of medical genetics. Part A 20110801

Role of mercury toxicity in hypertension, cardiovascular disease, and stroke.

Journal of clinical hypertension (Greenwich, Conn.) 20110801

Nanoencapsulation improves the in vitro antioxidant activity of lipoic acid.

Journal of biomedical nanotechnology 20110801

Chemical rescue of malaria parasites lacking an apicoplast defines organelle function in blood-stage Plasmodium falciparum.

PLoS biology 20110801

Continuous-flow reactor-based synthesis of carbohydrate and dihydrolipoic acid-capped quantum dots.

Nature protocols 20110728

Multifunctional surface modification of gold-stabilized nanoparticles by bioorthogonal reactions.

Journal of the American Chemical Society 20110727

Effects of lipoic acid, caffeic acid and a synthesized lipoyl-caffeic conjugate on human hepatoma cell lines.

Molecules (Basel, Switzerland) 20110727

Single-molecule colocalization studies shed light on the idea of fully emitting versus dark single quantum dots.

Small (Weinheim an der Bergstrasse, Germany) 20110718

Arsenic-induced oxidative stress and its reversibility.

Free radical biology & medicine 20110715

A deficit in zinc availability can cause alterations in tubulin thiol redox status in cultured neurons and in the developing fetal rat brain.

Free radical biology & medicine 20110715

Electrochemical analysis of HIV-1 reverse transcriptase serum level: exploiting protein binding to a functionalized nanostructured surface.

Talanta 20110715

Identification of N-propylnoraporphin-11-yl 5-(1,2-dithiolan-3-yl)pentanoate as a new anti-Parkinson's agent possessing a dopamine D2 and serotonin 5-HT1A dual-agonist profile.

Journal of medicinal chemistry 20110714

Lipid stability and antioxidant profile of microsomal fraction of broiler meat enriched with α-lipoic acid and α-tocopherol acetate.

Journal of agricultural and food chemistry 20110713

Lipoic acid stimulates cAMP production via G protein-coupled receptor-dependent and -independent mechanisms.

The Journal of nutritional biochemistry 20110701

Lipoic acid inhibits leptin secretion and Sp1 activity in adipocytes.

Molecular nutrition & food research 20110701

The effect of the uremic toxin cyanate (CNO⁻) on anaerobic cysteine metabolism and oxidative processes in the rat liver: a protective effect of lipoate.

Toxicology mechanisms and methods 20110701

Synthesis and biological evaluations of novel apocynin analogues.

European journal of medicinal chemistry 20110701

Suppression of the later stages of radiation-induced carcinogenesis by antioxidant dietary formulations.

Radiation research 20110701

Bacterial cysteine desulfurases: versatile key players in biosynthetic pathways of sulfur-containing biofactors.

Applied microbiology and biotechnology 20110701

Selective binding of carbamate pesticides by self-assembled monolayers of calix[4]arene lipoic acid: wettability and impedance dual-signal response.

Organic letters 20110701

Thioctic acid-induced acute cholestatic hepatitis.

The Annals of pharmacotherapy 20110701

Antioxidants halt axonal degeneration in a mouse model of X-adrenoleukodystrophy.

Annals of neurology 20110701

The search for reliable biomarkers of disease in multiple chemical sensitivity and other environmental intolerances.

International journal of environmental research and public health 20110701

Salt-mediated self-assembly of thioctic acid on gold nanoparticles.

ACS nano 20110628

Multifunctional compact zwitterionic ligands for preparing robust biocompatible semiconductor quantum dots and gold nanoparticles.

Journal of the American Chemical Society 20110622

Linking of sensor molecules with amino groups to amino-functionalized AFM tips.

Bioconjugate chemistry 20110615

Simultaneous determination of lipoic acid (LA) and dihydrolipoic acid (DHLA) in human plasma using high-performance liquid chromatography coupled with electrochemical detection.

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20110615

Neuropharmacological effects of lipoic acid and ubiquinone on the mRNA level of interleukin-1β and acetylcholinesterase activity in rat hippocampus after seizures.

Fundamental & clinical pharmacology 20110601

Effect of alpha lipoic acid on cardiac autonomic dysfunction and platelet reactivity in type 1 diabetes: rationale and design of the AUTOnomic function and platelet REACTivity trial (AUTO-REACT protocol).

Diabetes research and clinical practice 20110601

The proglycation effect of caffeic acid leads to the elevation of oxidative stress and inflammation in monocytes, macrophages and vascular endothelial cells.

The Journal of nutritional biochemistry 20110601

Antioxidant supplementation reduces skeletal muscle mitochondrial biogenesis.

Medicine and science in sports and exercise 20110601

Role of obesity-associated dysfunctional adipose tissue in cancer: a molecular nutrition approach.

Biochimica et biophysica acta 20110601

Testicular oxidative damage and role of combined antioxidant supplementation in experimental diabetic rats.

Journal of physiology and biochemistry 20110601

An antioxidant screening assay based on oxidant-induced growth arrest in Saccharomyces cerevisiae.

FEMS yeast research 20110601

Suppression of growth and invasive behavior of human prostate cancer cells by ProstaCaid™: mechanism of activity.

International journal of oncology 20110601

Glycine cleavage enzyme complex: molecular cloning and expression of the H-protein cDNA from cultured human skin fibroblasts.

Biochemistry and cell biology = Biochimie et biologie cellulaire 20110601

Alpha-lipoic acid inhibits endoplasmic reticulum stress-induced cell death through PI3K/Akt signaling pathway in FRTL5 thyroid cells.

Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme 20110601

Effect of alpha-lipoic acid on blood glucose, insulin resistance and glutathione peroxidase of type 2 diabetic patients.

Saudi medical journal 20110601

Loss of taste responds to high-dose biotin treatment.

Journal of the American College of Nutrition 20110601

Environmental pathways to autoimmune diseases: the cases of primary biliary cirrhosis and multiple sclerosis.

Archives of medical science : AMS 20110601

A new strategy improves assembly efficiency of DNA mono-modified gold nanoparticles.

Chemical communications (Cambridge, England) 20110528

Preparation and characterization of poly(lactic-co-glycolic acid) microspheres loaded with a labile antiparkinson prodrug.

International journal of pharmaceutics 20110516

Photoswitchable rotaxanes on gold nanoparticles.

Organic & biomolecular chemistry 20110507

Effects of combination tocopherols and alpha lipoic acid therapy on oxidative stress and inflammatory biomarkers in chronic kidney disease.

Journal of renal nutrition : the official journal of the Council on Renal Nutrition of the National Kidney Foundation 20110501

Essential role of ERK activation in neurite outgrowth induced by α-lipoic acid.

Biochimica et biophysica acta 20110501

The effects of lipoic acid and α-tocopherol supplementation on the lipid profile and insulin sensitivity of patients with type 2 diabetes mellitus: a randomized, double-blind, placebo-controlled trial.

Diabetes research and clinical practice 20110501

Analysis of the efficacy, safety, and regulatory status of novel forms of creatine.

Amino acids 20110501

The creatine kinase system and pleiotropic effects of creatine.

Amino acids 20110501

The α-lipoic acid derivative sodium zinc dihydrolipoylhistidinate reduces chemotherapy-induced alopecia in a rat model: a pilot study.

Surgery today 20110501

Evolving coronary stents coated with new bioactive agents.

Korean circulation journal 20110501

Effect of a dual drug-coated stent with abciximab and alpha-lipoic Acid in a porcine coronary restenosis model.

Korean circulation journal 20110501

Lipoic acid ameliorates arsenic trioxide-induced HO-1 expression and oxidative stress in THP-1 monocytes and macrophages.

Chemico-biological interactions 20110425

Proflavine derivatives as fluorescent imaging agents of amyloid deposits.

Bioorganic & medicinal chemistry letters 20110415

Synthesis and biological evaluation of 3,7-diazabicyclo[4.3.0]nonan-8-ones as potential nootropic and analgesic drugs.

Journal of medicinal chemistry 20110414

Inhibitory effect of α-lipoic acid on platelet aggregation is mediated by PPARs.

Journal of agricultural and food chemistry 20110413

Effects of lipoic acid on antiapoptotic genes in control and ethanol-treated fetal rhombencephalic neurons.

Brain research 20110406

Hybrid lipoic acid derivatives to attack prion disease on multiple fronts.

ChemMedChem 20110404

Neuropharmacological effects of lipoic acid and ubiquinone on δ-aminolevulinic dehydratase, Na(+) , K(+) -ATPase, and Mg(2+) -ATPase activities in rat hippocampus after pilocarpine-induced seizures.

Fundamental & clinical pharmacology 20110401

Metabolic manipulators: a well founded strategy to combat mitochondrial dysfunction.

Journal of inherited metabolic disease 20110401

Antipsychotic-induced DRD2 upregulation and its prevention by α-lipoic acid in SH-SY5Y neuroblastoma cells.

Synapse (New York, N.Y.) 20110401

Age-related oxidative decline of mitochondrial functions in rat brain is prevented by long term oral antioxidant supplementation.

Biogerontology 20110401

Self-medication of migraine and tension-type headache: summary of the evidence-based recommendations of the Deutsche Migräne und Kopfschmerzgesellschaft (DMKG), the Deutsche Gesellschaft für Neurologie (DGN), the Österreichische Kopfschmerzgesellschaft (ÖKSG) and the Schweizerische Kopfwehgesellschaft (SKG).

The journal of headache and pain 20110401

Cellular mechanisms by which lipoic acid confers protection during the early stages of cerebral ischemia: a possible role for calcium.

Neuroscience research 20110401

Lipoic acid decreases inflammation and confers neuroprotection in experimental autoimmune optic neuritis.

Journal of neuroimmunology 20110401

α-lipoic acid can improve endothelial dysfunction in subjects with impaired fasting glucose.

Metabolism: clinical and experimental 20110401

Nutritional supplements and their effect on glucose control.

Current diabetes reports 20110401

A novel two-gene requirement for the octanoyltransfer reaction of Bacillus subtilis lipoic acid biosynthesis.

Molecular microbiology 20110401

A novel amidotransferase required for lipoic acid cofactor assembly in Bacillus subtilis.

Molecular microbiology 20110401

Epigenetic changes in mitochondrial superoxide dismutase in the retina and the development of diabetic retinopathy.

Diabetes 20110401

Lipoic acid increases the expression of genes involved in bone formation in mice fed a high-fat diet.

Nutrition research (New York, N.Y.) 20110401

[Extract of Ginkgo biloba and alpha-lipoic acid attenuate advanced glycation end products accumulation and RAGE expression in diabetic nephropathy rats].

Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine 20110401

α-Lipoic acid inhibits liver fibrosis through the attenuation of ROS-triggered signaling in hepatic stellate cells activated by PDGF and TGF-β.

Toxicology 20110328

Substrate and inhibitor specificities differ between human cytosolic and mitochondrial thioredoxin reductases: Implications for development of specific inhibitors.

Free radical biology & medicine 20110315

Protein-protein interactions in assembly of lipoic acid on the 2-oxoacid dehydrogenases of aerobic metabolism.

The Journal of biological chemistry 20110311

Carbonic anhydrase activators: gold nanoparticles coated with derivatized histamine, histidine, and carnosine show enhanced activatory effects on several mammalian isoforms.

Journal of medicinal chemistry 20110310

Differential effects of coenzyme Q10 and α-lipoic acid on two models of in vitro oxidative damage to the rabbit urinary bladder.

International urology and nephrology 20110301

Protective, antioxidative and antiapoptotic effects of 2-methoxy-6-acetyl-7-methyljuglone from Polygonum cuspidatum in PC12 cells.

Planta medica 20110301

Evidence that α-lipoic acid inhibits NF-κB activation independent of its antioxidant function.

Inflammation research : official journal of the European Histamine Research Society ... [et al.] 20110301

A combination of melatonin and alpha lipoic acid has greater cardioprotective effect than either of them singly against cadmium-induced oxidative damage.

Cardiovascular toxicology 20110301

Lipoamide or lipoic acid stimulates mitochondrial biogenesis in 3T3-L1 adipocytes via the endothelial NO synthase-cGMP-protein kinase G signalling pathway.

British journal of pharmacology 20110301

Mitochondrial optic neuropathies - disease mechanisms and therapeutic strategies.

Progress in retinal and eye research 20110301

Protective role of exogenous α-lipoic acid (ALA) on hippocampal antioxidant status and memory function in rat pups exposed to sodium arsenite during the early post-natal period.

Toxicology mechanisms and methods 20110301

New lipoic acid derivative drug sodium zinc dihydrolipoylhistidinate prevents cardiac dysfunction in an isolated perfused rat heart model.

Critical care medicine 20110301

Mitochondrion-specific antioxidants as drug treatments for Alzheimer disease.

CNS & neurological disorders drug targets 20110301

Antioxidants in the treatment of diabetes.

Current diabetes reviews 20110301

The effects of thrombin and cytokines upon the biomechanics and remodeling of isolated amnion membrane, in vitro.

Placenta 20110301

Effects of intragastric fructose and dextrose on mesenteric microvascular inflammation and postprandial hyperemia in the rat.

JPEN. Journal of parenteral and enteral nutrition 20110301

Antioxidative effects of N-acetylcysteine, lipoic acid, taurine, and curcumin in the muscle of Cyprinus carpio L. exposed to cadmium.

Arhiv za higijenu rada i toksikologiju 20110301

Alleviation of lindane induced toxicity in testis of Swiss mice (Mus musculus) by combined treatment with vitamin C, vitamin E and alpha-lipoic acid.

Indian journal of experimental biology 20110301

[The effect of oral alpha-lipoic acid in overweight/obese individuals on brachial-ankle pulse wave velocity and supine blood pressure: a randomized, crossover, double-blind, placebo-controlled trial].

Zhonghua liu xing bing xue za zhi = Zhonghua liuxingbingxue zazhi 20110301

Metabolite cross-feeding enhances virulence in a model polymicrobial infection.

PLoS pathogens 20110301

Utilization of adjuvant arthritis model for evaluation of new approaches in rheumatoid arthritis therapy focused on regulation of immune processes and oxidative stress.

Interdisciplinary toxicology 20110301

The new pyridoindole antioxidant SMe1EC2 and its intervention in hypoxia/hypoglycemia-induced impairment of longterm potentiation in rat hippocampus.

Interdisciplinary toxicology 20110301

Lipoic acid protects against reperfusion injury in the early stages of cerebral ischemia.

Brain research 20110223

Towards an early diagnosis of HIV infection: an electrochemical approach for detection of HIV-1 reverse transcriptase enzyme.

The Analyst 20110221

Microwave-assisted functionalization of carbon nanohorns via [2+1] nitrenes cycloaddition.

Chemical communications (Cambridge, England) 20110207

Chronic pretreatment with acetyl-L-carnitine and ±DL-α-lipoic acid protects against acute glutamate-induced neurotoxicity in rat brain by altering mitochondrial function.

Neurotoxicity research 20110201

Dyslipidemic high-fat diet affects adversely bone metabolism in mice associated with impaired antioxidant capacity.

Nutrition (Burbank, Los Angeles County, Calif.) 20110201

Degradation of 4-n-nonylphenol under nitrate reducing conditions.

Biodegradation 20110201

Colonic motor dysfunction in human diabetes is associated with enteric neuronal loss and increased oxidative stress.

Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society 20110201

The role of lipid peroxidation products and oxidative stress in activation of the canonical wingless-type MMTV integration site (WNT) pathway in a rat model of diabetic retinopathy.

Diabetologia 20110201

The contributions of antioxidant activity of lipoic acid in reducing neurogenerative progression of Parkinson's disease: a review.

The International journal of neuroscience 20110201

α-Lipoic acid suppresses the development of DNFB-induced atopic dermatitis-like symptoms in NC/Nga mice.

Experimental dermatology 20110201

Synthesis and effects of some novel tetrahydronaphthalene derivatives on proliferation and nitric oxide production in lipopolysaccharide activated Raw 264.7 macrophages.

European journal of medicinal chemistry 20110201

Alpha-lipoic acid rebalances redox and immune-testicular milieu in septic rats.

Chemico-biological interactions 20110201

Oxidative stress: key player in gastrointestinal complications of diabetes.

Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society 20110201

Participation of hindbrain AMP-activated protein kinase in glucoprivic feeding.

Diabetes 20110201

Protection of flunarizine on cerebral mitochondria injury induced by cortical spreading depression under hypoxic conditions.

The journal of headache and pain 20110201

Protective role of lipoic acid on methotrexate induced intestinal damage in rabbit model.

Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology 20110201

Water-soluble semiconductor nanocrystals cap exchanged with metalated ligands.

ACS nano 20110125

Cisplatin-induced cardiotoxicity: Mechanisms and cardioprotective strategies.

European journal of pharmacology 20110110

Surprising substrate versatility in SLC5A6: Na+-coupled I- transport by the human Na+/multivitamin transporter (hSMVT).

The Journal of biological chemistry 20110107

Theories and management of aging: modern and ayurveda perspectives.

Evidence-based complementary and alternative medicine : eCAM 20110101

Assessment of the Antioxidant and Reactive Oxygen Species Scavenging Activity of Methanolic Extract of Caesalpinia crista Leaf.

Evidence-based complementary and alternative medicine : eCAM 20110101

The Role of Th17 in Neuroimmune Disorders: Target for CAM Therapy. Part II.

Evidence-based complementary and alternative medicine : eCAM 20110101

Inhibition of inflammatory gene expression in keratinocytes using a composition containing carnitine, thioctic Acid and saw palmetto extract.

Evidence-based complementary and alternative medicine : eCAM 20110101

Role of lipoic acid on insulin resistance and leptin in experimentally diabetic rats.

Journal of diabetes and its complications 20110101

Alpha-lipoic acid protects against potassium cyanide-induced seizures and mortality.

Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie 20110101

α-Lipoic acid protects diabetic apolipoprotein E-deficient mice from nephropathy.

Journal of diabetes and its complications 20110101

Effects of selenite and chelating agents on mammalian thioredoxin reductase inhibited by mercury: implications for treatment of mercury poisoning.

FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20110101

(R)-α-Lipoic acid treatment restores ceramide balance in aging rat cardiac mitochondria.

Pharmacological research 20110101

Inhibition of aldehyde dehydrogenase 2 by oxidative stress is associated with cardiac dysfunction in diabetic rats.

Molecular medicine (Cambridge, Mass.) 20110101

Modulatory effects of lipoic acid and selenium against cadmium-induced biochemical alterations in testicular steroidogenesis.

Journal of biochemical and molecular toxicology 20110101

Identification of clinically used drugs that activate pregnane X receptors.

Drug metabolism and disposition: the biological fate of chemicals 20110101

The autoimmunity of primary biliary cirrhosis and the clonal selection theory.

Immunology and cell biology 20110101

α-Lipoic acid ameliorates foam cell formation via liver X receptor α-dependent upregulation of ATP-binding cassette transporters A1 and G1.

Free radical biology & medicine 20110101

Lipoic acid inhibits caspase-dependent and -independent cell death pathways and is neuroprotective against hippocampal damage after pilocarpine-induced seizures.

Pharmacology, biochemistry, and behavior 20110101

α-Lipoic acid has anti-inflammatory and anti-oxidative properties: an experimental study in rats with carrageenan-induced acute and cotton pellet-induced chronic inflammations.

The British journal of nutrition 20110101

Differential efficiency of simvastatin and lipoic acid treatments on Bothrops jararaca envenomation-induced acute kidney injury in mice.

Toxicon : official journal of the International Society on Toxinology 20110101

α-Ketoglutarate dehydrogenase: a mitochondrial redox sensor.

Free radical research 20110101

Synthesis of a novel ester of hydroxytyrosol and α-lipoic acid exhibiting an antiproliferative effect on human colon cancer HT-29 cells.

European journal of medicinal chemistry 20110101

Anti-oxidative effect of lipoic Acid in spinal cord ischemia/reperfusion.

Medical principles and practice : international journal of the Kuwait University, Health Science Centre 20110101

Effects of alpha-lipoic Acid on body weight in obese subjects.

The American journal of medicine 20110101

Is dental amalgam safe for humans? The opinion of the scientific committee of the European Commission.

Journal of occupational medicine and toxicology (London, England) 20110101

Immunomodulation of Autoimmune Arthritis by Herbal CAM.

Evidence-based complementary and alternative medicine : eCAM 20110101

Effects of lipoic acid on proliferation and apoptosis of liver cells in rats with metabolic stress.

Bulletin of experimental biology and medicine 20110101

Effect of pro- and antioxidants on insulin sensitivity and glucose tolerance.

Bulletin of experimental biology and medicine 20110101

What was lost in translation in the DHA trial is whom you should intend to treat.

Alzheimer's research & therapy 20110101

Protective effect of α-lipoic acid against arsenic trioxide-induced acute cardiac toxicity in rats.

Journal of pharmacological sciences 20110101

Lipoic acid: energy metabolism and redox regulation of transcription and cell signaling.

Journal of clinical biochemistry and nutrition 20110101

Integrative identification of Arabidopsis mitochondrial proteome and its function exploitation through protein interaction network.

PloS one 20110101

Metabolic reconstruction of the archaeon methanogen Methanosarcina Acetivorans.

BMC systems biology 20110101

Effects of rasagiline, its metabolite aminoindan and selegiline on glutamate receptor mediated signalling in the rat hippocampus slice in vitro.

BMC pharmacology 20110101

The biochemical and cellular basis for nutraceutical strategies to attenuate neurodegeneration in Parkinson's disease.

International journal of molecular sciences 20110101

Identification of surface proteins in Enterococcus faecalis V583.

BMC genomics 20110101

Conjugated Quantum Dots Inhibit the Amyloid β (1-42) Fibrillation Process.

International journal of Alzheimer's disease 20110101

[Tiolepta (thioctic acid) in the treatment of vibration disease].

Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova 20110101

A Regenerative Antioxidant Protocol of Vitamin E and α-Lipoic Acid Ameliorates Cardiovascular and Metabolic Changes in Fructose-Fed Rats.

Evidence-based complementary and alternative medicine : eCAM 20110101

Critical update for the clinical use of L-carnitine analogs in cardiometabolic disorders.

Vascular health and risk management 20110101

The aqueous solubility and thermal stability of α-lipoic acid are enhanced by cyclodextrin.

Bioscience, biotechnology, and biochemistry 20110101

[Neuroprotective effects of lipoic acid and superoxide dismutase in the rat model of cerebral ischemia].

Rossiiskii fiziologicheskii zhurnal imeni I.M. Sechenova 20110101

A study of toxicity and differential gene expression in murine liver following exposure to anti-malarial drugs: amodiaquine and sulphadoxine-pyrimethamine.

Malaria journal 20110101

Alpha lipoic acid treatment improved endothelium-dependent relaxation in diabetic rat aorta.

Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 20110101

Oxidative stress in dog with heart failure: the role of dietary Fatty acids and antioxidants.

Veterinary medicine international 20110101

Mitochondrial approaches to protect against cardiac ischemia and reperfusion injury.

Frontiers in physiology 20110101

Postmyocardial infarct remodeling and heart failure: potential contributions from pro- and antiaging factors.

Cardiology research and practice 20110101

Ozone acting on human blood yields a hormetic dose-response relationship.

Journal of translational medicine 20110101

Reversing brain damage in former NFL players: implications for traumatic brain injury and substance abuse rehabilitation.

Journal of psychoactive drugs 20110101

Lipoic acid effects on glutamate and taurine concentrations in rat hippocampus after pilocarpine-induced seizures.

Arquivos de neuro-psiquiatria 20110101

A current evaluation of the safety of angiotensin receptor blockers and direct renin inhibitors.

Vascular health and risk management 20110101

Nutritional and metabolic status of children with autism vs. neurotypical children, and the association with autism severity.

Nutrition & metabolism 20110101

Antioxidant and antinociceptive effects of Citrus limon essential oil in mice.

Journal of biomedicine & biotechnology 20110101

Volatile constituents, inorganic elements and primary screening of bioactivity of black coral cigarette holders.

Marine drugs 20110101

Targeted metabolomic analyses of cellular models of pelizaeus-merzbacher disease reveal plasmalogen and myo-inositol solute carrier dysfunction.

Lipids in health and disease 20110101

Antioxidant properties of aminoethylcysteine ketimine decarboxylated dimer: a review.

International journal of molecular sciences 20110101

One universal common endpoint in mouse models of amyotrophic lateral sclerosis.

PloS one 20110101

Molecular strategy for survival at a critical high temperature in Eschierichia coli.

PloS one 20110101

Elemental profiling of single bacterial cells as a function of copper exposure and growth phase.

PloS one 20110101

Global transcriptome response in Lactobacillus sakei during growth on ribose.

BMC microbiology 20110101

Modulation of the Chlamydia trachomatis in vitro transcriptome response by the sex hormones estradiol and progesterone.

BMC microbiology 20110101

Neuroprotective effects of alpha lipoic Acid on haloperidol-induced oxidative stress in the rat brain.

Cell & bioscience 20110101

Effect of fruit and vegetable concentrates on endothelial function in metabolic syndrome: a randomized controlled trial.

Nutrition journal 20110101

Biopsy-Proven Acute Tubular Necrosis due to Vancomycin Toxicity.

International journal of nephrology 20110101

Metabolic myopathy presenting with polyarteritis nodosa: a case report.

Journal of medical case reports 20110101

Heterofucan from Sargassum filipendula induces apoptosis in HeLa cells.

Marine drugs 20110101

The complete genome sequence of Mycoplasma bovis strain Hubei-1.

PloS one 20110101

Plasmodium falciparum glutamate dehydrogenase a is dispensable and not a drug target during erythrocytic development.

Malaria journal 20110101

Association between genetic variants in the Coenzyme Q10 metabolism and Coenzyme Q10 status in humans.

BMC research notes 20110101

Protective effect of liposome-encapsulated glutathione in a human epidermal model exposed to a mustard gas analog.

Journal of toxicology 20110101

Haptenation: chemical reactivity and protein binding.

Journal of allergy 20110101

[Decrease in tumorigenic activity of murine hepatoma cells after treatment with antioxidants and melatonin].

Tsitologiia 20110101

Antioxidants and the integrity of ocular tissues.

Veterinary medicine international 20110101

Regulation of Inducible Nitric Oxide Synthase (iNOS) and its Potential Role in Insulin Resistance, Diabetes and Heart Failure.

The open cardiovascular medicine journal 20110101

Optimal therapeutic strategy for treating patients with hypertension and atherosclerosis: focus on olmesartan medoxomil.

Vascular health and risk management 20110101

The effect of alpha-lipoic acid in the prevention of peritoneal adhesions.

The Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology 20110101

The effects of omega-3 Fatty acids on matrix metalloproteinase-9 production and cell migration in human immune cells: implications for multiple sclerosis.

Autoimmune diseases 20110101

[Cerebroprotective effect of 3-oxypyridine and succinic acid derivatives in acute phase of alloxan-induced diabetes mellitus in rats].

Eksperimental'naia i klinicheskaia farmakologiia 20110101

Vitamin A has anti-oligomerization effects on amyloid-β in vitro.

Journal of Alzheimer's disease : JAD 20110101

Alpha-lipoic acid for the prevention of diabetic macular edema.

Ophthalmologica. Journal international d'ophtalmologie. International journal of ophthalmology. Zeitschrift fur Augenheilkunde 20110101

Effect of glycine on lead mobilization, lead-induced oxidative stress, and hepatic toxicity in rats.

Journal of toxicology 20110101

Comparison of antioxidant effectiveness of lipoic acid and dihydrolipoic acid.

Journal of biochemical and molecular toxicology 20110101

Antioxidant therapy: current status and future prospects.

Current medicinal chemistry 20110101

Animal models of calcific aortic valve disease.

International journal of inflammation 20110101

Effect of weight reduction on cardiovascular risk factors and CD34-positive cells in circulation.

International journal of medical sciences 20110101

Lifespan-extending effects of royal jelly and its related substances on the nematode Caenorhabditis elegans.

PloS one 20110101

[Influence of alpha-lipoic acid on liver glutathione system of healthy and Ehrlich ascites carcinoma transplanted mice].

Biomeditsinskaia khimiia 20110101

Enhanced antihypertensive activity of candesartan cilexetil nanosuspension: formulation, characterization and pharmacodynamic study.

Scientia pharmaceutica 20110101

Update on the management of diabetic polyneuropathies.

Diabetes, metabolic syndrome and obesity : targets and therapy 20110101

Hydroxyl radical and its scavengers in health and disease.

Oxidative medicine and cellular longevity 20110101

[Oxidative homeostasis and functional parameters of rats at high altitudes with alpha-lipoic acid correction].

Aviakosmicheskaia i ekologicheskaia meditsina = Aerospace and environmental medicine 20110101

Two functionally distinctive phosphopantetheinyl transferases from amoeba Dictyostelium discoideum.

PloS one 20110101

Genome of Mycoplasma haemofelis, unraveling its strategies for survival and persistence.

Veterinary research 20110101

Amyloid beta protein-induced zinc sequestration leads to synaptic loss via dysregulation of the ProSAP2/Shank3 scaffold.

Molecular neurodegeneration 20110101

Critical appraisal of the use of alpha lipoic acid (thioctic acid) in the treatment of symptomatic diabetic polyneuropathy.

Therapeutics and clinical risk management 20110101

Detailed kinetics and regulation of mammalian 2-oxoglutarate dehydrogenase.

BMC biochemistry 20110101

Long-term use and tolerability of irbesartan for control of hypertension.

Integrated blood pressure control 20110101

Novel Conjugates of 1,3-Diacylglycerol and Lipoic Acid: Synthesis, DPPH Assay, and RP-LC-MS-APCI Analysis.

Journal of lipids 20110101

Vitamin A palmitate and α-lipoic acid stability in o/w emulsions for cosmetic application.

Journal of cosmetic science 20110101

No immune responses by the expression of the yeast Ndi1 protein in rats.

PloS one 20110101

Lipoic acid - biological activity and therapeutic potential.

Pharmacological reports : PR 20110101

In vitro and in vivo plasmalogen replacement evaluations in rhizomelic chrondrodysplasia punctata and Pelizaeus-Merzbacher disease using PPI-1011, an ether lipid plasmalogen precursor.

Lipids in health and disease 20110101

Different impacts of cardiovascular risk factors on oxidative stress.

International journal of molecular sciences 20110101

Cardioprotective effect of ascorbic acid on doxorubicin-induced myocardial toxicity in rats.

Indian journal of pharmacology 20110101

Amelioration of nitrobenzene-induced nephrotoxicity by the ethanol extract of the herb Euphorbia hirta.

Pharmacognosy research 20110101

Combined effects of p-coumaric acid and naringenin against doxorubicin-induced cardiotoxicity in rats.

Pharmacognosy research 20110101

Paromomycin affects translation and vesicle-mediated trafficking as revealed by proteomics of paromomycin -susceptible -resistant Leishmania donovani.

PloS one 20110101

Clinical symptoms in fibromyalgia are better associated to lipid peroxidation levels in blood mononuclear cells rather than in plasma.

PloS one 20110101

Pharmaceutical and nutraceutical effects of Pinus pinaster bark extract.

Research in pharmaceutical sciences 20110101

Combined treatment with antioxidants and immunosuppressants on cytokine release by human peripheral blood mononuclear cells - chemically injured keratocyte reaction.

Molecular vision 20110101

Influence of mercury exposure on blood pressure, resting heart rate and heart rate variability in French Polynesians: a cross-sectional study.

Environmental health : a global access science source 20110101

Fatty acids and gene expression responses to bioactive compounds in Atlantic salmon (Salmo salar L.) hepatocytes.

Neuro endocrinology letters 20110101

Effect of α-lipoic acid and exercise training on cardiovascular disease risk in obesity with impaired glucose tolerance.

Lipids in health and disease 20110101

Anisotropic nanomaterials: structure, growth, assembly, and functions.

Nano reviews 20110101

Diabetes and alpha lipoic Acid.

Frontiers in pharmacology 20110101

Transplantation of bone marrow-derived mononuclear cells improves mechanical hyperalgesia, cold allodynia and nerve function in diabetic neuropathy.

PloS one 20110101

Biomedical exploitation of chitin and chitosan via mechano-chemical disassembly, electrospinning, dissolution in imidazolium ionic liquids, and supercritical drying.

Marine drugs 20110101

Potential Therapeutic Roles for Inhibition of the PI3K/Akt/mTOR Pathway in the Pathophysiology of Diabetic Retinopathy.

Journal of ophthalmology 20110101

Elucidation of the dual role of Mycobacterial MoeZR in molybdenum cofactor biosynthesis and cysteine biosynthesis.

PloS one 20110101

Oral bioavailability of the ether lipid plasmalogen precursor, PPI-1011, in the rabbit: a new therapeutic strategy for Alzheimer's disease.

Lipids in health and disease 20110101

Effect of a vitamin/mineral supplement on children and adults with autism.

BMC pediatrics 20110101

Protective effect of α-lipoic acid on oxidized low density lipoprotein-induced human umbilical vein endothelial cell injury.

Pharmacological reports : PR 20110101

The effects of alpha lipoic acid on cerebral vasospasm following experimental subarachnoid hemorrhage in the rabbit.

Turkish neurosurgery 20110101

Protein profile changes during porcine oocyte aging and effects of caffeine on protein expression patterns.

PloS one 20110101

Oxaliplatin-induced neuropathy in colorectal cancer.

Journal of oncology 20110101

Early peroxisome proliferator-activated receptor gamma regulated genes involved in expansion of pancreatic beta cell mass.

BMC medical genomics 20110101

Overview of stabilizing ligands for biocompatible quantum dot nanocrystals.

Sensors (Basel, Switzerland) 20110101

Dietary lipoic acid influences antioxidant capability and oxidative status of broilers.

International journal of molecular sciences 20110101

Advances in carcinogenic metal toxicity and potential molecular markers.

International journal of molecular sciences 20110101

[Comparative study of alpha-lipoic acid and mexidol effects on affective status, cognitive functions and quality of life in diabetes mellitus patients].

Eksperimental'naia i klinicheskaia farmakologiia 20110101

Simple HPLC evaluation of lipoamidase activity in tissue using a newly synthesized fluorescent substrate, dansyl-α-lipoyllysine.

Journal of nutritional science and vitaminology 20110101

Epigenetic Contributions to the Relationship between Cancer and Dietary Intake of Nutrients, Bioactive Food Components, and Environmental Toxicants.

Frontiers in genetics 20110101

[Antihypoxic effect of 3-hydroxypyridine and succinic acid derivatives and their nootropic action in alloxan diabetes].

Eksperimental'naia i klinicheskaia farmakologiia 20110101

[A search for new markers of oxidative stress in brain ischemia for the optimization of treatment approaches].

Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova 20110101

[Thioctic (alpha-lipoic) acid-spectrum of clinical use].

Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova 20110101

Strategies for the discovery of anti-aging compounds.

Expert opinion on drug discovery 20110101

[Application of alpha-lipoic acid in clinical practice].

Likars'ka sprava 20110101

Is endothelial dysfunction of cerebral small vessel responsible for white matter lesions after chronic cerebral hypoperfusion in rats?

Journal of the neurological sciences 20101215

Reverse-phase liquid chromatographic determination of α-lipoic acid in dietary supplements using a boron-doped diamond electrode.

Journal of chromatography. A 20101203

Alpha-lipoic acid does not alter stress protein response to acute exercise in diabetic brain.

Cell biochemistry and function 20101202

Effects of oxidized cooking oil and α-lipoic acid on liver antioxidants: enzyme activities and lipid peroxidation in rats fed a high fat diet.

Biological trace element research 20101201

Is it time to reassess alpha lipoic acid and niacinamide therapy in schizophrenia?

Medical hypotheses 20101201

Metals, oxidative stress and neurodegenerative disorders.

Molecular and cellular biochemistry 20101201

Emerging drugs for diabetic neuropathy.

Expert opinion on emerging drugs 20101201

Alpha-lipoic acid modulates GFAP, vimentin, nestin, cyclin D1 and MAP-kinase expression in astroglial cell cultures.

Neurochemical research 20101201

How to obtain labeled proteins and what to do with them.

Current opinion in biotechnology 20101201

Compartmentation of redox metabolism in malaria parasites.

PLoS pathogens 20101201

D-galactose effectiveness in modeling aging and therapeutic antioxidant treatment in mice.

Rejuvenation research 20101201

[Effects of α-lipoic acid and vitamin C on oxidative stress in rat exposed to chronic arsenic toxicity].

Zhonghua lao dong wei sheng zhi ye bing za zhi = Zhonghua laodong weisheng zhiyebing zazhi = Chinese journal of industrial hygiene and occupational diseases 20101201

Lipoic acid suppresses compound 48/80-induced anaphylaxis-like reaction.

Anatomy & cell biology 20101201

Quantitative PCR tissue expression profiling of the human SGLT2 gene and related family members.

Diabetes therapy : research, treatment and education of diabetes and related disorders 20101201

The role of oxidative stress and effect of alpha-lipoic acid in reexpansion pulmonary edema - an experimental study.

Archives of medical science : AMS 20101201

Lipoic acid synthesis: a new family of octanoyltransferases generally annotated as lipoate protein ligases.

Biochemistry 20101123

Prevention of diabetic nephropathy in Ins2(+/)⁻(AkitaJ) mice by the mitochondria-targeted therapy MitoQ.

The Biochemical journal 20101115

Neuroprotective role of lipoic acid against acute toxicity of N-acetylaspartic acid.

Molecular and cellular biochemistry 20101101

The construction, fouling and enzymatic cleaning of a textile dye surface.

Journal of colloid and interface science 20101101

Hypothalamic Angptl4/Fiaf is a novel regulator of food intake and body weight.

Diabetes 20101101

α-Lipoic acid prevents neointimal hyperplasia via induction of p38 mitogen-activated protein kinase/Nur77-mediated apoptosis of vascular smooth muscle cells and accelerates postinjury reendothelialization.

Arteriosclerosis, thrombosis, and vascular biology 20101101

Towards a unifying, systems biology understanding of large-scale cellular death and destruction caused by poorly liganded iron: Parkinson's, Huntington's, Alzheimer's, prions, bactericides, chemical toxicology and others as examples.

Archives of toxicology 20101101

Effect of antioxidants on mitochondrial function in HIV-1-related lipoatrophy: a pilot study.

AIDS research and human retroviruses 20101101

Pharmacokinetics of orally administered DL-α-lipoic acid in dogs.

American journal of veterinary research 20101101

Arabidopsis β-ketoacyl-[acyl carrier protein] synthase i is crucial for fatty acid synthesis and plays a role in chloroplast division and embryo development.

The Plant cell 20101101

Structure Effect on Antioxidant Activity of Catecholamines toward Singlet Oxygen and Other Reactive Oxygen Species in vitro.

Journal of clinical biochemistry and nutrition 20101101

[Biochemical changes in cavernosal tissue caused by single sided cavernosal nerve resection and the effects of alpha lipoic acid on these changes].

Actas urologicas espanolas 20101101

The CD14(+/low)CD16(+) monocyte subset is more susceptible to spontaneous and oxidant-induced apoptosis than the CD14(+)CD16(-) subset.

Cell death & disease 20101101

The DOCA-Salt Hypertensive Rat as a Model of Cardiovascular Oxidative and Inflammatory Stress.

Current cardiology reviews 20101101

Lipid rafts and redox regulation of cellular signaling in cholesterol induced atherosclerosis.

Current cardiology reviews 20101101

Development of biocompatible SERS nanotag with increased stability by chemisorption of reporter molecule for in vivo cancer detection.

Biosensors & bioelectronics 20101015

A mimic of the pyruvate dehydrogenase complex.

Bioorganic & medicinal chemistry letters 20101015

Determination of lipoic acid in human plasma by HPLC-ECD using liquid-liquid and solid-phase extraction: Method development, validation and optimization of experimental parameters.

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20101015

Impedimetric biosensor for the assessment of the clotting activity of rennet.

Analytical chemistry 20101015

Aging and antioxidants modulate rat brain levels of homocysteine and dehydroepiandrosterone sulphate (DHEA-S): implications in the pathogenesis of Alzheimer's disease.

Neuroscience letters 20101011

Alpha-lipoic acid improves endothelial dysfunction in patients with subclinical hypothyroidism.

Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association 20101001

Evaluation of anti-oxidant treatments in an in vitro model of alkaptonuric ochronosis.

Rheumatology (Oxford, England) 20101001

α-Lipoic acid induces collagen biosynthesis involving prolyl hydroxylase expression via activation of TGF-β-Smad signaling in human dermal fibroblasts.

Connective tissue research 20101001

Evaluation of protective effects of the alpha lipoic acid after spinal cord injury: an animal study.

Injury 20101001

Redox regulatory mechanism of transnitrosylation by thioredoxin.

Molecular & cellular proteomics : MCP 20101001

Perioperative metabolic therapy improves redox status and outcomes in cardiac surgery patients: a randomised trial.

Heart, lung & circulation 20101001

Hypothalamic AMP-activated protein kinase regulates glucose production.

Diabetes 20101001

Downregulation of AMPK accompanies leucine- and glucose-induced increases in protein synthesis and insulin resistance in rat skeletal muscle.

Diabetes 20101001

Alpha-lipoic acid inhibits thrombin-induced fetal membrane weakening in vitro.

Placenta 20101001

Pharmacokinetics of lipoyl vildagliptin, a novel dipeptidyl peptidase IV inhibitor after oral administration in rats.

Xenobiotica; the fate of foreign compounds in biological systems 20101001

Diabetic neuropathies: update on definitions, diagnostic criteria, estimation of severity, and treatments.

Diabetes care 20101001

Comparative effects of α lipoic acid and melatonin on cisplatin-induced neurotoxicity.

The International journal of neuroscience 20101001

Neuroprotective effects of alpha-lipoic acid in experimental spinal cord injury in rats.

The journal of spinal cord medicine 20101001

Role of pyruvate dehydrogenase kinase 4 in regulation of blood glucose levels.

Korean diabetes journal 20101001

Effect of pentoxifylline and/or alpha lipoic acid on experimentally induced acute pancreatitis.

European journal of pharmacology 20100925

[Efficacy and safety of high-dose α-lipoic acid in the treatment of diabetic polyneuropathy].

Zhonghua yi xue za zhi 20100921

Augmentation of cholinesterases and ATPase activities in the cerebellum and pons-medulla oblongata, by a combination of antioxidants (resveratrol, ascorbic acid, alpha-lipoic acid and vitamin E), in acutely lindane intoxicated mice.

Journal of the neurological sciences 20100915

Natural therapeutic magnesium lithospermate B potently protects the endothelium from hyperglycaemia-induced dysfunction.

Cardiovascular research 20100901

Lipoic acid effects on renal function, aminopeptidase activities and oxidative stress in Crotalus durissus terrificus envenomation in mice.

Toxicon : official journal of the International Society on Toxinology 20100901

Anti-apoptotic and neuroprotective effects of α-lipoic acid on spinal cord ischemia-reperfusion injury in rabbits.

Acta neurochirurgica 20100901

The natural antioxidant alpha-lipoic acid induces p27(Kip1)-dependent cell cycle arrest and apoptosis in MCF-7 human breast cancer cells.

European journal of pharmacology 20100901

Blood-to-retina transport of biotin via Na+-dependent multivitamin transporter (SMVT) at the inner blood-retinal barrier.

Experimental eye research 20100901

Oxidative stimuli-responsive nanoprodrug of camptothecin kills glioblastoma cells.

Bioorganic & medicinal chemistry letters 20100901

Different therapeutic strategies for burning mouth syndrome: preliminary data.

Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology 20100901

Last days in the old radiation laboratory (ORL), Berkeley, California, 1954.

Photosynthesis research 20100901

Alzheimer's disease: the pros and cons of pharmaceutical, nutritional, botanical, and stimulatory therapies, with a discussion of treatment strategies from the perspective of patients and practitioners.

Alternative medicine review : a journal of clinical therapeutic 20100901

Neurotoxins: free radical mechanisms and melatonin protection.

Current neuropharmacology 20100901

Effects of DHLA-capped CdSe/ZnS quantum dots on the fibrillation of human serum albumin.

The journal of physical chemistry. B 20100826

Antiplatelet activity of alpha-lipoic acid.

Journal of agricultural and food chemistry 20100811

Alpha-lipoic acid activates dimethylarginine dimethylaminohydrolase in cultured endothelial cells.

Biochemical and biophysical research communications 20100806

Practical prevention of cardiac remodeling and atrial fibrillation with full-spectrum antioxidant therapy and ancillary strategies.

Medical hypotheses 20100801

Amino-functionalized single-chain bolalipids: synthesis and aggregation behavior of new basic building blocks.

Biophysical chemistry 20100801

Natural antioxidants and hypertension: promise and challenges.

Cardiovascular therapeutics 20100801

Improved functionality of antibody-colloidal gold conjugates with the aid of lipoamide-grafted N-[tris(hydroxymethyl)methyl]acrylamide polymers.

Journal of colloid and interface science 20100801

Development of head organizer of the mouse embryo depends on a high level of mitochondrial metabolism.

Developmental biology 20100801

Study of alpha-lipoic acid penetration in the human aqueous after topical administration.

Clinical & experimental ophthalmology 20100801

A stable and controllable Prussian blue layer electrodeposited on self-assembled monolayers for constructing highly sensitive glucose biosensor.

The Analyst 20100801

Reducing agents induce thrombomodulin shedding in human endothelial cells.

Thrombosis research 20100801

Nutraceuticals in diabetes and metabolic syndrome.

Cardiovascular therapeutics 20100801

Radioprotection by alpha-lipoic acid palladium complex formulation (POLY-MVA) in mice.

Cancer biotherapy & radiopharmaceuticals 20100801

Protective roles of alpha-lipoic acid in rat model of mitochondrial DNA4834bp deletion in inner ear.

Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban 20100801

Vascular oxidative stress and inflammation increase with age: ameliorating effects of alpha-lipoic acid supplementation.

Annals of the New York Academy of Sciences 20100801

Lipoic acid increases glutathione peroxidase, Na+, K+-ATPase and acetylcholinesterase activities in rat hippocampus after pilocarpine-induced seizures?

Arquivos de neuro-psiquiatria 20100801

Lipoic acid nanoparticles: effect of polymeric stabilizer on appetite suppression.

Die Pharmazie 20100801

[Complex approach to the treatment of the diskal hernia of lumbosacral spine].

Voenno-meditsinskii zhurnal 20100801

Inhibition of TXNIP expression in vivo blocks early pathologies of diabetic retinopathy.

Cell death & disease 20100801

Multidentate poly(ethylene glycol) ligands provide colloidal stability to semiconductor and metallic nanocrystals in extreme conditions.

Journal of the American Chemical Society 20100721

Tunable and reversible aggregation of poly(ethylene oxide-st-propylene oxide) grafted gold nanoparticles.

Langmuir : the ACS journal of surfaces and colloids 20100720

Sensitive and visual detection of sequence-specific DNA-binding protein via a gold nanoparticle-based colorimetric biosensor.

Analytical chemistry 20100715

alpha-Lipoic acid increases energy expenditure by enhancing adenosine monophosphate-activated protein kinase-peroxisome proliferator-activated receptor-gamma coactivator-1alpha signaling in the skeletal muscle of aged mice.

Metabolism: clinical and experimental 20100701

Lipoic acid and redox status in barley plants subjected to salinity and elevated CO2.

Physiologia plantarum 20100701

Infusion fluids contain harmful glucose degradation products.

Intensive care medicine 20100701

Effect of POLY-MVA, a palladium alpha-lipoic acid complex formulation against declined mitochondrial antioxidant status in the myocardium of aged rats.

Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20100701

Role of oxidative stress and nitric oxide in the protective effects of alpha-lipoic acid and aminoguanidine against isoniazid-rifampicin-induced hepatotoxicity in rats.

Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20100701

Protective effect of lipoic acid against methotrexate-induced oxidative stress in liver mitochondria.

Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20100701

alpha-Lipoic acid alters post-translational modifications and protects the chaperone activity of lens alpha-crystallin in naphthalene-induced cataract.

Current eye research 20100701

HIV gp41 engages gC1qR on CD4+ T cells to induce the expression of an NK ligand through the PIP3/H2O2 pathway.

PLoS pathogens 20100701

A forward-genetic screen and dynamic analysis of lambda phage host-dependencies reveals an extensive interaction network and a new anti-viral strategy.

PLoS genetics 20100701

Multiple molecular mechanisms cause reproductive isolation between three yeast species.

PLoS biology 20100701

Chelation in metal intoxication.

International journal of environmental research and public health 20100701

Lipoic acid effects on monoaminergic system after pilocarpine-induced seizures.

Neuroscience letters 20100625

[Pathomechanism of diabetic neuropathy: background of the pathogenesis-oriented therapy].

Orvosi hetilap 20100613

Crystal structure of aminomethyltransferase in complex with dihydrolipoyl-H-protein of the glycine cleavage system: implications for recognition of lipoyl protein substrate, disease-related mutations, and reaction mechanism.

The Journal of biological chemistry 20100611

Inflammation and apoptosis in aortic tissues of aged type II diabetes: amelioration with alpha-lipoic acid through phosphatidylinositol 3-kinase/Akt- dependent mechanism.

Life sciences 20100605

Prooxidative effects of green tea polyphenol (-)-epigallocatechin-3-gallate on the HIT-T15 pancreatic beta cell line.

Cell biology and toxicology 20100601

Potential utility of full-spectrum antioxidant therapy, citrulline, and dietary nitrate in the management of sickle cell disease.

Medical hypotheses 20100601

Electrical behavior of stored erythrocytes after exposure to gamma radiation and the role of alpha-lipoic acid as radioprotector.

Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine 20100601

BALB/c 3T3 cell transformation assay for the prediction of carcinogenic potential of chemicals and environmental mixtures.

Toxicology in vitro : an international journal published in association with BIBRA 20100601

Reactive oxygen species serve as signals mediating glucose-stimulated somatostatin secretion from cultured rat gastric primary D-cells.

Free radical research 20100601

Why pleiotropic interventions are needed for Alzheimer's disease.

Molecular neurobiology 20100601

Multi-tasking with single platform dendrimers for targeting sub-cellular microenvironments.

Chemistry (Weinheim an der Bergstrasse, Germany) 20100601

Inhibition of lindane-induced toxicity using alpha-lipoic acid and vitamin E in the brain of Mus musculus.

Protoplasma 20100601

A case of diabetic neuropathy combined with Guillain-Barre syndrome.

The Korean journal of internal medicine 20100601

Gene expression patterns of dengue virus-infected children from nicaragua reveal a distinct signature of increased metabolism.

PLoS neglected tropical diseases 20100601

Lack of Association between Glutathione S-Transferase-M1, -T1, and -P1 Polymorphisms and Olanzapine-Induced Weight Gain in Korean Schizophrenic Patients.

Psychiatry investigation 20100601

The effects of lipoic acid on soybean beta-conglycinin-induced anaphylactic reactions in a rat model.

Archives of animal nutrition 20100601

Acute exercise and thioredoxin-1 in rat brain, and alpha-lipoic acid and thioredoxin-interacting protein response, in diabetes.

International journal of sport nutrition and exercise metabolism 20100601

Alterations on monoamines concentration in rat hippocampus produced by lipoic acid.

Arquivos de neuro-psiquiatria 20100601

Neuroprotective strategies in drug abuse-evoked encephalopathy.

Annals of the New York Academy of Sciences 20100601

alpha-Lipoic acid reduces matrix metalloproteinase activity in MDA-MB-231 human breast cancer cells.

Nutrition research (New York, N.Y.) 20100601

Solution structure and characterisation of the human pyruvate dehydrogenase complex core assembly.

Journal of molecular biology 20100528

Lipoic acid prevents oxidative stress in vitro and in vivo by an acute hyperphenylalaninemia chemically-induced in rat brain.

Journal of the neurological sciences 20100515

Synthesis and anticancer evaluation of alpha-lipoic acid derivatives.

Bioorganic & medicinal chemistry letters 20100515

Alpha-lipoic acid as a potential target for the treatment of lung injury caused by cecal ligation and puncture-induced sepsis model in rats.

Shock (Augusta, Ga.) 20100501

Dietary fructose accelerates the development of diabetes in UCD-T2DM rats: amelioration by the antioxidant, alpha-lipoic acid.

American journal of physiology. Regulatory, integrative and comparative physiology 20100501

Downregulation of adipose glutathione S-transferase A4 leads to increased protein carbonylation, oxidative stress, and mitochondrial dysfunction.

Diabetes 20100501

Sulforaphane and alpha-lipoic acid upregulate the expression of the pi class of glutathione S-transferase through c-jun and Nrf2 activation.

The Journal of nutrition 20100501

A combination of alpha lipoic acid and calcium hydroxycitrate is efficient against mouse cancer models: preliminary results.

Oncology reports 20100501

Methylenedioxymethamphetamine inhibits mitochondrial complex I activity in mice: a possible mechanism underlying neurotoxicity.

British journal of pharmacology 20100501

Complementary and alternative medicine for the treatment of multiple sclerosis.

Expert review of clinical immunology 20100501

Protective effects of irbesartan and alpha lipoic acid in STZ-induced diabetic nephropathy in rats.

Renal failure 20100501

Managing diabetic peripheral neuropathic pain in primary care.

The Journal of family practice 20100501

Lipoic acid: an immunomodulator that attenuates glycinin-induced anaphylactic reactions in a rat model.

Journal of agricultural and food chemistry 20100428

Vitamin E as a novel enhancer of macroautophagy in rat hepatocytes and H4-II-E cells.

Biochemical and biophysical research communications 20100416

Small and stable sulfobetaine zwitterionic quantum dots for functional live-cell imaging.

Journal of the American Chemical Society 20100407

Synthesis of an achiral isomer of lipoic acid as an anchor group for SAM formation on gold surfaces.

The Journal of organic chemistry 20100402

Lipoic acid alters delta-aminolevulinic dehydratase, glutathione peroxidase and Na+,K+-ATPase activities and glutathione-reduced levels in rat hippocampus after pilocarpine-induced seizures.

Cellular and molecular neurobiology 20100401

Fructose, but not dextrose, induces leukocyte adherence to the mesenteric venule of the rat by oxidative stress.

Pediatric research 20100401

The prostacyclin analog beraprost sodium ameliorates characteristics of metabolic syndrome in obese Zucker (fatty) rats.

Diabetes 20100401

A new method for the detection and characterization of alpha-lipoic acid mixed disulphides.

Free radical research 20100401

Pharmacokinetic study of lipoic acid in multiple sclerosis: comparing mice and human pharmacokinetic parameters.

Multiple sclerosis (Houndmills, Basingstoke, England) 20100401

Genomic structure of an economically important cyanobacterium, Arthrospira (Spirulina) platensis NIES-39.

DNA research : an international journal for rapid publication of reports on genes and genomes 20100401

Antioxidant diet supplementation starting 24 hours after exposure reduces radiation lethality.

Radiation research 20100401

Banting Lecture 2009: An unfinished journey: molecular pathogenesis to prevention of type 1A diabetes.

Diabetes 20100401

Esmond E. Snell--the pathfinder of B vitamins and cofactors.

Journal of biochemistry 20100401

A target-based high throughput screen yields Trypanosoma brucei hexokinase small molecule inhibitors with antiparasitic activity.

PLoS neglected tropical diseases 20100401

Radioprotectors and mitigators of radiation-induced normal tissue injury.

The oncologist 20100401

Alpha lipoic acid: a new treatment for neuropathic pain in patients with diabetes?

The Netherlands journal of medicine 20100401

[Effects of alpha lipoic acid on hypothalamus-pituitary-adrenal axis in rats].

Nan fang yi ke da xue xue bao = Journal of Southern Medical University 20100401

The Association between Serum GGT Concentration and Diabetic Peripheral Polyneuropathy in Type 2 Diabetic Patients.

Korean diabetes journal 20100401

Global conformational change associated with the two-step reaction catalyzed by Escherichia coli lipoate-protein ligase A.

The Journal of biological chemistry 20100326

Lipoic acid glyco-conjugates, a new class of agents for controlling nonspecific adsorption of blood serum at biointerfaces for biosensor and biomedical applications.

Langmuir : the ACS journal of surfaces and colloids 20100316

Mutated glutathione S-transferase in combination with reduced glutathione shows a synergistic effect in ameliorating oxidative stress and airway inflammation.

Free radical biology & medicine 20100315

The evolution, metabolism and functions of the apicoplast.

Philosophical transactions of the Royal Society of London. Series B, Biological sciences 20100312

Alpha-lipoic acid inhibits hepatic PAI-1 expression and fibrosis by inhibiting the TGF-beta signaling pathway.

Biochemical and biophysical research communications 20100312

Triazaspirodimethoxybenzoyls as selective inhibitors of mycobacterial lipoamide dehydrogenase .

Biochemistry 20100302

Dietary supplement polypharmacy: an unrecognized public health problem?

Evidence-based complementary and alternative medicine : eCAM 20100301

Alpha lipoic acid alleviates oxidative stress and preserves blood brain permeability in rats with subarachnoid hemorrhage.

Neurochemical research 20100301

Effect of antioxidants on airway smooth muscle contraction: action of lipoic acid and some of its novel derivatives on guinea pig tracheal smooth muscle.

Inflammation research : official journal of the European Histamine Research Society ... [et al.] 20100301

The involvement of lipid peroxide-derived aldehydes in aluminum toxicity of tobacco roots.

Plant physiology 20100301

Lipoic acid blocks seizures induced by pilocarpine via increases in delta-aminolevulinic dehydratase and Na+, K+-ATPase activity in rat brain.

Pharmacology, biochemistry, and behavior 20100301

Effect of endogenous and synthetic antioxidants on hydrogen peroxide-induced guinea-pig colon contraction.

Inflammation research : official journal of the European Histamine Research Society ... [et al.] 20100301

The combination of exercise training and alpha-lipoic acid treatment has therapeutic effects on the pathogenic phenotypes of Alzheimer's disease in NSE/APPsw-transgenic mice.

International journal of molecular medicine 20100301

Ibuprofen and lipoic acid diamides as potential codrugs with neuroprotective activity.

Archiv der Pharmazie 20100301

Common tongue conditions in primary care.

American family physician 20100301

Assessment and management of fatigue in neuromuscular disease.

The American journal of hospice & palliative care 20100301

Dietary supplements reduce the cataractogenic potential of proton and HZE-particle radiation in mice.

Radiation research 20100301

Effects of controlled-release alpha lipoic acid in lean, nondiabetic patients with polycystic ovary syndrome.

Journal of diabetes science and technology 20100301

Neuropathy in a rat model of mild diabetes induced by multiple low doses of streptozotocin: effects of the antioxidant stobadine in comparison with a high-dose alpha-lipoic acid treatment.

General physiology and biophysics 20100301

['Hyperglycaemic memory' in human umbilical vein endothelial cells mediated by interacting loop of protein kinase Cbeta(2)-reactive oxygen species].

Zhonghua nei ke za zhi 20100301

Past, present and future therapeutics for cerebellar ataxias.

Current neuropharmacology 20100301

Alpha-lipoic acid regulates heme oxygenase gene expression and nuclear Nrf2 activation as a mechanism of protection against arsenic exposure in HepG2 cells.

Environmental toxicology and pharmacology 20100301

Polyvalent display and packing of peptides and proteins on semiconductor quantum dots: predicted versus experimental results.

Small (Weinheim an der Bergstrasse, Germany) 20100222

Homocysteine-lowering therapy or antioxidant therapy for bone loss in Parkinson's disease.

Movement disorders : official journal of the Movement Disorder Society 20100215

A sensitive LC/MS/MS bioanalysis assay of orally administered lipoic acid in rat blood and brain tissue.

Journal of pharmaceutical and biomedical analysis 20100205

Prevention of high-fat diet-induced muscular lipid accumulation in rats by alpha lipoic acid is not mediated by AMPK activation.

Journal of lipid research 20100201

Thioctic acid protects against carrageenan-induced acute inflammation in rats by reduction in oxidative stress, downregulation of COX-2 mRNA and enhancement of IL-10 mRNA.

Fundamental & clinical pharmacology 20100201

Exercise-induced brachial artery vasodilation: effects of antioxidants and exercise training in elderly men.

American journal of physiology. Heart and circulatory physiology 20100201

Alpha-lipoic acid improves vascular endothelial function in patients with type 2 diabetes: a placebo-controlled randomized trial.

European journal of clinical investigation 20100201

[Importance of the nuclear factor kappaB for the primary open angle glaucoma--a hypothesis].

Klinische Monatsblatter fur Augenheilkunde 20100201

Nutrition and the brain.

Clinics in geriatric medicine 20100201

Pathological, biochemical and haematological investigations on the protective effect of alpha-lipoic acid in experimental aflatoxin toxicosis in chicks.

British poultry science 20100201

[Effect of alpha-lipoic acid on hearing functions after cerebral concussion].

Zhonghua er bi yan hou tou jing wai ke za zhi = Chinese journal of otorhinolaryngology head and neck surgery 20100201

Ameliorative effect of a combination of vitamin E, vitamin C, alpha-lipoic acid and stilbene resveratrol on lindane induced toxicity in mice olfactory lobe and cerebrum.

Indian journal of experimental biology 20100201

Antioxidant properties and neuroprotective capacity of strawberry tree fruit (Arbutus unedo).

Nutrients 20100201

Electrochemistry of ferrocenoyl beta-peptide monolayers on gold.

Langmuir : the ACS journal of surfaces and colloids 20100119

Large meta-analysis of multiple cancers reveals a common, compact and highly prognostic hypoxia metagene.

British journal of cancer 20100119

Lipoic acid effects on established atherosclerosis.

Life sciences 20100116

Antioxidants rescue photoreceptors in rd1 mice: Relationship with thiol metabolism.

Free radical biology & medicine 20100115

Mitochondrial DNA haplogroups influence the therapeutic response to riboflavin in migraineurs.

Neurology 20100112

[Treatment of neuropathies].

Orvosi hetilap 20100110

Intervention of alpha-lipoic acid ameliorates methotrexate-induced oxidative stress and genotoxicity: A study in rat intestine.

Chemico-biological interactions 20100105

Differential regulation of Apak by various DNA damage signals.

Molecular and cellular biochemistry 20100101

Lipoic Acid increases hippocampal choline acetyltransferase and acetylcholinesterase activities and improvement memory in epileptic rats.

Neurochemical research 20100101

Mitochondrial fatty acid synthesis--an adopted set of enzymes making a pathway of major importance for the cellular metabolism.

Progress in lipid research 20100101

ACS67, a hydrogen sulfide-releasing derivative of latanoprost acid, attenuates retinal ischemia and oxidative stress to RGC-5 cells in culture.

Investigative ophthalmology & visual science 20100101

Effects of lipoic acid on oxidative stress in rat striatum after pilocarpine-induced seizures.

Neurochemistry international 20100101

The use of mitochondrial nutrients to improve the outcome of infertility treatment in older patients.

Fertility and sterility 20100101

The role of zinc in the modulation of neuronal proliferation and apoptosis.

Neurotoxicity research 20100101

Oxidative stress and gamma radiation-induced cancellous bone loss with musculoskeletal disuse.

Journal of applied physiology (Bethesda, Md. : 1985) 20100101

Alpha-lipoic acid prevents bupivacaine-induced neuron injury in vitro through a PI3K/Akt-dependent mechanism.

Neurotoxicology 20100101

Treatment with alpha-lipoic acid reduces asymmetric dimethylarginine in patients with type 2 diabetes mellitus.

Translational research : the journal of laboratory and clinical medicine 20100101

Nitric oxide and thioredoxin type 1 modulate the activity of caspase 8 in HepG2 cells.

Biochemical and biophysical research communications 20100101

Assessing the reductive capacity of cells by measuring the recycling of ascorbic and lipoic acids.

Methods in molecular biology (Clifton, N.J.) 20100101

Antioxidant therapy in human endocrine disorders.

Medical science monitor : international medical journal of experimental and clinical research 20100101

Antioxidants and skin care: the essentials.

Plastic and reconstructive surgery 20100101

Design and synthesis of antioxidant alpha-lipoic acid hybrids.

Methods in molecular biology (Clifton, N.J.) 20100101

JS-K, a nitric oxide prodrug, has enhanced cytotoxicity in colon cancer cells with knockdown of thioredoxin reductase 1.

PloS one 20100101

Antioxidant therapies for traumatic brain injury.

Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics 20100101

Ascorbate inhibition of angiogenesis in aortic rings ex vivo and subcutaneous Matrigel plugs in vivo.

Journal of angiogenesis research 20100101

Cinnamomum cassia bark in two herbal formulas increases life span in Caenorhabditis elegans via insulin signaling and stress response pathways.

PloS one 20100101

Caloric restriction shortens lifespan through an increase in lipid peroxidation, inflammation and apoptosis in the G93A mouse, an animal model of ALS.

PloS one 20100101

Nutritional therapy to attenuate inflammation in HD patients: fact or fiction?

Nephrology news & issues 20100101

Mitochondrial fatty acid synthesis and respiration.

Biochimica et biophysica acta 20100101

[Multidrug resistance increase of tumor cells at the effect of radiation and phorbol ether depends on protein kinase C and reactive oxygen species].

Radiatsionnaia biologiia, radioecologiia 20100101

Protective effects of Spirulina maxima on hyperlipidemia and oxidative-stress induced by lead acetate in the liver and kidney.

Lipids in health and disease 20100101

A synthetic uric acid analog accelerates cutaneous wound healing in mice.

PloS one 20100101

Alpha-lipoic acid supplementation: a tool for obesity therapy?

Current pharmaceutical design 20100101

Role of carnitine in disease.

Nutrition & metabolism 20100101

Uncovering molecular biomarkers that correlate cognitive decline with the changes of hippocampus' gene expression profiles in Alzheimer's disease.

PloS one 20100101

Stereological analysis of sciatic nerve in chickens following neonatal pinealectomy: an experimental study.

Journal of brachial plexus and peripheral nerve injury 20100101

Combined R-alpha-lipoic acid and acetyl-L-carnitine exerts efficient preventative effects in a cellular model of Parkinson's disease.

Journal of cellular and molecular medicine 20100101

Optimal micronutrients delay mitochondrial decay and age-associated diseases.

Mechanisms of ageing and development 20100101

Signaling pathway networks mined from human pituitary adenoma proteomics data.

BMC medical genomics 20100101

[Alpha-lipoic acid triggers elimination of cells with abnormal nuclei in human carcinoma epidermoid cell line].

Tsitologiia 20100101

A forced titration study of the antioxidant and immunomodulatory effects of Ambrotose AO supplement.

BMC complementary and alternative medicine 20100101

Effects of duodenal redox status on calcium absorption and related genes expression in high-fat diet-fed mice.

Nutrition (Burbank, Los Angeles County, Calif.) 20100101

Improving the effect of incubation and oxidative stress on thawed spermatozoa from red deer by using different antioxidant treatments.

Reproduction, fertility, and development 20100101

Physiological and histopathological investigations on the effects of alpha-lipoic acid in rats exposed to malathion.

Journal of biomedicine & biotechnology 20100101

Metabolic pathways in the apicoplast of apicomplexa.

International review of cell and molecular biology 20100101

Comparative study of the antioxidant and reactive oxygen species scavenging properties in the extracts of the fruits of Terminalia chebula, Terminalia belerica and Emblica officinalis.

BMC complementary and alternative medicine 20100101

Nucleoside conjugates of quantum dots for characterization of G protein-coupled receptors: strategies for immobilizing A2A adenosine receptor agonists.

Journal of nanobiotechnology 20100101

Impact of dietary polyphenols on carbohydrate metabolism.

International journal of molecular sciences 20100101

Effect of beta-alanine supplementation on the onset of blood lactate accumulation (OBLA) during treadmill running: Pre/post 2 treatment experimental design.

Journal of the International Society of Sports Nutrition 20100101

Beneficial effects of a Q-ter based nutritional mixture on functional performance, mitochondrial function, and oxidative stress in rats.

PloS one 20100101

Establishment and metabolic analysis of a model microbial community for understanding trophic and electron accepting interactions of subsurface anaerobic environments.

BMC microbiology 20100101

Accumulation of advanced glycation end (AGEs) products in intensive care patients: an observational, prospective study.

BMC clinical pathology 20100101

Gabapentin enacarbil - clinical efficacy in restless legs syndrome.

Neuropsychiatric disease and treatment 20100101

Selective Vulnerabilities of N-methyl-D-aspartate (NMDA) Receptors During Brain Aging.

Frontiers in aging neuroscience 20100101

Cytoprotective effects of DL-alpha-lipoic acid or squalene on cyclophosphamide-induced oxidative injury: an experimental study on rat myocardium, testicles and urinary bladder.

Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20100101

Effects of epigallocatechin gallate, L-ascorbic acid, alpha-tocopherol, and dihydrolipoic acid on the formation of deoxyguanosine adducts derived from lipid peroxidation.

Nutrition and cancer 20100101

Complementary therapy in diabetic patients with chronic complications: a pilot study.

Bratislavske lekarske listy 20100101

The combined effects of sidestream smoke extracts and glycated serum albumin on endothelial cells and platelets.

Cardiovascular diabetology 20100101

Comparative proteome analysis of splenic lymphocytes in long-term high-fat diet and dietary supplement with lipoic acid mice.

Cellular immunology 20100101

Comparative study of the in vitro protective effects of several antioxidants on elongation factor 2 under oxidative stress conditions.

Bioscience, biotechnology, and biochemistry 20100101

Mitochondrial DNA mutations induce mitochondrial dysfunction, apoptosis and sarcopenia in skeletal muscle of mitochondrial DNA mutator mice.

PloS one 20100101

Quasi-drugs developed in Japan for the prevention or treatment of hyperpigmentary disorders.

International journal of molecular sciences 20100101

Ibuprofen and lipoic acid diamide as co-drug with neuroprotective activity: pharmacological properties and effects in beta-amyloid (1-40) infused Alzheimer's disease rat model.

International journal of immunopathology and pharmacology 20100101

[Atrial fibrillation in patients with type 2 diabetes mellitus: specific features of development and antirecurrence therapy].

Kardiologiia 20100101

Alpha-santalol, a chemopreventive agent against skin cancer, causes G2/M cell cycle arrest in both p53-mutated human epidermoid carcinoma A431 cells and p53 wild-type human melanoma UACC-62 cells.

BMC research notes 20100101

[Pharmacologic therapy in peripheral diabetic polyneuropathy].

Revista medico-chirurgicala a Societatii de Medici si Naturalisti din Iasi 20100101

Wnt1 neuroprotection translates into improved neurological function during oxidant stress and cerebral ischemia through AKT1 and mitochondrial apoptotic pathways.

Oxidative medicine and cellular longevity 20100101

Redox homeostasis of albumin in relation to alpha-lipoic acid and dihydrolipoic acid.

Oxidative medicine and cellular longevity 20100101

Integrative inference of gene-regulatory networks in Escherichia coli using information theoretic concepts and sequence analysis.

BMC systems biology 20100101

Laser ablation-based one-step generation and bio-functionalization of gold nanoparticles conjugated with aptamers.

Journal of nanobiotechnology 20100101

Bench-to-bedside review: Targeting antioxidants to mitochondria in sepsis.

Critical care (London, England) 20100101

Protective action of taurine, given as a pretreatment or as a posttreatment, against endotoxin-induced acute lung inflammation in hamsters.

Journal of biomedical science 20100101

Antiglycating potential of Zingiber officinalis and delay of diabetic cataract in rats.

Molecular vision 20100101

Antimalarial drug targets in Plasmodium falciparum predicted by stage-specific metabolic network analysis.

BMC systems biology 20100101

Possible role of alpha-lipoic acid in the treatment of peripheral nerve injuries.

Journal of brachial plexus and peripheral nerve injury 20100101

Chronic mercury poisoning: Report of two siblings.

Indian journal of occupational and environmental medicine 20100101

A systematic investigation of Escherichia coli central carbon metabolism in response to superoxide stress.

BMC systems biology 20100101

Global regulation of gene expression in response to cysteine availability in Clostridium perfringens.

BMC microbiology 20100101

The ubiquitous conserved glycopeptidase Gcp prevents accumulation of toxic glycated proteins.

mBio 20100101

Iron overload in diabetic retinopathy: a cause or a consequence of impaired mechanisms?

Experimental diabetes research 20100101

Protective role of taurine against arsenic-induced mitochondria-dependent hepatic apoptosis via the inhibition of PKCdelta-JNK pathway.

PloS one 20100101

Kinin B1 receptor enhances the oxidative stress in a rat model of insulin resistance: outcome in hypertension, allodynia and metabolic complications.

PloS one 20100101

Intracellular localization and interaction of mRNA binding proteins as detected by FRET.

BMC cell biology 20100101

Erythropoiesis and iron sulfur cluster biogenesis.

Advances in hematology 20100101

Brain mitochondrial dysfunction in aging, neurodegeneration, and Parkinson's disease.

Frontiers in aging neuroscience 20100101

Lipoic acid attenuates inflammation via cAMP and protein kinase A signaling.

PloS one 20100101

Prevention of mutation, cancer, and other age-associated diseases by optimizing micronutrient intake.

Journal of nucleic acids 20100101

Overexpression of biotin synthase and biotin ligase is required for efficient generation of sulfur-35 labeled biotin in E. coli.

BMC biotechnology 20100101

Deciphering the intracellular metabolism of Listeria monocytogenes by mutant screening and modelling.

BMC genomics 20100101

Preventive effects of Flos Perariae (Gehua) water extract and its active ingredient puerarin in rodent alcoholism models.

Chinese medicine 20100101

Gene discovery from Jatropha curcas by sequencing of ESTs from normalized and full-length enriched cDNA library from developing seeds.

BMC genomics 20100101

Controversy: is there a role for adjuvants in the management of male pattern hair loss?

Journal of cutaneous and aesthetic surgery 20100101

Effect of Ambrotose AO® on resting and exercise-induced antioxidant capacity and oxidative stress in healthy adults.

Nutrition journal 20100101

Protective Role of Tinospora cordifolia against Lead-induced Hepatotoxicity.

Toxicology international 20100101

Genome-wide influence of indel Substitutions on evolution of bacteria of the PVC superphylum, revealed using a novel computational method.

Genome biology and evolution 20100101

Behavioral impact of the regulation of the brain 2-oxoglutarate dehydrogenase complex by synthetic phosphonate analog of 2-oxoglutarate: implications into the role of the complex in neurodegenerative diseases.

International journal of Alzheimer's disease 20100101

Diabetic cardiomyopathy: from the pathophysiology of the cardiac myocytes to current diagnosis and management strategies.

Vascular health and risk management 20100101

Vitamin C, resveratrol and lipoic acid actions on isolated rat liver mitochondria: all antioxidants but different.

Redox report : communications in free radical research 20100101

Formulation of a medical food cocktail for Alzheimer's disease: beneficial effects on cognition and neuropathology in a mouse model of the disease.

PloS one 20100101

Prevention of diabetic eye disease: the commonest cause of blindness in individuals younger than 65 years.

Clinical ophthalmology (Auckland, N.Z.) 20100101

Validation of structural and functional lesions of diabetic retinopathy in mice.

Molecular vision 20100101

Genetic and chemical evaluation of Trypanosoma brucei oleate desaturase as a candidate drug target.

PloS one 20100101

Inactivation of the Ecs ABC transporter of Staphylococcus aureus attenuates virulence by altering composition and function of bacterial wall.

PloS one 20100101

Biliary epithelial apoptosis, autophagy, and senescence in primary biliary cirrhosis.

Hepatitis research and treatment 20100101

Acetaminophen-induced Hepato- and Nephrotoxicity and Amelioration by Silymarin and Terminalia chebula in Rats.

Toxicology international 20100101

Aldose reductase inhibition prevents metaplasia of airway epithelial cells.

PloS one 20100101

Treatment of cachexia in oncology.

Indian journal of palliative care 20100101

Bcl-2 expression alters the mitochondrial tri carboxyl Acid pathway in hepatic ischemic and reperfusion induced necrosis and apoptosis in rat liver.

Indian journal of pharmaceutical sciences 20100101

Stimulation of suicidal erythrocyte death by α-lipoic acid.

Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 20100101

Organic nitrates and nitrate resistance in diabetes: the role of vascular dysfunction and oxidative stress with emphasis on antioxidant properties of pentaerithrityl tetranitrate.

Experimental diabetes research 20100101

Insights into the development and treatment of cardiovascular disease: a role for animal models.

The open cardiovascular medicine journal 20100101

Glycoxidative stress and cardiovascular complications in experimentally-induced diabetes: effects of antioxidant treatment.

The open cardiovascular medicine journal 20100101

Resveratrol and red wine function as antioxidants in the nervous system without cellular proliferative effects during experimental diabetes.

Oxidative medicine and cellular longevity 20100101

Retinal redox stress and remodeling in cardiometabolic syndrome and diabetes.

Oxidative medicine and cellular longevity 20100101

Signaling of reactive oxygen and nitrogen species in Diabetes mellitus.

Oxidative medicine and cellular longevity 20100101

[Expression and catalytic properties NADP-isocitrate dehydrogenase from the rat liver under normal conditions and following administration of tumor necrosis factor-alpha or thioctic acid].

Biomeditsinskaia khimiia 20100101

Efficacy of alpha lipoic acid in adjunct with intralesional steroids and hyaluronidase in the management of oral submucous fibrosis.

Journal of cancer research and therapeutics 20100101

Effect of Holostemma annularis on the progression of diabetes induced by a high fructose diet in rats and in diabetic C57BL/6J ob/ob mice.

Diabetes, metabolic syndrome and obesity : targets and therapy 20100101

May diet and dietary supplements improve the wellness of multiple sclerosis patients? A molecular approach.

Autoimmune diseases 20100101

[Long-term effect of 3-week intravenous alpha-lipoic acid administration in symptomatic diabetic polyneutropathy with clinical manifestations].

Terapevticheskii arkhiv 20100101

Endogenous antioxidants and radical scavengers.

Advances in experimental medicine and biology 20100101

Inhibitory effect of rutin and curcumin on experimentally-induced calcium oxalate urolithiasis in rats.

Pharmacognosy research 20100101

Trends in aging and skin care: Ayurvedic concepts.

Journal of Ayurveda and integrative medicine 20100101

Role of Mitochondrial Enzymes and Sarcoplasmic ATPase in Cardioprotection Mediated by Aqueous Extract of Desmodium gangeticum (L) DC Root on Ischemic Reperfusion Injury.

Indian journal of pharmaceutical sciences 20100101

Tryptophan, Neurodegeneration and HIV-Associated Neurocognitive Disorder.

International journal of tryptophan research : IJTR 20100101

Novel mechanisms of central nervous system damage in HIV infection.

HIV/AIDS (Auckland, N.Z.) 20100101

Detection of cartilage oligomeric matrix protein using a quartz crystal microbalance.

Sensors (Basel, Switzerland) 20100101

Role of methylglyoxal in essential hypertension.

The International journal of angiology : official publication of the International College of Angiology, Inc 20100101

Aryl diazonium for biomolecules immobilization onto SPRi chips.

Chemphyschem : a European journal of chemical physics and physical chemistry 20091221

Nonparametric non-inferiority analyses in the three-arm design with active control and placebo.

Statistics in medicine 20091220

Modulatory role of lipoic acid on lipopolysaccharide-induced oxidative stress in adult rat Sertoli cells in vitro.

Chemico-biological interactions 20091210

Toward a rational design of multitarget-directed antioxidants: merging memoquin and lipoic acid molecular frameworks.

Journal of medicinal chemistry 20091210

Nanoscale in situ morphological study of proteins immobilized on gold thin films.

The journal of physical chemistry. B 20091203

alpha-Lipoic acid supplementation enhances heat shock protein production and decreases post exercise lactic acid concentrations in exercised standardbred trotters.

Research in veterinary science 20091201

Exercise therapy in type 2 diabetes.

Acta diabetologica 20091201

A current update on the use of alpha lipoic acid in the management of type 2 diabetes mellitus.

Endocrine, metabolic & immune disorders drug targets 20091201

Short-term supplementation with acetyl-L-carnitine and lipoic acid alters plasma protein carbonyl levels but does not improve cognition in aged beagles.

Experimental gerontology 20091201

Effect of alpha lipoic acid in a porcine in-stent restenosis model.

Journal of cardiology 20091201

A high-throughput model for fat graft assessment.

Lasers in surgery and medicine 20091201

Revisiting the ALA/N (alpha-lipoic acid/low-dose naltrexone) protocol for people with metastatic and nonmetastatic pancreatic cancer: a report of 3 new cases.

Integrative cancer therapies 20091201

[Comparison of the antioxidants lipoic acid pharmacokinetics in inner ear between intravenous and intratympanic administration in guinea pigs.].

Zhonghua er bi yan hou tou jing wai ke za zhi = Chinese journal of otorhinolaryngology head and neck surgery 20091201

Yeast display evolution of a kinetically efficient 13-amino acid substrate for lipoic acid ligase.

Journal of the American Chemical Society 20091118

Attenuation of myocardial apoptosis by alpha-lipoic acid through suppression of mitochondrial oxidative stress to reduce diabetic cardiomyopathy.

Chinese medical journal 20091105

Nitric oxide and dihydrolipoic acid modulate the activity of caspase 3 in HepG2 cells.

FEBS letters 20091103

17beta-hydroxysteroid dehydrogenase type 8 and carbonyl reductase type 4 assemble as a ketoacyl reductase of human mitochondrial FAS.

FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20091101

The effect of oral antioxidants on brachial artery flow-mediated dilation following 5 and 10 min of ischemia.

European journal of applied physiology 20091101

Effects of age, dietary, and behavioral enrichment on brain mitochondria in a canine model of human aging.

Experimental neurology 20091101

Cytoprotection against Cr(6+)-induced DNA damage by alpha-lipoic acid: implications in reducing occupational cancer risk.

Mutagenesis 20091101

Antioxidants and aging: NMR-based evidence of improved skeletal muscle perfusion and energetics.

American journal of physiology. Heart and circulatory physiology 20091101

Improved efficacy of appetite suppression by lipoic acid particles prepared by nanocomminution.

Drug development and industrial pharmacy 20091101

Painful diabetic neuropathy: advantage of novel drugs over old drugs?

Diabetes care 20091101

Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica.

PLoS genetics 20091101

Antioxidant properties of an endogenous thiol: Alpha-lipoic acid, useful in the prevention of cardiovascular diseases.

Journal of cardiovascular pharmacology 20091101

1,2-Bis(2-nitro-phen-yl)disulfane.

Acta crystallographica. Section E, Structure reports online 20091101

Effects of sulphur-containing compounds on plasma redox status in muscle-damaging exercise.

The Chinese journal of physiology 20091031

Liquid chromatographic determination of polythiols based on pre-column excimer fluorescence derivatization and its application to alpha-lipoic acid analysis.

Journal of chromatography. A 20091030

Lipoic acid effects on lipid peroxidation level, superoxide dismutase activity and monoamines concentration in rat hippocampus.

Neuroscience letters 20091023

Alpha-lipoic acid induces elevated S-adenosylhomocysteine and depletes S-adenosylmethionine.

Free radical biology & medicine 20091015

Synthesis and antioxidant properties of new chromone derivatives.

Bioorganic & medicinal chemistry 20091015

A 52-year-old woman with disabling peripheral neuropathy: review of diabetic polyneuropathy.

JAMA 20091007

Bridging of gold nanoparticles by functional polyphenylene dendrimers.

Langmuir : the ACS journal of surfaces and colloids 20091006

Time course of changes in the expression of insulin sensitivity-related genes after an acute load of virgin olive oil.

Omics : a journal of integrative biology 20091001

Alpha-lipoic acid attenuates cisplatin-induced acute kidney injury in mice by suppressing renal inflammation.

Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20091001

Evaluation of potential therapies for a mouse model of human age-related macular degeneration caused by delayed all-trans-retinal clearance.

Investigative ophthalmology & visual science 20091001

Behavioral response of dissimilatory perchlorate-reducing bacteria to different electron acceptors.

Applied microbiology and biotechnology 20091001

Choline supplementation reduces oxidative stress in mouse model of allergic airway disease.

European journal of clinical investigation 20091001

Dyslipidemia-induced neuropathy in mice: the role of oxLDL/LOX-1.

Diabetes 20091001

Alpha-lipoic acid as a dietary supplement: molecular mechanisms and therapeutic potential.

Biochimica et biophysica acta 20091001

The essential mycobacterial genes, fabG1 and fabG4, encode 3-oxoacyl-thioester reductases that are functional in yeast mitochondrial fatty acid synthase type 2.

Molecular genetics and genomics : MGG 20091001

Therapy and outcome of suspected alpha lipoic acid toxicity in two dogs.

Journal of veterinary emergency and critical care (San Antonio, Tex. : 2001) 20091001

[Expressions of NOS isoforms in the cavernous tissues of diabetic rat models].

Zhonghua nan ke xue = National journal of andrology 20091001

A love affair with vitamins.

The Journal of biological chemistry 20090925

Sequential injection system for phospholipase A2 activity evaluation: studies on liposomes using an environment-sensitive fluorescent probe.

Talanta 20090915

alpha-Lipoic acid prevents cisplatin-induced acute kidney injury in rats.

Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20090901

Gold nanoparticles stabilized by thermosensitive diblock copolymers of poly(ethylene glycol) and polyphosphoester.

Langmuir : the ACS journal of surfaces and colloids 20090901

Oxidative stress and dysregulation of the taurine transporter in high-glucose-exposed human Schwann cells: implications for pathogenesis of diabetic neuropathy.

American journal of physiology. Endocrinology and metabolism 20090901

Primary biliary cirrhosis.

Seminars in immunopathology 20090901

Design and synthesis of novel neuroprotective 1,2-dithiolane/chroman hybrids.

Bioorganic & medicinal chemistry 20090901

Antioxidant and radical scavenging activity of human colostrum, transitional and mature milk.

Journal of clinical biochemistry and nutrition 20090901

Marine-derived metabolites of S-adenosylmethionine as templates for new anti-infectives.

Marine drugs 20090901

Sage tea drinking improves lipid profile and antioxidant defences in humans.

International journal of molecular sciences 20090901

Cardioprotective effects of alpha-lipoic Acid on myocardial reperfusion injury: suppression of reactive oxygen species generation and activation of mitogen-activated protein kinase.

Korean circulation journal 20090901

Lipoic acid synthesis and attachment in yeast mitochondria.

The Journal of biological chemistry 20090828

The effect of acetyl-L-carnitine and R-alpha-lipoic acid treatment in ApoE4 mouse as a model of human Alzheimer's disease.

Journal of the neurological sciences 20090815

The Thermoplasma acidophilum LplA-LplB complex defines a new class of bipartite lipoate-protein ligases.

The Journal of biological chemistry 20090807

Radioprotective effect of DL-alpha-lipoic acid on mice skin fibroblasts.

Cell biology and toxicology 20090801

Age-associated impairment of Akt phosphorylation in primary rat hepatocytes is remediated by alpha-lipoic acid through PI3 kinase, PTEN, and PP2A.

Biogerontology 20090801

Palladium alpha-lipoic acid complex formulation enhances activities of Krebs cycle dehydrogenases and respiratory complexes I-IV in the heart of aged rats.

Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20090801

alpha-Lipoic acid modulates thiol antioxidant defenses and attenuates exercise-induced oxidative stress in standardbred trotters.

Free radical research 20090801

Gene expression profiling of aging in multiple mouse strains: identification of aging biomarkers and impact of dietary antioxidants.

Aging cell 20090801

A novel circuit overrides Adr1p control during expression of Saccharomyces cerevisiae 2-trans-enoyl-ACP reductase Etr1p of mitochondrial type 2 fatty acid synthase.

FEMS microbiology letters 20090801

A unique lipoylation system in the Archaea. Lipoylation in Thermoplasma acidophilum requires two proteins.

The FEBS journal 20090801

Protective effects of dietary antioxidants on proton total-body irradiation-mediated hematopoietic cell and animal survival.

Radiation research 20090801

Electron transfer mediators and other metabolites and cofactors in the treatment of mitochondrial dysfunction.

Nutrition reviews 20090801

Burning mouth syndrome: Identification, diagnosis, and treatment.

Journal of the American Academy of Nurse Practitioners 20090801

Mechanism of alpha-lipoic acid-induced apoptosis of lung cancer cells.

Annals of the New York Academy of Sciences 20090801

Direct electron transfer to a metalloenzyme redox center coordinated to a monolayer-protected cluster.

Journal of the American Chemical Society 20090729

Molecular mechanisms of lipoic acid modulation of T-type calcium channels in pain pathway.

The Journal of neuroscience : the official journal of the Society for Neuroscience 20090729

No selenium required: reactions catalyzed by mammalian thioredoxin reductase that are independent of a selenocysteine residue.

Biochemistry 20090707

Small-molecule targeting of the mitochondrial compartment with an endogenously cleaved reversible tag.

Chembiochem : a European journal of chemical biology 20090706

Synthesis and evaluation of the antioxidant and anti-inflammatory activity of novel coumarin-3-aminoamides and their alpha-lipoic acid adducts.

European journal of medicinal chemistry 20090701

High-sensitivity analysis of naturally occurring sugar chains, using a novel fluorescent linker molecule.

Journal of biochemistry 20090701

Monitoring white blood cell mitochondrial aldehyde dehydrogenase activity: implications for nitrate therapy in humans.

The Journal of pharmacology and experimental therapeutics 20090701

Alpha-lipoic acid and frataxin: a new indication for an old antioxidant?

Experimental neurology 20090701

Effect of alpha lipoic acid on the tardive dyskinesia and oxidative stress induced by haloperidol in rats.

Journal of neural transmission (Vienna, Austria : 1996) 20090701

The protective effect of alpha lipoic acid against traumatic brain injury in rats.

Free radical research 20090701

The ferredoxin-NADP+ reductase/ferredoxin electron transfer system of Plasmodium falciparum.

The FEBS journal 20090701

Environmental toxicants inhibit neuronal Jak tyrosine kinase by mitochondrial disruption.

Neurotoxicology 20090701

[The comparison of alpha-lipoic acid, melatonin, vitamin C and trolox effectiveness in decreasing DNA stand brakes and increasing plasma antioxidant power].

Polski merkuriusz lekarski : organ Polskiego Towarzystwa Lekarskiego 20090701

Oral co-administration of α-lipoic acid, quercetin and captopril prevents gallium arsenide toxicity in rats.

Environmental toxicology and pharmacology 20090701

Stimuli-responsive SERS nanoparticles: conformational control of plasmonic coupling and surface Raman enhancement.

Journal of the American Chemical Society 20090610

Hepatoprotective Activity of Licorice Water Extract against Cadmium-induced Toxicity in Rats.

Evidence-based complementary and alternative medicine : eCAM 20090601

The effect of lipoic acid on macro and trace metal levels in living tissues exposed to oxidative stress.

Anti-cancer agents in medicinal chemistry 20090601

Assessment of the antioxidant effectiveness of alpha-lipoic acid in healthy men exposed to muscle-damaging exercise.

Journal of physiology and pharmacology : an official journal of the Polish Physiological Society 20090601

A gold nanoparticle labeling strategy for the sensitive kinetic assay of the carbamate-acetylcholinesterase interaction by surface plasmon resonance.

Talanta 20090515

(R)-lipo-diaza-18-crown-6 self-assembled monolayer as a selective serotonin receptor.

Analytical chemistry 20090515

The evaluation of effects of lipoic acid on the lipid peroxidation, nitrite formation and antioxidant enzymes in the hippocampus of rats after pilocarpine-induced seizures.

Neuroscience letters 20090515

Stimuli-responsive antioxidant nanoprodrugs of NSAIDs.

International journal of pharmaceutics 20090508

Organocatalysts immobilised onto gold nanoparticles: application in the asymmetric reduction of imines with trichlorosilane.

Organic & biomolecular chemistry 20090507

Lack of efficacy of alpha-lipoic acid in burning mouth syndrome: a double-blind, randomized, placebo-controlled study.

European journal of pain (London, England) 20090501

Mechanisms of podocyte injury in diabetes: role of cytochrome P450 and NADPH oxidases.

Diabetes 20090501

Kinetic resolution of alpha-lipoic acid via enzymatic differentiation of a remote stereocenter.

Journal of industrial microbiology & biotechnology 20090501

Lipoic acid improves hypertriglyceridemia by stimulating triacylglycerol clearance and downregulating liver triacylglycerol secretion.

Archives of biochemistry and biophysics 20090501

Chaperone-aided expression of LipA and LplA followed by the increase in alpha-lipoic acid production.

Applied microbiology and biotechnology 20090501

Oral antioxidant supplementation does not prevent acute mountain sickness: double blind, randomized placebo-controlled trial.

QJM : monthly journal of the Association of Physicians 20090501

Effects of alpha-lipoic acid on transforming growth factor beta1-p38 mitogen-activated protein kinase-fibronectin pathway in diabetic nephropathy.

Metabolism: clinical and experimental 20090501

Inhibition of the alpha-ketoglutarate dehydrogenase-mediated reactive oxygen species generation by lipoic acid.

Journal of neurochemistry 20090501

Amperometric sensor for hydrogen peroxide based on immobilized cytochrome c on binary self-assembled monolayers.

Analytical sciences : the international journal of the Japan Society for Analytical Chemistry 20090501

The Degradation and Regeneration of alpha-Lipoic Acid under the Irradiation of UV Light in the Existence of Homocysteine.

Journal of clinical biochemistry and nutrition 20090501

In vivo transcriptional profiling of Listeria monocytogenes and mutagenesis identify new virulence factors involved in infection.

PLoS pathogens 20090501

Down-regulation of mitochondrial acyl carrier protein in mammalian cells compromises protein lipoylation and respiratory complex I and results in cell death.

The Journal of biological chemistry 20090424

Capacitive biosensor for quantification of trace amounts of DNA.

Biosensors & bioelectronics 20090415

An in vitro screening cascade to identify neuroprotective antioxidants in ALS.

Free radical biology & medicine 20090415

Metabolic interactions of AGE inhibitor pyridoxamine and antioxidant alpha-lipoic acid following 22 weeks of treatment in obese Zucker rats.

Life sciences 20090410

Mitochondrial fatty acid synthesis type II: more than just fatty acids.

The Journal of biological chemistry 20090403

Mitochondrial nutrients improve immune dysfunction in the type 2 diabetic Goto-Kakizaki rats.

Journal of cellular and molecular medicine 20090401

Mitochondrial decay in the brains of old rats: ameliorating effect of alpha-lipoic acid and acetyl-L-carnitine.

Neurochemical research 20090401

Plasmodium falciparum: organelle-specific acquisition of lipoic acid.

The international journal of biochemistry & cell biology 20090401

Protective effect of sulfhydryl-containing antioxidants against ischemia/reperfusion injury of prepubertal rat intestine.

Journal of gastroenterology and hepatology 20090401

A critical appraisal of erectile function in animal models of diabetes mellitus.

International journal of andrology 20090401

Chronic lipoic acid treatment worsens energy imbalances in streptozotocin-induced diabetic rats.

Diabetes & metabolism 20090401

Alpha-lipoic acid inhibits tumor necrosis factor-induced remodeling and weakening of human fetal membranes.

Biology of reproduction 20090401

Influence of anchoring ligands and particle size on the colloidal stability and in vivo biodistribution of polyethylene glycol-coated gold nanoparticles in tumor-xenografted mice.

Biomaterials 20090401

Lipoic acid increases heat shock protein expression and inhibits stress kinase activation to improve insulin signaling in skeletal muscle from high-fat-fed rats.

Journal of applied physiology (Bethesda, Md. : 1985) 20090401

Alpha-lipoic acid modifies oxidative stress parameters in sickle cell trait subjects and sickle cell patients.

Clinical nutrition (Edinburgh, Scotland) 20090401

Probing and preventing quantum dot-induced cytotoxicity with multimodal alpha-lipoic acid in multiple dimensions of the peripheral nervous system.

Nanomedicine (London, England) 20090401

Prophylaxis with alpha-lipoic acid against lipopolysaccharide-induced brain injury in rats.

Archivum immunologiae et therapiae experimentalis 20090401

[Effects of sustained-release alpha-lipoic acid tablet on blood lipid, blood sugar and insulin in hyperlipidemic New Zealand rabbits].

Nan fang yi ke da xue xue bao = Journal of Southern Medical University 20090401

Protective effect of lipoic acid against acrolein-induced cytotoxicity in IMR-90 human fibroblasts.

Journal of nutritional science and vitaminology 20090401

Lipoic acid-palladium complex interaction with DNA, voltammetric and AFM characterization.

Talanta 20090315

Preparation and characterization of antioxidant nanospheres from multiple alpha-lipoic acid-containing compounds.

Bioorganic & medicinal chemistry letters 20090315

Simple, clickable protocol for atomic force microscopy tip modification and its application for trace ricin detection by recognition imaging.

Langmuir : the ACS journal of surfaces and colloids 20090303

Oral antioxidants and cardiovascular health in the exercise-trained and untrained elderly: a radically different outcome.

Clinical science (London, England : 1979) 20090301

Heat treatment improves glucose tolerance and prevents skeletal muscle insulin resistance in rats fed a high-fat diet.

Diabetes 20090301

Lipoic acid synthase (LASY): a novel role in inflammation, mitochondrial function, and insulin resistance.

Diabetes 20090301

Alpha-lipoic acid potently inhibits peroxynitrite-mediated DNA strand breakage and hydroxyl radical formation: implications for the neuroprotective effects of alpha-lipoic acid.

Molecular and cellular biochemistry 20090301

Induction of autoimmune cholangitis in non-obese diabetic (NOD).1101 mice following a chemical xenobiotic immunization.

Clinical and experimental immunology 20090301

Alpha lipoic acid in burning mouth syndrome--a randomized double-blind placebo-controlled trial.

Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology 20090301

Alpha-lipoic acid reduces congenital malformations in the offspring of diabetic mice.

Diabetes/metabolism research and reviews 20090301

Physicochemical characteristics, cytotoxicity, and antioxidant activity of three lipid nanoparticulate formulations of alpha-lipoic acid.

AAPS PharmSciTech 20090301

The effects of palm oil tocotrienol-rich fraction supplementation on biochemical parameters, oxidative stress and the vascular wall of streptozotocin-induced diabetic rats.

Clinics (Sao Paulo, Brazil) 20090301

Effect of alpha-lipoic acid on LPS-induced oxidative stress in the heart.

Journal of physiology and pharmacology : an official journal of the Polish Physiological Society 20090301

[Burning mouth syndrome and alpha-lipoic acid].

Actas dermo-sifiliograficas 20090301

[Progress in the research on multi-target-directed drugs against Alzheimer's disease].

Yao xue xue bao = Acta pharmaceutica Sinica 20090301

Lipoic acid prevents body weight gain induced by a high fat diet in rats: effects on intestinal sugar transport.

Journal of physiology and biochemistry 20090301

Oxidative stress and neurodegenerative diseases: a review of upstream and downstream antioxidant therapeutic options.

Current neuropharmacology 20090301

Stabilizing effects of eicosapentaenoic acid on Kv1.5 channel protein expressed in mammalian cells.

European journal of pharmacology 20090214

Carotenoid extraction from plants using a novel, environmentally friendly solvent.

Journal of agricultural and food chemistry 20090211

Design of a versatile chemical assembly method for patterning colloidal nanoparticles.

Nanotechnology 20090211

CYP450 2B4 covalently attached to carbon and gold screen printed electrodes by diazonium salt and thiols monolayers.

Analytica chimica acta 20090202

Neuronal mitochondrial amelioration by feeding acetyl-L-carnitine and lipoic acid to aged rats.

Journal of cellular and molecular medicine 20090201

The chemical pathway to primary biliary cirrhosis.

Clinical reviews in allergy & immunology 20090201

Enhanced expression of Janus kinase-signal transducer and activator of transcription pathway members in human diabetic nephropathy.

Diabetes 20090201

Functional characterisation of Fab'-fragments self-assembled onto hydrophilic gold surfaces.

Colloids and surfaces. B, Biointerfaces 20090201

HMOX1 and NQO1 genes are upregulated in response to contact sensitizers in dendritic cells and THP-1 cell line: role of the Keap1/Nrf2 pathway.

Toxicological sciences : an official journal of the Society of Toxicology 20090201

Alpha-lipoic acid improves acetic acid-induced gastric ulcer healing in rats.

Inflammation 20090201

Ethacrynic and alpha-lipoic acids inhibit vaccinia virus late gene expression.

Antiviral research 20090201

Chronic antioxidant therapy reduces oxidative stress in a mouse model of Alzheimer's disease.

Free radical research 20090201

Vitreal pharmacokinetics of biotinylated ganciclovir: role of sodium-dependent multivitamin transporter expressed on retina.

Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics 20090201

Effects of antioxidant supplements intervention on the level of plasma inflammatory molecules and disease severity of rheumatoid arthritis patients.

Journal of the American College of Nutrition 20090201

Fabrication of an alpha-lipoic acid-eluting poly-(D,L-lactide-co-caprolactone) cuff for the inhibition of neointimal formation.

Experimental & molecular medicine 20090131

Distribution study of orally administered lipoic acid in rat brain tissues.

Brain research 20090128

The evaluation of effect of alpha-lipoic acid and vitamin E on the lipid peroxidation, gamma-amino butyric acid and serotonin level in the brain of mice (Mus musculus) acutely intoxicated with lindane.

Journal of the neurological sciences 20090115

Switching from pathogenetic treatment with alpha-lipoic acid to gabapentin and other analgesics in painful diabetic neuropathy: a real-world study in outpatients.

Journal of diabetes and its complications 20090101

Radical scavengers for elderly patients with age-related hearing loss.

Acta oto-laryngologica 20090101

Effect of alpha-lipoic acid on visual evoked potentials in rats exposed to sulfite.

Neurotoxicology and teratology 20090101

Oxidative stress mediates protein kinase C activation and advanced glycation end product formation in a mesangial cell model of diabetes and high protein diet.

American journal of nephrology 20090101

The 'rejuvenatory' impact of lipoic acid on mitochondrial function in aging rats may reflect induction and activation of PPAR-gamma coactivator-1alpha.

Medical hypotheses 20090101

Role of NADPH-cytochrome P450 reductase and cytochrome-b5/NADH-b5 reductase in variability of CYP3A activity in human liver microsomes.

Drug metabolism and disposition: the biological fate of chemicals 20090101

Antioxidant properties of alpha-lipoic acid: effects on red blood membrane permeability and adaptation of isolated rat heart to reversible ischemia.

Molecular and cellular biochemistry 20090101

Mice with heterozygous deficiency of lipoic acid synthase have an increased sensitivity to lipopolysaccharide-induced tissue injury.

Journal of leukocyte biology 20090101

Efficacy of alpha lipoic acid in burning mouth syndrome: a randomized, placebo-treatment study.

Journal of oral rehabilitation 20090101

Drug-induced insulin autoimmune syndrome.

Diabetes research and clinical practice 20090101

The comparison of antioxidant and hematological properties of N-acetylcysteine and alpha-lipoic acid in physically active males.

Physiological research 20090101

Dihydro-alpha-lipoic acid has more potent cytotoxicity than alpha-lipoic acid.

In vitro cellular & developmental biology. Animal 20090101

Iron behaving badly: inappropriate iron chelation as a major contributor to the aetiology of vascular and other progressive inflammatory and degenerative diseases.

BMC medical genomics 20090101

Combining chemical genomics screens in yeast to reveal spectrum of effects of chemical inhibition of sphingolipid biosynthesis.

BMC microbiology 20090101

Complete genome sequence of the aerobic CO-oxidizing thermophile Thermomicrobium roseum.

PloS one 20090101

In Vitro Effects of the Reduced Form of Coenzyme Q(10) on Secretion Levels of TNF-alpha and Chemokines in Response to LPS in the Human Monocytic Cell Line THP-1.

Journal of clinical biochemistry and nutrition 20090101

Dietary supplementation with a combination of alpha-lipoic acid, acetyl-L-carnitine, glycerophosphocoline, docosahexaenoic acid, and phosphatidylserine reduces oxidative damage to murine brain and improves cognitive performance.

Nutrition research (New York, N.Y.) 20090101

MTDL design strategy in the context of Alzheimer's disease: from lipocrine to memoquin and beyond.

Current pharmaceutical design 20090101

A comparative genomics study of genetic products potentially encoding ladderane lipid biosynthesis.

Biology direct 20090101

Effect of alpha lipoic acid on oxidative stress and vascular wall of diabetic rats.

Romanian journal of morphology and embryology = Revue roumaine de morphologie et embryologie 20090101

Polyethylene glycol-based bidentate ligands to enhance quantum dot and gold nanoparticle stability in biological media.

Nature protocols 20090101

Multifunctional ligands based on dihydrolipoic acid and polyethylene glycol to promote biocompatibility of quantum dots.

Nature protocols 20090101

Glucosamine/chondroitin/primorine combination therapy for osteoarthritis.

Drugs of today (Barcelona, Spain : 1998) 20090101

Enhanced antitumor efficacy of cisplatin in combination with HemoHIM in tumor-bearing mice.

BMC cancer 20090101

Cellular localization of kinin B1 receptor in the spinal cord of streptozotocin-diabetic rats with a fluorescent [Nalpha-Bodipy]-des-Arg9-bradykinin.

Journal of neuroinflammation 20090101

Effects of alpha-lipoic acid administration on plasma glucose levels, total malondialdehyde values and withdrawal signs in rats treated with morphine or morphine plus naloxone.

Arzneimittel-Forschung 20090101

Dose-related cytoprotective effect of alpha-lipoic acid on hydrogen peroxide-induced oxidative stress to pancreatic beta cells.

Free radical research 20090101

Prolonged treatment with N-acetylcystine delays liver recovery from acetaminophen hepatotoxicity.

Critical care (London, England) 20090101

N-acetylcysteine amide decreases oxidative stress but not cell death induced by doxorubicin in H9c2 cardiomyocytes.

BMC pharmacology 20090101

Knockout studies reveal an important role of Plasmodium lipoic acid protein ligase A1 for asexual blood stage parasite survival.

PloS one 20090101

Bench-to-bedside review: Angiopoietin signalling in critical illness - a future target?

Critical care (London, England) 20090101

Myocardial overexpression of Mecr, a gene of mitochondrial FAS II leads to cardiac dysfunction in mouse.

PloS one 20090101

Pharmacological Treatment of Alzheimer's Disease: Is it Progressing Adequately?

The open neurology journal 20090101

Treatment of carpal tunnel syndrome with alpha-lipoic acid.

European review for medical and pharmacological sciences 20090101

Bilobalide modulates serotonin-controlled behaviors in the nematode Caenorhabditis elegans.

BMC neuroscience 20090101

Alveolar hypoxia, alveolar macrophages, and systemic inflammation.

Respiratory research 20090101

[Effect of alpha-lipoic acid on the sensitivity of transformed fibroblasts to lysis by natural killer cells. Comparison with NAC action].

Tsitologiia 20090101

NAC: still the way to go.

Critical care (London, England) 20090101

Hypoglycemic and beta cell protective effects of andrographolide analogue for diabetes treatment.

Journal of translational medicine 20090101

Evaluation of lenticular antioxidant and redox system components in the lenses of acetyl-L-carnitine treatment in BSO-induced glutathione deprivation.

Molecular vision 20090101

Association between carotid diameter and the advanced glycation end product N-epsilon-carboxymethyllysine (CML).

Cardiovascular diabetology 20090101

Alpha-lipoic acid attenuates cisplatin-induced tubulointerstitial injuries through inhibition of mitochondrial bax translocation in rats.

Nephron. Experimental nephrology 20090101

Glycine and glycine receptor signalling in non-neuronal cells.

Frontiers in molecular neuroscience 20090101

Islet endothelial activation and oxidative stress gene expression is reduced by IL-1Ra treatment in the type 2 diabetic GK rat.

PloS one 20090101

Caenorhabditis elegans F09E10.3 encodes a putative 3-oxoacyl-thioester reductase of mitochondrial type 2 fatty acid synthase FASII that is functional in yeast.

Journal of biomedicine & biotechnology 20090101

Immobilization of a naphthalene diimide-DNA complex on the gold through dithiolane moieties.

Nucleic acids symposium series (2004) 20090101

Genome-wide deletion mutant analysis reveals genes required for respiratory growth, mitochondrial genome maintenance and mitochondrial protein synthesis in Saccharomyces cerevisiae.

Genome biology 20090101

Lipoic acid attenuates high fat diet-induced chronic oxidative stress and immunosuppression in mice jejunum: a microarray analysis.

Cellular immunology 20090101

Proteome analysis of the Escherichia coli heat shock response under steady-state conditions.

Proteome science 20090101

[Present-day possibilities of correcting impaired autoregulation of the cerebral circulation].

Angiologiia i sosudistaia khirurgiia = Angiology and vascular surgery 20090101

The amidase domain of lipoamidase specifically inactivates lipoylated proteins in vivo.

PloS one 20090101

Impact of therapy with alpha-lipoic acid (ALA) on the oxidative stress in the controlled NIDDM: a possible preventive way against the organ dysfunction?

Archives of gerontology and geriatrics 20090101

Protective effect of melatonin against mitomycin C-induced genotoxic damage in peripheral blood of rats.

Journal of biomedicine & biotechnology 20090101

Physiological function of mycobacterial mtFabD, an essential malonyl-CoA:AcpM transacylase of type 2 fatty acid synthase FASII, in yeast mct1Delta cells.

Comparative and functional genomics 20090101

The use of alpha-lipoic acid (ALA), gamma linolenic acid (GLA) and rehabilitation in the treatment of back pain: effect on health-related quality of life.

International journal of immunopathology and pharmacology 20090101

Multifunctional lipoic acid conjugates.

Current medicinal chemistry 20090101

Water-soluble fullerene (C60) inhibits the development of arthritis in the rat model of arthritis.

International journal of nanomedicine 20090101

Water-soluble fullerene (C60) inhibits the osteoclast differentiation and bone destruction in arthritis.

International journal of nanomedicine 20090101

Neuromuscular electrical stimulation and dietary interventions to reduce oxidative stress in a secondary progressive multiple sclerosis patient leads to marked gains in function: a case report.

Cases journal 20090101

A C. elegans model for mitochondrial fatty acid synthase II: the longevity-associated gene W09H1.5/mecr-1 encodes a 2-trans-enoyl-thioester reductase.

PloS one 20090101

Intraperitoneal Alpha-Lipoic Acid to prevent neural damage after crush injury to the rat sciatic nerve.

Journal of brachial plexus and peripheral nerve injury 20090101

Self-assembled tethered bimolecular lipid membranes.

Advances in clinical chemistry 20090101

Arachidonic acid-induced apoptosis in rat hepatoma AS-30D cells is mediated by reactive oxygen species.

Acta biochimica Polonica 20090101

[Structural and functional condition of the left ventricle in patients with type 2 diabetes mellitus complicated with diabetic autonomic neuropathy].

Likars'ka sprava 20090101

Clinical applications of alpha-lipoic acid in the management of neurological disorders besides carpal tunnel syndrome.

European review for medical and pharmacological sciences 20090101

Recent developments in multiple sclerosis therapeutics.

BMC medicine 20090101

Phylogenomics of the oxidative phosphorylation in fungi reveals extensive gene duplication followed by functional divergence.

BMC evolutionary biology 20090101

Modulation of cytochrome P450 enzyme system by selected flavonoids.

Neuro endocrinology letters 20090101

Alpha-lipoic Acid and diabetic neuropathy.

The review of diabetic studies : RDS 20090101

[Correction of disordered cerebral blood flow autoregulation in atherosclerosis].

Angiologiia i sosudistaia khirurgiia = Angiology and vascular surgery 20090101

Effects of alpha-lipoic acid on cell proliferation and apoptosis in MDA-MB-231 human breast cells.

Nutrition research and practice 20090101

Topical treatment of melasma.

Indian journal of dermatology 20090101

[Effect of alpha-lipoic acid on fibroblasts 3T3 and 3T3-SV40. Comparison with N-acetylcysteine action].

Tsitologiia 20090101

Identification of the Leishmania major proteins LmjF07.0430, LmjF07.0440, and LmjF27.2440 as components of fatty acid synthase II.

Journal of biomedicine & biotechnology 20090101

Comparison of oxidative stress among migraineurs, tension-type headache subjects, and a control group.

Annals of Indian Academy of Neurology 20090101

Resveratrol preserves cerebrovascular density and cognitive function in aging mice.

Frontiers in aging neuroscience 20090101

Acute seizure activity promotes lipid peroxidation, increased nitrite levels and adaptive pathways against oxidative stress in the frontal cortex and striatum.

Oxidative medicine and cellular longevity 20090101

Structural, chemical and biological aspects of antioxidants for strategies against metal and metalloid exposure.

Oxidative medicine and cellular longevity 20090101

Oxidative stress in the hippocampus during experimental seizures can be ameliorated with the antioxidant ascorbic acid.

Oxidative medicine and cellular longevity 20090101

Role of creatine supplementation on exercise-induced cardiovascular function and oxidative stress.

Oxidative medicine and cellular longevity 20090101

Bortezomib in the management of multiple myeloma.

Cancer management and research 20090101

Ferric reducing antioxidant power and square wave voltammetry for assay of low molecular weight antioxidants in blood plasma: performance and comparison of methods.

Sensors (Basel, Switzerland) 20090101

Direct electrochemistry of horseradish peroxidase-gold nanoparticles conjugate.

Sensors (Basel, Switzerland) 20090101

Snapshots of catalysis in the E1 subunit of the pyruvate dehydrogenase multienzyme complex.

Structure (London, England : 1993) 20081212

Short interfering RNA against transient receptor potential vanilloid 1 attenuates cisplatin-induced hearing loss in the rat.

The Journal of neuroscience : the official journal of the Society for Neuroscience 20081203

Alpha lipoic acid possess dual antioxidant and lipid lowering properties in atherosclerotic-induced New Zealand White rabbit.

Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 20081201

Dietary supplementation with N-acetylcysteine, alpha-tocopherol and alpha-lipoic acid prevents age related decline in Na(+),K (+)-ATPase activity and associated peroxidative damage in rat brain synaptosomes.

Biogerontology 20081201

Alpha-lipoic acid prevents mitochondrial damage and neurotoxicity in experimental chemotherapy neuropathy.

Experimental neurology 20081201

Dihydrolipoic acid inhibits tetrachlorohydroquinone-induced tumor promotion through prevention of oxidative damage.

Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20081201

A proteome analysis of the cadmium and mercury response in Corynebacterium glutamicum.

Proteomics 20081201

Xenobiotic incorporation into pyruvate dehydrogenase complex can occur via the exogenous lipoylation pathway.

Hepatology (Baltimore, Md.) 20081201

Management of painful diabetic neuropathy.

Expert opinion on pharmacotherapy 20081201

Stability of vitamin C derivatives in topical formulations containing lipoic acid, vitamins A and E.

International journal of cosmetic science 20081201

Blueberry-enriched diet ameliorates age-related declines in NMDA receptor-dependent LTP.

Age (Dordrecht, Netherlands) 20081201

Comparison of in vitro bioactivation of flutamide and its cyano analogue: evidence for reductive activation by human NADPH:cytochrome P450 reductase.

Chemical research in toxicology 20081201

Mutated glutathione-S-transferase reduced airway inflammation by limiting oxidative stress and Th2 response.

Free radical biology & medicine 20081115

Sulfhydryl systems are a critical factor in the zebrafish developmental toxicity of the dithiocarbamate sodium metam (NaM).

Aquatic toxicology (Amsterdam, Netherlands) 20081111

Investigation of the drug-drug interaction between alpha-lipoic acid and valproate via mitochondrial beta-oxidation.

Pharmaceutical research 20081101

The beneficial effect of coenzyme Q10 and lipoic acid on obstructive bladder dysfunction in the rabbit.

The Journal of urology 20081101

Alpha-lipoic acid attenuates hemorrhagic shock-induced apoptotic signaling and vascular hyperpermeability.

Shock (Augusta, Ga.) 20081101

Intestinal tumour chemoprevention with the antioxidant lipoic acid stimulates the growth of breast cancer.

European journal of cancer (Oxford, England : 1990) 20081101

Alpha-lipoic acid decreases hepatic lipogenesis through adenosine monophosphate-activated protein kinase (AMPK)-dependent and AMPK-independent pathways.

Hepatology (Baltimore, Md.) 20081101

Alpha-lipoic acid supplementation and diabetes.

Nutrition reviews 20081101

Pharmacokinetics of different formulations of tioctic (alpha-lipoic) acid in healthy volunteers.

Clinical and experimental hypertension (New York, N.Y. : 1993) 20081101

Nutritional supplementation for type 2 diabetes: a systematic review.

Ophthalmic & physiological optics : the journal of the British College of Ophthalmic Opticians (Optometrists) 20081101

The role of alpha-lipoic acid in diabetic polyneuropathy treatment.

Bosnian journal of basic medical sciences 20081101

Influence of alpha lipoic acid on antioxidant status in D-galactosamine-induced hepatic injury.

Toxicology and industrial health 20081101

[Two patients with mitochondrial respiratory chain disease].

Nederlands tijdschrift voor geneeskunde 20081018

Synthesis and surface self-assembly of [3]rotaxane-porphyrin conjugates: toward the development of a supramolecular surface tweezer for C60.

Langmuir : the ACS journal of surfaces and colloids 20081007

Optimization of octanoic acid and sulfur donor concentrations for lipoic acid production by Pseudomonas reptilivora.

Biotechnology letters 20081001

A computational investigation of sulfur-containing heterocyclic components from the anal sac secretions of Mustela species.

Journal of molecular modeling 20081001

Oral benfotiamine plus alpha-lipoic acid normalises complication-causing pathways in type 1 diabetes.

Diabetologia 20081001

Compounds that confer thermal stress resistance and extended lifespan.

Experimental gerontology 20081001

Interactions of the advanced glycation end product inhibitor pyridoxamine and the antioxidant alpha-lipoic acid on insulin resistance in the obese Zucker rat.

Metabolism: clinical and experimental 20081001

Control of cellular redox status and upregulation of quinone reductase NQO1 via Nrf2 activation by alpha-lipoic acid in human leukemia HL-60 cells.

International journal of oncology 20081001

[Thermodynamically controlled deracemization utilizing inclusion complexation].

Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 20081001

Is the anti-hypertensive effect of dietary supplements via aldehydes reduction evidence based? A systematic review.

Clinical and experimental hypertension (New York, N.Y. : 1993) 20081001

Drugs for the treatment of diabetes complications. Zycose: a new player in the field?

Drugs of today (Barcelona, Spain : 1998) 20081001

Recent advances in pharmacotherapy of glaucoma.

Indian journal of pharmacology 20081001

Neuropharmacology.

Indian journal of pharmacology 20081001

Toxicology.

Indian journal of pharmacology 20081001

Miscellaneous.

Indian journal of pharmacology 20081001

The role of lipoic acid in prevention of nitroglycerin tolerance.

European journal of pharmacology 20080904

Alpha-lipoic acid treatment of 31 patients with sore, burning mouth.

Oral diseases 20080901

Opposite effects of alpha-lipoic acid on antioxidation and long-term potentiation in control and chronically lead-exposed rats.

Naunyn-Schmiedeberg's archives of pharmacology 20080901

Small molecular antioxidants effectively protect from PUVA-induced oxidative stress responses underlying fibroblast senescence and photoaging.

Free radical biology & medicine 20080901

Pericyte migration: a novel mechanism of pericyte loss in experimental diabetic retinopathy.

Diabetes 20080901

Metabolically favorable remodeling of human adipose tissue by human adenovirus type 36.

Diabetes 20080901

Examining the evidence: complementary adjunctive therapies for multiple sclerosis.

Neurological research 20080901

Modulation of antioxidant and detoxification responses mediated by lipoic acid in the fish Corydoras paleatus (Callychthyidae).

Comparative biochemistry and physiology. Toxicology & pharmacology : CBP 20080901

Experimental determination of quantum dot size distributions, ligand packing densities, and bioconjugation using analytical ultracentrifugation.

Nano letters 20080901

Lipid lowering effect of antioxidant alpha-lipoic Acid in experimental atherosclerosis.

Journal of clinical biochemistry and nutrition 20080901

The oxidative stress and the mitochondrial dysfunction caused by endotoxemia are prevented by alpha-lipoic acid.

Free radical research 20080901

[Effects of cytochrome P450 isozymes on aristolochic acid renal cytotoxicity].

Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20080901

[Effect of lipoic acid on gene expression related to oxidative stress, lipid and glucose metabolism of mice fed with high fat diet].

Wei sheng yan jiu = Journal of hygiene research 20080901

Lipoic acid rescues DBA mice from early-onset age-related hearing impairment.

Neuroreport 20080827

TNFalpha-induced NF-kappaB activation and cell oxidant production are modulated by hexameric procyanidins in Caco-2 cells.

Archives of biochemistry and biophysics 20080815

Lipoic acid stimulates cAMP production via the EP2 and EP4 prostanoid receptors and inhibits IFN gamma synthesis and cellular cytotoxicity in NK cells.

Journal of neuroimmunology 20080813

Antioxidant effects of methionine, alpha-lipoic acid, N-acetylcysteine and homocysteine on lead-induced oxidative stress to erythrocytes in rats.

Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie 20080801

The ketogenic diet increases mitochondrial glutathione levels.

Journal of neurochemistry 20080801

Metabolomics approach for determining growth-specific metabolites based on Fourier transform ion cyclotron resonance mass spectrometry.

Analytical and bioanalytical chemistry 20080801

Loss of tolerance in C57BL/6 mice to the autoantigen E2 subunit of pyruvate dehydrogenase by a xenobiotic with ensuing biliary ductular disease.

Hepatology (Baltimore, Md.) 20080801

Effect of oil-in-water lipid emulsions prepared with fish oil or soybean oil on the growth of MCF-7 cells and HepG2 cells.

The Journal of pharmacy and pharmacology 20080801

Multi-analyte sensing: a chemometrics approach to understanding the merits of electrode arrays versus single electrodes.

The Analyst 20080801

In response to Tong TC, et al. Comparative treatment of alpha-amanitin poisoning with N-acetylcysteine, benzylpenicillin, cimetidine, thioctic acid, and silybin in a murine model.

Annals of emergency medicine 20080801

Plasma malondialdehyde levels and opiate withdrawal signs observed in rats treated with morphine plus naloxone: effects of alpha-lipoic acid administration.

Fundamental & clinical pharmacology 20080801

A study of the antioxidant effect of alpha lipoic acids on sperm quality.

Clinics (Sao Paulo, Brazil) 20080801

[Effects of huanglian jiedu decoction on the oxidative stress of liver mitochondria in insulin resistant Rats].

Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine 20080801

A 41-year-old man with polyarthritis and severe autonomic neuropathy.

Therapeutics and clinical risk management 20080801

Vitamin B for treating peripheral neuropathy.

The Cochrane database of systematic reviews 20080716

Dietary lipoic acid-dependent changes in the activity and mRNA levels of hepatic lipogenic enzymes in rats.

The British journal of nutrition 20080701

Protective effects of R-alpha-lipoic acid and acetyl-L-carnitine in MIN6 and isolated rat islet cells chronically exposed to oleic acid.

Journal of cellular biochemistry 20080701

Effect of co-enzyme Q10 and alpha-lipoic acid on response of rabbit urinary bladder to repetitive stimulation and in vitro ischemia.

Urology 20080701

Antioxidants and free radical scavengers do not consistently delay seizure onset in animal models of acute seizures.

Epilepsy & behavior : E&B 20080701

Role of AMP-activated protein kinase in the control of appetite.

Journal of neuroendocrinology 20080701

Targeting oxidative stress in surgery: effects of ageing and therapy.

Experimental gerontology 20080701

Label-free detection of antibody-antigen interactions on (R)-lipo-diaza-18-crown-6 self-assembled monolayer modified gold electrodes.

Analytical chemistry 20080701

Synthesis and anti-melanogenic effects of lipoic acid-polyethylene glycol ester.

The Journal of pharmacy and pharmacology 20080701

Charge dependence of ligand release and monolayer stability of gold nanoparticles by biogenic thiols.

Bioconjugate chemistry 20080701

Synthesis and anticancer properties of water-soluble zinc ionophores.

Cancer research 20080701

Early lipoic acid intake protects retina of diabetic mice.

Free radical research 20080701

Effect of a Diet Supplemented with alpha-Tocopherol and beta-Carotene on ATP and Antioxidant Levels after Hepatic Ischemia-Reperfusion.

Journal of clinical biochemistry and nutrition 20080701

Glycine cleavage system: reaction mechanism, physiological significance, and hyperglycinemia.

Proceedings of the Japan Academy. Series B, Physical and biological sciences 20080701

Toward reliable gold nanoparticle patterning on self-assembled DNA nanoscaffold.

Journal of the American Chemical Society 20080625

Selective and sensitive determination of lipoyllysine (protein-bound alpha-lipoic acid) in biological specimens by high-performance liquid chromatography with fluorescence detection.

Analytica chimica acta 20080623

PDK-1 regulates lactate production in hypoxia and is associated with poor prognosis in head and neck squamous cancer.

British journal of cancer 20080617

Chitosan microspheres for encapsulation of alpha-lipoic acid.

International journal of pharmaceutics 20080605

The effect of oral alpha-lipoic acid on oxidative stress in adolescents with type 1 diabetes mellitus.

Pediatric diabetes 20080601

Binding of lipoic acid induces conformational change and appearance of a new binding site in methylglyoxal modified serum albumin.

The protein journal 20080601

Lipoic acid prevents high-fat diet-induced dyslipidemia and oxidative stress: a microarray analysis.

Nutrition (Burbank, Los Angeles County, Calif.) 20080601

Peroxiredoxin 6 in human brain: molecular forms, cellular distribution and association with Alzheimer's disease pathology.

Acta neuropathologica 20080601

Efficacy of DL-alpha lipoic acid against systemic inflammation-induced mice: antioxidant defense system.

Molecular and cellular biochemistry 20080601

Is alpha-lipoic acid a scavenger of reactive oxygen species in vivo? Evidence for its initiation of stress signaling pathways that promote endogenous antioxidant capacity.

IUBMB life 20080601

Synthesis of new antioxidant conjugates and their in vitro hydrolysis with Stratum corneum enzymes.

International journal of cosmetic science 20080601

Dietary lipoic acid supplementation can mimic or block the effect of dietary restriction on life span.

Mechanisms of ageing and development 20080601

Acetyl-L-carnitine and alpha-lipoic acid: possible neurotherapeutic agents for mood disorders?

Expert opinion on investigational drugs 20080601

Ability of alpha-lipoic acid to reverse the diabetic cystopathy in a rat model.

Acta pharmacologica Sinica 20080601

Lipoic acid: a novel therapeutic approach for multiple sclerosis and other chronic inflammatory diseases of the CNS.

Endocrine, metabolic & immune disorders drug targets 20080601

Phase II enzyme induction by alpha-lipoic acid through phosphatidylinositol 3-kinase-dependent C/EBPs activation.

Xenobiotica; the fate of foreign compounds in biological systems 20080601

[An endogenous dithiol with antioxidant properties: alpha-lipoic acid, potential uses in cardiovascular diseases].

Annales de cardiologie et d'angeiologie 20080601

Beneficial effect of alpha-lipoic acid on lipopolysaccharide-induced oxidative stress in bronchoalveolar lavage fluid.

Journal of physiology and pharmacology : an official journal of the Polish Physiological Society 20080601

Coenzyme Q(10) and alpha-lipoic acid supplementation in diabetic rats: conduction velocity distributions.

Methods and findings in experimental and clinical pharmacology 20080601

The combination of alpha-lipoic acid supplementation and aerobic exercise inhibits lipid peroxidation in rat skeletal muscles.

Nutrition research (New York, N.Y.) 20080601

Alpha-lipoic acid induces apoptosis in hepatoma cells via the PTEN/Akt pathway.

FEBS letters 20080528

Electrochemical characterization of pore formation by bacterial protein toxins on hybrid supported membranes.

Langmuir : the ACS journal of surfaces and colloids 20080520

Irrigation with diluted seawater improves the nutritional value of cherry tomatoes.

Journal of agricultural and food chemistry 20080514

Increased biomass yield of Lactococcus lactis during energetically limited growth and respiratory conditions.

Biotechnology and applied biochemistry 20080501

Potent upregulation of glutathione and NAD(P)H:quinone oxidoreductase 1 by alpha-lipoic acid in human neuroblastoma SH-SY5Y cells: protection against neurotoxicant-elicited cytotoxicity.

Neurochemical research 20080501

The antioxidant alpha-lipoic acid improves endothelial dysfunction induced by acute hyperglycaemia during OGTT in impaired glucose tolerance.

Clinical endocrinology 20080501

Treatment of experimental autoimmune encephalomyelitis with alpha lipoic acid and associative conditioning.

Brain, behavior, and immunity 20080501

High glucose-induced NF-kappaB activation occurs via tyrosine phosphorylation of IkappaBalpha in human glomerular endothelial cells: involvement of Syk tyrosine kinase.

American journal of physiology. Renal physiology 20080501

Oxaliplatin acts on IB4-positive nociceptors to induce an oxidative stress-dependent acute painful peripheral neuropathy.

The journal of pain : official journal of the American Pain Society 20080501

Antioxidants preserve redox balance and inhibit c-Jun-N-terminal kinase pathway while improving insulin signaling in fat-fed rats: evidence for the role of oxidative stress on IRS-1 serine phosphorylation and insulin resistance.

The Journal of endocrinology 20080501

Physiological and molecular adaptations to drought in Andean potato genotypes.

Journal of experimental botany 20080501

[Estimation of protective effect of lipoic acid in the brain of rats during lipopolysaccharide-induced oxidative stress].

Polski merkuriusz lekarski : organ Polskiego Towarzystwa Lekarskiego 20080501

Alpha-lipoic acid suppresses 6-hydroxydopamine-induced ROS generation and apoptosis through the stimulation of glutathione synthesis but not by the expression of heme oxygenase-1.

Brain research 20080424

Design, synthesis and pharmacological evaluation of hybrid molecules out of quinazolinimines and lipoic acid lead to highly potent and selective butyrylcholinesterase inhibitors with antioxidant properties.

Bioorganic & medicinal chemistry 20080415

Antioxidants prevent ethanol-associated apoptosis in fetal rhombencephalic neurons.

Brain research 20080414

Induction of oxidative stress as a mechanism of action of chemopreventive agents against cancer.

British journal of cancer 20080408

Is dihydrolipoic acid among the reductive activators of parasite CysHis proteases?

Experimental parasitology 20080401

Inhibitory effects of short-term administration of DL-alpha-lipoic acid on oxidative vulnerability induced by Abeta amyloid fibrils (25-35) in mice.

Molecular and cellular biochemistry 20080401

Lipoamide protects retinal pigment epithelial cells from oxidative stress and mitochondrial dysfunction.

Free radical biology & medicine 20080401

Randomized phase III clinical trial of five different arms of treatment for patients with cancer cachexia: interim results.

Nutrition (Burbank, Los Angeles County, Calif.) 20080401

Lipoic acid significantly restores, in rats, the age-related decline in vasomotion.

British journal of pharmacology 20080401

A preliminary investigation of alpha-lipoic acid treatment of antipsychotic drug-induced weight gain in patients with schizophrenia.

Journal of clinical psychopharmacology 20080401

Lipoic acid supplementation and endothelial function.

British journal of pharmacology 20080401

Dietary antioxidants protect hematopoietic cells and improve animal survival after total-body irradiation.

Radiation research 20080401

Synthesis and cytotoxic activity of diosgenyl saponin analogues.

Bioorganic & medicinal chemistry 20080315

Glucose-6-phosphate dehydrogenase deficiency enhances human coronavirus 229E infection.

The Journal of infectious diseases 20080315

Memory impairment, oxidative damage and apoptosis induced by space radiation: ameliorative potential of alpha-lipoic acid.

Behavioural brain research 20080305

The 3-hydroxyacyl-ACP dehydratase of mitochondrial fatty acid synthesis in Trypanosoma brucei.

FEBS letters 20080305

Effects of alpha-lipoic acid on endothelial function in aged diabetic and high-fat fed rats.

British journal of pharmacology 20080301

Alpha-lipoic acid protects against renal ischaemia-reperfusion injury in rats.

Clinical and experimental pharmacology & physiology 20080301

Lipoic acid ameliorates oxidative stress and renal injury in alloxan diabetic rabbits.

Biochimie 20080301

Oxidant generation predominates around calcifying foci and enhances progression of aortic valve calcification.

Arteriosclerosis, thrombosis, and vascular biology 20080301

Restoration of blood total glutathione status and lymphocyte function following alpha-lipoic acid supplementation in patients with HIV infection.

Journal of alternative and complementary medicine (New York, N.Y.) 20080301

Effect of the antioxidant alpha-lipoic acid on apoptosis in human umbilical vein endothelial cells induced by high glucose.

Clinical and experimental medicine 20080301

Postmitotic tissue selenium and manganese levels in alpha-lipoic acid-supplemented aged rats.

Chemico-biological interactions 20080215

Novel lipoate-selective membrane sensor for the flow injection determination of alpha-lipoic acid in pharmaceutical preparations and urine.

Talanta 20080215

Diabetic neuropathy: new strategies for treatment.

Diabetes, obesity & metabolism 20080201

Genetic and pharmacologic manipulation of oxidative stress after neonatal hypoxia-ischemia.

International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience 20080201

Participation of chlorobiumquinone in the transplasma membrane electron transport system of Leishmania donovani promastigote: effect of near-ultraviolet light on the redox reaction of plasma membrane.

Biochimica et biophysica acta 20080201

Effect of vitamin C and lipoic acid on streptozotocin-induced diabetes gene expression: mRNA and protein expressions of Cu-Zn SOD and catalase.

Molecular and cellular biochemistry 20080201

alpha-Lipoic acid and ascorbate prevent LDL oxidation and oxidant stress in endothelial cells.

Molecular and cellular biochemistry 20080201

Electroconductive and photocurrent generation properties of self-assembled monolayers formed by functionalized, conformationally-constrained peptides on gold electrodes.

Journal of peptide science : an official publication of the European Peptide Society 20080201

Alpha lipoic acid attenuates microvascular endothelial cell hyperpermeability by inhibiting the intrinsic apoptotic signaling.

American journal of surgery 20080201

Lipoic acid suppression of neutrophil respiratory burst: effect of NADPH.

Antioxidants & redox signaling 20080201

Alpha-lipoic acid inhibits TNF-alpha induced NF-kappa B activation through blocking of MEKK1-MKK4-IKK signaling cascades.

International immunopharmacology 20080201

Treatment of diabetic neuropathy and neuropathic pain: how far have we come?

Diabetes care 20080201

The significance of Nrf2 pathway in (photo)-oxidative stress response in melanocytes and keratinocytes of the human epidermis.

Pigment cell & melanoma research 20080201

Protective effect of lipoic acid against methylglyoxal-induced oxidative stress in LLC-PK(1) cells.

Journal of nutritional science and vitaminology 20080201

Endothelial effects of antihypertensive treatment: focus on irbesartan.

Vascular health and risk management 20080201

Dietary alpha-lipoic acid supplementation inhibits atherosclerotic lesion development in apolipoprotein E-deficient and apolipoprotein E/low-density lipoprotein receptor-deficient mice.

Circulation 20080122

The potential protective role of alpha-lipoic acid against acetaminophen-induced hepatic and renal damage.

Toxicology 20080120

The role of loop and beta-turn residues as structural and functional determinants for the lipoyl domain from the Escherichia coli 2-oxoglutarate dehydrogenase complex.

The Biochemical journal 20080115

Design and synthesis of cellulose derivatives with antioxidant activity.

Macromolecular bioscience 20080109

Reversible inhibition of alpha-ketoglutarate dehydrogenase by hydrogen peroxide: glutathionylation and protection of lipoic acid.

Biochemistry 20080108

Insulin signaling and the heat shock response modulate protein homeostasis in the Caenorhabditis elegans intestine during infection.

The Journal of biological chemistry 20080104

Antioxidants modulate the IL-6 induced inhibition of negative acute-phase protein secretion in HepG2 cells.

Cell biochemistry and function 20080101

The effects and mechanisms of mitochondrial nutrient alpha-lipoic acid on improving age-associated mitochondrial and cognitive dysfunction: an overview.

Neurochemical research 20080101

Alpha-lipoic acid promotes the growth of rat hepatic pre-neoplastic lesions in the choline-deficient model.

Carcinogenesis 20080101

Vascular and neural dysfunction in Zucker diabetic fatty rats: a difficult condition to reverse.

Diabetes, obesity & metabolism 20080101

Antioxidant effect of alpha-lipoic acid against ethanol-induced gastric mucosal erosion in rats.

Pharmacology 20080101

R-alpha-lipoic acid and acetyl-L-carnitine complementarily promote mitochondrial biogenesis in murine 3T3-L1 adipocytes.

Diabetologia 20080101

Effects of alpha-lipoic acid on ischemia-reperfusion-induced renal dysfunction in rats.

American journal of physiology. Renal physiology 20080101

Streptococcus pneumoniae: proteomics of surface proteins for vaccine development.

Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases 20080101

The effect of lipoic acid on antioxidant status and lipid peroxidation in rats exposed to chronic restraint stress.

Physiological research 20080101

Structurally colored thiol chitosan thin films as a platform for aqueous heavy metal ion detection.

Biomacromolecules 20080101

alpha-Lipoic acid modulates extracellular matrix and angiogenesis gene expression in non-healing wounds treated with hyperbaric oxygen therapy.

Molecular medicine (Cambridge, Mass.) 20080101

Burning mouth syndrome and burning mouth in hypothyroidism: proposal for a diagnostic and therapeutic protocol.

Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics 20080101

Primary antioxidant free radical scavenging and redox signaling pathways in higher plant cells.

International journal of biological sciences 20080101

Genetic evidence for a mitochondriate ancestry in the 'amitochondriate' flagellate Trimastix pyriformis.

PloS one 20080101

In vitro and in vivo anti-oxidant activity of hot water extract of basidiomycetes-X, newly identified edible fungus.

Biological & pharmaceutical bulletin 20080101

The effect of alpha-lipoic acid on NOS dispersion in the lung of streptozotocin-induced diabetic rats.

Journal of diabetes and its complications 20080101

Primary biliary cirrhosis.

Orphanet journal of rare diseases 20080101

Bench-to-bedside review: The inflammation-perpetuating pattern-recognition receptor RAGE as a therapeutic target in sepsis.

Critical care (London, England) 20080101

Pyrroloquinoline Quinone (PQQ) Prevents Cognitive Deficit Caused by Oxidative Stress in Rats.

Journal of clinical biochemistry and nutrition 20080101

alpha-Lipoic acid: the potential for use in cancer therapy.

Neoplasma 20080101

Lipoic acid and acetyl-carnitine reverse iron-induced oxidative stress in human fibroblasts.

Redox report : communications in free radical research 20080101

Effects of lipoic acid on citrate content, aconitate hydratase activity, and oxidative status during myocardial ischemia in rats.

Biochemistry. Biokhimiia 20080101

Symptoms of somatization as a rapid screening tool for mitochondrial dysfunction in depression.

BioPsychoSocial medicine 20080101

Epigallocatechin gallate protects against oxidative stress-induced mitochondria-dependent apoptosis in human lens epithelial cells.

Molecular vision 20080101

Exercise training with dietary counselling increases mitochondrial chaperone expression in middle-aged subjects with impaired glucose tolerance.

BMC endocrine disorders 20080101

Prevention of Oxidative Stress-Induced Retinal Pigment Epithelial Cell Death by the PPARgamma Agonists, 15-Deoxy-Delta 12, 14-Prostaglandin J(2).

PPAR research 20080101

Cell death by SecTRAPs: thioredoxin reductase as a prooxidant killer of cells.

PloS one 20080101

Painful diabetic neuropathy: treatment and future aspects.

Diabetes/metabolism research and reviews 20080101

[Implication of alpha-lipoic acid preparations in the treatment of diabetic neuropathy].

Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova 20080101

[Assessment of berlition effectiveness in ischemic stroke with CT perfusion imaging of the brain].

Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova 20080101

Effect of HIV-1-related protein expression on cardiac and skeletal muscles from transgenic rats.

AIDS research and therapy 20080101

Biological actions of lipoic acid associated with sulfane sulfur metabolism.

Pharmacological reports : PR 20080101

A combination of nutriments improves mitochondrial biogenesis and function in skeletal muscle of type 2 diabetic Goto-Kakizaki rats.

PloS one 20080101

A low dose of dietary resveratrol partially mimics caloric restriction and retards aging parameters in mice.

PloS one 20080101

Cardiac autonomic activity and blood pressure among Nunavik Inuit adults exposed to environmental mercury: a cross-sectional study.

Environmental health : a global access science source 20080101

[Pharmacological significance of alpha lipoic acid in up to date treatment of diabetic neuropathy].

Medicinski arhiv 20080101

Knockdown of cytosolic glutaredoxin 1 leads to loss of mitochondrial membrane potential: implication in neurodegenerative diseases.

PloS one 20080101

Depletion of Plasmodium berghei plasmoredoxin reveals a non-essential role for life cycle progression of the malaria parasite.

PloS one 20080101

Regulation of cell cycle transition and induction of apoptosis in HL-60 leukemia cells by lipoic acid: role in cancer prevention and therapy.

Journal of hematology & oncology 20080101

[The free-radical processes and antioxidant therapy in brain ischemia].

Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova 20080101

[Alpha-tocopherol and alpha-lipoic acid. An antioxidant synergy with potential for preventive medicine].

Revista de investigacion clinica; organo del Hospital de Enfermedades de la Nutricion 20080101

[Postprandial hyperglycemia as a risk factor in the development of endothelial dysfunction--how to prevent?].

Lijecnicki vjesnik 20080101

Complete genome sequence of the extremely acidophilic methanotroph isolate V4, Methylacidiphilum infernorum, a representative of the bacterial phylum Verrucomicrobia.

Biology direct 20080101

Thioctic acid and acetyl-L-carnitine in the treatment of sciatic pain caused by a herniated disc: a randomized, double-blind, comparative study.

Clinical drug investigation 20080101

Articulation of three core metabolic processes in Arabidopsis: fatty acid biosynthesis, leucine catabolism and starch metabolism.

BMC plant biology 20080101

The mitochondrial cocktail: rationale for combined nutraceutical therapy in mitochondrial cytopathies.

Advanced drug delivery reviews 20080101

[Effect of taurine and thioctacide on carbohydrate metabolism and the antioxydant system in rats with experimental diabetes].

Eksperimental'naia i klinicheskaia farmakologiia 20080101

Lipoic acid as an anti-inflammatory and neuroprotective treatment for Alzheimer's disease.

Advanced drug delivery reviews 20080101

[Oxidative stress and its effects on insulin resistance and pancreatic beta-cells dysfunction: relationship with type 2 diabetes mellitus complications].

Acta medica portuguesa 20080101

An engineered aryl azide ligase for site-specific mapping of protein-protein interactions through photo-cross-linking.

Angewandte Chemie (International ed. in English) 20080101

Anti-angiogenic effect of high doses of ascorbic acid.

Journal of translational medicine 20080101

[The use of dipyridamole (curantyl) in combination with alpha-lipoic acid in the treatment of diabetic neuropathy with retinopathy].

Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova 20080101

[The blood glutathione system in cerebral vascular diseases and its treatment with alpha-lipoic acid].

Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova 20080101

Pathogenesis of ganglion 'cell death' in glaucoma and neuroprotection: focus on ganglion cell axonal mitochondria.

Progress in brain research 20080101

Assessment of neuroprotection in the retina with DARC.

Progress in brain research 20080101

Assessment of protein set coherence using functional annotations.

BMC bioinformatics 20080101

Alpha-lipoic acid and ebselen prevent ischemia/reperfusion injury in the rat intestine.

Surgery today 20080101

[Changes in matrix metalloproteinases activities in normal and transformed mouse fibroblasts under effect of antioxidants].

Tsitologiia 20080101

Antioxidant and free radical scavenging activity of Spondias pinnata.

BMC complementary and alternative medicine 20080101

[Effect of alpha-lipoic acid and mexidol on neuro- and the affective status in patients at early stages of diabetic foot syndrome].

Klinicheskaia meditsina 20080101

Alpha--lipoic acid decreases DNA damage and oxidative stress induced by alcohol in the developing hippocampus and cerebellum of rat.

Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 20080101

Biochemical and Genetic Characterization of PspE and GlpE, Two Single-domain Sulfurtransferases of Escherichia coli.

The open microbiology journal 20080101

The effect of a low-carbohydrate, ketogenic diet versus a low-glycemic index diet on glycemic control in type 2 diabetes mellitus.

Nutrition & metabolism 20080101

[Mildronate effects on oxidant stress in type 2 diabetic patients with diabetic peripheral (sensomotor) neuropathy].

Terapevticheskii arkhiv 20080101

Antidepressants of the serotonin-antagonist type increase body fat and decrease lifespan of adult Caenorhabditis elegans.

PloS one 20080101

[Efficacy of using alpha-lipoic acid (berlition) in patients with nonalcoholic steatohepatitis].

Eksperimental'naia i klinicheskaia gastroenterologiia = Experimental & clinical gastroenterology 20080101

Lipoic acid and 6-formylpterin reduce potentiation of noise-induced hearing loss by carbon monoxide: preliminary investigation.

Journal of rehabilitation research and development 20080101

Antioxidant systems and oxidative stress in the testes.

Oxidative medicine and cellular longevity 20080101

Combined administration of taurine and monoisoamyl DMSA protects arsenic induced oxidative injury in rats.

Oxidative medicine and cellular longevity 20080101

The effect of biothiol on UV irradiated alpha-lipoic acid.

BioFactors (Oxford, England) 20080101

In silico toxicological screening of natural products.

Toxicology mechanisms and methods 20080101

Spinacia oleracea Modulates Radiation-Induced Biochemical Changes in Mice Testis.

Indian journal of pharmaceutical sciences 20080101

The role of vitamins and minerals in psychiatry.

Integrative medicine insights 20080101

IR spectroscopic studies of adsorption of dithiol-containing ligands on CdS nanocrystal films in aqueous solutions.

Langmuir : the ACS journal of surfaces and colloids 20071218

Detecting penicillin G in milk with impedimetric label-free immunosensor.

Biosensors & bioelectronics 20071215

Age-dependent upregulation of p53 and cytochrome c release and susceptibility to apoptosis in skeletal muscle fiber of aged rats: role of carnitine and lipoic acid.

Free radical biology & medicine 20071215

Interfacial activity of polymer-coated gold nanoparticles.

Langmuir : the ACS journal of surfaces and colloids 20071204

Antioxidants slow photoreceptor cell death in mouse models of retinitis pigmentosa.

Journal of cellular physiology 20071201

The effect of lipoic acid on lipid peroxidation and visual evoked potentials (VEPs) in rats exposed to chronic restraint stress.

The International journal of neuroscience 20071201

Involvement of kinin B1 receptor and oxidative stress in sensory abnormalities and arterial hypertension in an experimental rat model of insulin resistance.

Neuropeptides 20071201

The protective effect of alpha-lipoic acid in experimental ovarian ischaemia-reperfusion injury.

The Australian & New Zealand journal of obstetrics & gynaecology 20071201

Effect of cysteine derivatives administration in healthy men exposed to intense resistance exercise by evaluation of pro-antioxidant ratio.

The journal of physiological sciences : JPS 20071201

Inhibition of depurinating estrogen-DNA adduct formation by natural compounds.

Chemical research in toxicology 20071201

Possible relevance of HLA-DRB1*0403 haplotype in insulin autoimmune syndrome induced by alpha-lipoic acid, used as a dietary supplement.

Diabetes care 20071201

Nonvitamin, nonmineral dietary supplementation in HIV-positive people.

Nutrition in clinical practice : official publication of the American Society for Parenteral and Enteral Nutrition 20071201

Redirecting lipoic acid ligase for cell surface protein labeling with small-molecule probes.

Nature biotechnology 20071201

Apicoplast lipoic acid protein ligase B is not essential for Plasmodium falciparum.

PLoS pathogens 20071201

The plasma pharmacokinetics of R-(+)-lipoic acid administered as sodium R-(+)-lipoate to healthy human subjects.

Alternative medicine review : a journal of clinical therapeutic 20071201

Current concepts in targeted therapies for the pathophysiology of diabetic microvascular complications.

Vascular health and risk management 20071201

Antioxidant DL-alpha lipoic acid as an attenuator of adriamycin induced hepatotoxicity in rat model.

Indian journal of experimental biology 20071201

Management of painful diabetic neuropathy: what is new or in the pipeline for 2007?

Current diabetes reports 20071201

The bilberry blues.

Alternative medicine review : a journal of clinical therapeutic 20071201

alpha-Lipoic acid in dietary supplements: development and comparison of HPLC-CEAD and HPLC-ESI-MS methods.

Journal of pharmaceutical and biomedical analysis 20071130

Mechanism and substrate recognition of human holo ACP synthase.

Chemistry & biology 20071126

Thiol supplementation inhibits metalloproteinase activity independent of glutathione status.

Biochemical and biophysical research communications 20071123

Carnitine and lipoate ameliorates lipofuscin accumulation and monoamine oxidase activity in aged rat heart.

European journal of pharmacology 20071121

Enhancing the stability and biological functionalities of quantum dots via compact multifunctional ligands.

Journal of the American Chemical Society 20071114

Acetyl-L-carnitine and alpha-lipoic acid supplementation of aged beagle dogs improves learning in two landmark discrimination tests.

FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20071101

Effects of zinc on SN56 cholinergic neuroblastoma cells.

Journal of neurochemistry 20071101

Targeted binding of PLA microparticles with lipid-PEG-tethered ligands.

Biomaterials 20071101

Protective effect of lipoic acid on oxidative and peroxidative damage in cyclosporine A-induced renal toxicity.

International immunopharmacology 20071101

LplA1-dependent utilization of host lipoyl peptides enables Listeria cytosolic growth and virulence.

Molecular microbiology 20071101

Alpha-lipoic acid modulates gut inflammation induced by trinitrobenzene sulfonic acid in rats.

Journal of gastroenterology and hepatology 20071101

Diabetic nephropathy is associated with oxidative stress and decreased renal nitric oxide production.

Journal of the American Society of Nephrology : JASN 20071101

Antioxidants and narrow band-UVB in the treatment of vitiligo: a double-blind placebo controlled trial.

Clinical and experimental dermatology 20071101

Comparative crossover, randomized, open-label bioequivalence study on the bioequivalence of two formulations of thioctic acid in healthy volunteers.

Clinical and experimental hypertension (New York, N.Y. : 1993) 20071101

Blockade of oxidative stress by vitamin C ameliorates albuminuria and renal sclerosis in experimental diabetic rats.

Yonsei medical journal 20071031

[Curative effect of alpha-lipoic acid on peripheral neuropathy in type 2 diabetes: a clinical study].

Zhonghua yi xue za zhi 20071016

Improvement of patient tolerance to dapsone: current and future developments.

Dermatology online journal 20071013

Enzymatic characterization of dihydrolipoamide dehydrogenase from Streptococcus pneumoniae harboring its own substrate.

The Journal of biological chemistry 20071005

Dietary histone deacetylase inhibitors: from cells to mice to man.

Seminars in cancer biology 20071001

S-allylcysteine scavenges singlet oxygen and hypochlorous acid and protects LLC-PK(1) cells of potassium dichromate-induced toxicity.

Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20071001

Therapeutic efficacy of DL-alpha-lipoic acid on cyclosporine A induced renal alterations.

European journal of pharmacology 20071001

Vitamin transport and homeostasis in mammalian brain: focus on Vitamins B and E.

Journal of neurochemistry 20071001

Uptake and reduction of alpha-lipoic acid by human erythrocytes.

Clinical biochemistry 20071001

Ca2+/calmodulin-dependent protein kinase kinase is involved in AMP-activated protein kinase activation by alpha-lipoic acid in C2C12 myotubes.

American journal of physiology. Cell physiology 20071001

Protective effects of L-carnitine and alpha-lipoic acid in rats with adjuvant arthritis.

Pharmacological research 20071001

The 2-oxoacid dehydrogenase multi-enzyme complex of the archaeon Thermoplasma acidophilum - recombinant expression, assembly and characterization.

The FEBS journal 20071001

Impaired apparent ion demand in experimental diabetic retinopathy: correction by lipoic Acid.

Investigative ophthalmology & visual science 20071001

Iron-sulfur proteins as initiators of radical chemistry.

Natural product reports 20071001

[Safety and structural analysis of polymers produced in manufacturing process of alpha-lipoic acid].

Shokuhin eiseigaku zasshi. Journal of the Food Hygienic Society of Japan 20071001

A sensor for superoxide in aqueous and organic/aqueous media based on immobilized cytochrome c on binary self-assembled monolayers.

Biosensors & bioelectronics 20070930

Redox regulation of vitamin C transporter SVCT2 in C2C12 myotubes.

Biochemical and biophysical research communications 20070921

Intrinsic mitochondrial dysfunction in ATM-deficient lymphoblastoid cells.

Human molecular genetics 20070915

2-Styrylchromones: novel strong scavengers of reactive oxygen and nitrogen species.

Bioorganic & medicinal chemistry 20070915

Mitochondrial ageing and the beneficial role of alpha-lipoic acid.

Neurochemical research 20070901

The effect of alpha-lipoic acid on symptoms and skin blood flow in diabetic neuropathy.

Diabetic medicine : a journal of the British Diabetic Association 20070901

Alpha-lipoic acid increases cardiac glucose oxidation independent of AMP-activated protein kinase in isolated working rat hearts.

Basic research in cardiology 20070901

Cytochrome c oxidase rather than cytochrome c is a major determinant of mitochondrial respiratory capacity in skeletal muscle of aged rats: role of carnitine and lipoic acid.

Rejuvenation research 20070901

Comparative treatment of alpha-amanitin poisoning with N-acetylcysteine, benzylpenicillin, cimetidine, thioctic acid, and silybin in a murine model.

Annals of emergency medicine 20070901

R-(+)-alpha-lipoic acid inhibits endothelial cell apoptosis and proliferation: involvement of Akt and retinoblastoma protein/E2F-1.

American journal of physiology. Endocrinology and metabolism 20070901

Alpha-lipoic acid and insulin autoimmune syndrome.

Diabetes care 20070901

Mitochondrial protein lipoylation does not exclusively depend on the mtKAS pathway of de novo fatty acid synthesis in Arabidopsis.

Plant physiology 20070901

An open-label 52-week clinical extension comparing duloxetine with routine care in patients with diabetic peripheral neuropathic pain.

Pain medicine (Malden, Mass.) 20070901

A multipumping flow system for in vitro screening of peroxynitrite scavengers.

Journal of biomolecular screening 20070901

Sulfate assimilation in basal land plants - what does genomic sequencing tell us?

Plant biology (Stuttgart, Germany) 20070901

Lipoic acid and N-acetyl cysteine decrease mitochondrial-related oxidative stress in Alzheimer disease patient fibroblasts.

Journal of Alzheimer's disease : JAD 20070901

Protective effects of early treatment with lipoic acid in LPS-induced lung injury in rats.

Journal of physiology and pharmacology : an official journal of the Polish Physiological Society 20070901

The scientific impact of the Structural Genomics Consortium: a protein family and ligand-centered approach to medically-relevant human proteins.

Journal of structural and functional genomics 20070901

Induction of primary biliary cirrhosis in guinea pigs following chemical xenobiotic immunization.

Journal of immunology (Baltimore, Md. : 1950) 20070815

Crystal structure of bovine lipoyltransferase in complex with lipoyl-AMP.

Journal of molecular biology 20070803

Design and synthesis of 1,2-dithiolane derivatives and evaluation of their neuroprotective activity.

Bioorganic & medicinal chemistry letters 20070801

Not in the mind of neurasthenic lazybones but in the cell nucleus: patients with chronic fatigue syndrome have increased production of nuclear factor kappa beta.

Neuro endocrinology letters 20070801

Dual targeting of antioxidant and metabolic enzymes to the mitochondrion and the apicoplast of Toxoplasma gondii.

PLoS pathogens 20070801

Recognition of the inner lipoyl-bearing domain of dihydrolipoyl transacetylase and of the blood glucose-lowering compound AZD7545 by pyruvate dehydrogenase kinase 2.

Biochemistry 20070724

Protective effects of ischemic preconditioning and application of lipoic acid prior to 90 min of hepatic ischemia in a rat model.

World journal of gastroenterology 20070721

Crystal structure of pyruvate dehydrogenase phosphatase 1 and its functional implications.

Journal of molecular biology 20070713

Stable aqueous nanoparticle film assemblies with covalent and charged polymer linking networks.

Langmuir : the ACS journal of surfaces and colloids 20070703

Beneficial effect of DL-alpha-lipoic acid on cyclosporine A induced hyperlipidemic nephropathy in rats.

Molecular and cellular biochemistry 20070701

Activation of apoptosis signal regulating kinase 1 (ASK1) and translocation of death-associated protein, Daxx, in substantia nigra pars compacta in a mouse model of Parkinson's disease: protection by alpha-lipoic acid.

FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20070701

Oxidative stress reduces renal dopamine D1 receptor-Gq/11alpha G protein-phospholipase C signaling involving G protein-coupled receptor kinase 2.

American journal of physiology. Renal physiology 20070701

Simultaneous determination of alpha-lipoic acid and its reduced form by high-performance liquid chromatography with fluorescence detection.

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20070701

Reactive oxygen species mediate a cellular 'memory' of high glucose stress signalling.

Diabetologia 20070701

CoCl2 induces protective events via the p38-MAPK signalling pathway and ANP in the perfused amphibian heart.

The Journal of experimental biology 20070701

Pharmacodynamic effects of orally administered dexlipotam on endothelial function in type 2-diabetic patients.

International journal of clinical pharmacology and therapeutics 20070701

'Last supper with mushroom soup': a case report of amatoxin poisoning.

McGill journal of medicine : MJM : an international forum for the advancement of medical sciences by students 20070701

Transepithelial transport of alpha-lipoic acid across human intestinal Caco-2 cell monolayers.

Journal of agricultural and food chemistry 20070627

Targeting lipoic acid to mitochondria: synthesis and characterization of a triphenylphosphonium-conjugated alpha-lipoyl derivative.

Free radical biology & medicine 20070615

Alpha-lipoic acid differently affects the reserpine-induced oxidative stress in the striatum and prefrontal cortex of rat brain.

Neuroscience 20070608

Unusual fluorescence enhancement of a novel carbazolyldiacetylene bound to gold nanoparticles.

Langmuir : the ACS journal of surfaces and colloids 20070605

Redox changes induced in hippocampal precursor cells by heavy ion irradiation.

Radiation and environmental biophysics 20070601

Protection against arsenic trioxide-induced autophagic cell death in U118 human glioma cells by use of lipoic acid.

Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20070601

Dihydrolipoic acid inhibits skin tumor promotion through anti-inflammation and anti-oxidation.

Biochemical pharmacology 20070601

Mitochondrial acyl carrier proteins in Arabidopsis thaliana are predominantly soluble matrix proteins and none can be confirmed as subunits of respiratory Complex I.

Plant molecular biology 20070601

WRINKLED1 specifies the regulatory action of LEAFY COTYLEDON2 towards fatty acid metabolism during seed maturation in Arabidopsis.

The Plant journal : for cell and molecular biology 20070601

D-galactose toxicity in mice is associated with mitochondrial dysfunction: protecting effects of mitochondrial nutrient R-alpha-lipoic acid.

Biogerontology 20070601

Therapeutic effects of alpha-lipoic acid on bleomycin-induced pulmonary fibrosis in rats.

International journal of molecular medicine 20070601

Protection from hepatic ischemia/reperfusion injury and improvement of liver regeneration by alpha-lipoic acid.

Shock (Augusta, Ga.) 20070601

[Burning mouth syndrome].

Laryngo- rhino- otologie 20070601

The ArcA regulon and oxidative stress resistance in Haemophilus influenzae.

Molecular microbiology 20070601

Autophagocytosis of mitochondria is prominent in Alzheimer disease.

Journal of neuropathology and experimental neurology 20070601

Three case reports to illustrate clinical applications in the use of erythrocyte transketolase.

Evidence-based complementary and alternative medicine : eCAM 20070601

Thioredoxin glutathione reductase from Schistosoma mansoni: an essential parasite enzyme and a key drug target.

PLoS medicine 20070601

Chelation therapy and vanadium: effect on reproductive organs in rats.

Indian journal of experimental biology 20070601

Osteoporosis: integrating biomarkers and other diagnostic correlates into the management of bone fragility.

Alternative medicine review : a journal of clinical therapeutic 20070601

Effects of alpha-lipoic acid supplementation in peripheral arterial disease: a pilot study.

Journal of alternative and complementary medicine (New York, N.Y.) 20070601

Comparison of the total oxyradical scavenging capacity and oxygen radical absorbance capacity antioxidant assays.

Journal of medicinal food 20070601

Endothelial dysfunction in type 2 diabetes: effect of antioxidants.

Revista portuguesa de cardiologia : orgao oficial da Sociedade Portuguesa de Cardiologia = Portuguese journal of cardiology : an official journal of the Portuguese Society of Cardiology 20070601

Studies on free radicals, antioxidants, and co-factors.

Clinical interventions in aging 20070601

The role of thiols, dithiols, nutritional factors and interacting ligands in the toxicology of mercury.

Toxicology 20070520

Design and synthesis of novel quinolinone-3-aminoamides and their alpha-lipoic acid adducts as antioxidant and anti-inflammatory agents.

Journal of medicinal chemistry 20070517

Characterization of a lipoate-protein ligase A gene of rice (Oryza sativa L.).

Gene 20070515

Automatic in vitro determination of hypochlorous acid scavenging capacity exploiting multisyringe flow injection analysis and chemiluminescence.

Analytical chemistry 20070515

Biological assays and genomic analysis reveal lipoic acid modulation of endothelial cell behavior and gene expression.

Carcinogenesis 20070501

Efficacy of DL-alpha-lipoic acid on methanol induced free radical changes, protein oxidative damages and hsp70 expression in folate deficient rat nervous tissue.

Chemico-biological interactions 20070501

Effect of DL-alpha-lipoic acid on cyclophosphamide induced lysosomal changes in oxidative cardiotoxicity.

Life sciences 20070501

Fluorimetric determination of some sulfur containing compounds through complex formation with terbium (Tb+3) and uranium (U+3).

Journal of fluorescence 20070501

The role of plant mitochondria in the biosynthesis of coenzymes.

Photosynthesis research 20070501

Alpha-lipoic acid may improve symptomatic diabetic polyneuropathy.

The neurologist 20070501

Effect of alpha-lipoic acid supplementation on trace element levels in serum and in postmitotic tissue in aged rats.

Medicinal chemistry (Shariqah (United Arab Emirates)) 20070501

[Glucose transponer type 1 deficiency síndrome (GLUT-1 SD) treated with ketogenic diet. Report of one case].

Revista medica de Chile 20070501

Indian herbs and herbal drugs used for the treatment of diabetes.

Journal of clinical biochemistry and nutrition 20070501

Arsenic and lead induced free radical generation and their reversibility following chelation.

Cellular and molecular biology (Noisy-le-Grand, France) 20070415

Traces of copper ions deplete glutathione in human hepatoma cell cultures with low cysteine content.

Chemico-biological interactions 20070405

Properties of recombinant glycine decarboxylase P- and H-protein subunits from the cyanobacterium Synechocystis sp. strain PCC 6803.

FEBS letters 20070403

Involvement of oxidants and AP-1 in angiotensin II-activated NFAT3 transcription factor.

American journal of physiology. Cell physiology 20070401

Alpha-lipoic Acid modulates heat shock factor-1 expression in streptozotocin-induced diabetic rat kidney.

Antioxidants & redox signaling 20070401

Histochemical staining and quantification of dihydrolipoamide dehydrogenase diaphorase activity using blue native PAGE.

Electrophoresis 20070401

Effect of combined treatment with alpha-Lipoic acid and acetyl-L-carnitine on vascular function and blood pressure in patients with coronary artery disease.

Journal of clinical hypertension (Greenwich, Conn.) 20070401

More light please.

Journal of clinical hypertension (Greenwich, Conn.) 20070401

[High-performance liquid chromatography for determining plasma alpha-lipoic acid in New Zealand rabbits].

Nan fang yi ke da xue xue bao = Journal of Southern Medical University 20070401

Arsenic induced oxidative stress and the role of antioxidant supplementation during chelation: a review.

Journal of environmental biology 20070401

The influence of diluted seawater and ripening stage on the content of antioxidants in fruits of different tomato genotypes.

Journal of agricultural and food chemistry 20070321

Lipoic acid stimulates cAMP production in T lymphocytes and NK cells.

Biochemical and biophysical research communications 20070302

Possible relevance of alpha lipoic acid contained in a health supplement in a case of insulin autoimmune syndrome.

Diabetes research and clinical practice 20070301

alpha-Lipoic acid attenuates x-irradiation-induced oxidative stress in mice.

Cell biology and toxicology 20070301

Exercise-induced brachial artery vasodilation: role of free radicals.

American journal of physiology. Heart and circulatory physiology 20070301

Is there a role for reactive oxygen species in arterial medial elastocalcinosis?

Vascular pharmacology 20070301

Effects of PGC-1alpha on TNF-alpha-induced MCP-1 and VCAM-1 expression and NF-kappaB activation in human aortic smooth muscle and endothelial cells.

Antioxidants & redox signaling 20070301

Mitogen-activated protein kinase upregulation reduces renal D1 receptor affinity and G-protein coupling in obese rats.

Kidney international 20070301

Modulating effects of a novel skin-lightening agent, alpha-lipoic acid derivative, on melanin production by the formation of DOPA conjugate products.

Bioorganic & medicinal chemistry 20070301

New noncellular fluorescence microplate screening assay for scavenging activity against singlet oxygen.

Analytical and bioanalytical chemistry 20070301

Scavenging of the cofactor lipoate is essential for the survival of the malaria parasite Plasmodium falciparum.

Molecular microbiology 20070301

Alpha-lipoic acid: physiologic mechanisms and indications for the treatment of metabolic syndrome.

Expert opinion on investigational drugs 20070301

Continuous infusion of lipoic acid rapidly reduces plasma beta-hydroxybutyrate with elevation of non-esterified fatty acids in broiler chickens.

The British journal of nutrition 20070301

[Role of 5-HT2A-receptors coupled with superoxide anion in the medial area of nucleus retrofacialis].

Nan fang yi ke da xue xue bao = Journal of Southern Medical University 20070301

Alpha-lipoic acid as a directly binding activator of the insulin receptor: protection from hepatocyte apoptosis.

Biochemistry 20070227

Alpha-lipoic acid inhibits matrix metalloproteinase-9 expression by inhibiting NF-kappaB transcriptional activity.

Experimental & molecular medicine 20070227

Mitochondrial fatty acid synthesis in Trypanosoma brucei.

The Journal of biological chemistry 20070216

Monolayer-protected gold nanoparticles by the self-assembly of micellar poly(ethylene oxide)-b-poly(epsilon-caprolactone) block copolymer.

Langmuir : the ACS journal of surfaces and colloids 20070213

Radiation-induced cognitive dysfunction and cerebellar oxidative stress in mice: protective effect of alpha-lipoic acid.

Behavioural brain research 20070212

Distinct modes of recognition of the lipoyl domain as substrate by the E1 and E3 components of the pyruvate dehydrogenase multienzyme complex.

Journal of molecular biology 20070209

Chronic dietary alpha-lipoic acid reduces deficits in hippocampal memory of aged Tg2576 mice.

Neurobiology of aging 20070201

S-adenosylmethionine and radical-based catalysis.

Amino acids 20070201

Beneficial effects of creatine, CoQ10, and lipoic acid in mitochondrial disorders.

Muscle & nerve 20070201

alpha-Lipoic acid and glutathione protect against the prooxidant activity of SOD/catalase mimetic manganese salen derivatives.

Journal of inorganic biochemistry 20070201

Receptor for advanced glycation end products activation injures primary sensory neurons via oxidative stress.

Endocrinology 20070201

Effects of chemical chaperones on oxidative stress and detergent-insoluble species formation following conditional expression of amyloid precursor protein carboxy-terminal fragment.

Neurobiology of disease 20070201

Vitamin A potently destabilizes preformed alpha-synuclein fibrils in vitro: implications for Lewy body diseases.

Neurobiology of disease 20070201

Mitigation of age-dependent oxidative damage to DNA in rat heart by carnitine and lipoic acid.

Mechanisms of ageing and development 20070201

Involvement of PI3K/PKG/ERK1/2 signaling pathways in cortical neurons to trigger protection by cotreatment of acetyl-L-carnitine and alpha-lipoic acid against HNE-mediated oxidative stress and neurotoxicity: implications for Alzheimer's disease.

Free radical biology & medicine 20070201

Extending the dynamic range of electrochemical sensors using multiple modified electrodes.

Analytical and bioanalytical chemistry 20070201

Structure of the human beta-ketoacyl [ACP] synthase from the mitochondrial type II fatty acid synthase.

Protein science : a publication of the Protein Society 20070201

Effects of lipoic acid and dihydrolipoic acid on total erythrocytic thiols under conditions of restricted glucose in vitro.

Basic & clinical pharmacology & toxicology 20070201

Modulation of p38 mitogen-activated protein kinase cascade and metalloproteinase activity in diaphragm muscle in response to free radical scavenger administration in dystrophin-deficient Mdx mice.

The American journal of pathology 20070201

An approach to elucidate potential mechanism of renal toxicity of arsenic trioxide.

Experimental hematology 20070201

Changes of terminal cancer patients' health-related quality of life after high dose vitamin C administration.

Journal of Korean medical science 20070201

[Burning mouth syndrome].

Recenti progressi in medicina 20070201

Lipoate-based imprinted self-assembled molecular thin films for biosensor applications.

Biosensors & bioelectronics 20070115

Oriented immobilization of antibodies with GST-fused multiple Fc-specific B-domains on a gold surface.

Analytical chemistry 20070115

Role of reduced lipoic acid in the redox regulation of mitochondrial aldehyde dehydrogenase (ALDH-2) activity. Implications for mitochondrial oxidative stress and nitrate tolerance.

The Journal of biological chemistry 20070105

Hexosamine induction of oxidative stress, hypertrophy and laminin expression in renal mesangial cells: effect of the anti-oxidant alpha-lipoic acid.

Cell biochemistry and function 20070101

Alpha-lipoic acid suppresses the development of collagen-induced arthritis and protects against bone destruction in mice.

Rheumatology international 20070101

Presynaptic mechanisms underlying the alpha-lipoic acid facilitation of glutamate exocytosis in rat cerebral cortex nerve terminals.

Neurochemistry international 20070101

Lipoic acid as a novel treatment for Alzheimer's disease and related dementias.

Pharmacology & therapeutics 20070101

Inhibition of cystathionine-gamma-lyase leads to loss of glutathione and aggravation of mitochondrial dysfunction mediated by excitatory amino acid in the CNS.

Neurochemistry international 20070101

Protective effect of alpha-lipoic acid in experimental spermatic cord torsion.

Nutrition (Burbank, Los Angeles County, Calif.) 20070101

Should it be safer to use a redox couple, both with (R)-alpha-lipoic acid combined with (R)-dihydrolipoic acid for avoiding prooxidant action of alpha-lipoic acid?

Medical hypotheses 20070101

Increased ROS generation and p53 activation in alpha-lipoic acid-induced apoptosis of hepatoma cells.

Apoptosis : an international journal on programmed cell death 20070101

Acrolein, a toxicant in cigarette smoke, causes oxidative damage and mitochondrial dysfunction in RPE cells: protection by (R)-alpha-lipoic acid.

Investigative ophthalmology & visual science 20070101

Effect of noise on microvascular integrity in laboratory rats.

Journal of the American Association for Laboratory Animal Science : JAALAS 20070101

Radioprotectant screening for cryocrystallography.

Journal of synchrotron radiation 20070101

Self-assembled monolayers with latent aldehydes for protein immobilization.

Bioconjugate chemistry 20070101

A long-term 'memory' of HIF induction in response to chronic mild decreased oxygen after oxygen normalization.

BMC cardiovascular disorders 20070101

Effects of alpha-lipoic acid on the plasma levels of asymmetric dimethylarginine in diabetic end-stage renal disease patients on hemodialysis: a pilot study.

American journal of nephrology 20070101

Alpha-lipoic acid protects against hepatic ischemia-reperfusion injury in rats.

Pharmacology 20070101

Efficacy and safety of alpha-lipoic acid supplementation in the treatment of symptomatic diabetic neuropathy.

The Diabetes educator 20070101

Efficacy of alpha-lipoic acid against diabetic cataract in rat.

Japanese journal of ophthalmology 20070101

Algorithm for complementary and alternative medicine practice and research in type 2 diabetes.

Journal of alternative and complementary medicine (New York, N.Y.) 20070101

Long term highly saturated fat diet does not induce NASH in Wistar rats.

Nutrition & metabolism 20070101

Insulin Autoimmune Syndrome possibly caused by alpha lipoic acid.

Internal medicine (Tokyo, Japan) 20070101

A randomized double-blind placebo-controlled trial of thioctic acid in migraine prophylaxis.

Headache 20070101

Effects of curcumin on retinal oxidative stress and inflammation in diabetes.

Nutrition & metabolism 20070101

Alpha-lipoic acid may be a clinically useful therapy in interstitial cystitis.

Medical hypotheses 20070101

Diversifying selection and host adaptation in two endosymbiont genomes.

BMC evolutionary biology 20070101

Using gene expression data and network topology to detect substantial pathways, clusters and switches during oxygen deprivation of Escherichia coli.

BMC bioinformatics 20070101

Supplement use in sport: is there a potentially dangerous incongruence between rationale and practice?

Journal of occupational medicine and toxicology (London, England) 20070101

Normalisation of multicondition cDNA macroarray data.

Comparative and functional genomics 20070101

Screening candidate longevity therapeutics using gene-expression arrays.

Gerontology 20070101

Profiling of chicken adipose tissue gene expression by genome array.

BMC genomics 20070101

The clinical application of metabolic therapy for cardiovascular disease.

Heart, lung & circulation 20070101

Hepatocellular injury of nonischemic liver tissue after selective clamping in rats--protective action by pharmacological pretreatment with lipoic acid.

European surgical research. Europaische chirurgische Forschung. Recherches chirurgicales europeennes 20070101

[Thioctic acid action on glutathione-dependent antioxidant system functioning at toxic hepatitis of rats].

Biomeditsinskaia khimiia 20070101

Oxidative stress and diabetic retinopathy.

Experimental diabetes research 20070101

Intramyocellular lipid kinetics and insulin resistance.

Lipids in health and disease 20070101

Chronic administration of R-flurbiprofen attenuates learning impairments in transgenic amyloid precursor protein mice.

BMC neuroscience 20070101

The tricarboxylic acid cycle, an ancient metabolic network with a novel twist.

PloS one 20070101

[Liver cirrhosis and therapy issues].

Likars'ka sprava 20070101

Thioredoxin reductase is a key factor in the oxidative stress response of Lactobacillus plantarum WCFS1.

Microbial cell factories 20070101

Increased autophagic degradation of mitochondria in Alzheimer disease.

Autophagy 20070101

The novel agent, alpha lipoic acid, can cause the development of insulin autoimmune syndrome.

Internal medicine (Tokyo, Japan) 20070101

Role of advanced glycation end products in hypertension and atherosclerosis: therapeutic implications.

Cell biochemistry and biophysics 20070101

Creatine monohydrate and conjugated linoleic acid improve strength and body composition following resistance exercise in older adults.

PloS one 20070101

Alpha-lipoic acid as a new treatment option for Alzheimer's disease--a 48 months follow-up analysis.

Journal of neural transmission. Supplementum 20070101

Are we getting enough sulfur in our diet?

Nutrition & metabolism 20070101

Biological variability dominates and influences analytical variance in HPLC-ECD studies of the human plasma metabolome.

BMC clinical pathology 20070101

Effect of surface conjugation chemistry on the sensitivity of microcantilever sensors.

Scanning 20070101

Sulfur mustard toxicity following dermal exposure: role of oxidative stress, and antioxidant therapy.

Journal of burns and wounds 20070101

Contributions of inflammatory processes to the development of the early stages of diabetic retinopathy.

Experimental diabetes research 20070101

Design of biotin-functionalized luminescent quantum dots.

Journal of biomedicine & biotechnology 20070101

[Study of hepatoprotective activity of ethylmethylhydroxypyridine fumarate and lipoate in the experimental toxic hepatitis].

Eksperimental'naia i klinicheskaia gastroenterologiia = Experimental & clinical gastroenterology 20070101

Effect of moderately high dietary salt and lipoic acid on blood pressure in Wistar-Kyoto rats.

Experimental and clinical cardiology 20070101

Alpha-lipoic acid: an inhibitor of secretory phospholipase A2 with anti-inflammatory activity.

Life sciences 20061214

A synchronized substrate-gating mechanism revealed by cubic-core structure of the bovine branched-chain alpha-ketoacid dehydrogenase complex.

The EMBO journal 20061213

Determination of specific activities and kinetic constants of biotinidase and lipoamidase in LEW rat and Lactobacillus casei (Shirota).

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20061205

Self-assembly of C(60) pi-extended tetrathiafulvalene (exTTF) dyads on gold surfaces.

Langmuir : the ACS journal of surfaces and colloids 20061205

Long-term safety of alpha-lipoic acid (ALA) consumption: A 2-year study.

Regulatory toxicology and pharmacology : RTP 20061201

Reactive oxygen species mediate caspase activation and apoptosis induced by lipoic acid in human lung epithelial cancer cells through Bcl-2 down-regulation.

The Journal of pharmacology and experimental therapeutics 20061201

Diet supplementation for 5 weeks with polyphenol-rich cereals improves several functions and the redox state of mouse leucocytes.

European journal of nutrition 20061201

Preliminary evidence on existence of transplasma membrane electron transport in Entamoeba histolytica trophozoites: a key mechanism for maintaining optimal redox balance.

Journal of bioenergetics and biomembranes 20061201

Structural and thermodynamic studies of simple aldose reductase-inhibitor complexes.

Bioorganic chemistry 20061201

Paraquat-induced oxidative stress in drosophila melanogaster: effects of melatonin, glutathione, serotonin, minocycline, lipoic acid and ascorbic acid.

Neurochemical research 20061201

Bioavailability of selenium from the selenotrisulphide derivative of lipoic acid.

Photodermatology, photoimmunology & photomedicine 20061201

Peripheral neuropathy: pathogenic mechanisms and alternative therapies.

Alternative medicine review : a journal of clinical therapeutic 20061201

T cell targeting and phagocytosis of apoptotic biliary epithelial cells in primary biliary cirrhosis.

Journal of autoimmunity 20061201

Effects of glutathione and N-acetyl cysteine on the antimycobacterial efficacy of isoniazid on Mycobacterium fortuitum in vitro.

Journal of chemotherapy (Florence, Italy) 20061201

[Beneficial actions of lipoic acid in cerebral cortex homogenates in rats during lipopolysaccharide-induced oxidative stress].

Polski merkuriusz lekarski : organ Polskiego Towarzystwa Lekarskiego 20061201

Multitarget-directed drug design strategy: a novel molecule designed to block epidermal growth factor receptor (EGFR) and to exert proapoptotic effects.

Journal of medicinal chemistry 20061116

Reduction of ischemia reperfusion injury after liver resection and hepatic inflow occlusion by alpha-lipoic acid in humans.

World journal of gastroenterology 20061114

Iron chelators reduce chromosomal breaks in ataxia-telangiectasia cells.

DNA repair 20061108

The effect of different antioxidants on glutathione turnover in human cell lines and their interaction with hydrogen peroxide.

Chemico-biological interactions 20061107

Interfacial pH and surface pKa of a thioctic acid self-assembled monolayer.

Physical chemistry chemical physics : PCCP 20061107

Alpha-lipoic acid inhibits fractalkine expression and prevents neointimal hyperplasia after balloon injury in rat carotid artery.

Atherosclerosis 20061101

Protective role of eicosapentaenoate-lipoate (EPA-LA) derivative in combating oxidative hepatocellular injury in hypercholesterolemic atherogenesis.

Atherosclerosis 20061101

Enzymatic activation of sulfur for incorporation into biomolecules in prokaryotes.

FEMS microbiology reviews 20061101

Oral treatment with alpha-lipoic acid improves symptomatic diabetic polyneuropathy: the SYDNEY 2 trial.

Diabetes care 20061101

Lipoic acid, a lead structure for multi-target-directed drugs for neurodegeneration.

Mini reviews in medicinal chemistry 20061101

Beneficial effect of supplemental lipoic acid on diabetes-induced pregnancy loss in the mouse.

Annals of the New York Academy of Sciences 20061101

Treatment of diabetic polyneuropathy: Update 2006.

Annals of the New York Academy of Sciences 20061101

Beneficial effects of natural antioxidants EGCG and alpha-lipoic acid on life span and age-dependent behavioral declines in Caenorhabditis elegans.

Pharmacology, biochemistry, and behavior 20061101

Doxorubicin-induced reactive oxygen species generation and intracellular Ca2+ increase are reciprocally modulated in rat cardiomyocytes.

Experimental & molecular medicine 20061031

Thioredoxin interacting protein is increased in sensory neurons in experimental diabetes.

Brain research 20061020

Alpha-lipoic acid modulates ovarian surface epithelial cell growth.

Gynecologic oncology 20061001

Role of lipoic acid in reducing the oxidative stress induced by cyclosporine A.

Clinica chimica acta; international journal of clinical chemistry 20061001

Antioxidant down-regulates interleukin-18 expression in asthma.

Molecular pharmacology 20061001

Safety evaluation of alpha-lipoic acid (ALA).

Regulatory toxicology and pharmacology : RTP 20061001

Modulation of transcription factor NF-kappaB in Hodgkin's lymphoma cell lines: effect of (-)-epicatechin.

Free radical research 20061001

Biotin uptake by rabbit corneal epithelial cells: role of sodium-dependent multivitamin transporter (SMVT).

Current eye research 20061001

Increased expression of heat shock protein 72 protects renal proximal tubular cells from gentamicin-induced injury.

Journal of Korean medical science 20061001

Synthesis, pulse radiolysis, and in vitro radioprotection studies of melatoninolipoamide, a novel conjugate of melatonin and alpha-lipoic acid.

Bioorganic & medicinal chemistry 20060915

Dietary antioxidants and behavioral enrichment enhance neutrophil phagocytosis in geriatric Beagles.

Veterinary immunology and immunopathology 20060915

Insight into the role of DL-alpha-lipoic acid against cyclophosphamide induced alterations in calcium sensitivity of cardiac myofilaments.

Molecular and cellular biochemistry 20060901

Effect of chronic restraint stress and alpha-lipoic acid on lipid peroxidation and antioxidant enzyme activities in rat peripheral organs.

Pharmacological research 20060901

Effects of lipoic acid and dihydrolipoic acid on 4-aminophenol-mediated erythrocytic toxicity in vitro.

Basic & clinical pharmacology & toxicology 20060901

alpha-lipoic acid corrects late-phase supernormal retinal oxygenation response in experimental diabetic retinopathy.

Investigative ophthalmology & visual science 20060901

Twenty paces from history: an interview with Soraya de Chadarevian by Jane Gitschier.

PLoS genetics 20060901

Application of N-PLS calibration to the simultaneous determination of Cu(2+), Cd(2+) and Pb(2+) using peptide modified electrochemical sensors.

The Analyst 20060901

Alpha-lipoic acid. Monograph.

Alternative medicine review : a journal of clinical therapeutic 20060901

Effects of antioxidant supplementation and exercise training on erythrocyte antioxidant enzymes.

International journal for vitamin and nutrition research. Internationale Zeitschrift fur Vitamin- und Ernahrungsforschung. Journal international de vitaminologie et de nutrition 20060901

Beneficial effect of low ethanol intake on the cardiovascular system: possible biochemical mechanisms.

Vascular health and risk management 20060901

Orthomolecular medicine: the therapeutic use of dietary supplements for anti-aging.

Clinical interventions in aging 20060901

A comparative study of capacitive immunosensors based on self-assembled monolayers formed from thiourea, thioctic acid, and 3-mercaptopropionic acid.

Biosensors & bioelectronics 20060815

Chronic systemic D-galactose exposure induces memory loss, neurodegeneration, and oxidative damage in mice: protective effects of R-alpha-lipoic acid.

Journal of neuroscience research 20060815

Lipoic acid affects cellular migration into the central nervous system and stabilizes blood-brain barrier integrity.

Journal of immunology (Baltimore, Md. : 1950) 20060815

Protective effect of DL-alpha-lipoic acid on cyclophosphamide induced hyperlipidemic cardiomyopathy.

European journal of pharmacology 20060814

Lipoyl synthase inserts sulfur atoms into an octanoyl substrate in a stepwise manner.

Angewandte Chemie (International ed. in English) 20060804

Modifications of the lipoamide-containing mitochondrial subproteome in a yeast mutant defective in cysteine desulfurase.

Molecular & cellular proteomics : MCP 20060801

RS-alpha-lipoic acid protects cholinergic cells against sodium nitroprusside and amyloid-beta neurotoxicity through restoration of acetyl-CoA level.

Journal of neurochemistry 20060801

alpha-Lipoic acid prevents the increase in atherosclerosis induced by diabetes in apolipoprotein E-deficient mice fed high-fat/low-cholesterol diet.

Diabetes 20060801

Structural and biochemical characterization of a mitochondrial peroxiredoxin from Plasmodium falciparum.

Molecular microbiology 20060801

Whitening effect of a dermocosmetic formulation: a randomized double-blind controlled study on melasma.

International journal of cosmetic science 20060801

Antioxidants reduce cone cell death in a model of retinitis pigmentosa.

Proceedings of the National Academy of Sciences of the United States of America 20060725

Identification and solution structures of a single domain biotin/lipoyl attachment protein from Bacillus subtilis.

The Journal of biological chemistry 20060721

Modification of cyclophosphamide-induced clastogenesis and apoptosis in rats by alpha-lipoic acid.

Mutation research 20060714

Design and synthesis of the first generation of dithiolane thiazolidinedione- and phenylacetic acid-based PPARgamma agonists.

Journal of medicinal chemistry 20060713

Toxoplasma gondii scavenges host-derived lipoic acid despite its de novo synthesis in the apicoplast.

The EMBO journal 20060712

Oxidative renal injury and lipoprotein oxidation in hypercholesterolemic atherogenesis: Role of eicosapentaenoate-lipoate (EPA-LA) derivative.

Prostaglandins, leukotrienes, and essential fatty acids 20060701

alpha-lipoic acid regulates AMP-activated protein kinase and inhibits insulin secretion from beta cells.

Diabetologia 20060701

Expanding role of AMPK in endocrinology.

Trends in endocrinology and metabolism: TEM 20060701

Managing psychiatric disorders with antidiabetic agents: translational research and treatment opportunities.

Expert opinion on pharmacotherapy 20060701

Effect of dietary lipoic acid on metabolic hormones and acute-phase proteins during challenge with infectious bovine rhinotracheitis virus in cattle.

American journal of veterinary research 20060701

Contact dermatitis to alpha-lipoic acid in an anti-wrinkle cream.

Contact dermatitis 20060701

L-carnitine and alpha-lipoic acid improve age-associated decline in mitochondrial respiratory chain activity of rat heart muscle.

The journals of gerontology. Series A, Biological sciences and medical sciences 20060701

Cellular disulfide-reducing capacity: an integrated measure of cell redox capacity.

Biochemical and biophysical research communications 20060616

Lipoic acid downmodulates CD4 from human T lymphocytes by dissociation of p56(Lck).

Biochemical and biophysical research communications 20060609

Oxidative stress-mediated macromolecular damage and dwindle in antioxidant status in aged rat brain regions: role of L-carnitine and DL-alpha-lipoic acid.

Clinica chimica acta; international journal of clinical chemistry 20060601

Chronic systemic D-galactose exposure induces memory loss, neurodegeneration, and oxidative damage in mice: protective effects of R-alpha-lipoic acid.

Journal of neuroscience research 20060601

Lipoic acid inhibits expression of ICAM-1 and VCAM-1 by CNS endothelial cells and T cell migration into the spinal cord in experimental autoimmune encephalomyelitis.

Journal of neuroimmunology 20060601

Pre-operative preparation for cardiac surgery utilising a combination of metabolic, physical and mental therapy.

Heart, lung & circulation 20060601

Effects of dietary lipoic acid on plasma lipid, in vivo insulin sensitivity, metabolic response to corticosterone and in vitro lipolysis in broiler chickens.

The British journal of nutrition 20060601

New and emerging treatment options for neuropathic pain.

The American journal of managed care 20060601

Lead toxicity part II: the role of free radical damage and the use of antioxidants in the pathology and treatment of lead toxicity.

Alternative medicine review : a journal of clinical therapeutic 20060601

[Estimation of the effect of lipoic acid in the rat's lung during lipopolysaccharide-induced oxidative stress].

Polski merkuriusz lekarski : organ Polskiego Towarzystwa Lekarskiego 20060601

Preparation and characterization of polypeptide-stabilized gold nanoparticles.

Journal of nanoscience and nanotechnology 20060601

Alpha-lipoic acid prevents lipotoxic cardiomyopathy in acyl CoA-synthase transgenic mice.

Biochemical and biophysical research communications 20060526

Salubrious effects of lipoic acid against adriamycin-induced clastogenesis and apoptosis in Wistar rat bone marrow cells.

Toxicology 20060515

Expression of the kidney injury molecule 1 in the rat cochlea and induction by cisplatin.

Neuroscience 20060512

Fluorinated amphiphilic amino acid derivatives as antioxidant carriers: a new class of protective agents.

Journal of medicinal chemistry 20060504

Protective effect of lipoic acid on cyclophosphamide-induced testicular toxicity.

Clinica chimica acta; international journal of clinical chemistry 20060501

Effect of R-(+)-alpha-lipoic acid on experimental diabetic retinopathy.

Diabetologia 20060501

Nordihydroguaiaretic acid is a potent in vitro scavenger of peroxynitrite, singlet oxygen, hydroxyl radical, superoxide anion and hypochlorous acid and prevents in vivo ozone-induced tyrosine nitration in lungs.

Free radical research 20060501

Lipoic acid supplementation prevents cyclosporine-induced hypertension and nephrotoxicity in spontaneously hypertensive rats.

Journal of hypertension 20060501

Antioxidant alpha-lipoic acid inhibits osteoclast differentiation by reducing nuclear factor-kappaB DNA binding and prevents in vivo bone resorption induced by receptor activator of nuclear factor-kappaB ligand and tumor necrosis factor-alpha.

Free radical biology & medicine 20060501

HIV-1 integrase inhibition of biscoumarin analogues.

Chemical & pharmaceutical bulletin 20060501

A phase II study with antioxidants, both in the diet and supplemented, pharmaconutritional support, progestagen, and anti-cyclooxygenase-2 showing efficacy and safety in patients with cancer-related anorexia/cachexia and oxidative stress.

Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 20060501

Evidence for covalent lipoyl adduction with dopaquinone following tyrosinase-catalyzed oxidation.

Biochemical and biophysical research communications 20060428

[Recent changes in concepts of antioxidant treatment].

Orvosi hetilap 20060423

Alpha-tocopherol (vitamin E) induces rapid, nonsustained proliferation in cultured rat microglia.

Glia 20060415

Heme oxygenase-1 contributes to the cytoprotection of alpha-lipoic acid via activation of p44/42 mitogen-activated protein kinase in vascular smooth muscle cells.

Free radical biology & medicine 20060415

Biotin uptake and cellular translocation in human derived retinoblastoma cell line (Y-79): a role of hSMVT system.

International journal of pharmaceutics 20060407

[The role of antioxidants in prevention].

Orvosi hetilap 20060402

Effect of lipid peroxides and antioxidants on glycation of hemoglobin: an in vitro study on human erythrocytes.

Clinica chimica acta; international journal of clinical chemistry 20060401

Mitochondrial membrane damage during aging process in rat heart: potential efficacy of L-carnitine and DL alpha lipoic acid.

Mechanisms of ageing and development 20060401

Protection against radiation-induced oxidative stress in cultured human epithelial cells by treatment with antioxidant agents.

International journal of radiation oncology, biology, physics 20060401

The activity of a thermostable lipoyl synthase from Sulfolobus solfataricus with a synthetic octanoyl substrate.

Analytical biochemistry 20060401

Effects of dietary supplements on the space radiation-induced reduction in total antioxidant status in CBA mice.

Radiation research 20060401

Modulation of cardiac and aortic peroxisome proliferator-activated receptor-gamma expression by oxidative stress in chronically glucose-fed rats.

American journal of hypertension 20060401

Vitamin E and alpha-lipoic acid supplementation increase bleeding tendency via an intrinsic coagulation pathway.

Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis 20060401

Carnitine and lipoic acid alleviates protein oxidation in heart mitochondria during aging process.

Biogerontology 20060401

Oxidative stress and DNA single strand breaks in skeletal muscle of aged rats: role of carnitine and lipoicacid.

Biogerontology 20060401

Modulatory role of lipoic acid on adriamycin-induced testicular injury.

Chemico-biological interactions 20060325

Co-repressor induced order and biotin repressor dimerization: a case for divergent followed by convergent evolution.

Journal of molecular biology 20060324

Alpha-lipoic acid exhibits anti-amyloidogenicity for beta-amyloid fibrils in vitro.

Biochemical and biophysical research communications 20060324

Free radicals, metals and antioxidants in oxidative stress-induced cancer.

Chemico-biological interactions 20060310

An NMDA receptor-dependent hydroxyl radical pathway in the rabbit hypothalamus may mediate lipopolysaccharide fever.

Neuropharmacology 20060301

The long-term survival of a patient with pancreatic cancer with metastases to the liver after treatment with the intravenous alpha-lipoic acid/low-dose naltrexone protocol.

Integrative cancer therapies 20060301

Size series of small indium arsenide-zinc selenide core-shell nanocrystals and their application to in vivo imaging.

Journal of the American Chemical Society 20060301

MafA expression and insulin promoter activity are induced by nicotinamide and related compounds in INS-1 pancreatic beta-cells.

Diabetes 20060301

Supply of R-alpha-lipoic acid and glutamine to casein-fed mice influences the number of B lymphocytes and tissue glutathione levels during endotoxemia.

Wiener klinische Wochenschrift 20060301

Structure of a putative lipoate protein ligase from Thermoplasma acidophilum and the mechanism of target selection for post-translational modification.

Journal of molecular biology 20060224

L-dopa- and dopamine-(R)-alpha-lipoic acid conjugates as multifunctional codrugs with antioxidant properties.

Journal of medicinal chemistry 20060223

Protective effect of lipoic acid on micronuclei induction by cyclophosphamide.

Archives of toxicology 20060201

Synthesis and effects of 3-methylthiopropanoyl thiolesters of lipoic acid, methional metabolite mimics.

Bioorganic chemistry 20060201

Diabetic neuropathy.

Postgraduate medical journal 20060201

A versatile conformational switch regulates reactivity in human branched-chain alpha-ketoacid dehydrogenase.

Structure (London, England : 1993) 20060201

GLUT4 repression in response to oxidative stress is associated with reciprocal alterations in C/EBP alpha and delta isoforms in 3T3-L1 adipocytes.

Archives of physiology and biochemistry 20060201

Chemoprotective effect of lipoic acid against cyclophosphamide-induced changes in the rat sperm.

Toxicology 20060105

Effect of alpha-lipoic acid supplementation on markers of protein oxidation in post-mitotic tissues of ageing rat.

Cell biochemistry and function 20060101

Lipoic acid modulates adriamycin-induced testicular toxicity.

Reproductive toxicology (Elmsford, N.Y.) 20060101

Nutritional therapy improves function and complements corticosteroid intervention in mdx mice.

Muscle & nerve 20060101

Pro-oxidant actions of alpha-lipoic acid and dihydrolipoic acid.

Medical hypotheses 20060101

Preservation of pressure-induced cutaneous vasodilation by limiting oxidative stress in short-term diabetic mice.

Cardiovascular research 20060101

alpha-Lipoic acid and N-acetyl cysteine prevent zinc deficiency-induced activation of NF-kappaB and AP-1 transcription factors in human neuroblastoma IMR-32 cells.

Free radical research 20060101

Induction of heat shock proteins may combat insulin resistance.

Medical hypotheses 20060101

Exercise training and the antioxidant alpha-lipoic acid in the treatment of insulin resistance and type 2 diabetes.

Free radical biology & medicine 20060101

alpha-Lipoic acid inhibits inflammatory bone resorption by suppressing prostaglandin E2 synthesis.

Journal of immunology (Baltimore, Md. : 1950) 20060101

Preincubation of rat and human hepatocytes with cytoprotectants prior to cryopreservation can improve viability and function upon thawing.

Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society 20060101

Decrease in NADPH-cytochrome P450 reductase activity of the human heart, Liver and lungs in the presence of alpha-lipoic acid.

Annals of nutrition & metabolism 20060101

Supplemental conditionally essential nutrients in cardiovascular disease therapy.

The Journal of cardiovascular nursing 20060101

Antioxidant supplementation enhances erythrocyte antioxidant status and attenuates cyclosporine-induced vascular dysfunction.

American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20060101

Alpha-tocopherol and alpha-lipoic acid enhance the erythrocyte antioxidant defence in cyclosporine A-treated rats.

Basic & clinical pharmacology & toxicology 20060101

Menopause: a review on the role of oxygen stress and favorable effects of dietary antioxidants.

Archives of gerontology and geriatrics 20060101

D-MEKK1, the Drosophila orthologue of mammalian MEKK4/MTK1, and Hemipterous/D-MKK7 mediate the activation of D-JNK by cadmium and arsenite in Schneider cells.

BMC cell biology 20060101

Synthesis, characterization and biological activity of chemically modified insulin derivative with alpha lipoic acid.

Protein and peptide letters 20060101

Diabetes--a man made disease.

Medical hypotheses 20060101

Reduction in podocyte density as a pathologic feature in early diabetic nephropathy in rodents: prevention by lipoic acid treatment.

BMC nephrology 20060101

Increased proinflammatory endothelial response to S100A8/A9 after preactivation through advanced glycation end products.

Cardiovascular diabetology 20060101

Synthesis and grafting of thioctic acid-PEG-folate conjugates onto Au nanoparticles for selective targeting of folate receptor-positive tumor cells.

Bioconjugate chemistry 20060101

Protective efficacy of alpha-lipoic acid on acetylcholinesterase activity in aged rat brain regions.

Rejuvenation research 20060101

Functional characterization of sodium-dependent multivitamin transporter in MDCK-MDR1 cells and its utilization as a target for drug delivery.

Molecular pharmaceutics 20060101

Free radical theory of autoimmunity.

Theoretical biology & medical modelling 20060101

An overdose of alpha lipoic acid may cause trace element deficiency in diabetes mellitus.

Medical hypotheses 20060101

Oxidative stress and antioxidant defense in patients with chronic hepatitis C patients before and after pegylated interferon alfa-2b plus ribavirin therapy.

Journal of translational medicine 20060101

Heat shock protein 60 response to exercise in diabetes: effects of alpha-lipoic acid supplementation.

Journal of diabetes and its complications 20060101

A zebrafish assay for identifying neuroprotectants in vivo.

Neurotoxicology and teratology 20060101

Adjuvant strategies for prevention of glomerulosclerosis.

Medical hypotheses 20060101

Mutagenic and carcinogenic potential of menadione.

Neoplasma 20060101

Protective effects of early administration of alpha-lipoic acid against lipopolysaccharide-induced plasma lipid peroxidation.

Pharmacological reports : PR 20060101

Ethanol-dependent toxicity in zebrafish is partially attenuated by antioxidants.

Neurotoxicology and teratology 20060101

The role of thiols in liver ischemia-reperfusion injury.

Current pharmaceutical design 20060101

[Neurometabolic therapy of diabetic neuropathy].

Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova 20060101

[Pharmacological correction of energy metabolism disturbance in the inflammatory-dystrophic process in the periodontium].

Eksperimental'naia i klinicheskaia farmakologiia 20060101

Activity of the dietary antioxidant ergothioneine in a virus gene-based assay for inhibitors of HIV transcription.

BioFactors (Oxford, England) 20060101

Different protection mechanisms after pretreatment with glycine or alpha-lipoic acid in a rat model of warm hepatic ischemia.

European surgical research. Europaische chirurgische Forschung. Recherches chirurgicales europeennes 20060101

Alterations of metabolic activity in human osteoarthritic osteoblasts by lipid peroxidation end product 4-hydroxynonenal.

Arthritis research & therapy 20060101

Effect of antioxidant capacity on blood lipid metabolism and lipoprotein lipase activity of rats fed a high-fat diet.

Nutrition (Burbank, Los Angeles County, Calif.) 20060101

Clinical applications of lipoic acid in type II diabetes mellitus.

Holistic nursing practice 20060101

Improvement of insulin sensitivity in patients with type 2 diabetes mellitus after oral administration of alpha-lipoic acid.

Hormones (Athens, Greece) 20060101

[Efficacy of magnetotherapy in diabetic peripheral neuropathy in children].

Voprosy kurortologii, fizioterapii, i lechebnoi fizicheskoi kultury 20060101

Stimulation of membrane permeability transition by alpha-lipoic acid and its biochemical characteristics.

Physiological chemistry and physics and medical NMR 20060101

Combined efficacies of DL-alpha-lipoic acid and meso 2,3 dimercaptosuccinic acid against arsenic induced toxicity in antioxidant systems of rats.

Toxicology letters 20051230

The reaction of LipB, the octanoyl-[acyl carrier protein]:protein N-octanoyltransferase of lipoic acid synthesis, proceeds through an acyl-enzyme intermediate.

Biochemistry 20051220

The AFM measured force required to rupture the dithiolate linkage of thioctic acid to gold is less than the rupture force of a simple gold-alkyl thiolate bond.

Langmuir : the ACS journal of surfaces and colloids 20051220

The photochemistry of lipoic acid: photoionization and observation of a triplet excited state of a disulfide.

Chemphyschem : a European journal of chemical physics and physical chemistry 20051209

Tethered bilayer lipid membranes based on monolayers of thiolipids mixed with a complementary dilution molecule. 1. Incorporation of channel peptides.

Langmuir : the ACS journal of surfaces and colloids 20051206

Alpha-lipoic acid prevents endothelial dysfunction in obese rats via activation of AMP-activated protein kinase.

Arteriosclerosis, thrombosis, and vascular biology 20051201

Antioxidant nutrient intake and supplements as potential moderators of cognitive decline and cardiovascular disease in obstructive sleep apnea.

Sleep medicine reviews 20051201

Lipoic acid decreases exhaled nitric oxide concentrations in anesthetized endotoxemic rats.

Vascular pharmacology 20051201

Attenuation of oxidative stress in HL-1 cardiomyocytes improves mitochondrial function and stabilizes Hif-1alpha.

Free radical research 20051201

Age-associated deficit of mitochondrial oxidative phosphorylation in skeletal muscle: role of carnitine and lipoic acid.

Molecular and cellular biochemistry 20051201

Preincubation of rat and human hepatocytes with cytoprotectants prior to cryopreservation can improve viability and function upon thawing.

Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society 20051201

Neurodegeneration from mitochondrial insufficiency: nutrients, stem cells, growth factors, and prospects for brain rebuilding using integrative management.

Alternative medicine review : a journal of clinical therapeutic 20051201

Thioredoxin and lipoic acid catalyze the denitrosation of low molecular weight and protein S-nitrosothiols.

Journal of the American Chemical Society 20051116

Crystal structure of lipoate-protein ligase A bound with the activated intermediate: insights into interaction with lipoyl domains.

The Journal of biological chemistry 20051111

dl-alpha-lipoic acid ameliorates cyclophosphamide induced cardiac mitochondrial injury.

Toxicology 20051105

Obesity: the role of hypothalamic AMP-activated protein kinase in body weight regulation.

The international journal of biochemistry & cell biology 20051101

A prodrug of cysteine, L-2-oxothiazolidine-4-carboxylic acid, regulates vascular permeability by reducing vascular endothelial growth factor expression in asthma.

Molecular pharmacology 20051101

Thioredoxin and dihydrolipoic acid inhibit elastase activity in cystic fibrosis sputum.

American journal of physiology. Lung cellular and molecular physiology 20051101

Effect of dietary alpha-lipoic acid on growth, body composition, muscle pH, and AMP-activated protein kinase phosphorylation in mice.

Journal of animal science 20051101

Protective effects of different antioxidants and amrinone on vancomycin-induced nephrotoxicity.

Basic & clinical pharmacology & toxicology 20051101

Plasmodium falciparum possesses organelle-specific alpha-keto acid dehydrogenase complexes and lipoylation pathways.

Biochemical Society transactions 20051101

(R)-alpha-lipoic acid protects retinal pigment epithelial cells from oxidative damage.

Investigative ophthalmology & visual science 20051101

Glutathione turnover in human cell lines in the presence of agents with glutathione influencing potential with and without acivicin inhibition of gamma-glutamyltranspeptidase.

Biochimica et biophysica acta 20051030

Protective effect of alpha-lipoic acid in lipopolysaccharide-induced endothelial fractalkine expression.

Circulation research 20051028

Characterization of the redox components of transplasma membrane electron transport system from Leishmania donovani promastigotes.

Biochimica et biophysica acta 20051010

Efficacy of levo carnitine and alpha lipoic acid in ameliorating the decline in mitochondrial enzymes during aging.

Clinical nutrition (Edinburgh, Scotland) 20051001

Protective effect of lipoic acid on adriamycin-induced testicular toxicity.

Clinica chimica acta; international journal of clinical chemistry 20051001

Alpha-lipoic acid-induced heme oxygenase-1 expression is mediated by nuclear factor erythroid 2-related factor 2 and p38 mitogen-activated protein kinase in human monocytic cells.

Arteriosclerosis, thrombosis, and vascular biology 20051001

Efficient production of reactive oxygen species in neural precursor cells after exposure to 250 MeV protons.

Radiation research 20051001

Lipoic acid improves glucose utilisation and prevents protein glycation and AGE formation.

Die Pharmazie 20051001

Exercise and mononuclear cell DNA damage: the effects of antioxidant supplementation.

International journal of sport nutrition and exercise metabolism 20051001

Effects of dietary α-lipoic acid on glycolysis of postmortem muscle.

Meat science 20051001

Oxidative stress--mediated alterations in glucose dynamics in a genetic animal model of type II diabetes.

Life sciences 20050930

Crystal structure of lipoate-protein ligase A from Escherichia coli. Determination of the lipoic acid-binding site.

The Journal of biological chemistry 20050930

Quantification of lipoic acid in plasma by high-performance liquid chromatography-electrospray ionization mass spectrometry.

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20050925

Self-assembly and multistage redox chemistry of strong electron acceptors on metal surfaces: polynitrofluorenes on gold and platinum.

Langmuir : the ACS journal of surfaces and colloids 20050913

Crystal structure of human T-protein of glycine cleavage system at 2.0 A resolution and its implication for understanding non-ketotic hyperglycinemia.

Journal of molecular biology 20050902

Treatment of chronic hepatitis C virus infection via antioxidants: results of a phase I clinical trial.

Journal of clinical gastroenterology 20050901

Effects of triple antioxidant combination (vitamin E, vitamin C and alpha-lipoic acid) with insulin on lipid and cholesterol levels and fatty acid composition of brain tissue in experimental diabetic and non-diabetic rats.

Cell biology international 20050901

Endogenous production of lipoic acid is essential for mouse development.

Molecular and cellular biology 20050901

A novel approach based on lipid nanoparticles (SLN) for topical delivery of alpha-lipoic acid.

Journal of microencapsulation 20050901

Stimuli-sensitive thin films prepared by a layer-by-layer deposition of 2-iminobiotin-labeled poly(ethyleneimine) and avidin.

Langmuir : the ACS journal of surfaces and colloids 20050830

Alpha-lipoic acid protects against cholecystokinin-induced acute pancreatitis in rats.

World journal of gastroenterology 20050821

Effect of antioxidant-enriched diets on glutathione redox status in tissue homogenates and mitochondria of the senescence-accelerated mouse.

Free radical biology & medicine 20050815

Lipid peroxides and antioxidant enzymes in cisplatin-induced chronic nephrotoxicity in rats.

Mediators of inflammation 20050814

Effects of alpha-lipoic acid on kinin B1 and B2 receptor binding sites in the spinal cord of chronically angiotensin-treated rats.

Peptides 20050801

Differential impact of environmental stresses on the pea mitochondrial proteome.

Molecular & cellular proteomics : MCP 20050801

N-acetylcysteine decreases angiotensin II receptor binding in vascular smooth muscle cells.

Journal of the American Society of Nephrology : JASN 20050801

Pretreatment of diabetic rats with lipoic acid improves healing of subsequently-induced abrasion wounds.

Archives of dermatological research 20050801

Insulin, AGE and hypertension.

Journal of hypertension 20050801

Increases of spinal kinin receptor binding sites in two rat models of insulin resistance.

Peptides 20050801

Iron-binding drugs targeted to lysosomes: a potential strategy to treat inflammatory lung disorders.

Expert opinion on investigational drugs 20050801

A cooperative effect of bifunctionalized nanoparticles on recognition: sensing alkali ions by crown and carboxylate moieties in aqueous media.

Analytical chemistry 20050801

Cytoprotective role of DL-alpha-lipoic acid in cyclophosphamide induced myocardial toxicity.

Molecular and cellular biochemistry 20050801

Effects of metabolic modifiers such as carnitines, coenzyme Q10, and PUFAs against different forms of neurotoxic insults: metabolic inhibitors, MPTP, and methamphetamine.

Annals of the New York Academy of Sciences 20050801

alpha-Lipoic acid supplementation inhibits oxidative damage, accelerating chronic wound healing in patients undergoing hyperbaric oxygen therapy.

Biochemical and biophysical research communications 20050729

Crystal structure of human dihydrolipoamide dehydrogenase: NAD+/NADH binding and the structural basis of disease-causing mutations.

Journal of molecular biology 20050715

Peroxynitrite-derived carbonate and nitrogen dioxide radicals readily react with lipoic and dihydrolipoic acid.

Free radical biology & medicine 20050715

Thioctic acid amides: convenient tethers for achieving low nonspecific protein binding to carbohydrates presented on gold surfaces.

Chemical communications (Cambridge, England) 20050714

Alpha-lipoic acid increases insulin sensitivity by activating AMPK in skeletal muscle.

Biochemical and biophysical research communications 20050708

Role of hypothalamic 5'-AMP-activated protein kinase in the regulation of food intake and energy homeostasis.

Journal of molecular medicine (Berlin, Germany) 20050701

Ascochlorin inhibits matrix metalloproteinase-9 expression by suppressing activator protein-1-mediated gene expression through the ERK1/2 signaling pathway: inhibitory effects of ascochlorin on the invasion of renal carcinoma cells.

The Journal of biological chemistry 20050701

Alpha-lipoic acid inhibits TNF-alpha-induced apoptosis in human bone marrow stromal cells.

Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 20050701

Dietary lipoic acid supplementation attenuates hypertension in Dahl salt sensitive rats.

Molecular and cellular biochemistry 20050701

Substantial inhibition of chromate induced DNA-protein crosslink formation in vivo by α-lipoic acid.

Environmental toxicology and pharmacology 20050701

The effects of aging and oxidative stress on learning behavior in C. elegans.

Neurobiology of aging 20050601

Elimination of high amounts of extracellular homocysteine in human cell lines.

Clinica chimica acta; international journal of clinical chemistry 20050601

Treatment for diabetic mononeuropathy with alpha-lipoic acid.

International journal of clinical practice 20050601

Alpha-lipoic acid suppresses osteoclastogenesis despite increasing the receptor activator of nuclear factor kappaB ligand/osteoprotegerin ratio in human bone marrow stromal cells.

The Journal of endocrinology 20050601

Effects of supplementation with alpha-lipoic acid on exercise-induced activation of coagulation.

Metabolism: clinical and experimental 20050601

Prevention of chromate induced oxidative stress by alpha-lipoic acid.

Indian journal of experimental biology 20050601

[Pathogenesis and progression of neuropathies in diabetic patients with endothelial dysfunction].

Nihon rinsho. Japanese journal of clinical medicine 20050601

Molecular targets of diabetic vascular complications and potential new drugs.

Current drug targets 20050601

Partial protection by lipoic acid against carboplantin-induced ototoxicity in rats.

Biomedical and environmental sciences : BES 20050601

Brain regional responses in antioxidant system to alpha-lipoic acid in arsenic intoxicated rat.

Toxicology 20050515

Arsenic trioxide (As(2)O(3)) induces apoptosis through activation of Bax in hematopoietic cells.

Oncogene 20050505

Lipoic acid prevents collagen abnormalities in tail tendon of high-fructose-fed rats.

Diabetes, obesity & metabolism 20050501

Gene expression profiling studies of aging in cardiac and skeletal muscles.

Cardiovascular research 20050501

Oxidative stress on mitochondrial antioxidant defense system in the aging process: role of DL-alpha-lipoic acid and L-carnitine.

Clinica chimica acta; international journal of clinical chemistry 20050501

Attenuation of serum lipid abnormalities and cardiac oxidative stress by eicosapentaenoate-lipoate (EPA-LA) derivative in experimental hypercholesterolemia.

Clinica chimica acta; international journal of clinical chemistry 20050501

Chemical xenobiotics and mitochondrial autoantigens in primary biliary cirrhosis: identification of antibodies against a common environmental, cosmetic, and food additive, 2-octynoic acid.

Journal of immunology (Baltimore, Md. : 1950) 20050501

Phylogenetic and immunological definition of four lipoylated proteins from Novosphingobium aromaticivorans, implications for primary biliary cirrhosis.

Journal of autoimmunity 20050501

Motexafin gadolinium disrupts zinc metabolism in human cancer cell lines.

Cancer research 20050501

Evidence for a non-antioxidant, dose-dependent role of alpha -lipoic acid in caspase-3 and ERK2 activation in endothelial cells.

Apoptosis : an international journal on programmed cell death 20050501

The protective role of DL-alpha-lipoic acid in biogenic amines catabolism triggered by Abeta amyloid vaccination in mice.

Brain research bulletin 20050430

Pyruvate protects motor neurons expressing mutant superoxide dismutase 1 against copper toxicity.

Neuroreport 20050425

Structure of P-protein of the glycine cleavage system: implications for nonketotic hyperglycinemia.

The EMBO journal 20050420

Functionalization of thioctic acid-capped gold nanoparticles for specific immobilization of histidine-tagged proteins.

Journal of the American Chemical Society 20050420

Thermodynamics of the As(III)-thiol interaction: arsenite and monomethylarsenite complexes with glutathione, dihydrolipoic acid, and other thiol ligands.

Inorganic chemistry 20050418

Biotin uptake by human proximal tubular epithelial cells: cellular and molecular aspects.

American journal of physiology. Renal physiology 20050401

Cloning, expression, and characterization of the human mitochondrial beta-ketoacyl synthase. Complementation of the yeast CEM1 knock-out strain.

The Journal of biological chemistry 20050401

Short-term hyperglycemia produces oxidative damage and apoptosis in neurons.

FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20050401

Determination of ultrafast protein folding rates from loop formation dynamics.

Journal of molecular biology 20050401

The Wolbachia genome of Brugia malayi: endosymbiont evolution within a human pathogenic nematode.

PLoS biology 20050401

Mechanisms of antioxidant and pro-oxidant effects of alpha-lipoic acid in the diabetic and nondiabetic kidney.

Kidney international 20050401

Lipoic acid in multiple sclerosis: a pilot study.

Multiple sclerosis (Houndmills, Basingstoke, England) 20050401

Clinical management of oxaliplatin-associated neurotoxicity.

Clinical colorectal cancer 20050401

Mitigation of oxidative stress in cyclophosphamide-challenged hepatic tissue by DL-alpha-lipoic acid.

Molecular and cellular biochemistry 20050401

Immobilization of single-stranded DNA by self-assembled polymer on gold substrate for a DNA chip.

Biotechnology and bioengineering 20050330

Synthesis of compact multidentate ligands to prepare stable hydrophilic quantum dot fluorophores.

Journal of the American Chemical Society 20050323

Synthesis, characterization of dihydrolipoic acid capped gold nanoparticles, and functionalization by the electroluminescent luminol.

Langmuir : the ACS journal of surfaces and colloids 20050315

Mechanistic investigations of lipoic acid biosynthesis in Escherichia coli: both sulfur atoms in lipoic acid are contributed by the same lipoyl synthase polypeptide.

Journal of the American Chemical Society 20050309

Pharmacokinetics of alpha-lipoic acid in subjects with severe kidney damage and end-stage renal disease.

Journal of clinical pharmacology 20050301

Effects of glucose and insulin on the development of oxidative stress and hypertension in animal models of type 1 and type 2 diabetes.

Journal of hypertension 20050301

Bcl-2 in endothelial cells is increased by vitamin E and alpha-lipoic acid supplementation but not exercise training.

Journal of molecular and cellular cardiology 20050301

Pesticide spraying and health effects.

Environmental health perspectives 20050301

Syntheses of novel indole lipoic acid derivatives and their antioxidant effects on lipid peroxidation.

Archiv der Pharmazie 20050301

Arsenic intoxication-induced reduction of glutathione level and of the activity of related enzymes in rat brain regions: reversal by DL-alpha-lipoic acid.

Archives of toxicology 20050301

alpha-Lipoic acid induces apoptosis in human colon cancer cells by increasing mitochondrial respiration with a concomitant O2-*-generation.

Apoptosis : an international journal on programmed cell death 20050301

Inhibition of gelatinase B (matrix metalloproteinase-9) by dihydrolipoic acid.

Canadian journal of physiology and pharmacology 20050301

Effect of ethanol on the response of the rat urinary bladder to in vitro ischemia: protective effect of alpha-lipoic acid.

Molecular and cellular biochemistry 20050301

Oriented assembly of Au nanorods using biorecognition system.

Chemical communications (Cambridge, England) 20050227

Beneficial effects of DL-alpha-lipoic acid on cyclophosphamide-induced oxidative stress in mitochondrial fractions of rat testis.

Chemico-biological interactions 20050227

A pulsed potential waveform displaying enhanced detection capabilities towards sulfur-containing compounds at a gold working electrode.

Journal of chromatography. A 20050225

Effects of antioxidant treatment on normal and diabetic rat retinal enzyme activities.

Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics 20050201

Effects of dietary antioxidant supplementation before and after oral acetaminophen challenge in cats.

American journal of veterinary research 20050201

The protective role of DL-alpha-lipoic acid in the oxidative vulnerability triggered by Abeta-amyloid vaccination in mice.

Molecular and cellular biochemistry 20050201

Rational approach to discover multipotent anti-Alzheimer drugs.

Journal of medicinal chemistry 20050127

Irbesartan and lipoic acid improve endothelial function and reduce markers of inflammation in the metabolic syndrome: results of the Irbesartan and Lipoic Acid in Endothelial Dysfunction (ISLAND) study.

Circulation 20050125

Interventions for the treatment of burning mouth syndrome.

The Cochrane database of systematic reviews 20050125

Expression cloning and demonstration of Enterococcus faecalis lipoamidase (pyruvate dehydrogenase inactivase) as a Ser-Ser-Lys triad amidohydrolase.

The Journal of biological chemistry 20050121

Protein oxidative damage in arsenic induced rat brain: influence of DL-alpha-lipoic acid.

Toxicology letters 20050115

Effect of advanced glycation end products on accelerated apoptosis of retinal capillary cells under in vitro conditions.

Life sciences 20050114

Design, synthesis, and biological evaluation of prazosin-related derivatives as multipotent compounds.

Journal of medicinal chemistry 20050113

alpha-Lipoic acid prevents diabetes mellitus in diabetes-prone obese rats.

Biochemical and biophysical research communications 20050107

Prevention of doxorubicin-induced acute cardiotoxicity by an experimental antioxidant compound.

Journal of cardiovascular pharmacology 20050101

Can cognitive deterioration associated with Down syndrome be reduced?

Medical hypotheses 20050101

Proteomic analysis of specific brain proteins in aged SAMP8 mice treated with alpha-lipoic acid: implications for aging and age-related neurodegenerative disorders.

Neurochemistry international 20050101

The protective effect of alpha-lipoic acid against oxidative damage in rabbit conjunctiva and cornea exposed to ultraviolet radiation.

Ophthalmologica. Journal international d'ophtalmologie. International journal of ophthalmology. Zeitschrift fur Augenheilkunde 20050101

Disintegration of layer-by-layer assemblies composed of 2-iminobiotin-labeled poly(ethyleneimine) and avidin.

Biomacromolecules 20050101

The carbonyl scavengers aminoguanidine and tenilsetam protect against the neurotoxic effects of methylglyoxal.

Neurotoxicity research 20050101

The responses of Ht22 cells to oxidative stress induced by buthionine sulfoximine (BSO).

BMC neuroscience 20050101

Integrated treatment approach improves cognitive function in demented and clinically depressed patients.

American journal of Alzheimer's disease and other dementias 20050101

[Functional state of the liver in patients with an acute destructive pancreatitis in the early postoperative period].

Klinichna khirurhiia 20050101

Effects of antioxidants coenzyme Q10 and lipoic acid on interleukin-1 beta-mediated inhibition of glucose-stimulated insulin release from cultured mouse pancreatic islets.

Immunopharmacology and immunotoxicology 20050101

Lipoic acid ameliorates adriamycin-induced testicular mitochondriopathy.

Reproductive toxicology (Elmsford, N.Y.) 20050101

Prooxidant activities of alpha-lipoic acid on oxidative protein damage in the aging rat heart muscle.

Archives of gerontology and geriatrics 20050101

Dietary supplementation with (R)-alpha-lipoic acid reverses the age-related accumulation of iron and depletion of antioxidants in the rat cerebral cortex.

Redox report : communications in free radical research 20050101

[Treatment of Chagas disease with benznidazole and thioctic acid].

Medicina 20050101

Oxidative stress and the use of antioxidants in diabetes: linking basic science to clinical practice.

Cardiovascular diabetology 20050101

Complementary therapies for diabetes: the case for chromium, magnesium, and antioxidants.

Archives of medical research 20050101

[Regional anesthesia and timely treatment for neuropathy in patients with pyonecrotic forms of the diabetic foot].

Anesteziologiia i reanimatologiia 20050101

A randomized, double-blind, placebo-controlled study on the clinical efficacy of oral treatment with DermaVite on ageing symptoms of the skin.

The Journal of international medical research 20050101

The plasmodial apicoplast was retained under evolutionary selective pressure to assuage blood stage oxidative stress.

Medical hypotheses 20050101

Utilization of the insulin-signaling network in the metabolic actions of alpha-lipoic acid-reduction or oxidation?

Antioxidants & redox signaling 20050101

The molecular basis for oxidative stress-induced insulin resistance.

Antioxidants & redox signaling 20050101

Plasma protein oxidation in aging rats after alpha-lipoic acid administration.

Biogerontology 20050101

Function, attachment and synthesis of lipoic acid in Escherichia coli.

Advances in microbial physiology 20050101

Natural history of S-adenosylmethionine-binding proteins.

BMC structural biology 20050101

Lipoic acid - the drug of the future?

Pharmacological reports : PR 20050101

Effects of antioxidants on glutathione levels and clinical recovery from the malnutrition syndrome kwashiorkor--a pilot study.

Redox report : communications in free radical research 20050101

[Predictors of alpha-lipoic acid treatment efficacy in diabetic polyneuropathy of the lower limbs].

Terapevticheskii arkhiv 20050101

Potential risk factors for diabetic neuropathy: a case control study.

BMC neurology 20050101

Cell culture modeling to test therapies against hyperglycemia-mediated oxidative stress and injury.

Antioxidants & redox signaling 20050101

Proposed mechanisms for the induction of insulin resistance by oxidative stress.

Antioxidants & redox signaling 20050101

Diabetic retinopathy: mitochondrial dysfunction and retinal capillary cell death.

Antioxidants & redox signaling 20050101

The effects of alpha-lipoic acid on nitric oxide synthetase dispersion in penile function in streptozotocin-induced diabetic rats.

International journal of tissue reactions 20050101

A review of antioxidants and Alzheimer's disease.

Annals of clinical psychiatry : official journal of the American Academy of Clinical Psychiatrists 20050101

[Lipoic acid: characteristics and therapeutic application].

Postepy higieny i medycyny doswiadczalnej (Online) 20050101

Synthesis and preliminary in vitro evaluation of 5'-O-esters of 2'-deoxyadenosine and 2-chloro-2'-deoxyadenosine with alpha-lipoic acid as potential prodrugs.

Acta poloniae pharmaceutica 20050101

Differential activity of lipoic acid enantiomers in cell culture.

Journal of herbal pharmacotherapy 20050101

Transdermal delivery of amino acids and antioxidants enhance collagen synthesis: in vivo and in vitro studies.

Connective tissue research 20050101

[Alpha-lipoic--dihydrolipoic acids--active bioantioxidant and bioregulatory system].

Ukrains'kyi biokhimichnyi zhurnal (1999 ) 20050101

Effect of alpha lipoic acid, melatonin and trans resveratrol on intracerebroventricular streptozotocin induced spatial memory deficit in rats.

Indian journal of physiology and pharmacology 20050101

Therapy of hearing disorders - conservative procedures.

GMS current topics in otorhinolaryngology, head and neck surgery 20050101

Re-establishment of olfactory and taste functions.

GMS current topics in otorhinolaryngology, head and neck surgery 20050101

Protective effect of DL-alpha-lipoic acid on cyclophosphamide induced oxidative cardiac injury.

Chemico-biological interactions 20041230

[Evidence-based pharmacotherapy of neuropathic pain syndromes].

MMW Fortschritte der Medizin 20041209

Evidence against redox regulation of energy homoeostasis in humans at high altitude.

Clinical science (London, England : 1979) 20041201

Protective effect of DL-alpha-lipoic acid in cyclophosphamide induced oxidative injury in rat testis.

Reproductive toxicology (Elmsford, N.Y.) 20041201

Effect of long-term administration of alpha-lipoic acid on retinal capillary cell death and the development of retinopathy in diabetic rats.

Diabetes 20041201

Prevention and treatment of macroangiopathy: focusing on oxidative stress.

Diabetes research and clinical practice 20041201

Alpha-lipoic acid, an anti-obesity agent?

Expert opinion on investigational drugs 20041201

Effects of lipoic acid and a reduced-calorie diet on skin flap survival in a rat model.

Plastic and reconstructive surgery 20041201

High glucose decreases intracellular glutathione concentrations and upregulates inducible nitric oxide synthase gene expression in intestinal epithelial cells.

Journal of molecular endocrinology 20041201

Antioxidative treatment prevents activation of death-receptor- and mitochondrion-dependent apoptosis in the hearts of diabetic rats.

Diabetologia 20041201

Remedial effect of DL-alpha-lipoic acid against adriamycin induced testicular lipid peroxidation.

Molecular and cellular biochemistry 20041201

Cardiac lipids and antioxidant status in high fructose rats and the effect of alpha-lipoic acid.

Nutrition, metabolism, and cardiovascular diseases : NMCD 20041201

Crystal structure of T-protein of the glycine cleavage system. Cofactor binding, insights into H-protein recognition, and molecular basis for understanding nonketotic hyperglycinemia.

The Journal of biological chemistry 20041126

Amino-terminal residues 1-45 of the Escherichia coli pyruvate dehydrogenase complex E1 subunit interact with the E2 subunit and are required for activity of the complex but not for reductive acetylation of the E2 subunit.

Biochemistry 20041109

Analysis of proteome and transcriptome of tumor necrosis factor alpha stimulated vascular smooth muscle cells with or without alpha lipoic acid.

Proteomics 20041101

Determination of lipoic acid in rat plasma by LC-MS/MS with electrospray ionization: assay development, validation and application to a pharamcokinetic study.

Biomedical chromatography : BMC 20041101

Alpha lipoic acid inhibits human T-cell migration: implications for multiple sclerosis.

Journal of neuroscience research 20041101

Burning mouth syndrome: the efficacy of lipoic acid on subgroups.

Journal of the European Academy of Dermatology and Venereology : JEADV 20041101

Alpha-lipoic acid is ineffective as a topical antioxidant for photoprotection of skin.

The Journal of investigative dermatology 20041101

Effective treatments for insulin resistance: trim the fat and douse the fire.

Trends in endocrinology and metabolism: TEM 20041101

Novosphingobium aromaticivorans: a potential initiator of primary biliary cirrhosis.

The American journal of gastroenterology 20041101

Lipoic acid attenuates hypertension and improves insulin sensitivity, kallikrein activity and nitrite levels in high fructose-fed rats.

Journal of comparative physiology. B, Biochemical, systemic, and environmental physiology 20041101

Delaying the mitochondrial decay of aging with acetylcarnitine.

Annals of the New York Academy of Sciences 20041101

Antioxidant effects of sulfur-containing amino acids.

Yonsei medical journal 20041031

Determination of lipoic acid in dietary supplement preparations by capillary electrophoresis.

Journal of biochemical and biophysical methods 20041029

Pyruvate dehydrogenase kinase isoform 2 activity stimulated by speeding up the rate of dissociation of ADP.

Biochemistry 20041026

Inhibitory effect of lipoic acid on firefly luciferase bioluminescence.

Biochemical and biophysical research communications 20041015

A supramolecular approach to the selective detection of dopamine in the presence of ascorbate.

Chemical communications (Cambridge, England) 20041007

Cancer-related anorexia/cachexia syndrome and oxidative stress: an innovative approach beyond current treatment.

Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 20041001

The effects of the antioxidant lipoic acid on beef longissimus bloom time.

Journal of animal science 20041001

R-lipoic acid inhibits mammalian pyruvate dehydrogenase kinase.

Free radical research 20041001

Synthesis of chroman analogues of lipoic acid and evaluation of their activity against reperfusion arrhythmias.

Bioorganic & medicinal chemistry 20040915

Interactions of exercise training and alpha-lipoic acid on insulin signaling in skeletal muscle of obese Zucker rats.

American journal of physiology. Endocrinology and metabolism 20040901

Regulation of ischemic cell death by the lipoic acid-palladium complex, Poly MVA, in gerbils.

Experimental neurology 20040901

Conformational stability and thermodynamic characterization of the lipoic acid bearing domain of human mitochondrial branched chain alpha-ketoacid dehydrogenase.

Protein science : a publication of the Protein Society 20040901

Alpha-lipoic acid does not acutely affect resistance and conduit artery function or oxidative stress in healthy men.

British journal of clinical pharmacology 20040901

Separation and recovery of intact gold-virus complex by agarose electrophoresis and electroelution: application to the purification of cowpea mosaic virus and colloidal gold complex.

Electrophoresis 20040901

Natural antioxidants and neurodegenerative diseases.

Frontiers in bioscience : a journal and virtual library 20040901

Redox and antioxidant systems of the malaria parasite Plasmodium falciparum.

Molecular microbiology 20040901

Neuroprotection by alpha-lipoic acid in streptozotocin-induced diabetes.

Biochemistry. Biokhimiia 20040901

Attenuation of chloroquine-induced renal damage by alpha-lipoic acid: possible antioxidant mechanism.

Renal failure 20040901

What do herbalists suggest to diabetic patients in order to improve glycemic control? Evaluation of scientific evidence and potential risks.

Acta diabetologica 20040901

Lipoic acid pretreatment attenuates ferric chloride-induced seizures in the rat.

Brain research 20040806

Alpha-Lipoic acid-based PPARgamma agonists for treating inflammatory skin diseases.

Archives of dermatological research 20040801

Purification, crystallization and preliminary crystallographic analysis of the glycine-cleavage system component T-protein from Pyrococcus horikoshii OT3.

Acta crystallographica. Section D, Biological crystallography 20040801

Pseudomonas aeruginosa-induced production of free radicals by IFNgamma plus TNFalpha-activated human endothelial cells: mechanism of host defense or of bacterial pathogenesis?

Immunology and cell biology 20040801

Effect of antioxidants and ACE inhibition on chemical modification of proteins and progression of nephropathy in the streptozotocin diabetic rat.

Diabetologia 20040801

alpha-Lipoic acid inhibits airway inflammation and hyperresponsiveness in a mouse model of asthma.

The Journal of allergy and clinical immunology 20040801

Alpha-lipoic acid mitigates insulin resistance in Goto-Kakizaki rats.

Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme 20040801

Cross-talk between thiamin diphosphate binding and phosphorylation loop conformation in human branched-chain alpha-keto acid decarboxylase/dehydrogenase.

The Journal of biological chemistry 20040730

Reduced cell replication and induction of apoptosis by advanced glycation end products in rat Schwann cells.

Biochemical and biophysical research communications 20040716

[Evidence-based management of diabetic polyneuropathy. 'Burning feet' alarm signal].

MMW Fortschritte der Medizin 20040708

Anti-obesity effects of alpha-lipoic acid mediated by suppression of hypothalamic AMP-activated protein kinase.

Nature medicine 20040701

Effects of a medium chain triglyceride oil mixture and alpha-lipoic acid diet on body composition, antioxidant status, and plasma lipid levels in the Golden Syrian hamster.

The Journal of nutritional biochemistry 20040701

The human malaria parasite Plasmodium falciparum has distinct organelle-specific lipoylation pathways.

Molecular microbiology 20040701

Cellular energy sensor balances the scales.

Nature medicine 20040701

Heme, iron, and the mitochondrial decay of ageing.

Ageing research reviews 20040701

Repression of oxidant-induced nuclear factor-kappaB activity mediates placental cytokine responses in gestational diabetes.

The Journal of clinical endocrinology and metabolism 20040701

L-carnitine and DL-alpha-lipoic acid reverse the age-related deficit in glutathione redox state in skeletal muscle and heart tissues.

Mechanisms of ageing and development 20040701

alpha-lipoic acid inhibits endotoxin-stimulated expression of iNOS and nitric oxide independent of the heat shock response in RAW 264.7 cells.

Free radical research 20040701

Effects of glutathione, N-acetyl-cysteine, α-lipoic acid and dihydrolipoic acid on the cytotoxicity of a 2-pyridylcarboxamidrazone antimycobacterial agent in human mononuclear leucocytes in vitro.

Environmental toxicology and pharmacology 20040701

Immunochemical identification of coenzyme Q0-dihydrolipoamide adducts in the E2 components of the alpha-ketoglutarate and pyruvate dehydrogenase complexes partially explains the cellular toxicity of coenzyme Q0.

The Journal of biological chemistry 20040625

Role of nutritional intervention in patients treated with radiotherapy for pelvic malignancy.

British journal of cancer 20040614

Surface structure and chemical switching of thioctic acid adsorbed on Au(111) as observed using near-edge X-ray absorption fine structure.

Langmuir : the ACS journal of surfaces and colloids 20040608

Self-assembled monolayers of dendritic polyglycerol derivatives on gold that resist the adsorption of proteins.

Chemistry (Weinheim an der Bergstrasse, Germany) 20040607

Selective modulation of antioxidant enzyme activities in host tissues during Rickettsia conorii infection.

Microbial pathogenesis 20040601

Enhancement of arsenic trioxide-induced apoptosis in renal cell carcinoma cells by L-buthionine sulfoximine.

International journal of oncology 20040601

Lipoyl synthase requires two equivalents of S-adenosyl-L-methionine to synthesize one equivalent of lipoic acid.

Biochemistry 20040601

Response of the senescent heart to stress: clinical therapeutic strategies and quest for mitochondrial predictors of biological age.

Annals of the New York Academy of Sciences 20040601

Alpha-lipoic acid increases Na+K+ATPase activity and reduces lipofuscin accumulation in discrete brain regions of aged rats.

Annals of the New York Academy of Sciences 20040601

Delaying the mitochondrial decay of aging.

Annals of the New York Academy of Sciences 20040601

Effects of alpha-lipoic acid supplementation on maternal diabetes-induced growth retardation and congenital anomalies in rat fetuses.

Molecular and cellular biochemistry 20040601

HFA1 encoding an organelle-specific acetyl-CoA carboxylase controls mitochondrial fatty acid synthesis in Saccharomyces cerevisiae.

The Journal of biological chemistry 20040521

Human mitochondrial thioredoxin reductase reduces cytochrome c and confers resistance to complex III inhibition.

Free radical biology & medicine 20040515

Xenobiotic-induced loss of tolerance in rabbits to the mitochondrial autoantigen of primary biliary cirrhosis is reversible.

Journal of immunology (Baltimore, Md. : 1950) 20040515

Influence of alpha-lipoic acid on lipid peroxidation and antioxidant defence system in blood of insulin-resistant rats.

Diabetes, obesity & metabolism 20040501

Cu2+ toxicity inhibition of mitochondrial dehydrogenases in vitro and in vivo.

Annals of neurology 20040501

Long-term treatment with antioxidants and a program of behavioral enrichment reduces age-dependent impairment in discrimination and reversal learning in beagle dogs.

Experimental gerontology 20040501

Lipoic acid as a potential therapy for chronic diseases associated with oxidative stress.

Current medicinal chemistry 20040501

The impact of alpha-lipoic acid, coenzyme Q10 and caloric restriction on life span and gene expression patterns in mice.

Free radical biology & medicine 20040415

Therapeutic efficacy of lipoic acid in combination with dimercaptosuccinic acid against lead-induced renal tubular defects and on isolated brush-border enzyme activities.

Chemico-biological interactions 20040415

Antioxidative treatment reverses imbalances of nitric oxide synthase isoform expression and attenuates tissue-cGMP activation in diabetic rats.

Biochemical and biophysical research communications 20040409

Plasma C-reactive protein concentrations in active and passive smokers: influence of antioxidant supplementation.

Journal of the American College of Nutrition 20040401

Lipoic acid is 10 times more toxic in cats than reported in humans, dogs or rats.

Journal of animal physiology and animal nutrition 20040401

The role of lipoic acid in the regulation of the redox status of wheat irrigated with 20% sea water.

Plant physiology and biochemistry : PPB 20040401

Regulation of mitochondrial transcription factor A expression by high glucose.

Annals of the New York Academy of Sciences 20040401

Prevention and partial reversal of diabetes-induced changes in enteric nerves of the rat ileum by combined treatment with alpha-lipoic acid and evening primrose oil.

Autonomic neuroscience : basic & clinical 20040331

Lipoic acid protects efficiently only against a specific form of peroxynitrite-induced damage.

The Journal of biological chemistry 20040312

Antioxidant intervention does not affect the response of plasma erythropoietin to short-term normobaric hypoxia in humans.

Journal of applied physiology (Bethesda, Md. : 1985) 20040301

(R)-alpha-lipoic acid reverses the age-related loss in GSH redox status in post-mitotic tissues: evidence for increased cysteine requirement for GSH synthesis.

Archives of biochemistry and biophysics 20040301

Alpha-lipoic acid is effective in prevention and treatment of experimental autoimmune encephalomyelitis.

Journal of neuroimmunology 20040301

Synthesis and characterization of new and potent alpha-lipoic acid derivatives.

Bioorganic & medicinal chemistry 20040301

Antioxidant supplementation normalizes elevated protein kinase C activity in the proximal tubules of old rats.

Experimental biology and medicine (Maywood, N.J.) 20040301

A role for supplements in optimizing health: the metabolic tune-up.

Archives of biochemistry and biophysics 20040301

(r)-, but not (s)-alpha lipoic acid stimulates deficient brain pyruvate dehydrogenase complex in vascular dementia, but not in Alzheimer dementia.

Journal of neural transmission (Vienna, Austria : 1996) 20040301

The role of chronic inflammation in cardiovascular disease and its regulation by nutrients.

Alternative medicine review : a journal of clinical therapeutic 20040301

Effect of lipoic acid on the oxidoreductive status of red blood cells in rats subject to oxidative stress by chronic administration of adriamycin.

Human & experimental toxicology 20040301

alpha-Lipoic acid ameliorates altered colonic contractility and intestinal transit in STZ-diabetic rats.

Indian journal of experimental biology 20040301

[Effects of DL-alpha-lipoic acid on the experimentally induced diabetic cataract in rats].

[Zhonghua yan ke za zhi] Chinese journal of ophthalmology 20040301

Complications & side effects. Supplements and CD4+ counts: study finds surprising results.

TreatmentUpdate 20040301

Identification of bladder cancer antigens recognized by IgG antibodies of a patient with metastatic bladder cancer.

International journal of cancer 20040220

Lipoic acid-dependent oxidative catabolism of alpha-keto acids in mitochondria provides evidence for branched-chain amino acid catabolism in Arabidopsis.

Plant physiology 20040201

Effect of R(+)alpha-lipoic acid on pyruvate metabolism and fatty acid oxidation in rat hepatocytes.

Metabolism: clinical and experimental 20040201

Treatment of symptomatic diabetic polyneuropathy with the antioxidant alpha-lipoic acid: a meta-analysis.

Diabetic medicine : a journal of the British Diabetic Association 20040201

DNA-conjugated polymers for self-assembled DNA chip fabrication.

Analytical sciences : the international journal of the Japan Society for Analytical Chemistry 20040201

NADPH-cytochrome P-450 reductase is involved in flunitrazepam reductive metabolism in Hep G2 and Hep 3B cells.

Journal of toxicology and environmental health. Part A 20040123

Photoinduced interactions between oxidized and reduced lipoic acid and riboflavin (vitamin B2).

Chemphyschem : a European journal of chemical physics and physical chemistry 20040123

Diabetic neuropathy: an intensive review.

American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20040115

Targets of stress-induced oxidative damage in plant mitochondria and their impact on cell carbon/nitrogen metabolism.

Journal of experimental botany 20040101

Antioxidants effectively prevent oxidation-induced protein damage in OLN 93 cells.

Archives of biochemistry and biophysics 20040101

Burning Mouth Syndrome: open trial of psychotherapy alone, medication with alpha-lipoic acid (thioctic acid), and combination therapy.

Medicina oral : organo oficial de la Sociedad Espanola de Medicina Oral y de la Academia Iberoamericana de Patologia y Medicina Bucal 20040101

Combined efficacies of lipoic acid and 2,3-dimercaptosuccinic acid against lead-induced lipid peroxidation in rat liver.

The Journal of nutritional biochemistry 20040101

Protective effect of alpha-lipoic acid against chloroquine-induced hepatotoxicity in rats.

Journal of applied toxicology : JAT 20040101

Alpha lipoic acid for dementia.

The Cochrane database of systematic reviews 20040101

Nitrosative injury and antioxidant therapy in the management of diabetic neuropathy.

Journal of investigative medicine : the official publication of the American Federation for Clinical Research 20040101

Development of a sustained release dosage form for alpha-lipoic acid. I. Design and in vitro evaluation.

Drug development and industrial pharmacy 20040101

Development of a sustained release dosage form for alpha-lipoic acid. II. Evaluation in human volunteers.

Drug development and industrial pharmacy 20040101

[Possibilities and perspectives of berlition usage in the treatment of alcohol polyneuropathy].

Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova 20040101

Molecular and genetic mechanisms of floral control.

The Plant cell 20040101

[Treatment of Chagas disease with benznidazole and thioctic acid].

Medicina 20040101

Dihydrolipoic acid lowers the redox activity of transition metal ions but does not remove them from the active site of enzymes.

Redox report : communications in free radical research 20040101

Unraveling the pathway of lipoic acid biosynthesis.

Chemistry & biology 20040101

Clinical experience with thioctacid (thioctic acid) in the treatment of distal symmetric polyneuropathy in Korean diabetic patients.

Journal of diabetes and its complications 20040101

Prior experience, antioxidants, and mitochondrial cofactors improve cognitive function in aged beagles.

Veterinary therapeutics : research in applied veterinary medicine 20040101

[Vitamin sufficiency of young basketball players].

Voprosy pitaniia 20040101

On becoming a nutritional biochemist.

Annual review of nutrition 20040101

Effect of fidarestat and alpha-lipoic acid on diabetes-induced epineurial arteriole vascular dysfunction.

Experimental diabesity research 20040101

The effect of cytoprotective agents in platinum anticancer therapy.

Metal ions in biological systems 20040101

Reactions of nifurtimox with critical sulfhydryl-containing biomolecules: their potential toxicological relevance.

Journal of applied toxicology : JAT 20040101

Antioxidant defense in Plasmodium falciparum--data mining of the transcriptome.

Malaria journal 20040101

The use of ozone as an oxidizing agent to evaluate antioxidant activities of natural substrates.

Skin pharmacology and physiology 20040101

[Device laboratory and postmortem parallels in alcoholic hepatitis during combined therapy using thioctic (alpha-lipoic) acid].

Klinicheskaia meditsina 20040101

Effect of alpha-lipoic acid on lipid profile in rats fed a high-fructose diet.

Experimental diabesity research 20040101

Role of reactive oxygen species in bradykinin-induced proliferation of vascular smooth muscle cells.

Biological research 20040101

Treatment of diabetic polyneuropathy with alpha-lipoic acid is evidence based.

Romanian journal of internal medicine = Revue roumaine de medecine interne 20040101

Alpha-lipoic acid in the treatment of autonomic diabetic neuropathy (controlled, randomized, open-label study).

Romanian journal of internal medicine = Revue roumaine de medecine interne 20040101

[Complex treatment of patients with the diabetic foot].

Klinicheskaia meditsina 20040101

Protective activity of hesperidin and lipoic acid against sodium arsenite acute toxicity in mice.

Toxicologic pathology 20040101

Stability study of lipoic acid in the presence of vitamins A and E in o/w emulsions for cosmetic application.

Journal of cosmetic science 20040101

Influence of treatment of diabetic rats with combinations of pycnogenol, beta-carotene, and alpha-lipoic acid on parameters of oxidative stress.

Journal of biochemical and molecular toxicology 20040101

The role of antioxidant micronutrients in the prevention of diabetic complications.

Treatments in endocrinology 20040101

Fructose diet-induced skin collagen abnormalities are prevented by lipoic acid.

Experimental diabesity research 20040101

[Glutathione: its biosynthesis, induction agents and concentrations in selected diseases].

Medycyna pracy 20040101

Thioctic acid for patients with symptomatic diabetic polyneuropathy: a critical review.

Treatments in endocrinology 20040101

The cosmetic treatment of wrinkles.

Journal of cosmetic dermatology 20040101

[Changes in antioxidant capacity of the guinea pig exposed to noise and the protective effect of alpha-lipoic acid against acoustic trauma].

Sheng li xue bao : [Acta physiologica Sinica] 20031225

Detection of metal ions using ion-channel sensor based on self-assembled monolayer of thioctic acid.

Talanta 20031223

Covalent immobilization of beta-galactosidase onto a gold-coated magnetoelastic transducer via a self-assembled monolayer: toward a magnetoelastic biosensor.

Analytical chemistry 20031215

Irwin C. Gunsalus, versatile and creative scientist.

Biochemical and biophysical research communications 20031205

Metabolism of vitamins in microbes and mammals.

Biochemical and biophysical research communications 20031205

Prophylaxis against lipopolysaccharide-induced liver injuries by lipoic acid in rats.

Pharmacological research 20031201

Oxidative stress in the pathogenesis of experimental mesangial proliferative glomerulonephritis.

American journal of physiology. Renal physiology 20031201

Effect of single and combined supply of glutamine, glycine, N-acetylcysteine, and R,S-alpha-lipoic acid on glutathione content of myelomonocytic cells.

Clinical nutrition (Edinburgh, Scotland) 20031201

Kinetic spectrophotometric determination of some sulfur containing compounds in pharmaceutical preparations and human serum.

Farmaco (Societa chimica italiana : 1989) 20031201

Radiation-induced cyclooxygenase 2 up-regulation is dependent on redox status in prostate cancer cells.

Radiation research 20031201

Anti-AGEing defences against Alzheimer's disease.

Biochemical Society transactions 20031201

Vascular endothelial dysfunction in aging: loss of Akt-dependent endothelial nitric oxide synthase phosphorylation and partial restoration by (R)-alpha-lipoic acid.

Biochemical Society transactions 20031201

Salt-induced hypertension in WKY rats: prevention by alpha-lipoic acid supplementation.

Molecular and cellular biochemistry 20031201

Prophylactic action of lipoic acid on oxidative stress and growth performance in broilers at risk of developing ascites syndrome.

Avian pathology : journal of the W.V.P.A 20031201

Assembly of the covalent linkage between lipoic acid and its cognate enzymes.

Chemistry & biology 20031201

Autoreactivity to lipoate and a conjugated form of lipoate in primary biliary cirrhosis.

Gastroenterology 20031201

Activation of JNK in sensory neurons protects against sensory neuron cell death in diabetes and on exposure to glucose/oxidative stress in vitro.

Annals of the New York Academy of Sciences 20031201

Vitamin D enhances caspase-dependent and independent TNF-induced breast cancer cell death: the role of reactive oxygen species.

Annals of the New York Academy of Sciences 20031201

Dihydrolipoic acid inhibits 15-lipoxygenase-dependent lipid peroxidation.

Free radical biology & medicine 20031115

Copper(I) pseudorotaxane monolayers assembled on gold electrodes.

Inorganic chemistry 20031103

Plasma kinetics, metabolism, and urinary excretion of alpha-lipoic acid following oral administration in healthy volunteers.

Journal of clinical pharmacology 20031101

Beta-cyclodextrin-based ferrocene-imprinted gold electrodes.

Analytical chemistry 20031101

Advanced glycation endproducts induce changes in glucose consumption, lactate production, and ATP levels in SH-SY5Y neuroblastoma cells by a redox-sensitive mechanism.

Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 20031101

Alpha-lipoic acid treatment prevents the diabetes-induced attenuation of the afferent limb of the baroreceptor reflex in rats.

Autonomic neuroscience : basic & clinical 20031031

Induction of endogenous antioxidants and phase 2 enzymes by alpha-lipoic acid in rat cardiac H9C2 cells: protection against oxidative injury.

Biochemical and biophysical research communications 20031024

Listeria intracellular growth and virulence require host-derived lipoic acid.

Science (New York, N.Y.) 20031017

Alpha-lipoic acid preconditioning reduces ischemia-reperfusion injury of the rat liver via the PI3-kinase/Akt pathway.

American journal of physiology. Gastrointestinal and liver physiology 20031001

Antioxidant agents are effective in inducing lymphocyte progression through cell cycle in advanced cancer patients: assessment of the most important laboratory indexes of cachexia and oxidative stress.

Journal of molecular medicine (Berlin, Germany) 20031001

Glucose transporter type1 (GLUT-1) deficiency.

Brain & development 20031001

An alpha-lipoic acid-vitamin E mixture reduces post-embolism lipid peroxidation, cerebral infarction, and neurological deficit in rats.

Neuroscience research 20031001

Targeting cellular energy production in neurological disorders.

Expert opinion on investigational drugs 20031001

Potent antioxidant improves diabetic nerve damage.

Mayo Clinic women's healthsource 20031001

Creatine monohydrate supplemented in swine finishing diets and fresh pork quality: III. Evaluating the cumulative effect of creatine monohydrate and alpha-lipoic acid.

Journal of animal science 20031001

Age-related increase in 4-hydroxynonenal adduction to rat heart alpha-ketoglutarate dehydrogenase does not cause loss of its catalytic activity.

Antioxidants & redox signaling 20031001

Randomized, placebo-controlled, double blind study on the clinical efficacy of a cream containing 5% alpha-lipoic acid related to photoageing of facial skin.

The British journal of dermatology 20031001

Vitamin C recycling is enhanced in the adaptive response to leptin-induced oxidative stress in keratinocytes.

The Journal of investigative dermatology 20031001

Linoleic acid and antioxidants protect against DNA damage and apoptosis induced by palmitic acid.

Mutation research 20030929

Alpha-lipoic acid inhibits adipocyte differentiation by regulating pro-adipogenic transcription factors via mitogen-activated protein kinase pathways.

The Journal of biological chemistry 20030912

Facilitated interaction between the pyruvate dehydrogenase kinase isoform 2 and the dihydrolipoyl acetyltransferase.

The Journal of biological chemistry 20030905

Alpha-lipoic acid decreases thiol reactivity of the insulin receptor and protein tyrosine phosphatase 1B in 3T3-L1 adipocytes.

Biochemical pharmacology 20030901

Free radical scavengers improve the impaired endothelium-dependent responses in aorta and kidneys of diabetic rabbits.

Diabetes research and clinical practice 20030901

Interactions of conjugated linoleic acid and lipoic acid on insulin action in the obese Zucker rat.

Metabolism: clinical and experimental 20030901

Effect of DL-alpha-lipoic acid on the status of lipid peroxidation and lipids in aged rats.

The journals of gerontology. Series A, Biological sciences and medical sciences 20030901

Molecular mechanisms, diagnosis, and rational approaches to management of and therapy for Charcot-Marie-Tooth disease and related peripheral neuropathies.

Journal of investigative medicine : the official publication of the American Federation for Clinical Research 20030901

A dual action of alpha-lipoic acid in the brain: an electrophysiological evaluation.

Arquivos de neuro-psiquiatria 20030901

Effect of alpha-lipoic acid combined with creatine monohydrate on human skeletal muscle creatine and phosphagen concentration.

International journal of sport nutrition and exercise metabolism 20030901

Lipoic acid restores antioxidant system in tissues of hyperinsulinaemic rats.

The Indian journal of medical research 20030901

Effects of dihydrolipoic acid (DHLA), α-lipoic acid. N-acetyl cysteine and ascorbate on xenobiotic-mediated methaemoglobin formation in human erythrocytes in vitro.

Environmental toxicology and pharmacology 20030901

Futile cycling of intermediates of fatty acid biosynthesis toward peroxisomal beta-oxidation in Saccharomyces cerevisiae.

The Journal of biological chemistry 20030829

Vitamin D enhances caspase-dependent and -independent TNFalpha-induced breast cancer cell death: The role of reactive oxygen species and mitochondria.

International journal of cancer 20030820

Synthesis and antioxidant efficiency of a new amphiphilic spin-trap derived from PBN and lipoic acid.

Bioorganic & medicinal chemistry letters 20030818

Lipoic acid supplementation prevents angiotensin II-induced renal injury.

Kidney international 20030801

Experimental therapeutics in Huntington's disease: are models useful for therapeutic trials?

Current opinion in neurology 20030801

Nuclear factor kappa B: a potential target for anti-HIV chemotherapy.

Current medicinal chemistry 20030801

Effects of antioxidants in diabetes-induced oxidative stress in the glomeruli of diabetic rats.

Journal of the American Society of Nephrology : JASN 20030801

Effect of alpha lipoic acid on intracerebroventricular streptozotocin model of cognitive impairment in rats.

European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology 20030801

Nutritional cofactor treatment in mitochondrial disorders.

Journal of the American Dietetic Association 20030801

[Therapy of olfactory loss].

Laryngo- rhino- otologie 20030801

Oxaliplatin-safety profile: neurotoxicity.

Seminars in oncology 20030801

[Acute painful neuropathy at the initial period of effective insulin therapy].

Polskie Archiwum Medycyny Wewnetrznej 20030801

Lipoic acid as a potential first agent for protection from mycotoxins and treatment of mycotoxicosis.

Archives of environmental health 20030801

Apicomplexan parasites contain a single lipoic acid synthase located in the plastid.

FEBS letters 20030717

Copper toxicity, oxidative stress, and antioxidant nutrients.

Toxicology 20030715

Effects of alpha-lipoic acid on impaired gastric fundus innervation in diabetic rats.

Free radical biology & medicine 20030715

Demonstration of labeless detection of food pathogens using electrochemical redox probe and screen printed gold electrodes.

Biosensors & bioelectronics 20030701

Essential 110Cys in active site of membrane-associated prostaglandin E synthase-2.

Biochemical and biophysical research communications 20030627

Dykellic acid inhibits phorbol myristate acetate-induced matrix metalloproteinase-9 expression by inhibiting nuclear factor kappa B transcriptional activity.

Cancer research 20030615

Human enzymes involved in the metabolic activation of the environmental contaminant 3-nitrobenzanthrone: evidence for reductive activation by human NADPH:cytochrome p450 reductase.

Cancer research 20030601

Acute glucose deprivation leads to apoptosis in a cell model of acute diabetic neuropathy.

Journal of the peripheral nervous system : JPNS 20030601

Biological radical sulfur insertion reactions.

Chemical reviews 20030601

Evaluation of the effect of lipoic acid administered along with gentamicin in rats rendered bacteremic.

Molecular and cellular biochemistry 20030601

Protection against amyloid beta peptide and iron/hydrogen peroxide toxicity by alpha lipoic acid.

Journal of Alzheimer's disease : JAD 20030601

A preliminary evaluation of a novel method to monitor a triple antioxidant combination (vitamins E, C and α-lipoic acid) in diabetic volunteers using in vitro methaemoglobin formation.

Environmental toxicology and pharmacology 20030601

Prevention of oxidant-induced cell death by lysosomotropic iron chelators.

Free radical biology & medicine 20030515

Immunization with a xenobiotic 6-bromohexanoate bovine serum albumin conjugate induces antimitochondrial antibodies.

Journal of immunology (Baltimore, Md. : 1950) 20030515

Melatonin, xanthurenic acid, resveratrol, EGCG, vitamin C and alpha-lipoic acid differentially reduce oxidative DNA damage induced by Fenton reagents: a study of their individual and synergistic actions.

Journal of pineal research 20030501

NAD(P)H oxidase activation by angiotensin II is dependent on p42/44 ERK-MAPK pathway activation in rat's vascular smooth muscle cells.

Journal of hypertension 20030501

New insights on oxidative stress and diabetic complications may lead to a 'causal' antioxidant therapy.

Diabetes care 20030501

IRS1 degradation and increased serine phosphorylation cannot predict the degree of metabolic insulin resistance induced by oxidative stress.

Diabetologia 20030501

Protective role of DLalpha-lipoic acid against adriamycin-induced cardiac lipid peroxidation.

Human & experimental toxicology 20030501

Toxic metals and antioxidants: Part II. The role of antioxidants in arsenic and cadmium toxicity.

Alternative medicine review : a journal of clinical therapeutic 20030501

Physico-chemical properties and spectrophotometric determination of biologically active 1-alkyl-2-(2-pyridyl)pyridinium bromides.

Die Pharmazie 20030501

Prophylactic effect of lipoic acid against adriamycin-induced peroxidative damages in rat kidney.

Renal failure 20030501

Effects of alpha-lipoic acid on biomarkers of oxidative stress in streptozotocin-induced diabetic rats.

The Journal of nutritional biochemistry 20030501

Protective effect of lipoic acid on adriamycin induced lipid peroxidation in rat kidney.

Molecular and cellular biochemistry 20030501

The influence of lipoic acid on adriamycin induced nephrotoxicity in rats.

Molecular and cellular biochemistry 20030501

Inhibition of oxygen radical formation by methylene blue, aspirin, or alpha-lipoic acid, prevents bacterial-lipopolysaccharide-induced fever.

Molecular and cellular biochemistry 20030501

The influence of lipoic acid on adriamycin-induced hyperlipidemic nephrotoxicity in rats.

Molecular and cellular biochemistry 20030501

Reduction of inclusion body pathology in ApoE-deficient mice fed a combination of antioxidants.

Free radical biology & medicine 20030415

Modulation of extracellular homocysteine concentration in human cell lines.

Clinica chimica acta; international journal of clinical chemistry 20030401

Radiation response of cells during altered protein thiol redox.

Radiation research 20030401

Glycated albumin increases oxidative stress, activates NF-kappa B and extracellular signal-regulated kinase (ERK), and stimulates ERK-dependent transforming growth factor-beta 1 production in macrophage RAW cells.

The Journal of laboratory and clinical medicine 20030401

Effect of iron-sulfur cluster assembly proteins on the expression of Escherichia coli lipoic acid synthase.

Protein expression and purification 20030401

Exercise training and antioxidants: relief from oxidative stress and insulin resistance.

Exercise and sport sciences reviews 20030401

Combined efficacies of lipoic acid and meso-2,3-dimercaptosuccinic acid on lead-induced erythrocyte membrane lipid peroxidation and antioxidant status in rats.

Human & experimental toxicology 20030401

Transdermal delivery of two antioxidants from different cosmetic formulations.

International journal of cosmetic science 20030401

Direct evidence for recycling of myeloperoxidase-catalyzed phenoxyl radicals of a vitamin E homologue, 2,2,5,7,8-pentamethyl-6-hydroxy chromane, by ascorbate/dihydrolipoate in living HL-60 cells.

Biochimica et biophysica acta 20030317

[Polyneuropathy--therapy].

Deutsche medizinische Wochenschrift (1946) 20030314

Alpha-lipoic acid induces p27Kip-dependent cell cycle arrest in non-transformed cell lines and apoptosis in tumor cell lines.

Journal of cellular physiology 20030301

The Escherichia coli lipB gene encodes lipoyl (octanoyl)-acyl carrier protein:protein transferase.

Journal of bacteriology 20030301

The antioxidants alpha-lipoic acid and N-acetylcysteine reverse memory impairment and brain oxidative stress in aged SAMP8 mice.

Journal of neurochemistry 20030301

Transport of biotin in human keratinocytes.

The Journal of investigative dermatology 20030301

Characterization of retinal leukostasis and hemodynamics in insulin resistance and diabetes: role of oxidants and protein kinase-C activation.

Diabetes 20030301

The sensory symptoms of diabetic polyneuropathy are improved with alpha-lipoic acid: the SYDNEY trial.

Diabetes care 20030301

Lipoic acid prevents hypertension, hyperglycemia, and the increase in heart mitochondrial superoxide production.

American journal of hypertension 20030301

2-Oxo acid dehydrogenase complexes in redox regulation.

European journal of biochemistry 20030301

Graded sensitiveness of the various retinal neuron populations on the glyoxal-mediated formation of advanced glycation end products and ways of protection.

Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie 20030301

Protective effect of green tea polyphenol (-)-epigallocatechin gallate and other antioxidants on lipid peroxidation in gerbil brain homogenates.

Phytotherapy research : PTR 20030301

Catalysis of diaphorase reactions by Mycobacterium tuberculosis lipoamide dehydrogenase occurs at the EH4 level.

Biochemistry 20030225

Photoprotection by antioxidants against UVB-radiation-induced damage in pig skin organ culture.

Radiation research 20030201

Amelioration of docetaxel/cisplatin induced polyneuropathy by alpha-lipoic acid.

Annals of oncology : official journal of the European Society for Medical Oncology 20030201

Alpha lipoic acid changes iron uptake and storage in lens epithelial cells.

Experimental eye research 20030201

Advanced glycation endproducts cause lipid peroxidation in the human neuronal cell line SH-SY5Y.

Journal of Alzheimer's disease : JAD 20030201

Justification for antioxidant preconditioning (or how to protect insulin-mediated actions under oxidative stress).

Journal of biosciences 20030201

Early oxidative stress in the diabetic kidney: effect of DL-alpha-lipoic acid.

Free radical biology & medicine 20030115

Hemoprotein-mediated reduction of nitrated DNA bases in the presence of reducing agents.

Free radical biology & medicine 20030115

Mast cells mediate the microvascular inflammatory response to systemic hypoxia.

Journal of applied physiology (Bethesda, Md. : 1985) 20030101

Reactive oxygen species are involved in the stimulation of the mitochondrial permeability transition by dihydrolipoate.

Biochemical pharmacology 20030101

The effectiveness of treatments of diabetic autonomic neuropathy is not the same in autonomic nerves supplying different organs.

Diabetes 20030101

Botanicals and dietary supplements in diabetic peripheral neuropathy.

The Journal of the American Board of Family Practice 20030101

Synthesis and pharmacological evaluation of new 1,2-dithiolane based antioxidants.

European journal of medicinal chemistry 20030101

[Lipoylation of the proteins having lipoic acid as a prosthetic group].

Seikagaku. The Journal of Japanese Biochemical Society 20030101

Preventing superoxide formation in epineurial arterioles of the sciatic nerve from diabetic rats restores endothelium-dependent vasodilation.

Free radical research 20030101

Bioenergetic approaches for neuroprotection in Parkinson's disease.

Annals of neurology 20030101

Comparison of the carcinogenic potential of streptozotocin by polarography and alkaline elution.

Neoplasma 20030101

In vitro neuroprotection against oxidative stress by pre-treatment with a combination of dihydrolipoic acid and phenyl-butyl nitrones.

Neurotoxicity research 20030101

Vitamin C, glutathione, or lipoic acid did not decrease brain or kidney mercury in rats exposed to mercury vapor.

Journal of toxicology. Clinical toxicology 20030101

Lipoic acid: a multifunctional antioxidant.

BioFactors (Oxford, England) 20030101

Redox regulation of mitochondrial permeability transition: effects of uncoupler, lipoic acid and its positively charged analog LA-plus and selenium.

BioFactors (Oxford, England) 20030101

Cocaine, not morphine, causes the generation of reactive oxygen species and activation of NF-kappaB in transiently cotransfected heart cells.

Cardiovascular toxicology 20030101

Subcutaneous interleukin-2 in combination with medroxyprogesterone acetate and antioxidants in advanced cancer responders to previous chemotherapy: phase II study evaluating clinical, quality of life, and laboratory parameters.

Journal of experimental therapeutics & oncology 20030101

Protective effect of lipoic acid against hydrogen peroxide in yeast cells.

Toxicology in vitro : an international journal published in association with BIBRA 20030101

Antioxidants: a possible role in kidney protection.

Kidney & blood pressure research 20030101

Redox balance in patients with Down's syndrome before and after dietary supplementation with alpha-lipoic acid and L-cysteine.

International journal of clinical pharmacology research 20030101

Redox control, redox signaling, and redox homeostasis in plant cells.

International review of cytology 20030101

Acrolein inhibits NADH-linked mitochondrial enzyme activity: implications for Alzheimer's disease.

Neurotoxicity research 20030101

ADP- and oligomycin-sensitive redox behavior of F0 b thiol in ATPsynthase depends on neighbored primary structure: investigations using 14-C-labeled alpha lipoic acid.

BioFactors (Oxford, England) 20030101

The role of free radicals and plasmatic antioxidant in Ménière's syndrome.

The international tinnitus journal 20030101

Antioxidant activities of novel alpha-lipoic acid derivatives: N-(6, 8-dimercaptooctanoyl)-2-aminoethanesulfonate- and N-(6, 8-dimercaptooctanoyl)-L-aspartate-zinc complex.

Research communications in molecular pathology and pharmacology 20030101

Current and future strategies for the management of diabetic neuropathy.

Treatments in endocrinology 20030101

Histidine 407, a phantom residue in the E1 subunit of the Escherichia coli pyruvate dehydrogenase complex, activates reductive acetylation of lipoamide on the E2 subunit. An explanation for conservation of active sites between the E1 subunit and transketolase.

Biochemistry 20021231

Geometrical isomerism of monounsaturated fatty acids: thiyl radical catalysis and influence of antioxidant vitamins.

Free radical biology & medicine 20021215

The lipoamide dehydrogenase from Mycobacterium tuberculosis permits the direct observation of flavin intermediates in catalysis.

Biochemistry 20021210

Inhibition of LPS-induced nitric oxide and TNF-alpha production by alpha-lipoic acid in rat Kupffer cells and in RAW 264.7 murine macrophages.

Immunology and cell biology 20021201

Activation of tubular epithelial cells in diabetic nephropathy.

Diabetes 20021201

Alpha-lipoic acid ameliorates myocardial toxicity induced by doxorubicin.

Pharmacological research 20021201

Capillary zone electrophoresis study of cyclodextrin--lipoic acid host-guest interaction.

Electrophoresis 20021201

Modulation of microphthalmia-associated transcription factor gene expression alters skin pigmentation.

The Journal of investigative dermatology 20021201

Mercury toxicity and antioxidants: Part 1: role of glutathione and alpha-lipoic acid in the treatment of mercury toxicity.

Alternative medicine review : a journal of clinical therapeutic 20021201

Idiopathic dysgeusia; an open trial of alpha lipoic acid (ALA) therapy.

International journal of oral and maxillofacial surgery 20021201

Acoustic coupling of transverse waves as a mechanism for the label-free detection of protein-small molecule interactions.

The Analyst 20021201

Neurochemical changes related to ageing in the rat brain and the effect of DL-alpha-lipoic acid.

Experimental gerontology 20021201

Glucose transporter 1 deficiency syndrome and other glycolytic defects.

Journal of child neurology 20021201

Role of topical and nutritional supplement to modify the oxidative stress.

International journal of cosmetic science 20021201

Micronutrient cofactor research with extensions to applications.

Nutrition research reviews 20021201

Effects of intraperitoneally administered lipoic acid, vitamin E, and linalool on the level of total lipid and fatty acids in guinea pig brain with oxidative stress induced by H2O2.

Journal of biochemistry and molecular biology 20021130

Environmental stress causes oxidative damage to plant mitochondria leading to inhibition of glycine decarboxylase.

The Journal of biological chemistry 20021108

Alpha-lipoic acid protects the retina against ischemia-reperfusion.

Neuropharmacology 20021101

Lipoic acid in the treatment of smell dysfunction following viral infection of the upper respiratory tract.

The Laryngoscope 20021101

Screening of ubiquitous plant constituents for COX-2 inhibition with a scintillation proximity based assay.

Journal of natural products 20021101

Folding kinetics of the lipoic acid-bearing domain of human mitochondrial branched chain alpha-ketoacid dehydrogenase complex.

FEBS letters 20021023

Selective inactivation of redox-sensitive mitochondrial enzymes during cardiac reperfusion.

Archives of biochemistry and biophysics 20021015

The C-terminal hinge region of lipoic acid-bearing domain of E2b is essential for domain interaction with branched-chain alpha-keto acid dehydrogenase kinase.

The Journal of biological chemistry 20021004

Matrix protein glycation impairs agonist-induced intracellular Ca2+ signaling in endothelial cells.

Journal of cellular physiology 20021001

Interactions of lipoic acid radical cations with vitamins C and E analogue and hydroxycinnamic acid derivatives.

Archives of biochemistry and biophysics 20021001

Thioltransferase (glutaredoxin) mediates recovery of motor neurons from excitotoxic mitochondrial injury.

The Journal of neuroscience : the official journal of the Society for Neuroscience 20021001

Oxidative stress and stress-activated signaling pathways: a unifying hypothesis of type 2 diabetes.

Endocrine reviews 20021001

Bacterial cysteine desulfurases: their function and mechanisms.

Applied microbiology and biotechnology 20021001

Inactivation of the 2-oxo acid dehydrogenase complexes upon generation of intrinsic radical species.

European journal of biochemistry 20021001

Pre-treatment with R-lipoic acid alleviates the effects of GSH depletion in PC12 cells: implications for Parkinson's disease therapy.

Neurotoxicology 20021001

Alpha lipoic acid inhibits T cell migration into the spinal cord and suppresses and treats experimental autoimmune encephalomyelitis.

Journal of neuroimmunology 20021001

The AGE inhibitor pyridoxamine inhibits development of retinopathy in experimental diabetes.

Diabetes 20020901

Development of a new assay for the screening of hypochlorous acid scavengers based on reversed-phase high-performance liquid chromatography.

Biomedical chromatography : BMC 20020901

Burning mouth syndrome (BMS): an open trial of comparative efficacy of alpha-lipoic acid (thioctic acid) with other therapies.

Minerva stomatologica 20020901

Lead induced oxidative damage and its response to combined administration of alpha-lipoic acid and succimers in rats.

Toxicology 20020815

Lipoyl dehydrogenase catalyzes reduction of nitrated DNA and protein adducts using dihydrolipoic acid or ubiquinol as the cofactor.

Chemico-biological interactions 20020815

Alpha-lipoic acid prevents ethanol-induced protein oxidation in mouse hippocampal HT22 cells.

Neuroscience letters 20020809

Glutaredoxins catalyze the reduction of glutathione by dihydrolipoamide with high efficiency.

Biochemical and biophysical research communications 20020802

Effective treatment of oxaliplatin-induced cumulative polyneuropathy with alpha-lipoic acid.

Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20020801

Lipoic acid in combination with a chelator ameliorates lead-induced peroxidative damages in rat kidney.

Archives of toxicology 20020801

Cofactors of mitochondrial enzymes attenuate copper-induced death in vitro and in vivo.

Annals of neurology 20020801

Cathepsin B responsiveness to glutathione and lipoic acid redox.

Antioxidants & redox signaling 20020801

Inhibition of glucose production and stimulation of bile flow by R (+)-alpha-lipoic acid enantiomer in rat liver.

Liver 20020801

Uptake, recycling, and antioxidant actions of alpha-lipoic acid in endothelial cells.

Free radical biology & medicine 20020701

Specific growth inhibition by acetate of an Escherichia coli strain expressing Era-dE, a dominant negative Era mutant.

Journal of molecular microbiology and biotechnology 20020701

Antioxidant and prooxidant activities of alpha-lipoic acid and dihydrolipoic acid.

Toxicology and applied pharmacology 20020701

Synthesis of a rabbit polyclonal antibody to the human sodium-dependent multivitamin transporter.

International journal for vitamin and nutrition research. Internationale Zeitschrift fur Vitamin- und Ernahrungsforschung. Journal international de vitaminologie et de nutrition 20020701

The toxicity of antioxidants and their metabolites.

Environmental toxicology and pharmacology 20020701

Lipoic acid increases glutathione production and enhances the effect of mercury in human cell lines.

Toxicology 20020614

Novel lipoic acid analogues that inhibit nitric oxide synthase.

Bioorganic & medicinal chemistry letters 20020603

Altered arachidonic acid biosynthesis and antioxidant protection mechanisms in Schwann cells grown in elevated glucose.

Journal of neurochemistry 20020601

[Autonomic neuropathy in diabetics, treatment possibilities].

Vnitrni lekarstvi 20020601

[Fatal Lepiota brunneoincarnata poisoning].

Anales de medicina interna (Madrid, Spain : 1984) 20020601

Effect of DL-alpha-lipoic acid on the status of lipid peroxidation and antioxidant enzymes in various brain regions of aged rats.

Experimental gerontology 20020601

The neuroprotective antioxidant alpha-lipoic acid induces detoxication enzymes in cultured astroglial cells.

Free radical research 20020601

Dihydrolipoic acid as an effective cofactor for peptide methionine sulfoxide reductase in enzymatic repair of oxidative damage to both lipid-free and lipid-bound apolipoprotein a-I.

Antioxidants & redox signaling 20020601

Solution structure and dynamics of the lipoic acid-bearing domain of human mitochondrial branched-chain alpha-keto acid dehydrogenase complex.

The Journal of biological chemistry 20020503

Arsenate reductase II. Purine nucleoside phosphorylase in the presence of dihydrolipoic acid is a route for reduction of arsenate to arsenite in mammalian systems.

Chemical research in toxicology 20020501

Burning mouth syndrome (BMS): double blind controlled study of alpha-lipoic acid (thioctic acid) therapy.

Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology 20020501

Antioxidant strategies for Alzheimer's disease.

The Proceedings of the Nutrition Society 20020501

The biosynthetic pathway for lipoic acid is present in plastids and mitochondria in Arabidopsis thaliana.

FEBS letters 20020424

Sustained ER Ca2+ depletion suppresses protein synthesis and induces activation-enhanced cell death in mast cells.

The Journal of biological chemistry 20020419

Kinetic and microcalorimetric analysis of substrate and cofactor interactions in epoxyalkane:CoM transferase, a zinc-dependent epoxidase.

Biochemistry 20020416

High-performance liquid chromatographic assay for alpha-lipoic acid and five of its metabolites in human plasma and urine.

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20020405

Synthesis of 1,2-dithiolane analogues of leucine for potential use in peptide chemistry.

Organic letters 20020404

Modulation of apoptosis and improved redox metabolism with the use of a new antioxidant formula.

Biochemical pharmacology 20020401

Delaying brain mitochondrial decay and aging with mitochondrial antioxidants and metabolites.

Annals of the New York Academy of Sciences 20020401

Mitochondrial decay in the aging rat heart: evidence for improvement by dietary supplementation with acetyl-L-carnitine and/or lipoic acid.

Annals of the New York Academy of Sciences 20020401

Can antioxidant diet supplementation protect against age-related mitochondrial damage?

Annals of the New York Academy of Sciences 20020401

Effect of alpha-lipoic acid on lipid peroxidation and anti-oxidant enzyme activities in diabetic rats.

Clinical and experimental pharmacology & physiology 20020401

Substrate channelling in 2-oxo acid dehydrogenase multienzyme complexes.

Biochemical Society transactions 20020401

Differential effects of short-chain fatty acids on head and neck squamous carcinoma cells.

The Laryngoscope 20020401

Characterization of the 5' regulatory region of the human sodium-dependent multivitamin transporter, hSMVT.

Biochimica et biophysica acta 20020319

Beneficial effects of alpha-lipoic acid plus vitamin E on neurological deficit, reactive gliosis and neuronal remodeling in the penumbra of the ischemic rat brain.

Neuroscience letters 20020315

Influence of controlled hypoxia and radical scavenging agents on erythropoietin and malondialdehyde concentrations in humans.

Acta physiologica Scandinavica 20020301

Protective effect of alpha-lipoic acid against ischaemic acute renal failure in rats.

Clinical and experimental pharmacology & physiology 20020301

Calcium oxalate stone disease: role of lipid peroxidation and antioxidants.

Urological research 20020301

Mitigation of free radical toxicity in hyperoxaluric condition by a novel derivative eicosapentaenoate-lipoate.

Human & experimental toxicology 20020301

Metabolic enzymes of mycobacteria linked to antioxidant defense by a thioredoxin-like protein.

Science (New York, N.Y.) 20020208

Dietary modulation of age-related changes in cerebral pro-oxidant status.

Neurochemistry international 20020201

Effect of increased concentration of D-glucose or L-fucose on monocyte adhesion to endothelial cell monolayers and activation of nuclear factor-kappaB.

Metabolism: clinical and experimental 20020201

Differential effects of the antioxidant alpha-lipoic acid on the proliferation of mitogen-stimulated peripheral blood lymphocytes and leukaemic T cells.

Molecular immunology 20020201

Thioredoxin-(dithiol-)linked inactivation of elastase.

Molecular immunology 20020201

Prevention of hypertension, insulin resistance, and oxidative stress by alpha-lipoic acid.

Hypertension (Dallas, Tex. : 1979) 20020201

Glucose-induced oxidative stress in mesangial cells.

Kidney international 20020201

Sulfur in human nutrition and applications in medicine.

Alternative medicine review : a journal of clinical therapeutic 20020201

Involvement of proteasome in endothelin-1 production in cultured vascular endothelial cells.

Japanese journal of pharmacology 20020201

Antimitochondrial antibodies in primary biliary cirrhosis: the role of xenobiotics.

Autoimmunity reviews 20020201

Biocytin and biotin uptake into NB2a neuroblastoma and C6 astrocytoma cells.

Brain research 20020125

R-alpha-lipoic acid action on cell redox status, the insulin receptor, and glucose uptake in 3T3-L1 adipocytes.

Archives of biochemistry and biophysics 20020115

Exploring the interest of 1,2-dithiolane ring system in peptide chemistry. Synthesis of a chemotactic tripeptide and x-ray crystal structure of a 4-amino-1,2-dithiolane-4-carboxylic acid derivative.

Bioorganic & medicinal chemistry 20020101

Effects of exercise training and antioxidant R-ALA on glucose transport in insulin-sensitive rat skeletal muscle.

Journal of applied physiology (Bethesda, Md. : 1985) 20020101

Peroxynitrite reaction with the reduced and the oxidized forms of lipoic acid: new insights into the reaction of peroxynitrite with thiols.

Archives of biochemistry and biophysics 20020101

Alpha-lipoic acid attenuates hyperglycemia and prevents glomerular mesangial matrix expansion in diabetes.

Journal of the American Society of Nephrology : JASN 20020101

Alpha-lipoic acid modulates NF-kappaB activity in human monocytic cells by direct interaction with DNA.

Experimental gerontology 20020101

Antioxidant supplementation decreases lipid peroxidation biomarker F(2)-isoprostanes in plasma of smokers.

Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 20020101

N-acetylcysteine augments adenovirus-mediated gene expression in human endothelial cells by enhancing transgene transcription and virus entry.

The journal of gene medicine 20020101

Lipoic acid increases glucose uptake by skeletal muscles of obese-diabetic ob/ob mice.

Diabetes, obesity & metabolism 20020101

Elimination of *O(2)(-)/H(2)O(2) by alpha-lipoic acid mediates the recovery of basal EDRF/NO availability and the reversal of superoxide dismutase-induced relaxation in diabetic rat aorta.

Diabetes, obesity & metabolism 20020101

Natural products used for diabetes.

Journal of the American Pharmaceutical Association (Washington,D.C. : 1996) 20020101

Activation of choline acetyl transferase by dihydrolipoic acid.

Molecular and cellular biochemistry 20020101

[Immunomodulating effect of berlithione in clean-up workers of the Chernobyl nuclear plant accident].

Likars'ka sprava 20020101

Pharmacokinetics, tolerability, and fructosamine-lowering effect of a novel, controlled-release formulation of alpha-lipoic acid.

Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists 20020101

[Complex evaluation of treatment efficacy in diabetic encephalopathy].

Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova 20020101

Myeloperoxidase-dependent caspase-3 activation and apoptosis in HL-60 cells: protection by the antioxidants ascorbate and (dihydro)lipoic acid.

Redox report : communications in free radical research 20020101

Phase II study of subcutaneously administered interleukin-2 in combination with medroxyprogesterone acetate and antioxidant agents as maintenance treatment in advanced cancer responders to previous chemotherapy.

Oncology reports 20020101

Oxidative stress in humans training in a cold, moderate altitude environment and their response to a phytochemical antioxidant supplement.

Wilderness & environmental medicine 20020101

[Biologic properties of lipoic acid].

Postepy higieny i medycyny doswiadczalnej 20020101

Oxidative stress and diabetic neuropathy: pathophysiological mechanisms and treatment perspectives.

Diabetes/metabolism research and reviews 20020101

Effects of protein kinase Cbeta inhibition on neurovascular dysfunction in diabetic rats: interaction with oxidative stress and essential fatty acid dysmetabolism.

Diabetes/metabolism research and reviews 20020101

Effects of alpha lipoic acid, ascorbic acid-6-palmitate, and fish oil on the glutathione, malonaldehyde, and fatty acids levels in erythrocytes of streptozotocin induced diabetic male rats.

Journal of cellular biochemistry 20020101

Lipoic acid and vitamin C potentiate nitric oxide synthesis in human aortic endothelial cells independently of cellular glutathione status.

Redox report : communications in free radical research 20020101

[New approaches to antioxidant therapy in multiple sclerosis].

Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova 20020101

Zinc availability from zinc lipoate and zinc sulfate in growing rats.

Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements (GMS) 20020101

Treatment of amatoxin poisoning: 20-year retrospective analysis.

Journal of toxicology. Clinical toxicology 20020101

Effects of certain micronutrients and melatonin on plasma lipid, lipid peroxidation, and homocysteine levels in rats.

Archives of medical research 20020101

Influence of lipoic acid on lipid metabolism and beta-adrenergic response to intravenous or oral administration of clenbuterol in broiler chickens.

Reproduction, nutrition, development 20020101

Covalent attachment of gold nanoparticles to DNA templates.

Journal of nanoscience and nanotechnology 20020101

Diabetic neuropathy--choices of treatment.

Romanian journal of internal medicine = Revue roumaine de medecine interne 20020101

Safety of long-term feeding of dl-alpha-lipoic acid and its effect on reduced glutathione:oxidized glutathione ratios in beagles.

Veterinary therapeutics : research in applied veterinary medicine 20020101

Effect of DL-alpha-lipoic acid on glutathione metabolic enzymes in aged rats.

Experimental gerontology 20011201

Measurement of the length of the a helical section of a peptide directly using atomic force microscopy.

Chemical & pharmaceutical bulletin 20011201

Two ways to stimulate glutathione.

Survival news (Atlanta, Ga.) 20011201

Carcinogenic and nephrotoxic alkaloids aristolochic acids upon activation by NADPH : cytochrome P450 reductase form adducts found in DNA of patients with Chinese herbs nephropathy.

General physiology and biophysics 20011201

Effect of DL-alpha-lipoic acid on mitochondrial enzymes in aged rats.

Chemico-biological interactions 20011128

Novel potent inhibitors of lipid peroxidation with protective effects against reperfusion arrhythmias.

Journal of medicinal chemistry 20011122

Sulfur-centered radical formation from the antioxidant dihydrolipoic acid.

The Journal of biological chemistry 20011116

Theoretical study of the conformation of the lipoamide arm in a mutant H protein.

Proteins 20011115

Restoration of glutathione levels in vascular smooth muscle cells exposed to high glucose conditions.

Free radical biology & medicine 20011115

Alpha-lipoic acid inhibits TNF-alpha-induced NF-kappaB activation and adhesion molecule expression in human aortic endothelial cells.

FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20011101

Anti-aging products, Part I. Can supplements rewind our body clocks?

Harvard women's health watch 20011101

Effect of selenolipoic acid on peroxynitrite-dependent inactivation of NADPH-cytochrome P450 reductase.

Free radical research 20011101

Energy, mood and behaviour: Part Two.

Nursing times 20011101

Lipoic acid improves survival in transgenic mouse models of Huntington's disease.

Neuroreport 20011029

Alpha-lipoic acid protects rat cortical neurons against cell death induced by amyloid and hydrogen peroxide through the Akt signalling pathway.

Neuroscience letters 20011026

Hypochlorous acid is a potent inhibitor of GST P1-1.

Chemico-biological interactions 20011025

A trail of research from lipoic acid to alpha-keto acid dehydrogenase complexes.

The Journal of biological chemistry 20011019

Advanced glycation endproducts change glutathione redox status in SH-SY5Y human neuroblastoma cells by a hydrogen peroxide dependent mechanism.

Neuroscience letters 20011012

Identification of an Arabidopsis cDNA encoding a lipoyltransferase located in plastids.

FEBS letters 20011012

Aqueous leaching properties and environmental implications of cadmium, lead and zinc trimercaptotriazine (TMT) compounds.

Water research 20011001

Enzymology of carbon-sulfur bond formation.

Current opinion in chemical biology 20011001

Use of antioxidant nutrients in the prevention and treatment of type 2 diabetes.

Journal of the American College of Nutrition 20011001

Molecular aspects of lipoic acid in the prevention of diabetes complications.

Nutrition (Burbank, Los Angeles County, Calif.) 20011001

Low molecular weight antioxidants and their role in skin ageing.

Clinical and experimental dermatology 20011001

Chronic fatigue syndrome: oxidative stress and dietary modifications.

Alternative medicine review : a journal of clinical therapeutic 20011001

Effects of thiol antioxidants on hepatocyte growth factor signaling in cardiac myocytes.

Antioxidants & redox signaling 20011001

Immunoreactivity of organic mimeotopes of the E2 component of pyruvate dehydrogenase: connecting xenobiotics with primary biliary cirrhosis.

Journal of immunology (Baltimore, Md. : 1950) 20010901

Versatile cytoprotective activity of lipoic acid may reflect its ability to activate signalling intermediates that trigger the heat-shock and phase II responses.

Medical hypotheses 20010901

alpha-Lipoic acid prevents the development of glucose-induced insulin resistance in 3T3-L1 adipocytes and accelerates the decline in immunoreactive insulin during cell incubation.

Metabolism: clinical and experimental 20010901

Solution structure of the lipoyl domain of the chimeric dihydrolipoyl dehydrogenase P64K from Neisseria meningitidis.

European journal of biochemistry 20010901

Antioxidants attenuate early up regulation of retinal vascular endothelial growth factor in streptozotocin-diabetic rats.

Diabetologia 20010901

Redirection of pyruvate catabolism in Lactococcus lactis by selection of mutants with additional growth requirements.

Applied microbiology and biotechnology 20010901

The therapeutic use of lipoic acid in diabetes: a current perspective.

Environmental toxicology and pharmacology 20010901

Purification, characterization, and cDNA cloning of lipoate-activating enzyme from bovine liver.

The Journal of biological chemistry 20010803

Effect of antioxidant treatment of streptozotocin-induced diabetic rats on endoneurial blood flow, motor nerve conduction velocity, and vascular reactivity of epineurial arterioles of the sciatic nerve.

Diabetes 20010801

The effects of treatment with alpha-lipoic acid or evening primrose oil on vascular hemostatic and lipid risk factors, blood flow, and peripheral nerve conduction in the streptozotocin-diabetic rat.

Metabolism: clinical and experimental 20010801

Cytochrome c oxidase partial deficiency-associated Leigh disease presenting as an extrapyramidal syndrome.

Journal of child neurology 20010801

Human enzymes involved in the metabolic activation of carcinogenic aristolochic acids: evidence for reductive activation by cytochromes P450 1A1 and 1A2.

Chemical research in toxicology 20010801

Amplification of antigen-antibody interactions based on biotin labeled protein-streptavidin network complex using impedance spectroscopy.

Biosensors & bioelectronics 20010801

[Detection and treatment of lower extremity neuropathy in patients with diabetic foot].

Klinichna khirurhiia 20010801

Effects of alpha-lipoic acid on deoxycorticosterone acetate-salt-induced hypertension in rats.

European journal of pharmacology 20010720

Interactions of exercise training and lipoic acid on skeletal muscle glucose transport in obese Zucker rats.

Journal of applied physiology (Bethesda, Md. : 1985) 20010701

Beneficial effects of alpha-lipoic acid and ascorbic acid on endothelium-dependent, nitric oxide-mediated vasodilation in diabetic patients: relation to parameters of oxidative stress.

Free radical biology & medicine 20010701

Effect of alpha-lipoic acid on vascular responses and nociception in diabetic rats.

Free radical biology & medicine 20010701

Evidence for reductive activation of carcinogenic aristolochic acids by prostaglandin H synthase -- (32)P-postlabeling analysis of DNA adduct formation.

Mutation research 20010627

Evidence for the extracellular reduction of alpha-lipoic acid by Leishmania donovani promastigotes: a transplasma membrane redox system.

Biochimica et biophysica acta 20010606

Effect of alpha-lipoic acid on the progression of endothelial cell damage and albuminuria in patients with diabetes mellitus: an exploratory study.

Diabetes research and clinical practice 20010601

New metabolic pathways of alpha-lipoic acid.

Drug metabolism and disposition: the biological fate of chemicals 20010601

The antihyperglycemic drug alpha-lipoic acid stimulates glucose uptake via both GLUT4 translocation and GLUT4 activation: potential role of p38 mitogen-activated protein kinase in GLUT4 activation.

Diabetes 20010601

Cytotoxicity of ascorbate, lipoic acid, and other antioxidants in hollow fibre in vitro tumours.

British journal of cancer 20010601

Do mammalian cells synthesize lipoic acid? Identification of a mouse cDNA encoding a lipoic acid synthase located in mitochondria.

FEBS letters 20010601

Electrocatalytic reduction of lipoic acid and electroenzymatic reduction of NAD(P)(+) for integrated dehydrogenase biosensors.

Biosensors & bioelectronics 20010601

Alpha-lipoic acid as a new treatment option for Alzheimer [corrected] type dementia.

Archives of gerontology and geriatrics 20010601

TNF-alpha dependent NF-kappa B activation in cultured canine keratinocytes is partly mediated by reactive oxygen species.

Veterinary dermatology 20010601

Lipoic acid metabolism in Arabidopsis thaliana: cloning and characterization of a cDNA encoding lipoyltransferase.

Plant & cell physiology 20010601

The isolation and characterisation of a Saccharomyces cerevisiae gene (LIP2) involved in the attachment of lipoic acid groups to mitochondrial enzymes.

FEMS microbiology letters 20010515

Protection by thiols of the mitochondrial complexes from 4-hydroxy-2-nonenal.

Free radical biology & medicine 20010501

Potential for creatine and other therapies targeting cellular energy dysfunction in neurological disorders.

Annals of neurology 20010501

Glutathione and alpha-lipoate in diabetic rats: nerve function, blood flow and oxidative state.

European journal of clinical investigation 20010501

Protein thiol oxidation by haloperidol results in inhibition of mitochondrial complex I in brain regions: comparison with atypical antipsychotics.

Neurochemistry international 20010401

Effects of vitamin E and alpha-lipoic acid on skeletal muscle contractile properties.

Journal of applied physiology (Bethesda, Md. : 1985) 20010401

Effects of an inhibitor of poly(ADP-ribose) polymerase, desmethylselegiline, trientine, and lipoic acid in transgenic ALS mice.

Experimental neurology 20010401

Efficacy of antioxidant therapies in transient focal ischemia in mice.

Stroke 20010401

Heterogeneous response of antimitochondrial autoantibodies and bile duct apical staining monoclonal antibodies to pyruvate dehydrogenase complex E2: the molecule versus the mimic.

Hepatology (Baltimore, Md.) 20010401

The glycine decarboxylase system: a fascinating complex.

Trends in plant science 20010401

Natural therapies for ocular disorders, part two: cataracts and glaucoma.

Alternative medicine review : a journal of clinical therapeutic 20010401

Oxidative stress participates in the breakdown of neuronal phenotype in experimental diabetic neuropathy.

Diabetologia 20010401

Schisandrin B modulates the ischemia-reperfusion induced changes in non-enzymatic antioxidant levels in isolated-perfused rat hearts.

Molecular and cellular biochemistry 20010401

Effects of vitamins and common drugs on reduction of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone in rat microsomes.

Archives of physiology and biochemistry 20010401

Inhibitory effect of alpha-lipoic acid and its positively charged amide analogue on nitric oxide production in RAW 264.7 macrophages.

Biochemical pharmacology 20010301

Oxidative stress in the aging rat heart is reversed by dietary supplementation with (R)-(alpha)-lipoic acid.

FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20010301

[Effect of alpha-lipoic acid on the apoptosis of PC12 cells induced by 6-hydroxydopamine].

Shi yan sheng wu xue bao 20010301

Antioxidant alpha-lipoic acid and protein turnover in insulin-resistant rat muscle.

Free radical biology & medicine 20010215

Reaction mechanism for mammalian pyruvate dehydrogenase using natural lipoyl domain substrates.

Archives of biochemistry and biophysics 20010215

Immunotherapy (recombinant interleukin 2), hormone therapy (medroxyprogesterone acetate) and antioxidant agents as combined maintenance treatment of responders to previous chemotherapy.

International journal of oncology 20010201

Protection against oxidative stress-induced insulin resistance in rat L6 muscle cells by mircomolar concentrations of alpha-lipoic acid.

Diabetes 20010201

Ataxia-telangiectasia: chronic activation of damage-responsive functions is reduced by alpha-lipoic acid.

Oncogene 20010118

Characterization of 16 novel human genes showing high similarity to yeast sequences.

Yeast (Chichester, England) 20010115

Effects of dietary supplementation of alpha-lipoic acid on early glomerular injury in diabetes mellitus.

Journal of the American Society of Nephrology : JASN 20010101

Thiols can either enhance or suppress DNA damage induction by catecholestrogens.

Free radical biology & medicine 20010101

The effect of gamma-linolenic acid-alpha-lipoic acid on functional deficits in the peripheral and central nervous system of streptozotocin-diabetic rats.

Journal of the neurological sciences 20010101

Biosynthesis of biotin and lipoic acid.

Vitamins and hormones 20010101

[Berlition R 300 oral -- alpha-lipoic acid preparation for the correction of body changes associated with high serum iron content].

Meditsina truda i promyshlennaia ekologiia 20010101

Activity of alpha-lipoic acid in the protection against oxidative stress in skin.

Current problems in dermatology 20010101

The antioxidant effect of DL-alpha-lipoic acid on copper-induced acute hepatitis in Long-Evans Cinnamon (LEC) rats.

Free radical research 20010101

Cataract development in diabetic sand rats treated with alpha-lipoic acid and its gamma-linolenic acid conjugate.

Diabetes/metabolism research and reviews 20010101

Acute mountain sickness; prophylactic benefits of antioxidant vitamin supplementation at high altitude.

High altitude medicine & biology 20010101

Diabetes-induced changes in retinal NAD-redox status: pharmacological modulation and implications for pathogenesis of diabetic retinopathy.

Pharmacology 20010101

Polymorphisms in the Mn-SOD and EC-SOD genes and their relationship to diabetic neuropathy in type 1 diabetes mellitus.

BMC medical genetics 20010101

Effects of age and dietary antioxidants on cerebral electron transport chain activity.

Neurobiology of aging 20010101

[Effect of alpha-lipoic acid preparations on bilirubin and transferrin levels and ferritin iron and transferrin iron content].

Ukrains'kyi biokhimichnyi zhurnal (1999 ) 20010101

Radical mechanisms of S-adenosylmethionine-dependent enzymes.

Advances in protein chemistry 20010101

PKA, PKC, and AKAP localization in and around the neuromuscular junction.

BMC neuroscience 20010101

Corpus cavernosum dysfunction in diabetic rats: effects of combined alpha-lipoic acid and gamma-linolenic acid treatment.

Diabetes/metabolism research and reviews 20010101

[Efficiency of thioctacid in dyscirculatory encephalopathy].

Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova 20010101

Neuronal death in the rat hippocampus in experimental diabetes and cerebral ischaemia treated with antioxidants.

Folia neuropathologica 20010101

Alpha-lipoic acid and alpha-lipoamide prevent oxidant-induced lysosomal rupture and apoptosis.

Redox report : communications in free radical research 20010101

Lipoic acid confers protection against oxidative injury in non-neuronal and neuronal tissue.

Nutritional neuroscience 20010101

Hypochlorous acid-modified low-density lipoprotein inactivates the lysosomal protease cathepsin B: protection by ascorbic and lipoic acids.

Redox report : communications in free radical research 20010101

Update on thiol status and supplements in physical exercise.

Canadian journal of applied physiology = Revue canadienne de physiologie appliquee 20010101

[Antioxidant and anti-AGE therapeutics: evaluation and perspectives].

Journal de la Societe de biologie 20010101

Electrochemical sensing for the determination of activated cyclic AMP-dependent protein kinase.

Analytical sciences : the international journal of the Japan Society for Analytical Chemistry 20010101

Attenuation of oxalate-induced nephrotoxicity by eicosapentaenoate-lipoate (EPA-LA) derivative in experimental rat model.

Prostaglandins, leukotrienes, and essential fatty acids 20010101

Escherichia coli LipA is a lipoyl synthase: in vitro biosynthesis of lipoylated pyruvate dehydrogenase complex from octanoyl-acyl carrier protein.

Biochemistry 20001212

Swinging arms and swinging domains in multifunctional enzymes: catalytic machines for multistep reactions.

Annual review of biochemistry 20000101

Anti-rheumatic compound aurothioglucose inhibits tumor necrosis factor-alpha-induced HIV-1 replication in latently infected OM10.1 and Ach2 cells.

International immunology 19990201

Cloning and functional expression of a cDNA encoding a mammalian sodium-dependent vitamin transporter mediating the uptake of pantothenate, biotin, and lipoate.

The Journal of biological chemistry 19980327

One-electron reduction of chromium(VI) by alpha-lipoic acid and related hydroxyl radical generation, dG hydroxylation and nuclear transcription factor-kappaB activation.

Archives of biochemistry and biophysics 19970215

Lipoic acid improves nerve blood flow, reduces oxidative stress, and improves distal nerve conduction in experimental diabetic neuropathy.

Diabetes care 19950801

The lipoic acid containing components of the 2-oxoacid dehydrogenase complexes mimic trifluoroacetylated proteins and are autoantigens associated with halothane hepatitis.

Chemical research in toxicology 19950101

Thiamine disulfide as a potent inhibitor of human immunodeficiency virus (type-1) production.

Biochemical and biophysical research communications 19941130

Identification of the dihydrolipoamide acetyltransferase subunit of the human pyruvate dehydrogenase complex as an autoantigen in halothane hepatitis. Molecular mimicry of trifluoroacetyl-lysine by lipoic acid.

European journal of biochemistry 19940801

Lipid peroxidation of erythrocyte membrane induced by lipoamide dehydrogenase in the presence of ADP-Fe3+.

Pharmacology & toxicology 19921001

Alpha-lipoic acid is an effective inhibitor of human immuno-deficiency virus (HIV-1) replication.

Klinische Wochenschrift 19911002

Thioredoxin fragment 31-36 is reduced by dihydrolipoamide and reduces oxidized protein.

Biochemical and biophysical research communications 19880115

Crystalline alpha-lipoic acid; a catalytic agent associated with pyruvate dehydrogenase.

Science (New York, N.Y.) 19510727

1200-22-2 | 1,2-Dithiolane-3-pentanoic acid, (3R)-

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