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Home > Fluorides > 119644-23-4
119644-23-4 | Uridine, 2',3'-dideoxy-3'-fluoro-5-iodo-
CAS No: 119644-23-4 Catalog No: AG000PDU MDL No:
Product Description
Catalog Number:
AG000PDU
Chemical Name:
Uridine, 2',3'-dideoxy-3'-fluoro-5-iodo-
CAS Number:
119644-23-4
Molecular Formula:
C9H10FIN2O4
Molecular Weight:
356.0896
IUPAC Name:
1-[(2R,4S,5R)-4-fluoro-5-(hydroxymethyl)oxolan-2-yl]-5-iodopyrimidine-2,4-dione
InChI:
InChI=1S/C9H10FIN2O4/c10-4-1-7(17-6(4)3-14)13-2-5(11)8(15)12-9(13)16/h2,4,6-7,14H,1,3H2,(H,12,15,16)/t4-,6+,7+/m0/s1
InChI Key:
FKHGYIRFPRYMOH-UBKIQSJTSA-N
SMILES:
OC[C@H]1O[C@H](C[C@@H]1F)n1cc(I)c(=O)[nH]c1=O
Properties
Complexity:
389
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
1
Defined Atom Stereocenter Count:
3
Defined Bond Stereocenter Count:
0
Exact Mass:
355.967g/mol
Formal Charge:
0
Heavy Atom Count:
17
Hydrogen Bond Acceptor Count:
5
Hydrogen Bond Donor Count:
2
Isotope Atom Count:
0
Molecular Weight:
356.092g/mol
Monoisotopic Mass:
355.967g/mol
Rotatable Bond Count:
2
Topological Polar Surface Area:
78.9A^2
Undefined Atom Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
XLogP3:
-0.5
Literature
| Title | Journal |
|---|---|
| Synthesis and in vitro antiviral activities of 3'-fluoro (or chloro) and 2',3'-difluoro 2',3'-dideoxynucleoside analogs against hepatitis B and C viruses. | Bioorganic & medicinal chemistry 20101101 |
| Bicyclic nucleoside inhibitors of varicella-zoster virus: synthesis and biological evaluation of 2',3'-dideoxy-3'-fluoro and 2'-deoxy-xylo derivatives. | Nucleosides, nucleotides & nucleic acids 20030101 |
| 3'-Fluoro-2',3'-dideoxy-5-chlorouridine: most selective anti-HIV-1 agent among a series of new 2'- and 3'-fluorinated 2',3'-dideoxynucleoside analogues. | Journal of medicinal chemistry 19890801 |
| 5-Halogeno-3'-fluoro-2',3'-dideoxyuridines as inhibitors of human immunodeficiency virus (HIV): potent and selective anti-HIV activity of 3'-fluoro-2',3'-dideoxy-5-chlorouridine. | Molecular pharmacology 19890501 |
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