200,000+ products from a single source!
sales@angenechem.com
1190-49-4 | L-Lysine, N6-(aminocarbonyl)-
CAS No: 1190-49-4 Catalog No: AG000P0D MDL No:MFCD00038143
Product Description
Catalog Number:
AG000P0D
Chemical Name:
L-Lysine, N6-(aminocarbonyl)-
CAS Number:
1190-49-4
Molecular Formula:
C7H15N3O3
Molecular Weight:
189.2123
MDL Number:
MFCD00038143
IUPAC Name:
(2S)-2-amino-6-(carbamoylamino)hexanoic acid
InChI:
InChI=1S/C7H15N3O3/c8-5(6(11)12)3-1-2-4-10-7(9)13/h5H,1-4,8H2,(H,11,12)(H3,9,10,13)/t5-/m0/s1
InChI Key:
XIGSAGMEBXLVJJ-YFKPBYRVSA-N
SMILES:
NC(=O)NCCCC[C@@H](C(=O)O)N
EC Number:
214-722-0
UNII:
133T7A0Y5K
Properties
Complexity:
184
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
1
Defined Atom Stereocenter Count:
1
Defined Bond Stereocenter Count:
0
Exact Mass:
189.111g/mol
Formal Charge:
0
Heavy Atom Count:
13
Hydrogen Bond Acceptor Count:
4
Hydrogen Bond Donor Count:
4
Isotope Atom Count:
0
Molecular Weight:
189.215g/mol
Monoisotopic Mass:
189.111g/mol
Rotatable Bond Count:
6
Topological Polar Surface Area:
118A^2
Undefined Atom Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
XLogP3:
-3.9
Literature
| Title | Journal |
|---|---|
| Simultaneous measurement of protein-bound 3-chlorotyrosine and homocitrulline by LC-MS/MS after hydrolysis assisted by microwave: application to the study of myeloperoxidase activity during hemodialysis. | Talanta 20120915 |
| Impact of carbamylation and glycation of collagen type I on migration of HT1080 human fibrosarcoma cells. | International journal of oncology 20120601 |
| Quantification of plasma homocitrulline using hydrophilic interaction liquid chromatography (HILIC) coupled to tandem mass spectrometry. | Analytical and bioanalytical chemistry 20120201 |
| Potential of Novel EPO Derivatives in Limb Ischemia. | Cardiology research and practice 20120101 |
| Impact of premature birth and critical illness on neonatal range of plasma amino acid concentrations determined by LC-MS/MS. | Molecular genetics and metabolism 20111201 |
| New device measures atmospheric isocyanic acid. | Environmental health perspectives 20110801 |
| Dual mechanism of brain damage induced in vivo by the major metabolites accumulating in hyperornithinemia-hyperammonemia-homocitrullinuria syndrome. | Brain research 20110119 |
| Myeloperoxidase-derived oxidation: mechanisms of biological damage and its prevention. | Journal of clinical biochemistry and nutrition 20110101 |
| Biological responses to perfluorododecanoic acid exposure in rat kidneys as determined by integrated proteomic and metabonomic studies. | PloS one 20110101 |
| Erythropoietin: recent developments in the treatment of spinal cord injury. | Neurology research international 20110101 |
| Anticitrulline antibodies can be caused by homocitrulline-containing proteins in rabbits. | Arthritis and rheumatism 20101101 |
| Carbamylation-dependent activation of T cells: a novel mechanism in the pathogenesis of autoimmune arthritis. | Journal of immunology (Baltimore, Md. : 1950) 20100615 |
| In vitro inhibition of low density lipoprotein carbamylation by vitamins, as an ameliorating atherosclerotic risk in uremic patients. | Scandinavian journal of clinical and laboratory investigation 20100401 |
| Evidence that the major metabolites accumulating in hyperornithinemia-hyperammonemia-homocitrullinuria syndrome induce oxidative stress in brain of young rats. | International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience 20091101 |
| Experimental evidence that ornithine and homocitrulline disrupt energy metabolism in brain of young rats. | Brain research 20090929 |
| Retinal degeneration. | Ophthalmology 20090801 |
| Identification of novel mutations in the SLC25A15 gene in hyperornithinemia-hyperammonemia-homocitrullinuria (HHH) syndrome: a clinical, molecular, and functional study. | Human mutation 20090501 |
| Phenotypic variability among patients with hyperornithinaemia-hyperammonaemia-homocitrullinuria syndrome homozygous for the delF188 mutation in SLC25A15. | Journal of medical genetics 20081101 |
| 'O', erythropoietin carbamoylation versus carbamylation. | Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20080901 |
| Hyperornithinemia-hyperammonemia-homocitrullinuria syndrome (HHH) presenting with acute fulminant hepatic failure. | Journal of pediatric gastroenterology and nutrition 20080301 |
| Hyperornithinemia-hyperammonemia-homocitrullinuria syndrome with stroke-like imaging presentation: clinical, biochemical and molecular analysis. | Journal of the neurological sciences 20080115 |
| Acetyl-lysine analog peptides as mechanistic probes of protein deacetylases. | The Journal of biological chemistry 20071221 |
| Protein carbamylation links inflammation, smoking, uremia and atherogenesis. | Nature medicine 20071001 |
| 'Multipurpose oxidase' in atherogenesis. | Nature medicine 20071001 |
| Determination of homocitrulline in urine of patients with HHH syndrome by liquid chromatography tandem mass spectrometry. | Analytical and bioanalytical chemistry 20061201 |
| HHH syndrome (hyperornithinaemia, hyperammonaemia, homocitrullinuria), with fulminant hepatitis-like presentation. | Journal of inherited metabolic disease 20060201 |
| Carbamylated low-density lipoprotein induces death of endothelial cells: a link to atherosclerosis in patients with kidney disease. | Kidney international 20050701 |
| Hyperornithinemia, hyperammonemia, and homocitrullinuria syndrome with evidence of mitochondrial dysfunction due to a novel SLC25A15 (ORNT1) gene mutation in a Palestinian family. | Journal of the neurological sciences 20040315 |
| The mitochondrial ornithine transporter. Bacterial expression, reconstitution, functional characterization, and tissue distribution of two human isoforms. | The Journal of biological chemistry 20030829 |
| Cloning and characterization of human ORNT2: a second mitochondrial ornithine transporter that can rescue a defective ORNT1 in patients with the hyperornithinemia-hyperammonemia-homocitrullinuria syndrome, a urea cycle disorder. | Molecular genetics and metabolism 20030801 |
| [Structure-function relationships of mitochondrial transporters]. | Nihon rinsho. Japanese journal of clinical medicine 20020401 |
| [Mitochondrial ornithine transporter deficiency]. | Nihon rinsho. Japanese journal of clinical medicine 20020401 |
| Seven novel mutations in the ORNT1 gene (SLC25A15) in patients with hyperornithinemia, hyperammonemia, and homocitrullinuria syndrome. | Human mutation 20011101 |
| Clinical and molecular findings in hyperornithinemia-hyperammonemia-homocitrullinuria syndrome. | Neurology 20010911 |
| HHH syndrome associated with callosal agenesis and disordered neuronal migration. | Developmental medicine and child neurology 20010601 |
| Carbamoylation of glomerular and tubular proteins in patients with kidney failure: a potential mechanism of ongoing renal damage. | Swiss medical weekly 20010324 |
| [Hyperornithinemia-hyperammonemia-homocitrullinuria syndrome]. | Ryoikibetsu shokogun shirizu 20010101 |
| Conscientious metabolic monitoring on a patient with hyperornithinemia-hyperammonemia-homocitrullinuria (HHH) syndrome undergoing anaesthesia. | Amino acids 20010101 |
Related Products
Featured Products
© 2019 Angene International Limited. All rights Reserved.