200,000+ products from a single source!

sales@angenechem.com

Home > Other Building Blocks > 1187-84-4

1187-84-4

1187-84-4 | H-Cys(Me)-OH

CAS No: 1187-84-4 Catalog No: AG003UA2 MDL No:MFCD00002612

Product Description

Catalog Number:
AG003UA2
Chemical Name:
H-Cys(Me)-OH
CAS Number:
1187-84-4
Molecular Formula:
C4H9NO2S
Molecular Weight:
135.1848
MDL Number:
MFCD00002612
IUPAC Name:
(2R)-2-amino-3-methylsulfanylpropanoic acid
InChI:
InChI=1S/C4H9NO2S/c1-8-2-3(5)4(6)7/h3H,2,5H2,1H3,(H,6,7)/t3-/m0/s1
InChI Key:
IDIDJDIHTAOVLG-VKHMYHEASA-N
SMILES:
CSC[C@@H](C(=O)O)N
UNII:
A34I1H07YM

Properties

Complexity:
86.1  
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
1  
Defined Bond Stereocenter Count:
0
Exact Mass:
135.035g/mol
Formal Charge:
0
Heavy Atom Count:
8  
Hydrogen Bond Acceptor Count:
4  
Hydrogen Bond Donor Count:
2  
Isotope Atom Count:
0
Molecular Weight:
135.181g/mol
Monoisotopic Mass:
135.035g/mol
Rotatable Bond Count:
3  
Topological Polar Surface Area:
88.6A^2
Undefined Atom Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
XLogP3:
-2.7  

Literature

Title Journal
Transcripts of sulphur metabolic genes are co-ordinately regulated in developing seeds of common bean lacking phaseolin and major lectins. Journal of experimental botany 20121001
TcyR regulates L-cystine uptake via the TcyABC transporter in Streptococcus mutans. FEMS microbiology letters 20120301
Crystal structures of two solute receptors for L-cystine and L-cysteine, respectively, of the human pathogen Neisseria gonorrhoeae. Journal of molecular biology 20120120
Metabolic profiling of the protozoan parasite Entamoeba invadens revealed activation of unpredicted pathway during encystation. PloS one 20120101
A functional phylogenomic view of the seed plants. PLoS genetics 20111201
Prebiotic synthesis of methionine and other sulfur-containing organic compounds on the primitive Earth: a contemporary reassessment based on an unpublished 1958 Stanley Miller experiment. Origins of life and evolution of the biosphere : the journal of the International Society for the Study of the Origin of Life 20110601
Synthesis of spirotetramates via a Diels-Alder approach. Organic letters 20110506
Measurement of S-methylcysteine and S-methyl-mercapturic acid in human urine by alkyl-chloroformate extractive derivatization and isotope-dilution gas chromatography-mass spectrometry. Biomedical chromatography : BMC 20110301
S-11C-methyl-L-cysteine: a new amino acid PET tracer for cancer imaging. Journal of nuclear medicine : official publication, Society of Nuclear Medicine 20110201
Drosophila models of Parkinson's disease: discovering relevant pathways and novel therapeutic strategies. Parkinson's disease 20110101
Analysis of common bean expressed sequence tags identifies sulfur metabolic pathways active in seed and sulfur-rich proteins highly expressed in the absence of phaseolin and major lectins. BMC genomics 20110101
Global analysis of gene expression in response to L-Cysteine deprivation in the anaerobic protozoan parasite Entamoeba histolytica. BMC genomics 20110101
Identification of Binding Mode of a Platinum (II) Complex, PtCl(2)(DIP), and Calf Thymus DNA. Bioinorganic chemistry and applications 20110101
Metabolome analysis revealed increase in S-methylcysteine and phosphatidylisopropanolamine synthesis upon L-cysteine deprivation in the anaerobic protozoan parasite Entamoeba histolytica. The Journal of biological chemistry 20101210
Rhodium-catalysed conjugate addition of arylboronic acids to enantiopure dehydroamino acid derivatives. Organic & biomolecular chemistry 20101121
Ligand substitution reactions and cytotoxic properties of [Au(L)Cl2](+) and [AuCl2(DMSO)2]+ complexes (L=ethylenediamine and S-methyl-l-cysteine). Journal of inorganic biochemistry 20100901
Drosophila melanogaster in the study of human neurodegeneration. CNS & neurological disorders drug targets 20100801
Global regulation of gene expression in response to cysteine availability in Clostridium perfringens. BMC microbiology 20100101
The effects of time-released garlic powder tablets on multifunctional cardiovascular risk in patients with coronary artery disease. Lipids in health and disease 20100101
Rhizobium leguminosarum bv. trifolii rosR is required for interaction with clover, biofilm formation and adaptation to the environment. BMC microbiology 20100101
TXNL6 is a novel oxidative stress-induced reducing system for methionine sulfoxide reductase a repair of α-crystallin and cytochrome C in the eye lens. PloS one 20100101
The cytotoxic effects of some selected gold(III) complexes on 4T1 cells and their role in the prevention of breast tumor growth in BALB/c mice. Journal of B.U.ON. : official journal of the Balkan Union of Oncology 20100101
No Modifying Effect of Antioxidant N-Acetyl-L-Cysteine on Fenofibrate-induced Hepatocarcinogenesis in Rats. Journal of toxicologic pathology 20091201
Methionine gamma-lyase: mechanistic deductions from the kinetic pH-effects. The role of the ionic state of a substrate in the enzymatic activity. Biochimica et biophysica acta 20091001
Phenylalanine 4-monooxygenase and the role of endobiotic metabolism enzymes in xenobiotic biotransformation. Expert opinion on drug metabolism & toxicology 20091001
Methionine, alpha-methylmethionine and S-methylcysteine radical cations: generations and dissociations in the gas phase. Physical chemistry chemical physics : PCCP 20090921
Influence of the chloride concentration on ligand substitution reactions of [Pt(SMC)Cl(2)] with biologically relevant nucleophiles. Dalton transactions (Cambridge, England : 2003) 20090621
Ecological genomics of Boechera stricta: identification of a QTL controlling the allocation of methionine- vs branched-chain amino acid-derived glucosinolates and levels of insect herbivory. Heredity 20090501
Methyl iodide-induced fetal hypothyroidism implicated in late-stage fetal death in rabbits. Inhalation toxicology 20090501
Two-day inhalation toxicity study of methyl iodide in the rat. Inhalation toxicology 20090501
Evaluation of respiratory parameters in rats and rabbits exposed to methyl iodide. Inhalation toxicology 20090501
Identification and molecular characterization of tryptophanase encoded by tnaA in Porphyromonas gingivalis. Microbiology (Reading, England) 20090301
Human phenylalanine monooxygenase and thioether metabolism. The Journal of pharmacy and pharmacology 20090101
Coordinations between gene modules control the operation of plant amino acid metabolic networks. BMC systems biology 20090101
Mouse recombinant phenylalanine monooxygenase and the S-oxygenation of thioether substrates. Journal of biochemical and molecular toxicology 20090101
Deletion of mouse MsrA results in HBO-induced cataract: MsrA repairs mitochondrial cytochrome c. Molecular vision 20090101
Equilibrium and kinetic investigations of the interaction of model platinum(II) complex with DNA constituents in reference to the antitumour activity: complex-formation reactions of [Pd(N,N-diethylethylenediamine)(H2O)2]2+ with ligands of biological significance and displacement reactions of DNA constituents. Bioinorganic chemistry and applications 20090101
Measurement of phenylalanine monooxygenase (PAH) activities. Current protocols in toxicology 20090101
Effects of cisplatin and other Pt(II) complexes on spontaneous motility of isolated human oviduct. Toxicology in vitro : an international journal published in association with BIBRA 20081201
Protection of vascular smooth muscle cells by over-expressed methionine sulphoxide reductase A: role of intracellular localization and substrate availability. Free radical research 20081101
Red Cabbage (Brassica oleracea) Ameliorates Diabetic Nephropathy in Rats. Evidence-based complementary and alternative medicine : eCAM 20080901
Seed storage protein deficiency improves sulfur amino acid content in common bean (Phaseolus vulgaris L.): redirection of sulfur from gamma-glutamyl-S-methyl-cysteine. Journal of agricultural and food chemistry 20080723
Complex-formation reactions of dicholoro(S-methyl-L-cysteine)palladium(II) with bio-relevant ligands. Labilization induced by S-donor chelates. Dalton transactions (Cambridge, England : 2003) 20080214
Influence of various combinations of mucolytic agent and non-ionic surfactant on intestinal absorption of poorly absorbed hydrophilic compounds. International journal of pharmaceutics 20080212
Bioactivation of selenocysteine derivatives by beta-lyases present in common gastrointestinal bacterial species. International journal for vitamin and nutrition research. Internationale Zeitschrift fur Vitamin- und Ernahrungsforschung. Journal international de vitaminologie et de nutrition 20080101
Methionine sulfoxide reductase A and a dietary supplement S-methyl-L-cysteine prevent Parkinson's-like symptoms. The Journal of neuroscience : the official journal of the Society for Neuroscience 20071121
Post-translational modifications in the active site region of methyl-coenzyme M reductase from methanogenic and methanotrophic archaea. The FEBS journal 20070901
Protective and alleviative effects from 4 cysteine-containing compounds on ethanol-induced acute liver injury through suppression of oxidation and inflammation. Journal of food science 20070901
Synthesis and biological evaluation of L-cysteine derivatives as mitotic kinesin Eg5 inhibitors. Bioorganic & medicinal chemistry letters 20070715
Antiinflammatory and antifibrogenic effects of s-ethyl cysteine and s-methyl cysteine in the kidney of diabetic mice. Molecular nutrition & food research 20070501
Synthesis, crystal structure, DNA binding and photo-induced DNA cleavage activity of (S-methyl-L-cysteine)copper(II) complexes of heterocyclic bases. Journal of inorganic biochemistry 20070201
Antioxidative and anti-inflammatory effects of four cysteine-containing agents in striatum of MPTP-treated mice. Nutrition (Burbank, Los Angeles County, Calif.) 20070101
N-acetylcysteine and S-methylcysteine inhibit MeIQx rat hepatocarcinogenesis in the post-initiation stage. Carcinogenesis 20060501
Function of domains of human O6-alkylguanine-DNA alkyltransferase. Biochemistry 20051122
TMAO and other organic osmolytes in the muscles of amphipods (Crustacea) from shallow and deep water of Lake Baikal. Comparative biochemistry and physiology. Part A, Molecular & integrative physiology 20050901
Re(CO)(3) complexes synthesized via an improved preparation of aqueous fac-[Re(CO)(3)(H(2)O)(3)](+) as an aid in assessing (99m)Tc imaging agents. Structural characterization and solution behavior of complexes with thioether-bearing amino acids as tridentate ligands. Inorganic chemistry 20050725
Versatile and stereoselective syntheses of orthogonally protected beta-methylcysteine and beta-methyllanthionine. Organic letters 20050623
Conserved protein TTHA1554 from Thermus thermophilus HB8 binds to glutamine synthetase and cystathionine beta-lyase. Biochimica et biophysica acta 20050615
Analysis of sulfur and selenium assimilation in Astragalus plants with varying capacities to accumulate selenium. The Plant journal : for cell and molecular biology 20050601
Vanadium(III) complexes with L-cysteine--stability, speciation and the effect on actin in hepatoma Morris 5123 cells. Journal of inorganic biochemistry 20041201
Kinetic mechanism of the serine acetyltransferase from Haemophilus influenzae. Archives of biochemistry and biophysics 20040915
S-methylcysteine may be a causal factor in monohalomethane neurotoxicity. Neurotoxicology 20040901
Effect of five cysteine-containing compounds on three lipogenic enzymes in Balb/cA mice consuming a high saturated fat diet. Lipids 20040901
Antioxidative and antiglycative effects of six organosulfur compounds in low-density lipoprotein and plasma. Journal of agricultural and food chemistry 20040602
Revised rat multi-organ carcinogenesis bioassay for whole-body detection of chemopreventive agents: modifying potential of S-methylcysteine. Cancer letters 20040331
Production of Se-methylselenocysteine in transgenic plants expressing selenocysteine methyltransferase. BMC plant biology 20040101
Garlic's ability to prevent in vitro Cu2+-induced lipoprotein oxidation in human serum is preserved in heated garlic: effect unrelated to Cu2+-chelation. Nutrition journal 20040101
Phenylalanine 4-monooxygenase and the S-oxidation of S-carboxymethyl-L-cysteine. Drug metabolism and drug interactions 20040101
Antioxidative activity of sulfur-containing compounds in Allium species for human low-density lipoprotein (LDL) oxidation in vitro. Journal of agricultural and food chemistry 20031119
Synthesis of orthogonally protected (R)- and (S)-2-methylcysteine via an enzymatic desymmeterization and Curtius rearrangement. The Journal of organic chemistry 20030627
Redox inversion of helicity in propeller-shaped molecules derived from s-methyl cysteine and methioninol. Organic letters 20030306
lcd from Streptococcus anginosus encodes a C-S lyase with alpha,beta-elimination activity that degrades L-cysteine. Microbiology (Reading, England) 20021201
Late confirmation of acute methyl bromide poisoning using S-methylcysteine adduct testing. Veterinary and human toxicology 20010801
Studies on a growth-inhibitory peptide derived from alpha-fetoprotein and some analogs. The journal of peptide research : official journal of the American Peptide Society 20010101
Studies on the methods for the determination of phosphorylation sites in highly phosphorylated peptides or proteins: phosphorylation sites of hen egg white riboflavin binding protein. Journal of biochemistry 19861101

© 2019 Angene International Limited. All rights Reserved.