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119567-79-2

119567-79-2 | 1H-1,2,4-Triazole-3-carboximidamide, 1-β-D-ribofuranosyl-

CAS No: 119567-79-2 Catalog No: AG0010OO MDL No:

Product Description

Catalog Number:
AG0010OO
Chemical Name:
1H-1,2,4-Triazole-3-carboximidamide, 1-β-D-ribofuranosyl-
CAS Number:
119567-79-2
Molecular Formula:
C8H13N5O4
Molecular Weight:
243.2199
IUPAC Name:
1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1,2,4-triazole-3-carboximidamide
InChI:
InChI=1S/C8H13N5O4/c9-6(10)7-11-2-13(12-7)8-5(16)4(15)3(1-14)17-8/h2-5,8,14-16H,1H2,(H3,9,10)/t3-,4-,5-,8-/m1/s1
InChI Key:
NHKZSTHOYNWEEZ-AFCXAGJDSA-N
SMILES:
OC[C@H]1O[C@H]([C@@H]([C@@H]1O)O)n1cnc(n1)C(=N)N
UNII:
R3B1994K2E

Properties

Complexity:
304  
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
4  
Defined Bond Stereocenter Count:
0
Exact Mass:
243.097g/mol
Formal Charge:
0
Heavy Atom Count:
17  
Hydrogen Bond Acceptor Count:
7  
Hydrogen Bond Donor Count:
5  
Isotope Atom Count:
0
Molecular Weight:
243.223g/mol
Monoisotopic Mass:
243.097g/mol
Rotatable Bond Count:
3  
Topological Polar Surface Area:
151A^2
Undefined Atom Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
XLogP3:
-1.8  

Literature

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Differences in clinical outcomes among hepatitis C genotype 1-infected patients treated with peginterferon alpha-2a or peginterferon alpha-2b plus ribavirin: a meta-analysis. Clinical and experimental gastroenterology 20120101
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Virologic response rates of weight-based taribavirin versus ribavirin in treatment-naive patients with genotype 1 chronic hepatitis C. Hepatology (Baltimore, Md.) 20101001
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Conformations of nucleoside analogue 1-(2'-deoxy-beta-D-ribofuranosyl)-1,2,4-triazole-3-carboxamide in different DNA sequence contexts. Biochemistry 20010213
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Treatment of lethal Pichinde virus infections in weanling LVG/Lak hamsters with ribavirin, ribamidine, selenazofurin, and ampligen. Antiviral research 19930101
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Synthesis and antiviral activity of 1,2,4-triazole-3-thiocarboxamide and 1,2,4-triazole-3-carboxamidine ribonucleosides. Journal of medicinal chemistry 19730801

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