CAS 118-00-3 | 2-Amino-1,9-dihydro-9-β-D-ribofuranosyl-6H-purin-6-one | CAS Number 118-00-3

Title	Journal
Design of nucleotide-mimetic and non-nucleotide inhibitors of the translation initiation factor eIF4E: Synthesis, structural and functional characterisation.	European journal of medicinal chemistry 20161129
Guanosine exerts neuroprotective effects by reversing mitochondrial dysfunction in a cellular model of Parkinson's disease.	International journal of molecular medicine 20141101
Simultaneous quantification of 12 different nucleotides and nucleosides released from renal epithelium and in human urine samples using ion-pair reversed-phase HPLC.	Purinergic signalling 20121201
The abasic site lesions in the human telomeric sequence d[TA(G(3)T(2)A)(3)G(3)]: a thermodynamic point of view.	Biochimica et biophysica acta 20121201
Synthesis and photophysical characterisation of a fluorescent nucleoside analogue that signals the presence of an abasic site in RNA.	Chembiochem : a European journal of chemical biology 20121105
Guanine nucleobase adducts formed by [Pt(di-(2-picolyl)amine)Cl]Cl: evidence that a tridentate ligand with only in-plane bulk can slow guanine base rotation.	Inorganic chemistry 20121105
Promotor polymorphisms of plasminogen activator inhibitor-1 and other thrombophilic genotypes in cerebral venous thrombosis: a case-control study in adults.	Journal of neurology 20121101
A new fluorometric assay for the study of DNA-binding and 3'-processing activities of retroviral integrases and its use for screening of HIV-1 integrase inhibitors.	Biochimie 20121101
Foxo3a targets mitochondria during guanosine 5'-triphosphate guided erythroid differentiation.	The international journal of biochemistry & cell biology 20121101
In vivo validation of DNA adduct formation by estragole in rats predicted by physiologically based biodynamic modelling.	Mutagenesis 20121101
Metabolite target analysis of human urine combined with pattern recognition techniques for the study of symptomatic gout.	Molecular bioSystems 20121101
Crystal structure analysis of the translation factor RF3 (release factor 3).	FEBS letters 20121019
tRNA processing by protein-only versus RNA-based RNase P: kinetic analysis reveals mechanistic differences.	Chembiochem : a European journal of chemical biology 20121015
Factors that influence the antiproliferative activity of half sandwich Ru(II)-[9]aneS3 coordination compounds: activation kinetics and interaction with guanine derivatives.	Dalton transactions (Cambridge, England : 2003) 20121014
Lead(II)-catalyzed oxidation of guanine in solution studied with electrospray ionization mass spectrometry.	The journal of physical chemistry. B 20121004
Nucleoside analogue electrochemical behaviour and in situ evaluation of DNA-clofarabine interaction.	Bioelectrochemistry (Amsterdam, Netherlands) 20121001
Effects of chronic guanosine treatment on hippocampal damage and cognitive impairment of rats submitted to chronic cerebral hypoperfusion.	Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology 20121001
Combining redox-proteomics and epigenomics to explain the involvement of oxidative stress in psychiatric disorders.	Molecular bioSystems 20121001
Guanosine produces an antidepressant-like effect through the modulation of NMDA receptors, nitric oxide-cGMP and PI3K/mTOR pathways.	Behavioural brain research 20121001
Identification and expression profiles of ADAR1 gene, responsible for RNA editing, in responses to dsRNA and GCRV challenge in grass carp (Ctenopharyngodon idella).	Fish & shellfish immunology 20121001
Eukaryotic initiation factor 5B: a new player for the anti-hepatitis C virus effect of ribavirin?	Medical hypotheses 20121001
In vivo and in vitro animal investigation of the effect of a mixture of herbal extracts from Tribulus terrestris and Cornus officinalis on penile erection.	The journal of sexual medicine 20121001
C8-linked bulky guanosine DNA adducts: experimental and computational insights into adduct conformational preferences and resulting mutagenicity.	Future medicinal chemistry 20121001
Filament formation of the FtsZ/tubulin-like protein TubZ from the Bacillus cereus pXO1 plasmid.	The Journal of biological chemistry 20120914
Benchmark studies on the building blocks of DNA. 2. Effect of biological environment on the electronic excitation spectrum of nucleobases.	The journal of physical chemistry. A 20120906
Oxidative damage of DNA, RNA and their metabolites in leukocytes, plasma and urine of Macaca mulatta: 8-oxoguanosine in urine is a useful marker for aging.	Free radical research 20120901
Sex differences in the Nociceptin/Orphanin FQ system in rat spinal cord following chronic morphine treatment.	Neuropharmacology 20120901
The mu opioid receptor modulates neurotransmission in the rat spinal ventral horn.	Anesthesia and analgesia 20120901
Sphingosine 1-phosphate receptor 2 antagonist JTE-013 increases the excitability of sensory neurons independently of the receptor.	Journal of neurophysiology 20120901
Cooperation of non-effective concentration of glutamatergic system modulators and antioxidant against oxidative stress induced by quinolinic acid.	Neurochemical research 20120901
Mycophenolate mofetil inhibits hepatitis C virus replication in human hepatic cells.	Virus research 20120901
Box H/ACA snoRNAs are preferred substrates for the trimethylguanosine synthase in the divergent unicellular eukaryote Trichomonas vaginalis.	RNA (New York, N.Y.) 20120901
Recognition of guanosine by dissimilar tRNA methyltransferases.	RNA (New York, N.Y.) 20120901
High genomic instability predicts survival in metastatic high-risk neuroblastoma.	Neoplasia (New York, N.Y.) 20120901
TLR13 recognizes bacterial 23S rRNA devoid of erythromycin resistance-forming modification.	Science (New York, N.Y.) 20120831
Characterization of heterotrimeric nucleotide-depleted Gα(i)-proteins by Bodipy-FL-GTPγS fluorescence anisotropy.	Archives of biochemistry and biophysics 20120815
RNA oxidation catalyzed by cytochrome c leads to its depurination and cross-linking, which may facilitate cytochrome c release from mitochondria.	Free radical biology & medicine 20120815
A new imidazolium-embedded C18 stationary phase with enhanced performance in reversed-phase liquid chromatography.	Analytica chimica acta 20120813
Thermodynamics of the GTP-GDP-operated conformational switch of selenocysteine-specific translation factor SelB.	The Journal of biological chemistry 20120810
Protective effects of guanosine against sepsis-induced damage in rat brain and cognitive impairment.	Brain, behavior, and immunity 20120801
An intravaginal ring for the simultaneous delivery of multiple drugs.	Journal of pharmaceutical sciences 20120801
Mitofusins and the mitochondrial permeability transition: the potential downside of mitochondrial fusion.	American journal of physiology. Heart and circulatory physiology 20120801
Activation of heme oxygenase and suppression of cGMP are associated with impaired endothelial function in obstructive sleep apnea with hypertension.	American journal of hypertension 20120801
Interaction of liposome-encapsulated cisplatin with biomolecules.	Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry 20120801
Guanosine protects human neuroblastoma SH-SY5Y cells against mitochondrial oxidative stress by inducing heme oxigenase-1 via PI3K/Akt/GSK-3β pathway.	Neurochemistry international 20120801
Synthesis and in vitro stability of nucleoside 5'-phosphonate derivatives.	European journal of medicinal chemistry 20120801
Intractable absence seizures in hyperinsulinism-hyperammonemia syndrome.	Pediatric neurology 20120801
Increased gene expression of the ABCC5 transporter without distinct changes in the expression of PDE5 in human cervical cancer cells during growth.	Anticancer research 20120801
Nascent-seq indicates widespread cotranscriptional RNA editing in Drosophila.	Molecular cell 20120713
Differential regulation by cyclic nucleotides of the CNGA4 and CNGB1b subunits in olfactory cyclic nucleotide-gated channels.	Science signaling 20120710
Solution structure of the N-terminal dsRBD of Drosophila ADAR and interaction studies with RNA.	Biochimie 20120701
Development of operational models of receptor activation including constitutive receptor activity and their use to determine the efficacy of the chemokine CCL17 at the CC chemokine receptor CCR4.	British journal of pharmacology 20120701
The histamine autoreceptor is a short isoform of the H₃ receptor.	British journal of pharmacology 20120701
Sar1 translocation onto the ER-membrane for vesicle budding has different pathways for promotion and suppression of ER-to-Golgi transport mediated through H89-sensitive kinase and ER-resident G protein.	Molecular and cellular biochemistry 20120701
Next-generation sequencing offers new insights into DNA degradation.	Trends in biotechnology 20120701
Stacked and continuous helical self-assemblies of guanosine monophosphates detected by vibrational circular dichroism.	Analytical and bioanalytical chemistry 20120701
Detection and typing of viruses using broadly sensitive cocktail-PCR and mass spectrometric cataloging: demonstration with dengue virus.	The Journal of molecular diagnostics : JMD 20120701
Retinal remodeling.	Japanese journal of ophthalmology 20120701
Estrogen receptor alpha modulates Toll-like receptor signaling in murine lupus.	Clinical immunology (Orlando, Fla.) 20120701
Structure of STING bound to cyclic di-GMP reveals the mechanism of cyclic dinucleotide recognition by the immune system.	Nature structural & molecular biology 20120701
Dose-dependent response of dendritic cells to 7-thia-8-oxo-guanosine and its modulation by polyinosinic:polycytidylic acid.	Experimental biology and medicine (Maywood, N.J.) 20120701
Identification of interaction partners of the dynamin-like protein DynA from Bacillus subtilis.	Communicative & integrative biology 20120701
Cyclic di-GMP sensing via the innate immune signaling protein STING.	Molecular cell 20120629
New quinoxaline derivatives as potential MT₁ and MT₂ receptor ligands.	Molecules (Basel, Switzerland) 20120625
Crystal structures of STING protein reveal basis for recognition of cyclic di-GMP.	Nature structural & molecular biology 20120624
Potential of the NBP method for the study of alkylation mechanisms: NBP as a DNA-model.	Chemical research in toxicology 20120618
Tax protein-induced expression of antiapoptotic Bfl-1 protein contributes to survival of human T-cell leukemia virus type 1 (HTLV-1)-infected T-cells.	The Journal of biological chemistry 20120615
Human MTH3 (NUDT18) protein hydrolyzes oxidized forms of guanosine and deoxyguanosine diphosphates: comparison with MTH1 and MTH2.	The Journal of biological chemistry 20120615
Matrix rigidity controls endothelial differentiation and morphogenesis of cardiac precursors.	Science signaling 20120605
Transcriptional profile of GTP-mediated differentiation of C2C12 skeletal muscle cells.	Purinergic signalling 20120601
Collection and storage of red blood cells with anticoagulant and additive solution with a physiologic pH.	Transfusion 20120601
The regulation of cardiac activity by nitric oxide (NO) in the Vietnamese stick insect, Baculum extradentatum.	Cellular signalling 20120601
Distinct pattern of oxidative DNA damage and DNA repair in follicular thyroid tumours.	Journal of molecular endocrinology 20120601
Novel role of NF-κB-p65 in antioxidant homeostasis in human kidney-2 cells.	American journal of physiology. Renal physiology 20120601
Computational insights into the inhibition of inosine 5'-monophosphate dehydrogenase by mycophenolic acid analogs: three-dimensional quantitative structure-activity relationship and molecular docking studies.	Chemical biology & drug design 20120601
Receptor conformations involved in dopamine D(2L) receptor functional selectivity induced by selected transmembrane-5 serine mutations.	Molecular pharmacology 20120601
Adenosine modification may be preferred for reducing siRNA immune stimulation.	Nucleic acid therapeutics 20120601
Deep EST profiling of developing fenugreek endosperm to investigate galactomannan biosynthesis and its regulation.	Plant molecular biology 20120601
Fluorometric detection of adenine in target DNA by exciplex formation with fluorescent 8-arylethynylated deoxyguanosine.	Bioorganic & medicinal chemistry letters 20120601
Exploring purine N7 interactions via atomic mutagenesis: the group I ribozyme as a case study.	RNA (New York, N.Y.) 20120601
A novel sulindac derivative that potently suppresses colon tumor cell growth by inhibiting cGMP phosphodiesterase and β-catenin transcriptional activity.	Cancer prevention research (Philadelphia, Pa.) 20120601
E2F1-dependent methyl cap formation requires RNA pol II phosphorylation.	Cell cycle (Georgetown, Tex.) 20120601
The circadian neuropeptide PDF signals preferentially through a specific adenylate cyclase isoform AC3 in M pacemakers of Drosophila.	PLoS biology 20120601
Two-step, one-pot synthesis of inosine, guanosine, and 2'-deoxyguanosine O6-ethers via intermediate O6-(benzotriazol-1-yl) derivatives.	Current protocols in nucleic acid chemistry 20120601
Bridging QTAIM with vibrational spectroscopy: the energy of intramolecular hydrogen bonds in DNA-related biomolecules.	Physical chemistry chemical physics : PCCP 20120528
Ionic liquids promote PCR amplification of DNA.	Chemical communications (Cambridge, England) 20120528
The DNA damage checkpoint protein ATM promotes hepatocellular apoptosis and fibrosis in a mouse model of non-alcoholic fatty liver disease.	Cell cycle (Georgetown, Tex.) 20120515
Signal transduction pathway activity compensates dopamine D₂/D₃ receptor density changes in Parkinson's disease: a preliminary comparative human brain receptor autoradiography study with [³H]raclopride and [³⁵S]GTPγS.	Brain research 20120509
Diffusion and birefringence of bioactive dyes in a supramolecular guanosine hydrogel.	Chemistry (Weinheim an der Bergstrasse, Germany) 20120507
Exploring light and life.	The Journal of biological chemistry 20120504
A-to-I editing of microRNAs: regulating the regulators?	Seminars in cell & developmental biology 20120501
Sensitivity to μ-opioid receptor-mediated anti-nociception is determined by cross-regulation between μ- and δ-opioid receptors at supraspinal level.	British journal of pharmacology 20120501
The intricate relationship between RNA structure, editing, and splicing.	Seminars in cell & developmental biology 20120501
Lysophosphatidylinositol stimulates [³⁵S]GTPγS binding in the rat prefrontal cortex and hippocampus.	Neurochemical research 20120501
Hydrostatic and osmotic pressure study of the RNA hydration.	Molecular biology reports 20120501
Acetylcholine-evoked afterdischarge in Aplysia bag cell neurons.	Journal of neurophysiology 20120501
Age-dependent increases in the oxidative damage of DNA, RNA, and their metabolites in normal and senescence-accelerated mice analyzed by LC-MS/MS: urinary 8-oxoguanosine as a novel biomarker of aging.	Free radical biology & medicine 20120501
Synthesis and biological evaluation of a series of thieno-expanded tricyclic purine 2'-deoxy nucleoside analogues.	Bioorganic & medicinal chemistry 20120501
Novel peptide for attenuation of hypoxia-induced pulmonary hypertension via modulation of nitric oxide release and phosphodiesterase -5 activity.	Peptides 20120501
Enzymatic synthesis of 8-vinyl- and 8-styryl-2'-deoxyguanosine modified DNA--novel fluorescent molecular probes.	Bioorganic & medicinal chemistry letters 20120501
Statistical parametric mapping reveals regional alterations in cannabinoid CB1 receptor distribution and G-protein activation in the 3D reconstructed epileptic rat brain.	Epilepsia 20120501
Supramolecular arrangement of guanosine/5-guanosine monophosphate binary mixtures studied by methods of circular dichroism.	Chirality 20120501
Structure and functional analysis of the RNA- and viral phosphoprotein-binding domain of respiratory syncytial virus M2-1 protein.	PLoS pathogens 20120501
Synthesis, binding affinity, and functional in vitro activity of 3-benzylaminomorphinan and 3-benzylaminomorphine ligands at opioid receptors.	Journal of medicinal chemistry 20120426
Signaling property study of adhesion G-protein-coupled receptors.	FEBS letters 20120424
β-arrestin2 regulates cannabinoid CB1 receptor signaling and adaptation in a central nervous system region-dependent manner.	Biological psychiatry 20120415
Structural basis for dual nucleotide selectivity of aminoglycoside 2''-phosphotransferase IVa provides insight on determinants of nucleotide specificity of aminoglycoside kinases.	The Journal of biological chemistry 20120413
Allosteric modulator ORG27569 induces CB1 cannabinoid receptor high affinity agonist binding state, receptor internalization, and Gi protein-independent ERK1/2 kinase activation.	The Journal of biological chemistry 20120406
Geissoschizine methyl ether, an alkaloid in Uncaria hook, is a potent serotonin ₁A receptor agonist and candidate for amelioration of aggressiveness and sociality by yokukansan.	Neuroscience 20120405
Assignments of backbone ¹H, ¹³C and ¹⁵N resonances in H-Ras (1-166) complexed with GppNHp at physiological pH.	Biomolecular NMR assignments 20120401
In vivo characterization of several rodent glioma models by 1H MRS.	NMR in biomedicine 20120401
DNA damage in lead-exposed hepatocytes: coexistence of apoptosis and necrosis?	Drug and chemical toxicology 20120401
Hormonal control of mammalian oocyte meiosis at diplotene stage.	Cellular and molecular life sciences : CMLS 20120401
Induction of apoptosis by type Iβ protein kinase G in the human breast cancer cell lines MCF-7 and MDA-MB-468.	Cell biochemistry and function 20120401
Selective recognition and separation of nucleosides using carboxymethyl-β-cyclodextrin functionalized hybrid magnetic nanoparticles.	Colloids and surfaces. B, Biointerfaces 20120401
Hydrogen gas ameliorates oxidative stress in early brain injury after subarachnoid hemorrhage in rats.	Critical care medicine 20120401
Probes for narcotic receptor mediated phenomena. 44. Synthesis of an N-substituted 4-hydroxy-5-(3-hydroxyphenyl)morphan with high affinity and selective μ-antagonist activity.	European journal of medicinal chemistry 20120401
Mechanism of substrate selection by a highly specific CRISPR endoribonuclease.	RNA (New York, N.Y.) 20120401
The synthesis of 2'-methylseleno adenosine and guanosine 5'-triphosphates.	Bioorganic & medicinal chemistry 20120401
Separation of nucleobases and their derivatives with organic-high ionic strength aqueous phase systems by spiral high-speed counter-current chromatography.	Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20120401
Loxoribine pretreatment reduces Salmonella Enteritidis organ invasion in 1-day-old chickens.	Poultry science 20120401
A RelA-dependent two-tiered regulated proteolysis cascade controls synthesis of a contact-dependent intercellular signal in Myxococcus xanthus.	Molecular microbiology 20120401
Exploiting structure similarity in refinement: automated NCS and target-structure restraints in BUSTER.	Acta crystallographica. Section D, Biological crystallography 20120401
Structural basis for type VI secretion effector recognition by a cognate immunity protein.	PLoS pathogens 20120401
The Caenorhabditis elegans HEN1 ortholog, HENN-1, methylates and stabilizes select subclasses of germline small RNAs.	PLoS genetics 20120401
First total synthesis of a naturally occurring iodinated 5'-deoxyxylofuranosyl marine nucleoside.	Marine drugs 20120401
[Dynamic accumulation of dry matter and active element in Pinellia ternata of Taizhou].	Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20120401
Effects of ginsenoside on pacemaker potentials of cultured interstitial cells of Cajal clusters from the small intestine of mice.	Molecules and cells 20120331
The structural basis of the kinetic mechanism of a gap-filling X-family DNA polymerase that binds Mg(2+)-dNTP before binding to DNA.	Journal of molecular biology 20120330
The butter flavorant, diacetyl, forms a covalent adduct with 2-deoxyguanosine, uncoils DNA, and leads to cell death.	Journal of agricultural and food chemistry 20120328
δ-opioid receptor function in the dorsal striatum plays a role in high levels of ethanol consumption in rats.	The Journal of neuroscience : the official journal of the Society for Neuroscience 20120328
2'-Azido RNA, a versatile tool for chemical biology: synthesis, X-ray structure, siRNA applications, click labeling.	ACS chemical biology 20120316
Preparation of methacrylate-based monolith for capillary hydrophilic interaction chromatography and its application in determination of nucleosides in urine.	Journal of chromatography. A 20120309
Biochemical characterization of ribosome assembly GTPase RbgA in Bacillus subtilis.	The Journal of biological chemistry 20120309
Properties of an LNA-modified ricin RNA aptamer.	Biochemical and biophysical research communications 20120302
The delta opioid receptor antagonist, SoRI-9409, decreases yohimbine stress-induced reinstatement of ethanol-seeking.	Addiction biology 20120301
YQA14: a novel dopamine D3 receptor antagonist that inhibits cocaine self-administration in rats and mice, but not in D3 receptor-knockout mice.	Addiction biology 20120301
Increased ethanol intake in prodynorphin knockout mice is associated to changes in opioid receptor function and dopamine transmission.	Addiction biology 20120301
Synthesis of novel Eu(III) luminescent probe based on 9- acridinecarboxylic acid skelton for sensing of ds-DNA.	Journal of fluorescence 20120301
Wild-type and feedback-resistant phosphoribosyl pyrophosphate synthetases from Bacillus amyloliquefaciens: purification, characterization, and application to increase purine nucleoside production.	Applied microbiology and biotechnology 20120301
[(35)S]GTPγS binding and opioid tolerance and efficacy in mouse spinal cord.	Pharmacology, biochemistry, and behavior 20120301
Characterization of COR627 and COR628, two novel positive allosteric modulators of the GABA(B) receptor.	The Journal of pharmacology and experimental therapeutics 20120301
Modulation of guanosine nucleotides biosynthetic pathways enhanced GDP-L-fucose production in recombinant Escherichia coli.	Applied microbiology and biotechnology 20120301
Epigenetic modifications in cardiovascular disease.	Basic research in cardiology 20120301
The earliest stage of cognitive impairment in transition from normal aging to Alzheimer disease is marked by prominent RNA oxidation in vulnerable neurons.	Journal of neuropathology and experimental neurology 20120301
Two-step efficient synthesis of 5-methyluridine via two thermostable nucleoside phosphorylase from Aeropyrum pernix.	Bioorganic & medicinal chemistry letters 20120301
A corrected space group for Sulfolobus sulfataricus 5'-deoxy-5'-methylthioadenosine phosphorylase II.	Acta crystallographica. Section D, Biological crystallography 20120301
Short ORF-dependent ribosome shunting operates in an RNA picorna-like virus and a DNA pararetrovirus that cause rice tungro disease.	PLoS pathogens 20120301
Two programmed cell death systems in Escherichia coli: an apoptotic-like death is inhibited by the mazEF-mediated death pathway.	PLoS biology 20120301
Quantitative Proteomics of Intracellular Campylobacter jejuni Reveals Metabolic Reprogramming.	PLoS pathogens 20120301
Statistical analysis of readthrough levels for nonsense mutations in mammalian cells reveals a major determinant of response to gentamicin.	PLoS genetics 20120301
B-type natriuretic Peptide assay for the diagnosis and prognosis of patent ductus arteriosus in preterm infants.	Korean circulation journal 20120301
Online extraction and isolation of highly polar chemical constituents from Brassica napus L. pollen by high shear technique coupled with high-performance counter-current chromatography.	Journal of separation science 20120301
Pharmacokinetics of mycophenolic acid and its phenyl glucuronide metabolite in kidney transplant recipients with renal impairment.	Archives of medical science : AMS 20120227
Aberrant cyclization affords a C-6 modified cyclic adenosine 5'-diphosphoribose analogue with biological activity in Jurkat T cells.	Journal of medicinal chemistry 20120223
Oxidation of the antiviral drug acyclovir and its biodegradation product carboxy-acyclovir with ozone: kinetics and identification of oxidation products.	Environmental science & technology 20120221
Selection of monoclonal antibodies against 6-oxo-M(1)dG and their use in an LC-MS/MS assay for the presence of 6-oxo-M(1)dG in vivo.	Chemical research in toxicology 20120220
Supramolecular dendrimers: convenient synthesis by programmed self-assembly and tunable thermoresponsivity.	Chemistry (Weinheim an der Bergstrasse, Germany) 20120220
Diversity of archaeosine synthesis in crenarchaeota.	ACS chemical biology 20120217
Biochemical identification of a hydroperoxide derivative of the free 8-oxo-7,8-dihydroguanine base.	Free radical biology & medicine 20120215
Base pairing at the abasic site in DNA duplexes and its application in adenosine aptasensors.	Chembiochem : a European journal of chemical biology 20120213
Ras-related GTPases Rap1 and RhoA collectively induce the phagocytosis of serum-opsonized zymosan particles in macrophages.	The Journal of biological chemistry 20120210
Short-RNA selective binding of oligonucleotides modified using adenosine and guanosine derivatives that possess cyclohexyl phosphates as substituents.	Organic & biomolecular chemistry 20120207
High constitutive activity is an intrinsic feature of ghrelin receptor protein: a study with a functional monomeric GHS-R1a receptor reconstituted in lipid discs.	The Journal of biological chemistry 20120203
A nucleotide phosphatase activity in the nucleotide binding domain of an orphan resistance protein from rice.	The Journal of biological chemistry 20120203
Oxidative damage to guanine nucleosides following combination chemotherapy with 5-fluorouracil and oxaliplatin.	Cancer chemotherapy and pharmacology 20120201
Nitric oxide synthase and cyclic GMP signaling in cardiac myocytes: from contractility to remodeling.	Journal of molecular and cellular cardiology 20120201
Chronic treatment with the opioid antagonist naltrexone favours the coupling of spinal cord μ-opioid receptors to Gαz protein subunits.	Neuropharmacology 20120201
3',4'-Dihydroxyflavonol reduces vascular contraction through Ca²⁺ desensitization in permeabilized rat mesenteric artery.	Naunyn-Schmiedeberg's archives of pharmacology 20120201
Formation and characterization of covalent guanosine adducts with electrochemistry-liquid chromatography-mass spectrometry.	Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20120201
The basic property of Lys385 is important for potentiation of the human α1 glycine receptor by ethanol.	The Journal of pharmacology and experimental therapeutics 20120201
3-Substituted pyrazole analogs of the cannabinoid type 1 (CB₁) receptor antagonist rimonabant: cannabinoid agonist-like effects in mice via non-CB₁, non-CB₂ mechanism.	The Journal of pharmacology and experimental therapeutics 20120201
Muscarinic receptor/G-protein coupling is reduced in the dorsomedial striatum of cognitively impaired aged rats.	Behavioural brain research 20120201
Mechanisms of systemic vasodilation by lysozyme-c in septic shock.	Journal of applied physiology (Bethesda, Md. : 1985) 20120201
Analyzing the metabolic stress response of recombinant Escherichia coli cultures expressing human interferon-beta in high cell density fed batch cultures using time course transcriptomic data.	Molecular bioSystems 20120201
Identification and characterization of mutations in the promoter region of the factor VIII gene.	Journal of thrombosis and haemostasis : JTH 20120201
Structures of NodZ α1,6-fucosyltransferase in complex with GDP and GDP-fucose.	Acta crystallographica. Section D, Biological crystallography 20120201
Chemical fingerprint analysis of Fritillaria delavayi Franch. by high-performance liquid chromatography.	Journal of separation science 20120201
An optimized electrochemistry-liquid chromatography-mass spectrometry method for studying guanosine oxidation.	Electrophoresis 20120201
Characterization of RNA damage under oxidative stress in Escherichia coli.	Biological chemistry 20120201
Functional promiscuity of the COG0720 family.	ACS chemical biology 20120120
Oligomer formation of the bacterial second messenger c-di-GMP: reaction rates and equilibrium constants indicate a monomeric state at physiological concentrations.	Journal of the American Chemical Society 20120118
The inverse agonist effect of rimonabant on G protein activation is not mediated by the cannabinoid CB1 receptor: evidence from postmortem human brain.	Biochemical pharmacology 20120115
Lung endothelial Ca2+ and permeability response to platelet-activating factor is mediated by acid sphingomyelinase and transient receptor potential classical 6.	American journal of respiratory and critical care medicine 20120115
R-Isovaline: a subtype-specific agonist at GABA(B)-receptors?	Neuroscience 20120110
Hydrogen sulfide as a cryogenic mediator of hypoxia-induced anapyrexia.	Neuroscience 20120110
Kinetic analysis of 3'-5' nucleotide addition catalyzed by eukaryotic tRNA(His) guanylyltransferase.	Biochemistry 20120110
In vitro selection and characterization of a novel Zn(II)-dependent phosphorothiolate thiolesterase ribozyme.	Biochemistry 20120110
The combination of organoselenium compounds and guanosine prevents glutamate-induced oxidative stress in different regions of rat brains.	Brain research 20120109
SK channel modulation rescues striatal plasticity and control over habit in cannabinoid tolerance.	Nature neuroscience 20120108
Enhancement of affinity in molecular recognition via hydrogen bonds by POSS-core dendrimer and its application for selective complex formation between guanosine triphosphate and 1,8-naphthyridine derivatives.	Organic & biomolecular chemistry 20120107
Incoherent feedforward control governs adaptation of activated ras in a eukaryotic chemotaxis pathway.	Science signaling 20120103
Erectogenic Effects of Clerodendron capitatum: Involvement of Phosphodiesterase Type-5 Inhibition.	Evidence-based complementary and alternative medicine : eCAM 20120101
Modulation of microRNA expression and function by ADARs.	Current topics in microbiology and immunology 20120101
Interdependency of cystathione γ-lyase and cystathione β-synthase in hydrogen sulfide-induced blood pressure regulation in rats.	American journal of hypertension 20120101
Toll-like receptor 7 ligands inhibit influenza A infection in chickens.	Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research 20120101
Evidence that hyperprolinemia alters glutamatergic homeostasis in rat brain: neuroprotector effect of guanosine.	Neurochemical research 20120101
GABAB receptor-positive modulators: brain region-dependent effects.	The Journal of pharmacology and experimental therapeutics 20120101
The relaxation effect and mechanism of action of higenamine in the rat corpus cavernosum.	International journal of impotence research 20120101
Protein Glycosylation in Aspergillus fumigatus Is Essential for Cell Wall Synthesis and Serves as a Promising Model of Multicellular Eukaryotic Development.	International journal of microbiology 20120101
Oxidative stress, mitochondrial dysfunction, and aging.	Journal of signal transduction 20120101
Probe dependence in the allosteric modulation of a G protein-coupled receptor: implications for detection and validation of allosteric ligand effects.	Molecular pharmacology 20120101
CEP-26401 (irdabisant), a potent and selective histamine H₃ receptor antagonist/inverse agonist with cognition-enhancing and wake-promoting activities.	The Journal of pharmacology and experimental therapeutics 20120101
Protection from myocardial ischemia/reperfusion injury by a positive allosteric modulator of the A₃ adenosine receptor.	The Journal of pharmacology and experimental therapeutics 20120101
Inhibition of Junin virus RNA synthesis by an antiviral acridone derivative.	Antiviral research 20120101
Oligodeoxynucleotides inhibit Toll-like receptor 3 mediated cytotoxicity and CXCL8 release in keratinocytes.	Experimental dermatology 20120101
Identification of the muscarinic pathway underlying cessation of sleep-related burst activity in rat thalamocortical relay neurons.	Pflugers Archiv : European journal of physiology 20120101
Asymmetry of 13C labeled 3-pyruvate affords improved site specific labeling of RNA for NMR spectroscopy.	Journal of biomolecular NMR 20120101
ppGpp inhibits peptide elongation cycle of chloroplast translation system in vitro.	Plant molecular biology 20120101
Genetics and Gene Expression Involving Stress and Distress Pathways in Fibromyalgia with and without Comorbid Chronic Fatigue Syndrome.	Pain research and treatment 20120101
A new proofreading mechanism for lesion bypass by DNA polymerase-λ.	EMBO reports 20120101
Blocking type I interferon production: a new therapeutic option to reduce the HIV-1-induced immune activation.	Clinical & developmental immunology 20120101
Advancements in Z-DNA: development of inducers and stabilizers for B to Z transition.	Current medicinal chemistry 20120101
A computational perspective of molecular interactions through virtual screening, pharmacokinetic and dynamic prediction on ribosome toxin A chain and inhibitors of Ricinus communis.	Pharmacognosy research 20120101
Effects of inhaled nitric oxide on hemostasis in healthy adults treated with heparin: a randomized, controlled, blinded crossover study.	Thrombosis journal 20120101
Posttranscriptional recoding by RNA editing.	Advances in protein chemistry and structural biology 20120101
Antisense sequencing improves the accuracy and precision of A-to-I editing measurements using the peak height ratio method.	BMC research notes 20120101
Tyrosine nitration of PA700 links proteasome activation to endothelial dysfunction in mouse models with cardiovascular risk factors.	PloS one 20120101
HIV-1 polymerase inhibition by nucleoside analogs: cellular- and kinetic parameters of efficacy, susceptibility and resistance selection.	PLoS computational biology 20120101
Platelet inhibition by nitrite is dependent on erythrocytes and deoxygenation.	PloS one 20120101
The ζ toxin induces a set of protective responses and dormancy.	PloS one 20120101
Differential treatment regimen-related effects of HU210 on CB(1) and D(2)-like receptor functionality in the rat basal ganglia.	Pharmacology 20120101
Non coding RNAs and viruses in the framework of the phylogeny of the genes, epigenesis and heredity.	International journal of molecular sciences 20120101
A case of persistent foot pain in a neurofibromatosis type I patient.	Case reports in medicine 20120101
Insertion site preference of Mu, Tn5, and Tn7 transposons.	Mobile DNA 20120101
Complexity of murine cardiomyocyte miRNA biogenesis, sequence variant expression and function.	PloS one 20120101
Chemical approaches for structure and function of RNA in postgenomic era.	Journal of nucleic acids 20120101
Cystinosin, MPDU1, SWEETs and KDELR belong to a well-defined protein family with putative function of cargo receptors involved in vesicle trafficking.	PloS one 20120101
Gene profile of myeloid-derived suppressive cells from the bone marrow of lysosomal acid lipase knock-out mice.	PloS one 20120101
NCAM180 regulates Ric8A membrane localization and potentiates β-adrenergic response.	PloS one 20120101
Active site mutations change the cleavage specificity of neprilysin.	PloS one 20120101
Specific Cooperation Between Imp-α2 and Imp-β/Ketel in Spindle Assembly During Drosophila Early Nuclear Divisions.	G3 (Bethesda, Md.) 20120101
Discovery of inhibitors of Leishmania β-1,2-mannosyltransferases using a click-chemistry-derived guanosine monophosphate library.	PloS one 20120101
On docking, scoring and assessing protein-DNA complexes in a rigid-body framework.	PloS one 20120101
CSF concentrations of cAMP and cGMP are lower in patients with Creutzfeldt-Jakob disease but not Parkinson's disease and amyotrophic lateral sclerosis.	PloS one 20120101
Epigenetic disregulation in oral cancer.	International journal of molecular sciences 20120101
Expression of Tas1 taste receptors in mammalian spermatozoa: functional role of Tas1r1 in regulating basal Ca²⁺ and cAMP concentrations in spermatozoa.	PloS one 20120101
Menopausal status modifies breast cancer risk associated with the myeloperoxidase (MPO) G463A polymorphism in Caucasian women: a meta-analysis.	PloS one 20120101
Suppression of ribosomal protein synthesis and protein translation factors by Peg-interferon alpha/ribavirin in HCV patients blood mononuclear cells (PBMC).	Journal of translational medicine 20120101
Direct Antioxidant Properties of Bilirubin and Biliverdin. Is there a Role for Biliverdin Reductase?	Frontiers in pharmacology 20120101
Reversal of cocaine-conditioned place preference through methyl supplementation in mice: altering global DNA methylation in the prefrontal cortex.	PloS one 20120101
Reversal of the ΔdegP phenotypes by a novel rpoE allele of Escherichia coli.	PloS one 20120101
Dynamic 5-HT2C receptor editing in a mouse model of obesity.	PloS one 20120101
Nebivolol: impact on cardiac and endothelial function and clinical utility.	Vascular health and risk management 20120101
Hesperetin, a Selective Phosphodiesterase 4 Inhibitor, Effectively Suppresses Ovalbumin-Induced Airway Hyperresponsiveness without Influencing Xylazine/Ketamine-Induced Anesthesia.	Evidence-based complementary and alternative medicine : eCAM 20120101
Comparison of the effects of adenosine, inosine, and their combination as an adjunct to reperfusion in the treatment of acute myocardial infarction.	ISRN cardiology 20120101
Tissue distribution and metabolism of guanosine in rats following intraperitoneal injection.	Journal of biological regulators and homeostatic agents 20120101
Identification of novel Mt-Guab2 inhibitor series active against M. tuberculosis.	PloS one 20120101
The protein partners of GTP cyclohydrolase I in rat organs.	PloS one 20120101
Temporal patterns of nucleotide misincorporations and DNA fragmentation in ancient DNA.	PloS one 20120101
Spironolactone lowers portal hypertension by inhibiting liver fibrosis, ROCK-2 activity and activating NO/PKG pathway in the bile-duct-ligated rat.	PloS one 20120101
Stimulators and activators of soluble guanylate cyclase: review and potential therapeutic indications.	Critical care research and practice 20120101
Silencing of amyloid precursor protein expression using a new engineered delta ribozyme.	International journal of Alzheimer's disease 20120101
Development of on-line high performance liquid chromatography (HPLC)-biochemical detection methods as tools in the identification of bioactives.	International journal of molecular sciences 20120101
The Immune Response to Trypanosoma cruzi: Role of Toll-Like Receptors and Perspectives for Vaccine Development.	Journal of parasitology research 20120101
Epigallocatechin-3-gallate has an anti-platelet effect in a cyclic AMP-dependent manner.	Journal of atherosclerosis and thrombosis 20120101
Spherical lactic acid bacteria activate plasmacytoid dendritic cells immunomodulatory function via TLR9-dependent crosstalk with myeloid dendritic cells.	PloS one 20120101
Functional characterization of EngA(MS), a P-loop GTPase of Mycobacterium smegmatis.	PloS one 20120101
Heme oxygenase-1 induction and organic nitrate therapy: beneficial effects on endothelial dysfunction, nitrate tolerance, and vascular oxidative stress.	International journal of hypertension 20120101
Gasotransmitters: novel regulators of epithelial na(+) transport?	Frontiers in physiology 20120101
Complexity of the Mycoplasma fermentans M64 genome and metabolic essentiality and diversity among mycoplasmas.	PloS one 20120101
The essential role of AMPA receptor GluR2 subunit RNA editing in the normal and diseased brain.	Frontiers in molecular neuroscience 20120101
Identification and characterization of two novel RNA editing sites in grin1b transcripts of embryonic Danio rerio.	Neural plasticity 20120101
Alternative Mechanisms to Initiate Translation in Eukaryotic mRNAs.	Comparative and functional genomics 20120101
A novel k-mer mixture logistic regression for methylation susceptibility modeling of CpG dinucleotides in human gene promoters.	BMC bioinformatics 20120101
Role of neural NO synthase (nNOS) uncoupling in the dysfunctional nitrergic vasorelaxation of penile arteries from insulin-resistant obese Zucker rats.	PloS one 20120101
Structure of an enzyme-derived phosphoprotein recognition domain.	PloS one 20120101
Whole cell biosynthesis of a functional oligosaccharide, 2'-fucosyllactose, using engineered Escherichia coli.	Microbial cell factories 20120101
Disrupting the Acyl Carrier Protein/SpoT interaction in vivo: identification of ACP residues involved in the interaction and consequence on growth.	PloS one 20120101
Risk factors for persistent pulmonary hypertension of the newborn.	Pulmonary circulation 20120101
Kaposi's Sarcoma-Associated Herpesvirus microRNAs.	Frontiers in microbiology 20120101
Comparative genomics reveals adaptation by Alteromonas sp. SN2 to marine tidal-flat conditions: cold tolerance and aromatic hydrocarbon metabolism.	PloS one 20120101
Down-regulation of GABA(A) receptor via promiscuity with the vasoactive peptide urotensin II receptor. Potential involvement in astrocyte plasticity.	PloS one 20120101
Type I interferons as ambiguous modulators of chronic inflammation in the central nervous system.	Frontiers in immunology 20120101
Time dependent neuroprotection of mycophenolate mofetil: effects on temporal dynamics in glial proliferation, apoptosis, and scar formation.	Journal of neuroinflammation 20120101
Regulation of the proteasome by AMPK in endothelial cells: the role of O-GlcNAc transferase (OGT).	PloS one 20120101
Endothelial dysfunction and diabetes: effects on angiogenesis, vascular remodeling, and wound healing.	International journal of vascular medicine 20120101
Electrochemical detection of individual single nucleotide polymorphisms using monobase-modified apoferritin-encapsulated nanoparticles.	Biosensors & bioelectronics 20120101
Low affinity GPCRs for metabolic intermediates: challenges for pharmacologists.	Frontiers in endocrinology 20120101
Hepatoprotective Effects of Panus giganteus (Berk.) Corner against Thioacetamide- (TAA-) Induced Liver Injury in Rats.	Evidence-based complementary and alternative medicine : eCAM 20120101
Back to basics: pitting edema and the optimization of hypertension treatment in incident peritoneal dialysis patients (BRAZPD).	PloS one 20120101
M. tuberculosis induces potent activation of IDO-1, but this is not essential for the immunological control of infection.	PloS one 20120101
NF-κB repression by PIAS3 mediated RelA SUMOylation.	PloS one 20120101
Chemical constituents and biological activities of the genus Subergorgia.	Pharmacognosy reviews 20120101
The evolving landscape of neurotoxicity by unconjugated bilirubin: role of glial cells and inflammation.	Frontiers in pharmacology 20120101
Targeting tumor perfusion and oxygenation to improve the outcome of anticancer therapy.	Frontiers in pharmacology 20120101
Pan-pathway based interaction profiling of FDA-approved nucleoside and nucleobase analogs with enzymes of the human nucleotide metabolism.	PloS one 20120101
Down-regulation of GEP100 causes increase in E-cadherin levels and inhibits pancreatic cancer cell invasion.	PloS one 20120101
Radiolabeled nucleosides for predicting and monitoring the cancer therapeutic efficacy of chemodrugs.	Current medicinal chemistry 20120101
Interplay between HIV-1 and Host Genetic Variation: A Snapshot into Its Impact on AIDS and Therapy Response.	Advances in virology 20120101
Studies on the restriction of murine leukemia viruses by mouse APOBEC3.	PloS one 20120101
Explicit hypoxia targeting with tumor suppression by creating an 'obligate' anaerobic Salmonella Typhimurium strain.	Scientific reports 20120101
Thrombospondin-1 in early flow-related remodeling of mesenteric arteries from young normotensive and spontaneously hypertensive rats.	The open cardiovascular medicine journal 20120101
The 3' splice site of influenza A segment 7 mRNA can exist in two conformations: a pseudoknot and a hairpin.	PloS one 20120101
The G protein coupled receptor 3 is involved in cAMP and cGMP signaling and maintenance of meiotic arrest in porcine oocytes.	PloS one 20120101
Evidence for a functional adrenomedullin signaling pathway in the mouse retina.	Molecular vision 20120101
Maternal diet modulates placenta growth and gene expression in a mouse model of diabetic pregnancy.	PloS one 20120101
Efficiency of purine utilization by Helicobacter pylori: roles for adenosine deaminase and a NupC homolog.	PloS one 20120101
Progression from Sustained BK Viruria to Sustained BK Viremia with Immunosuppression Reduction Is Not Associated with Changes in the Noncoding Control Region of the BK Virus Genome.	Journal of transplantation 20120101
Voltammetric investigation of DNA damage induced by nitrofurazone and short-lived nitro-radicals with the use of an electrochemical DNA biosensor.	Biosensors & bioelectronics 20120101
The Bin3 RNA methyltransferase targets 7SK RNA to control transcription and translation.	Wiley interdisciplinary reviews. RNA 20120101
Remyelination induced by a DNA aptamer in a mouse model of multiple sclerosis.	PloS one 20120101
Analysis of 5'-mononucleotides in infant formula and adult/pediatric nutritional formula by liquid chromatography: First Action 2011.20.	Journal of AOAC International 20120101
HILIC-MS/MS method for the quantitation of nucleotides in infant formula and adult nutritional formula: First Action 2011.21.	Journal of AOAC International 20120101
Presynaptic selectivity of a ligand for serotonin 1A receptors revealed by in vivo PET assays of rat brain.	PloS one 20120101
Associations between purine metabolites and clinical symptoms in schizophrenia.	PloS one 20120101
Targeting phosphodiesterases in anti-platelet therapy.	Handbook of experimental pharmacology 20120101
Quantitative and chemical fingerprint analysis for the quality evaluation of Isatis indigotica based on ultra-performance liquid chromatography with photodiode array detector combined with chemometric methods.	International journal of molecular sciences 20120101
Enzymatically active and inactive phosphodiesterases and diguanylate cyclases are involved in regulation of Motility or sessility in Escherichia coli CFT073.	mBio 20120101
2-Methylwyosine, a nucleoside with restricted anti conformation in the east region enforced by nucleobase moiety modification: synthesis and conformational analysis by NMR and molecular dynamics.	Nucleosides, nucleotides & nucleic acids 20120101
A possible explanation for anemia in patients treated with mycophenolic acid.	Transplantation 20111227
The differential modulation of USP activity by internal regulatory domains, interactors and eight ubiquitin chain types.	Chemistry & biology 20111223
Phosphorodiamidates as a promising new phosphate prodrug motif for antiviral drug discovery: application to anti-HCV agents.	Journal of medicinal chemistry 20111222
XPD and hOGG1 gene polymorphisms in reperfusion oxidative stress.	Genetics and molecular research : GMR 20111219
Development and in vitro characterization of a novel bifunctional μ-agonist/δ-antagonist opioid tetrapeptide.	ACS chemical biology 20111216
C(5) modified uracil derivatives showing antiproliferative and erythroid differentiation inducing activities on human chronic myelogenous leukemia K562 cells.	European journal of pharmacology 20111215
CCR2 receptor antagonists: optimization of biaryl sulfonamides to increase activity in whole blood.	Bioorganic & medicinal chemistry letters 20111215
Identifying guanosine self assembly at natural isotopic abundance by high-resolution 1H and 13C solid-state NMR spectroscopy.	Journal of the American Chemical Society 20111214
Pyruvate is the source of the two carbons that are required for formation of the imidazoline ring of 4-demethylwyosine.	Biochemistry 20111213
Discovery of aminobenzyloxyarylamides as κ opioid receptor selective antagonists: application to preclinical development of a κ opioid receptor antagonist receptor occupancy tracer.	Journal of medicinal chemistry 20111208
Involvement of NOX1/NADPH oxidase in morphine-induced analgesia and tolerance.	The Journal of neuroscience : the official journal of the Society for Neuroscience 20111207
DNA-catalyzed reductive amination.	Angewandte Chemie (International ed. in English) 20111202
Design, synthesis and characterisation of guanosine-based amphiphiles.	Chemistry (Weinheim an der Bergstrasse, Germany) 20111202
Role of gonadal hormones on mu-opioid-stimulated [³⁵S]GTPγS binding and morphine-mediated antinociception in male and female Sprague-Dawley rats.	Psychopharmacology 20111201
Effect of high pressure processing on the level of some purines and pyrimidines nucleosides and bases in dry cured and cooked ham.	Meat science 20111201
Possible biological markers of the time of processing of dry-cured ham.	Meat science 20111201
Conformational preferences of modified nucleoside N(2)-methylguanosine (m(2)G) and its derivative N(2), N(2)-dimethylguanosine (m(2)(2)G) occur at 26th position (hinge region) in tRNA.	Cell biochemistry and biophysics 20111201
Identification of the core sequence elements in Penaeus stylirostris densovirus promoters.	Virus genes 20111201
tRNA structural and functional changes induced by oxidative stress.	Cellular and molecular life sciences : CMLS 20111201
Effect of ΔFosB overexpression on opioid and cannabinoid receptor-mediated signaling in the nucleus accumbens.	Neuropharmacology 20111201
The 8-hydroxydeoxyguanosine concentrations according to hormone therapy and S326C polymorphism of OGG1 gene in postmenopausal women.	Molecular genetics and metabolism 20111201
Essential role for orbitofrontal serotonin 1B receptors in obsessive-compulsive disorder-like behavior and serotonin reuptake inhibitor response in mice.	Biological psychiatry 20111201
Urinary markers of nucleic acid oxidation and long-term mortality of newly diagnosed type 2 diabetic patients.	Diabetes care 20111201
Modulation of dADAR-dependent RNA editing by the Drosophila fragile X mental retardation protein.	Nature neuroscience 20111201
Asymmetry of (13)C labeled 3-pyruvate affords improved site specific labeling of RNA for NMR spectroscopy.	Journal of biomolecular NMR 20111201
Purine nucleoside phosphorylase deficiency: a mutation update.	Nucleosides, nucleotides & nucleic acids 20111201
Overexpression of dedicator of cytokinesis I (Dock180) in ovarian cancer correlated with aggressive phenotype and poor patient survival.	Histopathology 20111201
Glut1 deficiency syndrome and erythrocyte glucose uptake assay.	Annals of neurology 20111201
Dual or triple activation of TLR7, TLR8, and/or TLR9 by single-stranded oligoribonucleotides.	Nucleic acid therapeutics 20111201
The RNA silencing enzyme RNA polymerase v is required for plant immunity.	PLoS genetics 20111201
Treatment of myasthenia gravis based on its immunopathogenesis.	Journal of clinical neurology (Seoul, Korea) 20111201
Anti-adipogenic activity of Cordyceps militaris in 3T3-L1 cells.	Natural product communications 20111201
The Protective Effect of Black Ginseng Against Transient Focal Ischemia-induced Neuronal Damage in Rats.	The Korean journal of physiology & pharmacology : official journal of the Korean Physiological Society and the Korean Society of Pharmacology 20111201
Treatment of recalcitrant herpes simplex virus with topical imiquimod.	Cutis 20111201
[Study on HPLC fingerprint chromatograms of Arisaematis Rhizoma].	Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20111201
cGMP Signaling, Phosphodiesterases and Major Depressive Disorder.	Current neuropharmacology 20111201
A novel form of low-frequency hippocampal mossy fiber plasticity induced by bimodal mGlu1 receptor signaling.	The Journal of neuroscience : the official journal of the Society for Neuroscience 20111123
A metabolic profiling analysis of symptomatic gout in human serum and urine using high performance liquid chromatography-diode array detector technique.	Clinica chimica acta; international journal of clinical chemistry 20111120
RAM/Fam103a1 is required for mRNA cap methylation.	Molecular cell 20111118
An active-site guanine participates in glmS ribozyme catalysis in its protonated state.	Journal of the American Chemical Society 20111116
Solution structure of the state 1 conformer of GTP-bound H-Ras protein and distinct dynamic properties between the state 1 and state 2 conformers.	The Journal of biological chemistry 20111111
Synthesis of 2'-N-methylamino-2'-deoxyguanosine and 2'-N,N-dimethylamino-2'-deoxyguanosine and their incorporation into RNA by phosphoramidite chemistry.	The Journal of organic chemistry 20111104
Modulation of GABA transport by adenosine A1R-A2AR heteromers, which are coupled to both Gs- and G(i/o)-proteins.	The Journal of neuroscience : the official journal of the Society for Neuroscience 20111102
Sequential and opposing alterations of 5-HT(1A) receptor function during withdrawal from chronic morphine.	European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology 20111101
Retron Se72 utilizes a unique strategy of the self-priming initiation of reverse transcription.	Cellular and molecular life sciences : CMLS 20111101
Recombinant WNTs differentially activate β-catenin-dependent and -independent signalling in mouse microglia-like cells.	Acta physiologica (Oxford, England) 20111101
Protein therapy using heme-oxygenase-1 fused to a polyarginine transduction domain attenuates cerebral vasospasm after experimental subarachnoid hemorrhage.	Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 20111101
Transactivation of epidermal growth factor receptor by enhanced levels of endogenous angiotensin II contributes to the overexpression of Giα proteins in vascular smooth muscle cells from SHR.	Cellular signalling 20111101
Adenosine-to-inosine RNA editing meets cancer.	Carcinogenesis 20111101
The clozapine metabolite N-desmethylclozapine displays variable activity in diverse functional assays at human dopamine D₂ and serotonin 5-HT₁A receptors.	European journal of pharmacology 20111101
Sex difference in κ-opioid receptor (KOPR)-mediated behaviors, brain region KOPR level and KOPR-mediated guanosine 5'-O-(3-[35S]thiotriphosphate) binding in the guinea pig.	The Journal of pharmacology and experimental therapeutics 20111101
Differential effects of nociceptin/orphanin FQ (NOP) receptor agonists in acute versus chronic pain: studies with bifunctional NOP/μ receptor agonists in the sciatic nerve ligation chronic pain model in mice.	The Journal of pharmacology and experimental therapeutics 20111101
Pre-ovulatory LH/hCG surge decreases C-type natriuretic peptide secretion by ovarian granulosa cells to promote meiotic resumption of pre-ovulatory oocytes.	Human reproduction (Oxford, England) 20111101
Stability and mismatch discrimination of locked nucleic acid-DNA duplexes.	Biochemistry 20111101
A prophylactic effect of an oligodeoxynucleotide containing a cytidine-guanosine motif against Japanese cedar pollen-induced T-helper type 2 allergic response.	The Journal of asthma : official journal of the Association for the Care of Asthma 20111101
Evidence for macrocyclic lactone anthelmintic resistance in Dirofilaria immitis.	Topics in companion animal medicine 20111101
Simultaneous determination of five nucleosides and nucleobases of Rehmannia glutinosa Libosch. by high performance liquid chromatography.	Yao xue xue bao = Acta pharmaceutica Sinica 20111101
STING is a direct innate immune sensor of cyclic di-GMP.	Nature 20111027
8-(p-CF3-cinnamyl)-modified purine nucleosides as promising fluorescent probes.	Organic & biomolecular chemistry 20111026
Pin1 and WWP2 regulate GluR2 Q/R site RNA editing by ADAR2 with opposing effects.	The EMBO journal 20111019
Structural analysis of the Ras-like G protein MglA and its cognate GAP MglB and implications for bacterial polarity.	The EMBO journal 20111019
Towards multimodal HPLC separations on humic acid-bonded aminopropyl silica: RPLC and LEC behavior.	Talanta 20111015
GTP-dependent binding and nuclear transport of RNA polymerase II by Npa3 protein.	The Journal of biological chemistry 20111014
Protein glycoengineering enabled by the versatile synthesis of aminooxy glycans and the genetically encoded aldehyde tag.	Journal of the American Chemical Society 20111012
Structure-function analysis from the outside in: long-range tertiary contacts in RNA exhibit distinct catalytic roles.	Biochemistry 20111011
Molecular targeting of CSN5 in human hepatocellular carcinoma: a mechanism of therapeutic response.	Oncogene 20111006
Synthesis of 2'-deoxy-2'-[18F]fluoro-9-β-D-arabinofuranosylguanine: a novel agent for imaging T-cell activation with PET.	Molecular imaging and biology : MIB : the official publication of the Academy of Molecular Imaging 20111001
The state-of-the-art determination of urinary nucleosides using chromatographic techniques 'hyphenated' with advanced bioinformatic methods.	Analytical and bioanalytical chemistry 20111001
G-quadruplexes: from guanine gels to chemotherapeutics.	Molecular biotechnology 20111001
Guanosine supplementation reduces the antiproliferative and apoptotic effects of the IMPDH inhibitor gnidilatimonoein in K562 cells.	Cell biology international 20111001
Decitabine and suberoylanilide hydroxamic acid (SAHA) inhibit growth of ovarian cancer cell lines and xenografts while inducing expression of imprinted tumor suppressor genes, apoptosis, G2/M arrest, and autophagy.	Cancer 20111001
Anti-platelet therapy: phosphodiesterase inhibitors.	British journal of clinical pharmacology 20111001
Zinc homeostasis and signaling in health and diseases: Zinc signaling.	Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry 20111001
Potentiation of μ-opioid receptor-mediated signaling by ketamine.	Journal of neurochemistry 20111001
Regulation of ingestive behaviors in the rat by GSK1521498, a novel micro-opioid receptor-selective inverse agonist.	The Journal of pharmacology and experimental therapeutics 20111001
Physiological response to membrane protein overexpression in E. coli.	Molecular & cellular proteomics : MCP 20111001
Molecular determinants of PKA-dependent inhibition of TRPC5 channel.	American journal of physiology. Cell physiology 20111001
Triplet-state dynamics of a metalloporphyrin photosensitiser (PtTMPyP4) in the presence of halides and purine mononucleotides.	Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology 20111001
The G protein-coupled cannabinoid-1 (CB1) receptor of mammalian brain: inhibition by phthalate esters in vitro.	Neurochemistry international 20111001
Differential stringent control of Escherichia coli rRNA promoters: effects of ppGpp, DksA and the initiating nucleotides.	Microbiology (Reading, England) 20111001
Neutral loss and precursor ion scan tandem mass spectrometry for study of activated benzopyrene-DNA adducts.	Analytical and bioanalytical chemistry 20111001
Substrate-induced conformational changes in Plasmodium falciparum guanosine monophosphate synthetase.	The FEBS journal 20111001
CART peptide stimulation of G protein-mediated signaling in differentiated PC12 cells: identification of PACAP 6-38 as a CART receptor antagonist.	Neuropeptides 20111001
Pharmacological mechanisms underlying the antinociceptive and tolerance effects of the 6,14-bridged oripavine compound 030418.	Acta pharmacologica Sinica 20111001
Probing DNA interstrand cross-link formation by an oxidized abasic site using nonnative nucleotides.	Bioorganic & medicinal chemistry 20111001
The herpes simplex virus-1 transactivator infected cell protein-4 drives VEGF-A dependent neovascularization.	PLoS pathogens 20111001
Sustained CD8+ T cell memory inflation after infection with a single-cycle cytomegalovirus.	PLoS pathogens 20111001
Identification of widespread ultra-edited human RNAs.	PLoS genetics 20111001
Mycophenolic acid mediated mitochondrial membrane potential transition change lead to T lymphocyte apoptosis.	Journal of the Korean Surgical Society 20111001
Identification of the orphan G protein-coupled receptor GPR31 as a receptor for 12-(S)-hydroxyeicosatetraenoic acid.	The Journal of biological chemistry 20110930
A quantitative study of neuronal nitric oxide synthase expression in laminae I-III of the rat spinal dorsal horn.	Neuroscience 20110929
Identification of ML204, a novel potent antagonist that selectively modulates native TRPC4/C5 ion channels.	The Journal of biological chemistry 20110923
Alkylating potential of α,β-unsaturated compounds.	Organic & biomolecular chemistry 20110921
Circular dichroism and UV-Vis absorption spectroscopic monitoring of production of chiral silver nanoparticles templated by guanosine 5'-monophosphate.	The Analyst 20110921
A prebiotic role for 8-oxoguanosine as a flavin mimic in pyrimidine dimer photorepair.	Journal of the American Chemical Society 20110921
Nucleobase transport by human equilibrative nucleoside transporter 1 (hENT1).	The Journal of biological chemistry 20110916
Role for the membrane receptor guanylyl cyclase-C in attention deficiency and hyperactive behavior.	Science (New York, N.Y.) 20110916
Guanine-induced inhibition of renal Na(+)-ATPase activity: evidence for the involvement of the Gi protein-coupled receptor.	Archives of biochemistry and biophysics 20110915
Identification and quantification of nucleosides and nucleobases in Geosaurus and Leech by hydrophilic-interaction chromatography.	Talanta 20110915
Activation and inhibition of CTP synthase from Trypanosoma brucei, the causative agent of African sleeping sickness.	Bioorganic & medicinal chemistry letters 20110915
Ebola virus entry requires the cholesterol transporter Niemann-Pick C1.	Nature 20110915
Adjuvant effect of cationic liposomes and CpG depends on administration route.	Journal of controlled release : official journal of the Controlled Release Society 20110905
Effect of thioethers on DNA platination by trans-platinum complexes.	Inorganic chemistry 20110905
Administration route and carrier dependent effects on vaccine efficacy: implications for vaccine design.	Journal of controlled release : official journal of the Controlled Release Society 20110905
Identification of a novel Arabidopsis thaliana nitric oxide-binding molecule with guanylate cyclase activity in vitro.	FEBS letters 20110902
Genome-wide evaluation and discovery of vertebrate A-to-I RNA editing sites.	Biochemical and biophysical research communications 20110902
Nitric oxide signaling modulates synaptic transmission during early postnatal development.	Cerebral cortex (New York, N.Y. : 1991) 20110901
Dietary fish oil reduces DNA adduct formation while estradiol upregulates apoptosis in response to DNA damage in the rat colon.	Digestive diseases and sciences 20110901
Functional coupling between metabotropic glutamate receptors and G-proteins in rat cerebral cortex assessed by guanosine-5'-O-(3-[(35)S]thio)triphosphate binding assay.	Basic & clinical pharmacology & toxicology 20110901
Natriuretic peptide receptor-3 underpins the disparate regulation of endothelial and vascular smooth muscle cell proliferation by C-type natriuretic peptide.	British journal of pharmacology 20110901
ER-resident Gi2 protein controls sar1 translocation onto the ER during budding of transport vesicles.	Journal of cellular biochemistry 20110901
A dual acting compound releasing nitric oxide (NO) and ibuprofen, NCX 320, shows significant therapeutic effects in a mouse model of muscular dystrophy.	Pharmacological research 20110901
Characterization of a sphingosine 1-phosphate receptor antagonist prodrug.	The Journal of pharmacology and experimental therapeutics 20110901
Third intracellular loop of glucagon like-peptide-1 receptor is coupled with endogenous mono-ADP-ribosyltransferase - novel type of receptor regulation?	European journal of pharmacology 20110901
Estrogen regulation of the dopamine-activated GIRK channel in pituitary lactotrophs: implications for regulation of prolactin release during the estrous cycle.	American journal of physiology. Regulatory, integrative and comparative physiology 20110901
Neuroprotective effect of guanosine against glutamate-induced cell death in rat hippocampal slices is mediated by the phosphatidylinositol-3 kinase/Akt/ glycogen synthase kinase 3β pathway activation and inducible nitric oxide synthase inhibition.	Journal of neuroscience research 20110901
Validation of the catalytic mechanism of Escherichia coli purine nucleoside phosphorylase by structural and kinetic studies.	Biochimie 20110901
ppGpp in Sinorhizobium meliloti: biosynthesis in response to sudden nutritional downshifts and modulation of the transcriptome.	Molecular microbiology 20110901
Emerging drugs for varicella-zoster virus infections.	Expert opinion on emerging drugs 20110901
Mutagenicity of secondary oxidation products of 8-oxo-7,8-dihydro-2'-deoxyguanosine 5'-triphosphate (8-hydroxy-2'- deoxyguanosine 5'-triphosphate).	Mutation research 20110901
RIC8 is a guanine-nucleotide exchange factor for Galpha subunits that regulates growth and development in Neurospora crassa.	Genetics 20110901
Cyclic GMP induced apoptosis via protein kinase G in oestrogen receptor-positive and -negative breast cancer cell lines.	The FEBS journal 20110901
Signalling by the global regulatory molecule ppGpp in bacteria and chloroplasts of land plants.	Plant biology (Stuttgart, Germany) 20110901
Transfer RNA-mediated regulation of ribosome dynamics during protein synthesis.	Nature structural & molecular biology 20110901
6-Thioguanine inhibition of parathyroid hormone-related protein expression is mediated by GLI2.	Anticancer research 20110901
Influence of nitric oxide on in vitro growth, survival, steroidogenesis, and apoptosis of follicle stimulating hormone stimulated buffalo (Bubalus bubalis) preantral follicles.	Journal of veterinary science 20110901
BrabA.11339.a: anomalous diffraction and ligand binding guide towards the elucidation of the function of a 'putative β-lactamase-like protein' from Brucella melitensis.	Acta crystallographica. Section F, Structural biology and crystallization communications 20110901
Differences between Trypanosoma brucei gambiense groups 1 and 2 in their resistance to killing by trypanolytic factor 1.	PLoS neglected tropical diseases 20110901
[Effects of mycophenolic acid on human bone marrow-derived mesenchymal stem cells in vitro].	Zhejiang da xue xue bao. Yi xue ban = Journal of Zhejiang University. Medical sciences 20110901
Mechanisms and factors that influence high frequency retroviral recombination.	Viruses 20110901
Recombination in eukaryotic single stranded DNA viruses.	Viruses 20110901
Neuropsychiatric systemic lupus erythematosus.	Current neuropharmacology 20110901
Antioxidative caffeoylquinic acids and flavonoids from Hemerocallis fulva flowers.	Journal of agricultural and food chemistry 20110824
Stereoselective synthesis of amides sharing the guanosine 5'-monophosphate scaffold and Umami enhancement studies using human sensory and hT1R1/rT1R3 receptor assays.	Journal of agricultural and food chemistry 20110824
Synthesis and assembling properties of bioorganometallic cyclometalated Au(III) alkynyls bearing guanosine moieties.	Organic & biomolecular chemistry 20110821
Ligand modulation of the Epstein-Barr virus-induced seven-transmembrane receptor EBI2: identification of a potent and efficacious inverse agonist.	The Journal of biological chemistry 20110819
Systemic administration of guanosine promotes functional and histological improvement following an ischemic stroke in rats.	Brain research 20110817
Chronic neuropathic pain in mice reduces μ-opioid receptor-mediated G-protein activity in the thalamus.	Brain research 20110811
shRNA knockdown of guanylate cyclase 2e or cyclic nucleotide gated channel alpha 1 increases photoreceptor survival in a cGMP phosphodiesterase mouse model of retinitis pigmentosa.	Journal of cellular and molecular medicine 20110801
Progesterone signals through membrane progesterone receptors (mPRs) in MDA-MB-468 and mPR-transfected MDA-MB-231 breast cancer cells which lack full-length and N-terminally truncated isoforms of the nuclear progesterone receptor.	Steroids 20110801
Absolute configurations and stability of cyclic guanosine mono-adducts with glyoxal and methylglyoxal.	Chirality 20110801
Internalization of exogenous ADP-ribosylation factor 6 (Arf6) proteins into cells.	Molecular and cellular biochemistry 20110801
Curcumin mediates both dilation and constriction of peripheral arterioles via adrenergic receptors.	The Journal of investigative dermatology 20110801
Agonist-induced desensitization/resensitization of human G protein-coupled receptor 17: a functional cross-talk between purinergic and cysteinyl-leukotriene ligands.	The Journal of pharmacology and experimental therapeutics 20110801
Enhanced production of GDP-L-fucose by overexpression of NADPH regenerator in recombinant Escherichia coli.	Applied microbiology and biotechnology 20110801
Understanding the effect of different assay formats on agonist parameters: a study using the µ-opioid receptor.	Journal of biomolecular screening 20110801
High-throughput fluorescence polarization assay for the enzymatic activity of GTPase-activating protein of ADP-ribosylation factor (ARFGAP).	Journal of biomolecular screening 20110801
Depletion of GTP pool is not the predominant mechanism by which ribavirin exerts its antiviral effect on Lassa virus.	Antiviral research 20110801
Site-specific recognition of guanosine by manganese(III) corroles in DNA non-duplex regions through active oxygen transfer.	Chemistry (Weinheim an der Bergstrasse, Germany) 20110801
Sensitization to MDMA locomotor effects and changes in the functionality of 5-HT(2A) and D₂ receptors in mice.	Behavioural pharmacology 20110801
Quantification of cAMP and cGMP analogs in intact cells: pitfalls in enzyme immunoassays for cyclic nucleotides.	Naunyn-Schmiedeberg's archives of pharmacology 20110801
Enzyme kinetics of the mitochondrial deoxyribonucleoside salvage pathway are not sufficient to support rapid mtDNA replication.	PLoS computational biology 20110801
Epigenetic abnormalities in myeloproliferative neoplasms: a target for novel therapeutic strategies.	Clinical epigenetics 20110801
Benchmarking AMBER force fields for RNA: comparisons to NMR spectra for single-stranded r(GACC) are improved by revised χ torsions.	The journal of physical chemistry. B 20110728
Cell-type-specific CCK2 receptor signaling underlies the cholecystokinin-mediated selective excitation of hippocampal parvalbumin-positive fast-spiking basket cells.	The Journal of neuroscience : the official journal of the Society for Neuroscience 20110727
Conformational states of ADP ribosylation factor 1 complexed with different guanosine triphosphates as studied by 31P NMR spectroscopy.	Biochemistry 20110726
Hydrogen-bond-directed giant unilamellar vesicles of guanosine derivative: preparation, properties, and fusion.	Langmuir : the ACS journal of surfaces and colloids 20110719
The clinical potential of the acyclic (and cyclic) nucleoside phosphonates: the magic of the phosphonate bond.	Biochemical pharmacology 20110715
Activation of κ opioid receptors increases intrinsic excitability of dentate gyrus granule cells.	The Journal of physiology 20110715
The melatonergic agonist and clinically active antidepressant, agomelatine, is a neutral antagonist at 5-HT(2C) receptors.	The international journal of neuropsychopharmacology 20110701
Influence of irradiation on in vitro red-blood-cell (RBC) storage variables of leucoreduced RBCs in additive solution PAGGS-M.	Vox sanguinis 20110701
cGMP-dependent ABA-induced stomatal closure in the ABA-insensitive Arabidopsis mutant abi1-1.	The New phytologist 20110701
Measuring thermodynamic details of DNA hybridization using fluorescence.	Biopolymers 20110701
Role of SRC family kinase in extracellular renal cyclic guanosine 3',5'-monophosphate- and pressure-induced natriuresis.	Hypertension (Dallas, Tex. : 1979) 20110701
A three-dimensional pharmacophore model for IMPDH inhibitors.	Chemical biology & drug design 20110701
Multiple roles for Plasmodium berghei phosphoinositide-specific phospholipase C in regulating gametocyte activation and differentiation.	Cellular microbiology 20110701
The bulky N6 substituent of cabergoline is responsible for agonism of this drug at 5-hydroxytryptamine 5-HT2A and 5-HT2B receptors and thus is a determinant of valvular heart disease.	The Journal of pharmacology and experimental therapeutics 20110701
A selective adenosine sensor derived from a triplex DNA aptamer.	Analytical and bioanalytical chemistry 20110701
The L-kynurenine signalling pathway in trigeminal pain processing: a potential therapeutic target in migraine?	Cephalalgia : an international journal of headache 20110701
Arabidopsis thaliana nucleosidase mutants provide new insights into nucleoside degradation.	The New phytologist 20110701
Study of retention behaviour and mass spectrometry compatibility in zwitterionic hydrophilic interaction chromatography for the separation of modified nucleosides and nucleobases.	Journal of chromatography. A 20110701
Oxidative damage in multiple sclerosis lesions.	Brain : a journal of neurology 20110701
Paradoxical facilitation of exocytosis by inhibition of L-type calcium channels of bovine chromaffin cells.	Biochemical and biophysical research communications 20110701
Synaptic transmission from horizontal cells to cones is impaired by loss of connexin hemichannels.	PLoS biology 20110701
Complete genome sequence of Treponema succinifaciens type strain (6091).	Standards in genomic sciences 20110701
[Characterization of the Rela/SpoT homologue slr1325 (syn-rsh) of the cyanobacterium Synechocystis sp. PCC6803].	Wei sheng wu xue bao = Acta microbiologica Sinica 20110701
Selective activation of Akt1 by mammalian target of rapamycin complex 2 regulates cancer cell migration, invasion, and metastasis.	Oncogene 20110630
Nucleobase and ribose modifications control immunostimulation by a microRNA-122-mimetic RNA.	Journal of the American Chemical Society 20110622
The design and use of a simple System Suitability Test Mix for generic reverse phase high performance liquid chromatography-mass spectrometry systems and the implications for automated system monitoring using global software tracking.	Journal of chromatography. A 20110610
Calpain chronicle--an enzyme family under multidisciplinary characterization.	Proceedings of the Japan Academy. Series B, Physical and biological sciences 20110610
Metabolomic analysis characterizes tissue specific indomethacin-induced metabolic perturbations of rats.	The Analyst 20110607
Evidence for the existence of a specific g protein-coupled receptor activated by guanosine.	ChemMedChem 20110606
Ric-8B is a GTP-dependent G protein alphas guanine nucleotide exchange factor.	The Journal of biological chemistry 20110603
Guanosine is neuroprotective against oxygen/glucose deprivation in hippocampal slices via large conductance Ca²+-activated K+ channels, phosphatidilinositol-3 kinase/protein kinase B pathway activation and glutamate uptake.	Neuroscience 20110602
Protein cysteine S-guanylation and electrophilic signal transduction by endogenous nitro-nucleotides.	Amino acids 20110601
Quantification of hormone sensitive lipase phosphorylation and colocalization with lipid droplets in murine 3T3L1 and human subcutaneous adipocytes via automated digital microscopy and high-content analysis.	Assay and drug development technologies 20110601
Contribution of Rho-kinase to membrane excitability of murine colonic smooth muscle.	British journal of pharmacology 20110601
Synthesis of GDP-mannose using coupling fermentation of recombinant Escherichia coli.	Biotechnology letters 20110601
Genetic ablation of delta opioid receptors in nociceptive sensory neurons increases chronic pain and abolishes opioid analgesia.	Pain 20110601
Genetic and environmental influences on oxidative damage assessed in elderly Danish twins.	Free radical biology & medicine 20110601

Guanine nucleobase adducts formed by [Pt(di-(2-picolyl)amine)Cl]Cl: evidence that a tridentate ligand with only in-plane bulk can slow guanine base rotation.

Inorganic chemistry 20121105

Promotor polymorphisms of plasminogen activator inhibitor-1 and other thrombophilic genotypes in cerebral venous thrombosis: a case-control study in adults.

Journal of neurology 20121101

A new fluorometric assay for the study of DNA-binding and 3'-processing activities of retroviral integrases and its use for screening of HIV-1 integrase inhibitors.

Biochimie 20121101

Foxo3a targets mitochondria during guanosine 5'-triphosphate guided erythroid differentiation.

The international journal of biochemistry & cell biology 20121101

In vivo validation of DNA adduct formation by estragole in rats predicted by physiologically based biodynamic modelling.

Mutagenesis 20121101

Metabolite target analysis of human urine combined with pattern recognition techniques for the study of symptomatic gout.

Molecular bioSystems 20121101

Crystal structure analysis of the translation factor RF3 (release factor 3).

FEBS letters 20121019

tRNA processing by protein-only versus RNA-based RNase P: kinetic analysis reveals mechanistic differences.

Chembiochem : a European journal of chemical biology 20121015

Factors that influence the antiproliferative activity of half sandwich Ru(II)-[9]aneS3 coordination compounds: activation kinetics and interaction with guanine derivatives.

Dalton transactions (Cambridge, England : 2003) 20121014

Lead(II)-catalyzed oxidation of guanine in solution studied with electrospray ionization mass spectrometry.

The journal of physical chemistry. B 20121004

Nucleoside analogue electrochemical behaviour and in situ evaluation of DNA-clofarabine interaction.

Bioelectrochemistry (Amsterdam, Netherlands) 20121001

Effects of chronic guanosine treatment on hippocampal damage and cognitive impairment of rats submitted to chronic cerebral hypoperfusion.

Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology 20121001

Combining redox-proteomics and epigenomics to explain the involvement of oxidative stress in psychiatric disorders.

Molecular bioSystems 20121001

Guanosine produces an antidepressant-like effect through the modulation of NMDA receptors, nitric oxide-cGMP and PI3K/mTOR pathways.

Behavioural brain research 20121001

Identification and expression profiles of ADAR1 gene, responsible for RNA editing, in responses to dsRNA and GCRV challenge in grass carp (Ctenopharyngodon idella).

Fish & shellfish immunology 20121001

Eukaryotic initiation factor 5B: a new player for the anti-hepatitis C virus effect of ribavirin?

Medical hypotheses 20121001

In vivo and in vitro animal investigation of the effect of a mixture of herbal extracts from Tribulus terrestris and Cornus officinalis on penile erection.

The journal of sexual medicine 20121001

C8-linked bulky guanosine DNA adducts: experimental and computational insights into adduct conformational preferences and resulting mutagenicity.

Future medicinal chemistry 20121001

Filament formation of the FtsZ/tubulin-like protein TubZ from the Bacillus cereus pXO1 plasmid.

The Journal of biological chemistry 20120914

Benchmark studies on the building blocks of DNA. 2. Effect of biological environment on the electronic excitation spectrum of nucleobases.

The journal of physical chemistry. A 20120906

Oxidative damage of DNA, RNA and their metabolites in leukocytes, plasma and urine of Macaca mulatta: 8-oxoguanosine in urine is a useful marker for aging.

Free radical research 20120901

Sex differences in the Nociceptin/Orphanin FQ system in rat spinal cord following chronic morphine treatment.

Neuropharmacology 20120901

The mu opioid receptor modulates neurotransmission in the rat spinal ventral horn.

Anesthesia and analgesia 20120901

Sphingosine 1-phosphate receptor 2 antagonist JTE-013 increases the excitability of sensory neurons independently of the receptor.

Journal of neurophysiology 20120901

Cooperation of non-effective concentration of glutamatergic system modulators and antioxidant against oxidative stress induced by quinolinic acid.

Neurochemical research 20120901

Mycophenolate mofetil inhibits hepatitis C virus replication in human hepatic cells.

Virus research 20120901

Box H/ACA snoRNAs are preferred substrates for the trimethylguanosine synthase in the divergent unicellular eukaryote Trichomonas vaginalis.

RNA (New York, N.Y.) 20120901

Recognition of guanosine by dissimilar tRNA methyltransferases.

RNA (New York, N.Y.) 20120901

High genomic instability predicts survival in metastatic high-risk neuroblastoma.

Neoplasia (New York, N.Y.) 20120901

TLR13 recognizes bacterial 23S rRNA devoid of erythromycin resistance-forming modification.

Science (New York, N.Y.) 20120831

Characterization of heterotrimeric nucleotide-depleted Gα(i)-proteins by Bodipy-FL-GTPγS fluorescence anisotropy.

Archives of biochemistry and biophysics 20120815

RNA oxidation catalyzed by cytochrome c leads to its depurination and cross-linking, which may facilitate cytochrome c release from mitochondria.

Free radical biology & medicine 20120815

A new imidazolium-embedded C18 stationary phase with enhanced performance in reversed-phase liquid chromatography.

Analytica chimica acta 20120813

Thermodynamics of the GTP-GDP-operated conformational switch of selenocysteine-specific translation factor SelB.

The Journal of biological chemistry 20120810

Protective effects of guanosine against sepsis-induced damage in rat brain and cognitive impairment.

Brain, behavior, and immunity 20120801

An intravaginal ring for the simultaneous delivery of multiple drugs.

Journal of pharmaceutical sciences 20120801

Mitofusins and the mitochondrial permeability transition: the potential downside of mitochondrial fusion.

American journal of physiology. Heart and circulatory physiology 20120801

Activation of heme oxygenase and suppression of cGMP are associated with impaired endothelial function in obstructive sleep apnea with hypertension.

American journal of hypertension 20120801

Interaction of liposome-encapsulated cisplatin with biomolecules.

Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry 20120801

Guanosine protects human neuroblastoma SH-SY5Y cells against mitochondrial oxidative stress by inducing heme oxigenase-1 via PI3K/Akt/GSK-3β pathway.

Neurochemistry international 20120801

Synthesis and in vitro stability of nucleoside 5'-phosphonate derivatives.

European journal of medicinal chemistry 20120801

Intractable absence seizures in hyperinsulinism-hyperammonemia syndrome.

Pediatric neurology 20120801

Increased gene expression of the ABCC5 transporter without distinct changes in the expression of PDE5 in human cervical cancer cells during growth.

Anticancer research 20120801

Nascent-seq indicates widespread cotranscriptional RNA editing in Drosophila.

Molecular cell 20120713

Differential regulation by cyclic nucleotides of the CNGA4 and CNGB1b subunits in olfactory cyclic nucleotide-gated channels.

Science signaling 20120710

Solution structure of the N-terminal dsRBD of Drosophila ADAR and interaction studies with RNA.

Biochimie 20120701

Development of operational models of receptor activation including constitutive receptor activity and their use to determine the efficacy of the chemokine CCL17 at the CC chemokine receptor CCR4.

British journal of pharmacology 20120701

The histamine autoreceptor is a short isoform of the H₃ receptor.

British journal of pharmacology 20120701

Sar1 translocation onto the ER-membrane for vesicle budding has different pathways for promotion and suppression of ER-to-Golgi transport mediated through H89-sensitive kinase and ER-resident G protein.

Molecular and cellular biochemistry 20120701

Next-generation sequencing offers new insights into DNA degradation.

Trends in biotechnology 20120701

Stacked and continuous helical self-assemblies of guanosine monophosphates detected by vibrational circular dichroism.

Analytical and bioanalytical chemistry 20120701

Detection and typing of viruses using broadly sensitive cocktail-PCR and mass spectrometric cataloging: demonstration with dengue virus.

The Journal of molecular diagnostics : JMD 20120701

Retinal remodeling.

Japanese journal of ophthalmology 20120701

Estrogen receptor alpha modulates Toll-like receptor signaling in murine lupus.

Clinical immunology (Orlando, Fla.) 20120701

Structure of STING bound to cyclic di-GMP reveals the mechanism of cyclic dinucleotide recognition by the immune system.

Nature structural & molecular biology 20120701

Dose-dependent response of dendritic cells to 7-thia-8-oxo-guanosine and its modulation by polyinosinic:polycytidylic acid.

Experimental biology and medicine (Maywood, N.J.) 20120701

Identification of interaction partners of the dynamin-like protein DynA from Bacillus subtilis.

Communicative & integrative biology 20120701

Cyclic di-GMP sensing via the innate immune signaling protein STING.

Molecular cell 20120629

New quinoxaline derivatives as potential MT₁ and MT₂ receptor ligands.

Molecules (Basel, Switzerland) 20120625

Crystal structures of STING protein reveal basis for recognition of cyclic di-GMP.

Nature structural & molecular biology 20120624

Potential of the NBP method for the study of alkylation mechanisms: NBP as a DNA-model.

Chemical research in toxicology 20120618

Tax protein-induced expression of antiapoptotic Bfl-1 protein contributes to survival of human T-cell leukemia virus type 1 (HTLV-1)-infected T-cells.

The Journal of biological chemistry 20120615

Human MTH3 (NUDT18) protein hydrolyzes oxidized forms of guanosine and deoxyguanosine diphosphates: comparison with MTH1 and MTH2.

The Journal of biological chemistry 20120615

Matrix rigidity controls endothelial differentiation and morphogenesis of cardiac precursors.

Science signaling 20120605

Transcriptional profile of GTP-mediated differentiation of C2C12 skeletal muscle cells.

Purinergic signalling 20120601

Collection and storage of red blood cells with anticoagulant and additive solution with a physiologic pH.

Transfusion 20120601

The regulation of cardiac activity by nitric oxide (NO) in the Vietnamese stick insect, Baculum extradentatum.

Cellular signalling 20120601

Distinct pattern of oxidative DNA damage and DNA repair in follicular thyroid tumours.

Journal of molecular endocrinology 20120601

Novel role of NF-κB-p65 in antioxidant homeostasis in human kidney-2 cells.

American journal of physiology. Renal physiology 20120601

Computational insights into the inhibition of inosine 5'-monophosphate dehydrogenase by mycophenolic acid analogs: three-dimensional quantitative structure-activity relationship and molecular docking studies.

Chemical biology & drug design 20120601

Receptor conformations involved in dopamine D(2L) receptor functional selectivity induced by selected transmembrane-5 serine mutations.

Molecular pharmacology 20120601

Adenosine modification may be preferred for reducing siRNA immune stimulation.

Nucleic acid therapeutics 20120601

Deep EST profiling of developing fenugreek endosperm to investigate galactomannan biosynthesis and its regulation.

Plant molecular biology 20120601

Fluorometric detection of adenine in target DNA by exciplex formation with fluorescent 8-arylethynylated deoxyguanosine.

Bioorganic & medicinal chemistry letters 20120601

Exploring purine N7 interactions via atomic mutagenesis: the group I ribozyme as a case study.

RNA (New York, N.Y.) 20120601

A novel sulindac derivative that potently suppresses colon tumor cell growth by inhibiting cGMP phosphodiesterase and β-catenin transcriptional activity.

Cancer prevention research (Philadelphia, Pa.) 20120601

E2F1-dependent methyl cap formation requires RNA pol II phosphorylation.

Cell cycle (Georgetown, Tex.) 20120601

The circadian neuropeptide PDF signals preferentially through a specific adenylate cyclase isoform AC3 in M pacemakers of Drosophila.

PLoS biology 20120601

Two-step, one-pot synthesis of inosine, guanosine, and 2'-deoxyguanosine O6-ethers via intermediate O6-(benzotriazol-1-yl) derivatives.

Current protocols in nucleic acid chemistry 20120601

Bridging QTAIM with vibrational spectroscopy: the energy of intramolecular hydrogen bonds in DNA-related biomolecules.

Physical chemistry chemical physics : PCCP 20120528

Ionic liquids promote PCR amplification of DNA.

Chemical communications (Cambridge, England) 20120528

The DNA damage checkpoint protein ATM promotes hepatocellular apoptosis and fibrosis in a mouse model of non-alcoholic fatty liver disease.

Cell cycle (Georgetown, Tex.) 20120515

Signal transduction pathway activity compensates dopamine D₂/D₃ receptor density changes in Parkinson's disease: a preliminary comparative human brain receptor autoradiography study with [³H]raclopride and [³⁵S]GTPγS.

Brain research 20120509

Diffusion and birefringence of bioactive dyes in a supramolecular guanosine hydrogel.

Chemistry (Weinheim an der Bergstrasse, Germany) 20120507

Exploring light and life.

The Journal of biological chemistry 20120504

A-to-I editing of microRNAs: regulating the regulators?

Seminars in cell & developmental biology 20120501

Sensitivity to μ-opioid receptor-mediated anti-nociception is determined by cross-regulation between μ- and δ-opioid receptors at supraspinal level.

British journal of pharmacology 20120501

The intricate relationship between RNA structure, editing, and splicing.

Seminars in cell & developmental biology 20120501

Lysophosphatidylinositol stimulates [³⁵S]GTPγS binding in the rat prefrontal cortex and hippocampus.

Neurochemical research 20120501

Hydrostatic and osmotic pressure study of the RNA hydration.

Molecular biology reports 20120501

Acetylcholine-evoked afterdischarge in Aplysia bag cell neurons.

Journal of neurophysiology 20120501

Age-dependent increases in the oxidative damage of DNA, RNA, and their metabolites in normal and senescence-accelerated mice analyzed by LC-MS/MS: urinary 8-oxoguanosine as a novel biomarker of aging.

Free radical biology & medicine 20120501

Synthesis and biological evaluation of a series of thieno-expanded tricyclic purine 2'-deoxy nucleoside analogues.

Bioorganic & medicinal chemistry 20120501

Novel peptide for attenuation of hypoxia-induced pulmonary hypertension via modulation of nitric oxide release and phosphodiesterase -5 activity.

Peptides 20120501

Enzymatic synthesis of 8-vinyl- and 8-styryl-2'-deoxyguanosine modified DNA--novel fluorescent molecular probes.

Bioorganic & medicinal chemistry letters 20120501

Statistical parametric mapping reveals regional alterations in cannabinoid CB1 receptor distribution and G-protein activation in the 3D reconstructed epileptic rat brain.

Epilepsia 20120501

Supramolecular arrangement of guanosine/5-guanosine monophosphate binary mixtures studied by methods of circular dichroism.

Chirality 20120501

Structure and functional analysis of the RNA- and viral phosphoprotein-binding domain of respiratory syncytial virus M2-1 protein.

PLoS pathogens 20120501

Synthesis, binding affinity, and functional in vitro activity of 3-benzylaminomorphinan and 3-benzylaminomorphine ligands at opioid receptors.

Journal of medicinal chemistry 20120426

Signaling property study of adhesion G-protein-coupled receptors.

FEBS letters 20120424

β-arrestin2 regulates cannabinoid CB1 receptor signaling and adaptation in a central nervous system region-dependent manner.

Biological psychiatry 20120415

Structural basis for dual nucleotide selectivity of aminoglycoside 2''-phosphotransferase IVa provides insight on determinants of nucleotide specificity of aminoglycoside kinases.

The Journal of biological chemistry 20120413

Allosteric modulator ORG27569 induces CB1 cannabinoid receptor high affinity agonist binding state, receptor internalization, and Gi protein-independent ERK1/2 kinase activation.

The Journal of biological chemistry 20120406

Geissoschizine methyl ether, an alkaloid in Uncaria hook, is a potent serotonin ₁A receptor agonist and candidate for amelioration of aggressiveness and sociality by yokukansan.

Neuroscience 20120405

Assignments of backbone ¹H, ¹³C and ¹⁵N resonances in H-Ras (1-166) complexed with GppNHp at physiological pH.

Biomolecular NMR assignments 20120401

In vivo characterization of several rodent glioma models by 1H MRS.

NMR in biomedicine 20120401

DNA damage in lead-exposed hepatocytes: coexistence of apoptosis and necrosis?

Drug and chemical toxicology 20120401

Hormonal control of mammalian oocyte meiosis at diplotene stage.

Cellular and molecular life sciences : CMLS 20120401

Induction of apoptosis by type Iβ protein kinase G in the human breast cancer cell lines MCF-7 and MDA-MB-468.

Cell biochemistry and function 20120401

Selective recognition and separation of nucleosides using carboxymethyl-β-cyclodextrin functionalized hybrid magnetic nanoparticles.

Colloids and surfaces. B, Biointerfaces 20120401

Hydrogen gas ameliorates oxidative stress in early brain injury after subarachnoid hemorrhage in rats.

Critical care medicine 20120401

Probes for narcotic receptor mediated phenomena. 44. Synthesis of an N-substituted 4-hydroxy-5-(3-hydroxyphenyl)morphan with high affinity and selective μ-antagonist activity.

European journal of medicinal chemistry 20120401

Mechanism of substrate selection by a highly specific CRISPR endoribonuclease.

RNA (New York, N.Y.) 20120401

The synthesis of 2'-methylseleno adenosine and guanosine 5'-triphosphates.

Bioorganic & medicinal chemistry 20120401

Separation of nucleobases and their derivatives with organic-high ionic strength aqueous phase systems by spiral high-speed counter-current chromatography.

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20120401

Loxoribine pretreatment reduces Salmonella Enteritidis organ invasion in 1-day-old chickens.

Poultry science 20120401

A RelA-dependent two-tiered regulated proteolysis cascade controls synthesis of a contact-dependent intercellular signal in Myxococcus xanthus.

Molecular microbiology 20120401

Exploiting structure similarity in refinement: automated NCS and target-structure restraints in BUSTER.

Acta crystallographica. Section D, Biological crystallography 20120401

Structural basis for type VI secretion effector recognition by a cognate immunity protein.

PLoS pathogens 20120401

The Caenorhabditis elegans HEN1 ortholog, HENN-1, methylates and stabilizes select subclasses of germline small RNAs.

PLoS genetics 20120401

First total synthesis of a naturally occurring iodinated 5'-deoxyxylofuranosyl marine nucleoside.

Marine drugs 20120401

[Dynamic accumulation of dry matter and active element in Pinellia ternata of Taizhou].

Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20120401

Effects of ginsenoside on pacemaker potentials of cultured interstitial cells of Cajal clusters from the small intestine of mice.

Molecules and cells 20120331

The structural basis of the kinetic mechanism of a gap-filling X-family DNA polymerase that binds Mg(2+)-dNTP before binding to DNA.

Journal of molecular biology 20120330

The butter flavorant, diacetyl, forms a covalent adduct with 2-deoxyguanosine, uncoils DNA, and leads to cell death.

Journal of agricultural and food chemistry 20120328

δ-opioid receptor function in the dorsal striatum plays a role in high levels of ethanol consumption in rats.

The Journal of neuroscience : the official journal of the Society for Neuroscience 20120328

2'-Azido RNA, a versatile tool for chemical biology: synthesis, X-ray structure, siRNA applications, click labeling.

ACS chemical biology 20120316

Preparation of methacrylate-based monolith for capillary hydrophilic interaction chromatography and its application in determination of nucleosides in urine.

Journal of chromatography. A 20120309

Biochemical characterization of ribosome assembly GTPase RbgA in Bacillus subtilis.

The Journal of biological chemistry 20120309

Properties of an LNA-modified ricin RNA aptamer.

Biochemical and biophysical research communications 20120302

The delta opioid receptor antagonist, SoRI-9409, decreases yohimbine stress-induced reinstatement of ethanol-seeking.

Addiction biology 20120301

YQA14: a novel dopamine D3 receptor antagonist that inhibits cocaine self-administration in rats and mice, but not in D3 receptor-knockout mice.

Addiction biology 20120301

Increased ethanol intake in prodynorphin knockout mice is associated to changes in opioid receptor function and dopamine transmission.

Addiction biology 20120301

Synthesis of novel Eu(III) luminescent probe based on 9- acridinecarboxylic acid skelton for sensing of ds-DNA.

Journal of fluorescence 20120301

Wild-type and feedback-resistant phosphoribosyl pyrophosphate synthetases from Bacillus amyloliquefaciens: purification, characterization, and application to increase purine nucleoside production.

Applied microbiology and biotechnology 20120301

[(35)S]GTPγS binding and opioid tolerance and efficacy in mouse spinal cord.

Pharmacology, biochemistry, and behavior 20120301

Characterization of COR627 and COR628, two novel positive allosteric modulators of the GABA(B) receptor.

The Journal of pharmacology and experimental therapeutics 20120301

Modulation of guanosine nucleotides biosynthetic pathways enhanced GDP-L-fucose production in recombinant Escherichia coli.

Applied microbiology and biotechnology 20120301

Epigenetic modifications in cardiovascular disease.

Basic research in cardiology 20120301

The earliest stage of cognitive impairment in transition from normal aging to Alzheimer disease is marked by prominent RNA oxidation in vulnerable neurons.

Journal of neuropathology and experimental neurology 20120301

Two-step efficient synthesis of 5-methyluridine via two thermostable nucleoside phosphorylase from Aeropyrum pernix.

Bioorganic & medicinal chemistry letters 20120301

A corrected space group for Sulfolobus sulfataricus 5'-deoxy-5'-methylthioadenosine phosphorylase II.

Acta crystallographica. Section D, Biological crystallography 20120301

Short ORF-dependent ribosome shunting operates in an RNA picorna-like virus and a DNA pararetrovirus that cause rice tungro disease.

PLoS pathogens 20120301

Two programmed cell death systems in Escherichia coli: an apoptotic-like death is inhibited by the mazEF-mediated death pathway.

PLoS biology 20120301

Quantitative Proteomics of Intracellular Campylobacter jejuni Reveals Metabolic Reprogramming.

PLoS pathogens 20120301

Statistical analysis of readthrough levels for nonsense mutations in mammalian cells reveals a major determinant of response to gentamicin.

PLoS genetics 20120301

B-type natriuretic Peptide assay for the diagnosis and prognosis of patent ductus arteriosus in preterm infants.

Korean circulation journal 20120301

Online extraction and isolation of highly polar chemical constituents from Brassica napus L. pollen by high shear technique coupled with high-performance counter-current chromatography.

Journal of separation science 20120301

Pharmacokinetics of mycophenolic acid and its phenyl glucuronide metabolite in kidney transplant recipients with renal impairment.

Archives of medical science : AMS 20120227

Aberrant cyclization affords a C-6 modified cyclic adenosine 5'-diphosphoribose analogue with biological activity in Jurkat T cells.

Journal of medicinal chemistry 20120223

Oxidation of the antiviral drug acyclovir and its biodegradation product carboxy-acyclovir with ozone: kinetics and identification of oxidation products.

Environmental science & technology 20120221

Selection of monoclonal antibodies against 6-oxo-M(1)dG and their use in an LC-MS/MS assay for the presence of 6-oxo-M(1)dG in vivo.

Chemical research in toxicology 20120220

Supramolecular dendrimers: convenient synthesis by programmed self-assembly and tunable thermoresponsivity.

Chemistry (Weinheim an der Bergstrasse, Germany) 20120220

Diversity of archaeosine synthesis in crenarchaeota.

ACS chemical biology 20120217

Biochemical identification of a hydroperoxide derivative of the free 8-oxo-7,8-dihydroguanine base.

Free radical biology & medicine 20120215

Base pairing at the abasic site in DNA duplexes and its application in adenosine aptasensors.

Chembiochem : a European journal of chemical biology 20120213

Ras-related GTPases Rap1 and RhoA collectively induce the phagocytosis of serum-opsonized zymosan particles in macrophages.

The Journal of biological chemistry 20120210

Short-RNA selective binding of oligonucleotides modified using adenosine and guanosine derivatives that possess cyclohexyl phosphates as substituents.

Organic & biomolecular chemistry 20120207

High constitutive activity is an intrinsic feature of ghrelin receptor protein: a study with a functional monomeric GHS-R1a receptor reconstituted in lipid discs.

The Journal of biological chemistry 20120203

A nucleotide phosphatase activity in the nucleotide binding domain of an orphan resistance protein from rice.

The Journal of biological chemistry 20120203

Oxidative damage to guanine nucleosides following combination chemotherapy with 5-fluorouracil and oxaliplatin.

Cancer chemotherapy and pharmacology 20120201

Nitric oxide synthase and cyclic GMP signaling in cardiac myocytes: from contractility to remodeling.

Journal of molecular and cellular cardiology 20120201

Chronic treatment with the opioid antagonist naltrexone favours the coupling of spinal cord μ-opioid receptors to Gαz protein subunits.

Neuropharmacology 20120201

3',4'-Dihydroxyflavonol reduces vascular contraction through Ca²⁺ desensitization in permeabilized rat mesenteric artery.

Naunyn-Schmiedeberg's archives of pharmacology 20120201

Formation and characterization of covalent guanosine adducts with electrochemistry-liquid chromatography-mass spectrometry.

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20120201

The basic property of Lys385 is important for potentiation of the human α1 glycine receptor by ethanol.

The Journal of pharmacology and experimental therapeutics 20120201

3-Substituted pyrazole analogs of the cannabinoid type 1 (CB₁) receptor antagonist rimonabant: cannabinoid agonist-like effects in mice via non-CB₁, non-CB₂ mechanism.

The Journal of pharmacology and experimental therapeutics 20120201

Muscarinic receptor/G-protein coupling is reduced in the dorsomedial striatum of cognitively impaired aged rats.

Behavioural brain research 20120201

Mechanisms of systemic vasodilation by lysozyme-c in septic shock.

Journal of applied physiology (Bethesda, Md. : 1985) 20120201

Analyzing the metabolic stress response of recombinant Escherichia coli cultures expressing human interferon-beta in high cell density fed batch cultures using time course transcriptomic data.

Molecular bioSystems 20120201

Identification and characterization of mutations in the promoter region of the factor VIII gene.

Journal of thrombosis and haemostasis : JTH 20120201

Structures of NodZ α1,6-fucosyltransferase in complex with GDP and GDP-fucose.

Acta crystallographica. Section D, Biological crystallography 20120201

Chemical fingerprint analysis of Fritillaria delavayi Franch. by high-performance liquid chromatography.

Journal of separation science 20120201

An optimized electrochemistry-liquid chromatography-mass spectrometry method for studying guanosine oxidation.

Electrophoresis 20120201

Characterization of RNA damage under oxidative stress in Escherichia coli.

Biological chemistry 20120201

Functional promiscuity of the COG0720 family.

ACS chemical biology 20120120

Oligomer formation of the bacterial second messenger c-di-GMP: reaction rates and equilibrium constants indicate a monomeric state at physiological concentrations.

Journal of the American Chemical Society 20120118

The inverse agonist effect of rimonabant on G protein activation is not mediated by the cannabinoid CB1 receptor: evidence from postmortem human brain.

Biochemical pharmacology 20120115

Lung endothelial Ca2+ and permeability response to platelet-activating factor is mediated by acid sphingomyelinase and transient receptor potential classical 6.

American journal of respiratory and critical care medicine 20120115

R-Isovaline: a subtype-specific agonist at GABA(B)-receptors?

Neuroscience 20120110

Hydrogen sulfide as a cryogenic mediator of hypoxia-induced anapyrexia.

Neuroscience 20120110

Kinetic analysis of 3'-5' nucleotide addition catalyzed by eukaryotic tRNA(His) guanylyltransferase.

Biochemistry 20120110

In vitro selection and characterization of a novel Zn(II)-dependent phosphorothiolate thiolesterase ribozyme.

Biochemistry 20120110

The combination of organoselenium compounds and guanosine prevents glutamate-induced oxidative stress in different regions of rat brains.

Brain research 20120109

SK channel modulation rescues striatal plasticity and control over habit in cannabinoid tolerance.

Nature neuroscience 20120108

Enhancement of affinity in molecular recognition via hydrogen bonds by POSS-core dendrimer and its application for selective complex formation between guanosine triphosphate and 1,8-naphthyridine derivatives.

Organic & biomolecular chemistry 20120107

Incoherent feedforward control governs adaptation of activated ras in a eukaryotic chemotaxis pathway.

Science signaling 20120103

Erectogenic Effects of Clerodendron capitatum: Involvement of Phosphodiesterase Type-5 Inhibition.

Evidence-based complementary and alternative medicine : eCAM 20120101

Modulation of microRNA expression and function by ADARs.

Current topics in microbiology and immunology 20120101

Interdependency of cystathione γ-lyase and cystathione β-synthase in hydrogen sulfide-induced blood pressure regulation in rats.

American journal of hypertension 20120101

Toll-like receptor 7 ligands inhibit influenza A infection in chickens.

Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research 20120101

Evidence that hyperprolinemia alters glutamatergic homeostasis in rat brain: neuroprotector effect of guanosine.

Neurochemical research 20120101

GABAB receptor-positive modulators: brain region-dependent effects.

The Journal of pharmacology and experimental therapeutics 20120101

The relaxation effect and mechanism of action of higenamine in the rat corpus cavernosum.

International journal of impotence research 20120101

Protein Glycosylation in Aspergillus fumigatus Is Essential for Cell Wall Synthesis and Serves as a Promising Model of Multicellular Eukaryotic Development.

International journal of microbiology 20120101

Oxidative stress, mitochondrial dysfunction, and aging.

Journal of signal transduction 20120101

Probe dependence in the allosteric modulation of a G protein-coupled receptor: implications for detection and validation of allosteric ligand effects.

Molecular pharmacology 20120101

CEP-26401 (irdabisant), a potent and selective histamine H₃ receptor antagonist/inverse agonist with cognition-enhancing and wake-promoting activities.

The Journal of pharmacology and experimental therapeutics 20120101

Protection from myocardial ischemia/reperfusion injury by a positive allosteric modulator of the A₃ adenosine receptor.

The Journal of pharmacology and experimental therapeutics 20120101

Inhibition of Junin virus RNA synthesis by an antiviral acridone derivative.

Antiviral research 20120101

Oligodeoxynucleotides inhibit Toll-like receptor 3 mediated cytotoxicity and CXCL8 release in keratinocytes.

Experimental dermatology 20120101

Identification of the muscarinic pathway underlying cessation of sleep-related burst activity in rat thalamocortical relay neurons.

Pflugers Archiv : European journal of physiology 20120101

Asymmetry of 13C labeled 3-pyruvate affords improved site specific labeling of RNA for NMR spectroscopy.

Journal of biomolecular NMR 20120101

ppGpp inhibits peptide elongation cycle of chloroplast translation system in vitro.

Plant molecular biology 20120101

Genetics and Gene Expression Involving Stress and Distress Pathways in Fibromyalgia with and without Comorbid Chronic Fatigue Syndrome.

Pain research and treatment 20120101

A new proofreading mechanism for lesion bypass by DNA polymerase-λ.

EMBO reports 20120101

Blocking type I interferon production: a new therapeutic option to reduce the HIV-1-induced immune activation.

Clinical & developmental immunology 20120101

Advancements in Z-DNA: development of inducers and stabilizers for B to Z transition.

Current medicinal chemistry 20120101

A computational perspective of molecular interactions through virtual screening, pharmacokinetic and dynamic prediction on ribosome toxin A chain and inhibitors of Ricinus communis.

Pharmacognosy research 20120101

Effects of inhaled nitric oxide on hemostasis in healthy adults treated with heparin: a randomized, controlled, blinded crossover study.

Thrombosis journal 20120101

Posttranscriptional recoding by RNA editing.

Advances in protein chemistry and structural biology 20120101

Antisense sequencing improves the accuracy and precision of A-to-I editing measurements using the peak height ratio method.

BMC research notes 20120101

Tyrosine nitration of PA700 links proteasome activation to endothelial dysfunction in mouse models with cardiovascular risk factors.

PloS one 20120101

HIV-1 polymerase inhibition by nucleoside analogs: cellular- and kinetic parameters of efficacy, susceptibility and resistance selection.

PLoS computational biology 20120101

Platelet inhibition by nitrite is dependent on erythrocytes and deoxygenation.

PloS one 20120101

The ζ toxin induces a set of protective responses and dormancy.

PloS one 20120101

Differential treatment regimen-related effects of HU210 on CB(1) and D(2)-like receptor functionality in the rat basal ganglia.

Pharmacology 20120101

Non coding RNAs and viruses in the framework of the phylogeny of the genes, epigenesis and heredity.

International journal of molecular sciences 20120101

A case of persistent foot pain in a neurofibromatosis type I patient.

Case reports in medicine 20120101

Insertion site preference of Mu, Tn5, and Tn7 transposons.

Mobile DNA 20120101

Complexity of murine cardiomyocyte miRNA biogenesis, sequence variant expression and function.

PloS one 20120101

Chemical approaches for structure and function of RNA in postgenomic era.

Journal of nucleic acids 20120101

Cystinosin, MPDU1, SWEETs and KDELR belong to a well-defined protein family with putative function of cargo receptors involved in vesicle trafficking.

PloS one 20120101

Gene profile of myeloid-derived suppressive cells from the bone marrow of lysosomal acid lipase knock-out mice.

PloS one 20120101

NCAM180 regulates Ric8A membrane localization and potentiates β-adrenergic response.

PloS one 20120101

Active site mutations change the cleavage specificity of neprilysin.

PloS one 20120101

Specific Cooperation Between Imp-α2 and Imp-β/Ketel in Spindle Assembly During Drosophila Early Nuclear Divisions.

G3 (Bethesda, Md.) 20120101

Discovery of inhibitors of Leishmania β-1,2-mannosyltransferases using a click-chemistry-derived guanosine monophosphate library.

PloS one 20120101

On docking, scoring and assessing protein-DNA complexes in a rigid-body framework.

PloS one 20120101

CSF concentrations of cAMP and cGMP are lower in patients with Creutzfeldt-Jakob disease but not Parkinson's disease and amyotrophic lateral sclerosis.

PloS one 20120101

Epigenetic disregulation in oral cancer.

International journal of molecular sciences 20120101

Expression of Tas1 taste receptors in mammalian spermatozoa: functional role of Tas1r1 in regulating basal Ca²⁺ and cAMP concentrations in spermatozoa.

PloS one 20120101

Menopausal status modifies breast cancer risk associated with the myeloperoxidase (MPO) G463A polymorphism in Caucasian women: a meta-analysis.

PloS one 20120101

Suppression of ribosomal protein synthesis and protein translation factors by Peg-interferon alpha/ribavirin in HCV patients blood mononuclear cells (PBMC).

Journal of translational medicine 20120101

Direct Antioxidant Properties of Bilirubin and Biliverdin. Is there a Role for Biliverdin Reductase?

Frontiers in pharmacology 20120101

Reversal of cocaine-conditioned place preference through methyl supplementation in mice: altering global DNA methylation in the prefrontal cortex.

PloS one 20120101

Reversal of the ΔdegP phenotypes by a novel rpoE allele of Escherichia coli.

PloS one 20120101

Dynamic 5-HT2C receptor editing in a mouse model of obesity.

PloS one 20120101

Nebivolol: impact on cardiac and endothelial function and clinical utility.

Vascular health and risk management 20120101

Hesperetin, a Selective Phosphodiesterase 4 Inhibitor, Effectively Suppresses Ovalbumin-Induced Airway Hyperresponsiveness without Influencing Xylazine/Ketamine-Induced Anesthesia.

Evidence-based complementary and alternative medicine : eCAM 20120101

Comparison of the effects of adenosine, inosine, and their combination as an adjunct to reperfusion in the treatment of acute myocardial infarction.

ISRN cardiology 20120101

Tissue distribution and metabolism of guanosine in rats following intraperitoneal injection.

Journal of biological regulators and homeostatic agents 20120101

Identification of novel Mt-Guab2 inhibitor series active against M. tuberculosis.

PloS one 20120101

The protein partners of GTP cyclohydrolase I in rat organs.

PloS one 20120101

Temporal patterns of nucleotide misincorporations and DNA fragmentation in ancient DNA.

PloS one 20120101

Spironolactone lowers portal hypertension by inhibiting liver fibrosis, ROCK-2 activity and activating NO/PKG pathway in the bile-duct-ligated rat.

PloS one 20120101

Stimulators and activators of soluble guanylate cyclase: review and potential therapeutic indications.

Critical care research and practice 20120101

Silencing of amyloid precursor protein expression using a new engineered delta ribozyme.

International journal of Alzheimer's disease 20120101

Development of on-line high performance liquid chromatography (HPLC)-biochemical detection methods as tools in the identification of bioactives.

International journal of molecular sciences 20120101

The Immune Response to Trypanosoma cruzi: Role of Toll-Like Receptors and Perspectives for Vaccine Development.

Journal of parasitology research 20120101

Epigallocatechin-3-gallate has an anti-platelet effect in a cyclic AMP-dependent manner.

Journal of atherosclerosis and thrombosis 20120101

Spherical lactic acid bacteria activate plasmacytoid dendritic cells immunomodulatory function via TLR9-dependent crosstalk with myeloid dendritic cells.

PloS one 20120101

Functional characterization of EngA(MS), a P-loop GTPase of Mycobacterium smegmatis.

PloS one 20120101

Heme oxygenase-1 induction and organic nitrate therapy: beneficial effects on endothelial dysfunction, nitrate tolerance, and vascular oxidative stress.

International journal of hypertension 20120101

Gasotransmitters: novel regulators of epithelial na(+) transport?

Frontiers in physiology 20120101

Complexity of the Mycoplasma fermentans M64 genome and metabolic essentiality and diversity among mycoplasmas.

PloS one 20120101

The essential role of AMPA receptor GluR2 subunit RNA editing in the normal and diseased brain.

Frontiers in molecular neuroscience 20120101

Identification and characterization of two novel RNA editing sites in grin1b transcripts of embryonic Danio rerio.

Neural plasticity 20120101

Alternative Mechanisms to Initiate Translation in Eukaryotic mRNAs.

Comparative and functional genomics 20120101

A novel k-mer mixture logistic regression for methylation susceptibility modeling of CpG dinucleotides in human gene promoters.

BMC bioinformatics 20120101

Role of neural NO synthase (nNOS) uncoupling in the dysfunctional nitrergic vasorelaxation of penile arteries from insulin-resistant obese Zucker rats.

PloS one 20120101

Structure of an enzyme-derived phosphoprotein recognition domain.

PloS one 20120101

Whole cell biosynthesis of a functional oligosaccharide, 2'-fucosyllactose, using engineered Escherichia coli.

Microbial cell factories 20120101

Disrupting the Acyl Carrier Protein/SpoT interaction in vivo: identification of ACP residues involved in the interaction and consequence on growth.

PloS one 20120101

Risk factors for persistent pulmonary hypertension of the newborn.

Pulmonary circulation 20120101

Kaposi's Sarcoma-Associated Herpesvirus microRNAs.

Frontiers in microbiology 20120101

Comparative genomics reveals adaptation by Alteromonas sp. SN2 to marine tidal-flat conditions: cold tolerance and aromatic hydrocarbon metabolism.

PloS one 20120101

Down-regulation of GABA(A) receptor via promiscuity with the vasoactive peptide urotensin II receptor. Potential involvement in astrocyte plasticity.

PloS one 20120101

Type I interferons as ambiguous modulators of chronic inflammation in the central nervous system.

Frontiers in immunology 20120101

Time dependent neuroprotection of mycophenolate mofetil: effects on temporal dynamics in glial proliferation, apoptosis, and scar formation.

Journal of neuroinflammation 20120101

Regulation of the proteasome by AMPK in endothelial cells: the role of O-GlcNAc transferase (OGT).

PloS one 20120101

Endothelial dysfunction and diabetes: effects on angiogenesis, vascular remodeling, and wound healing.

International journal of vascular medicine 20120101

Electrochemical detection of individual single nucleotide polymorphisms using monobase-modified apoferritin-encapsulated nanoparticles.

Biosensors & bioelectronics 20120101

Low affinity GPCRs for metabolic intermediates: challenges for pharmacologists.

Frontiers in endocrinology 20120101

Hepatoprotective Effects of Panus giganteus (Berk.) Corner against Thioacetamide- (TAA-) Induced Liver Injury in Rats.

Evidence-based complementary and alternative medicine : eCAM 20120101

Back to basics: pitting edema and the optimization of hypertension treatment in incident peritoneal dialysis patients (BRAZPD).

PloS one 20120101

M. tuberculosis induces potent activation of IDO-1, but this is not essential for the immunological control of infection.

PloS one 20120101

NF-κB repression by PIAS3 mediated RelA SUMOylation.

PloS one 20120101

Chemical constituents and biological activities of the genus Subergorgia.

Pharmacognosy reviews 20120101

The evolving landscape of neurotoxicity by unconjugated bilirubin: role of glial cells and inflammation.

Frontiers in pharmacology 20120101

Targeting tumor perfusion and oxygenation to improve the outcome of anticancer therapy.

Frontiers in pharmacology 20120101

Pan-pathway based interaction profiling of FDA-approved nucleoside and nucleobase analogs with enzymes of the human nucleotide metabolism.

PloS one 20120101

Down-regulation of GEP100 causes increase in E-cadherin levels and inhibits pancreatic cancer cell invasion.

PloS one 20120101

Radiolabeled nucleosides for predicting and monitoring the cancer therapeutic efficacy of chemodrugs.

Current medicinal chemistry 20120101

Interplay between HIV-1 and Host Genetic Variation: A Snapshot into Its Impact on AIDS and Therapy Response.

Advances in virology 20120101

Studies on the restriction of murine leukemia viruses by mouse APOBEC3.

PloS one 20120101

Explicit hypoxia targeting with tumor suppression by creating an 'obligate' anaerobic Salmonella Typhimurium strain.

Scientific reports 20120101

Thrombospondin-1 in early flow-related remodeling of mesenteric arteries from young normotensive and spontaneously hypertensive rats.

The open cardiovascular medicine journal 20120101

The 3' splice site of influenza A segment 7 mRNA can exist in two conformations: a pseudoknot and a hairpin.

PloS one 20120101

The G protein coupled receptor 3 is involved in cAMP and cGMP signaling and maintenance of meiotic arrest in porcine oocytes.

PloS one 20120101

Evidence for a functional adrenomedullin signaling pathway in the mouse retina.

Molecular vision 20120101

Maternal diet modulates placenta growth and gene expression in a mouse model of diabetic pregnancy.

PloS one 20120101

Efficiency of purine utilization by Helicobacter pylori: roles for adenosine deaminase and a NupC homolog.

PloS one 20120101

Progression from Sustained BK Viruria to Sustained BK Viremia with Immunosuppression Reduction Is Not Associated with Changes in the Noncoding Control Region of the BK Virus Genome.

Journal of transplantation 20120101

Voltammetric investigation of DNA damage induced by nitrofurazone and short-lived nitro-radicals with the use of an electrochemical DNA biosensor.

Biosensors & bioelectronics 20120101

The Bin3 RNA methyltransferase targets 7SK RNA to control transcription and translation.

Wiley interdisciplinary reviews. RNA 20120101

Remyelination induced by a DNA aptamer in a mouse model of multiple sclerosis.

PloS one 20120101

Analysis of 5'-mononucleotides in infant formula and adult/pediatric nutritional formula by liquid chromatography: First Action 2011.20.

Journal of AOAC International 20120101

HILIC-MS/MS method for the quantitation of nucleotides in infant formula and adult nutritional formula: First Action 2011.21.

Journal of AOAC International 20120101

Presynaptic selectivity of a ligand for serotonin 1A receptors revealed by in vivo PET assays of rat brain.

PloS one 20120101

Associations between purine metabolites and clinical symptoms in schizophrenia.

PloS one 20120101

Targeting phosphodiesterases in anti-platelet therapy.

Handbook of experimental pharmacology 20120101

Quantitative and chemical fingerprint analysis for the quality evaluation of Isatis indigotica based on ultra-performance liquid chromatography with photodiode array detector combined with chemometric methods.

International journal of molecular sciences 20120101

Enzymatically active and inactive phosphodiesterases and diguanylate cyclases are involved in regulation of Motility or sessility in Escherichia coli CFT073.

mBio 20120101

2-Methylwyosine, a nucleoside with restricted anti conformation in the east region enforced by nucleobase moiety modification: synthesis and conformational analysis by NMR and molecular dynamics.

Nucleosides, nucleotides & nucleic acids 20120101

A possible explanation for anemia in patients treated with mycophenolic acid.

Transplantation 20111227

The differential modulation of USP activity by internal regulatory domains, interactors and eight ubiquitin chain types.

Chemistry & biology 20111223

Phosphorodiamidates as a promising new phosphate prodrug motif for antiviral drug discovery: application to anti-HCV agents.

Journal of medicinal chemistry 20111222

XPD and hOGG1 gene polymorphisms in reperfusion oxidative stress.

Genetics and molecular research : GMR 20111219

Development and in vitro characterization of a novel bifunctional μ-agonist/δ-antagonist opioid tetrapeptide.

ACS chemical biology 20111216

C(5) modified uracil derivatives showing antiproliferative and erythroid differentiation inducing activities on human chronic myelogenous leukemia K562 cells.

European journal of pharmacology 20111215

CCR2 receptor antagonists: optimization of biaryl sulfonamides to increase activity in whole blood.

Bioorganic & medicinal chemistry letters 20111215

Identifying guanosine self assembly at natural isotopic abundance by high-resolution 1H and 13C solid-state NMR spectroscopy.

Journal of the American Chemical Society 20111214

Pyruvate is the source of the two carbons that are required for formation of the imidazoline ring of 4-demethylwyosine.

Biochemistry 20111213

Discovery of aminobenzyloxyarylamides as κ opioid receptor selective antagonists: application to preclinical development of a κ opioid receptor antagonist receptor occupancy tracer.

Journal of medicinal chemistry 20111208

Involvement of NOX1/NADPH oxidase in morphine-induced analgesia and tolerance.

The Journal of neuroscience : the official journal of the Society for Neuroscience 20111207

DNA-catalyzed reductive amination.

Angewandte Chemie (International ed. in English) 20111202

Design, synthesis and characterisation of guanosine-based amphiphiles.

Chemistry (Weinheim an der Bergstrasse, Germany) 20111202

Role of gonadal hormones on mu-opioid-stimulated [³⁵S]GTPγS binding and morphine-mediated antinociception in male and female Sprague-Dawley rats.

Psychopharmacology 20111201

Effect of high pressure processing on the level of some purines and pyrimidines nucleosides and bases in dry cured and cooked ham.

Meat science 20111201

Possible biological markers of the time of processing of dry-cured ham.

Meat science 20111201

Conformational preferences of modified nucleoside N(2)-methylguanosine (m(2)G) and its derivative N(2), N(2)-dimethylguanosine (m(2)(2)G) occur at 26th position (hinge region) in tRNA.

Cell biochemistry and biophysics 20111201

Identification of the core sequence elements in Penaeus stylirostris densovirus promoters.

Virus genes 20111201

tRNA structural and functional changes induced by oxidative stress.

Cellular and molecular life sciences : CMLS 20111201

Effect of ΔFosB overexpression on opioid and cannabinoid receptor-mediated signaling in the nucleus accumbens.

Neuropharmacology 20111201

The 8-hydroxydeoxyguanosine concentrations according to hormone therapy and S326C polymorphism of OGG1 gene in postmenopausal women.

Molecular genetics and metabolism 20111201

Essential role for orbitofrontal serotonin 1B receptors in obsessive-compulsive disorder-like behavior and serotonin reuptake inhibitor response in mice.

Biological psychiatry 20111201

Urinary markers of nucleic acid oxidation and long-term mortality of newly diagnosed type 2 diabetic patients.

Diabetes care 20111201

Modulation of dADAR-dependent RNA editing by the Drosophila fragile X mental retardation protein.

Nature neuroscience 20111201

Asymmetry of (13)C labeled 3-pyruvate affords improved site specific labeling of RNA for NMR spectroscopy.

Journal of biomolecular NMR 20111201

Purine nucleoside phosphorylase deficiency: a mutation update.

Nucleosides, nucleotides & nucleic acids 20111201

Overexpression of dedicator of cytokinesis I (Dock180) in ovarian cancer correlated with aggressive phenotype and poor patient survival.

Histopathology 20111201

Glut1 deficiency syndrome and erythrocyte glucose uptake assay.

Annals of neurology 20111201

Dual or triple activation of TLR7, TLR8, and/or TLR9 by single-stranded oligoribonucleotides.

Nucleic acid therapeutics 20111201

The RNA silencing enzyme RNA polymerase v is required for plant immunity.

PLoS genetics 20111201

Treatment of myasthenia gravis based on its immunopathogenesis.

Journal of clinical neurology (Seoul, Korea) 20111201

Anti-adipogenic activity of Cordyceps militaris in 3T3-L1 cells.

Natural product communications 20111201

The Protective Effect of Black Ginseng Against Transient Focal Ischemia-induced Neuronal Damage in Rats.

The Korean journal of physiology & pharmacology : official journal of the Korean Physiological Society and the Korean Society of Pharmacology 20111201

Treatment of recalcitrant herpes simplex virus with topical imiquimod.

Cutis 20111201

[Study on HPLC fingerprint chromatograms of Arisaematis Rhizoma].

Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20111201

cGMP Signaling, Phosphodiesterases and Major Depressive Disorder.

Current neuropharmacology 20111201

A novel form of low-frequency hippocampal mossy fiber plasticity induced by bimodal mGlu1 receptor signaling.

The Journal of neuroscience : the official journal of the Society for Neuroscience 20111123

A metabolic profiling analysis of symptomatic gout in human serum and urine using high performance liquid chromatography-diode array detector technique.

Clinica chimica acta; international journal of clinical chemistry 20111120

RAM/Fam103a1 is required for mRNA cap methylation.

Molecular cell 20111118

An active-site guanine participates in glmS ribozyme catalysis in its protonated state.

Journal of the American Chemical Society 20111116

Solution structure of the state 1 conformer of GTP-bound H-Ras protein and distinct dynamic properties between the state 1 and state 2 conformers.

The Journal of biological chemistry 20111111

Synthesis of 2'-N-methylamino-2'-deoxyguanosine and 2'-N,N-dimethylamino-2'-deoxyguanosine and their incorporation into RNA by phosphoramidite chemistry.

The Journal of organic chemistry 20111104

Modulation of GABA transport by adenosine A1R-A2AR heteromers, which are coupled to both Gs- and G(i/o)-proteins.

The Journal of neuroscience : the official journal of the Society for Neuroscience 20111102

Sequential and opposing alterations of 5-HT(1A) receptor function during withdrawal from chronic morphine.

European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology 20111101

Retron Se72 utilizes a unique strategy of the self-priming initiation of reverse transcription.

Cellular and molecular life sciences : CMLS 20111101

Recombinant WNTs differentially activate β-catenin-dependent and -independent signalling in mouse microglia-like cells.

Acta physiologica (Oxford, England) 20111101

Protein therapy using heme-oxygenase-1 fused to a polyarginine transduction domain attenuates cerebral vasospasm after experimental subarachnoid hemorrhage.

Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 20111101

Transactivation of epidermal growth factor receptor by enhanced levels of endogenous angiotensin II contributes to the overexpression of Giα proteins in vascular smooth muscle cells from SHR.

Cellular signalling 20111101

Adenosine-to-inosine RNA editing meets cancer.

Carcinogenesis 20111101

The clozapine metabolite N-desmethylclozapine displays variable activity in diverse functional assays at human dopamine D₂ and serotonin 5-HT₁A receptors.

European journal of pharmacology 20111101

Sex difference in κ-opioid receptor (KOPR)-mediated behaviors, brain region KOPR level and KOPR-mediated guanosine 5'-O-(3-[35S]thiotriphosphate) binding in the guinea pig.

The Journal of pharmacology and experimental therapeutics 20111101

Differential effects of nociceptin/orphanin FQ (NOP) receptor agonists in acute versus chronic pain: studies with bifunctional NOP/μ receptor agonists in the sciatic nerve ligation chronic pain model in mice.

The Journal of pharmacology and experimental therapeutics 20111101

Pre-ovulatory LH/hCG surge decreases C-type natriuretic peptide secretion by ovarian granulosa cells to promote meiotic resumption of pre-ovulatory oocytes.

Human reproduction (Oxford, England) 20111101

Stability and mismatch discrimination of locked nucleic acid-DNA duplexes.

Biochemistry 20111101

A prophylactic effect of an oligodeoxynucleotide containing a cytidine-guanosine motif against Japanese cedar pollen-induced T-helper type 2 allergic response.

The Journal of asthma : official journal of the Association for the Care of Asthma 20111101

Evidence for macrocyclic lactone anthelmintic resistance in Dirofilaria immitis.

Topics in companion animal medicine 20111101

Simultaneous determination of five nucleosides and nucleobases of Rehmannia glutinosa Libosch. by high performance liquid chromatography.

Yao xue xue bao = Acta pharmaceutica Sinica 20111101

STING is a direct innate immune sensor of cyclic di-GMP.

Nature 20111027

8-(p-CF3-cinnamyl)-modified purine nucleosides as promising fluorescent probes.

Organic & biomolecular chemistry 20111026

Pin1 and WWP2 regulate GluR2 Q/R site RNA editing by ADAR2 with opposing effects.

The EMBO journal 20111019

Structural analysis of the Ras-like G protein MglA and its cognate GAP MglB and implications for bacterial polarity.

The EMBO journal 20111019

Towards multimodal HPLC separations on humic acid-bonded aminopropyl silica: RPLC and LEC behavior.

Talanta 20111015

GTP-dependent binding and nuclear transport of RNA polymerase II by Npa3 protein.

The Journal of biological chemistry 20111014

Protein glycoengineering enabled by the versatile synthesis of aminooxy glycans and the genetically encoded aldehyde tag.

Journal of the American Chemical Society 20111012

Structure-function analysis from the outside in: long-range tertiary contacts in RNA exhibit distinct catalytic roles.

Biochemistry 20111011

Molecular targeting of CSN5 in human hepatocellular carcinoma: a mechanism of therapeutic response.

Oncogene 20111006

Synthesis of 2'-deoxy-2'-[18F]fluoro-9-β-D-arabinofuranosylguanine: a novel agent for imaging T-cell activation with PET.

Molecular imaging and biology : MIB : the official publication of the Academy of Molecular Imaging 20111001

The state-of-the-art determination of urinary nucleosides using chromatographic techniques 'hyphenated' with advanced bioinformatic methods.

Analytical and bioanalytical chemistry 20111001

G-quadruplexes: from guanine gels to chemotherapeutics.

Molecular biotechnology 20111001

Guanosine supplementation reduces the antiproliferative and apoptotic effects of the IMPDH inhibitor gnidilatimonoein in K562 cells.

Cell biology international 20111001

Decitabine and suberoylanilide hydroxamic acid (SAHA) inhibit growth of ovarian cancer cell lines and xenografts while inducing expression of imprinted tumor suppressor genes, apoptosis, G2/M arrest, and autophagy.

Cancer 20111001

Anti-platelet therapy: phosphodiesterase inhibitors.

British journal of clinical pharmacology 20111001

Zinc homeostasis and signaling in health and diseases: Zinc signaling.

Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry 20111001

Potentiation of μ-opioid receptor-mediated signaling by ketamine.

Journal of neurochemistry 20111001

Regulation of ingestive behaviors in the rat by GSK1521498, a novel micro-opioid receptor-selective inverse agonist.

The Journal of pharmacology and experimental therapeutics 20111001

Physiological response to membrane protein overexpression in E. coli.

Molecular & cellular proteomics : MCP 20111001

Molecular determinants of PKA-dependent inhibition of TRPC5 channel.

American journal of physiology. Cell physiology 20111001

Triplet-state dynamics of a metalloporphyrin photosensitiser (PtTMPyP4) in the presence of halides and purine mononucleotides.

Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology 20111001

The G protein-coupled cannabinoid-1 (CB1) receptor of mammalian brain: inhibition by phthalate esters in vitro.

Neurochemistry international 20111001

Differential stringent control of Escherichia coli rRNA promoters: effects of ppGpp, DksA and the initiating nucleotides.

Microbiology (Reading, England) 20111001

Neutral loss and precursor ion scan tandem mass spectrometry for study of activated benzopyrene-DNA adducts.

Analytical and bioanalytical chemistry 20111001

Substrate-induced conformational changes in Plasmodium falciparum guanosine monophosphate synthetase.

The FEBS journal 20111001

CART peptide stimulation of G protein-mediated signaling in differentiated PC12 cells: identification of PACAP 6-38 as a CART receptor antagonist.

Neuropeptides 20111001

Pharmacological mechanisms underlying the antinociceptive and tolerance effects of the 6,14-bridged oripavine compound 030418.

Acta pharmacologica Sinica 20111001

Probing DNA interstrand cross-link formation by an oxidized abasic site using nonnative nucleotides.

Bioorganic & medicinal chemistry 20111001

The herpes simplex virus-1 transactivator infected cell protein-4 drives VEGF-A dependent neovascularization.

PLoS pathogens 20111001

Sustained CD8+ T cell memory inflation after infection with a single-cycle cytomegalovirus.

PLoS pathogens 20111001

Identification of widespread ultra-edited human RNAs.

PLoS genetics 20111001

Mycophenolic acid mediated mitochondrial membrane potential transition change lead to T lymphocyte apoptosis.

Journal of the Korean Surgical Society 20111001

Identification of the orphan G protein-coupled receptor GPR31 as a receptor for 12-(S)-hydroxyeicosatetraenoic acid.

The Journal of biological chemistry 20110930

A quantitative study of neuronal nitric oxide synthase expression in laminae I-III of the rat spinal dorsal horn.

Neuroscience 20110929

Identification of ML204, a novel potent antagonist that selectively modulates native TRPC4/C5 ion channels.

The Journal of biological chemistry 20110923

Alkylating potential of α,β-unsaturated compounds.

Organic & biomolecular chemistry 20110921

Circular dichroism and UV-Vis absorption spectroscopic monitoring of production of chiral silver nanoparticles templated by guanosine 5'-monophosphate.

The Analyst 20110921

A prebiotic role for 8-oxoguanosine as a flavin mimic in pyrimidine dimer photorepair.

Journal of the American Chemical Society 20110921

Nucleobase transport by human equilibrative nucleoside transporter 1 (hENT1).

The Journal of biological chemistry 20110916

Role for the membrane receptor guanylyl cyclase-C in attention deficiency and hyperactive behavior.

Science (New York, N.Y.) 20110916

Guanine-induced inhibition of renal Na(+)-ATPase activity: evidence for the involvement of the Gi protein-coupled receptor.

Archives of biochemistry and biophysics 20110915

Identification and quantification of nucleosides and nucleobases in Geosaurus and Leech by hydrophilic-interaction chromatography.

Talanta 20110915

Activation and inhibition of CTP synthase from Trypanosoma brucei, the causative agent of African sleeping sickness.

Bioorganic & medicinal chemistry letters 20110915

Ebola virus entry requires the cholesterol transporter Niemann-Pick C1.

Nature 20110915

Adjuvant effect of cationic liposomes and CpG depends on administration route.

Journal of controlled release : official journal of the Controlled Release Society 20110905

Effect of thioethers on DNA platination by trans-platinum complexes.

Inorganic chemistry 20110905

Administration route and carrier dependent effects on vaccine efficacy: implications for vaccine design.

Journal of controlled release : official journal of the Controlled Release Society 20110905

Identification of a novel Arabidopsis thaliana nitric oxide-binding molecule with guanylate cyclase activity in vitro.

FEBS letters 20110902

Genome-wide evaluation and discovery of vertebrate A-to-I RNA editing sites.

Biochemical and biophysical research communications 20110902

Nitric oxide signaling modulates synaptic transmission during early postnatal development.

Cerebral cortex (New York, N.Y. : 1991) 20110901

Dietary fish oil reduces DNA adduct formation while estradiol upregulates apoptosis in response to DNA damage in the rat colon.

Digestive diseases and sciences 20110901

Functional coupling between metabotropic glutamate receptors and G-proteins in rat cerebral cortex assessed by guanosine-5'-O-(3-[(35)S]thio)triphosphate binding assay.

Basic & clinical pharmacology & toxicology 20110901

Natriuretic peptide receptor-3 underpins the disparate regulation of endothelial and vascular smooth muscle cell proliferation by C-type natriuretic peptide.

British journal of pharmacology 20110901

ER-resident Gi2 protein controls sar1 translocation onto the ER during budding of transport vesicles.

Journal of cellular biochemistry 20110901

A dual acting compound releasing nitric oxide (NO) and ibuprofen, NCX 320, shows significant therapeutic effects in a mouse model of muscular dystrophy.

Pharmacological research 20110901

Characterization of a sphingosine 1-phosphate receptor antagonist prodrug.

The Journal of pharmacology and experimental therapeutics 20110901

Third intracellular loop of glucagon like-peptide-1 receptor is coupled with endogenous mono-ADP-ribosyltransferase - novel type of receptor regulation?

European journal of pharmacology 20110901

Estrogen regulation of the dopamine-activated GIRK channel in pituitary lactotrophs: implications for regulation of prolactin release during the estrous cycle.

American journal of physiology. Regulatory, integrative and comparative physiology 20110901

Neuroprotective effect of guanosine against glutamate-induced cell death in rat hippocampal slices is mediated by the phosphatidylinositol-3 kinase/Akt/ glycogen synthase kinase 3β pathway activation and inducible nitric oxide synthase inhibition.

Journal of neuroscience research 20110901

Validation of the catalytic mechanism of Escherichia coli purine nucleoside phosphorylase by structural and kinetic studies.

Biochimie 20110901

ppGpp in Sinorhizobium meliloti: biosynthesis in response to sudden nutritional downshifts and modulation of the transcriptome.

Molecular microbiology 20110901

Emerging drugs for varicella-zoster virus infections.

Expert opinion on emerging drugs 20110901

Mutagenicity of secondary oxidation products of 8-oxo-7,8-dihydro-2'-deoxyguanosine 5'-triphosphate (8-hydroxy-2'- deoxyguanosine 5'-triphosphate).

Mutation research 20110901

RIC8 is a guanine-nucleotide exchange factor for Galpha subunits that regulates growth and development in Neurospora crassa.

Genetics 20110901

Cyclic GMP induced apoptosis via protein kinase G in oestrogen receptor-positive and -negative breast cancer cell lines.

The FEBS journal 20110901

Signalling by the global regulatory molecule ppGpp in bacteria and chloroplasts of land plants.

Plant biology (Stuttgart, Germany) 20110901

Transfer RNA-mediated regulation of ribosome dynamics during protein synthesis.

Nature structural & molecular biology 20110901

6-Thioguanine inhibition of parathyroid hormone-related protein expression is mediated by GLI2.

Anticancer research 20110901

Influence of nitric oxide on in vitro growth, survival, steroidogenesis, and apoptosis of follicle stimulating hormone stimulated buffalo (Bubalus bubalis) preantral follicles.

Journal of veterinary science 20110901

BrabA.11339.a: anomalous diffraction and ligand binding guide towards the elucidation of the function of a 'putative β-lactamase-like protein' from Brucella melitensis.

Acta crystallographica. Section F, Structural biology and crystallization communications 20110901

Differences between Trypanosoma brucei gambiense groups 1 and 2 in their resistance to killing by trypanolytic factor 1.

PLoS neglected tropical diseases 20110901

[Effects of mycophenolic acid on human bone marrow-derived mesenchymal stem cells in vitro].

Zhejiang da xue xue bao. Yi xue ban = Journal of Zhejiang University. Medical sciences 20110901

Mechanisms and factors that influence high frequency retroviral recombination.

Viruses 20110901

Recombination in eukaryotic single stranded DNA viruses.

Viruses 20110901

Neuropsychiatric systemic lupus erythematosus.

Current neuropharmacology 20110901

Antioxidative caffeoylquinic acids and flavonoids from Hemerocallis fulva flowers.

Journal of agricultural and food chemistry 20110824

Stereoselective synthesis of amides sharing the guanosine 5'-monophosphate scaffold and Umami enhancement studies using human sensory and hT1R1/rT1R3 receptor assays.

Journal of agricultural and food chemistry 20110824

Synthesis and assembling properties of bioorganometallic cyclometalated Au(III) alkynyls bearing guanosine moieties.

Organic & biomolecular chemistry 20110821

Ligand modulation of the Epstein-Barr virus-induced seven-transmembrane receptor EBI2: identification of a potent and efficacious inverse agonist.

The Journal of biological chemistry 20110819

Systemic administration of guanosine promotes functional and histological improvement following an ischemic stroke in rats.

Brain research 20110817

Chronic neuropathic pain in mice reduces μ-opioid receptor-mediated G-protein activity in the thalamus.

Brain research 20110811

shRNA knockdown of guanylate cyclase 2e or cyclic nucleotide gated channel alpha 1 increases photoreceptor survival in a cGMP phosphodiesterase mouse model of retinitis pigmentosa.

Journal of cellular and molecular medicine 20110801

Progesterone signals through membrane progesterone receptors (mPRs) in MDA-MB-468 and mPR-transfected MDA-MB-231 breast cancer cells which lack full-length and N-terminally truncated isoforms of the nuclear progesterone receptor.

Steroids 20110801

Absolute configurations and stability of cyclic guanosine mono-adducts with glyoxal and methylglyoxal.

Chirality 20110801

Internalization of exogenous ADP-ribosylation factor 6 (Arf6) proteins into cells.

Molecular and cellular biochemistry 20110801

Curcumin mediates both dilation and constriction of peripheral arterioles via adrenergic receptors.

The Journal of investigative dermatology 20110801

Agonist-induced desensitization/resensitization of human G protein-coupled receptor 17: a functional cross-talk between purinergic and cysteinyl-leukotriene ligands.

The Journal of pharmacology and experimental therapeutics 20110801

Enhanced production of GDP-L-fucose by overexpression of NADPH regenerator in recombinant Escherichia coli.

Applied microbiology and biotechnology 20110801

Understanding the effect of different assay formats on agonist parameters: a study using the µ-opioid receptor.

Journal of biomolecular screening 20110801

High-throughput fluorescence polarization assay for the enzymatic activity of GTPase-activating protein of ADP-ribosylation factor (ARFGAP).

Journal of biomolecular screening 20110801

Depletion of GTP pool is not the predominant mechanism by which ribavirin exerts its antiviral effect on Lassa virus.

Antiviral research 20110801

Site-specific recognition of guanosine by manganese(III) corroles in DNA non-duplex regions through active oxygen transfer.

Chemistry (Weinheim an der Bergstrasse, Germany) 20110801

Sensitization to MDMA locomotor effects and changes in the functionality of 5-HT(2A) and D₂ receptors in mice.

Behavioural pharmacology 20110801

Quantification of cAMP and cGMP analogs in intact cells: pitfalls in enzyme immunoassays for cyclic nucleotides.

Naunyn-Schmiedeberg's archives of pharmacology 20110801

Enzyme kinetics of the mitochondrial deoxyribonucleoside salvage pathway are not sufficient to support rapid mtDNA replication.

PLoS computational biology 20110801

Epigenetic abnormalities in myeloproliferative neoplasms: a target for novel therapeutic strategies.

Clinical epigenetics 20110801

Benchmarking AMBER force fields for RNA: comparisons to NMR spectra for single-stranded r(GACC) are improved by revised χ torsions.

The journal of physical chemistry. B 20110728

Cell-type-specific CCK2 receptor signaling underlies the cholecystokinin-mediated selective excitation of hippocampal parvalbumin-positive fast-spiking basket cells.

The Journal of neuroscience : the official journal of the Society for Neuroscience 20110727

Conformational states of ADP ribosylation factor 1 complexed with different guanosine triphosphates as studied by 31P NMR spectroscopy.

Biochemistry 20110726

Hydrogen-bond-directed giant unilamellar vesicles of guanosine derivative: preparation, properties, and fusion.

Langmuir : the ACS journal of surfaces and colloids 20110719

The clinical potential of the acyclic (and cyclic) nucleoside phosphonates: the magic of the phosphonate bond.

Biochemical pharmacology 20110715

Activation of κ opioid receptors increases intrinsic excitability of dentate gyrus granule cells.

The Journal of physiology 20110715

The melatonergic agonist and clinically active antidepressant, agomelatine, is a neutral antagonist at 5-HT(2C) receptors.

The international journal of neuropsychopharmacology 20110701

Influence of irradiation on in vitro red-blood-cell (RBC) storage variables of leucoreduced RBCs in additive solution PAGGS-M.

Vox sanguinis 20110701

cGMP-dependent ABA-induced stomatal closure in the ABA-insensitive Arabidopsis mutant abi1-1.

The New phytologist 20110701

Measuring thermodynamic details of DNA hybridization using fluorescence.

Biopolymers 20110701

Role of SRC family kinase in extracellular renal cyclic guanosine 3',5'-monophosphate- and pressure-induced natriuresis.

Hypertension (Dallas, Tex. : 1979) 20110701

A three-dimensional pharmacophore model for IMPDH inhibitors.

Chemical biology & drug design 20110701

Multiple roles for Plasmodium berghei phosphoinositide-specific phospholipase C in regulating gametocyte activation and differentiation.

Cellular microbiology 20110701

The bulky N6 substituent of cabergoline is responsible for agonism of this drug at 5-hydroxytryptamine 5-HT2A and 5-HT2B receptors and thus is a determinant of valvular heart disease.

The Journal of pharmacology and experimental therapeutics 20110701

A selective adenosine sensor derived from a triplex DNA aptamer.

Analytical and bioanalytical chemistry 20110701

The L-kynurenine signalling pathway in trigeminal pain processing: a potential therapeutic target in migraine?

Cephalalgia : an international journal of headache 20110701

Arabidopsis thaliana nucleosidase mutants provide new insights into nucleoside degradation.

The New phytologist 20110701

Study of retention behaviour and mass spectrometry compatibility in zwitterionic hydrophilic interaction chromatography for the separation of modified nucleosides and nucleobases.

Journal of chromatography. A 20110701

Oxidative damage in multiple sclerosis lesions.

Brain : a journal of neurology 20110701

Paradoxical facilitation of exocytosis by inhibition of L-type calcium channels of bovine chromaffin cells.

Biochemical and biophysical research communications 20110701

Synaptic transmission from horizontal cells to cones is impaired by loss of connexin hemichannels.

PLoS biology 20110701

Complete genome sequence of Treponema succinifaciens type strain (6091).

Standards in genomic sciences 20110701

[Characterization of the Rela/SpoT homologue slr1325 (syn-rsh) of the cyanobacterium Synechocystis sp. PCC6803].

Wei sheng wu xue bao = Acta microbiologica Sinica 20110701

Selective activation of Akt1 by mammalian target of rapamycin complex 2 regulates cancer cell migration, invasion, and metastasis.

Oncogene 20110630

Nucleobase and ribose modifications control immunostimulation by a microRNA-122-mimetic RNA.

Journal of the American Chemical Society 20110622

The design and use of a simple System Suitability Test Mix for generic reverse phase high performance liquid chromatography-mass spectrometry systems and the implications for automated system monitoring using global software tracking.

Journal of chromatography. A 20110610

Calpain chronicle--an enzyme family under multidisciplinary characterization.

Proceedings of the Japan Academy. Series B, Physical and biological sciences 20110610

Metabolomic analysis characterizes tissue specific indomethacin-induced metabolic perturbations of rats.

The Analyst 20110607

Evidence for the existence of a specific g protein-coupled receptor activated by guanosine.

ChemMedChem 20110606

Ric-8B is a GTP-dependent G protein alphas guanine nucleotide exchange factor.

The Journal of biological chemistry 20110603

Guanosine is neuroprotective against oxygen/glucose deprivation in hippocampal slices via large conductance Ca²+-activated K+ channels, phosphatidilinositol-3 kinase/protein kinase B pathway activation and glutamate uptake.

Neuroscience 20110602

Protein cysteine S-guanylation and electrophilic signal transduction by endogenous nitro-nucleotides.

Amino acids 20110601

Quantification of hormone sensitive lipase phosphorylation and colocalization with lipid droplets in murine 3T3L1 and human subcutaneous adipocytes via automated digital microscopy and high-content analysis.

Assay and drug development technologies 20110601

Contribution of Rho-kinase to membrane excitability of murine colonic smooth muscle.

British journal of pharmacology 20110601

Synthesis of GDP-mannose using coupling fermentation of recombinant Escherichia coli.

Biotechnology letters 20110601

Genetic ablation of delta opioid receptors in nociceptive sensory neurons increases chronic pain and abolishes opioid analgesia.

Pain 20110601

Genetic and environmental influences on oxidative damage assessed in elderly Danish twins.

Free radical biology & medicine 20110601

Genetic polymorphisms of the beta2-adrenergic receptor relate to guanosine protein-coupled stimulator receptor dysfunction in fibromyalgia syndrome.

The Journal of rheumatology 20110601

Role of the all1549 (ana-rsh) gene, a relA/spoT homolog, of the Cyanobacterium Anabaena sp. PCC7120.

Current microbiology 20110601

The dksA promoter is negatively feedback regulated by DksA and ppGpp.

Molecular microbiology 20110601

Ras signaling pathways mediate NGF-induced enhancement of excitability of small-diameter capsaicin-sensitive sensory neurons from wildtype but not Nf1+/- mice.

Neuroscience letters 20110601

Activation of cryptic aminoglycoside resistance in Salmonella enterica.

Molecular microbiology 20110601

Ocular neuroprotection by siRNA targeting caspase-2.

Cell death & disease 20110601

Chiral selectivity of guanosine media in capillary electrophoresis.

Electrophoresis 20110601

The N-terminus of the RNA polymerase from infectious pancreatic necrosis virus is the determinant of genome attachment.

PLoS pathogens 20110601

Biochemical aspects of nitric oxide synthase feedback regulation by nitric oxide.

Interdisciplinary toxicology 20110601

Retinitis pigmentosa: genes and disease mechanisms.

Current genomics 20110601

Free energy simulations of a GTPase: GTP and GDP binding to archaeal initiation factor 2.

The journal of physical chemistry. B 20110526

Tightening of active site interactions en route to the transition state revealed by single-atom substitution in the guanosine-binding site of the Tetrahymena group I ribozyme.

Journal of the American Chemical Society 20110525

Ultrafast photoinduced electron transfer between tetramethylrhodamine and guanosine in aqueous solution.

The journal of physical chemistry. B 20110519

Circular dichroism study of supramolecular assemblies of guanosine 5'-monophosphate.

The journal of physical chemistry. B 20110519

Strand invasion of mixed-sequence, double-helical B-DNA by γ-peptide nucleic acids containing G-clamp nucleobases under physiological conditions.

Biochemistry 20110517

Extracellular nucleotide derivatives protect cardiomyocytes against hypoxic stress.

Biochemical pharmacology 20110515

Chirality delivery from a chiral copper(II) nucleotide complex molecule to its supramolecular architecture.

Dalton transactions (Cambridge, England : 2003) 20110514

Dynamics and couplings of N-H stretching excitations of guanosine-cytidine base pairs in solution.

The journal of physical chemistry. B 20110512

Pin-point chemical modification of RNA with diverse molecules through the functionality transfer reaction and the copper-catalyzed azide-alkyne cycloaddition reaction.

Chemical communications (Cambridge, England) 20110507

Radical-based alkylation of guanine derivatives in aqueous medium.

Organic & biomolecular chemistry 20110507

Cloning and characterization of purine nucleoside phosphorylase in Escherichia coli and subsequent ribavirin biosynthesis using immobilized recombinant cells.

Enzyme and microbial technology 20110506

Photophysical properties of Atto655 dye in the presence of guanosine and tryptophan in aqueous solution.

The journal of physical chemistry. B 20110505

Dehydroascorbic acid adducts of guanosine residues: possible biological implications.

Chembiochem : a European journal of chemical biology 20110502

Intradermal cytosine-phosphate-guanosine treatment reduces lung inflammation but induces IFN-γ-mediated airway hyperreactivity in a murine model of natural rubber latex allergy.

American journal of respiratory cell and molecular biology 20110501

Molecular recognition of the antiretroviral drug abacavir: towards the development of a novel carbazole-based fluorosensor.

Journal of fluorescence 20110501

Mycophenolate mofetil impairs transduction of single-stranded adeno-associated viral vectors.

Human gene therapy 20110501

Long-term diabetic complications may be ameliorated by targeting Rho kinase.

Diabetes/metabolism research and reviews 20110501

Fluorescent and colorimetric chemosensors for detection of nucleotides, FAD and NADH: highlighted research during 2004-2010.

Chemical Society reviews 20110501

The selective sphingosine 1-phosphate receptor 1 agonist ponesimod protects against lymphocyte-mediated tissue inflammation.

The Journal of pharmacology and experimental therapeutics 20110501

Role of nucleoside transporters SLC28A2/3 and SLC29A1/2 genetics in ribavirin therapy: protection against anemia in patients with chronic hepatitis C.

Pharmacogenetics and genomics 20110501

Engineering and visualization of bacteria for targeting infarcted myocardium.

Molecular therapy : the journal of the American Society of Gene Therapy 20110501

Transient RNA-protein interactions in RNA folding.

The FEBS journal 20110501

The role of melatonin in the pathogenesis of adolescent idiopathic scoliosis (AIS).

European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society 20110501

Life without the essential bacterial tRNA Ile2-lysidine synthetase TilS: a case of tRNA gene recruitment in Bacillus subtilis.

Molecular microbiology 20110501

The clinical efficacy of L-DOPA and STN-DBS share a common marker: reduced GABA content in the motor thalamus.

Cell death & disease 20110501

Incorporation of guanosine gels into sieving matrices for length- and sequence-based separation of DNA in capillary electrophoresis.

Electrophoresis 20110501

Identification of hammerhead ribozymes in all domains of life reveals novel structural variations.

PLoS computational biology 20110501

Predicting sites of ADAR editing in double-stranded RNA.

Nature communications 20110501

Involvement of BMPR2 in the protective effect of fluoxetine against monocrotaline-induced endothelial apoptosis in rats.

Canadian journal of physiology and pharmacology 20110501

Genetic reconstruction of protozoan rRNA decoding sites provides a rationale for paromomycin activity against Leishmania and Trypanosoma.

PLoS neglected tropical diseases 20110501

Transplantation of muscle-derived stem cells into the corpus cavernosum restores erectile function in a rat model of cavernous nerve injury.

Korean journal of urology 20110501

Base-selective adsorption of nucleosides to pore-engineered nanocarbon, carbon nanocage.

Journal of nanoscience and nanotechnology 20110501

Lactobacillus adhesion to mucus.

Nutrients 20110501

High expression of NPY receptors in the human testis.

Molecular and cellular endocrinology 20110430

Critical roles of interactions among switch I-preceding residues and between switch II and its neighboring alpha-helix in conformational dynamics of the GTP-bound Ras family small GTPases.

The Journal of biological chemistry 20110429

A G-octamer scaffold via self-assembly of a guanosine-based Au(I) isonitrile complex for Au(I)-Au(I) interaction.

Chemical communications (Cambridge, England) 20110428

8-Oxoguanosine switches modulate the activity of alkylated siRNAs by controlling steric effects in the major versus minor grooves.

Journal of the American Chemical Society 20110427

Ammonia channeling in Plasmodium falciparum GMP synthetase: investigation by NMR spectroscopy and biochemical assays.

Biochemistry 20110426

Release of bioactive volatiles from supramolecular hydrogels: influence of reversible acylhydrazone formation on gel stability and volatile compound evaporation.

Organic & biomolecular chemistry 20110421

Dependence of RelA-mediated (p)ppGpp formation on tRNA identity.

Biochemistry 20110419

Carcinogenic heavy metals, As3+ and Cr6+, increase affinity of nuclear mono-ubiquitinated annexin A1 for DNA containing 8-oxo-guanosine, and promote translesion DNA synthesis.

Toxicology and applied pharmacology 20110415

Sildenafil reverses ABCB1- and ABCG2-mediated chemotherapeutic drug resistance.

Cancer research 20110415

Discovery of a potent and efficacious peptide derivative for δ/μ opioid agonist/neurokinin 1 antagonist activity with a 2',6'-dimethyl-L-tyrosine: in vitro, in vivo, and NMR-based structural studies.

Journal of medicinal chemistry 20110414

Potent and selective inhibitors of the inositol-requiring enzyme 1 endoribonuclease.

The Journal of biological chemistry 20110408

Single atom modification leads to enhanced nucleotide self-assembly: the role of cation bridging.

Chemical communications (Cambridge, England) 20110407

Dynamical insight into Caenorhabditis elegans eIF4E recognition specificity for mono-and trimethylated structures of mRNA 5' cap.

Journal of molecular modeling 20110401

Proper laboratory notebook practices: protecting your intellectual property.

Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology 20110401

Molecular cloning and characterization of a novel ras-related protein (rap2) from Clonorchis sinensis.

Parasitology research 20110401

Nitrergic inhibition of tachykininergic neuro-muscular transmission via cyclic GMP in the hamster ileum.

The Journal of veterinary medical science 20110401

Pharmacological characterization of a nociceptin receptor from zebrafish (Danio rerio).

Journal of molecular endocrinology 20110401

The association between low-grade inflammation, iron status and nucleic acid oxidation in the elderly.

Free radical research 20110401

Mechanism of action of ribavirin in a novel hepatitis C virus replication cell system.

Virus research 20110401

Cannabinoids inhibit insulin receptor signaling in pancreatic β-cells.

Diabetes 20110401

DNA-methylation profiling distinguishes malignant melanomas from benign nevi.

Pigment cell & melanoma research 20110401

A guanosine 3',5'-cyclic monophosphate (cGMP) reporter system based on the G-kinase/CREB/CRE signal transduction pathway.

Biochemical and biophysical research communications 20110401

Simultaneous determination of 5'-monophosphate nucleotides in infant formulas by HPLC-MS.

Journal of chromatographic science 20110401

Profile of nucleotides and nucleosides in Taiwanese human milk.

Pediatrics and neonatology 20110401

Fluctuations in spo0A transcription control rare developmental transitions in Bacillus subtilis.

PLoS genetics 20110401

Changes in Adenosine Deaminase Activity in Patients with Type 2 Diabetes Mellitus and Effect of DPP-4 Inhibitor Treatment on ADA Activity.

Diabetes & metabolism journal 20110401

Excited-state dynamics in 6-thioguanosine from the femtosecond to microsecond time scale.

The journal of physical chemistry. B 20110331

In situ evaluation of anticancer drug methotrexate-DNA interaction using a DNA-electrochemical biosensor and AFM characterization.

Physical chemistry chemical physics : PCCP 20110328

Ganciclovir ophthalmic gel 0.15%: in acute herpetic keratitis (dendritic ulcers).

Drugs 20110326

Selective orthosteric free fatty acid receptor 2 (FFA2) agonists: identification of the structural and chemical requirements for selective activation of FFA2 versus FFA3.

The Journal of biological chemistry 20110325

Adenosine deaminases acting on RNA (ADARs) are both antiviral and proviral.

Virology 20110315

Design, synthesis, pharmacological evaluation, and structure-activity study of novel endomorphin analogues with multiple structural modifications.

Journal of medicinal chemistry 20110310

The structural basis for selective binding of non-methylated CpG islands by the CFP1 CXXC domain.

Nature communications 20110308

Non-surgical stem cell delivery strategies and in vivo cell tracking to injured myocardium.

The international journal of cardiovascular imaging 20110301

Negative cooperativity in binding of muscarinic receptor agonists and GDP as a measure of agonist efficacy.

British journal of pharmacology 20110301

Effects of 8-methylguanine on structure, stability and kinetics of formation of tetramolecular quadruplexes.

Biochimie 20110301

Nucleic acid-based fluorescent probes and their analytical potential.

Analytical and bioanalytical chemistry 20110301

No shot in the dark: myxozoans chemically detect fresh fish.

International journal for parasitology 20110301

Gi/o-coupled receptors compete for signaling to adenylyl cyclase in SH-SY5Y cells and reduce opioid-mediated cAMP overshoot.

Molecular pharmacology 20110301

Advances in mass spectrometry-based post-column bioaffinity profiling of mixtures.

Analytical and bioanalytical chemistry 20110301

THRX-198321 is a bifunctional muscarinic receptor antagonist and beta2-adrenoceptor agonist (MABA) that binds in a bimodal and multivalent manner.

Molecular pharmacology 20110301

Microdomain-forming proteins and the role of the reggies/flotillins during axon regeneration in zebrafish.

Biochimica et biophysica acta 20110301

Lower oxidative DNA damage despite greater ROS production in muscles from rats selectively bred for high running capacity.

American journal of physiology. Regulatory, integrative and comparative physiology 20110301

Modulation by endogenously released ATP and opioids of chromaffin cell calcium channels in mouse adrenal slices.

American journal of physiology. Cell physiology 20110301

Active site mapping and substrate specificity of bacterial Hen1, a manganese-dependent 3' terminal RNA ribose 2'O-methyltransferase.

RNA (New York, N.Y.) 20110301

Inhibition of intestinal polyp formation by pitavastatin, a HMG-CoA reductase inhibitor.

Cancer prevention research (Philadelphia, Pa.) 20110301

The folylpolyglutamate synthetase plastidial isoform is required for postembryonic root development in Arabidopsis.

Plant physiology 20110301

Decreased cGMP level contributes to increased contraction in arteries from hypertensive rats: role of phosphodiesterase 1.

Hypertension (Dallas, Tex. : 1979) 20110301

Involvement of the lateral amygdala in the antiallodynic and reinforcing effects of heroin in rats after peripheral nerve injury.

Anesthesiology 20110301

Fluoride-cleavable, fluorescently labelled reversible terminators: synthesis and use in primer extension.

Chemistry (Weinheim an der Bergstrasse, Germany) 20110301

Identification of dihalogenated proteins in rat intestinal mucosa injured by indomethacin.

Journal of clinical biochemistry and nutrition 20110301

Viral genome segmentation can result from a trade-off between genetic content and particle stability.

PLoS genetics 20110301

Consensus-phenotype integration of transcriptomic and metabolomic data implies a role for metabolism in the chemosensitivity of tumour cells.

PLoS computational biology 20110301

[Simultaneous determination of seven nucleosides and nucleobases in aqueous extracts of Fritillaria taipaiensis by HPLC-DAD].

Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20110301

Genetic and epigenetic alterations in pancreatic carcinogenesis.

Current genomics 20110301

Brown spider (Loxosceles genus) venom toxins: tools for biological purposes.

Toxins 20110301

Dynamics of corticosteroid receptors: lessons from live cell imaging.

Acta histochemica et cytochemica 20110226

Synthesis and pharmacological activities of 6-glycine substituted 14-phenylpropoxymorphinans, a novel class of opioids with high opioid receptor affinities and antinociceptive potencies.

Journal of medicinal chemistry 20110224

Probes for narcotic receptor mediated phenomena. 41. Unusual inverse μ-agonists and potent μ-opioid antagonists by modification of the N-substituent in enantiomeric 5-(3-hydroxyphenyl)morphans.

Journal of medicinal chemistry 20110224

Determination of the nucleosides and nucleobases in Tuber samples by dispersive solid-phase extraction combined with liquid chromatography-mass spectrometry.

Analytica chimica acta 20110221

Design and synthesis of highly solvatochromic fluorescent 2'-deoxyguanosine and 2'-deoxyadenosine analogs.

Bioorganic & medicinal chemistry letters 20110215

The muscarinic M(4) receptor is the functionally predominant subtype in rat and mouse striatum as demonstrated using [(35)S] GTPγS binding.

European journal of pharmacology 20110210

Residual effects of focal brain ischaemia upon cannabinoid CB(1) receptor density and functionality in female rats.

Brain research 20110210

Ionization of purine tautomers in nucleobases, nucleosides, and nucleotides: from the gas phase to the aqueous environment.

The journal of physical chemistry. B 20110210

Few constraints limit the design of quinone methide-oligonucleotide self-adducts for directing DNA alkylation.

Chemical communications (Cambridge, England) 20110207

Large ring polymers align FtsZ polymers for normal septum formation.

The EMBO journal 20110202

First report of GLUT1 deficiency syndrome in Chinese patients with novel and hot spot mutations in SLC2A1 gene.

Brain & development 20110201

A phase I study of OSI-461 in combination with mitoxantrone in patients with advanced solid tumors potentially responsive to mitoxantrone.

Cancer chemotherapy and pharmacology 20110201

Deletion of fucose residues in plant N-glycans by repression of the GDP-mannose 4,6-dehydratase gene using virus-induced gene silencing and RNA interference.

Plant biotechnology journal 20110201

Mycophenolic acid inhibits natural killer cell proliferation and cytotoxic function: a possible disadvantage of including mycophenolate mofetil in the graft-versus-host disease prophylaxis regimen.

Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation 20110201

Genetic, biochemical, and environmental factors associated with pregnancy outcomes in newborns from the Czech Republic.

Environmental health perspectives 20110201

Meeting report: Guanosines and quadruplexes (London, September 15-17, 2010).

Biochimie 20110201

Txe, an endoribonuclease of the enterococcal Axe-Txe toxin-antitoxin system, cleaves mRNA and inhibits protein synthesis.

Microbiology (Reading, England) 20110201

Differential effects of nitric oxide on blood-brain barrier integrity and cerebral blood flow in intracerebral C6 gliomas.

Neuro-oncology 20110201

Acycloguanosyl 5'-thymidyltriphosphate, a thymidine analogue prodrug activated by telomerase, reduces pancreatic tumor growth in mice.

Gastroenterology 20110201

The hydrolysis of striatal adenine- and guanine-based purines in a 6-hydroxydopamine rat model of Parkinson's disease.

Neurochemical research 20110201

Statin therapy in metabolic syndrome and hypertension post-JUPITER: what is the value of CRP?

Current atherosclerosis reports 20110201

An assay for RNA oxidation induced abasic sites using the Aldehyde Reactive Probe.

Free radical research 20110201

Advancing our understanding of functional genome organisation through studies in the fission yeast.

Current genetics 20110201

Levels of Gsα(short and long), Gα(olf) and Gβ(common) subunits, and calcium-sensitive adenylyl cyclase isoforms (1, 5/6, 8) in post-mortem human brain caudate and cortical membranes: comparison with rat brain membranes and potential stoichiometric relationships.

Neurochemistry international 20110201

Succinate independently stimulates full platelet activation via cAMP and phosphoinositide 3-kinase-β signaling.

Journal of thrombosis and haemostasis : JTH 20110201

Metamorphosis of subarachnoid hemorrhage research: from delayed vasospasm to early brain injury.

Molecular neurobiology 20110201

Identification of 17,20β,21-trihydroxy-4-pregnen-3-one (20β-S) receptor binding and membrane progestin receptor alpha on southern flounder sperm (Paralichthys lethostigma) and their likely role in 20β-S stimulation of sperm hypermotility.

General and comparative endocrinology 20110201

Development of infectious transcripts from full-length and GFP-tagged cDNA clones of Pepper mottle virus and stable systemic expression of GFP in tobacco and pepper.

Virus research 20110201

Yet another nucleoside analog for pancreatic cancer.

Gastroenterology 20110201

Angiotensin AT₂ receptor stimulation inhibits early renal inflammation in renovascular hypertension.

Hypertension (Dallas, Tex. : 1979) 20110201

Structural basis for c-di-GMP-mediated inside-out signaling controlling periplasmic proteolysis.

PLoS biology 20110201

In vitro assessment of the agonist properties of the novel 5-HT1A receptor ligand, CUMI-101 (MMP), in rat brain tissue.

Nuclear medicine and biology 20110201

Conformational changes in quadruplex oligonucleotide structures probed by Raman spectroscopy.

Biomedical optics express 20110201

Interrogation of a Sonogashira cross-coupling of 8-bromoguanosine with phenylacetylene on amberlite: evidence for Pd/Cu ion binding and propagation of Pd/Cu nanoparticles.

Nucleosides, nucleotides & nucleic acids 20110201

Genetic components of stringent response in Vibrio cholerae.

The Indian journal of medical research 20110201

Cytoskeletal dynamics: concepts in measles virus replication and immunomodulation.

Viruses 20110201

AKR1B7 is induced by the farnesoid X receptor and metabolizes bile acids.

The Journal of biological chemistry 20110128

Purification of heterotrimeric G protein alpha subunits by GST-Ric-8 association: primary characterization of purified G alpha(olf).

The Journal of biological chemistry 20110128

Ethanol extract of seeds of Oenothera odorata induces vasorelaxation via endothelium-dependent NO-cGMP signaling through activation of Akt-eNOS-sGC pathway.

Journal of ethnopharmacology 20110127

Systematic studies on the chemical structure and umami enhancing activity of Maillard-modified guanosine 5'-monophosphates.

Journal of agricultural and food chemistry 20110126

Structural and pharmacological analysis of O-2050, a putative neutral cannabinoid CB(1) receptor antagonist.

European journal of pharmacology 20110125

Oxidative damage is present in the fatal brain edema of diabetic ketoacidosis.

Brain research 20110119

Activation of the melanocortin-4 receptor causes enhanced excitation in presympathetic paraventricular neurons in obese Zucker rats.

Regulatory peptides 20110117

Highly sensitive electrochemiluminescent biosensor for adenosine based on structure-switching of aptamer.

Analytica chimica acta 20110117

Isolation of adenosine, iso-sinensetin and dimethylguanosine with antioxidant and HIV-1 protease inhibiting activities from fruiting bodies of Cordyceps militaris.

Phytomedicine : international journal of phytotherapy and phytopharmacology 20110115

Controlled synthesis of Pt nanoparticles array through electroreduction of cisplatin bound at nucleobases terminated surface and application into H2O2 sensing.

Biosensors & bioelectronics 20110115

Reversible organogels triggered by dynamic K+ binding and release.

Journal of colloid and interface science 20110115

Reference ranges of urinary biomarkers of oxidized guanine in (2'-deoxy)ribonucleotides and nucleic acids.

Free radical biology & medicine 20110115

Regulatory effects of ribosomal S6 kinase 1 (RSK1) in IFNλ signaling.

The Journal of biological chemistry 20110114

Organometallic anticancer compounds.

Journal of medicinal chemistry 20110113

Intracellular cAMP assay and Eu-GTP-γS binding studies of chimeric opioid peptide YFa.

European journal of pharmacology 20110110

Can guanine-based purines be considered modulators of intestinal motility in rodents?

European journal of pharmacology 20110110

Defining a process operating window for the synthesis of 5-methyluridine by transglycosylation of guanosine and thymine.

Journal of biotechnology 20110110

Design and synthesis of α-carboxy phosphononucleosides.

The Journal of organic chemistry 20110107

Mice with AS160/TBC1D4-Thr649Ala knockin mutation are glucose intolerant with reduced insulin sensitivity and altered GLUT4 trafficking.

Cell metabolism 20110105

S-Petasin, the Main Sesquiterpene of Petasites formosanus, Inhibits Phosphodiesterase Activity and Suppresses Ovalbumin-Induced Airway Hyperresponsiveness.

Evidence-based complementary and alternative medicine : eCAM 20110101

Decreased GABAA and GABAB receptor functional activity in cannabinoid CB1 receptor knockout mice.

Journal of psychopharmacology (Oxford, England) 20110101

Competitive interaction of 5-HT(1A) receptors with G-protein subtypes in CHO cells demonstrated by RNA interference.

Cellular signalling 20110101

A novel approach for stress-induced gastritis based on paradoxical anti-oxidative and anti-inflammatory action of exogenous 8-hydroxydeoxyguanosine.

Biochemical pharmacology 20110101

Phosphorylation of antiviral and endogenous nucleotides to di- and triphosphates by guanosine monophosphate kinase.

Biochemical pharmacology 20110101

Crosstalk between VEGFR2 and muscarinic receptors regulates the mTOR pathway in serum starved SK-N-SH human neuroblastoma cells.

Cellular signalling 20110101

Reactivity of mucohalic acids in water.

Water research 20110101

Changes in tear protein profile in patients with conjunctivochalasis.

Cornea 20110101

Exercise reduces oxidative stress but does not alleviate hyperinsulinemia or renal dopamine D1 receptor dysfunction in obese rats.

American journal of physiology. Renal physiology 20110101

Cyclic GMP kinase I modulates glucagon release from pancreatic α-cells.

Diabetes 20110101

Metabolic engineering and classic selection of the yeast Candida famata (Candida flareri) for construction of strains with enhanced riboflavin production.

Metabolic engineering 20110101

In vivo patch-clamp analysis of dopaminergic antinociceptive actions on substantia gelatinosa neurons in the spinal cord.

Pain 20110101

Pharmacological blockade of dopamine D2 receptors by aripiprazole is not associated with striatal sensitization.

Naunyn-Schmiedeberg's archives of pharmacology 20110101

Parecoxib and its metabolite valdecoxib directly interact with cannabinoid binding sites in CB1-expressing HEK 293 cells and rat brain tissue.

Neurochemistry international 20110101

Sensitive and selective fluorescence detection of guanosine nucleotides by nanoparticles conjugated with a naphthyridine receptor.

Analytical and bioanalytical chemistry 20110101

Antiviral therapy of CMV disease in children.

Advances in experimental medicine and biology 20110101

Millimolar Mn2+ influences agonist binding to 5-HT1A receptors by inhibiting guanosine nucleotide binding to receptor-coupled G-proteins.

Neurotoxicology 20110101

The role of system-specific molecular chaperones in the maturation of molybdoenzymes in bacteria.

Biochemistry research international 20110101

Purine nucleoside phosphorylase from Schistosoma mansoni in complex with ribose-1-phosphate.

Journal of synchrotron radiation 20110101

Tautomerization in gas-phase ion chemistry of isomeric C-8 deoxyguanosine adducts from phenol-induced DNA damage.

Journal of mass spectrometry : JMS 20110101

The Role of RUNX2 in Osteosarcoma Oncogenesis.

Sarcoma 20110101

Evaluation of overnight hold of whole blood at room temperature before component processing: effect of red blood cell (RBC) additive solutions on in vitro RBC measures.

Transfusion 20110101

Effect of additive solutions on red blood cell (RBC) membrane properties of stored RBCs prepared from whole blood held for 24 hours at room temperature.

Transfusion 20110101

Improving the predictive value of red blood cell storage trials: lessons from the Biomedical Excellence for Safer Transfusion (BEST) Collaborative Trial 41.

Transfusion 20110101

Defining potentially conserved RNA regulons of homologous zinc-finger RNA-binding proteins.

Genome biology 20110101

Patterns and regulation of ribosomal RNA transcription in Borrelia burgdorferi.

BMC microbiology 20110101

Ribavirin potentiates interferon action by augmenting interferon-stimulated gene induction in hepatitis C virus cell culture models.

Hepatology (Baltimore, Md.) 20110101

Identification and characterization of seven new exon 11-associated splice variants of the rat μ opioid receptor gene, OPRM1.

Molecular pain 20110101

Identification of a key amino acid of LuxS involved in AI-2 production in Campylobacter jejuni.

PloS one 20110101

Phenotypic heterogeneity in mycobacterial stringent response.

BMC systems biology 20110101

Common genetic variants of MUTYH are not associated with cutaneous malignant melanoma: application of molecular screening by means of high-resolution melting technique in a pilot case-control study.

The International journal of biological markers 20110101

Sequencing and bioinformatics-based analyses of the microRNA transcriptome in hepatitis B-related hepatocellular carcinoma.

PloS one 20110101

Differential gene expression in liver and small intestine from lactating rats compared to age-matched virgin controls detects increased mRNA of cholesterol biosynthetic genes.

BMC genomics 20110101

Myeloperoxidase-derived oxidation: mechanisms of biological damage and its prevention.

Journal of clinical biochemistry and nutrition 20110101

Nucleotides function as endogenous chemical sensors for oxidative stress signaling.

Journal of clinical biochemistry and nutrition 20110101

PDE 7 inhibitors: new potential drugs for the therapy of spinal cord injury.

PloS one 20110101

Impaired desensitization of a human polymorphic α2B-adrenergic receptor variant enhances its sympatho-inhibitory activity in chromaffin cells.

Cell communication and signaling : CCS 20110101

Protein kinase A type I activates a CRE-element more efficiently than protein kinase A type II regardless of C subunit isoform.

BMC biochemistry 20110101

Diagnostic properties of metabolic perturbations in rheumatoid arthritis.

Arthritis research & therapy 20110101

Cytosolic guanine nucledotide binding deficient form of transglutaminase 2 (R580a) potentiates cell death in oxygen glucose deprivation.

PloS one 20110101

RNA editing by mammalian ADARs.

Advances in genetics 20110101

Phospholipases A₁.

International journal of molecular sciences 20110101

NF-κB potentiates caspase independent hydrogen peroxide induced cell death.

PloS one 20110101

Possible role of the transglutaminases in the pathogenesis of Alzheimer's disease and other neurodegenerative diseases.

International journal of Alzheimer's disease 20110101

Biochemical and physiological characterization of the GTP-binding protein Obg of Mycobacterium tuberculosis.

BMC microbiology 20110101

Deep sequencing of the Camellia sinensis transcriptome revealed candidate genes for major metabolic pathways of tea-specific compounds.

BMC genomics 20110101

Biochemical identification of A-to-I RNA editing sites by the inosine chemical erasing (ICE) method.

Methods in molecular biology (Clifton, N.J.) 20110101

Therapeutic utility of phosphodiesterase type I inhibitors in neurological conditions.

Frontiers in neuroscience 20110101

Toll-like receptor pre-stimulation protects mice against lethal infection with highly pathogenic influenza viruses.

Virology journal 20110101

New implications on genomic adaptation derived from the Helicobacter pylori genome comparison.

PloS one 20110101

Post-transcriptional inhibition of hepatitis C virus replication through small interference RNA.

Virology journal 20110101

The regulatory subunit of PKA-I remains partially structured and undergoes β-aggregation upon thermal denaturation.

PloS one 20110101

Area, age and gender dependence of the nucleoside system in the brain: a review of current literature.

Current topics in medicinal chemistry 20110101

Metabolic network of nucleosides in the brain.

Current topics in medicinal chemistry 20110101

New developments in the treatment of hyperammonemia: emerging use of carglumic acid.

International journal of general medicine 20110101

Plant nucleoside 5'-phosphoramidate hydrolase; simple purification from yellow lupin (Lupinus luteus) seeds and properties of homogeneous enzyme.

Acta biochimica Polonica 20110101

Neurons controlling Aplysia feeding inhibit themselves by continuous NO production.

PloS one 20110101

Structural and spectral characteristics of the cross-linked dimer derived from electrooxidation of cyclic 1,N2-propanoguanosine.

Analytical sciences : the international journal of the Japan Society for Analytical Chemistry 20110101

Modeling antibiotic and cytotoxic effects of the dimeric isoquinoline IQ-143 on metabolism and its regulation in Staphylococcus aureus, Staphylococcus epidermidis and human cells.

Genome biology 20110101

Biochanin a, a phytoestrogenic isoflavone with selective inhibition of phosphodiesterase 4, suppresses ovalbumin-induced airway hyperresponsiveness.

Evidence-based complementary and alternative medicine : eCAM 20110101

Visualization of spatiotemporal energy dynamics of hippocampal neurons by mass spectrometry during a kainate-induced seizure.

PloS one 20110101

The zinc transporter SLC39A14/ZIP14 controls G-protein coupled receptor-mediated signaling required for systemic growth.

PloS one 20110101

Metabolites of purine nucleoside phosphorylase (NP) in serum have the potential to delineate pancreatic adenocarcinoma.

PloS one 20110101

Computational detection and functional analysis of human tissue-specific A-to-I RNA editing.

PloS one 20110101

Statins: cardiovascular risk reduction in percutaneous coronary intervention-basic and clinical evidence of hyperacute use of statins.

International journal of hypertension 20110101

Branched RNA: A New Architecture for RNA Interference.

Journal of nucleic acids 20110101

An overview of HCV molecular biology, replication and immune responses.

Virology journal 20110101

Chronic occupational exposure to hexavalent chromium causes DNA damage in electroplating workers.

BMC public health 20110101

The non-catalytic carboxyl-terminal domain of ARFGAP1 regulates actin cytoskeleton reorganization by antagonizing the activation of Rac1.

PloS one 20110101

Trafficking defect and proteasomal degradation contribute to the phenotype of a novel KCNH2 long QT syndrome mutation.

PloS one 20110101

Peripheral effects of morphine and expression of μ-opioid receptors in the dorsal root ganglia during neuropathic pain: nitric oxide signaling.

Molecular pain 20110101

Efficient silencing of gene expression by an ASON-bulge-DNAzyme complex.

PloS one 20110101

The stimulatory Gα(s) protein is involved in olfactory signal transduction in Drosophila.

PloS one 20110101

1,2-propanediol-trehalose mixture as a potent quantitative real-time PCR enhancer.

BMC biotechnology 20110101

A framework and model system to investigate linear system behavior in Escherichia coli.

Journal of biological engineering 20110101

Isolation and characterization of Ehrlichia chaffeensis RNA polymerase and its use in evaluating p28 outer membrane protein gene promoters.

BMC microbiology 20110101

The antibiotic potential of prokaryotic IMP dehydrogenase inhibitors.

Current medicinal chemistry 20110101

Rab5a regulates surface expression of FcεRI and functional activation in mast cells.

Biological & pharmaceutical bulletin 20110101

Age-dependent maturation of Toll-like receptor-mediated cytokine responses in Gambian infants.

PloS one 20110101

Effect of reverse transcriptase inhibitors on LINE-1 and Ty1 reverse transcriptase activities and on LINE-1 retrotransposition.

BMC biochemistry 20110101

Occurrence and characteristics of group 1 introns found at three different positions within the 28S ribosomal RNA gene of the dematiaceous Phialophora verrucosa: phylogenetic and secondary structural implications.

BMC microbiology 20110101

Specific Silencing of L392V PSEN1 Mutant Allele by RNA Interference.

International journal of Alzheimer's disease 20110101

UMP/CMPK is not the critical enzyme in the metabolism of pyrimidine ribonucleotide and activation of deoxycytidine analogs in human RKO cells.

PloS one 20110101

Genome-wide dynamics of a bacterial response to antibiotics that target the cell envelope.

BMC genomics 20110101

Residue propensities, discrimination and binding site prediction of adenine and guanine phosphates.

BMC biochemistry 20110101

Down-regulation of IRES containing 5'UTR of HCV genotype 3a using siRNAs.

Virology journal 20110101

[Determination of nucleosides in Rhizoma Pinelliae by high performance liquid chromatography].

Se pu = Chinese journal of chromatography 20110101

Antioxidant potential of bitter cumin (Centratherum anthelminticum (L.) Kuntze) seeds in in vitro models.

BMC complementary and alternative medicine 20110101

Inhibition of Hazara nairovirus replication by small interfering RNAs and their combination with ribavirin.

Virology journal 20110101

Synaptically-competent neurons derived from canine embryonic stem cells by lineage selection with EGF and Noggin.

PloS one 20110101

Single-cell time-lapse analysis of depletion of the universally conserved essential protein YgjD.

BMC microbiology 20110101

Population pharmacokinetics and pharmacodynamics of hydroxyurea in sickle cell anemia patients, a basis for optimizing the dosing regimen.

Orphanet journal of rare diseases 20110101

Regulation of colonic ion transport by gasotransmitters.

Biological & pharmaceutical bulletin 20110101

Recent trends in pulmonary arterial hypertension.

Lung India : official organ of Indian Chest Society 20110101

Genetic and Immunological Factors Involved in Natural Resistance to HIV-1 Infection.

The open virology journal 20110101

Intimal hyperplasia in balloon dilated coronary arteries is reduced by local delivery of the NO donor, SIN-1 via a cGMP-dependent pathway.

BMC cardiovascular disorders 20110101

Zeranol down-regulates p53 expression in primary cultured human breast cancer epithelial cells through epigenetic modification.

International journal of molecular sciences 20110101

Mechanisms of estrogens' dose-dependent neuroprotective and neurodamaging effects in experimental models of cerebral ischemia.

International journal of molecular sciences 20110101

Combined 3D-QSAR, molecular docking and molecular dynamics study on derivatives of peptide epoxyketone and tyropeptin-boronic acid as inhibitors against the β5 subunit of human 20S proteasome.

International journal of molecular sciences 20110101

Gβγ subunits inhibit Epac-induced melanoma cell migration.

BMC cancer 20110101

Technologies and approaches to elucidate and model the virulence program of salmonella.

Frontiers in microbiology 20110101

Unexpected accumulation of ncm(5)U and ncm(5)S(2) (U) in a trm9 mutant suggests an additional step in the synthesis of mcm(5)U and mcm(5)S(2)U.

PloS one 20110101

Association between urinary excretion of cortisol and markers of oxidatively damaged DNA and RNA in humans.

PloS one 20110101

Activating effects of chronic variable stress in rats with different exploratory activity: association with dopamine d(1) receptor function in nucleus accumbens.

Neuropsychobiology 20110101

Analysis of the photosynthetic apparatus in transgenic tobacco plants with altered endogenous cytokinin content: a proteomic study.

Proteome science 20110101

Mechanical tuning of molecular machines for nucleotide recognition at the air-water interface.

Nanoscale research letters 20110101

A new drug design targeting the adenosinergic system for Huntington's disease.

PloS one 20110101

Use of specific chemical reagents for detection of modified nucleotides in RNA.

Journal of nucleic acids 20110101

Structural and functional basis for RNA cleavage by Ire1.

BMC biology 20110101

The cycad genotoxin MAM modulates brain cellular pathways involved in neurodegenerative disease and cancer in a DNA damage-linked manner.

PloS one 20110101

Genetic dissection of epidermal growth factor receptor signaling during luteinizing hormone-induced oocyte maturation.

PloS one 20110101

Genomic and protein structural maps of adaptive evolution of human influenza A virus to increased virulence in the mouse.

PloS one 20110101

Nitric Oxide-Soluble Guanylyl Cyclase-Cyclic GMP Signaling in the Striatum: New Targets for the Treatment of Parkinson's Disease?

Frontiers in systems neuroscience 20110101

Pseudomonas aeruginosa: resistance to the max.

Frontiers in microbiology 20110101

Molecular characterization of the uncultivatable hemotropic bacterium Mycoplasma haemofelis.

Veterinary research 20110101

E. coli histidine triad nucleotide binding protein 1 (ecHinT) is a catalytic regulator of D-alanine dehydrogenase (DadA) activity in vivo.

PloS one 20110101

Left ventricular hypertrophy: major risk factor in patients with hypertension: update and practical clinical applications.

International journal of hypertension 20110101

Pleiotropic effects of thyroid hormones: learning from hypothyroidism.

Journal of thyroid research 20110101

Glycyrrhizin as antiviral agent against Hepatitis C Virus.

Journal of translational medicine 20110101

The role of epigenetic alterations in papillary thyroid carcinogenesis.

Journal of thyroid research 20110101

Recent Perspectives on the Relations between Fecal Mutagenicity, Genotoxicity, and Diet.

Frontiers in pharmacology 20110101

Reduced cAMP, Akt activation and p65-c-Rel dimerization: mechanisms involved in the protective effects of mGluR3 agonists in cultured astrocytes.

PloS one 20110101

Evolution of small putative group I introns in the SSU rRNA gene locus of Phialophora species.

BMC research notes 20110101

Resurrection of an ancestral 5S rRNA.

BMC evolutionary biology 20110101

Variables and strategies in development of therapeutic post-transcriptional gene silencing agents.

Journal of ophthalmology 20110101

Gene targeting implicates Cdc42 GTPase in GPVI and non-GPVI mediated platelet filopodia formation, secretion and aggregation.

PloS one 20110101

Mutagenic Tests Confirm That New Acetylacetonate Pt(II) Complexes Induce Apoptosis in Cancer Cells Interacting with Nongenomic Biological Targets.

Metal-based drugs 20110101

Regulation of Inducible Nitric Oxide Synthase (iNOS) and its Potential Role in Insulin Resistance, Diabetes and Heart Failure.

The open cardiovascular medicine journal 20110101

Sequence-dependent fluorescence of cyanine dyes on microarrays.

PloS one 20110101

Interleukin-4 alters early phagosome phenotype by modulating class I PI3K dependent lipid remodeling and protein recruitment.

PloS one 20110101

Open-target sparse sensing of biological agents using DNA microarray.

BMC bioinformatics 20110101

A nuclear magnetic resonance based approach to accurate functional annotation of putative enzymes in the methanogen Methanosarcina acetivorans.

BMC genomics 20110101

Poly-thymidine oligonucleotides mediate activation of murine glial cells primarily through TLR7, not TLR8.

PloS one 20110101

Sulindac sulfide reverses aberrant self-renewal of progenitor cells induced by the AML-associated fusion proteins PML/RARα and PLZF/RARα.

PloS one 20110101

Lethal mutants and truncated selection together solve a paradox of the origin of life.

PloS one 20110101

Polyphosphate--an ancient energy source and active metabolic regulator.

Microbial cell factories 20110101

Therapeutic rescue of misfolded mutants: validation of primary high throughput screens for identification of pharmacoperone drugs.

PloS one 20110101

IPNV with high and low virulence: host immune responses and viral mutations during infection.

Virology journal 20110101

A computational study of elongation factor G (EFG) duplicated genes: diverged nature underlying the innovation on the same structural template.

PloS one 20110101

Evaluation of Abelmoschus moschatus extracts for antioxidant, free radical scavenging, antimicrobial and antiproliferative activities using in vitro assays.

BMC complementary and alternative medicine 20110101

The nucleotide exchange factor Ric-8A is a chaperone for the conformationally dynamic nucleotide-free state of Gαi1.

PloS one 20110101

In vitro and in vivo activity of ribavirin against Andes virus infection.

PloS one 20110101

LRRK2 kinase activity is dependent on LRRK2 GTP binding capacity but independent of LRRK2 GTP binding.

PloS one 20110101

Structural analysis of the essential resuscitation promoting factor YeaZ suggests a mechanism of nucleotide regulation through dimer reorganization.

PloS one 20110101

The kinase inhibitor SFV785 dislocates dengue virus envelope protein from the replication complex and blocks virus assembly.

PloS one 20110101

The RelA/SpoT homolog (RSH) superfamily: distribution and functional evolution of ppGpp synthetases and hydrolases across the tree of life.

PloS one 20110101

G-protein-associated signal transduction processes are restored after postweaning environmental enrichment in Ts65Dn, a Down syndrome mouse model.

Developmental neuroscience 20110101

Amoxapine inhibits delayed outward rectifier K(+) currents in cerebellar granule cells via dopamine receptor and protein kinase A activation.

Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 20110101

Comparison of the 'Ca. Liberibacter asiaticus' genome adapted for an intracellular lifestyle with other members of the Rhizobiales.

PloS one 20110101

Inverse association between methylation of human papillomavirus type 16 DNA and risk of cervical intraepithelial neoplasia grades 2 or 3.

PloS one 20110101

The TLR7/8 ligand resiquimod targets monocyte-derived dendritic cell differentiation via TLR8 and augments functional dendritic cell generation.

Cellular immunology 20110101

Optimisation of surface expression using the AIDA autotransporter.

Microbial cell factories 20110101

Specific interaction of Gαi3 with the Oa1 G-protein coupled receptor controls the size and density of melanosomes in retinal pigment epithelium.

PloS one 20110101

Virtual high-throughput screening identifies mycophenolic acid as a novel RNA capping inhibitor.

PloS one 20110101

Genome of Mycoplasma haemofelis, unraveling its strategies for survival and persistence.

Veterinary research 20110101

IL-4 amplifies the pro-inflammatory effect of adenosine in human mast cells by changing expression levels of adenosine receptors.

PloS one 20110101

Structural insights into the mechanism of protein O-fucosylation.

PloS one 20110101

A truncated form of SpoT, including the ACT domain, inhibits the production of cyclic lipopeptide arthrofactin, and is associated with moderate elevation of guanosine 3',5'-bispyrophosphate level in Pseudomonas sp. MIS38.

Bioscience, biotechnology, and biochemistry 20110101

Evolution under environmental stress at macro- and microscales.

Genome biology and evolution 20110101

Prenatal cocaine exposure increases synaptic localization of a neuronal RasGEF, GRASP-1 via hyperphosphorylation of AMPAR anchoring protein, GRIP.

PloS one 20110101

Neurochemical architecture of the central complex related to its function in the control of grasshopper acoustic communication.

PloS one 20110101

Development of vaccines against burkholderia pseudomallei.

Frontiers in microbiology 20110101

Genomic analysis reveals Lactobacillus sanfranciscensis as stable element in traditional sourdoughs.

Microbial cell factories 20110101

Genome sequences and comparative genomics of two Lactobacillus ruminis strains from the bovine and human intestinal tracts.

Microbial cell factories 20110101

Some aspects of purinergic signaling in the ventricular system of porcine brain.

Acta veterinaria Scandinavica 20110101

Replication of Epstein-Barr virus primary infection in human tonsil tissue explants.

PloS one 20110101

Synthesis of specifically modified oligonucleotides for application in structural and functional analysis of RNA.

Journal of nucleic acids 20110101

Identification of a predominant co-regulation among kinetochore genes, prospective regulatory elements, and association with genomic instability.

PloS one 20110101

The Fur regulon in anaerobically grown Salmonella enterica sv. Typhimurium: identification of new Fur targets.

BMC microbiology 20110101

Primary adenocarcinoma of the stomach in von Recklinghausen's disease with high serum levels of multiple tumor markers: a case report.

Journal of medical case reports 20110101

Differential effects of organic nitrates on arterial diameter among healthy Japanese participants with different mitochondrial aldehyde dehydrogenase 2 genotypes: randomised crossover trial.

BMJ open 20110101

Inverse agonism and its therapeutic significance.

Indian journal of pharmacology 20110101

Reduced nitrate level in individuals with hypertension and diabetes.

Journal of cardiovascular disease research 20110101

Foxf2: a novel locus for anterior segment dysgenesis adjacent to the Foxc1 gene.

PloS one 20110101

Analysis of RNA binding by the dengue virus NS5 RNA capping enzyme.

PloS one 20110101

Research advances on flotillins.

Virology journal 20110101

Inosine-containing RNA is a novel innate immune recognition element and reduces RSV infection.

PloS one 20110101

Cardiovascular and renal effects of carperitide and nesiritide in cardiovascular surgery patients: a systematic review and meta-analysis.

Critical care (London, England) 20110101

Enzymatic properties of Staphylococcus aureus adenosine synthase (AdsA).

BMC biochemistry 20110101

Rapid high yield production of different glycoforms of Ebola virus monoclonal antibody.

PloS one 20110101

UV-sensitive photoreceptor protein OPN5 in humans and mice.

PloS one 20110101

Novel agents for anti-platelet therapy.

Journal of hematology & oncology 20110101

Inhibition of striatal soluble guanylyl cyclase-cGMP signaling reverses basal ganglia dysfunction and akinesia in experimental parkinsonism.

PloS one 20110101

Hesperetin-7,3'-O-dimethylether selectively inhibits phosphodiesterase 4 and effectively suppresses ovalbumin-induced airway hyperresponsiveness with a high therapeutic ratio.

Journal of biomedical science 20110101

8-Modified-2'-deoxyadenosine analogues induce delayed polymerization arrest during HIV-1 reverse transcription.

PloS one 20110101

Use of antimony in the treatment of leishmaniasis: current status and future directions.

Molecular biology international 20110101

Plasmodium falciparum parasites are killed by a transition state analogue of purine nucleoside phosphorylase in a primate animal model.

PloS one 20110101

Serum metabolic profile in multiple sclerosis patients.

Multiple sclerosis international 20110101

Microplate-based platform for combined chromatin and DNA methylation immunoprecipitation assays.

BMC molecular biology 20110101

The role of uridine adenosine tetraphosphate in the vascular system.

Advances in pharmacological sciences 20110101

Bluetongue virus VP1 polymerase activity in vitro: template dependency, dinucleotide priming and cap dependency.

PloS one 20110101

Subtype differences in pre-coupling of muscarinic acetylcholine receptors.

PloS one 20110101

Ribavirin enhances IFN-α signalling and MxA expression: a novel immune modulation mechanism during treatment of HCV.

PloS one 20110101

Retinal degeneration modulates intracellular localization of CDC42 in photoreceptors.

Molecular vision 20110101

Targeting of mitochondria-endoplasmic reticulum by fluorescent macrocyclic compounds.

PloS one 20110101

Non-invasive epigenetic detection of fetal trisomy 21 in first trimester maternal plasma.

PloS one 20110101

A practical approach to T-cell receptor cloning and expression.

PloS one 20110101

Putting the pH into phosphatidic acid signaling.

BMC biology 20110101

Modulation of the host interferon response and ISGylation pathway by B. pertussis filamentous hemagglutinin.

PloS one 20110101

Raloxifene and desmethylarzoxifene block estrogen-induced malignant transformation of human breast epithelial cells.

PloS one 20110101

A knockout mutation of a constitutive GPCR in Tetrahymena decreases both G-protein activity and chemoattraction.

PloS one 20110101

Frontiers of Retrovirology 2011, Amsterdam, The Netherlands, 3-5 October 2011. Meeting Abstracts.

Retrovirology 20110101

Docking studies on novel analogues of 8 methoxy fluoroquinolones against GyrA mutants of Mycobacterium tuberculosis.

BMC structural biology 20110101

Phasevarion mediated epigenetic gene regulation in Helicobacter pylori.

PloS one 20110101

ZipA binds to FtsZ with high affinity and enhances the stability of FtsZ protofilaments.

PloS one 20110101

[Pathogenicity factors of bacteria with glycosylating activity].

Vestnik Rossiiskoi akademii meditsinskikh nauk 20110101

Modulation of phosducin-like protein 3 (PhLP3) levels promotes cytoskeletal remodelling in a MAPK and RhoA-dependent manner.

PloS one 20110101

Flip-flop of phospholipids in proteoliposomes reconstituted from detergent extract of chloroplast membranes: kinetics and phospholipid specificity.

PloS one 20110101

Breaking the cycle: An insight into the role of ERα in eukaryotic cell cycles.

Journal of carcinogenesis 20110101

PPAR-α Agonist Fenofibrate Upregulates Tetrahydrobiopterin Level through Increasing the Expression of Guanosine 5'-Triphosphate Cyclohydrolase-I in Human Umbilical Vein Endothelial Cells.

PPAR research 20110101

Autophagy in inflammatory diseases.

International journal of cell biology 20110101

Rapid S-nitrosylation of actin by NO-generating donors and in inflammatory pain model mice.

Molecular pain 20110101

Inhibitors of alphavirus entry and replication identified with a stable Chikungunya replicon cell line and virus-based assays.

PloS one 20110101

Induction of cytoplasmic rods and rings structures by inhibition of the CTP and GTP synthetic pathway in mammalian cells.

PloS one 20110101

A genomic reappraisal of symbiotic function in the aphid/Buchnera symbiosis: reduced transporter sets and variable membrane organisations.

PloS one 20110101

Structural dynamics of retroviral genome and the packaging.

Frontiers in microbiology 20110101

[Design of Streptomyces nogalater LV65 strains with higher synthesis of nogalamicin using regulatory genes].

Prikladnaia biokhimiia i mikrobiologiia 20110101

Mthfs is an Essential Gene in Mice and a Component of the Purinosome.

Frontiers in genetics 20110101

MicroRNAs as New Characters in the Plot between Epigenetics and Prostate Cancer.

Frontiers in genetics 20110101

Epigenetic Contributions to the Relationship between Cancer and Dietary Intake of Nutrients, Bioactive Food Components, and Environmental Toxicants.

Frontiers in genetics 20110101

Feline and canine coronaviruses: common genetic and pathobiological features.

Advances in virology 20110101

Signal protein-derived peptides as functional probes and regulators of intracellular signaling.

Journal of amino acids 20110101

Developing central nervous system and vulnerability to platinum compounds.

Chemotherapy research and practice 20110101

Plasma cyclic guanosine 3',5'-monophosphate levels: a marker of glutamate-nitric oxide-guanyl cyclase activity?

Journal of opioid management 20110101

Single-molecule sensing electrode embedded in-plane nanopore.

Scientific reports 20110101

The role of nitrogen oxides in human adaptation to hypoxia.

Scientific reports 20110101

Genome-wide essential gene identification in Streptococcus sanguinis.

Scientific reports 20110101

Novel base triples in RNA structures revealed by graph theoretical searching methods.

BMC bioinformatics 20110101

Structure-based and ligand-based virtual screening of novel methyltransferase inhibitors of the dengue virus.

BMC bioinformatics 20110101

[Some inhibitors of purine nucleoside phosphorylase].

Biomeditsinskaia khimiia 20110101

Mining Functional Elements in Messenger RNAs: Overview, Challenges, and Perspectives.

Frontiers in plant science 20110101

Drug discovery opportunities and challenges at g protein coupled receptors for long chain free Fatty acids.

Frontiers in endocrinology 20110101

Defying the stereotype: non-canonical roles of the Peptide hormones guanylin and uroguanylin.

Frontiers in endocrinology 20110101

Cyclic GMP and protein kinase G control a Src-containing mechanosome in osteoblasts.

Science signaling 20101221

Insights into nucleotide recognition by cell division protein FtsZ from a mant-GTP competition assay and molecular dynamics.

Biochemistry 20101214

Ligand-directed trafficking of the δ-opioid receptor in vivo: two paths toward analgesic tolerance.

The Journal of neuroscience : the official journal of the Society for Neuroscience 20101208

Inhibition of microglial and astrocytic inflammatory responses by the immunosuppressant mycophenolate mofetil.

Neuropathology and applied neurobiology 20101201

Reduction of oxidized guanosine by dietary carotenoids: a pulse radiolysis study.

Archives of biochemistry and biophysics 20101201

Adenine, guanine and pyridine nucleotides in blood during physical exercise and restitution in healthy subjects.

European journal of applied physiology 20101201

6S RNA regulation of relA alters ppGpp levels in early stationary phase.

Microbiology (Reading, England) 20101201

The cellular mechanisms underlying the inhibitory effects of isoflurane and sevoflurane on arginine vasopressin-induced vasoconstriction.

Journal of anesthesia 20101201

Electrophysiological analysis of the inhibitory effects of FMRFamide-like peptides on the pacemaker activity of gonadotropin-releasing hormone neurons.

Journal of neurophysiology 20101201

pex5 Mutants that differentially disrupt PTS1 and PTS2 peroxisomal matrix protein import in Arabidopsis.

Plant physiology 20101201

Nucleotide and nucleotide sugar analysis by liquid chromatography-electrospray ionization-mass spectrometry on surface-conditioned porous graphitic carbon.

Analytical chemistry 20101201

Profiles of purine metabolism in leaves and roots of Camellia sinensis seedlings.

Plant & cell physiology 20101201

Brain energy metabolism during experimental neonatal seizures.

Neurochemical research 20101201

A quantitative systems approach reveals dynamic control of tRNA modifications during cellular stress.

PLoS genetics 20101201

Gene expression profiling in rodent models for schizophrenia.

Current neuropharmacology 20101201

Acceptor substrate discrimination in phosphatidyl-myo-inositol mannoside synthesis: structural and mutational analysis of mannosyltransferase Corynebacterium glutamicum PimB'.

The Journal of biological chemistry 20101126

The effect of Δ9-tetrahydrocannabinol on 5-HT3 receptors depends on the current density.

Neuroscience 20101124

ARFGAP2 and ARFGAP3 are essential for COPI coat assembly on the Golgi membrane of living cells.

The Journal of biological chemistry 20101119

2'-O methylation of the viral mRNA cap evades host restriction by IFIT family members.

Nature 20101118

The F-BAR domain of SRGP-1 facilitates cell-cell adhesion during C. elegans morphogenesis.

The Journal of cell biology 20101115

Gas-phase isolation of diethyl guanosine 5'-monophosphate and its conformational assignment.

Physical chemistry chemical physics : PCCP 20101114

Phosphoramidate prodrugs deliver with potency against hepatitis C virus.

ChemMedChem 20101108

Molecular organization and dynamics of the melatonin MT₁ receptor/RGS20/G(i) protein complex reveal asymmetry of receptor dimers for RGS and G(i) coupling.

The EMBO journal 20101103

Enantioselective recognition between polydiacetylene nucleolipid monolayers and complementary oligonucleotides.

Langmuir : the ACS journal of surfaces and colloids 20101102

Quantitative comparison of phosphodiesterase mRNA distribution in human brain and peripheral tissues.

Neuropharmacology 20101101

An improved red blood cell additive solution maintains 2,3-diphosphoglycerate and adenosine triphosphate levels by an enhancing effect on phosphofructokinase activity during cold storage.

Transfusion 20101101

Calculations of binding affinity between C8-substituted GTP analogs and the bacterial cell-division protein FtsZ.

European biophysics journal : EBJ 20101101

Construction of a dengue virus type 4 reporter replicon and analysis of temperature-sensitive mutations in non-structural proteins 3 and 5.

The Journal of general virology 20101101

Use of the GTPγS ([35S]GTPγS and Eu-GTPγS) binding assay for analysis of ligand potency and efficacy at G protein-coupled receptors.

British journal of pharmacology 20101101

Comparison of the pharmacological properties of human and rat histamine H(3)-receptors.

Biochemical pharmacology 20101101

A silk platform that enables electrophysiology and targeted drug delivery in brain astroglial cells.

Biomaterials 20101101

Loxoribine, a selective Toll-like receptor 7 agonist, induces maturation of human monocyte-derived dendritic cells and stimulates their Th-1- and Th-17-polarizing capability.

International immunopharmacology 20101101

Renal function and vasomotor activity in mice lacking the Cyp4a14 gene.

Experimental biology and medicine (Maywood, N.J.) 20101101

A post-burst after depolarization is mediated by group i metabotropic glutamate receptor-dependent upregulation of Ca(v)2.3 R-type calcium channels in CA1 pyramidal neurons.

PLoS biology 20101101

Regulation of Na+/K+ ATPase transport velocity by RNA editing.

PLoS biology 20101101

G-octamer formation from N⁹ modified guanine derivatives.

Nucleosides, nucleotides & nucleic acids 20101101

Synthesis and substrate validation of cap analogs containing 7-deazaguanosine moiety by RNA polymerase.

Nucleosides, nucleotides & nucleic acids 20101101

Making of viral replication organelles by remodeling interior membranes.

Viruses 20101101

Modulatory Role of Nitric Oxide/cGMP System in Endothelin-1-Induced Signaling Responses in Vascular Smooth Muscle Cells.

Current cardiology reviews 20101101

Modulation of Gi Proteins in Hypertension: Role of Angiotensin II and Oxidative Stress.

Current cardiology reviews 20101101

Selenium compounds activate ATM-dependent DNA damage response via the mismatch repair protein hMLH1 in colorectal cancer cells.

The Journal of biological chemistry 20101022

Oligo-guanosine nucleotide induces neuropilin-1 internalization in endothelial cells and inhibits angiogenesis.

Blood 20101021

Refinement of DNA structures through near-edge X-ray absorption fine structure analysis: applications on guanine and cytosine nucleobases, nucleosides, and nucleotides.

The journal of physical chemistry. B 20101021

Inhibitory effect of the natural product betulin and its derivatives against the intracellular bacterium Chlamydia pneumoniae.

Biochemical pharmacology 20101015

One-pot etherification of purine nucleosides and pyrimidines.

Organic letters 20101015

Method for the rapid detection and molecular characterization of DNA alkylating agents by MALDI-TOF mass spectrometry.

Analytical chemistry 20101015

Discovery of N(2)-(1-carboxyethyl)guanosine 5'-monophosphate as an umami-enhancing maillard-modified nucleotide in yeast extracts.

Journal of agricultural and food chemistry 20101013

G protein-mediated Ca²+-sensitization of CPI-17 phosphorylation in arterial smooth muscle.

Biochemical and biophysical research communications 20101008

Extreme nucleoside concentrations in a marine annelid: a novel nucleoside storing cell in the polychaete Nereis virens.

Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology 20101001

Ribavirin as an anti-cancer therapy: acute myeloid leukemia and beyond?

Leukemia & lymphoma 20101001

Redox regulatory mechanism of transnitrosylation by thioredoxin.

Molecular & cellular proteomics : MCP 20101001

A homogeneous method to measure nucleotide exchange by α-subunits of heterotrimeric G-proteins using fluorescence polarization.

Assay and drug development technologies 20101001

Metabolomic profiling reveals biochemical pathways and biomarkers associated with pathogenesis in cystic fibrosis cells.

The Journal of biological chemistry 20101001

In situ evaluation of chromium-DNA damage using a DNA-electrochemical biosensor.

Analytical and bioanalytical chemistry 20101001

Modulation of N-type calcium currents by presynaptic imidazoline receptor activation in rat superior cervical ganglion neurons.

Experimental physiology 20101001

Transcription regulation of the Escherichia coli pcnB gene coding for poly(A) polymerase I: roles of ppGpp, DksA and sigma factors.

Molecular genetics and genomics : MGG 20101001

Investigation of riboflavin sensitized degradation of purine and pyrimidine derivatives of DNA and RNA under UVA and UVB.

Biochemical and biophysical research communications 20101001

A metazoan ortholog of SpoT hydrolyzes ppGpp and functions in starvation responses.

Nature structural & molecular biology 20101001

Colon tumor cell growth-inhibitory activity of sulindac sulfide and other nonsteroidal anti-inflammatory drugs is associated with phosphodiesterase 5 inhibition.

Cancer prevention research (Philadelphia, Pa.) 20101001

Efficient synthesis of the tRNA nucleoside preQ0, 7-cyano-7-deazaguanosine, via microwave-assisted iodo→carbonitrile exchange.

Chemistry & biodiversity 20101001

Identification of a quality-control mechanism for mRNA 5'-end capping.

Nature 20100930

Human kisspeptins activate neuropeptide FF2 receptor.

Neuroscience 20100929

Characterization of caged compounds binding to proteins by NMR spectroscopy.

Biochemical and biophysical research communications 20100924

The 5'-7-methylguanosine cap on eukaryotic mRNAs serves both to stimulate canonical translation initiation and to block an alternative pathway.

Molecular cell 20100924

Development and application of an HILIC-MS/MS method for the quantitation of nucleotides in infant formula.

Journal of agricultural and food chemistry 20100922

Comparisons between chemical mapping and binding to isoenergetic oligonucleotide microarrays reveal unexpected patterns of binding to the Bacillus subtilis RNase P RNA specificity domain.

Biochemistry 20100921

Structure of the RNA binding domain of a DEAD-box helicase bound to its ribosomal RNA target reveals a novel mode of recognition by an RNA recognition motif.

Journal of molecular biology 20100917

Electrocatalytic oxidation behavior of guanosine at graphene, chitosan and Fe3O4 nanoparticles modified glassy carbon electrode and its determination.

Talanta 20100915

Methylated DNA causes a physical block to replication forks independently of damage signalling, O(6)-methylguanine or DNA single-strand breaks and results in DNA damage.

Journal of molecular biology 20100910

Cortical M1 receptor concentration increases without a concomitant change in function in Alzheimer's disease.

Journal of chemical neuroanatomy 20100901

Biosynthesis of wyosine derivatives in tRNA: an ancient and highly diverse pathway in Archaea.

Molecular biology and evolution 20100901

Endothelin A receptors mediate relaxation of guinea pig internal anal sphincter through cGMP pathway.

Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society 20100901

Antiproliferative effects induced by guanine-based purines require hypoxanthine-guanine phosphoribosyltransferase activity.

Biological chemistry 20100901

Reversal of TNP-470-induced endothelial cell growth arrest by guanine and guanine nucleosides.

The Journal of pharmacology and experimental therapeutics 20100901

Pegylated interferons alpha2a and alpha2b in the treatment of chronic hepatitis C.

Nature reviews. Gastroenterology & hepatology 20100901

Adeno-associated viral vector-induced overexpression of neuropeptide Y Y2 receptors in the hippocampus suppresses seizures.

Brain : a journal of neurology 20100901

Coupling between clathrin-dependent endocytic budding and F-BAR-dependent tubulation in a cell-free system.

Nature cell biology 20100901

Azole drugs are imported by facilitated diffusion in Candida albicans and other pathogenic fungi.

PLoS pathogens 20100901

Cure and curse: E. coli heat-stable enterotoxin and its receptor guanylyl cyclase C.

Toxins 20100901

Actions of the prototypical 5-HT1A receptor agonist 8-OH-DPAT at human alpha2-adrenoceptors: (+)8-OH-DPAT, but not (-)8-OH-DPAT is an alpha2B subtype preferential agonist.

European journal of pharmacology 20100825

Acute withdrawal from chronic escalating-dose binge cocaine administration alters kappa opioid receptor stimulation of [35S] guanosine 5'-O-[gamma-thio]triphosphate acid binding in the rat ventral tegmental area.

Neuroscience 20100825

Endothelin-1 (ET-1) increases the expression of remodeling genes in vascular smooth muscle through linked calcium and cAMP pathways: role of a phospholipase A(2)(cPLA(2))/cyclooxygenase-2 (COX-2)/prostacyclin receptor-dependent autocrine loop.

The Journal of biological chemistry 20100820

Determination of nucleotides, nucleosides and their transformation products in Cordyceps by ion-pairing reversed-phase liquid chromatography-mass spectrometry.

Journal of chromatography. A 20100820

3'-5' tRNAHis guanylyltransferase in bacteria.

FEBS letters 20100820

Synthesis of nucleotidylated poliovirus VPg proteins.

The Journal of organic chemistry 20100820

G-protein-independent modulation of P-type calcium channels by mu-opioids in Purkinje neurons of rat.

Neuroscience letters 20100816

Comparison of the in vitro replication of the 7-(2-oxoheptyl)-1,N2-etheno-2'-deoxyguanosine and 1,N2-etheno-2'-deoxyguanosine lesions by Sulfolobus solfataricus P2 DNA polymerase IV (Dpo4).

Chemical research in toxicology 20100816

Design, synthesis and evaluation of a novel double pro-drug: INX-08189. A new clinical candidate for hepatitis C virus.

Bioorganic & medicinal chemistry letters 20100815

Ion-pair high-performance liquid chromatography with diode array detection coupled to dual electrospray atmospheric pressure chemical ionization time-of-flight mass spectrometry for the determination of nucleotides in baby foods.

Journal of chromatography. A 20100806

Agonist-dependent modulation of G-protein coupling and transduction of 5-HT1A receptors in rat dorsal raphe nucleus.

The international journal of neuropsychopharmacology 20100801

Δ⁹-Tetrahydrocannabivarin suppresses in vitro epileptiform and in vivo seizure activity in adult rats.

Epilepsia 20100801

Antioxidant defenses in the rat placenta in late gestation: increased labyrinthine expression of superoxide dismutases, glutathione peroxidase 3, and uncoupling protein 2.

Biology of reproduction 20100801

Ex vivo delta opioid receptor autoradiography: CNS receptor occupancy of two novel compounds over their antihyperalgesic dose range.

Pharmacology, biochemistry, and behavior 20100801

Gi protein coupling to adenosine A1-A2A receptor heteromers in human brain caudate nucleus.

Journal of neurochemistry 20100801

Creation of a genome-wide metabolic pathway database for Populus trichocarpa using a new approach for reconstruction and curation of metabolic pathways for plants.

Plant physiology 20100801

Guanosine 5'-diphosphate 3'-diphosphate (ppGpp) as a negative modulator of polynucleotide phosphorylase activity in a 'rare' actinomycete.

Molecular microbiology 20100801

Decreased expression of spine-associated Rap guanosine triphosphatase-activating protein (SPAR) in glutamate-treated primary hippocampal neurons.

Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia 20100801

Self-quenching smart probes as a platform for the detection of sequence-specific UV-induced DNA photodamage.

Analytical and bioanalytical chemistry 20100801

Resistance to endotoxic shock in mice lacking natriuretic peptide receptor-A.

British journal of pharmacology 20100801

Molecular cloning, chromosomal localization and expression pattern of porcine ADP-ribosylation factor(Arf) gene family.

Animal science journal = Nihon chikusan Gakkaiho 20100801

Involvement of kappa opioid receptors in the formalin-induced inhibition of analgesic tolerance to morphine via suppression of conventional protein kinase C activation.

The Journal of pharmacy and pharmacology 20100801

Long-term adaptation to high doses of morphine causes desensitization of mu-OR- and delta-OR-stimulated G-protein response in forebrain cortex but does not decrease the amount of G-protein alpha subunits.

Medical science monitor : international medical journal of experimental and clinical research 20100801

Trichomonas transmembrane cyclases result from massive gene duplication and concomitant development of pseudogenes.

PLoS neglected tropical diseases 20100801

A screening pipeline for antiparasitic agents targeting cryptosporidium inosine monophosphate dehydrogenase.

PLoS neglected tropical diseases 20100801

Nucleotides in canine colostrum and milk at different stages of lactation.

Archives of animal nutrition 20100801

Direct effect of carbon monoxide on relaxation induced by electrical field stimulation in rat corpus cavernosum.

Korean journal of urology 20100801

[Simultaneous determination of 7 nucleosides in Asterias rollestoni using reversed-phase high performance liquid chromatography].

Se pu = Chinese journal of chromatography 20100801

Combination chemotherapy for influenza.

Viruses 20100801

Possibilities for RNA interference in developing hepatitis C virus therapeutics.

Viruses 20100801

Bacterial heat-stable enterotoxins: translation of pathogenic peptides into novel targeted diagnostics and therapeutics.

Toxins 20100801

Assessment of the role of renal organic anion transporters in drug-induced nephrotoxicity.

Toxins 20100801

Crystal structure of human RNA helicase A (DHX9): structural basis for unselective nucleotide base binding in a DEAD-box variant protein.

Journal of molecular biology 20100723

Regulation of redox signaling involving chemical conjugation of protein thiols by nitric oxide and electrophiles.

Bioconjugate chemistry 20100721

Design of single-stranded nucleic acid binding peptides based on nucleocapsid CCHC-box zinc-binding domains.

Journal of the American Chemical Society 20100721

Structural basis for conformational dynamics of GTP-bound Ras protein.

The Journal of biological chemistry 20100716

(15)N Double-labeled guanosine from inosine through ring-opening-ring-closing and one-pot Pd-catalyzed C-O and C-N cross-coupling reactions.

The Journal of organic chemistry 20100716

cGMP is required for seed germination in Arabidopsis thaliana.

Journal of plant physiology 20100715

A real-time fluorescent assay of the purified nitric oxide receptor, guanylyl cyclase.

Analytical biochemistry 20100715

RNA internal loops with tandem AG pairs: the structure of the 5'GAGU/3'UGAG loop can be dramatically different from others, including 5'AAGU/3'UGAA.

Biochemistry 20100713

Phosphoramidate ProTides of 2'-C-methylguanosine as highly potent inhibitors of hepatitis C virus. Study of their in vitro and in vivo properties.

Journal of medicinal chemistry 20100708

Cytidylyl and uridylyl cyclase activity of bacillus anthracis edema factor and Bordetella pertussis CyaA.

Biochemistry 20100706

Activated RhoA binds to the pleckstrin homology (PH) domain of PDZ-RhoGEF, a potential site for autoregulation.

The Journal of biological chemistry 20100702

Human BLCAP transcript: new editing events in normal and cancerous tissues.

International journal of cancer 20100701

Selective alterations of the CB1 receptors and the fatty acid amide hydrolase in the ventral striatum of alcoholics and suicides.

Journal of psychiatric research 20100701

Efficient expression of human soluble guanylate cyclase in Escherichia coli and its signaling-related interaction with nitric oxide.

Amino acids 20100701

Nociceptin inhibits uterine contractions in term-pregnant rats by signaling through multiple pathways.

Biology of reproduction 20100701

Interaction of oligonucleotide-based amphiphilic block copolymers with cell membrane models.

Journal of colloid and interface science 20100701

FAAH-/- mice display differential tolerance, dependence, and cannabinoid receptor adaptation after delta 9-tetrahydrocannabinol and anandamide administration.

Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20100701

Stress impairs GABAergic network function in the hippocampus by activating nongenomic glucocorticoid receptors and affecting the integrity of the parvalbumin-expressing neuronal network.

Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20100701

Nitric oxide and downstream second messenger cGMP and cAMP enhance adipogenesis in primary human preadipocytes.

Cytotherapy 20100701

Atrial natriuretic peptide and oxidative stress.

Peptides 20100701

Oxidation of the diphosphoinositol polyphosphate phosphohydrolase-like Nudix hydrolase Aps from Drosophila melanogaster induces thermolability--A possible regulatory switch?

The international journal of biochemistry & cell biology 20100701

A novel nucleoside analog, 1-beta-d-ribofuranosyl-3-ethynyl-[1,2,4]triazole (ETAR), exhibits efficacy against a broad range of flaviviruses in vitro.

Antiviral research 20100701

Famciclovir: a focus on efficacy and safety.

Expert opinion on drug safety 20100701

The acidic A-domain of Arabidopsis TOC159 occurs as a hyperphosphorylated protein.

Plant physiology 20100701

The sigma(E) stress response is required for stress-induced mutation and amplification in Escherichia coli.

Molecular microbiology 20100701

Pharmacological characterization of a novel cannabinoid ligand, MDA19, for treatment of neuropathic pain.

Anesthesia and analgesia 20100701

Structural requirements for Caenorhabditis elegans DcpS substrates based on fluorescence and HPLC enzyme kinetic studies.

The FEBS journal 20100701

Oxidative stress markers in the brain of patients with cirrhosis and hepatic encephalopathy.

Hepatology (Baltimore, Md.) 20100701

A metazoan/plant-like capping enzyme and cap modified nucleotides in the unicellular eukaryote Trichomonas vaginalis.

PLoS pathogens 20100701

Resistance to integrase inhibitors.

Viruses 20100701

New trends in nucleoside biotechnology.

Acta naturae 20100701

Analysis of seven purines and pyrimidines in pork meat products by ultra high performance liquid chromatography-tandem mass spectrometry.

Journal of chromatography. A 20100625

Direct measurement of the rates and barriers on forward and reverse diffusions of intramolecular collision in overhang oligonucleotides.

The journal of physical chemistry. B 20100624

Rab14 from Bombyx mori (Lepidoptera: Bombycidae) shows ATPase activity.

Biology letters 20100623

Chronic constriction injury reduces cannabinoid receptor 1 activity in the rostral anterior cingulate cortex of mice.

Brain research 20100621

A non-empirical chromophoric interpretation of CD spectra of DNA G-quadruplex structures.

Organic & biomolecular chemistry 20100621

Structure and gelation mechanism of tunable guanosine-based supramolecular hydrogels.

Langmuir : the ACS journal of surfaces and colloids 20100615

The oxidation of 8-oxo-7,8-dihydroguanine by iodine.

Bioorganic & medicinal chemistry letters 20100615

ppGpp analogues inhibit synthetase activity of Rel proteins from Gram-negative and Gram-positive bacteria.

Bioorganic & medicinal chemistry 20100615

Cost of unneeded proteins in E. coli is reduced after several generations in exponential growth.

Molecular cell 20100611

Extracellular cAMP inhibits P2X receptors in rat sensory neurones through G protein-mediated mechanism.

Acta physiologica (Oxford, England) 20100601

Mechanism for the regulation of mammalian cGMP phosphodiesterase6. 2: isolation and characterization of the transducin-activated form.

Molecular and cellular biochemistry 20100601

HL-1 cells express an inwardly rectifying K+ current activated via muscarinic receptors comparable to that in mouse atrial myocytes.

Pflugers Archiv : European journal of physiology 20100601

Hydrogen-bond-directed giant vesicles of guanosine derivatives in water: formation, structure, and stability.

Langmuir : the ACS journal of surfaces and colloids 20100601

Novel anticytomegalovirus activity of immunosuppressant mizoribine and its synergism with ganciclovir.

The Journal of pharmacology and experimental therapeutics 20100601

Meiotic cell cycle arrest in mammalian oocytes.

Journal of cellular physiology 20100601

A fluorescence anisotropy assay for the muscarinic M1 G-protein-coupled receptor.

Assay and drug development technologies 20100601

NADPH-diaphorase activity and NO synthase expression in the olfactory epithelium of the bovine.

Anatomia, histologia, embryologia 20100601

SNARE-dependent glutamate release in megakaryocytes.

Experimental hematology 20100601

Kappa opioid mediation of cannabinoid effects of the potent hallucinogen, salvinorin A, in rodents.

Psychopharmacology 20100601

Specific oxidative stress profile associated with partial striatal dopaminergic depletion by 6-hydroxydopamine as assessed by a novel multifunctional marker molecule.

Free radical research 20100601

Absence of mitochondrial toxicity in hearts of transgenic mice treated with abacavir.

Cardiovascular toxicology 20100601

Inhibition of G-protein-activated inwardly rectifying K+ channels by the selective norepinephrine reuptake inhibitors atomoxetine and reboxetine.

Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20100601

Electrochemical simulation of oxidation processes involving nucleic acids monitored with electrospray ionization-mass spectrometry.

Analytical and bioanalytical chemistry 20100601

Simultaneous determination of nine nucleosides and nucleobases in different Fritillaria species by HPLC-diode array detector.

Journal of separation science 20100601

Homologous desensitization of guanylyl cyclase A, the receptor for atrial natriuretic peptide, is associated with a complex phosphorylation pattern.

The FEBS journal 20100601

A point mutation in the polymerase of Potato virus Y confers virulence toward the Pvr4 resistance of pepper and a high competitiveness cost in susceptible cultivar.

Molecular plant-microbe interactions : MPMI 20100601

Synthesis of new derivatives of 8-oxoG-clamp for better understanding the recognition mode and improvement of selective affinity.

Bioorganic & medicinal chemistry 20100601

Nucleotides and nucleosides in ovine and caprine milk during lactation.

Journal of dairy science 20100601

A role for borg5 during trophectoderm differentiation.

Stem cells (Dayton, Ohio) 20100601

Evaluation of activation of G proteins in response to thyroid stimulating hormone in thyroid gland cells from euthyroid and hyperthyroid cats.

American journal of veterinary research 20100601

Preparation of DNA and RNA fragments containing guanine N(2)-thioalkyl tethers.

Current protocols in nucleic acid chemistry 20100601

Two novel point mutations in clinical Staphylococcus aureus reduce linezolid susceptibility and switch on the stringent response to promote persistent infection.

PLoS pathogens 20100601

The plant cannabinoid Delta9-tetrahydrocannabivarin can decrease signs of inflammation and inflammatory pain in mice.

British journal of pharmacology 20100601

A role for L-alpha-lysophosphatidylinositol and GPR55 in the modulation of migration, orientation and polarization of human breast cancer cells.

British journal of pharmacology 20100601

Characterization of the structures of phosphodiesterase 10 binding with adenosine 3',5'-monophosphate and guanosine 3',5'-monophosphate by hybrid quantum mechanical/molecular mechanical calculations.

The journal of physical chemistry. B 20100527

Oxidative modification of guanine bases initiated by oxyl radicals derived from photolysis of azo compounds.

The journal of physical chemistry. B 20100520

Discovery of GS-9131: Design, synthesis and optimization of amidate prodrugs of the novel nucleoside phosphonate HIV reverse transcriptase (RT) inhibitor GS-9148.

Bioorganic & medicinal chemistry 20100515

Complementary interactions of the rod PDE6 inhibitory subunit with the catalytic subunits and transducin.

The Journal of biological chemistry 20100514

Collision-induced dissociation (CID) of guanine radical cation in the gas phase: an experimental and computational study.

Physical chemistry chemical physics : PCCP 20100514

Triggering of guanosine self-assembly by light.

Angewandte Chemie (International ed. in English) 20100510

Differential fluorescence quenching of fluorescent nucleic acid base analogues by native nucleic acid monophosphates.

The journal of physical chemistry. B 20100506

A functional human Poly(A) site requires only a potent DSE and an A-rich upstream sequence.

The EMBO journal 20100505

Induction of type I interferon by RNA viruses: cellular receptors and their substrates.

Amino acids 20100501

Rapid cleavage of RNA by RNase E in the absence of 5' monophosphate stimulation.

Molecular microbiology 20100501

Quantitative determination of urinary 8-oxo-7,8-dihydro-2'-deoxyguanosine, 8-oxo-7,8-dihydroguanine, 8-oxo-7,8-dihydroguanosine, and their non-oxidized forms: daily concentration profile in healthy volunteers.

Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals 20100501

The multiple actions of NO.

Pflugers Archiv : European journal of physiology 20100501

Effects of motilin on intracellular free calcium in cultured smooth muscle cells from the antrum of neonatal rats.

Acta physiologica (Oxford, England) 20100501

Impact of the DRY motif and the missing 'ionic lock' on constitutive activity and G-protein coupling of the human histamine H4 receptor.

The Journal of pharmacology and experimental therapeutics 20100501

Regulation of the autophagic machinery in human neutrophils.

European journal of immunology 20100501

Anti-inflammatory properties of CB1-receptor antagonist involves beta2 adrenoceptors.

The Journal of pharmacology and experimental therapeutics 20100501

Mycophenolic acid differentially affects dendritic cell maturation induced by tumor necrosis factor-alpha and lipopolysaccharide through a different modulation of MAPK signaling.

Molecular immunology 20100501

Synapse pathology in psychiatric and neurologic disease.

Current neurology and neuroscience reports 20100501

Characterization of oxidative guanine damage and repair in mammalian telomeres.

PLoS genetics 20100501

A survey of genomic traces reveals a common sequencing error, RNA editing, and DNA editing.

PLoS genetics 20100501

Changes in purines concentration in the cerebrospinal fluid of patients experiencing pain: a case-control study.

Neuroscience letters 20100426

Gi-protein inhibitor, guanosine 5'-O-(2-thiodiphosphate), induces senescence-associated beta-galactosidase positive cell formation through CREB phosphorylation.

Life sciences 20100424

Discovery and characterization of an amidinotransferase involved in the modification of archaeal tRNA.

The Journal of biological chemistry 20100423

Intramolecular movements in EF-G, trapped at different stages in its GTP hydrolytic cycle, probed by FRET.

Journal of molecular biology 20100416

Colorimetric biosensing of mercury(II) ion using unmodified gold nanoparticle probes and thrombin-binding aptamer.

Biosensors & bioelectronics 20100415

Postsynaptic density-93 deficiency protects cultured cortical neurons from N-methyl-D-aspartate receptor-triggered neurotoxicity.

Neuroscience 20100414

Polymeric structures and dynamic properties of the bacterial actin AlfA.

Journal of molecular biology 20100409

Visualizing the molecular interactions of a nucleotide analog, GS-9148, with HIV-1 reverse transcriptase-DNA complex.

Journal of molecular biology 20100409

Persistent, well-defined, monodisperse, pi-conjugated organic nanoparticles via G-quadruplex self-assembly.

Journal of the American Chemical Society 20100407

Gender- and age-dependent changes in nucleoside levels in the cerebral cortex and white matter of the human brain.

Brain research bulletin 20100405

Selective D1 agonism but not D2 antagonism is reflected in cAMP and cGMP levels in rat CSF.

Brain research bulletin 20100405

Inhibition of fatty-acid amide hydrolase and CB1 receptor antagonism differentially affect behavioural responses in normal and PCP-treated rats.

The international journal of neuropsychopharmacology 20100401

Regulation of cortical and hippocampal 5-HT(1A) receptor function by corticosterone in GR+/- mice.

Psychoneuroendocrinology 20100401

Antiviral efficacy of EICAR against canine distemper virus (CDV) in vitro.

Research in veterinary science 20100401

Combined radionuclide-chemotherapy and in vivo imaging of hepatocellular carcinoma cells after transfection of a triple-gene construct, NIS, HSV1-sr39tk, and EGFP.

Cancer letters 20100401

Identification of a novel 'almost neutral' micro-opioid receptor antagonist in CHO cells expressing the cloned human mu-opioid receptor.

Synapse (New York, N.Y.) 20100401

In vitro and in vivo pharmacological characterization of two novel selective cannabinoid CB(2) receptor inverse agonists.

Pharmacological research 20100401

Increased CYP2J3 expression reduces insulin resistance in fructose-treated rats and db/db mice.

Diabetes 20100401

Sigma 1 receptor modulation of G-protein-coupled receptor signaling: potentiation of opioid transduction independent from receptor binding.

Molecular pharmacology 20100401

Adenosine inhibits paraventricular pre-sympathetic neurons through ATP-dependent potassium channels.

Journal of neurochemistry 20100401

Subcellular localization of mu-opioid receptor G(s) signaling.

The Journal of pharmacology and experimental therapeutics 20100401

Genome-wide screening of genes whose enhanced expression affects glycogen accumulation in Escherichia coli.

DNA research : an international journal for rapid publication of reports on genes and genomes 20100401

eNOS plays a major role in adiponectin synthesis in adipocytes.

American journal of physiology. Endocrinology and metabolism 20100401

Vital role of protein kinase C-related kinase in the formation and stability of neurites during hypoxia.

Journal of neurochemistry 20100401

Paradoxical relationship between RAVE (relative activity versus endocytosis) values of several opioid receptor agonists and their liability to cause dependence.

Acta pharmacologica Sinica 20100401

Triggering of TLR7 and TLR8 expressed by human lung cancer cells induces cell survival and chemoresistance.

The Journal of clinical investigation 20100401

LyGDI is a promising biomarker for ovarian cancer.

International journal of gynecological cancer : official journal of the International Gynecological Cancer Society 20100401

Structural basis for Fe-S cluster assembly and tRNA thiolation mediated by IscS protein-protein interactions.

PLoS biology 20100401

[Human lung cancer: role of TLR7 and TLR8 in cell survival and chemoresistance].

Medecine sciences : M/S 20100401

In vitro reconstitution of SARS-coronavirus mRNA cap methylation.

PLoS pathogens 20100401

[Studies on photoinduced electron and proton transfer reactions of nucleic acid and aromatic ketone].

Guang pu xue yu guang pu fen xi = Guang pu 20100401

Toxins-useful biochemical tools for leukocyte research.

Toxins 20100401

A rearrangement of the guanosine-binding site establishes an extended network of functional interactions in the Tetrahymena group I ribozyme active site.

Biochemistry 20100330

Opioid-induced long-term potentiation in the spinal cord is a presynaptic event.

The Journal of neuroscience : the official journal of the Society for Neuroscience 20100324

Flexible recognition of the tRNA G18 methylation target site by TrmH methyltransferase through first binding and induced fit processes.

The Journal of biological chemistry 20100319

The proline-rich N-terminal domain of G18 exhibits a novel G protein regulatory function.

The Journal of biological chemistry 20100319

NSF independent fusion of Salmonella-containing late phagosomes with early endosomes.

FEBS letters 20100319

Comparative biochemical and pharmacological characterization of a novel, NOP receptor selective hexapeptide, Ac-RYYRIR-ol.

Brain research bulletin 20100316

8-Hydroxydeoxyguanosine: a new potential independent prognostic factor in breast cancer.

British journal of cancer 20100316

DNA polymerases as potential therapeutic targets for cancers deficient in the DNA mismatch repair proteins MSH2 or MLH1.

Cancer cell 20100316

Exon array analyses across the NCI-60 reveal potential regulation of TOP1 by transcription pausing at guanosine quartets in the first intron.

Cancer research 20100315

G proteins in reverse mode: receptor-mediated GTP release inhibits G protein and effector function.

The Journal of biological chemistry 20100312

Discovery of 4-(4-(2-((5-Hydroxy-1,2,3,4-tetrahydronaphthalen-2-yl)(propyl)amino)ethyl)piperazin-1-yl)quinolin-8-ol and its analogues as highly potent dopamine D2/D3 agonists and as iron chelator: in vivo activity indicates potential application in symptomatic and neuroprotective therapy for Parkinson's disease.

Journal of medicinal chemistry 20100311

Mutagenic potential of DNA glycation: miscoding by (R)- and (S)-N2-(1-carboxyethyl)-2'-deoxyguanosine.

Biochemistry 20100309

Identification of orthosteric and allosteric site mutations in M2 muscarinic acetylcholine receptors that contribute to ligand-selective signaling bias.

The Journal of biological chemistry 20100305

Preparation of the 2'-deoxynucleosides of 2,6-diaminopurine and isoguanine by direct glycosylation.

The Journal of organic chemistry 20100305

Mutation versus repair: NEIL1 removal of hydantoin lesions in single-stranded, bulge, bubble, and duplex DNA contexts.

Biochemistry 20100302

Effect of ribavirin on the frequency of RNase L cleavage sites within the hepatitis C viral genome.

Journal of viral hepatitis 20100301

Nucleoside map of the human central nervous system.

Neurochemical research 20100301

Molecular mechanisms of action and in vivo validation of an M4 muscarinic acetylcholine receptor allosteric modulator with potential antipsychotic properties.

Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20100301

Chuanxiongzine relaxes isolated corpus cavernosum strips and raises intracavernous pressure in rabbits.

International journal of impotence research 20100301

Mechanisms of copy number variation and hybrid gene formation in the KIR immune gene complex.

Human molecular genetics 20100301

Phosphorylation of the mu-opioid receptor at tyrosine 166 (Tyr3.51) in the DRY motif reduces agonist efficacy.

Molecular pharmacology 20100301

Long-term fluoxetine treatment modulates cannabinoid type 1 receptor-mediated inhibition of adenylyl cyclase in the rat prefrontal cortex through 5-hydroxytryptamine 1A receptor-dependent mechanisms.

Molecular pharmacology 20100301

Hyperglycemia impairs proteasome function by methylglyoxal.

Diabetes 20100301

Lead identification and optimization of diaminopyrimidines as histamine H4 receptor ligands.

Inflammation research : official journal of the European Histamine Research Society ... [et al.] 20100301

UR-60427, a novel H4 receptor-inverse agonist that shows good efficacy in a rat asthma model.

Inflammation research : official journal of the European Histamine Research Society ... [et al.] 20100301

Central and peripheral consequences of the chronic blockade of CB1 cannabinoid receptor with rimonabant or taranabant.

Journal of neurochemistry 20100301

Intraneuronal amyloid beta accumulation and oxidative damage to nucleic acids in Alzheimer disease.

Neurobiology of disease 20100301

Cloning, purification and characterisation of a recombinant purine nucleoside phosphorylase from Bacillus halodurans Alk36.

Extremophiles : life under extreme conditions 20100301

Hepatitis C virus induces oxidative stress, DNA damage and modulates the DNA repair enzyme NEIL1.

Journal of gastroenterology and hepatology 20100301

Homogeneous GTP binding assay employing QRET technology.

Journal of biomolecular screening 20100301

Gibberellic acid and cGMP-dependent transcriptional regulation in Arabidopsis thaliana.

Plant signaling & behavior 20100301

Mechanisms involved in the antinociception induced by systemic administration of guanosine in mice.

British journal of pharmacology 20100301

Binding of GTPgamma[35S] is regulated by GDP and receptor activation. Studies with the nociceptin/orphanin FQ receptor.

British journal of pharmacology 20100301

Multiple receptor tyrosine kinases are expressed in adult rat retinal ganglion cells as revealed by single-cell degenerate primer polymerase chain reaction.

Upsala journal of medical sciences 20100301

Synthesis and properties of diazirinyl organo-platinum compounds for manipulations of photoaffinity labeled components.

Chemical & pharmaceutical bulletin 20100301

G-less cassette in vitro transcription using HeLa cell nuclear extracts.

Cold Spring Harbor protocols 20100301

Role of RecA and the SOS response in thymineless death in Escherichia coli.

PLoS genetics 20100301

Urinary 8-hydroxydeoxyguanosine levels and psychological reactions after sleep deprivation.

Journal of UOEH 20100301

YfiBNR mediates cyclic di-GMP dependent small colony variant formation and persistence in Pseudomonas aeruginosa.

PLoS pathogens 20100301

Cholera toxin: an intracellular journey into the cytosol by way of the endoplasmic reticulum.

Toxins 20100301

Role of transmembrane domain 4 in ligand permeation by Crithidia fasciculata equilibrative nucleoside transporter 2 (CfNT2).

The Journal of biological chemistry 20100226

Solvent-induced switching between two supramolecular assemblies of a guanosine-terthiophene conjugate.

Organic & biomolecular chemistry 20100221

Europium-labeled GTP as a general nonradioactive substitute for [(35)S]GTPgammaS in high-throughput G protein studies.

Analytical biochemistry 20100215

Influence of substrate complexity on the diastereoselective formation of spiroiminodihydantoin and guanidinohydantoin from chromate oxidation.

Chemical research in toxicology 20100215

Protein-precursor tRNA contact leads to sequence-specific recognition of 5' leaders by bacterial ribonuclease P.

Journal of molecular biology 20100212

Development of (S)-N6-(2-(4-(isoquinolin-1-yl)piperazin-1-yl)ethyl)-N6-propyl-4,5,6,7-tetrahydrobenzo[d]-thiazole-2,6-diamine and its analogue as a D3 receptor preferring agonist: potent in vivo activity in Parkinson's disease animal models.

Journal of medicinal chemistry 20100211

Synthesis of dihydrofuroaporphine derivatives: identification of a potent and selective serotonin 5-HT 1A receptor agonist.

Journal of medicinal chemistry 20100211

Synthesis and opioid activity of enantiomeric N-substituted 2,3,4,4a,5,6,7,7a-octahydro-1H-benzofuro[3,2-e]isoquinolines.

Journal of medicinal chemistry 20100211

Supramolecular ABC triblock copolymers via one-pot, orthogonal self-assembly.

Journal of the American Chemical Society 20100210

Synthesis and crystal structure of 2'-se-modified guanosine containing DNA.

The Journal of organic chemistry 20100205

A stable G-quartet binds to a huntingtin protein fragment containing expanded polyglutamine tracks.

Journal of neuroscience research 20100201

Guanosine prevents thermal hyperalgesia in a rat model of peripheral mononeuropathy.

The journal of pain : official journal of the American Pain Society 20100201

The synthesis and function of the alarmone (p)ppGpp in firmicutes.

International journal of medical microbiology : IJMM 20100201

Detection of DNA damage in fish Oreochromis mossambicus induced by co-exposure to phenanthrene and nitrite by ESI-MS/MS.

Environmental science and pollution research international 20100201

The roles of the dystrophin-associated glycoprotein complex at the synapse.

Molecular neurobiology 20100201

A bulky platinum triamine complex that reacts faster with guanosine 5'-monophosphate than with N-acetylmethionine.

Journal of inorganic biochemistry 20100201

Cannabidiol displays antiepileptiform and antiseizure properties in vitro and in vivo.

The Journal of pharmacology and experimental therapeutics 20100201

Amoxapine inhibits the delayed rectifier outward K+ current in mouse cortical neurons via cAMP/protein kinase A pathways.

The Journal of pharmacology and experimental therapeutics 20100201

Effects of some modulators on purine nucleoside phosphorylase activity in myocardial tissue.

Scandinavian journal of clinical and laboratory investigation 20100201

Electrophysiological effects of guanosine and MK-801 in a quinolinic acid-induced seizure model.

Experimental neurology 20100201

Differential modulation of mu-opioid receptor signaling to adenylyl cyclase by regulators of G protein signaling proteins 4 or 8 and 7 in permeabilised C6 cells is Galpha subtype dependent.

Journal of neurochemistry 20100201

Elongation factors are involved in cytokinesis of sea urchin eggs.

Genes to cells : devoted to molecular & cellular mechanisms 20100201

Origin of highly pathogenic porcine reproductive and respiratory syndrome virus, China.

Emerging infectious diseases 20100201

A new nuclear function of the Entamoeba histolytica glycolytic enzyme enolase: the metabolic regulation of cytosine-5 methyltransferase 2 (Dnmt2) activity.

PLoS pathogens 20100201

Neoadjuvant immunotherapy enhances radiosensitivity through natural killer cell activation.

Cancer biotherapy & radiopharmaceuticals 20100201

Mouse strain differences in locomotor, sensitisation and rewarding effect of heroin; association with alterations in MOP-r activation and dopamine transporter binding.

The European journal of neuroscience 20100201

[Molecular cloning, gene expression and characterization of purine nucleoside phosphorylase from Pseudoalteromonas sp. XM2107].

Wei sheng wu xue bao = Acta microbiologica Sinica 20100201

[Study on influence of arbuscular mycorrhizal fungi Pinellia ternata yield and chemical composition].

Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20100201

Effect of propofol on cardiac function and gene expression after ischemic-reperfusion in isolated rat heart.

Korean journal of anesthesiology 20100201

Expression and contribution of satellite glial cells purinoceptors to pain transmission in sensory ganglia: an update.

Neuron glia biology 20100201

Ribonucleoside labeling with Os(VI): a methodological approach to evaluation of RNA methylation by HPLC-ICP-MS.

Metallomics : integrated biometal science 20100201

Pathological basis of symptoms and crises in sickle cell disorder: implications for counseling and psychotherapy.

Hematology reports 20100126

Comprehensive analysis of DNA strand breaks at the guanosine site induced by low-energy electron attachment.

Chemphyschem : a European journal of chemical physics and physical chemistry 20100118

Sensing purine nucleoside phosphorylase activity by using silver nanoparticles.

Biosensors & bioelectronics 20100115

Crystal structure of the ATPPase subunit and its substrate-dependent association with the GATase subunit: a novel regulatory mechanism for a two-subunit-type GMP synthetase from Pyrococcus horikoshii OT3.

Journal of molecular biology 20100115

Regulation of mRNA cap methylation.

The Biochemical journal 20100115

Solution structure of a unique G-quadruplex scaffold adopted by a guanosine-rich human intronic sequence.

Structure (London, England : 1993) 20100113

Study of phase transformation of guanosine 5'-monophosphate in drowning-out crystallization.

Applied biochemistry and biotechnology 20100101

Isotope labeling strategies for NMR studies of RNA.

Journal of biomolecular NMR 20100101

Direct agonist activity of tricyclic antidepressants at distinct opioid receptor subtypes.

The Journal of pharmacology and experimental therapeutics 20100101

Activity-mediated plasticity of GABA equilibrium potential in rat hippocampal CA1 neurons.

Experimental neurology 20100101

Monocyclic aromatic amines as potential human carcinogens: old is new again.

Carcinogenesis 20100101

Endogenous glucagon-like peptide-1 slows gastric emptying in healthy subjects, attenuating postprandial glycemia.

The Journal of clinical endocrinology and metabolism 20100101

Cap analog substrates reveal three clades of cap guanine-N2 methyltransferases with distinct methyl acceptor specificities.

RNA (New York, N.Y.) 20100101

Photophysics and photochemical studies of the vitamin B6 group and related derivatives.

Photochemistry and photobiology 20100101

Pumilio 2 controls translation by competing with eIF4E for 7-methyl guanosine cap recognition.

RNA (New York, N.Y.) 20100101

Facile and efficient approach for the synthesis of N(2)-dimethylaminomethylene-2'-O-methylguanosine.

Bioorganic & medicinal chemistry letters 20100101

Genetically engineered Salmonella typhimurium as an imageable therapeutic probe for cancer.

Cancer research 20100101

Intrinsic cellular defenses against virus infection by antiviral type I interferon.

Yonsei medical journal 20100101

A computational screen for site selective A-to-I editing detects novel sites in neuron specific Hu proteins.

BMC bioinformatics 20100101

Adenosine binding to low-molecular-weight purine nucleoside phosphorylase: the structural basis for recognition based on its complex with the enzyme from Schistosoma mansoni.

Acta crystallographica. Section D, Biological crystallography 20100101

Genetic analysis of the Staphylococcus epidermidis macromolecular synthesis operon: Serp1129 is an ATP binding protein and sigA transcription is regulated by both sigma(A)- and sigma(B)-dependent promoters.

BMC microbiology 20100101

Differentiation of intestinal epithelial cells mediated by cell confluence and/or exogenous nucleoside supplementation.

Cells, tissues, organs 20100101

Innovative agents for actinic keratosis and nanocarriers enhancing skin penetration.

Skin pharmacology and physiology 20100101

Expression profiles during dedifferentiation in newt lens regeneration revealed by expressed sequence tags.

Molecular vision 20100101

A new paradigm for antimicrobial host defense mediated by a nitrated cyclic nucleotide.

Journal of clinical biochemistry and nutrition 20100101

Targeting viral infection by microRNA inhibition.

Genome biology 20100101

The mitochondrial genome of the entomoparasitic green alga helicosporidium.

PloS one 20100101

Alternative splicing and extensive RNA editing of human TPH2 transcripts.

PloS one 20100101

The Mrs1 splicing factor binds the bI3 group I intron at each of two tetraloop-receptor motifs.

PloS one 20100101

The Arabidopsis wall associated kinase-like 10 gene encodes a functional guanylyl cyclase and is co-expressed with pathogen defense related genes.

PloS one 20100101

Alpha-1,2-mannosidase and hence N-glycosylation are required for regulatory T cell migration and allograft tolerance in mice.

PloS one 20100101

Molecular modulation of intestinal epithelial barrier: contribution of microbiota.

Journal of biomedicine & biotechnology 20100101

Expression and functional activity of nucleoside transporters in human choroid plexus.

Cerebrospinal fluid research 20100101

Temporal ChIP-on-Chip of RNA-Polymerase-II to detect novel gene activation events during photoreceptor maturation.

Molecular vision 20100101

Cloning, purification, and partial characterization of Bacillus subtilis urate oxidase expressed in Escherichia coli.

Journal of biomedicine & biotechnology 20100101

Alterations in adenosine metabolism and signaling in patients with chronic obstructive pulmonary disease and idiopathic pulmonary fibrosis.

PloS one 20100101

Shorter GT repeat polymorphism in the heme oxygenase-1 gene promoter has protective effect on ischemic stroke in dyslipidemia patients.

Journal of biomedical science 20100101

Signal transduction, receptors, mediators and genes: younger than ever - the 13th meeting of the Signal Transduction Society focused on aging and immunology.

Cell communication and signaling : CCS 20100101

Molecular characterisation of virulence graded field isolates of myxoma virus.

Virology journal 20100101

Quality evaluation of mycelial Antrodia camphorata using high-performance liquid chromatography (HPLC) coupled with diode array detector and mass spectrometry (DAD-MS).

Chinese medicine 20100101

Homeostatic imbalance of purine catabolism in first-episode neuroleptic-naïve patients with schizophrenia.

PloS one 20100101

The PPARbeta/delta agonist GW0742 relaxes pulmonary vessels and limits right heart hypertrophy in rats with hypoxia-induced pulmonary hypertension.

PloS one 20100101

Modulation by neuropeptide FF of the interaction of mu-opioid (MOP) receptor with G-proteins.

Neurochemistry international 20100101

Depletion of the non-coding regulatory 6S RNA in E. coli causes a surprising reduction in the expression of the translation machinery.

BMC genomics 20100101

Investigating a new generation of ribozymes in order to target HCV.

PloS one 20100101

Modern role for clopidogrel in management of atrial fibrillation and stroke reduction.

Vascular health and risk management 20100101

Production of recombinant proteins in E. coli by the heat inducible expression system based on the phage lambda pL and/or pR promoters.

Microbial cell factories 20100101

A plant natriuretic peptide-like molecule of the pathogen Xanthomonas axonopodis pv. citri causes rapid changes in the proteome of its citrus host.

BMC plant biology 20100101

Opposite changes in cannabinoid CB1 and CB2 receptor expression in human gliomas.

Neurochemistry international 20100101

Expression and aberrant promoter methylation of Wnt inhibitory factor-1 in human astrocytomas.

Journal of experimental & clinical cancer research : CR 20100101

Novel approaches to treat experimental pulmonary arterial hypertension: a review.

Journal of biomedicine & biotechnology 20100101

[Simultaneous determination of five nucleotides in Bulbus Fritillariae by RP-HPLC].

Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20100101

CXCR4 mediated chemotaxis is regulated by 5T4 oncofetal glycoprotein in mouse embryonic cells.

PloS one 20100101

Guanosine-induced decrease in side population of lung cancer cells: lack of correlation with ABCG2 expression.

Journal of biological regulators and homeostatic agents 20100101

Natural occurrence of 2',5'-linked heteronucleotides in marine sponges.

Marine drugs 20100101

Pattern recognition via the toll-like receptor system in the human female genital tract.

Mediators of inflammation 20100101

A comprehensive molecular interaction map for rheumatoid arthritis.

PloS one 20100101

Up-regulation of avian uncoupling protein in cold-acclimated and hyperthyroid ducklings prevents reactive oxygen species production by skeletal muscle mitochondria.

BMC physiology 20100101

Thrombospondin-1 null mice are resistant to hypoxia-induced pulmonary hypertension.

Journal of cardiothoracic surgery 20100101

The diagnostic value of endothelial function as a potential sensor of fatigue in health.

Vascular health and risk management 20100101

Advances in the treatment of Raynaud's phenomenon.

Vascular health and risk management 20100101

Is Lamarckian evolution relevant to medicine?

BMC medical genetics 20100101

Alterations in early cytokine-mediated immune responses to Plasmodium falciparum infection in Tanzanian children with mineral element deficiencies: a cross-sectional survey.

Malaria journal 20100101

Polyfunctional CD4+ T cell responses to a set of pathogenic arenaviruses provide broad population coverage.

Immunome research 20100101

[The clinical diagnostic value of a study of the activity of enzymes of the guanyl branch of purine metabolism in patients with ankylosing spondyloarthritis].

Terapevticheskii arkhiv 20100101

Effective inhibition of HCMV UL49 gene expression and viral replication by oligonucleotide external guide sequences and RNase P.

Virology journal 20100101

A human functional protein interaction network and its application to cancer data analysis.

Genome biology 20100101

Beneficial effects of a Q-ter based nutritional mixture on functional performance, mitochondrial function, and oxidative stress in rats.

PloS one 20100101

Adenosine thiamine triphosphate accumulates in Escherichia coli cells in response to specific conditions of metabolic stress.

BMC microbiology 20100101

Signal transduction mechanisms involved in S100A4-induced activation of the transcription factor NF-kappaB.

BMC cancer 20100101

Role of heme oxygenase in inflammation, insulin-signalling, diabetes and obesity.

Mediators of inflammation 20100101

From biological gastroenterology to fundamental neurosciences: how studies in gastric emptying have led to the discovery of a new mechanism of neuronal functioning.

Gastroenterologie clinique et biologique 20100101

Comparison of antiviral activity of recombinant and natural interferons against crimean-congo hemorrhagic Fever virus.

The open virology journal 20100101

Sex differences in dopamine D2-like receptor-mediated G-protein activation in the medial prefrontal cortex after cocaine.

Ethnicity & disease 20100101

RS-1748, a novel CC chemokine receptor 4 antagonist, inhibits ovalbumin-induced airway inflammation in guinea pigs.

Biological & pharmaceutical bulletin 20100101

Update on the clinical utility of sildenafil in the treatment of pulmonary arterial hypertension.

Drug design, development and therapy 20100101

Transdermal nitroglycerine enhances postoperative analgesia of intrathecal neostigmine following abdominal hysterectomies.

Indian journal of anaesthesia 20100101

Structural and dynamical effects induced by the anticancer drug topotecan on the human topoisomerase I - DNA complex.

PloS one 20100101

Q344ter mutation causes mislocalization of rhodopsin molecules that are catalytically active: a mouse model of Q344ter-induced retinal degeneration.

PloS one 20100101

Extracellular ATP and the P2X7 receptor in astrocyte-mediated motor neuron death: implications for amyotrophic lateral sclerosis.

Journal of neuroinflammation 20100101

Innate immune recognition and activation during HIV infection.

Retrovirology 20100101

Detection and analysis of alternative splicing in Yarrowia lipolytica reveal structural constraints facilitating nonsense-mediated decay of intron-retaining transcripts.

Genome biology 20100101

High-affinity consensus binding of target RNAs by the STAR/GSG proteins GLD-1, STAR-2 and Quaking.

BMC molecular biology 20100101

Alu sequences in undifferentiated human embryonic stem cells display high levels of A-to-I RNA editing.

PloS one 20100101

Study of the nitric oxide system in the rat cerebellum during aging.

BMC neuroscience 20100101

Impact of RNA editing on functions of the serotonin 2C receptor in vivo.

Frontiers in neuroscience 20100101

Cell type mediated resistance of vesicular stomatitis virus and Sendai virus to ribavirin.

PloS one 20100101

Live recombinant Salmonella Typhi vaccines constructed to investigate the role of rpoS in eliciting immunity to a heterologous antigen.

PloS one 20100101

Subcutaneous Sarcoidosis during Pegylated Interferon Alfa and Ribavirin Treatment for Chronic Hepatitis C.

Dermatology research and practice 20100101

N-methyl-aspartate receptor and neuronal nitric oxide synthase activation mediate bilirubin-induced neurotoxicity.

Molecular medicine (Cambridge, Mass.) 20100101

[Continuing investigation of effect of toner and its by-product on human health and occupational health management of toner].

Sangyo eiseigaku zasshi = Journal of occupational health 20100101

RNA vaccines in cancer treatment.

Journal of biomedicine & biotechnology 20100101

A liquid chromatographic method for routine analysis of 5'-mononucleotides in pediatric formulas.

Journal of AOAC International 20100101

Endothelial dysfunction, inflammation, and apoptosis in diabetes mellitus.

Mediators of inflammation 20100101

PAR-CliP--a method to identify transcriptome-wide the binding sites of RNA binding proteins.

Journal of visualized experiments : JoVE 20100101

Complete mitochondrial genomes of Taenia multiceps, T. hydatigena and T. pisiformis: additional molecular markers for a tapeworm genus of human and animal health significance.

BMC genomics 20100101

Adipocytokines in atherothrombosis: focus on platelets and vascular smooth muscle cells.

Mediators of inflammation 20100101

Identification of pathway-biased and deleterious melatonin receptor mutants in autism spectrum disorders and in the general population.

PloS one 20100101

Large-scale analysis of structural, sequence and thermodynamic characteristics of A-to-I RNA editing sites in human Alu repeats.

BMC genomics 20100101

Effects of GCK, GCKR, G6PC2 and MTNR1B variants on glucose metabolism and insulin secretion.

PloS one 20100101

Immunomodulatory effects of dsRNA and its potential as vaccine adjuvant.

Journal of biomedicine & biotechnology 20100101

Archaea signal recognition particle shows the way.

Archaea (Vancouver, B.C.) 20100101

Oscillations by minimal bacterial suicide circuits reveal hidden facets of host-circuit physiology.

PloS one 20100101

Methylated APC and GSTP1 genes in serum DNA correlate with the presence of circulating blood tumor cells and are associated with a more aggressive and advanced breast cancer disease.

European journal of medical research 20100101

Candida albicans AGE3, the ortholog of the S. cerevisiae ARF-GAP-encoding gene GCS1, is required for hyphal growth and drug resistance.

PloS one 20100101

Long-Term Impact of Cyclosporin Reduction with MMF Treatment in Chronic Allograft Dysfunction: REFERENECE Study 3-Year Follow Up.

Journal of transplantation 20100101

Effect of base sequence on g-wire formation in solution.

Journal of nucleic acids 20100101

Guanosine quadruplexes in solution: a small-angle x-ray scattering analysis of temperature effects on self-assembling of deoxyguanosine monophosphate.

Journal of nucleic acids 20100101

A toolbox for predicting g-quadruplex formation and stability.

Journal of nucleic acids 20100101

Specificity of methylation assays in cancer research: a guideline for designing primers and probes.

Obstetrics and gynecology international 20100101

Integrating GHS into the Ghrelin System.

International journal of peptides 20100101

Hierarchical formation of fibrillar and lamellar self-assemblies from guanosine-based motifs.

Journal of nucleic acids 20100101

Protection effect of taurine on nitrosative stress in the mice brain with chronic exposure to arsenic.

Journal of biomedical science 20100101

Antimalarial drug targets in Plasmodium falciparum predicted by stage-specific metabolic network analysis.

BMC systems biology 20100101

Spatial regulation of membrane fusion controlled by modification of phosphoinositides.

PloS one 20100101

Overexpression of inosine 5'-monophosphate dehydrogenase type II mediates chemoresistance to human osteosarcoma cells.

PloS one 20100101

Template-directed ligation of tethered mononucleotides by t4 DNA ligase for kinase ribozyme selection.

PloS one 20100101

Cytidine-Ag+-purine base complexes as studied by electrospray ionization mass spectrometry.

European journal of mass spectrometry (Chichester, England) 20100101

G-quadruplex nucleic acids.

Journal of nucleic acids 20100101

Epigenetics of renal cell carcinoma: the path towards new diagnostics and therapeutics.

Genome medicine 20100101

The genome of Geobacter bemidjiensis, exemplar for the subsurface clade of Geobacter species that predominate in Fe(III)-reducing subsurface environments.

BMC genomics 20100101

Transfer RNA modifications and genes for modifying enzymes in Arabidopsis thaliana.

BMC plant biology 20100101

Guanosine protects human neuroblastoma cells from oxidative stress and toxicity induced by Amyloid-beta peptide oligomers.

Journal of biological regulators and homeostatic agents 20100101

Selenocysteine, pyrrolysine, and the unique energy metabolism of methanogenic archaea.

Archaea (Vancouver, B.C.) 20100101

Toll-like receptors: role in dermatological disease.

Mediators of inflammation 20100101

MPF governs the assembly and contraction of actomyosin rings by activating RhoA and MAPK during chemical-induced cytokinesis of goat oocytes.

PloS one 20100101

Pulmonary vascular and right ventricular dysfunction in adult critical care: current and emerging options for management: a systematic literature review.

Critical care (London, England) 20100101

Crystal structure of the dengue virus methyltransferase bound to a 5'-capped octameric RNA.

PloS one 20100101

Early combined treatment with sildenafil and adipose-derived mesenchymal stem cells preserves heart function in rat dilated cardiomyopathy.

Journal of translational medicine 20100101

Gut inflammation in chronic fatigue syndrome.

Nutrition & metabolism 20100101

Can physical stress be measured in urine using the parameter antioxidative potential?

GMS Krankenhaushygiene interdisziplinar 20100101

Comparison of selected cryoprotective agents to stabilize meiotic spindles of human oocytes during cooling.

Journal of experimental & clinical assisted reproduction 20100101

Recent advances in management of bladder overactivity.

F1000 medicine reports 20100101

Consistent levels of A-to-I RNA editing across individuals in coding sequences and non-conserved Alu repeats.

BMC genomics 20100101

Effects of mycophenolate mofetil on proliferation and mucin-5AC expression in human conjunctival goblet cells in vitro.

Molecular vision 20100101

Detecting constitutive activity and protean agonism at cannabinoid-2 receptor.

Methods in enzymology 20100101

Constitutive activity of GPR40/FFA1 intrinsic or assay dependent?

Methods in enzymology 20100101

Analysis of Monosodium l-Glutamate in Food Products by High-Performance Thin Layer Chromatography.

Journal of young pharmacists : JYP 20100101

Measurement of inverse agonism of the cannabinoid receptors.

Methods in enzymology 20100101

Methods to measure g-protein-coupled receptor activity for the identification of inverse agonists.

Methods in enzymology 20100101

Fusion proteins as model systems for the analysis of constitutive GPCR activity.

Methods in enzymology 20100101

Coexpression systems as models for the analysis of constitutive GPCR activity.

Methods in enzymology 20100101

Effects of inosine on reperfusion injury after cardiopulmonary bypass.

Journal of cardiothoracic surgery 20100101

Substitutional A-to-I RNA editing.

Wiley interdisciplinary reviews. RNA 20100101

Inhibition of core gene of HCV 3a genotype using synthetic and vector derived siRNAs.

Virology journal 20100101

RhoA regulates peroxisome association to microtubules and the actin cytoskeleton.

PloS one 20100101

Zinc in innate and adaptive tumor immunity.

Journal of translational medicine 20100101

An empirical Bayes model for gene expression and methylation profiles in antiestrogen resistant breast cancer.

BMC medical genomics 20100101

Differential proteomic analysis highlights metabolic strategies associated with balhimycin production in Amycolatopsis balhimycina chemostat cultivations.

Microbial cell factories 20100101

PARP1 gene knock-out increases resistance to retinal degeneration without affecting retinal function.

PloS one 20100101

Neuroprotective properties of mildronate, a small molecule, in a rat model of Parkinson's disease.

International journal of molecular sciences 20100101

Identification, activity and disulfide connectivity of C-di-GMP regulating proteins in Mycobacterium tuberculosis.

PloS one 20100101

The N-terminus of GalE induces tmRNA activity in Escherichia coli.

PloS one 20100101

Expression and regulation of cyclic nucleotide phosphodiesterases in human and rat pancreatic islets.

PloS one 20100101

Clinical effectiveness of telmisartan alone or in combination therapy for controlling blood pressure and vascular risk in the elderly.

Clinical interventions in aging 20100101

Mechanistic and functional versatility of radical SAM enzymes.

F1000 biology reports 20100101

Comparative proteomic analysis of Salmonella enterica serovar Typhimurium ppGpp-deficient mutant to identify a novel virulence protein required for intracellular survival in macrophages.

BMC microbiology 20100101

Caffeine's Vascular Mechanisms of Action.

International journal of vascular medicine 20100101

Amyloid-β inhibits No-cGMP signaling in a CD36- and CD47-dependent manner.

PloS one 20100101

The biological and metabolic fates of endogenous DNA damage products.

Journal of nucleic acids 20100101

Formation and repair of tobacco carcinogen-derived bulky DNA adducts.

Journal of nucleic acids 20100101

Towards a systems approach in the genetic analysis of archaea: Accelerating mutant construction and phenotypic analysis in Haloferax volcanii.

Archaea (Vancouver, B.C.) 20100101

Recent advancements in toxin and antitoxin systems involved in bacterial programmed cell death.

International journal of microbiology 20100101

Experimental models of duchenne muscular dystrophy: relationship with cardiovascular disease.

The open cardiovascular medicine journal 20100101

Insights into the development and treatment of cardiovascular disease: a role for animal models.

The open cardiovascular medicine journal 20100101

Glycoxidative stress and cardiovascular complications in experimentally-induced diabetes: effects of antioxidant treatment.

The open cardiovascular medicine journal 20100101

Mammalian target of rapamycin: hitting the bull's-eye for neurological disorders.

Oxidative medicine and cellular longevity 20100101

A rapid, inexpensive high throughput screen method for neurite outgrowth.

Current chemical genomics 20100101

Platelets and cardiac arrhythmia.

Frontiers in physiology 20100101

The NO-cGMP-PKG signaling pathway coordinately regulates ERK and ERK-driven gene expression at pre- and postsynaptic sites following LTP-inducing stimulation of thalamo-amygdala synapses.

Neural plasticity 20100101

An assay for measuring the activity of Escherichia coli inducible lysine decarboxylase.

Journal of visualized experiments : JoVE 20100101

Dendritic spines and development: towards a unifying model of spinogenesis--a present day review of Cajal's histological slides and drawings.

Neural plasticity 20100101

Are antioxidants helpful for disease prevention?

Research in pharmaceutical sciences 20100101

Screening and initial binding assessment of fumonisin b(1) aptamers.

International journal of molecular sciences 20100101

GIMAP Proteins in T-Lymphocytes.

Journal of signal transduction 20100101

Two phosphodiesterases from ustilago maydis share structural and biochemical properties with non-fungal phosphodiesterases.

Frontiers in microbiology 20100101

Role of tacrolimus combination therapy with mycophenolate mofetil in the prevention of organ rejection in kidney transplant patients.

International journal of nephrology and renovascular disease 20100101

Safety and tolerability of zoledronic acid and other bisphosphonates in osteoporosis management.

Drug, healthcare and patient safety 20100101

Design strategies of fluorescent biosensors based on biological macromolecular receptors.

Sensors (Basel, Switzerland) 20100101

The comparative efficacy and safety of peginterferon alpha-2a vs. 2b for the treatment of chronic HCV infection: a meta-analysis.

Hepatitis monthly 20100101

Interferon-alpha induced and ribavirin induced thyroid dysfunction in patients with chronic hepatitis C.

Hepatitis monthly 20100101

Oxidant sensing by protein kinases a and g enables integration of cell redox state with phosphoregulation.

Sensors (Basel, Switzerland) 20100101

Classification of g-quadruplex DNA on the basis of the quadruplex twist angle and planarity of g-quartets.

Acta naturae 20100101

Solvent effects on ionization potentials of guanine runs and chemically modified guanine in duplex DNA: effect of electrostatic interaction and its reduction due to solvent.

The journal of physical chemistry. B 20091224

Ultrashort fluorescence lifetimes of hydrogen-bonded base pairs of guanosine and cytidine in solution.

The journal of physical chemistry. B 20091224

Modulating unimolecular charge transfer by exciting bridge vibrations.

Journal of the American Chemical Society 20091223

Adenosine deamination in human transcripts generates novel microRNA binding sites.

Human molecular genetics 20091215

Functional characterization of intracellular Dictyostelium discoideum P2X receptors.

The Journal of biological chemistry 20091211

The structural basis for mRNA recognition and cleavage by the ribosome-dependent endonuclease RelE.

Cell 20091211

Synthesis and optical properties of guanosine 5'-monophosphate-mediated CdS nanostructures: an analysis of their structure, morphology, and electronic properties.

Inorganic chemistry 20091207

A recombination hot spot in HIV-1 contains guanosine runs that can form a G-quartet structure and promote strand transfer in vitro.

The Journal of biological chemistry 20091204

Kidney disease in nail-patella syndrome.

Pediatric nephrology (Berlin, Germany) 20091201

Influence of tunable external stimuli on the self-assembly of guanosine supramolecular nanostructures studied by atomic force microscope.

Langmuir : the ACS journal of surfaces and colloids 20091201

Resistance patterns and detection of aac(3)-IV gene in apramycin-resistant Escherichia coli isolated from farm animals and farm workers in northeastern of China.

Research in veterinary science 20091201

Dysregulation of glucose homeostasis in nicotinamide nucleotide transhydrogenase knockout mice is independent of uncoupling protein 2.

Biochimica et biophysica acta 20091201

Guanosine-5'-monophosphate induces cell death in rat hippocampal slices via ionotropic glutamate receptors activation and glutamate uptake inhibition.

Neurochemistry international 20091201

Follicle development and luteal cell morphology altered by phosphodiesterase-5 inhibitor.

Micron (Oxford, England : 1993) 20091201

Modulation of guanosine 5'-diphosphate-D-mannose metabolism in recombinant Escherichia coli for production of guanosine 5'-diphosphate-L-fucose.

Bioresource technology 20091201

Modulating RNA structure and catalysis: lessons from small cleaving ribozymes.

Cellular and molecular life sciences : CMLS 20091201

Opioid use affects antioxidant activity and purine metabolism: preliminary results.

Human psychopharmacology 20091201

20-125Iodo-14,15-epoxyeicosa-5(Z)-enoic acid: a high-affinity radioligand used to characterize the epoxyeicosatrienoic acid antagonist binding site.

The Journal of pharmacology and experimental therapeutics 20091201

Functional autoradiography and gene expression analysis applied to the characterization of the alpha2-adrenergic system in the chicken brain.

Journal of chemical neuroanatomy 20091201

The R1441C mutation alters the folding properties of the ROC domain of LRRK2.

Biochimica et biophysica acta 20091201

The rho guanosine 5'-triphosphatase, cell division cycle 42, is required for insulin-induced actin remodeling and glucagon-like peptide-1 secretion in the intestinal endocrine L cell.

Endocrinology 20091201

Nemo-like kinase is involved in NGF-induced neurite outgrowth via phosphorylating MAP1B and paxillin.

Journal of neurochemistry 20091201

Reinforcing feedback loop of renal cyclic guanosine 3' 5' -monophosphate and interstitial hydrostatic pressure in pressure-natriuresis.

Hypertension (Dallas, Tex. : 1979) 20091201

Free energy calculation of modified base-pair formation in explicit solvent: A predictive model.

RNA (New York, N.Y.) 20091201

Guanosine-induced synaptogenesis in the adult brain in vivo.

Anatomical record (Hoboken, N.J. : 2007) 20091201

The FAS -670A>G polymorphism influences susceptibility to systemic sclerosis phenotypes.

Arthritis and rheumatism 20091201

Protein kinase G controls brown fat cell differentiation and mitochondrial biogenesis.

Science signaling 20091201

Nonenzymatic oligomerization of activated nucleotides on hairpin templates.

Current protocols in nucleic acid chemistry 20091201

[Clinical efficacy of entecavir therapy and factors associated with treatment response in naive chronic hepatitis B patients].

The Korean journal of hepatology 20091201

Three dimensional structure of the MqsR:MqsA complex: a novel TA pair comprised of a toxin homologous to RelE and an antitoxin with unique properties.

PLoS pathogens 20091201

Recent insights into the mechanisms of vasospastic angina.

Korean circulation journal 20091201

N-terminal pro-B-type natriuretic Peptide in overweight and obese patients with and without diabetes: an analysis based on body mass index and left ventricular geometry.

Korean circulation journal 20091201

Relaxation patterns of human gastric corporal smooth muscle by cyclic nucleotides producing agents.

The Korean journal of physiology & pharmacology : official journal of the Korean Physiological Society and the Korean Society of Pharmacology 20091201

HBV and HCV therapy.

Viruses 20091201

Hydration structures of 2'-deoxyguanosine studied by IR-UV double resonance spectroscopy: comparison with guanosine.

Physical chemistry chemical physics : PCCP 20091128

RelB and RelE of Escherichia coli form a tight complex that represses transcription via the ribbon-helix-helix motif in RelB.

Journal of molecular biology 20091127

Nonpolymeric thermosensitive supramolecules.

Journal of the American Chemical Society 20091125

The GTPase activity of Escherichia coli FtsZ determines the magnitude of the FtsZ polymer bundling by ZapA in vitro.

Biochemistry 20091124

Guanosine + OH radical reaction in aqueous solution: a reinterpretation of the UV-vis data based on thermodynamic and kinetic calculations.

Organic letters 20091119

Direct chemiluminescence detection of nitric oxide in aqueous solutions using the natural nitric oxide target soluble guanylyl cyclase.

Free radical biology & medicine 20091115

A supramolecular Cu(II) metallocyclophane probe for guanosine 5'-monophosphate.

Chemical communications (Cambridge, England) 20091114

Probing the catalytic sites and activation mechanism of photoreceptor phosphodiesterase using radiolabeled phosphodiesterase inhibitors.

The Journal of biological chemistry 20091113

Toll-like receptor 7 selective synthetic oligoribonucleotide agonists: synthesis and structure-activity relationship studies.

Journal of medicinal chemistry 20091112

Structural evidence for a sequential release mechanism for activation of heterotrimeric G proteins.

Journal of molecular biology 20091106

Enhanced DNA binding capacity on up-regulated epidermal wild-type p53 in vitiligo by H2O2-mediated oxidation: a possible repair mechanism for DNA damage.

FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20091101

Evaluation of the antipsychotic effect of bi-acetylated l-stepholidine (l-SPD-A), a novel dopamine and serotonin receptor dual ligand.

Schizophrenia research 20091101

Exercise activates redox-sensitive transcription factors and restores renal D1 receptor function in old rats.

American journal of physiology. Renal physiology 20091101

Trp fluorescence reveals an activation-dependent cation-pi interaction in the Switch II region of Galphai proteins.

Protein science : a publication of the Protein Society 20091101

Betulin-derived compounds as inhibitors of alphavirus replication.

Journal of natural products 20091101

Sources of extracellular, oxidatively-modified DNA lesions: implications for their measurement in urine.

Journal of clinical biochemistry and nutrition 20091101

Synthesis of guanosine and deoxyguanosine phosphoramidites with cross-linkable thioalkyl tethers for direct incorporation into RNA and DNA.

Nucleosides, nucleotides & nucleic acids 20091101

An atypical CNG channel activated by a single cGMP molecule controls sperm chemotaxis.

Science signaling 20091027

Transmembrane protein-free membranes fuse into xenopus nuclear envelope and promote assembly of functional pores.

The Journal of biological chemistry 20091023

Editing independent effects of ADARs on the miRNA/siRNA pathways.

The EMBO journal 20091021

Random amplified polymorphic DNA (RAPD) analysis and the nucleosides assessment of fungal strains isolated from natural Cordyceps sinensis.

Journal of pharmaceutical and biomedical analysis 20091015

Determination of nucleosides and nucleobases in different species of Cordyceps by capillary electrophoresis-mass spectrometry.

Journal of pharmaceutical and biomedical analysis 20091015

Efficient and rapid template-directed nucleic acid copying using 2'-amino-2',3'-dideoxyribonucleoside-5'-phosphorimidazolide monomers.

Journal of the American Chemical Society 20091014

Dopamine gene therapy for Parkinson's disease in a nonhuman primate without associated dyskinesia.

Science translational medicine 20091014

A potentially versatile nucleotide hydrolysis activity of group II chaperonin monomers from Thermoplasma acidophilum.

Biochemistry 20091013

Hard/soft selectivity in ligand substitution reactions of beta-diketonate platinum(II) complexes.

Dalton transactions (Cambridge, England : 2003) 20091007

The mammalian sympathetic prevertebral ganglia: models for the study of neuronal networks and basic neuronal properties.

Autonomic neuroscience : basic & clinical 20091005

Inhibition of tumour necrosis factor and IL-17 production by leflunomide involves the JAK/STAT pathway.

Annals of the rheumatic diseases 20091001

Potential therapeutic advantages of guanosine over inosine in multiple sclerosis.

Medical hypotheses 20091001

The dopaminergic stabilizer ASP2314/ACR16 selectively interacts with D2(High) receptors.

Synapse (New York, N.Y.) 20091001

Glutamate agonist LY404,039 for treating schizophrenia has affinity for the dopamine D2(High) receptor.

Synapse (New York, N.Y.) 20091001

Rac1 is required for cardiomyocyte apoptosis during hyperglycemia.

Diabetes 20091001

Mutant 5-hydroxytryptamine 1A receptor D116A is a receptor activated solely by synthetic ligands with a rich pharmacology.

The Journal of pharmacology and experimental therapeutics 20091001

The (p)ppGpp synthetase RelA contributes to stress adaptation and virulence in Enterococcus faecalis V583.

Microbiology (Reading, England) 20091001

Functional characterization of two isoforms of the P2Y-like receptor GPR17: [35S]GTPgammaS binding and electrophysiological studies in 1321N1 cells.

American journal of physiology. Cell physiology 20091001

Phosphodiesterase type 5 inhibitors facilitate noncontact erections in male rats: site of action in the brain and mechanism of action.

The journal of sexual medicine 20091001

CXCR2 inverse agonism detected by arrestin redistribution.

Journal of biomolecular screening 20091001

Molecular gate keepers succumb to gene aberrations in colorectal cancer in Kashmiri population, revealing a high incidence area.

Saudi journal of gastroenterology : official journal of the Saudi Gastroenterology Association 20091001

Kissing G domains of MnmE monitored by X-ray crystallography and pulse electron paramagnetic resonance spectroscopy.

PLoS biology 20091001

EBNA1-mediated recruitment of a histone H2B deubiquitylating complex to the Epstein-Barr virus latent origin of DNA replication.

PLoS pathogens 20091001

Cloning and characterization of the rhesus monkey nociceptin/orphanin FQ receptor.

Genes & genetic systems 20091001

Synthesis of 3'-amino-3'-deoxyguanosine and 3'-amino-3'-deoxyxyloguanosine monophosphate HepDirect prodrugs from guanosine.

Nucleosides, nucleotides & nucleic acids 20091001

Purification and functional reconstitution of monomeric mu-opioid receptors: allosteric modulation of agonist binding by Gi2.

The Journal of biological chemistry 20090925

Leucyl-tRNA synthetase-dependent and -independent activation of a group I intron.

The Journal of biological chemistry 20090925

Pertussis toxin-sensitive signaling of melanocortin-4 receptors in hypothalamic GT1-7 cells defines agouti-related protein as a biased agonist.

The Journal of biological chemistry 20090925

Co-administration of the partial dopamine D2 agonist terguride with L-dopa attenuates L-dopa-induced locomotor sensitization in hemiparkinsonian mice.

Behavioural brain research 20090914

Manifestations of the mitochondrial A3243G mutation.

International journal of cardiology 20090911

Supramolecular structure and polymorphism of alkali metal salts of guanosine 5'-monophosphate: SEM and NMR study.

The journal of physical chemistry. B 20090910

Aqueous methods for the preparation of 5'-substituted guanosine derivatives.

Chemical communications (Cambridge, England) 20090907

Rigid rod and tetrahedral hybrid compounds featuring nucleobase and nucleoside end-capped structures.

Organic & biomolecular chemistry 20090907

Activation of protease calpain by oxidized and glycated LDL increases the degradation of endothelial nitric oxide synthase.

Journal of cellular and molecular medicine 20090901

Advances in preclinical therapeutics development using small animal imaging and molecular analyses: the gastrointestinal stromal tumors model.

Clinical and experimental medicine 20090901

The phosphorylation status of membrane-bound nucleoside diphosphate kinase in epithelia and the role of AMP.

Molecular and cellular biochemistry 20090901

Nucleoside diphosphate kinase (NDPK, NM23, AWD): recent regulatory advances in endocytosis, metastasis, psoriasis, insulin release, fetal erythroid lineage and heart failure; translational medicine exemplified.

Molecular and cellular biochemistry 20090901

DNA interactions and photocatalytic strand cleavage by artificial nucleases based on water-soluble gold(III) porphyrins.

Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry 20090901

Exploring the mechanism of agonist efficacy: a relationship between efficacy and agonist dissociation rate at the muscarinic M3 receptor.

Molecular pharmacology 20090901

Synthesis, characterization, and reaction pathways for the formation of a GMP adduct of a cytotoxic thiocyanato ruthenium arene complex.

Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry 20090901

Folate intake and bowel cancer risk.

Genes & nutrition 20090901

Automated method for the direct analysis of 8-oxo-guanosine and 8-oxo-2'-deoxyguanosine in human urine using ultraperformance liquid chromatography and tandem mass spectrometry.

Free radical biology & medicine 20090901

Effect of (r)-9-[4-hydroxy-2-(hydroxymethyl)butyl]guanine (H2G) and AZT-lipid-PFA on human herpesvirus-6B infected cells.

Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology 20090901

GDI-1 preferably interacts with Rab10 in insulin-stimulated GLUT4 translocation.

The Biochemical journal 20090901

Potential roles of melatonin and chronotherapy among the new trends in hypertension treatment.

Journal of pineal research 20090901

Molecular and cellular regulation of pancreatic acinar cell function.

Current opinion in gastroenterology 20090901

Temporal lobe epilepsy causes selective changes in mu opioid and nociceptin receptor binding and functional coupling to G-proteins in human temporal neocortex.

Neurobiology of disease 20090901

Measurement of one and two bond N-C couplings in large proteins by TROSY-based J-modulation experiments.

Journal of magnetic resonance (San Diego, Calif. : 1997) 20090901

Molecularly imprinted monolith in-tube solid-phase microextraction coupled with HPLC/UV detection for determination of 8-hydroxy-2'-deoxyguanosine in urine.

Analytical and bioanalytical chemistry 20090901

Development and validation of a gas chromatography/mass spectrometry method for the assessment of genomic DNA methylation.

Rapid communications in mass spectrometry : RCM 20090901

Novel delta opioid receptor agonists exhibit differential stimulation of signaling pathways.

Bioorganic & medicinal chemistry 20090901

Formation of spiroiminodihydantoin nucleoside from 8-oxo-7,8-dihydro-2'-deoxyguanosine by nitric oxide under aerobic conditions.

Bioorganic & medicinal chemistry letters 20090901

Can we improve outcome of congenital diaphragmatic hernia?

Pediatric surgery international 20090901

Weak toxin WTX from Naja kaouthia cobra venom interacts with both nicotinic and muscarinic acetylcholine receptors.

The FEBS journal 20090901

Towards a new understanding on the regulation of mammalian oocyte meiosis resumption.

Cell cycle (Georgetown, Tex.) 20090901

Mu opioid receptor from the zebrafish exhibits functional characteristics as those of mammalian mu opioid receptor.

Zebrafish 20090901

A cyclic GMP signalling module that regulates gliding motility in a malaria parasite.

PLoS pathogens 20090901

Marine-derived metabolites of S-adenosylmethionine as templates for new anti-infectives.

Marine drugs 20090901

[Chemical constituents of Momordica charantia L].

Yao xue xue bao = Acta pharmaceutica Sinica 20090901

Release of adenosine and ATP during ischemia and epilepsy.

Current neuropharmacology 20090901

Oxidation of the carcinogenic non-aminoazo dye 1-phenylazo-2-hydroxy-naphthalene (Sudan I) by cytochromes P450 and peroxidases: a comparative study.

Interdisciplinary toxicology 20090901

Recruitment of the earliest component of the bacterial flagellum to the old cell division pole by a membrane-associated signal recognition particle family GTP-binding protein.

Journal of molecular biology 20090828

Evolution of ribozymes in an RNA world.

Chemistry & biology 20090828

A promiscuous ribozyme promotes nucleotide synthesis in addition to ribose chemistry.

Chemistry & biology 20090828

Anion exchange liquid chromatography for the determination of nucleotides in baby and/or functional foods.

Journal of agricultural and food chemistry 20090826

Inhibition of inosine monophosphate dehydrogenase reduces adipogenesis and diet-induced obesity.

Biochemical and biophysical research communications 20090821

Pd(0)/Cu(I)-mediated direct arylation of 2'-deoxyadenosines: mechanistic role of Cu(I) and reactivity comparisons with related purine nucleosides.

The Journal of organic chemistry 20090821

Activating mu-opioid receptors in the lateral parabrachial nucleus increases c-Fos expression in forebrain areas associated with caloric regulation, reward and cognition.

Neuroscience 20090818

Identification of cell culture conditions to control N-glycosylation site-occupancy of recombinant glycoproteins expressed in CHO cells.

Biotechnology and bioengineering 20090815

Synthesis and characterization of modified nucleotides in the 970 hairpin loop of Escherichia coli 16S ribosomal RNA.

Bioorganic & medicinal chemistry 20090815

Immobilization of self-quenched DNA hairpin probe with a heterobifunctional reagent on a glass surface for sensitive detection of oligonucleotides.

Bioorganic & medicinal chemistry 20090815

Synaptotagmin-like protein 1 interacts with the GTPase-activating protein Rap1GAP2 and regulates dense granule secretion in platelets.

Blood 20090813

Triazole inhibitors of Cryptosporidium parvum inosine 5'-monophosphate dehydrogenase.

Journal of medicinal chemistry 20090813

Guanosine hydrogen-bonded scaffolds: a new way to control the bottom-up realisation of well-defined nanoarchitectures.

Chemistry (Weinheim an der Bergstrasse, Germany) 20090810

Walking a supramolecular tightrope: a self-assembled dodecamer from an 8-aryl-2'-deoxyguanosine derivative.

Journal of the American Chemical Society 20090805

Structural and functional analysis of Sulfolobus solfataricus Y-family DNA polymerase Dpo4-catalyzed bypass of the malondialdehyde-deoxyguanosine adduct.

Biochemistry 20090804

Evidence for action of ribavirin through the hepatitis C virus RNA polymerase.

Journal of viral hepatitis 20090801

Complex plastic changes in the neuropeptide Y system during ethanol intoxication and withdrawal in the rat brain.

Journal of neuroscience research 20090801

Estradiol increases guanosine 5'-triphosphate cyclohydrolase expression via the nitric oxide-mediated activation of cyclic adenosine 5'-monophosphate response element binding protein.

Endocrinology 20090801

Magic spot: (p) ppGpp.

Journal of cellular physiology 20090801

Dopamine D2High receptors stimulated by phencyclidines, lysergic acid diethylamide, salvinorin A, and modafinil.

Synapse (New York, N.Y.) 20090801

Altered M(1) muscarinic acetylcholine receptor (CHRM1)-Galpha(q/11) coupling in a schizophrenia endophenotype.

Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20090801

Abstracts of the 2008 ISSOL Meeting. August 24-29, 2008. Florence, Italy.

Origins of life and evolution of the biosphere : the journal of the International Society for the Study of the Origin of Life 20090801

Sphingosine-1-phosphate receptors mediate neuromodulatory functions in the CNS.

Journal of neurochemistry 20090801

Fe(II) phthalocyanine catalyzed oxidation of dGMP by molecular oxygen.

Bioorganic & medicinal chemistry letters 20090801

The phosphoramidate ProTide approach greatly enhances the activity of beta-2'-C-methylguanosine against hepatitis C virus.

Bioorganic & medicinal chemistry letters 20090801

In vivo activation of AMP-activated protein kinase attenuates diabetes-enhanced degradation of GTP cyclohydrolase I.

Diabetes 20090801

A fast capillary electrophoresis method for separation and quantification of modified nucleosides in urinary samples.

Analytical chemistry 20090801

Structure of RNase Sa2 complexes with mononucleotides--new aspects of catalytic reaction and substrate recognition.

The FEBS journal 20090801

Toll-like receptor 7 and 9 defects in common variable immunodeficiency.

The Journal of allergy and clinical immunology 20090801

Cyclic adenosine monophosphate (cAMP)-specific phosphodiesterase is functional in bovine mammary gland.

Journal of dairy science 20090801

Preclinical assessment of the treatment of second-stage African trypanosomiasis with cordycepin and deoxycoformycin.

PLoS neglected tropical diseases 20090801

Genome-wide scan of 500,000 single-nucleotide polymorphisms among responders and nonresponders to interferon beta therapy in multiple sclerosis.

Archives of neurology 20090801

Relationship of urinary cGMP excretion with aging and menopausal status in a general population.

Journal of atherosclerosis and thrombosis 20090801

Persistent cAMP-signals triggered by internalized G-protein-coupled receptors.

PLoS biology 20090801

Autocatalytic loop, amplification and diffusion: a mathematical and computational model of cell polarization in neural chemotaxis.

PLoS computational biology 20090801

[Umbilical cord plasma endothelin 1 and cyclic guanosine concentrations monophosphate at delivery in pregnancy complicated by diabetes mellitus].

Ginekologia polska 20090801

A new odorless procedure for the synthesis of 2'-deoxy-6-thioguanosine and its incorporation into oligodeoxynucleotides.

Nucleosides, nucleotides & nucleic acids 20090801

Role of the general base Glu-268 in nitroglycerin bioactivation and superoxide formation by aldehyde dehydrogenase-2.

The Journal of biological chemistry 20090724

Structural interpretation of J coupling constants in guanosine and deoxyguanosine: modeling the effects of sugar pucker, backbone conformation, and base pairing.

The journal of physical chemistry. A 20090723

Ars2 links the nuclear cap-binding complex to RNA interference and cell proliferation.

Cell 20090723

A simple method for C-6 modification of guanine nucleosides.

Organic & biomolecular chemistry 20090721

ENDOR spectroscopy shows that guanine N1 binds to [4Fe-4S] cluster II of the S-adenosylmethionine-dependent enzyme MoaA: mechanistic implications.

Journal of the American Chemical Society 20090708

DNA repair and DNA triplet repeat expansion: the impact of abasic lesions on triplet repeat DNA energetics.

Journal of the American Chemical Society 20090708

Insulin action on polyunsaturated phosphatidic acid formation in rat brain: an 'in vitro' model with synaptic endings from cerebral cortex and hippocampus.

Neurochemical research 20090701

Palmitoylation modification of Galpha(o) depresses its susceptibility to GAP-43 activation.

The international journal of biochemistry & cell biology 20090701

Effects of the NO donor sodium nitroprusside on oxygen consumption and energetics in rabbit myocardium.

Basic research in cardiology 20090701

Another ten stories in antiviral drug discovery (part C): 'Old' and 'new' antivirals, strategies, and perspectives.

Medicinal research reviews 20090701

RNA oxidation in Alzheimer disease and related neurodegenerative disorders.

Acta neuropathologica 20090701

Increase of uric acid and purine compounds in biological fluids of multiple sclerosis patients.

Clinical biochemistry 20090701

Delta receptors are required for full inhibitory coupling of mu-receptors to voltage-dependent Ca(2+) channels in dorsal root ganglion neurons.

Molecular pharmacology 20090701

Biochemical characterisation of the D60A mutant of the elongation factor 1alpha from the archaeon Sulfolobus solfataricus.

Biochimie 20090701

Activation switch in the transmembrane domain of metabotropic glutamate receptor.

Molecular pharmacology 20090701

The signal pathway of gonadotrophins-induced mammalian oocyte meiotic resumption.

Molecular human reproduction 20090701

Pharmacological characterization of the nociceptin/orphanin FQ receptor non peptide antagonist Compound 24.

European journal of pharmacology 20090701

Influence of nucleotide identity on ribose 2'-hydroxyl reactivity in RNA.

RNA (New York, N.Y.) 20090701

Efficient solid-phase synthesis of oligodeoxynucleotides having a 5'-terminal 2,2,7-trimethylguanosine pyrophosphate linkage.

Bioorganic & medicinal chemistry 20090701

Origin of an alternative genetic code in the extremely small and GC-rich genome of a bacterial symbiont.

PLoS genetics 20090701

Effect of food on the pharmacokinetics of the oral phosphodiesterase 5 inhibitor udenafil for the treatment of erectile dysfunction.

British journal of clinical pharmacology 20090701

Phosphodiesterase 3 (PDE3): structure, localization and function.

Cardiovascular & hematological agents in medicinal chemistry 20090701

Applications of isothermal titration calorimetry in biophysical studies of G-quadruplexes.

International journal of molecular sciences 20090701

Mycophenolate mofetil: An update.

Drugs of today (Barcelona, Spain : 1998) 20090701

New approaches for cancer treatment: antitumor drugs based on gene-targeted nucleic acids.

Acta naturae 20090701

Identification and characterization of a novel lysophosphatidic acid receptor, p2y5/LPA6.

The Journal of biological chemistry 20090626

The action and mode of binding of thiazolidinedione ligands at free fatty acid receptor 1.

The Journal of biological chemistry 20090626

Metaplasticity of hypothalamic synapses following in vivo challenge.

Neuron 20090625

Spinal mechanisms of antinociceptive action caused by guanosine in mice.

European journal of pharmacology 20090624

Productive versus unproductive nucleotide binding in yeast guanylate kinase mutants: comparison of R41M with K14M by proton two dimensional transferred NOESY.

Biochemistry 20090623

A CA(+) pair adjacent to a sheared GA or AA pair stabilizes size-symmetric RNA internal loops.

Biochemistry 20090623

Conserved glutamate residues Glu-343 and Glu-519 provide mechanistic insights into cation/nucleoside cotransport by human concentrative nucleoside transporter hCNT3.

The Journal of biological chemistry 20090619

Cytokine modulation of TLR expression and activation in mesenchymal stromal cells leads to a proinflammatory phenotype.

Journal of immunology (Baltimore, Md. : 1950) 20090615

The P2Y12 antagonists, 2-methylthioadenosine 5'-monophosphate triethylammonium salt and cangrelor (ARC69931MX), can inhibit human platelet aggregation through a Gi-independent increase in cAMP levels.

The Journal of biological chemistry 20090612

The action of 11-cis-retinol on cone opsins and intact cone photoreceptors.

The Journal of biological chemistry 20090612

Degradation of ppGpp by nudix pyrophosphatase modulates the transition of growth phase in the bacterium Thermus thermophilus.

The Journal of biological chemistry 20090605

Kinetic analysis of the guanine nucleotide exchange activity of TRAPP, a multimeric Ypt1p exchange factor.

Journal of molecular biology 20090605

Small angle X-ray scattering analysis of deoxyguanosine 5'-monophosphate self-assembing in solution: nucleation and growth of G-quadruplexes.

The journal of physical chemistry. B 20090604

Novel crosstalk to BMP signalling: cGMP-dependent kinase I modulates BMP receptor and Smad activity.

The EMBO journal 20090603

Transition state structures and the roles of catalytic residues in GAP-facilitated GTPase of Ras as elucidated by (18)O kinetic isotope effects.

Biochemistry 20090602

Importance of schedule of administration in the therapeutic efficacy of guanosine: early intervention after injury enhances glutamate uptake in model of hypoxia-ischemia.

Journal of molecular neuroscience : MN 20090601

Fetal Hemoglobin Inducers from the Natural World: A Novel Approach for Identification of Drugs for the Treatment of {beta}-Thalassemia and Sickle-Cell Anemia.

Evidence-based complementary and alternative medicine : eCAM 20090601

Kinetic determination of the GTPase activity of Ras proteins by means of a luminescent terbium complex.

Analytical and bioanalytical chemistry 20090601

The Hellenic type of nondeletional hereditary persistence of fetal hemoglobin results from a novel mutation (g.-109G>T) in the HBG2 gene promoter.

Annals of hematology 20090601

Autoantibodies in type 2 diabetes induce stress fiber formation and apoptosis in endothelial cells.

The Journal of clinical endocrinology and metabolism 20090601

Mycophenolic acid inhibits PMA-induced activation of the neutrophil respiratory burst.

Transplant infectious disease : an official journal of the Transplantation Society 20090601

Cyclic GMP signaling in cardiovascular pathophysiology and therapeutics.

Pharmacology & therapeutics 20090601

Characterization of mouse heart adenylyl cyclase.

The Journal of pharmacology and experimental therapeutics 20090601

Adenosine deamination to inosine in isolated basolateral membrane from kidney proximal tubule: implications for modulation of the membrane-associated protein kinase A.

Archives of biochemistry and biophysics 20090601

Bradykinin inhibits the transient outward K+ current in mouse Schwann cells via the cAMP/PKA pathway.

American journal of physiology. Cell physiology 20090601

The cyclic GMP modulators YC-1 and zaprinast reduce vessel remodeling through antiproliferative and proapoptotic effects.

Journal of cardiovascular pharmacology and therapeutics 20090601

G protein independent phosphorylation and internalization of the delta-opioid receptor.

Journal of neurochemistry 20090601

Gating charges per channel of Ca(V)2.2 channels are modified by G protein activation in rat sympathetic neurons.

Archives of biochemistry and biophysics 20090601

Pharmacodynamics of a novel designer natriuretic peptide, CD-NP, in a first-in-human clinical trial in healthy subjects.

Journal of clinical pharmacology 20090601

Borrelia burgdorferi bb0426 encodes a 2'-deoxyribosyltransferase that plays a central role in purine salvage.

Molecular microbiology 20090601

Cloning and characterization of a gene encoding Rac/Rop-like monomeric guanosine 5'-triphosphate-binding protein from Scoparia dulcis.

Biological & pharmaceutical bulletin 20090601

Absolute configurations of spiroiminodihydantoin and allantoin stereoisomers: comparison of computed and measured electronic circular dichroism spectra.

Chemical research in toxicology 20090601

Inhibition of Lassa virus glycoprotein cleavage and multicycle replication by site 1 protease-adapted alpha(1)-antitrypsin variants.

PLoS neglected tropical diseases 20090601

The glyceraldehyde-3-phosphate dehydrogenase and the small GTPase Rab 2 are crucial for Brucella replication.

PLoS pathogens 20090601

Carbachol regulates pacemaker activities in cultured interstitial cells of Cajal from the mouse small intestine.

Molecules and cells 20090531

Crystal structure of the nuclear export receptor CRM1 in complex with Snurportin1 and RanGTP.

Science (New York, N.Y.) 20090522

Apparent non-statistical binding in a ditopic receptor for guanosine.

Organic & biomolecular chemistry 20090521

Chemistry and biology of DNA containing 1,N(2)-deoxyguanosine adducts of the alpha,beta-unsaturated aldehydes acrolein, crotonaldehyde, and 4-hydroxynonenal.

Chemical research in toxicology 20090518

Electrochemical behaviors of guanosine on carbon ionic liquid electrode and its determination.

Talanta 20090515

Rapid changes in shear stress induce dissociation of a G alpha(q/11)-platelet endothelial cell adhesion molecule-1 complex.

The Journal of physiology 20090515

The deazapurine biosynthetic pathway revealed: in vitro enzymatic synthesis of PreQ(0) from guanosine 5'-triphosphate in four steps.

Biochemistry 20090512

Epitope-tagged receptor knock-in mice reveal that differential desensitization of alpha2-adrenergic responses is because of ligand-selective internalization.

The Journal of biological chemistry 20090508

Influence of water hydrogen bonding on the reactions of arylnitrenium ions with guanosine: hydrogen-bonding effects can favor reaction at the C8 site.

The journal of physical chemistry. B 20090507

Bacterial alarmone, guanosine 5'-diphosphate 3'-diphosphate (ppGpp), predominantly binds the beta' subunit of plastid-encoded plastid RNA polymerase in chloroplasts.

Chembiochem : a European journal of chemical biology 20090504

The N-terminal domain of GPR61, an orphan G-protein-coupled receptor, is essential for its constitutive activity.

Journal of neuroscience research 20090501

The in vitro and in ovo responses of chickens to TLR9 subfamily ligands.

Developmental and comparative immunology 20090501

Calpain-mediated degradation of G-substrate plays a critical role in retinal excitotoxicity for amacrine cells.

Journal of neuroscience research 20090501

Effect of sildenafil on acrolein-induced airway inflammation and mucus production in rats.

The European respiratory journal 20090501

Phenolic acids suppress adipocyte lipolysis via activation of the nicotinic acid receptor GPR109A (HM74a/PUMA-G).

Journal of lipid research 20090501

Separation and identification of purine nucleosides in the urine of patients with malignant cancer by reverse phase liquid chromatography/electrospray tandem mass spectrometry.

Journal of mass spectrometry : JMS 20090501

Interstitial cells of Cajal contain signalling molecules for transduction of nitrergic stimulation in guinea pig caecum.

Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society 20090501

Plant and fungal Fpg homologs are formamidopyrimidine DNA glycosylases but not 8-oxoguanine DNA glycosylases.

DNA repair 20090501

A class C CpG toll-like receptor 9 agonist successfully induces robust interferon-alpha production by plasmacytoid dendritic cells from patients chronically infected with hepatitis C.

Journal of viral hepatitis 20090501

A functional link between T-type calcium channels and mu-opioid receptor expression in adult primary sensory neurons.

Journal of neurochemistry 20090501

Functional role of J domain of cysteine string protein in Ca2+-dependent secretion from acinar cells.

American journal of physiology. Gastrointestinal and liver physiology 20090501

Activators of G proteins inhibit GSK-3beta and stabilize beta-Catenin in Xenopus oocytes.

Biochemical and biophysical research communications 20090501

Neurofibromatosis type 1 and associated malignancies.

Current neurology and neuroscience reports 20090501

Ser/Thr/Tyr phosphoproteome analysis of pathogenic and non-pathogenic Pseudomonas species.

Proteomics 20090501

The SARS-unique domain (SUD) of SARS coronavirus contains two macrodomains that bind G-quadruplexes.

PLoS pathogens 20090501

Modulation of RNA metal binding by flanking bases: 15N NMR evaluation of GC, tandem GU, and tandem GA sites.

Nucleosides, nucleotides & nucleic acids 20090501

G-quadruplex self-assembly regulated by Coulombic interactions.

Nature chemistry 20090501

The presence of circulating total DNA and methylated genes is associated with circulating tumour cells in blood from breast cancer patients.

British journal of cancer 20090421

IR-UV double resonance spectroscopy of the hydrated clusters of guanosine and 9-methylguanine: evidence for hydration structures involving the sugar group.

The journal of physical chemistry. A 20090416

A novel method for the detection of point mutation in DNA using single-base-coded CdS nanoprobes.

Biosensors & bioelectronics 20090415

[35S]GTP gamma S binding studies of amphiphilic drugs-activated Gi proteins: a caveat.

Bioorganic & medicinal chemistry letters 20090415

The significance of EXDD and RXKD motif conservation in Rel proteins.

The Journal of biological chemistry 20090403

Stabilizing guanosine-sterol ion channels with a carbamate to urea modification in the linker.

Organic letters 20090402

Mycophenolic acid inhibits oleic acid-induced mesangial cell activation through both cellular reactive oxygen species and inosine monophosphate dehydrogenase 2 pathways.

Pediatric nephrology (Berlin, Germany) 20090401

Extracellular guanosine and GTP promote expression of differentiation markers and induce S-phase cell-cycle arrest in human SH-SY5Y neuroblastoma cells.

International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience 20090401

Cholinergic direct inhibition of N-methyl-D aspartate receptor-mediated currents in the rat neocortex.

Synapse (New York, N.Y.) 20090401

JNJ-20788560 [9-(8-azabicyclo[3.2.1]oct-3-ylidene)-9H-xanthene-3-carboxylic acid diethylamide], a selective delta opioid receptor agonist, is a potent and efficacious antihyperalgesic agent that does not produce respiratory depression, pharmacologic tolerance, or physical dependence.

The Journal of pharmacology and experimental therapeutics 20090401

Toll-like receptor 7 cooperates with IL-4 in activated B cells through antigen receptor or CD38 and induces class switch recombination and IgG1 production.

Molecular immunology 20090401

Facilitated mitochondrial import of antiviral and anticancer nucleoside drugs by human equilibrative nucleoside transporter-3.

American journal of physiology. Gastrointestinal and liver physiology 20090401

Evaluation of urinary nucleosides in breast cancer patients before and after tumor removal.

Clinical biochemistry 20090401

Suppression of prostaglandin E2-induced MUC5AC overproduction by RGS4 in the airway.

American journal of physiology. Lung cellular and molecular physiology 20090401

Exogenous adenosine reduces the mitochondrial membrane potential of murine oocytes during the latter half of in vitro maturation and pronuclear formation following chemical activation.

The Journal of reproduction and development 20090401

Cerebral haemodynamic response or excitability is not affected by sildenafil.

Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 20090401

Characterization of a mimivirus RNA cap guanine-N2 methyltransferase.

RNA (New York, N.Y.) 20090401

Differential effects of calcium-channel blockers on vascular endothelial function in patients with coronary spastic angina.

Circulation journal : official journal of the Japanese Circulation Society 20090401

Agonist activity of N-desmethylclozapine at delta-opioid receptors of human frontal cortex.

European journal of pharmacology 20090401

The purine nucleosides adenosine and guanosine delay axonal degeneration in vitro.

Journal of neurochemistry 20090401

The Borrelia burgdorferi flaB promoter has an extended -10 element and includes a T-rich -35/-10 spacer sequence that is essential for optimal activity.

FEMS microbiology letters 20090401

Stringent response in Vibrio cholerae: genetic analysis of spoT gene function and identification of a novel (p)ppGpp synthetase gene.

Molecular microbiology 20090401

Structure analysis of the conserved methyltransferase domain of human trimethylguanosine synthase TGS1.

Acta crystallographica. Section D, Biological crystallography 20090401

Isolation of plasma membrane compartments from rat brain cortex; detection of agonist-stimulated G protein activity.

Medical science monitor : international medical journal of experimental and clinical research 20090401

A study of the pH dependence of electronically excited guanosine compounds by picosecond time-resolved infrared spectroscopy.

Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology 20090401

Endocannabinoid-mediated long-term depression in the avian midbrain expressed presynaptically and postsynaptically.

The Journal of neuroscience : the official journal of the Society for Neuroscience 20090401

Receptor-independent modulation of reconstituted Galpha(i) protein mediated by liposomes.

Molecular bioSystems 20090401

Vessel dilator and kaliuretic peptide inhibit Ras in human prostate cancer cells.

Anticancer research 20090401

[Molecular regulation of microbial secondary metabolites--a review].

Wei sheng wu xue bao = Acta microbiologica Sinica 20090401

Site-specific regulation of CA(V)2.2 channels by protein kinase C isozymes betaII and epsilon.

Neuroscience 20090317

Quantitative analysis of RNA solvent accessibility by N-silylation of guanosine.

Biochemistry 20090317

Mechanistic aspects of the formation of guanidinohydantoin from spiroiminodihydantoin under acidic conditions.

Chemical research in toxicology 20090316

Characterization of oxidized guanosine 5'-triphosphate as a viable inhibitor of soluble guanylyl cyclase.

Free radical biology & medicine 20090315

Qualitative evaluation and quantitative determination of 10 major active components in Carthamus tinctorius L. by high-performance liquid chromatography coupled with diode array detector.

Journal of chromatography. A 20090313

APOBEC proteins and intrinsic resistance to HIV-1 infection.

Philosophical transactions of the Royal Society of London. Series B, Biological sciences 20090312

Helical structure of disodium 5'-guanosine monophosphate self-assembly in neutral solution.

Journal of the American Chemical Society 20090311

Solvent-induced high fidelity switching between two discrete supramolecules.

Journal of the American Chemical Society 20090311

Synthesis of 2'-C-beta-methyl-2'-deoxyguanosine.

The Journal of organic chemistry 20090306

Specific regulation of mRNA cap methylation by the c-Myc and E2F1 transcription factors.

Oncogene 20090305

Responses to 5-HT in morphologically identified neurons in the rat substantia gelatinosa in vitro.

Neuroscience 20090303

Development of selective agonists and antagonists of P2Y receptors.

Purinergic signalling 20090301

Allosteric modulation of adenosine receptors.

Purinergic signalling 20090301

S100B overexpressing mutant mice exhibit prolonged behavioural and biochemical responses towards repeated intermittent binge treatments with MDMA.

The international journal of neuropsychopharmacology 20090301

Ceramide 1-phosphate (C1P) promotes cell migration Involvement of a specific C1P receptor.

Cellular signalling 20090301

Glutamate receptor mGlu2 and mGlu3 knockout striata are dopamine supersensitive, with elevated D2(High) receptors and marked supersensitivity to the dopamine agonist (+)PHNO.

Synapse (New York, N.Y.) 20090301

Pharmacological assessments of nitric oxide synthase isoforms and downstream diversity of NO signaling in the maintenance of thermal and mechanical hypersensitivity after peripheral nerve injury in mice.

Neuropharmacology 20090301

Biochemical characterization and homology modeling of a purine-specific ribonucleoside hydrolase from the archaeon Sulfolobus solfataricus: insights into mechanisms of protein stabilization.

Archives of biochemistry and biophysics 20090301

GTPgammaS antagonizes the mastoparan-induced in vitro activity of PIP-phospholipase C from symbiotic root nodules of Phaseolus vulgaris.

Physiologia plantarum 20090301

Allosteric modulation of metabotropic glutamate receptor 5 affects phosphorylation, internalization, and desensitization of the micro-opioid receptor.

Neuropharmacology 20090301

Guanosine and synthetic organoselenium compounds modulate methylmercury-induced oxidative stress in rat brain cortical slices: involvement of oxidative stress and glutamatergic system.

Toxicology in vitro : an international journal published in association with BIBRA 20090301

Side-on binding of p-sulphonatocalix[4]arene to the dinuclear platinum complex trans-[{PtCl(NH3)2}2mu-dpzm]2+ and its implications for anticancer drug delivery.

Journal of inorganic biochemistry 20090301

Modulation of the cGMP signaling pathway by melatonin in pancreatic beta-cells.

Journal of pineal research 20090301

U18666A, a cholesterol-inhibition agent, modulates human neuronal nicotinic acetylcholine receptors heterologously expressed in SH-EP1 cell line.

Journal of neurochemistry 20090301

Altered CB receptor-signaling in prefrontal cortex from an animal model of depression is reversed by chronic fluoxetine.

Journal of neurochemistry 20090301

Role of natriuretic peptides in cGMP production in fetal cardiac bypass.

The Annals of thoracic surgery 20090301

Expression of ABCC-type nucleotide exporters in blasts of adult acute myeloid leukemia: relation to long-term survival.

Clinical cancer research : an official journal of the American Association for Cancer Research 20090301

Escherichia coli MazF leads to the simultaneous selective synthesis of both 'death proteins' and 'survival proteins'.

PLoS genetics 20090301

Bacterial toxin-antitoxin systems: more than selfish entities?

PLoS genetics 20090301

Mycophenolic Acid Inhibits p38 Mitogen-Activated Protein Kinase in Human Monocyte-Derived Dendritic Cells Stimulated by Lipopolysaccharide.

Transplantation proceedings 20090301

Hepatitis B in HIV patients: what is the current treatment and what are the challenges?

Journal of HIV therapy 20090301

Functional characteristics of TRPC4 channels expressed in HEK 293 cells.

Molecules and cells 20090227

Morphine increases brain levels of ferritin heavy chain leading to inhibition of CXCR4-mediated survival signaling in neurons.

The Journal of neuroscience : the official journal of the Society for Neuroscience 20090225

Reaction of hydrated electrons with guanine derivatives: tautomerism of intermediate species.

The journal of physical chemistry. B 20090219

High constitutive activity and a G-protein-independent high-affinity state of the human histamine H(4)-receptor.

Biochemistry 20090217

Guanosine improves motor behavior, reduces apoptosis, and stimulates neurogenesis in rats with parkinsonism.

Journal of neuroscience research 20090215

Development and validation of an LC-MS/MS method for quantification of cyclic guanosine 3',5'-monophosphate (cGMP) in clinical applications: a comparison with a EIA method.

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20090215

Guanidine and 2-aminoimidazoline aromatic derivatives as alpha2-adrenoceptor ligands: searching for structure-activity relationships.

Journal of medicinal chemistry 20090212

Analysis of flavivirus NS5 methyltransferase cap binding.

Journal of molecular biology 20090206

Oxidation and glycolytic cleavage of etheno and propano DNA base adducts.

Biochemistry 20090203

Determinants of the voltage dependence of G protein modulation within calcium channel beta subunits.

Pflugers Archiv : European journal of physiology 20090201

Interaction of retinal guanylate cyclase with the alpha subunit of transducin: potential role in transducin localization.

The Biochemical journal 20090201

The NMDA antagonist MK-801 induces hyperalgesia and increases CSF excitatory amino acids in rats: reversal by guanosine.

Pharmacology, biochemistry, and behavior 20090201

Biochemical characterization of rab proteins from Bombyx mori.

Archives of insect biochemistry and physiology 20090201

Allosteric modulation of 5-HT(1A) receptors by zinc: Binding studies.

Neuropharmacology 20090201

Chronic high-NaCl intake prolongs the cardiorenal responses to central N/OFQ and produces regional changes in the endogenous brain NOP receptor system.

American journal of physiology. Regulatory, integrative and comparative physiology 20090201

Sphingosine-1-phosphate induced mTOR-activation is mediated by the E3-ubiquitin ligase PAM.

Cellular signalling 20090201

Acute and chronic effects of citalopram on 5-HT1A receptor-labeling by [18F]MPPF and -coupling to receptors-G proteins.

Synapse (New York, N.Y.) 20090201

SpoT governs Legionella pneumophila differentiation in host macrophages.

Molecular microbiology 20090201

The RhoGDI-alpha/JNK signaling pathway plays a significant role in mycophenolic acid-induced apoptosis in an insulin-secreting cell line.

Cellular signalling 20090201

Regulation of IL2 and NUCB1 in mononuclear cells treated with acyl glucuronide of mycophenolic acid reveals effects independent of inosine monophosphate dehydrogenase inhibition.

Therapeutic drug monitoring 20090201

A natural ribozyme with 3',5' RNA ligase activity.

Nature chemical biology 20090201

The ontogenetic expression pattern of type 5 phosphodiesterase correlates with androgen receptor expression in rat corpora cavernosa.

The journal of sexual medicine 20090201

High-throughput screening for small-molecule inhibitors of LARG-stimulated RhoA nucleotide binding via a novel fluorescence polarization assay.

Journal of biomolecular screening 20090201

Protection of mice against X-ray injuries by the post-irradiation administration of guanosine and inosine.

International journal of radiation biology 20090201

The psychostimulant d-threo-(R,R)-methylphenidate binds as an agonist to the 5HT(1A) receptor.

Die Pharmazie 20090201

Binding studies of novel, non-mammalian enkephalins, structures predicted from frog and lungfish brain cDNA sequences.

Neuroscience 20090123

Increased oxidative stress in patients with amyotrophic lateral sclerosis/Parkinsonism-dementia complex in the Kii peninsula, Japan.

Movement disorders : official journal of the Movement Disorder Society 20090115

Redefining the structure-activity relationships of 2,6-methano-3-benzazocines. Part 7: syntheses and opioid receptor properties of cyclic variants of cyclazocine.

Bioorganic & medicinal chemistry letters 20090115

Electronic structure of DNA--unique properties of 8-oxoguanosine.

Journal of the American Chemical Society 20090114

Glucocorticoids regulate glutamate and GABA synapse-specific retrograde transmission via divergent nongenomic signaling pathways.

The Journal of neuroscience : the official journal of the Society for Neuroscience 20090114

Regulation of long-term depression by increases in [guanosine 3',5'-cyclic monophosphate] in the hippocampal CA1 region of freely behaving rats.

Neuroscience 20090112

Stimulation of mammalian G-protein-responsive adenylyl cyclases by carbon dioxide.

The Journal of biological chemistry 20090109

The C-terminal tail of CRTH2 is a key molecular determinant that constrains Galphai and downstream signaling cascade activation.

The Journal of biological chemistry 20090109

Cloning and pharmacological characterization of a novel gene encoding human nucleoside transporter 1 (hNT1) from a human breast cancer cDNA library.

Life sciences 20090102

Investigating oxidative DNA damage and its repair using the comet assay.

Mutation research 20090101

Activation of G proteins and extracellular signal-regulated kinase 1/2 phosphorylation via human dopamine D4.4 receptors: differential pathway-dependent potencies of receptor agonists.

Naunyn-Schmiedeberg's archives of pharmacology 20090101

Selective phosphodiesterase inhibitors: a promising target for cognition enhancement.

Psychopharmacology 20090101

Mycophenolic acid inhibits the autocrine PDGF-B synthesis and PDGF-BB-induced mRNA expression of Egr-1 in rat mesangial cells.

Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20090101

Progestin signaling through an olfactory G protein and membrane progestin receptor-alpha in Atlantic croaker sperm: potential role in induction of sperm hypermotility.

Endocrinology 20090101

Mitochondrial DNA damage is a hallmark of chemically induced and the R6/2 transgenic model of Huntington's disease.

DNA repair 20090101

The Gq and G12 families of heterotrimeric G proteins report functional selectivity.

Molecular pharmacology 20090101

Role of Src in ligand-specific regulation of delta-opioid receptor desensitization and internalization.

Journal of neurochemistry 20090101

cGMP in the vasculature.

Handbook of experimental pharmacology 20090101

cGMP signalling in the mammalian brain: role in synaptic plasticity and behaviour.

Handbook of experimental pharmacology 20090101

Acetylation of the amino group on guanosine induced by nitric oxide in acetonitrile under aerobic conditions.

Chemical & pharmaceutical bulletin 20090101

Iron behaving badly: inappropriate iron chelation as a major contributor to the aetiology of vascular and other progressive inflammatory and degenerative diseases.

BMC medical genomics 20090101

Anti-nociceptive properties of the xanthine oxidase inhibitor allopurinol in mice: role of A1 adenosine receptors.

British journal of pharmacology 20090101

Humanized ADEPT comprised of an engineered human purine nucleoside phosphorylase and a tumor targeting peptide for treatment of cancer.

Molecular cancer therapeutics 20090101

TraR, a homolog of a RNAP secondary channel interactor, modulates transcription.

PLoS genetics 20090101

Novel exon of mammalian ADAR2 extends open reading frame.

PloS one 20090101

Transcriptomic comparison of Aspergillus niger growing on two different sugars reveals coordinated regulation of the secretory pathway.

BMC genomics 20090101

Evidence for niche adaptation in the genome of the bovine pathogen Streptococcus uberis.

BMC genomics 20090101

Therapeutic antioxidant medical gas.

Journal of clinical biochemistry and nutrition 20090101

8-Oxo-7,8-dihydro-2'-deoxyguanosine Forms a Relatively Unstable Tetrameric Structure Compared with 2'-Deoxyguanosine.

Journal of clinical biochemistry and nutrition 20090101

Escherichia coli genes affecting recipient ability in plasmid conjugation: are there any?

BMC genomics 20090101

Comparison between the HCV IRES domain IV RNA structure and the Iron Responsive Element.

Journal of negative results in biomedicine 20090101

A reevaluation of the ambident reactivity of the guanine moiety towards hydroxyl radicals.

Angewandte Chemie (International ed. in English) 20090101

Outline of a genome navigation system based on the properties of GA-sequences and their flanks.

PloS one 20090101

Reconstruction of metabolic pathways for the cattle genome.

BMC systems biology 20090101

Receptor-induced dilatation in the systemic and intrarenal adaptation to pregnancy in rats.

PloS one 20090101

cGMP-dependent protein kinase I is crucial for angiogenesis and postnatal vasculogenesis.

PloS one 20090101

Segment-dependent activation of muscarinic acetylcholine receptor-mediated [35S]Guanosine-5'-O-(gamma-thiotriphosphate) binding in airway tissue membranes.

Pharmacology 20090101

[Effect of estradiol on Ca2+ release from intracellular stores in porcine oocytes stimulated by prolactin, theophylline, or guanosine triphosphate].

Ontogenez 20090101

Prediction of breast cancer by profiling of urinary RNA metabolites using Support Vector Machine-based feature selection.

BMC cancer 20090101

Constraint-based analysis of metabolic capacity of Salmonella typhimurium during host-pathogen interaction.

BMC systems biology 20090101

Inhibition of Rac and Rac-linked functions by 8-oxo-2'-deoxyguanosine in murine macrophages.

Free radical research 20090101

Bioinformatics analysis suggests base modifications of tRNAs and miRNAs in Arabidopsis thaliana.

BMC genomics 20090101

Analysis of the Rickettsia africae genome reveals that virulence acquisition in Rickettsia species may be explained by genome reduction.

BMC genomics 20090101

Proteome serological determination of tumor-associated antigens in melanoma.

PloS one 20090101

The effect of high glucocorticoid administration and food restriction on rodent skeletal muscle mitochondrial function and protein metabolism.

PloS one 20090101

Hydroxyl radical oxidation of guanosine 5'-triphosphate (GTP): requirement for a GTP-Cu(II) complex.

Redox report : communications in free radical research 20090101

Short hairpin-loop-structured oligodeoxynucleotides reduce HSV-1 replication.

Virology journal 20090101

Molecular profiles of Quadriceps muscle in myostatin-null mice reveal PI3K and apoptotic pathways as myostatin targets.

BMC genomics 20090101

Comparative component analysis of exons with different splicing frequencies.

PloS one 20090101

Overexpression of nuclear transport factor 2 may protect against diabetic retinopathy.

Molecular vision 20090101

Mycophenolate mofetil: safety and efficacy in the prophylaxis of acute kidney transplantation rejection.

Therapeutics and clinical risk management 20090101

Comprehensive comparative-genomic analysis of type 2 toxin-antitoxin systems and related mobile stress response systems in prokaryotes.

Biology direct 20090101

[35S]GTPgammaS binding in G protein-coupled receptor assays.

Methods in molecular biology (Clifton, N.J.) 20090101

The encapsulation and release of guanosine from PEGylated liposomes.

Journal of liposome research 20090101

Cigarette smoke attenuates the production of cytokines by human plasmacytoid dendritic cells and enhances the release of IL-8 in response to TLR-9 stimulation.

Respiratory research 20090101

Bench-to-bedside review: Inhaled nitric oxide therapy in adults.

Critical care (London, England) 20090101

The immune system and the impact of zinc during aging.

Immunity & ageing : I & A 20090101

Hypoglycemic herbs and their action mechanisms.

Chinese medicine 20090101

[The preparative method for 2-fluoroadenosine synthesis].

Bioorganicheskaia khimiia 20090101

Simultaneous live cell imaging using dual FRET sensors with a single excitation light.

PloS one 20090101

G-rich oligonucleotides for cancer treatment.

Methods in molecular biology (Clifton, N.J.) 20090101

Intracellular localization and conformational state of transglutaminase 2: implications for cell death.

PloS one 20090101

Conservation of structure and activity in Plasmodium purine nucleoside phosphorylases.

BMC structural biology 20090101

Purine nucleoside phosphorylase deficiency in two unrelated Saudi patients.

Annals of Saudi medicine 20090101

Rab4b is a small GTPase involved in the control of the glucose transporter GLUT4 localization in adipocyte.

PloS one 20090101

Illuminating the life of GPCRs.

Cell communication and signaling : CCS 20090101

Estrous cycle influences the expression of neuronal nitric oxide synthase in the hypothalamus and limbic system of female mice.

BMC neuroscience 20090101

Guanine nucleotides in the meiotic maturation of starfish oocytes: regulation of the actin cytoskeleton and of Ca(2+) signaling.

PloS one 20090101

Drosophila photoreceptors and signaling mechanisms.

Frontiers in cellular neuroscience 20090101

DNA binding by Corynebacterium glutamicum TetR-type transcription regulator AmtR.

BMC molecular biology 20090101

A Dictyostelium chalone uses G proteins to regulate proliferation.

BMC biology 20090101

Hidden chromosome symmetry: in silico transformation reveals symmetry in 2D DNA walk trajectories of 671 chromosomes.

PloS one 20090101

Human guanylate binding proteins potentiate the anti-chlamydia effects of interferon-gamma.

PloS one 20090101

Pinellia ternata, Citrus reticulata, and their combinational prescription inhibit eosinophil infiltration and airway hyperresponsiveness by suppressing CCR3+ and Th2 cytokines production in the ovalbumin-induced asthma model.

Mediators of inflammation 20090101

Positive selection at codon 38 of the human KCNE1 (= minK) gene and sporadic absence of 38Ser-coding mRNAs in Gly38Ser heterozygotes.

BMC evolutionary biology 20090101

Genome-wide profile of pleural mesothelioma versus parietal and visceral pleura: the emerging gene portrait of the mesothelioma phenotype.

PloS one 20090101

Regulation of MicroRNA Biogenesis: A miRiad of mechanisms.

Cell communication and signaling : CCS 20090101

Lipid raft-mediated regulation of G-protein coupled receptor signaling by ligands which influence receptor dimerization: a computational study.

PloS one 20090101

Equilibrium and kinetic investigations of the interaction of model platinum(II) complex with DNA constituents in reference to the antitumour activity: complex-formation reactions of [Pd(N,N-diethylethylenediamine)(H2O)2]2+ with ligands of biological significance and displacement reactions of DNA constituents.

Bioinorganic chemistry and applications 20090101

The role of relA and spoT in Yersinia pestis KIM5 pathogenicity.

PloS one 20090101

On the origin of life in the zinc world: 1. Photosynthesizing, porous edifices built of hydrothermally precipitated zinc sulfide as cradles of life on Earth.

Biology direct 20090101

Pharmacotherapy of pediatric and adolescent HIV infection.

Therapeutics and clinical risk management 20090101

A differential effect of E. coli toxin-antitoxin systems on cell death in liquid media and biofilm formation.

PloS one 20090101

Differential bacterial surface display of peptides by the transmembrane domain of OmpA.

PloS one 20090101

Structure and function converge to identify a hydrogen bond in a group I ribozyme active site.

Angewandte Chemie (International ed. in English) 20090101

Preparation of group I introns for biochemical studies and crystallization assays by native affinity purification.

PloS one 20090101

Glucose absorption and gastric emptying in critical illness.

Critical care (London, England) 20090101

Genotoxicity of nano/microparticles in in vitro micronuclei, in vivo comet and mutation assay systems.

Particle and fibre toxicology 20090101

9-(2-C-Cyano-2-deoxy-beta-D-arabino-pentofuranosyl)guanine, a potential antitumor agent against B-lymphoma infected with Kaposi's sarcoma-associated herpesvirus.

Nucleic acids symposium series (2004) 20090101

Analysis of an RNA adduct formed from aminophenylnorharman.

Nucleic acids symposium series (2004) 20090101

The oxidation of 2'-deoxy-8-oxoguanosine by iodine.

Nucleic acids symposium series (2004) 20090101

Identification of gemin5 as a novel 7-methylguanosine cap-binding protein.

PloS one 20090101

Mycophenolic acid formulations in adult renal transplantation - update on efficacy and tolerability.

Therapeutics and clinical risk management 20090101

Gender-specific modulation of the response to arterial injury by soluble guanylate cyclase α1.

The open cardiovascular medicine journal 20090101

FGF4 independent derivation of trophoblast stem cells from the common vole.

PloS one 20090101

Glutamate uptake triggers transporter-mediated GABA release from astrocytes.

PloS one 20090101

ERG-associated protein with SET domain (ESET)-Oct4 interaction regulates pluripotency and represses the trophectoderm lineage.

Epigenetics & chromatin 20090101

Molecular models for intrastrand DNA G-quadruplexes.

BMC structural biology 20090101

A man-made ATP-binding protein evolved independent of nature causes abnormal growth in bacterial cells.

PloS one 20090101

Initial implementation of a comparative data analysis ontology.

Evolutionary bioinformatics online 20090101

Impaired glucose and nutrient absorption in critical illness: is gastric emptying only a piece of the puzzle?

Critical care (London, England) 20090101

L-type channel inhibition by CB1 cannabinoid receptors is mediated by PTX-sensitive G proteins and cAMP/PKA in GT1-7 hypothalamic neurons.

Cell calcium 20090101

Gene expression analysis of the biocontrol fungus Trichoderma harzianum in the presence of tomato plants, chitin, or glucose using a high-density oligonucleotide microarray.

BMC microbiology 20090101

Post-transcriptional control of chloroplast gene expression.

Gene regulation and systems biology 20090101

Graves' disease associated with primary systemic sclerosis.

Orbit (Amsterdam, Netherlands) 20090101

Functional characterization of N-terminally GFP-tagged GLP-1 receptor.

Journal of biomedicine & biotechnology 20090101

The role and molecular mechanism of D-aspartic acid in the release and synthesis of LH and testosterone in humans and rats.

Reproductive biology and endocrinology : RB&E 20090101

'cAMP sponge': a buffer for cyclic adenosine 3', 5'-monophosphate.

PloS one 20090101

Long-term prediction of fish growth under varying ambient temperature using a multiscale dynamic model.

BMC systems biology 20090101

The charge-transfer band of an oxidized watson-crick guanosine-cytidine complex.

Angewandte Chemie (International ed. in English) 20090101

Predominant membrane localization is an essential feature of the bacterial signal recognition particle receptor.

BMC biology 20090101

Activation of adenosine A2B receptors enhances ciliary beat frequency in mouse lateral ventricle ependymal cells.

Cerebrospinal fluid research 20090101

Quantifying and resolving multiple vector transformants in S. cerevisiae plasmid libraries.

BMC biotechnology 20090101

Tackling the methylome: recent methodological advances in genome-wide methylation profiling.

Genome medicine 20090101

Glycine Receptors Caught between Genome and Proteome - Functional Implications of RNA Editing and Splicing.

Frontiers in molecular neuroscience 20090101

Homocysteine may contribute to pathogenesis of RNA damage in brains with Alzheimer's disease.

Neuro-degenerative diseases 20090101

Evidence for ADAR-induced hypermutation of the Drosophila sigma virus (Rhabdoviridae).

BMC genetics 20090101

Identification and expression analysis of ras gene in silkworm, Bombyx mori.

PloS one 20090101

Characterization of an engineered human purine nucleoside phosphorylase fused to an anti-her2/neu single chain Fv for use in ADEPT.

Journal of experimental & clinical cancer research : CR 20090101

NADPH oxidase expression and production of superoxide by human corneal stromal cells.

Molecular vision 20090101

Nuclear factor I-A represses expression of the cell adhesion molecule L1.

BMC molecular biology 20090101

Human synthetic lethal inference as potential anti-cancer target gene detection.

BMC systems biology 20090101

Proteome-based analysis of serologically defined tumor-associated antigens in cutaneous lymphoma.

PloS one 20090101

The repertoire of equine intestinal alpha-defensins.

BMC genomics 20090101

Understanding the molecular basis of plant growth promotional effect of Pseudomonas fluorescens on rice through protein profiling.

Proteome science 20090101

Divergence of allosteric effects of rapacuronium on binding and function of muscarinic receptors.

BMC pharmacology 20090101

Genetic variations in the HGPRT, ITPA, IMPDH1, IMPDH2, and GMPS genes in Japanese individuals.

Drug metabolism and pharmacokinetics 20090101

P19 H-ras induces G1/S phase delay maintaining cells in a reversible quiescence state.

PloS one 20090101

Mizoribine: a new approach in the treatment of renal disease.

Clinical & developmental immunology 20090101

Brain natriuretic peptide in pulmonary arterial hypertension: biomarker and potential therapeutic agent.

Drug design, development and therapy 20090101

A new photosensory function for simple photoreceptors, the intrinsically photoresponsive neurons of the sea slug onchidium.

Frontiers in cellular neuroscience 20090101

Control of oocyte release by progesterone receptor-regulated gene expression.

Nuclear receptor signaling 20090101

A comprehensive review of immunosuppression used for liver transplantation.

Journal of transplantation 20090101

The treatment of chronic hepatitis C virus infection in HIV co-infection.

European journal of medical research 20090101

Quality, stability, and safety data of packed red cells and plasma processed by gravity separation using a new fully integrated hollow-fibre filter device.

Advances in hematology 20090101

Vasopressin in the pediatric cardiac intensive care unit: Myth or reality.

Annals of pediatric cardiology 20090101

Immunoregulation through IL-10 gene expression and the fate of cytotoxic T lymphocyte-mediated tumor immunotherapy.

Indian journal of human genetics 20090101

Setting the absolute threshold of vision.

F1000 biology reports 20090101

Oxidative stress as a mediator of cardiovascular disease.

Oxidative medicine and cellular longevity 20090101

Bitopic ligands: all-in-one orthosteric and allosteric.

F1000 biology reports 20090101

Endocannabinoid receptor pharmacology.

Current topics in behavioral neurosciences 20090101

Tacrolimus ointment in the management of atopic dermatitis.

Clinical, cosmetic and investigational dermatology 20090101

Protective effects of solvent fractions of Mentha spicata (L.) leaves evaluated on 4-nitroquinoline-1-oxide induced chromosome damage and apoptosis in mouse bone marrow cells.

Genetics and molecular biology 20090101

Assessment of the Potential Role of Tryptophan as the Precursor of Serotonin and Melatonin for the Aged Sleep-wake Cycle and Immune Function: Streptopelia Risoria as a Model.

International journal of tryptophan research : IJTR 20090101

Distinct pattern of mutations of conserved regions of TP53 in colorectal cancer patients in the Kashmir population: an emerging high-risk area.

Ecancermedicalscience 20090101

Calculation of pKa values of nucleobases and the guanine oxidation products guanidinohydantoin and spiroiminodihydantoin using density functional theory and a polarizable continuum model.

The journal of physical chemistry. B 20081225

Probes for narcotic receptor mediated phenomena. 37. Synthesis and opioid binding affinity of the final pair of oxide-bridged phenylmorphans, the ortho- and para-b-isomers and their N-phenethyl analogues, and the synthesis of the N-phenethyl analogues of the ortho- and para-d-isomers.

Journal of medicinal chemistry 20081225

Effect of hyperoxidized guanine on DNA primer-template structures: spiroiminodihydantoin leads to strand slippage.

FEBS letters 20081224

GAP1(IP4BP)/RASA3 mediates Galphai-induced inhibition of mitogen-activated protein kinase.

The Journal of biological chemistry 20081219

In vitro synthesis and characterization of guanosine 3',5'-bis(diphosphate).

Analytical biochemistry 20081215

Synthesis of a novel 6,14-epoxymorphinan derivative and its pharmacology.

Bioorganic & medicinal chemistry letters 20081215

Simultaneous determination of nucleobases, nucleosides and saponins in Panax notoginseng using multiple columns high performance liquid chromatography.

Journal of pharmaceutical and biomedical analysis 20081215

The specific activation of TRPC4 by Gi protein subtype.

Biochemical and biophysical research communications 20081212

8-Nitroguanosines as chemical probes of the protein S-guanylation.

Chemical communications (Cambridge, England) 20081207

Differential coupling of the human cannabinoid receptors hCB1R and hCB2R to the G-protein G(alpha)i2beta1gamma2.

Neuroscience letters 20081205

Muscarinic receptor changes in the gerbil thalamus during aging.

Brain research 20081203

Functional coupling of mu-receptor-Galphai-tethered proteins in AtT20 cells.

Neuroreport 20081203

Enhancement of mucosal immune responses by intranasal co-delivery of Newcastle disease vaccine plus CpG oligonucleotide in SPF chickens in vivo.

Research in veterinary science 20081201

Angiotensin II type 1 receptor blocker ameliorates uncoupled endothelial nitric oxide synthase in rats with experimental diabetic nephropathy.

Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20081201

Antioxidative effects of statins.

Archives of toxicology 20081201

Antipsychotic-induced alterations in CB1 receptor-mediated G-protein signaling and in vivo pharmacology in rats.

Neuropharmacology 20081201

Nuclear factor-kappaB mediates the inhibitory effects of tumor necrosis factor-alpha on growth hormone-inducible gene expression in liver.

Endocrinology 20081201

Identification and characterization of NDT 9513727 [N,N-bis(1,3-benzodioxol-5-ylmethyl)-1-butyl-2,4-diphenyl-1H-imidazole-5-methanamine], a novel, orally bioavailable C5a receptor inverse agonist.

The Journal of pharmacology and experimental therapeutics 20081201

A novel delta opioid receptor antagonist, SoRI-9409, produces a selective and long-lasting decrease in ethanol consumption in heavy-drinking rats.

Biological psychiatry 20081201

Mechanisms of EHD/RME-1 protein function in endocytic transport.

Traffic (Copenhagen, Denmark) 20081201

Binding of the novel radioligand [(3)H]UFP-101 to recombinant human and native rat nociceptin/orphanin FQ receptors.

Naunyn-Schmiedeberg's archives of pharmacology 20081201

WAY100635 prevents the changes induced by fluoxetine upon the 5-HT1A receptor functionality.

Neuropharmacology 20081201

Inhibitory effects of epoxyeicosatrienoic acids on volume-activated chloride channels in rat mesenteric arterial smooth muscle.

Prostaglandins & other lipid mediators 20081201

Identification and functional characterization of allosteric agonists for the G protein-coupled receptor FFA2.

Molecular pharmacology 20081201

ARAP1 regulates endocytosis of EGFR.

Traffic (Copenhagen, Denmark) 20081201

Rel/NF-kappaB family member RelA regulates NK1.1- to NK1.1+ transition as well as IL-15-induced expansion of NKT cells.

European journal of immunology 20081201

Phosphorylation of nucleosides and nucleotides with inorganic monoimido-cyclo-triphosphate.

Chemical & pharmaceutical bulletin 20081201

[In-vitro screening of psychoactive drugs to prevent abuses].

Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 20081201

Role of iNO in the modulation of pulmonary vascular resistance.

Journal of perinatology : official journal of the California Perinatal Association 20081201

The stringent response and cell cycle arrest in Escherichia coli.

PLoS genetics 20081201

Chronic voluntary ethanol intake hypersensitizes 5-HT(1A) autoreceptors in C57BL/6J mice.

Journal of neurochemistry 20081201

ABCD of the phosphodiesterase family: interaction and differential activity in COPD.

International journal of chronic obstructive pulmonary disease 20081201

Mycophenolate mofetil for myasthenia gravis: a clear and present controversy.

Neuropsychiatric disease and treatment 20081201

Virologic, serologic, and biochemical outcomes through 2 years of treatment with entecavir and lamivudine in nucleoside-naïve Chinese patients with chronic hepatitis B: a randomized, multicenter study.

Hepatology international 20081201

Kap95p binding induces the switch loops of RanGDP to adopt the GTP-bound conformation: implications for nuclear import complex assembly dynamics.

Journal of molecular biology 20081121

Crystal structure of tRNA N2,N2-guanosine dimethyltransferase Trm1 from Pyrococcus horikoshii.

Journal of molecular biology 20081121

High resolution mass spectrometry for studying the interactions of cisplatin with oligonucleotides.

Inorganic chemistry 20081117

Genetic and biochemical analysis of yeast and human cap trimethylguanosine synthase: functional overlap of 2,2,7-trimethylguanosine caps, small nuclear ribonucleoprotein components, pre-mRNA splicing factors, and RNA decay pathways.

The Journal of biological chemistry 20081114

Inactive and active states of the interferon-inducible resistance GTPase, Irga6, in vivo.

The Journal of biological chemistry 20081114

The antiherpetic drug acyclovir inhibits HIV replication and selects the V75I reverse transcriptase multidrug resistance mutation.

The Journal of biological chemistry 20081114

A naloxonazine sensitive (mu1 receptor) mechanism in the parabrachial nucleus modulates eating.

Brain research 20081113

Polyphosphatase activity of CthTTM, a bacterial triphosphate tunnel metalloenzyme.

The Journal of biological chemistry 20081107

Inhibition of dicing of guanosine-rich shRNAs by quadruplex-binding compounds.

Chembiochem : a European journal of chemical biology 20081103

Mycophenolic acid inhibits cell proliferation and extracellular matrix synthesis in rat vascular smooth muscle cells through direct and indirect inhibition of cellular reactive oxygen species.

The Journal of surgical research 20081101

A molecular model of a putative substrate releasing conformation of multidrug resistance protein 5 (MRP5).

European journal of medicinal chemistry 20081101

Time-limited hyporesponsiveness to inhaled nitric oxide and pulmonary phosphodiesterase activity in endotoxemic rats.

The Journal of surgical research 20081101

G protein coupling and signaling pathway activation by m1 muscarinic acetylcholine receptor orthosteric and allosteric agonists.

The Journal of pharmacology and experimental therapeutics 20081101

N-arachidonyl maleimide potentiates the pharmacological and biochemical effects of the endocannabinoid 2-arachidonylglycerol through inhibition of monoacylglycerol lipase.

The Journal of pharmacology and experimental therapeutics 20081101

Metabolomic analyses of body fluids after subchronic manganese inhalation in rhesus monkeys.

Toxicological sciences : an official journal of the Society of Toxicology 20081101

Morphine desensitization, internalization, and down-regulation of the mu opioid receptor is facilitated by serotonin 5-hydroxytryptamine2A receptor coactivation.

Molecular pharmacology 20081101

Characteristics and modifying factors of asbestos-induced oxidative DNA damage.

Cancer science 20081101

In vitro nonenzymatic glycation of guanosine 5'-triphosphate by dihydroxyacetone phosphate.

Analytical and bioanalytical chemistry 20081101

Renal proximal tubules from old Fischer 344 rats grow into epithelial cells in cultures and exhibit increased oxidative stress and reduced D1 receptor function.

American journal of physiology. Cell physiology 20081101

Advanced glycation end products of DNA: quantification of N2-(1-Carboxyethyl)-2'-deoxyguanosine in biological samples by liquid chromatography electrospray ionization tandem mass spectrometry.

Chemical research in toxicology 20081101

Effect of NMSO3 treatment in a murine model of human metapneumovirus infection.

The Journal of general virology 20081101

Bryostatin-5 blocks stromal cell-derived factor-1 induced chemotaxis via desensitization and down-regulation of cell surface CXCR4 receptors.

Cancer research 20081101

Influence of cyclic guanosine 3',5' monophosphate modulators on muscle contraction of rat aortas.

Saudi medical journal 20081101

S-nitrosylation of surfactant protein-D controls inflammatory function.

PLoS biology 20081101

Hyperglycemia induces oxidative and nitrosative stress and increases renal functional impairment in Nrf2-deficient mice.

Genes to cells : devoted to molecular & cellular mechanisms 20081101

rac regulates its effector phospholipase Cgamma2 through interaction with a split pleckstrin homology domain.

The Journal of biological chemistry 20081031

Prolonged signaling at the parathyroid hormone receptor by peptide ligands targeted to a specific receptor conformation.

Proceedings of the National Academy of Sciences of the United States of America 20081028

Protein kinase G-dependent cardioprotective mechanism of phosphodiesterase-5 inhibition involves phosphorylation of ERK and GSK3beta.

The Journal of biological chemistry 20081024

A novel mechanism of G protein-coupled receptor functional selectivity. Muscarinic partial agonist McN-A-343 as a bitopic orthosteric/allosteric ligand.

The Journal of biological chemistry 20081024

Effect of the ribose versus 2'-deoxyribose residue on the metal ion-binding properties of purine nucleotides.

Dalton transactions (Cambridge, England : 2003) 20081021

Innate immunity in Caenorhabditis elegans is regulated by neurons expressing NPR-1/GPCR.

Science (New York, N.Y.) 20081017

A simple cytosine to G-clamp nucleobase substitution enables chiral gamma-PNAs to invade mixed-sequence double-helical B-form DNA.

Chembiochem : a European journal of chemical biology 20081013

Small molecule-induced allosteric activation of the Vibrio cholerae RTX cysteine protease domain.

Science (New York, N.Y.) 20081010

Antinociceptive effects of intracerebroventricular administration of guanine-based purines in mice: evidences for the mechanism of action.

Brain research 20081009

Recognition of the activated states of Galpha13 by the rgRGS domain of PDZRhoGEF.

Structure (London, England : 1993) 20081008

mGluR7 facilitates extinction of aversive memories and controls amygdala plasticity.

Molecular psychiatry 20081001

Inhibitory effects of quercetin derivatives on phosphodiesterase isozymes and high-affinity [(3) H]-rolipram binding in guinea pig tissues.

Investigational new drugs 20081001

In vivo characterization of (-)(-)MCL-144 and (+)(-)MCL-193: isomeric, bivalent ligands with mu/kappa agonist properties.

Neurochemical research 20081001

Structural motifs of importance for the constitutive activity of the orphan 7TM receptor EBI2: analysis of receptor activation in the absence of an agonist.

Molecular pharmacology 20081001

Genetic evidence for the essential role of PfNT1 in the transport and utilization of xanthine, guanine, guanosine and adenine by Plasmodium falciparum.

Molecular and biochemical parasitology 20081001

Electroanalytical study of proflavine intercalation in 5-methyl or inosine-containing amplicons.

Analytical and bioanalytical chemistry 20081001

Serotonin increases GABA release in rat entorhinal cortex by inhibiting interneuron TASK-3 K+ channels.

Molecular and cellular neurosciences 20081001

Dopamine D1 receptor inhibition of NMDA receptor currents mediated by tyrosine kinase-dependent receptor trafficking in neonatal rat striatum.

The Journal of physiology 20081001

Changes in the rewarding effects induced by tramadol and its active metabolite M1 after sciatic nerve injury in mice.

Psychopharmacology 20081001

Effects of N2,N2-dimethylguanosine on RNA structure and stability: crystal structure of an RNA duplex with tandem m2 2G:A pairs.

RNA (New York, N.Y.) 20081001

TRAMP-mediated RNA surveillance prevents spurious entry of RNAs into the Schizosaccharomyces pombe siRNA pathway.

Nature structural & molecular biology 20081001

Labelling and biological evaluation of [(11)C]methoxy-Sch225336: a radioligand for the cannabinoid-type 2 receptor.

Nuclear medicine and biology 20081001

Pharmacokinetics of guanosine in rats following intravenous or intramuscular administration of a 1:1 mixture of guanosine and acriflavine, a potential antitumor agent.

Archives of pharmacal research 20081001

Receptor-mediated changes at the myristoylated amino terminus of Galpha(il) proteins.

Biochemistry 20080930

Arabidopsis nucleoside diphosphate kinase-2 as a plant GTPase activating protein.

BMB reports 20080930

Crystal structure of the Thermus thermophilus 16 S rRNA methyltransferase RsmC in complex with cofactor and substrate guanosine.

The Journal of biological chemistry 20080926

Density functional theory calculations of hydrogen-bond-mediated NMR J coupling in the solid state.

Journal of the American Chemical Society 20080924

Activating parabrachial cannabinoid CB1 receptors selectively stimulates feeding of palatable foods in rats.

The Journal of neuroscience : the official journal of the Society for Neuroscience 20080924

Purification and mass spectrometric analysis of the kappa opioid receptor.

Brain research 20080916

Structure of the 1,N2-ethenodeoxyguanosine adduct opposite cytosine in duplex DNA: Hoogsteen base pairing at pH 5.2.

Chemical research in toxicology 20080915

N2-functionalized blue luminescent guanosines by 2,2'-dipyridylamino and 2-(2'-pyridyl)benzimidazolyl chelate groups and their interactions with Zn(II) ions.

Inorganic chemistry 20080915

Redesigned tetrads with altered hydrogen bonding patterns enable programming of quadruplex topologies.

Chemical communications (Cambridge, England) 20080914

Structures of substrate- and inhibitor-bound adenosine deaminase from a human malaria parasite show a dramatic conformational change and shed light on drug selectivity.

Journal of molecular biology 20080912

Effects of sample preparation methods on the quantification of nucleosides in natural and cultured Cordyceps.

Journal of pharmaceutical and biomedical analysis 20080910

Oxidized phospholipid inhibition of toll-like receptor (TLR) signaling is restricted to TLR2 and TLR4: roles for CD14, LPS-binding protein, and MD2 as targets for specificity of inhibition.

The Journal of biological chemistry 20080905

Interconversion of the cis-5R,6S- and trans-5R,6R-thymine glycol lesions in duplex DNA.

Journal of the American Chemical Society 20080903

Crystal structure of archaeal tRNA(m(1)G37)methyltransferase aTrm5.

Proteins 20080901

Studies on DNA-binding selectivity of WRKY transcription factors lend structural clues into WRKY-domain function.

Plant molecular biology 20080901

Functional reconstitution of the human chemokine receptor CXCR4 with G(i)/G (o)-proteins in Sf9 insect cells.

Naunyn-Schmiedeberg's archives of pharmacology 20080901

Expression profiling of four RelA/SpoT-like proteins, homologues of bacterial stringent factors, in Arabidopsis thaliana.

Planta 20080901

Carbon monoxide and nitric oxide mediate cytoskeletal reorganization in microvascular cells via vasodilator-stimulated phosphoprotein phosphorylation: evidence for blunted responsiveness in diabetes.

Diabetes 20080901

Evidence for interindividual heterogeneity in the glucose gradient across the human red blood cell membrane and its relationship to hemoglobin glycation.

Diabetes 20080901

Effect of Maillard reacted peptides on human salt taste and the amiloride-insensitive salt taste receptor (TRPV1t).

Chemical senses 20080901

Nitric oxide-cGMP-protein kinase G pathway negatively regulates vascular transient receptor potential channel TRPC6.

The Journal of physiology 20080901

Expression and hepatobiliary transport characteristics of the concentrative and equilibrative nucleoside transporters in sandwich-cultured human hepatocytes.

American journal of physiology. Gastrointestinal and liver physiology 20080901

Synthesis and application of a new 2',3'-isopropylidene guanosine substituted cap analog.

Bioorganic & medicinal chemistry letters 20080901

Process research on the preparation of DMT protected 2'-O-methoxyethylguanosine for oligonucleotide synthesis in therapeutic applications.

Nucleosides, nucleotides & nucleic acids 20080901

Involvement of kappa opioid receptors in the inhibition of receptor desensitization and PKC activation induced by repeated morphine treatment.

The Journal of pharmacy and pharmacology 20080901

Effects of mycophenolic acid on human fibroblast proliferation, migration and adhesion in vitro and in vivo.

American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20080901

Effect of COPD treatments on MRP1-mediated transport in bronchial epithelial cells.

International journal of chronic obstructive pulmonary disease 20080901

[Quantitative analysis of nucleotide mixtures with terahertz time domain spectroscopy].

Guang pu xue yu guang pu fen xi = Guang pu 20080901

Cellular and biochemical actions of melatonin which protect against free radicals: role in neurodegenerative disorders.

Current neuropharmacology 20080901

Determination of nucleotides in infant formula by ion-exchange liquid chromatography.

Journal of agricultural and food chemistry 20080827

Rab3GEP is the non-redundant guanine nucleotide exchange factor for Rab27a in melanocytes.

The Journal of biological chemistry 20080822

Mechanisms of lumbrokinase in protection of cerebral ischemia.

European journal of pharmacology 20080820

The RNA acetyltransferase driven by ATP hydrolysis synthesizes N4-acetylcytidine of tRNA anticodon.

The EMBO journal 20080820

Overexpression of human OGG1 in mammalian cells decreases ultraviolet A induced mutagenesis.

Cancer letters 20080818

A flexible loop as a functional element in the catalytic mechanism of nucleoside hydrolase from Trypanosoma vivax.

The Journal of biological chemistry 20080808

Evidence for two distinct Mg2+ binding sites in G(s alpha) and G(i alpha1) proteins.

Biochemical and biophysical research communications 20080808

Human CHN1 mutations hyperactivate alpha2-chimaerin and cause Duane's retraction syndrome.

Science (New York, N.Y.) 20080808

Formation of tricyclic [4.3.3.0] adducts between 8-oxoguanosine and tyrosine under conditions of oxidative DNA-protein cross-linking.

Journal of the American Chemical Society 20080806

Characterization of umami receptor and coupling G protein in mouse taste cells.

Neuroreport 20080806

Guanosine and its modulatory effects on the glutamatergic system.

European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology 20080801

HPLC-fluorescence assay for acyclovir in children.

Biomedical chromatography : BMC 20080801

Dysregulation of nociceptin/orphanin FQ activity in the amygdala is linked to excessive alcohol drinking in the rat.

Biological psychiatry 20080801

Molecular mechanisms of PLD function in membrane traffic.

Traffic (Copenhagen, Denmark) 20080801

Investigation into A antigen expression on O2 heterozygous group O-labeled red blood cell units.

Transfusion 20080801

Caspase cleavage of phospholipase D1 in vitro alters its regulation and reveals a novel property of the 'loop' region.

Biochimica et biophysica acta 20080801

Suppression of grasshopper sound production by nitric oxide-releasing neurons of the central complex.

Journal of comparative physiology. A, Neuroethology, sensory, neural, and behavioral physiology 20080801

Conformationally restricted nucleotides as a probe of structure-function relationships in RNA.

RNA (New York, N.Y.) 20080801

Regulation of the RelA (p65) transactivation domain.

Biochemical Society transactions 20080801

Neuropeptide Y receptors in primary human brain tumors: overexpression in high-grade tumors.

Journal of neuropathology and experimental neurology 20080801

Some selective serotonin reuptake inhibitors inhibit dynamin I guanosine triphosphatase (GTPase).

Biological & pharmaceutical bulletin 20080801

High-precision, whole-genome sequencing of laboratory strains facilitates genetic studies.

PLoS genetics 20080801

Decrease of D2 receptor binding but increase in D2-stimulated G-protein activation, dopamine transporter binding and behavioural sensitization in brains of mice treated with a chronic escalating dose 'binge' cocaine administration paradigm.

The European journal of neuroscience 20080801

Photophysical characterization and photodynamic activity of metallo 5-(4-(trimethylammonium)phenyl)-10,15,20-tris(2,4,6-trimethoxyphenyl)porphyrin in homogeneous and biomimetic media.

Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology 20080801

Coordinate regulation of G protein signaling via dynamic interactions of receptor and GAP.

PLoS computational biology 20080801

An enzymatic atavist revealed in dual pathways for water activation.

PLoS biology 20080801

Dendritic cells stimulated with cytidine-phosphate-guanosine oligodeoxynucleotides and interferon-alpha-expressing tumor cells effectively reduce outgrowth of established tumors in vivo.

Cancer science 20080801

A preliminary report of the dopamine receptor D(4) and the dopamine transporter 1 gene polymorphism and its association with attention deficit hyperactivity disorder.

Neuropsychiatric disease and treatment 20080801

Pegylated interferon 2a and 2b in combination with ribavirin for the treatment of chronic hepatitis C in HIV infected patients.

Therapeutics and clinical risk management 20080801

G protein activation by the leukotriene B4 receptor dimer. Evidence for an absence of trans-activation.

The Journal of biological chemistry 20080725

Identification of farnesyl pyrophosphate and N-arachidonylglycine as endogenous ligands for GPR92.

The Journal of biological chemistry 20080725

Human polynucleotide phosphorylase reduces oxidative RNA damage and protects HeLa cell against oxidative stress.

Biochemical and biophysical research communications 20080725

Changes in conformational dynamics of mRNA upon AtGRP7 binding studied by fluorescence correlation spectroscopy.

Journal of the American Chemical Society 20080723

The 2'-hydroxyl group of the guanosine nucleophile donates a functionally important hydrogen bond in the tetrahymena ribozyme reaction.

Biochemistry 20080722

13C relaxation studies of the DNA target sequence for hhai methyltransferase reveal unique motional properties.

Biochemistry 20080722

Discovery of potent CCR4 antagonists: Synthesis and structure-activity relationship study of 2,4-diaminoquinazolines.

Bioorganic & medicinal chemistry 20080715

Superior removal of hydantoin lesions relative to other oxidized bases by the human DNA glycosylase hNEIL1.

Biochemistry 20080708

Effects of the G(-656)A variant on CREB1 promoter activity in a glial cell line: interactions with gonadal steroids and stress.

American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics 20080705

Photocleavable initiator nucleotide substrates for an aldolase ribozyme.

The Journal of organic chemistry 20080704

Synthesis of a stabilized version of the imidazolone DNA lesion.

Chembiochem : a European journal of chemical biology 20080702

Structural basis of thiamine pyrophosphate analogues binding to the eukaryotic riboswitch.

Journal of the American Chemical Society 20080702

Celecoxib-induced growth inhibition in SW480 colon cancer cells is associated with activation of protein kinase G.

Molecular carcinogenesis 20080701

TRPC5 channels undergo changes in gating properties during the activation-deactivation cycle.

Journal of cellular physiology 20080701

Norepinephrine-mediated regulation of 5HT1 receptor functioning in human platelets.

Neurochemical research 20080701

Silencing genes in the kidney: antisense or RNA interference?

Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20080701

Synthesis of 1-beta-D-ribofuranosyl-3-ethynyl-[1,2,4]triazole and its in vitro and in vivo efficacy against Hantavirus.

Antiviral research 20080701

miRNAs at the heart of the matter.

Journal of molecular medicine (Berlin, Germany) 20080701

High yield purification of soluble guanylate cyclase from bovine lung.

Protein expression and purification 20080701

Novobiocin inhibits the self-splicing of the primary transcripts of T4 phage thymidylate synthase gene.

Molecular and cellular biochemistry 20080701

Conformational change of the transmembrane helices II and IV of metabotropic glutamate receptor involved in G protein activation.

Journal of neurochemistry 20080701

Disruption of a Plasmodium falciparum cyclic nucleotide phosphodiesterase gene causes aberrant gametogenesis.

Molecular microbiology 20080701

Microfabricated channel array electrophoresis for characterization and screening of enzymes using RGS-G protein interactions as a model system.

Analytical chemistry 20080701

Effects of Delta9-tetrahydrocannabivarin on [35S]GTPgammaS binding in mouse brain cerebellum and piriform cortex membranes.

British journal of pharmacology 20080701

Long-term fasting decreases mitochondrial avian UCP-mediated oxygen consumption in hypometabolic king penguins.

American journal of physiology. Regulatory, integrative and comparative physiology 20080701

ATP/UTP activate cation-permeable channels with TRPC3/7 properties in rat cardiomyocytes.

American journal of physiology. Heart and circulatory physiology 20080701

High-content assay to study protein prenylation.

Journal of biomolecular screening 20080701

Mutation in the rel gene of Sorangium cellulosum affects morphological and physiological differentiation.

Molecular microbiology 20080701

Inhibition of fatty acid amide hydrolase and cyclooxygenase-2 increases levels of endocannabinoid related molecules and produces analgesia via peroxisome proliferator-activated receptor-alpha in a model of inflammatory pain.

Neuropharmacology 20080701

Membrane potential shifts caused by diffusible guidance signals direct growth-cone turning.

Nature neuroscience 20080701

A general method for phasing novel complex RNA crystal structures without heavy-atom derivatives.

Acta crystallographica. Section D, Biological crystallography 20080701

The role of G proteins in thromospondin-1-induced vascular smooth muscle cell migration.

Surgery 20080701

Design, synthesis, and actions of a novel chimeric natriuretic peptide: CD-NP.

Journal of the American College of Cardiology 20080701

Contribution of active and inactive states of the human 5-HT4d receptor to the functional activities of 5-HT4-receptor agonists.

Journal of pharmacological sciences 20080701

Activation of protein kinase G Increases the expression of p21CIP1, p27KIP1, and histidine triad protein 1 through Sp1.

Cancer research 20080701

Kinetic modeling of the assembly, dynamic steady state, and contraction of the FtsZ ring in prokaryotic cytokinesis.

PLoS computational biology 20080701

Brevetoxin forms covalent DNA adducts in rat lung following intratracheal exposure.

Environmental health perspectives 20080701

Miscoding properties of 6alpha- and 6beta-diastereoisomers of the N(2)-(estradiol-6-yl)-2'-deoxyguanosine DNA adduct by Y-family human DNA polymerases.

Biochemistry 20080624

Systematic deletion of the adenovirus-associated RNAI terminal stem reveals a surprisingly active RNA inhibitor of double-stranded RNA-activated protein kinase.

The Journal of biological chemistry 20080620

Liquid crystalline phase of G-tetrad DNA for NMR study of detergent-solubilized proteins.

Journal of the American Chemical Society 20080618

Differential induction of nitric oxide, degranulation, and oxidative burst activities in response to microbial agonist stimulations in monocytes and heterophils from young commercial turkeys.

Veterinary immunology and immunopathology 20080615

Expression and characterization of the human alpha 2B-adrenoceptor in a vascular smooth muscle cell line.

European journal of pharmacology 20080610

Morphine-nicotine interaction in conditioned place preference in mice after chronic nicotine exposure.

European journal of pharmacology 20080610

Synthesis of hydrophobic derivatives of the G/\C base for rosette nanotube self-assembly in apolar media.

The Journal of organic chemistry 20080606

Functional circularity of legitimate Qbeta replicase templates.

Journal of molecular biology 20080606

Interactions of guanine and guanosine hydrates with quinones: a laser flash photolysis and magnetic field effect study.

The journal of physical chemistry. A 20080605

Analyzing and modeling the inhibitory effect of phosphatidic acid on the GTP-gamma-S binding activity of Goalpha.

Proteins 20080601

Stacking efficiency and flexibility analysis of aromatic amino acids in cap-binding proteins.

Proteins 20080601

Antibodies that identify only the active conformation of G(i) family G protein alpha subunits.

FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20080601

Simple HPLC-UV determination of nucleosides and its application to the authentication of Cordyceps and its allies.

Biomedical chromatography : BMC 20080601

Assessment of nerve stimulation-induced release of purines from mouse kidneys by tandem mass spectrometry.

The Journal of pharmacology and experimental therapeutics 20080601

Pharmacological assessment of m1 muscarinic acetylcholine receptor-gq/11 protein coupling in membranes prepared from postmortem human brain tissue.

The Journal of pharmacology and experimental therapeutics 20080601

Peculiar mechanistic and structural features of the carboplatin-cytochrome c system revealed by ESI-MS analysis.

Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry 20080601

Insulin-like growth factor-1 restores erectile function in aged rats: modulation the integrity of smooth muscle and nitric oxide-cyclic guanosine monophosphate signaling activity.

The journal of sexual medicine 20080601

GTP avoidance in Tetrahymena thermophila requires tyrosine kinase activity, intracellular calcium, NOS, and guanylyl cyclase.

Purinergic signalling 20080601

Reciprocal inhibition of G-protein signaling is induced by CB(1) cannabinoid and GABA(B) receptor interactions in rat hippocampal membranes.

Neurochemistry international 20080601

Characterization of phosphate-containing metabolites by calcium adduction and electron capture dissociation.

Journal of the American Society for Mass Spectrometry 20080601

A purine-selective nucleobase/nucleoside transporter in PK15NTD cells.

American journal of physiology. Regulatory, integrative and comparative physiology 20080601

Characterization of Aquifex aeolicus 4-diphosphocytidyl-2C-methyl-d-erythritol kinase - ligand recognition in a template for antimicrobial drug discovery.

The FEBS journal 20080601

Nucleoside composition of Heloderma venoms.

Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology 20080601

Synthesis and characterization of mRNA cap analogs containing phosphorothioate substitutions that bind tightly to eIF4E and are resistant to the decapping pyrophosphatase DcpS.

RNA (New York, N.Y.) 20080601

Oxidative stress impairs the repair of oxidative DNA base modifications in human skin fibroblasts and melanoma cells.

DNA repair 20080601

Role of oxidative stress in high glucose-induced decreased expression of Gialpha proteins and adenylyl cyclase signaling in vascular smooth muscle cells.

American journal of physiology. Heart and circulatory physiology 20080601

Recruitment of beta-arrestin2 to the dopamine D2 receptor: insights into anti-psychotic and anti-parkinsonian drug receptor signaling.

Neuropharmacology 20080601

Interactions of nucleosides with CrO(4) (2-) and Cr(3+) as studied by electrospray ionization mass spectrometry.

Rapid communications in mass spectrometry : RCM 20080601

Kinetic characterization of the first step of the ribozyme-catalyzed trans excision-splicing reaction.

The FEBS journal 20080601

Metabonomics in cancer diagnosis: mass spectrometry-based profiling of urinary nucleosides from breast cancer patients.

Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals 20080601

TLR Ligand-Induced Type I IFNs Affect Thymopoiesis.

Journal of immunology (Baltimore, Md. : 1950) 20080601

Analysis of the neuroinflammatory response to TLR7 stimulation in the brain: comparison of multiple TLR7 and/or TLR8 agonists.

Journal of immunology (Baltimore, Md. : 1950) 20080601

The spinal antinociceptive effects of endomorphins in rats: behavioral and G protein functional studies.

Anesthesia and analgesia 20080601

High-throughput screening of novel antagonists on melanin-concentrating hormone receptor-1.

Acta pharmacologica Sinica 20080601

Pharmacological characterization of alpha2D-adrenergic receptor-mediated [35S]GTPgammaS binding in rat cerebral cortical membranes.

Pharmacological research 20080601

Downregulation of the Escherichia coli guaB promoter by FIS.

Microbiology (Reading, England) 20080601

Gametogenesis in malaria parasites is mediated by the cGMP-dependent protein kinase.

PLoS biology 20080601

A 1,536-well [(35)S]GTPgammaS scintillation proximity binding assay for ultra-high-throughput screening of an orphan galphai-coupled GPCR.

Assay and drug development technologies 20080601

Concepts of neural nitric oxide-mediated transmission.

The European journal of neuroscience 20080601

Group II intron protein localization and insertion sites are affected by polyphosphate.

PLoS biology 20080601

A robust and high-capacity [(35)S]GTPgammaS binding assay for determining antagonist and inverse agonist pharmacological parameters of histamine H(3) receptor ligands.

Assay and drug development technologies 20080601

Neurotrophic effects of extracellular guanosine.

Nucleosides, nucleotides & nucleic acids 20080601

Metabolism and distribution of guanosine given intraperitoneally: implications for spinal cord injury.

Nucleosides, nucleotides & nucleic acids 20080601

Electrochemical Investigation of oligonucleotide-DNA hybridization on poly(4-methoxyphenethylamine).

International journal of molecular sciences 20080601

Tea polyphenols and their roles in cancer prevention and chemotherapy.

International journal of molecular sciences 20080601

Key labeling technologies to tackle sizeable problems in RNA structural biology.

International journal of molecular sciences 20080601

Crystal structure of Escherichia coli MazG, the regulator of nutritional stress response.

The Journal of biological chemistry 20080530

Quantum dot nanocrystals having guanosine imprinted nanoshell for DNA recognition.

Talanta 20080530

Guanosine promotes B16F10 melanoma cell differentiation through PKC-ERK 1/2 pathway.

Chemico-biological interactions 20080528

Rv2131c from Mycobacterium tuberculosis is a CysQ 3'-phosphoadenosine-5'-phosphatase.

Biochemistry 20080527

Characterization of the Arabidopsis heterotrimeric G protein.

The Journal of biological chemistry 20080516

Energization-dependent endogenous activation of proton conductance in skeletal muscle mitochondria.

The Biochemical journal 20080515

Synthesis and biochemical application of 2'-O-methyl-3'-thioguanosine as a probe to explore group I intron catalysis.

Bioorganic & medicinal chemistry 20080515

Tonic and stimulus-evoked nitric oxide production in the mouse olfactory bulb.

Neuroscience 20080515

Simultaneous determination of aciclovir, ganciclovir, and penciclovir in human plasma by high-performance liquid chromatography with fluorescence detection.

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20080515

Fhit-deficient hematopoietic stem cells survive hydroquinone exposure carrying precancerous changes.

Cancer research 20080515

Characterization of an orphan G protein-coupled receptor, GPR20, that constitutively activates Gi proteins.

The Journal of biological chemistry 20080509

Unexpected suppression of neuronal G protein-activated, inwardly rectifying K+ current by common phospholipase C inhibitor.

Neuroscience letters 20080509

Degradation of bidentate-coordinated platinum(II)-based DNA intercalators by reduced L-glutathione.

Journal of medicinal chemistry 20080508

Regulator of G-protein signaling subtype 4 mediates antihypertrophic effect of locally secreted natriuretic peptides in the heart.

Circulation 20080506

Cisplatin-DNA adduct formation in patients treated with cisplatin-based chemoradiation: lack of correlation between normal tissues and primary tumor.

Cancer chemotherapy and pharmacology 20080501

Agonist and antagonist properties of antipsychotics at human dopamine D4.4 receptors: G-protein activation and K+ channel modulation in transfected cells.

The international journal of neuropsychopharmacology 20080501

Kinetic and mutational analysis of the Trypanosoma brucei NBT1 nucleobase transporter expressed in Saccharomyces cerevisiae reveals structural similarities between ENT and MFS transporters.

International journal for parasitology 20080501

Effects of chronic treatment with citalopram on cannabinoid and opioid receptor-mediated G-protein coupling in discrete rat brain regions.

Psychopharmacology 20080501

Allosteric ligands for the corticotropin releasing factor type 1 receptor modulate conformational states involved in receptor activation.

Molecular pharmacology 20080501

Suppression of NO production and 8-nitroguanosine formation by phenol-containing endocrine-disrupting chemicals in LPS-stimulated macrophages: involvement of estrogen receptor-dependent or -independent pathways.

Nitric oxide : biology and chemistry 20080501

Endogenous regulators of G protein signaling differentially modulate full and partial mu-opioid agonists at adenylyl cyclase as predicted by a collision coupling model.

Molecular pharmacology 20080501

PMA counteracts G protein actions on CaV2.2 channels in rat sympathetic neurons.

Archives of biochemistry and biophysics 20080501

17beta-Oestradiol stimulation of G-proteins in aged and Alzheimer's human brain: comparison with phytoestrogens.

Journal of neuroendocrinology 20080501

Molecular modeling and dynamics simulations of PNP from Streptococcus agalactiae.

Bioorganic & medicinal chemistry 20080501

Supersensitivity to mu-opioid receptor-mediated inhibition of the adenylyl cyclase pathway involves pertussis toxin-resistant Galpha protein subunits.

Neuropharmacology 20080501

A cation-directed switch of intermolecular spin-spin interaction of guanosine derivatives functionalized with open-shell units.

Organic letters 20080501

A coarse-grained biophysical model of E. coli and its application to perturbation of the rRNA operon copy number.

PLoS computational biology 20080501

Human atrial natriuretic peptide suppresses torsades de pointes in rabbits.

Circulation journal : official journal of the Japanese Circulation Society 20080501

The acidic tumor microenvironment promotes the reconversion of nitrite into nitric oxide: towards a new and safe radiosensitizing strategy.

Clinical cancer research : an official journal of the American Association for Cancer Research 20080501

Direct effects of riluzole on 5-hydroxytryptamine (5-HT)3 receptor-activated ion currents in NCB-20 neuroblastoma cells.

Journal of pharmacological sciences 20080501

Separation properties of novel and commercial polar stationary phases in hydrophilic interaction and reversed-phase liquid chromatography mode.

Journal of separation science 20080501

Rapid changes in hippocampal CA1 pyramidal cell function via pre- as well as postsynaptic membrane mineralocorticoid receptors.

The European journal of neuroscience 20080501

LPK-26, a novel kappa-opioid receptor agonist with potent antinociceptive effects and low dependence potential.

European journal of pharmacology 20080428

Constitutive activity of the cannabinoid CB1 receptor regulates the function of co-expressed Mu opioid receptors.

The Journal of biological chemistry 20080425

Direct evidence for the involvement of endogenous beta-endorphin in the suppression of the morphine-induced rewarding effect under a neuropathic pain-like state.

Neuroscience letters 20080425

A Pneumocystis carinii group I intron-derived ribozyme utilizes an endogenous guanosine as the first reaction step nucleophile in the trans excision-splicing reaction.

Biochemistry 20080422

2'-Deoxyimmunosine: stereoselective synthesis, base pairing and duplex stability of oligonucleotides containing 8-oxo-7-thiaguanine.

Organic & biomolecular chemistry 20080421

Mutagenicity of 8-nitroguanosine, a product of nitrative nucleoside modification by reactive nitrogen oxides, in mammalian cells.

Cancer letters 20080418

An exploration of mechanisms for the transformation of 8-oxoguanine to guanidinohydantoin and spiroiminodihydantoin by density functional theory.

Journal of the American Chemical Society 20080416

Compensatory and long-range changes in picosecond-nanosecond main-chain dynamics upon complex formation: 15N relaxation analysis of the free and bound states of the ubiquitin-like domain of human plexin-B1 and the small GTPase Rac1.

Journal of molecular biology 20080411

Evolution of class-specific peptides targeting a hot spot of the Galphas subunit.

Journal of molecular biology 20080411

Rats with high or low sociability are differently affected by chronic variable stress.

Neuroscience 20080409

Conformer distribution in (cis-1,4-DACH)bis(guanosine-5'-phosphate)platinum(II) adducts: a reliable model for DNA adducts of antitumoral cisplatin.

Inorganic chemistry 20080407

Comparative pharmacological profiles of morphine and oxycodone under a neuropathic pain-like state in mice: evidence for less sensitivity to morphine.

Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20080401

Guanosine possesses specific modulatory effects on NMDA receptor-mediated neurotransmission in intact mice.

European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology 20080401

Exogenous nucleosides accelerate differentiation of rat intestinal epithelial cells.

The British journal of nutrition 20080401

Influence of positive allosteric modulators on GABA(B) receptor coupling in rat brain: a scintillation proximity assay characterisation of G protein subtypes.

Journal of neurochemistry 20080401

Rho kinase is involved in Ca2+ entry of rat penile small arteries.

American journal of physiology. Heart and circulatory physiology 20080401

Up-regulation of adenosine receptors in the frontal cortex in Alzheimer's disease.

Brain pathology (Zurich, Switzerland) 20080401

Highly pathogenic RNA viral infections: challenges for antiviral research.

Antiviral research 20080401

Purine alkaloids from the South China Sea gorgonian Subergorgia suberosa.

Journal of natural products 20080401

Fetal haemoglobin response to hydroxycarbamide treatment and sar1a promoter polymorphisms in sickle cell anaemia.

British journal of haematology 20080401

Sex-dependent effects of periadolescent exposure to the cannabinoid agonist CP-55,940 on morphine self-administration behaviour and the endogenous opioid system.

Neuropharmacology 20080401

MT1 melatonin receptor internalization underlies melatonin-induced morphologic changes in Chinese hamster ovary cells and these processes are dependent on Gi proteins, MEK 1/2 and microtubule modulation.

Journal of pineal research 20080401

The effect of sildenafil on ocular blood flow.

The British journal of ophthalmology 20080401

Screening of anti-platelet aggregation agents from Panax notoginseng using human platelet extraction and HPLC-DAD-ESI-MS/MS.

Journal of separation science 20080401

Cloning, purification, and polymerization of Capsicum annuum recombinant alpha and beta tubulin.

Bioscience, biotechnology, and biochemistry 20080401

Darwinian evolution on a chip.

PLoS biology 20080401

High-throughput SHAPE analysis reveals structures in HIV-1 genomic RNA strongly conserved across distinct biological states.

PLoS biology 20080401

Role of phosphodiesterase 5 in synaptic plasticity and memory.

Neuropsychiatric disease and treatment 20080401

Treating refractory leukemias in childhood, role of clofarabine.

Therapeutics and clinical risk management 20080401

Single-day treatment for orolabial and genital herpes: a brief review of pathogenesis and pharmacology.

Therapeutics and clinical risk management 20080401

Novel D-amino acid tetrapeptides produce potent antinociception by selectively acting at peripheral kappa-opioid receptors.

European journal of pharmacology 20080331

Differential regulation of serotonin-1A receptor-stimulated [35S]GTP gamma S binding in the dorsal raphe nucleus by citalopram and escitalopram.

European journal of pharmacology 20080331

Methadone: does it really have low efficacy at micro-opioid receptors?

Neuroreport 20080326

Preparation and purification of 5'-amino-5'-deoxyguanosine-5'-N-phosphoramidate and its initiation properties with T7 RNA polymerase.

Organic & biomolecular chemistry 20080321

High-performance liquid chromatography determination of 5-methyl-2'-deoxycytidine, 2'-deoxycytidine, and other deoxynucleosides and nucleosides in DNA digests.

Analytical biochemistry 20080315

Genetic variation and response to morphine in cancer patients: catechol-O-methyltransferase and multidrug resistance-1 gene polymorphisms are associated with central side effects.

Cancer 20080315

Novel trans-3,4-dimethyl-4-(3-hydroxyphenyl)piperidines as mu opioid receptor antagonists with improved opioid receptor selectivity profiles.

Bioorganic & medicinal chemistry letters 20080315

Large and stable transmembrane pores from guanosine-bile acid conjugates.

Journal of the American Chemical Society 20080312

Synthesis of guanosine 5'-conjugates and their use as initiator molecules for transcription priming.

Organic & biomolecular chemistry 20080307

Electron transfer between guanosine radicals and amino acids in aqueous solution. II. Reduction of guanosine radicals by tryptophan.

The journal of physical chemistry. B 20080306

Structural changes of eIF4E upon binding to the mRNA 5' monomethylguanosine and trimethylguanosine Cap.

Biochemistry 20080304

Meeting report: cGMP matters.

Science signaling 20080304

Chronic morphine use does not induce peripheral tolerance in a rat model of inflammatory pain.

The Journal of clinical investigation 20080303

Impairment of muscarinic transmission in transgenic APPswe/PS1dE9 mice.

Neurobiology of aging 20080301

Alpha 2A-adrenoceptor-specific stimulation of [35S]GTP gamma S binding to membrane preparations of rat frontal cortex.

Neurochemical research 20080301

The use of circular dichroism spectroscopy for studying the chiral molecular self-assembly: an overview.

Chirality 20080301

Molecular characterization of vibrio cholerae DeltarelA DeltaspoT double mutants.

Archives of microbiology 20080301

Feedback control of ribosome function in Escherichia coli.

Biochimie 20080301

Roles of Rho guanosine 5'-triphosphatase A, Rho kinases, and extracellular signal regulated kinase (1/2) in prostaglandin E2-mediated migration of first-trimester human extravillous trophoblast.

Endocrinology 20080301

Morphine-induced analgesic tolerance, locomotor sensitization and physical dependence do not require modification of mu opioid receptor, cdk5 and adenylate cyclase activity.

Neuropharmacology 20080301

2-Methoxymethyl-salvinorin B is a potent kappa opioid receptor agonist with longer lasting action in vivo than salvinorin A.

The Journal of pharmacology and experimental therapeutics 20080301

Characterization of the molecular fragment that is responsible for agonism of pergolide at serotonin 5-Hydroxytryptamine2B and 5-Hydroxytryptamine2A receptors.

The Journal of pharmacology and experimental therapeutics 20080301

Characterization of epoxyeicosatrienoic acid binding site in U937 membranes using a novel radiolabeled agonist, 20-125i-14,15-epoxyeicosa-8(Z)-enoic acid.

The Journal of pharmacology and experimental therapeutics 20080301

Low-fat diet and exercise preserve eNOS regulation and endothelial function in the penis of early atherosclerotic pigs: a molecular analysis.

The journal of sexual medicine 20080301

Quantification and comparison of toll-like receptor expression and responsiveness in primary and immortalized human female lower genital tract epithelia.

American journal of reproductive immunology (New York, N.Y. : 1989) 20080301

Neuroanatomical mapping of juvenile rat brain regions with prominent basal signal in [(35)S]GTPgammaS autoradiography.

Journal of chemical neuroanatomy 20080301

GTPgammaS incorporation in the rat brain: a study on mu-opioid receptors and CXCR4.

Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology 20080301

Enhanced NMR signal detection of imino protons in RNA molecules containing 3' dangling nucleotides.

Journal of biomolecular NMR 20080301

Role of redox signaling and poly (adenosine diphosphate-ribose) polymerase activation in vascular smooth muscle cell growth inhibition by nitric oxide and peroxynitrite.

Journal of vascular surgery 20080301

Streptomyces clavuligerus relA-null mutants overproduce clavulanic acid and cephamycin C: negative regulation of secondary metabolism by (p)ppGpp.

Microbiology (Reading, England) 20080301

Rho GTPase activation assays.

Current protocols in cell biology 20080301

Phosphorylation-independent regulation of the diguanylate cyclase WspR.

PLoS biology 20080301

Remyelination after chronic spinal cord injury is associated with proliferation of endogenous adult progenitor cells after systemic administration of guanosine.

Purinergic signalling 20080301

Effect of locked-nucleic acid on a biologically active g-quadruplex. A structure-activity relationship of the thrombin aptamer.

International journal of molecular sciences 20080301

Unique agonist-bound cannabinoid CB1 receptor conformations indicate agonist specificity in signaling.

European journal of pharmacology 20080226

Antipsychotics differ in their ability to internalise human dopamine D2S and human serotonin 5-HT1A receptors in HEK293 cells.

European journal of pharmacology 20080226

Impact of the oxidized guanine lesion spiroiminodihydantoin on the conformation and thermodynamic stability of a 15-mer DNA duplex.

Biochemistry 20080226

Importance of platinum(II)-assisted platinum(IV) substitution for the oxidation of guanosine derivatives by platinum(IV) complexes.

Inorganic chemistry 20080218

Cellular nucleic acid binding protein binds G-rich single-stranded nucleic acids and may function as a nucleic acid chaperone.

Journal of cellular biochemistry 20080215

GTP up-regulated persistent Na+ current and enhanced nociceptor excitability require NaV1.9.

The Journal of physiology 20080215

Studies on umami taste. Synthesis of new guanosine 5'-phosphate derivatives and their synergistic effect with monosodium glutamate.

Journal of agricultural and food chemistry 20080213

Distribution of nucleosides and nucleobases in edible fungi.

Journal of agricultural and food chemistry 20080213

Hepatic oxidative DNA damage is associated with increased risk for hepatocellular carcinoma in chronic hepatitis C.

British journal of cancer 20080212

The TbMTr1 spliced leader RNA cap 1 2'-O-ribose methyltransferase from Trypanosoma brucei acts with substrate specificity.

The Journal of biological chemistry 20080208

Specific recognition of Rac2 and Cdc42 by DOCK2 and DOCK9 guanine nucleotide exchange factors.

The Journal of biological chemistry 20080208

3D reconstruction of mammalian septin filaments.

Journal of molecular biology 20080208

The thermodynamics of 3'-terminal pyrene and guanosine for the design of isoenergetic 2'-O-methyl-RNA-LNA chimeric oligonucleotide probes of RNA structure.

Biochemistry 20080205

Exploring specificity of glycosyltransferases: synthesis of new sugar nucleotide related molecules as putative donor substrates.

Carbohydrate research 20080204

Sub-plasmalemmal [Ca2+]i upstroke in myocytes of the guinea-pig small intestine evoked by muscarinic stimulation: IP3R-mediated Ca2+ release induced by voltage-gated Ca2+ entry.

Cell calcium 20080201

Role of ionization of the phosphate cosubstrate on phosphorolysis by purine nucleoside phosphorylase (PNP) of bacterial (E. coli) and mammalian (human) origin.

European biophysics journal : EBJ 20080201

Coupling of the guanosine glycosidic bond conformation and the ribonucleotide cleavage reaction: implications for barnase catalysis.

Proteins 20080201

Mechanism of guanosine-induced neuroprotection in rat hippocampal slices submitted to oxygen-glucose deprivation.

Neurochemistry international 20080201

Dose-related differences in the regional pattern of cannabinoid receptor adaptation and in vivo tolerance development to delta9-tetrahydrocannabinol.

The Journal of pharmacology and experimental therapeutics 20080201

Hydroxyurea nitrosylates and activates soluble guanylyl cyclase in human erythroid cells.

Blood 20080201

Memantine agonist action at dopamine D2High receptors.

Synapse (New York, N.Y.) 20080201

Dopamine partial agonist actions of the glutamate receptor agonists LY 354,740 and LY 379,268.

Synapse (New York, N.Y.) 20080201

Activities of mixed NOP and mu-opioid receptor ligands.

British journal of pharmacology 20080201

Synthesis and pharmacological characterization of a novel, highly potent, peptidomimetic delta-opioid radioantagonist, [3H]Tyr-Tic-(2S,3R)-beta-MePhe-Phe-OH.

Neuropeptides 20080201

Synthesis and anti-HIV activity of 2'-fluorine modified nucleoside phosphonates: analogs of GS-9148.

Bioorganic & medicinal chemistry letters 20080201

cGMP-binding prepares PKG for substrate binding by disclosing the C-terminal domain.

Journal of molecular biology 20080201

A-to-I editing sites are a genomically encoded G: implications for the evolutionary significance and identification of novel editing sites.

RNA (New York, N.Y.) 20080201

In situ evaluation of heavy metal-DNA interactions using an electrochemical DNA biosensor.

Bioelectrochemistry (Amsterdam, Netherlands) 20080201

Synthesis and anti-HIV activity of GS-9148 (2'-Fd4AP), a novel nucleoside phosphonate HIV reverse transcriptase inhibitor.

Bioorganic & medicinal chemistry letters 20080201

Melatonin receptors in brain areas and ocular tissues of the teleost Tinca tinca: characterization and effect of temperature.

General and comparative endocrinology 20080201

The bacterial stringent response, conserved in chloroplasts, controls plant fertilization.

Plant & cell physiology 20080201

pyr RNA binding to the Bacillus caldolyticus PyrR attenuation protein - characterization and regulation by uridine and guanosine nucleotides.

The FEBS journal 20080201

Formation of gutingimycin: analytical investigation of trioxacarcin A-mediated alkylation of dsDNA.

Analytical and bioanalytical chemistry 20080201

Determination of new types of DNA lesions in human sperm.

Zygote (Cambridge, England) 20080201

Clinical application of CpG-, non-CpG-, and antisense oligodeoxynucleotides as immunomodulators.

Current opinion in molecular therapeutics 20080201

Adenylyl cyclase-cyclicAMP signaling in mood disorders: role of the crucial phosphorylating enzyme protein kinase A.

Neuropsychiatric disease and treatment 20080201

Tunable thermoassociation of binary guanosine gels.

The journal of physical chemistry. B 20080131

Neuroprotective effects of guanosine on stroke models in vitro and in vivo.

Neuroscience letters 20080131

Pertussis toxin induces parallel loss of neuropeptide Y Y1 receptor dimers and Gi alpha subunit function in CHO cells.

European journal of pharmacology 20080128

Influence of soluble guanylate cyclase inhibition on inflammation and motility disturbances in DSS-induced colitis.

European journal of pharmacology 20080128

Structural requirements for the activation of Escherichia coli CTP synthase by the allosteric effector GTP are stringent, but requirements for inhibition are lax.

The Journal of biological chemistry 20080125

DNA-protein cross-links between guanine and lysine depend on the mechanism of oxidation for formation of C5 vs C8 guanosine adducts.

Journal of the American Chemical Society 20080116

Oxidative stress in neurodegeneration in dentatorubral-pallidoluysian atrophy.

Journal of the neurological sciences 20080115

A fast synthetic route to GDP-sugars modified at the nucleobase.

Chemical communications (Cambridge, England) 20080114

Profile of glutamate uptake and cellular viability in hippocampal slices exposed to oxygen and glucose deprivation: developmental aspects and protection by guanosine.

Brain research 20080110

Long-term potentiation selectively expressed by NMDA receptors at hippocampal mossy fiber synapses.

Neuron 20080110

Dopamine and corticotropin-releasing factor synergistically alter basolateral amygdala-to-medial prefrontal cortex synaptic transmission: functional switch after chronic cocaine administration.

The Journal of neuroscience : the official journal of the Society for Neuroscience 20080109

Regulation of platelet dense granule secretion by the Ral GTPase-exocyst pathway.

The Journal of biological chemistry 20080104

Pyrene-modified guanosine as fluorescent probe for DNA modulated by charge transfer.

Bioorganic & medicinal chemistry 20080101

Quinolinic acid-induced seizures stimulate glutamate uptake into synaptic vesicles from rat brain: effects prevented by guanine-based purines.

Neurochemical research 20080101

Noladin ether, a putative endocannabinoid, inhibits mu-opioid receptor activation via CB2 cannabinoid receptors.

Neurochemistry international 20080101

Nitric oxide-mediated anxiolytic-like and antidepressant-like effects in animal models of anxiety and depression.

Pharmacology, biochemistry, and behavior 20080101

Manipulation of fatty acid amide hydrolase functional activity alters sensitivity and dependence to ethanol.

Journal of neurochemistry 20080101

Regulation of A(2A) adenosine receptor expression and functioning following permanent focal ischemia in rat brain.

Journal of neurochemistry 20080101

Highly stable giant supramolecular vesicles composed of 2D hydrogen-bonded sheet structures of guanosine derivatives.

Angewandte Chemie (International ed. in English) 20080101

Self-assembly of N2-modified guanosine derivatives: formation of discrete G-octamers.

Chemistry (Weinheim an der Bergstrasse, Germany) 20080101

GTP-independent rapid and slow endocytosis at a central synapse.

Nature neuroscience 20080101

Identification and functional analysis of novel (p)ppGpp synthetase genes in Bacillus subtilis.

Molecular microbiology 20080101

RNAi for treating hepatitis B viral infection.

Pharmaceutical research 20080101

Synergistic actions of diacylglycerol and inositol 1,4,5 trisphosphate for Ca2+-dependent inactivation of TRPC7 channel.

Acta pharmacologica Sinica 20080101

Kinetic pathway of pyrophosphorolysis by a retrotransposon reverse transcriptase.

PloS one 20080101

Codon usage suggests that translational selection has a major impact on protein expression in trypanosomatids.

BMC genomics 20080101

Biochemical characterization of transporter associated with antigen processing (TAP)-like (ABCB9) expressed in insect cells.

Biological & pharmaceutical bulletin 20080101

Expression of membrane progesterone receptors on human T lymphocytes and Jurkat cells and activation of G-proteins by progesterone.

The Journal of endocrinology 20080101

Structure of the yeast tRNA m7G methylation complex.

Structure (London, England : 1993) 20080101

Visible light modulates the expression of cancer-retina antigens.

Molecular cancer research : MCR 20080101

Cyclic tetranuclear half-sandwich ruthenium(II) complexes with 4,7-phenanthroline and hydroxo bridges: crystal structure, solution behaviour and binding to nucleosides.

Journal of inorganic biochemistry 20080101

Substrate specificity and molecular modelling of the feline herpesvirus-1 thymidine kinase.

Archives of virology 20080101

Inhibition of hyaluronan export reduces collagen degradation in interleukin-1 treated cartilage.

Arthritis research & therapy 20080101

Estrogen and progesterone modulate [35S]GTPgammaS binding to nociceptin receptors.

Neuroendocrinology 20080101

Role of vasopressin in the treatment of anaphylactic shock in a child undergoing surgery for congenital heart disease: a case report.

Journal of medical case reports 20080101

The extracytoplasmic stress factor, sigmaE, is required to maintain cell envelope integrity in Escherichia coli.

PloS one 20080101

Visual field defect as a presenting sign for hemorrhagic stroke caused by sildenafil.

Indian journal of ophthalmology 20080101

Co-expression and promoter content analyses assign a role in biotic and abiotic stress responses to plant natriuretic peptides.

BMC plant biology 20080101

RNAi and RNAa--the yin and yang of RNAome.

Bioinformation 20080101

G-rich oligonucleotides alter cell cycle progression and induce apoptosis specifically in OE19 esophageal tumor cells.

Oligonucleotides 20080101

Cyclic GMP in the pig vitreous and retina after experimental retinal detachment.

Molecular vision 20080101

Radiation cataracts: mechanisms involved in their long delayed occurrence but then rapid progression.

Molecular vision 20080101

B12-retro-riboswitches: guanosyl-induced constitutional switching of B12 coenzymes.

Chemistry (Weinheim an der Bergstrasse, Germany) 20080101

Expression of interferon-stimulated gene 20 in vascular endothelial cells.

Microbiology and immunology 20080101

Charge environments around phosphorylation sites in proteins.

BMC structural biology 20080101

Vesicular trafficking: molecular tools and targets.

Methods in molecular biology (Clifton, N.J.) 20080101

Identification and characterization of interacting partners of Rab GTPases by yeast two-hybrid analyses.

Methods in molecular biology (Clifton, N.J.) 20080101

Displacement of protein-bound aptamers with small molecules screened by fluorescence polarization.

Nature protocols 20080101

Evidence for the intense exchange of MazG in marine cyanophages by horizontal gene transfer.

PloS one 20080101

Ribavirin considerations in treatment optimization.

Antiviral therapy 20080101

New advances in anti-HSV chemotherapy.

Current medicinal chemistry 20080101

Excessive islet NO generation in type 2 diabetic GK rats coincides with abnormal hormone secretion and is counteracted by GLP-1.

PloS one 20080101

Dynamics of oxidative damage at early stages of estrogen-dependant carcinogenesis.

Advances in experimental medicine and biology 20080101

High-throughput synthesis of HepDirect prodrugs of nucleoside monophosphates.

Journal of combinatorial chemistry 20080101

Subcellular localization and RNA interference of an RNA methyltransferase gene from silkworm, Bombyx mori.

Comparative and functional genomics 20080101

Exogenous nitric oxide requires an endothelial glycocalyx to prevent postischemic coronary vascular leak in guinea pig hearts.

Critical care (London, England) 20080101

Adaptation and mal-adaptation to ambient hypoxia; Andean, Ethiopian and Himalayan patterns.

PloS one 20080101

Genome-based construction of the metabolic pathways of Orientia tsutsugamushi and comparative analysis within the Rickettsiales order.

Comparative and functional genomics 20080101

[The role of ribavirin in the treatment of chronic hepatitis C].

Przeglad epidemiologiczny 20080101

Identification of differentially expressed proteins in spontaneous thymic lymphomas from knockout mice with deletion of p53.

Proteome science 20080101

IRES-mediated translation of utrophin A is enhanced by glucocorticoid treatment in skeletal muscle cells.

PloS one 20080101

The neuropeptide Y (NPY) Y2 receptors are largely dimeric in the kidney, but monomeric in the forebrain.

Journal of receptor and signal transduction research 20080101

Low response to pegylated interferon plus ribavirin in HIV-infected patients with chronic hepatitis C treated with abacavir.

Antiviral therapy 20080101

Automated discovery and phylogenetic analysis of new toxin-antitoxin systems.

BMC microbiology 20080101

[Study on processing for Rhizoma Pinelliae Praeparatum by comprehensive evaluation of multiple mark].

Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials 20080101

Immortalization of human melanocytes does not alter the de novo properties of nitric oxide to induce cell detachment from extracellular matrix components via cGMP.

In vitro cellular & developmental biology. Animal 20080101

IMP dehydrogenase basal activity in MOLT-4 human leukaemia cells is altered by mycophenolic acid and 6-thioguanosine.

Scandinavian journal of clinical and laboratory investigation 20080101

Transcriptional activity and distribution of splicing machinery elements during Hyacinthus orientalis pollen tube growth.

Protoplasma 20080101

Global regulation of nucleotide biosynthetic genes by c-Myc.

PloS one 20080101

Comparison of human B cell activation by TLR7 and TLR9 agonists.

BMC immunology 20080101

Remodeling of the Streptococcus agalactiae transcriptome in response to growth temperature.

PloS one 20080101

Establishment of rat embryonic stem cells and making of chimera rats.

PloS one 20080101

Evolutionary patterns in the sequence and structure of transfer RNA: a window into early translation and the genetic code.

PloS one 20080101

DnaC inactivation in Escherichia coli K-12 induces the SOS response and expression of nucleotide biosynthesis genes.

PloS one 20080101

Inhibition of the magnesium-sensitive TRPM7-like channel in cardiac myocytes by nonhydrolysable GTP analogs: involvement of phosphoinositide metabolism.

Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 20080101

Chronic cigarette smoke causes oxidative damage and apoptosis to retinal pigmented epithelial cells in mice.

PloS one 20080101

Computational identification of four spliceosomal snRNAs from the deep-branching eukaryote Giardia intestinalis.

PloS one 20080101

Focal Adhesion Kinase contributes to insulin-induced actin reorganization into a mesh harboring Glucose transporter-4 in insulin resistant skeletal muscle cells.

BMC cell biology 20080101

2'-Methylseleno modified oligoribonucleotides synthesized for X-ray crystallography.

Nucleic acids symposium series (2004) 20080101

Synthesis and study of 9-deazaguanosine derivatives as potential inhibitors of RNA virus replication.

Nucleic acids symposium series (2004) 20080101

ppGpp analogues as antibacterial compounds.

Nucleic acids symposium series (2004) 20080101

Long-term platinum retention after treatment with cisplatin and oxaliplatin.

BMC clinical pharmacology 20080101

Impact of viral replication inhibition by entecavir on peripheral T lymphocyte subpopulations in chronic hepatitis B patients.

BMC infectious diseases 20080101

Photodynamic therapy and the development of metal-based photosensitisers.

Metal-based drugs 20080101

Pioglitazone retrieves hepatic antioxidant DNA repair in a mice model of high fat diet.

BMC molecular biology 20080101

The small GTPase RhoH is an atypical regulator of haematopoietic cells.

Cell communication and signaling : CCS 20080101

Bench-to-bedside review: adenosine receptors--promising targets in acute lung injury?

Critical care (London, England) 20080101

The crystal structure of the catalytic domain of a eukaryotic guanylate cyclase.

BMC structural biology 20080101

RNomics and Modomics in the halophilic archaea Haloferax volcanii: identification of RNA modification genes.

BMC genomics 20080101

Distinct expression of synaptic NR2A and NR2B in the central nervous system and impaired morphine tolerance and physical dependence in mice deficient in postsynaptic density-93 protein.

Molecular pain 20080101

Ectopic expression of a truncated CD40L protein from synthetic post-transcriptionally capped RNA in dendritic cells induces high levels of IL-12 secretion.

BMC molecular biology 20080101

Blood oxidative stress markers in non-alcoholic steatohepatitis and how it correlates with diet.

Scandinavian journal of gastroenterology 20080101

Did RNA editing in plant organellar genomes originate under natural selection or through genetic drift?

Biology direct 20080101

Dimers of the neuropeptide Y (NPY) Y2 receptor show asymmetry in agonist affinity and association with G proteins.

Journal of receptor and signal transduction research 20080101

Enhanced A3 adenosine receptor selectivity of multivalent nucleoside-dendrimer conjugates.

Journal of nanobiotechnology 20080101

The prince and the pauper. A tale of anticancer targeted agents.

Molecular cancer 20080101

The role of herpes simplex virus-1 thymidine kinase alanine 168 in substrate specificity.

The open biochemistry journal 20080101

Oxidative stress as a common mediator for apoptosis induced-cardiac damage in diabetic rats.

The open cardiovascular medicine journal 20080101

Association between inflammatory mediators and response to inhaled nitric oxide in a model of endotoxin-induced lung injury.

Critical care (London, England) 20080101

Abnormal energy regulation in early life: childhood gene expression may predict subsequent chronic mountain sickness.

BMC pediatrics 20080101

Comparing methods of detection and quantitation of RNA editing of rat glycine receptor alpha3.

International journal of biological sciences 20080101

Redox mechanisms in hepatic chronic wound healing and fibrogenesis.

Fibrogenesis & tissue repair 20080101

Diets high in selenium and isoflavones decrease androgen-regulated gene expression in healthy rat dorsolateral prostate.

Reproductive biology and endocrinology : RB&E 20080101

Absolute quantification of the budding yeast transcriptome by means of competitive PCR between genomic and complementary DNAs.

BMC genomics 20080101

Properties and distribution of pure GA-sequences of mammalian genomes.

PloS one 20080101

An internal ribosome entry site element directs the synthesis of the 80 kDa isoforms of protein 4.1R.

BMC biology 20080101

Pleiotropic effects of a rel mutation on stress survival of Rhizobium etli CNPAF512.

BMC microbiology 20080101

Flexible modulation of agonist efficacy at the human A3 adenosine receptor by the imidazoquinoline allosteric enhancer LUF6000.

BMC pharmacology 20080101

Integrase and integration: biochemical activities of HIV-1 integrase.

Retrovirology 20080101

Isocyanates induces DNA damage, apoptosis, oxidative stress, and inflammation in cultured human lymphocytes.

Journal of biochemical and molecular toxicology 20080101

Light-induced translocation of cyclic-GMP phosphodiesterase on rod disc membranes in rat retina.

Molecular vision 20080101

Novel therapies for cyclic GMP control of vascular smooth muscle growth.

American journal of therapeutics 20080101

The effect of preservation solutions UW and EC on purine concentration in rat kidney.

Annales Academiae Medicae Stetinensis 20080101

Rickettsia phylogenomics: unwinding the intricacies of obligate intracellular life.

PloS one 20080101

Repeated administration of the dopaminergic agonist apomorphine: development of apomorphine aggressiveness and changes in the interaction between dopamine D(2) receptors and G-proteins.

Pharmacological reports : PR 20080101

The human vaginal bacterial biota and bacterial vaginosis.

Interdisciplinary perspectives on infectious diseases 20080101

Emergency treatment of a snake bite: Pearls from literature.

Journal of emergencies, trauma, and shock 20080101

cGMP in ozone and NO dependent responses.

Plant signaling & behavior 20080101

Advances in antisense oligonucleotide development for target identification, validation, and as novel therapeutics.

Gene regulation and systems biology 20080101

Management of erythema nodosum leprosum by mycophenolate mofetil.

Indian journal of dermatology 20080101

The imaging probe development center and the production of molecular imaging probes.

Current chemical genomics 20080101

Psychological factors in asthma.

Allergy, asthma, and clinical immunology : official journal of the Canadian Society of Allergy and Clinical Immunology 20080101

Recurrent Respiratory Papillomatosis (RRP)-Juvenile Onset.

Clinical medicine. Oncology 20080101

Herpes simplex Virus Esophagitis in an Immunocompetent Patient with Ebstein-Barr Virus Infection.

Case reports in gastroenterology 20080101

Synthesis of 5'-amino-5'-deoxyguanosine-5'-N-phosphoramidate and its enzymatic incorporation at the 5'-termini of RNA molecules.

Chemical communications (Cambridge, England) 20071221

Specific interaction between EF-G and RRF and its implication for GTP-dependent ribosome splitting into subunits.

Journal of molecular biology 20071214

Calcium-activated (p)ppGpp synthetase in chloroplasts of land plants.

The Journal of biological chemistry 20071207

A short and efficient synthesis of the tRNA nucleosides PreQ0 and archaeosine.

Organic & biomolecular chemistry 20071207

Synthesis and DNA incorporation of an ethynyl-bridged cytosine C-nucleoside as guanosine surrogate.

Organic letters 20071206

Short-term effects of 3,4-methylen-dioxy-metamphetamine (MDMA) on 5-HT(1A) receptors in the rat hippocampus.

Neurochemistry international 20071201

The basal levels of 8-oxoG and other oxidative modifications in intact mitochondrial DNA are low even in repair-deficient (Ogg1(-/-)/Csb(-/-)) mice.

Mutation research 20071201

Narrow-band UVB induces more carcinogenic skin tumors than broad-band UVB through the formation of cyclobutane pyrimidine dimer.

The Journal of investigative dermatology 20071201

An 80-amino acid deletion in the third intracellular loop of a naturally occurring human histamine H3 isoform confers pharmacological differences and constitutive activity.

The Journal of pharmacology and experimental therapeutics 20071201

The orphan receptor GPR55 is a novel cannabinoid receptor.

British journal of pharmacology 20071201

Proposal of a guanine-based purinergic system in the mammalian central nervous system.

Pharmacology & therapeutics 20071201

Regulatory interaction of the Galpha protein with phospholipase A2 in the plasma membrane of Eschscholzia californica.

The Plant journal : for cell and molecular biology 20071201

Nonenzymatic glycation of guanosine 5'-triphosphate by glyceraldehyde: an in vitro study of AGE formation.

Bioorganic chemistry 20071201

CB1 knockout mice display impaired functionality of 5-HT1A and 5-HT2A/C receptors.

Journal of neurochemistry 20071201

Endothelium-targeted transgenic GTP-cyclohydrolase I overexpression inhibits neointima formation in mouse carotid artery.

Clinical and experimental pharmacology & physiology 20071201

Base excision repair processing of abasic site/single-strand break lesions within clustered damage sites associated with XRCC1 deficiency.

Nucleic acids research 20071201

C-terminal truncated cannabinoid receptor 1 coexpressed with G protein trimer in Sf9 cells exists in a precoupled state and shows constitutive activity.

The FEBS journal 20071201

Endogenous heptapeptide Met-enkephalin-Gly-Tyr binds differentially to duplicate delta opioid receptors from zebrafish.

Peptides 20071201

In vitro screening of psychoactive drugs by [(35)S]GTPgammaS binding in rat brain membranes.

Biological & pharmaceutical bulletin 20071201

Role of calmodulin and myosin light chain kinase in the activation of carbachol-activated cationic current in murine ileal myocytes.

Canadian journal of physiology and pharmacology 20071201

Changes of nitric oxide, carbon monoxide and oxidative stress in term infants at birth.

Free radical research 20071201

Medicinal applications of fullerenes.

International journal of nanomedicine 20071201

Role of nelarabine in the treatment of T-cell acute lymphoblastic leukemia and T-cell lymphoblastic lymphoma.

Therapeutics and clinical risk management 20071201

Human 5-HT(4) and 5-HT(7) receptor splice variants: are they important?

Current neuropharmacology 20071201

Nucleic acid aptamers for targeting of shRNA-based cancer therapeutics.

Biologics : targets & therapy 20071201

Secretory protein mRNA finds another way out.

PLoS biology 20071201

Allosteric small molecules unveil a role of an extracellular E2/transmembrane helix 7 junction for G protein-coupled receptor activation.

The Journal of biological chemistry 20071130

A charge reversal differentiates (p)ppGpp synthesis by monofunctional and bifunctional Rel proteins.

The Journal of biological chemistry 20071130

Induction of megakaryocytic differentiation in chronic myelogenous leukemia cell K562 by 3-hydrogenkwadaphnin.

Journal of biochemistry and molecular biology 20071130

Tickling-induced 50-kHz ultrasonic vocalization is individually stable and predicts behaviour in tests of anxiety and depression in rats.

Behavioural brain research 20071122

Dysregulation of the endogenous cannabinoid system in adult rats prenatally treated with the cannabinoid agonist WIN 55,212-2.

European journal of pharmacology 20071114

[Attention-getting sexually transmitted diseases: Hepatitis B].

Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine 20071110

A bifunctional bacterial protein links GDI displacement to Rab1 activation.

Science (New York, N.Y.) 20071109

Rheb activates mTOR by antagonizing its endogenous inhibitor, FKBP38.

Science (New York, N.Y.) 20071109

Inosine-containing dsRNA binds a stress-granule-like complex and downregulates gene expression in trans.

Molecular cell 20071109

Time-resolved resonance Raman investigation of the 2-fluorenylnitrenium ion reactions with C8 guanosine derivatives.

The journal of physical chemistry. B 20071108

Linkage between substrate recognition and catalysis during cleavage of sarcin/ricin loop RNA by restrictocin.

Biochemistry 20071106

Design of an optimal allele-specific oligonucleotide probe for the efficient discrimination of a thermodynamically stable (G x T) mismatch.

Analytica chimica acta 20071105

Overexpression of a Zn2+-sensitive soluble exopolyphosphatase from Trypanosoma cruzi depletes polyphosphate and affects osmoregulation.

The Journal of biological chemistry 20071102

Selective guanosine binding and cytotoxicity of a benzimidazole derived dinickel complex.

Journal of inorganic biochemistry 20071101

PSNCBAM-1, a novel allosteric antagonist at cannabinoid CB1 receptors with hypophagic effects in rats.

British journal of pharmacology 20071101

Significance of cannabinoid CB1 receptors in improgan antinociception.

The journal of pain : official journal of the American Pain Society 20071101

Characterization of guanine and guanosine transport in primary cultured rat cortical astrocytes and neurons.

Glia 20071101

Cyclic GMP and protein kinase-G in myocardial ischaemia-reperfusion: opportunities and obstacles for survival signaling.

British journal of pharmacology 20071101

C-type natriuretic peptide enhances amylase release through NPR-C receptors in the exocrine pancreas.

American journal of physiology. Gastrointestinal and liver physiology 20071101

The novel endocannabinoid receptor GPR55 is activated by atypical cannabinoids but does not mediate their vasodilator effects.

British journal of pharmacology 20071101

Kinetics and mechanism of the substitution reactions of [PtCl(bpma)]+, [PtCl(gly-met-S,N,N)] and their aqua analogues with L-methionine, glutathione and 5'-GMP.

Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry 20071101

A select set of opioid ligands induce up-regulation by promoting the maturation and stability of the rat kappa-opioid receptor in human embryonic kidney 293 cells.

The Journal of pharmacology and experimental therapeutics 20071101

Extracellular renal guanosine cyclic 3'5'-monophosphate modulates nitric oxide and pressure-induced natriuresis.

Hypertension (Dallas, Tex. : 1979) 20071101

Developmental changes in agonist-induced retrograde signaling at parallel fiber-Purkinje cell synapses: role of calcium-induced calcium release.

Journal of neurophysiology 20071101

Effects of receptor density on Nociceptin/OrphaninFQ peptide receptor desensitisation: studies using the ecdysone inducible expression system.

Naunyn-Schmiedeberg's archives of pharmacology 20071101

Protein S-guanylation by the biological signal 8-nitroguanosine 3',5'-cyclic monophosphate.

Nature chemical biology 20071101

Ammonia elimination from protonated nucleobases and related synthetic substrates.

Journal of the American Society for Mass Spectrometry 20071101

Examination of the mechanism and energetic contribution of leaving group activation in the purine-specific nucleoside hydrolase from Trypanosoma vivax.

Biochimica et biophysica acta 20071101

G protein activation by uncaging of GTP-gamma-S in the leech giant glial cell.

The Journal of experimental biology 20071101

Effects of azimilide on the muscarinic acetylcholine receptor-operated K+ current and experimental atrial fibrillation in guinea-pig hearts.

Journal of pharmacological sciences 20071101

Effects of ginseng total saponins on pacemaker currents of interstitial cells of Cajal from the small intestine of mice.

Biological & pharmaceutical bulletin 20071101

tRNASer acceptor stem: conformation and hydration of a microhelix in a crystal structure at 1.8 A resolution.

Acta crystallographica. Section D, Biological crystallography 20071101

PF1270A, B and C, novel histamine H3 receptor ligands produced by Penicillium waksmanii PF1270.

The Journal of antibiotics 20071101

Effect of hydrogen peroxide on VIP-induced relaxation of the cat lower esophageal sphincter.

Archives of pharmacal research 20071101

Activation of protein kinase B/Akt and endothelial nitric oxide synthase mediates agmatine-induced endothelium-dependent relaxation.

European journal of pharmacology 20071031

Anopheles gambiae purine nucleoside phosphorylase: catalysis, structure, and inhibition.

Biochemistry 20071030

Reactions of fac-[Re(CO)3(H2O)3]+ with nucleoside diphosphates and thiamine diphosphate in aqueous solution investigated by multinuclear NMR spectroscopy.

Inorganic chemistry 20071029

Changes to the HIV long terminal repeat and to HIV integrase differentially impact HIV integrase assembly, activity, and the binding of strand transfer inhibitors.

The Journal of biological chemistry 20071026

Factors affecting guanine nucleotide binding to rat AMPA receptors.

Brain research 20071026

Chronic morphine treatment up-regulates mu opioid receptor binding in cells lacking filamin A.

Brain research 20071026

Efficient syntheses of 5'-deoxy-5'-fluoroguanosine and -inosine.

The Journal of organic chemistry 20071026

Spiroiminodihydantoin as an oxo-atom transfer product of 8-oxo-2'-deoxyguanosine oxidation by chromium(V).

Organic letters 20071025

Crystal structure of the radical SAM enzyme catalyzing tricyclic modified base formation in tRNA.

Journal of molecular biology 20071005

Urinary analysis of 8-oxoguanine, 8-oxoguanosine, fapy-guanine and 8-oxo-2'-deoxyguanosine by high-performance liquid chromatography-electrospray tandem mass spectrometry as a measure of oxidative stress.

Journal of chromatography. A 20071005

Muscarinic activity modulated by C-type natriuretic peptide in gastric smooth muscles of guinea-pig stomach.

Regulatory peptides 20071004

Effect of early rearing conditions on alcohol drinking and 5-HT1A receptor function in C57BL/6J mice.

The international journal of neuropsychopharmacology 20071001

Electroconvulsive shock treatment differentially modulates cortical and subcortical endocannabinoid activity.

Journal of neurochemistry 20071001

Self-organization of guanosine 5'-monophosphate on mica.

Colloids and surfaces. B, Biointerfaces 20071001

Low dose combination of morphine and delta9-tetrahydrocannabinol circumvents antinociceptive tolerance and apparent desensitization of receptors.

European journal of pharmacology 20071001

[N-allyl-Dmt1]-endomorphins are micro-opioid receptor antagonists lacking inverse agonist properties.

The Journal of pharmacology and experimental therapeutics 20071001

Rho guanosine 5'-triphosphatases differentially regulate insulin-like growth factor I (IGF-I) receptor-dependent and -independent actions of IGF-II on human trophoblast migration.

Endocrinology 20071001

CAT-2 amplifies the agonist-evoked force of airway smooth muscle by enhancing spermine-mediated phosphatidylinositol-(4)-phosphate-5-kinase-gamma activity.

American journal of physiology. Lung cellular and molecular physiology 20071001

Pharmacokinetics and pharmacodynamics of seven opioids in P-glycoprotein-competent mice: assessment of unbound brain EC50,u and correlation of in vitro, preclinical, and clinical data.

The Journal of pharmacology and experimental therapeutics 20071001

(-)-(1R,2R)-3-(3-dimethylamino-1-ethyl-2-methyl-propyl)-phenol hydrochloride (tapentadol HCl): a novel mu-opioid receptor agonist/norepinephrine reuptake inhibitor with broad-spectrum analgesic properties.

The Journal of pharmacology and experimental therapeutics 20071001

Action of Pasteurella multocida toxin on Galpha(q) is persistent and independent of interaction with G-protein-coupled receptors.

Cellular signalling 20071001

Optimizing nitric oxide production by time dependent L-arginine administration in isolated human corpus cavernosum.

The Journal of urology 20071001

Structure-activity relationship studies of carboxamido-biaryl ethers as opioid receptor antagonists (OpRAs). Part 1.

Bioorganic & medicinal chemistry letters 20071001

Synthesis and application of 2'-fluoro-substituted cap analogs.

Bioorganic & medicinal chemistry letters 20071001

Inverse agonist exposure enhances ligand binding and G protein activation of the human MT1 melatonin receptor, but leads to receptor down-regulation.

Journal of pineal research 20071001

Equine recurrent airway obstruction does not alter airway muscarinic acetylcholine receptor expression and subtype distribution.

Journal of veterinary pharmacology and therapeutics 20071001

TLR agonists induce the differentiation of human bone marrow CD34+ progenitors into CD11c+ CD80/86+ DC capable of inducing a Th1-type response.

European journal of immunology 20071001

Spiroiminodihydantoin nucleoside formation from 2'-deoxyguanosine oxidation by [(18)O-labeled] singlet molecular oxygen in aqueous solution.

Journal of mass spectrometry : JMS 20071001

Segregation of odor identity and intensity during odor discrimination in Drosophila mushroom body.

PLoS biology 20071001

Saving the ischemic penumbra: potential role for statins and phosphodiesterase inhibitors.

Current vascular pharmacology 20071001

Gene regulation by mechanotransduction in fibroblasts.

Applied physiology, nutrition, and metabolism = Physiologie appliquee, nutrition et metabolisme 20071001

Gingival crevicular fluid levels of neopterin in healthy subjects and in patients with different periodontal diseases.

Journal of periodontology 20071001

Nebivolol in the treatment of chronic heart failure.

Vascular health and risk management 20071001

The involvement of nitric oxide in ultraviolet-B-inhibited pollen germination and tube growth of Paulownia tomentosa in vitro.

Physiologia plantarum 20071001

N-Glycosylation of the human kappa opioid receptor enhances its stability but slows its trafficking along the biosynthesis pathway.

Biochemistry 20070925

Yeast mitochondrial initiator tRNA is methylated at guanosine 37 by the Trm5-encoded tRNA (guanine-N1-)-methyltransferase.

The Journal of biological chemistry 20070921

Structural and functional analysis of methylation and 5'-RNA sequence requirements of short capped RNAs by the methyltransferase domain of dengue virus NS5.

Journal of molecular biology 20070921

Pyrazolo[3,4-d]pyrimidine ribonucleosides related to 2-aminoadenosine and isoguanosine: synthesis, deamination and tautomerism.

Organic & biomolecular chemistry 20070921

Inhibition of Mycobacterium tuberculosis, Mycobacterium bovis, and Mycobacterium avium by novel dideoxy nucleosides.

Journal of medicinal chemistry 20070920

Gas-phase formation of radical cations of monomers and dimers of guanosine by collision-induced dissociation of Cu(II)-guanosine complexes.

The journal of physical chemistry. B 20070920

Allosteric effects of antagonists on signalling by the chemokine receptor CCR5.

Biochemical pharmacology 20070915

Fast simultaneous determination of 14 nucleosides and nucleobases in cultured Cordyceps using ultra-performance liquid chromatography.

Talanta 20070915

Live cell monitoring of mu-opioid receptor-mediated G-protein activation reveals strong biological activity of close morphine biosynthetic precursors.

The Journal of biological chemistry 20070914

Novel diastereomeric opioid tetrapeptides exhibit differing pharmacological activity profiles.

Brain research bulletin 20070914

Adenosine deaminase 1 and concentrative nucleoside transporters 2 and 3 regulate adenosine on the apical surface of human airway epithelia: implications for inflammatory lung diseases.

Biochemistry 20070911

Translocation of activated heterotrimeric G protein Galpha(o) to ganglioside-enriched detergent-resistant membrane rafts in developing cerebellum.

The Journal of biological chemistry 20070907

Crystallographic and mass spectrometric characterisation of eIF4E with N7-alkylated cap derivatives.

Journal of molecular biology 20070907

Cysteine redox sensor in PKGIa enables oxidant-induced activation.

Science (New York, N.Y.) 20070907

Regulation of serotonin-1A receptor function in inducible brain-derived neurotrophic factor knockout mice after administration of corticosterone.

Biological psychiatry 20070901

Role of matrix metalloproteinase and tissue inhibitor of MMP in methamphetamine-induced behavioral sensitization and reward: implications for dopamine receptor down-regulation and dopamine release.

Journal of neurochemistry 20070901

Synthesis and anti-HIV activity of (-)-beta-D-(2R,4R)-1,3-dioxolane-2,6-diamino purine (DAPD) (amdoxovir) and (-)-beta-D-(2R,4R)-1,3-dioxolane guanosine (DXG) prodrugs.

Antiviral research 20070901

Preprodynorphin mediates locomotion and D2 dopamine and mu-opioid receptor changes induced by chronic 'binge' cocaine administration.

Journal of neurochemistry 20070901

Localization of the mouse 5-hydroxytryptamine(1A) receptor in lipid microdomains depends on its palmitoylation and is involved in receptor-mediated signaling.

Molecular pharmacology 20070901

2'-O-methyl-modified RNAs act as TLR7 antagonists.

Molecular therapy : the journal of the American Society of Gene Therapy 20070901

DNAzyme-mediated inhibition of Japanese encephalitis virus replication in mouse brain.

Molecular therapy : the journal of the American Society of Gene Therapy 20070901

Assessing biomarkers of oxidative stress: analysis of guanosine and oxidized guanosine nucleotide triphosphates by high performance liquid chromatography with electrochemical detection.

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20070901

Functionalization of the 6,14-bridge of the orvinols. Part 3: preparation and pharmacological evaluation of 18- and 19-hydroxyl substituted orvinols.

Bioorganic & medicinal chemistry letters 20070901

Stimulating and inhibitory effects of the dopamine 'stabilizer' (-)-OSU6162 on dopamine D2 receptor function in vitro.

Journal of neural transmission (Vienna, Austria : 1996) 20070901

The rare earth, scandium, causes antibiotic overproduction in Streptomyces spp.

FEMS microbiology letters 20070901

Mg2+ binding and archaeosine modification stabilize the G15 C48 Levitt base pair in tRNAs.

RNA (New York, N.Y.) 20070901

Protective effect of endothelial nitric oxide synthase against induction of chemically-induced diabetes in mice.

Nitric oxide : biology and chemistry 20070901

Three gene products govern (p)ppGpp production by Streptococcus mutans.

Molecular microbiology 20070901

The effect of varying continuous propofol infusions on plasma cyclic guanosine 3',5'-monophosphate concentrations in anesthetized children.

Anesthesia and analgesia 20070901

Role of nitric oxide pathway in placental dysfunction following fetal bypass.

The Annals of thoracic surgery 20070901

Guanosine acts intracellularly to initiate apoptosis in NB4 cells: A role for nucleoside transport.

Leukemia & lymphoma 20070901

Ameliorating the developmental neurotoxicity of chlorpyrifos: a mechanisms-based approach in PC12 cells.

Environmental health perspectives 20070901

A cyclic-di-GMP receptor required for bacterial exopolysaccharide production.

Molecular microbiology 20070901

Effects of oseltamivir phosphate (Tamiflu) and its metabolite (GS4071) on monoamine neurotransmission in the rat brain.

Biological & pharmaceutical bulletin 20070901

Mitochondria are an essential mediator of nitric oxide/cyclic guanosine 3',5'-monophosphate blocking of glucose depletion induced cytotoxicity in human HepG2 cells.

Molecular cancer research : MCR 20070901

TLR3 and TLR7 are involved in expression of IL-23 subunits while TLR3 but not TLR7 is involved in expression of IFN-beta by Theiler's virus-infected RAW264.7 cells.

Microbes and infection 20070901

A comprehensive genetic characterization of bacterial motility.

PLoS genetics 20070901

[(3)H]Adenine is a suitable radioligand for the labeling of G protein-coupled adenine receptors but shows high affinity to bacterial contaminations in buffer solutions.

Purinergic signalling 20070901

MPP(+)-induced cytotoxicity in neuroblastoma cells: Antagonism and reversal by guanosine.

Purinergic signalling 20070901

Guanosine reduces apoptosis and inflammation associated with restoration of function in rats with acute spinal cord injury.

Purinergic signalling 20070901

A review of antisense therapeutic interventions for molecular biological targets in asthma.

Biologics : targets & therapy 20070901

Intrinsic electrophilic properties of nucleosides: photoelectron spectroscopy of their parent anions.

The Journal of chemical physics 20070828

The RACK1 ortholog Asc1 functions as a G-protein beta subunit coupled to glucose responsiveness in yeast.

The Journal of biological chemistry 20070824

Helix 8 Leu in the CB1 cannabinoid receptor contributes to selective signal transduction mechanisms.

The Journal of biological chemistry 20070824

Metabotropic glutamate 2/3 receptors in the ventral tegmental area and the nucleus accumbens shell are involved in behaviors relating to nicotine dependence.

The Journal of neuroscience : the official journal of the Society for Neuroscience 20070822

Unusual structural features of hydantoin lesions translate into efficient recognition by Escherichia coli Fpg.

Biochemistry 20070821

Proteasome-dependent degradation of guanosine 5'-triphosphate cyclohydrolase I causes tetrahydrobiopterin deficiency in diabetes mellitus.

Circulation 20070821

Transcriptional networking cap-tures the 7SK RNA 5'-gamma-methyltransferase.

Molecular cell 20070817

The brain cytoplasmic RNA BC1 regulates dopamine D2 receptor-mediated transmission in the striatum.

The Journal of neuroscience : the official journal of the Society for Neuroscience 20070815

The mid-IR spectra of 9-ethyl guanine, guanosine, and 2-deoxyguanosine.

The journal of physical chemistry. A 20070809

Exogenous nucleic acids and nucleotides are efficiently hydrolysed and taken up as nucleosides by intestinal explants from suckling piglets.

The British journal of nutrition 20070801

Structural analysis of Cu(II) ligation to the 5'-GMP nucleotide by pulse EPR spectroscopy.

Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry 20070801

Mechanisms responsible for the enhanced antinociceptive effects of micro-opioid receptor agonists in the rostral ventromedial medulla of male rats with persistent inflammatory pain.

The Journal of pharmacology and experimental therapeutics 20070801

Pharmacological characterization of Sch527123, a potent allosteric CXCR1/CXCR2 antagonist.

The Journal of pharmacology and experimental therapeutics 20070801

Structure-function studies of allosteric agonism at M2 muscarinic acetylcholine receptors.

Molecular pharmacology 20070801

Urinary 8-hydroxydeoxyguanosine is elevated in patients with nephrolithiasis.

Urological research 20070801

Genome-wide transcriptome profiling of region-specific vulnerability to oxidative stress in the hippocampus.

Genomics 20070801

TLR-TLR cross talk in human PBMC resulting in synergistic and antagonistic regulation of type-1 and 2 interferons, IL-12 and TNF-alpha.

International immunopharmacology 20070801

Region-dependent attenuation of mu opioid receptor-mediated G-protein activation in mouse CNS as a function of morphine tolerance.

British journal of pharmacology 20070801

Action of novel antipsychotics at human dopamine D3 receptors coupled to G protein and ERK1/2 activation.

Neuropharmacology 20070801

In vitro pharmacological characterisation of a novel cyclic nociceptin/orphanin FQ analogue c[Cys(7,10)]N/OFQ(1-13)NH (2).

Naunyn-Schmiedeberg's archives of pharmacology 20070801

Sch35966 is a potent, selective agonist at the peripheral cannabinoid receptor (CB2) in rodents and primates.

British journal of pharmacology 20070801

Ultrafast electronic relaxation in guanosine is promoted by hydrogen bonding with cytidine.

Journal of the American Chemical Society 20070801

Mechanisms underlying agonist efficacy.

Biochemical Society transactions 20070801

Evaluation of nonleukoreduced red blood cell transfusion units collected at delivery from the placenta.

Transfusion 20070801

Guanosine gel for sequence-dependent separation of polymorphic ssDNA.

Electrophoresis 20070801

Intrinsic fluorescence of B and Z forms of poly d(G-m5C).poly d(G-m5C), a synthetic double-stranded DNA: spectra and lifetimes by the maximum entropy method.

Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology 20070801

Co-localization and functional cross-talk between A1 and P2Y1 purine receptors in rat hippocampus.

The European journal of neuroscience 20070801

Nitroimidazole action in Entamoeba histolytica: a central role for thioredoxin reductase.

PLoS biology 20070801

Age-associated oxidative macromolecular damages in rat brain regions: role of glutathione monoester.

The journals of gerontology. Series A, Biological sciences and medical sciences 20070801

1Alpha,25-dihydroxyvitamin D3 modulation of adipocyte reactive oxygen species production.

Obesity (Silver Spring, Md.) 20070801

[Apoptosis induced by base mismatches].

Fukuoka igaku zasshi = Hukuoka acta medica 20070801

[Chemical study of nucleosides on Cordyceps militaris].

Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials 20070801

Qualitative and quantitative analyses of nucleosides and nucleobases in Ganoderma spp. by HPLC-DAD-MS.

Journal of pharmaceutical and biomedical analysis 20070727

Acridone-based inhibitors of inosine 5'-monophosphate dehydrogenase: discovery and SAR leading to the identification of N-(2-(6-(4-ethylpiperazin-1-yl)pyridin-3-yl)propan-2-yl)-2- fluoro-9-oxo-9,10-dihydroacridine-3-carboxamide (BMS-566419).

Journal of medicinal chemistry 20070726

Quantifying hydrogen-bonding strength: the measurement of 2hJNN couplings in self-assembled guanosines by solid-state 15N spin-echo MAS NMR.

Physical chemistry chemical physics : PCCP 20070714

Nucleoside transporter expression and activity is regulated during granulocytic differentiation of NB4 cells in response to all-trans-retinoic acid.

Leukemia research 20070701

Relaxation of the isolated human internal anal sphincter by sildenafil.

The British journal of surgery 20070701

Genome-wide expression profiling in Geobacter sulfurreducens: identification of Fur and RpoS transcription regulatory sites in a relGsu mutant.

Functional & integrative genomics 20070701

Oxidative stress reduces renal dopamine D1 receptor-Gq/11alpha G protein-phospholipase C signaling involving G protein-coupled receptor kinase 2.

American journal of physiology. Renal physiology 20070701

Three distinct muscarinic signalling pathways for cationic channel activation in mouse gut smooth muscle cells.

The Journal of physiology 20070701

Simvastatin suppresses self-renewal of mouse embryonic stem cells by inhibiting RhoA geranylgeranylation.

Stem cells (Dayton, Ohio) 20070701

Thyrotropin activates guanosine 5'-diphosphate/guanosine 5'-triphosphate exchange on the rate-limiting endocytic catalyst, Rab5a, in human thyrocytes in vivo and in vitro.

The Journal of clinical endocrinology and metabolism 20070701

Synthesis and biological activity of new melatonin dimeric derivatives.

Bioorganic & medicinal chemistry 20070701

Synthesis and biological activity of nociceptin/orphanin FQ analogues substituted in position 7 or 11 with Calpha,alpha-dialkylated amino acids.

Bioorganic & medicinal chemistry 20070701

Modulation of a delayed-rectifier K+ current by angiotensin II in rat sympathetic neurons.

Journal of neurophysiology 20070701

Role of the stage-regulated nucleoside transporter TbNT10 in differentiation and adenosine uptake in Trypanosoma brucei.

Molecular and biochemical parasitology 20070701

Guanine derivatives modulate extracellular matrix proteins organization and improve neuron-astrocyte co-culture.

Journal of neuroscience research 20070701

Pentylenetetrazol kindling alters adenine and guanine nucleotide catabolism in rat hippocampal slices and cerebrospinal fluid.

Epilepsy research 20070701

Regulation of T-type calcium channels by Rho-associated kinase.

Nature neuroscience 20070701

Structure of a human telomeric DNA sequence stabilized by 8-bromoguanosine substitutions, as determined by NMR in a K+ solution.

The FEBS journal 20070701

Polyphosphate kinase is involved in stress-induced mprAB-sigE-rel signalling in mycobacteria.

Molecular microbiology 20070701

Functional analysis of the residues C770 and G771 of E. coli 16S rRNA implicated in forming the intersubunit bridge B2c of the ribosome.

Journal of microbiology and biotechnology 20070701

New platinum(II) complexes containing both an O,O'-chelated acetylacetonate ligand and a sulfur ligand in the platinum coordination sphere induce apoptosis in HeLa cervical carcinoma cells.

Biochemical pharmacology 20070630

Macrophage biospecific extraction and high performance liquid chromatography for hypothesis of immunological active components in Cordyceps sinensis.

Journal of pharmaceutical and biomedical analysis 20070628

Electron transfer between guanosine radical and amino acids in aqueous solution. 1. Reduction of guanosine radical by tyrosine.

The journal of physical chemistry. B 20070628

Substrate specificity of Fpg (MutM) and hOGG1, two repair glycosylases.

Journal of the American Chemical Society 20070627

Transcriptomal profiling of the cellular transformation induced by Rho subfamily GTPases.

Oncogene 20070621

Scaffold hopping, synthesis and structure-activity relationships of 5,6-diaryl-pyrazine-2-amide derivatives: a novel series of CB1 receptor antagonists.

Bioorganic & medicinal chemistry 20070615

Genetic selection for a highly functional cysteine-less membrane protein using site saturation mutagenesis.

Analytical biochemistry 20070615

Selective interactions of a few acridinium derivatives with single strand DNA: study of photophysical and DNA binding interactions.

The journal of physical chemistry. B 20070614

Site-selective depurination by a periodate-dependent deoxyribozyme.

Chemical communications (Cambridge, England) 20070614

Metabotropic glutamate receptor/phospholipase C system in female rat heart.

Brain research 20070611

fac-[Re(CO)3(H2O)3]+ nucleoside monophosphate adducts investigated in aqueous solution by multinuclear NMR spectroscopy.

Inorganic chemistry 20070611

Characterization of Rab45/RASEF containing EF-hand domain and a coiled-coil motif as a self-associating GTPase.

Biochemical and biophysical research communications 20070608

Nuclear membrane disassembly and rupture.

Journal of molecular biology 20070608

Useful detection of CD147 (EMMPRIN) for pathological diagnosis of early hepatocellular carcinoma in needle biopsy samples.

World journal of gastroenterology 20070607

X-ray crystal structures reveal two activated states for RhoC.

Biochemistry 20070605

Gene transcription alterations associated with decrease of ethanol intake induced by naltrexone in the brain of Wistar rats.

Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20070601

The capacity to remove 8-oxoG is enhanced in newborn neural stem/progenitor cells and decreases in juvenile mice and upon cell differentiation.

DNA repair 20070601

G protein activation inhibits gating charge movement in rat sympathetic neurons.

American journal of physiology. Cell physiology 20070601

GSK189254, a novel H3 receptor antagonist that binds to histamine H3 receptors in Alzheimer's disease brain and improves cognitive performance in preclinical models.

The Journal of pharmacology and experimental therapeutics 20070601

Pharmacological characterization of the nociceptin/orphanin FQ receptor antagonist SB-612111 [(-)-cis-1-methyl-7-[[4-(2,6-dichlorophenyl)piperidin-1-yl]methyl]-6,7,8,9-tetrahydro-5H-benzocyclohepten-5-ol]: in vitro studies.

The Journal of pharmacology and experimental therapeutics 20070601

Effects of chronic opioid exposure on guinea pig mu opioid receptor in Chinese hamster ovary cells: comparison with human and rat receptor.

Biochemical pharmacology 20070601

Rapid modulation of micro-opioid receptor signaling in primary sensory neurons.

The Journal of pharmacology and experimental therapeutics 20070601

In vitro and in vivo pharmacological characterization of ethyl-4-[trans-4-[((2S)-2-hydroxy-3-[4-hydroxy-3[(methylsulfonyl)amino]-phenoxy]propyl) amino]cyclohexyl]benzoate hydrochloride (SAR150640), a new potent and selective human beta3-adrenoceptor agonist for the treatment of preterm labor.

The Journal of pharmacology and experimental therapeutics 20070601

Identification of a platyhelminth neuropeptide receptor.

International journal for parasitology 20070601

Mutation studies of Ser7.39 and Ser2.60 in the human CB1 cannabinoid receptor: evidence for a serine-induced bend in CB1 transmembrane helix 7.

Molecular pharmacology 20070601

Incorporation of low molecular weight molecules into alpha(2)-macroglobulin by nucleophilic exchange.

Biochemical and biophysical research communications 20070601

Cleavage of an RNA analog by Zn(II) macrocyclic catalysts appended with a methyl or an acridine group.

Journal of inorganic biochemistry 20070601

Optimization of CEC for simultaneous determination of eleven nucleosides and nucleobases in Cordyceps using central composite design.

Electrophoresis 20070601

Homologous desensitization of signalling by the alpha (alpha) isoform of the human thromboxane A2 receptor: a specific role for nitric oxide signalling.

Biochimica et biophysica acta 20070601

Therapeutic issues in HIV/HCV-coinfected patients.

Journal of viral hepatitis 20070601

8-oxo-7,8-dihydroguanosine triphosphate(8-oxoGTP) down-regulates respiratory burst of neutrophils by antagonizing GTP toward Rac, a small GTP binding protein.

Free radical research 20070601

Adrenaline stimulates H2O2 generation in liver via NADPH oxidase.

Free radical research 20070601

Different Ca2+ signalling cascades manifested by mastoparan in the prothoracic glands of the tobacco hornworm, Manduca sexta, and the silkworm, Bombyx mori.

Archives of insect biochemistry and physiology 20070601

Genetic inactivation of RelA/p65 sensitizes adult mouse hepatocytes to TNF-induced apoptosis in vivo and in vitro.

Gastroenterology 20070601

A dispermic chimera with mixed field blood group B and mosaic 46,XY/47,XYY karyotype.

Journal of Korean medical science 20070601

[Comparative study on main economic characters of different populations of Pinellia ternata in China].

Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20070601

Status epilepticus causes a long-lasting redistribution of hippocampal cannabinoid type 1 receptor expression and function in the rat pilocarpine model of acquired epilepsy.

Neuroscience 20070525

Proteinase-activated receptors 1 and 2 in rat olfactory system: layer-specific regulation of multiple signaling pathways in the main olfactory bulb and induction of neurite retraction in olfactory sensory neurons.

Neuroscience 20070525

OGG1 initiates age-dependent CAG trinucleotide expansion in somatic cells.

Nature 20070524

Effects of local anesthetics on opioid inhibition of calcium current in rat dorsal root ganglion neurons.

Neuroscience letters 20070518

Supramolecular polymers based on the quadruplex formation of ditopic guanosine macromonomers in nonaqueous media.

Langmuir : the ACS journal of surfaces and colloids 20070508

Lesion specificity in the base excision repair enzyme hNeil1: modeling and dynamics studies.

Biochemistry 20070508

9-(2-C-Cyano-2-deoxy-beta-D-arabino-pentofuranosyl)guanine, a potential antitumor agent against B-lymphoma infected with Kaposi's sarcoma-associated herpesvirus.

Journal of medicinal chemistry 20070503

Pharmacological properties of bivalent ligands containing butorphan linked to nalbuphine, naltrexone, and naloxone at mu, delta, and kappa opioid receptors.

Journal of medicinal chemistry 20070503

The mechanism of cyclic nucleotide hydrolysis in the phosphodiesterase catalytic site.

The journal of physical chemistry. B 20070503

172G>T variant in the 5' untranslated region of DNA repair gene RAD51 reduces risk of squamous cell carcinoma of the head and neck and interacts with a P53 codon 72 variant.

Carcinogenesis 20070501

Crystal structure of mammalian alpha1,6-fucosyltransferase, FUT8.

Glycobiology 20070501

The impact of different chelating leaving groups on the substitution kinetics of mononuclear Pt(II)(1,2-trans-R,R-diaminocyclohexane)(X-Y) complexes.

Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry 20070501

Visualization of 2-arachidonoylglycerol accumulation and cannabinoid CB1 receptor activity in rat brain cryosections by functional autoradiography.

Journal of neurochemistry 20070501

Alterations in cytoskeletal protein expression by mycophenolic acid in human mesangial cells requires Rac inactivation.

Biochemical pharmacology 20070501

Different effects of opioid antagonists on mu-, delta-, and kappa-opioid receptors with and without agonist pretreatment.

The Journal of pharmacology and experimental therapeutics 20070501

Protean agonism at the dopamine D2 receptor: (S)-3-(3-hydroxyphenyl)-N-propylpiperidine is an agonist for activation of Go1 but an antagonist/inverse agonist for Gi1,Gi2, and Gi3.

Molecular pharmacology 20070501

Quantitative evaluation of human delta opioid receptor desensitization using the operational model of drug action.

Molecular pharmacology 20070501

Evidence for the role of G-proteins in flow stimulation of dinoflagellate bioluminescence.

American journal of physiology. Regulatory, integrative and comparative physiology 20070501

Firing properties of accessory olfactory bulb mitral/tufted cells in response to urine delivered to the vomeronasal organ of gray short-tailed opossums.

Chemical senses 20070501

Biochemical anti-opioid action of NPFF2 receptors in rat spinal cord.

Neuroscience research 20070501

The in vitro pharmacology of the peripherally restricted opioid receptor antagonists, alvimopan, ADL 08-0011 and methylnaltrexone.

Naunyn-Schmiedeberg's archives of pharmacology 20070501

Guanosine 3',5'-cyclic monophosphate (cGMP)/cGMP-dependent protein kinase induce interleukin-6 transcription in osteoblasts.

Molecular endocrinology (Baltimore, Md.) 20070501

Metabotropic P2Y receptors inhibit P2X3 receptor-channels via G protein-dependent facilitation of their desensitization.

British journal of pharmacology 20070501

Mechanisms of G protein activation via the D2 dopamine receptor: evidence for persistent receptor/G protein interaction after agonist stimulation.

British journal of pharmacology 20070501

Immunoreactivity and guanosine 3',5'-cyclic monophosphate activating actions of various molecular forms of human B-type natriuretic peptide.

Hypertension (Dallas, Tex. : 1979) 20070501

Biochemical and structural characterization of mammalian-like purine nucleoside phosphorylase from the Archaeon Pyrococcus furiosus.

The FEBS journal 20070501

The role of cargo proteins in GGA recruitment.

Traffic (Copenhagen, Denmark) 20070501

The P2Y2 nucleotide receptor requires interaction with alpha v integrins to access and activate G12.

Journal of cell science 20070501

Oral donepezil reduces hypersensitivity after nerve injury by a spinal muscarinic receptor mechanism.

Anesthesiology 20070501

An antisense RNA controls synthesis of an SOS-induced toxin evolved from an antitoxin.

Molecular microbiology 20070501

Analysis of Beta-Tubulin Gene Exon 4 Mutations in Advanced Stage III or IV Gastric Cancer.

Journal of clinical biochemistry and nutrition 20070501

Probing the role of a secondary structure element at the 5'- and 3'-splice sites in group I intron self-splicing: the tetrahymena L-16 ScaI ribozyme reveals a new role of the G.U pair in self-splicing.

Biochemistry 20070424

Identification of an in vivo inhibitor of Bacillus anthracis spore germination.

The Journal of biological chemistry 20070420

Role of kappa and delta opioid receptors in mediating morphine-induced antinociception in morphine-tolerant infant rats.

Brain research 20070420

Mutational analysis of the mitochondrial tRNALeu(UUR) gene in Tunisian patients with mitochondrial diseases.

Biochemical and biophysical research communications 20070420

D- and L-2',3'-didehydro-2',3'-dideoxy-3'-fluoro-carbocyclic nucleosides: synthesis, anti-HIV activity and mechanism of resistance.

Journal of medicinal chemistry 20070419

Nearest neighbor parameters for inosine x uridine pairs in RNA duplexes.

Biochemistry 20070417

DNA-probes for the highly sensitive identification of single nucleotide polymorphism using single-molecule spectroscopy.

FEBS letters 20070417

Structure-based design of benzylamino-acridine compounds as G-quadruplex DNA telomere targeting agents.

Bioorganic & medicinal chemistry letters 20070415

Electrocatalytic oxidation of guanine, guanosine, and guanosine monophosphate.

Biophysical journal 20070415

Synthesis and structure-activity relationships of N-substituted spiropiperidines as nociceptin receptor ligands.

Bioorganic & medicinal chemistry letters 20070415

Histamine H3 and dopamine D2 receptor-mediated [35S]GTPgamma[S] binding in rat striatum: evidence for additive effects but lack of interactions.

Biochemical pharmacology 20070415

Involvement of endogenous opioid peptides in the antinociception induced by the novel dermorphin tetrapeptide analog amidino-TAPA.

European journal of pharmacology 20070410

N-Desmethylclozapine, a major clozapine metabolite, acts as a selective and efficacious delta-opioid agonist at recombinant and native receptors.

Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20070401

Synthesis and hydrolysis of pppGpp in mycobacteria: a ligand mediated conformational switch in Rel.

Biophysical chemistry 20070401

Uncovering the pharmacology of the G protein-coupled receptor GPR40: high apparent constitutive activity in guanosine 5'-O-(3-[35S]thio)triphosphate binding studies reflects binding of an endogenous agonist.

Molecular pharmacology 20070401

8-Oxoguanosine and uracil repair of nuclear and mitochondrial DNA in red and white skeletal muscle of exercise-trained old rats.

Journal of applied physiology (Bethesda, Md. : 1985) 20070401

Thienorphine: receptor binding and behavioral effects in rhesus monkeys.

The Journal of pharmacology and experimental therapeutics 20070401

G-ribo: a new structural motif in ribosomal RNA.

RNA (New York, N.Y.) 20070401

Evaluation of cellular dielectric spectroscopy, a whole-cell, label-free technology for drug discovery on Gi-coupled GPCRs.

Journal of biomolecular screening 20070401

Nitroxyl anion donor, Angeli's salt, does not develop tolerance in rat isolated aortae.

Hypertension (Dallas, Tex. : 1979) 20070401

CC12, a high-affinity ligand for [3H]cimetidine binding, is an improgan antagonist.

Neuropharmacology 20070401

Synthesis and absolute configuration of cis- and trans-opened cyclopenta[cd]pyrene 3,4-oxide N2-deoxyguanosine adducts: conversion to phosphoramidites for oligonucleotide synthesis.

Chemical research in toxicology 20070401

Natural and synthetic TLR7 ligands inhibit CpG-A- and CpG-C-oligodeoxynucleotide-induced IFN-alpha production.

Journal of immunology (Baltimore, Md. : 1950) 20070401

Regulation of GTP cyclohydrolase I expression by orphan receptor Nurr1 in cell culture and in vivo.

Journal of neurochemistry 20070401

Bidirectional regulation of mu-opioid and CB1-cannabinoid receptor in rats self-administering heroin or WIN 55,212-2.

The European journal of neuroscience 20070401

Significance of error-avoiding mechanisms for oxidative DNA damage in carcinogenesis.

Cancer science 20070401

Antioxidants to reduce sperm DNA fragmentation: an unexpected adverse effect.

Reproductive biomedicine online 20070401

How and when environmental agents and dietary factors affect the course of Alzheimer's disease: the 'LEARn' model (latent early-life associated regulation) may explain the triggering of AD.

Current Alzheimer research 20070401

Entecavir: a new nucleoside analogue for the treatment of chronic hepatitis B.

Drugs of today (Barcelona, Spain : 1998) 20070401

Approach for assessing total cellular DNA damage.

BioTechniques 20070401

Pharmacological classification of histamine H3 receptor agents across species is attributable to transmembrane 3 sequence differences.

Inflammation research : official journal of the European Histamine Research Society ... [et al.] 20070401

Dopamine D2 receptor partial agonists display differential or contrasting characteristics in membrane and cell-based assays of dopamine D2 receptor signaling.

Progress in neuro-psychopharmacology & biological psychiatry 20070330

Inhibition of G alpha i2 activation by G alpha i3 in CXCR3-mediated signaling.

The Journal of biological chemistry 20070330

Dynorphin peptides differentially regulate the human kappa opioid receptor.

Life sciences 20070320

Dimethyl sulfoxide: an antagonist in scintillation proximity assay [(35)S]-GTPgammaS binding to rat 5-HT(6) receptor cloned in HEK-293 cells?

Journal of neuroscience methods 20070315

Synthesis and in vitro binding studies of substituted piperidine naphthamides. Part I: Influence of the substitution on the basic nitrogen and the position of the amide on the affinity for D2L, D4.2, and 5-HT2A receptors.

Bioorganic & medicinal chemistry letters 20070315

High-affinity carbamate analogues of morphinan at opioid receptors.

Bioorganic & medicinal chemistry letters 20070315

G-rich proto-oncogenes are targeted for genomic instability in B-cell lymphomas.

Cancer research 20070315

Mapping pathways downstream of sphingosine 1-phosphate subtype 1 by differential chemical perturbation and proteomics.

The Journal of biological chemistry 20070309

Cordycepin (3'-deoxyadenosine) inhibits human platelet aggregation in a cyclic AMP- and cyclic GMP-dependent manner.

European journal of pharmacology 20070308

Adolescent cannabis exposure alters opiate intake and opioid limbic neuronal populations in adult rats.

Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20070301

Progressive multifocal leukoencephalopathy in purine nucleoside phosphorylase deficiency.

Brain & development 20070301

Lysophosphatidylcholine mediates melanocyte dendricity through PKCzeta activation.

The Journal of investigative dermatology 20070301

Regulation of meiotic maturation.

Journal of animal science 20070301

Phosphorylation of SIMPL modulates RelA-associated NF-kappaB-dependent transcription.

American journal of physiology. Cell physiology 20070301

Adenosine A1 and A2 receptor agonists reduce endotoxin-induced cellular energy depletion and oedema formation in the lung.

European journal of anaesthesiology 20070301

Production of GDP-L-fucose, L-fucose donor for fucosyloligosaccharide synthesis, in recombinant Escherichia coli.

Applied microbiology and biotechnology 20070301

Differential regional effects of methadone maintenance compared to heroin dependence on mu-opioid receptor desensitization in rat brain.

Synapse (New York, N.Y.) 20070301

A comparison of noninternalizing (herkinorin) and internalizing (DAMGO) mu-opioid agonists on cellular markers related to opioid tolerance and dependence.

Synapse (New York, N.Y.) 20070301

Inhibition of agonist-induced down-regulation of the delta-opioid receptor with a proteasome inhibitor attenuates opioid tolerance in human embryonic kidney 293 cells.

The Journal of pharmacology and experimental therapeutics 20070301

Native rat hippocampal 5-HT1A receptors show constitutive activity.

Molecular pharmacology 20070301

Parallel inactivation of Y2 receptor and G-proteins in CHO cells by pertussis toxin.

Regulatory peptides 20070301

Dopamine D1 receptor coupling to Gs/olf and Gq in rat striatum and cortex: a scintillation proximity assay (SPA)/antibody-capture characterization of benzazepine agonists.

Neuropharmacology 20070301

Mitogen-activated protein kinase upregulation reduces renal D1 receptor affinity and G-protein coupling in obese rats.

Kidney international 20070301

Is the repair of oxidative DNA base modifications inducible by a preceding DNA damage induction?

DNA repair 20070301

An unexpected new role of mutant Ras: perturbation of human embryonic development.

Journal of molecular medicine (Berlin, Germany) 20070301

Cannabidiol displays unexpectedly high potency as an antagonist of CB1 and CB2 receptor agonists in vitro.

British journal of pharmacology 20070301

Sildenafil reduces L-NAME-induced severe hypertension and worsening of myocardial ischaemia-reperfusion damage in the rat.

British journal of pharmacology 20070301

The psychoactive plant cannabinoid, Delta9-tetrahydrocannabinol, is antagonized by Delta8- and Delta9-tetrahydrocannabivarin in mice in vivo.

British journal of pharmacology 20070301

The fluorouridine insensitive 1 (fur1) mutant is defective in equilibrative nucleoside transporter 3 (ENT3), and thus represents an important pyrimidine nucleoside uptake system in Arabidopsis thaliana.

The Plant journal : for cell and molecular biology 20070301

Interpretation of fluorescence decay kinetics in 3-methylbenzimidazolyl(5'-5')guanosine dinucleotides: exponential dependence on the number of phosphates in the polyphosphate bridge.

European biophysics journal : EBJ 20070301

Time-resolved resonance Raman study of the reaction of the 2-fluorenylnitrenium ion with 2-fluorenylazide.

The journal of physical chemistry. A 20070301

Type 1 cytokine/chemokine production by mouse NK cells following activation of their TLR/MyD88-mediated pathways.

International immunology 20070301

Alternative splicing controls G protein-dependent inhibition of N-type calcium channels in nociceptors.

Nature neuroscience 20070301

Natriuretic peptide responsive, cyclic guanosine monophosphate producing structures in the guinea pig bladder.

The Journal of urology 20070301

Slow conformational dynamics of the guanine nucleotide-binding protein Ras complexed with the GTP analogue GTPgammaS.

The FEBS journal 20070301

Characterization of relA and codY mutants of Listeria monocytogenes: identification of the CodY regulon and its role in virulence.

Molecular microbiology 20070301

Effects of guanosine on the pharmacokinetics of acriflavine in rats following the administration of a 1:1 mixture of acriflavine and guanosine, a potential antitumor agent.

Archives of pharmacal research 20070301

P1 receptors and cytokine secretion.

Purinergic signalling 20070301

Agonist-stimulated [35S]GTPγS binding.

Current protocols in pharmacology 20070301

Probing hydrogen bonding and ion-carbonyl interactions by solid-state 17O NMR spectroscopy: G-ribbon and G-quartet.

Journal of the American Chemical Society 20070227

Direct 23Na NMR observation of mixed cations residing inside a G-quadruplex channel.

Chemical communications (Cambridge, England) 20070227

Voltammetric determination of adenosine and guanosine using fullerene-C(60)-modified glassy carbon electrode.

Talanta 20070227

Characterization of cannabinoid-binding sites in zebrafish brain.

Neuroscience letters 20070221

Microglial cells and peritoneal macrophages release activin A upon stimulation with Toll-like receptor agonists.

Neuroscience letters 20070221

In vitro studies on the binding, antioxidant, and cytotoxic actions of punicalagin.

Journal of agricultural and food chemistry 20070221

Prenatal cannabis exposure increases heroin seeking with allostatic changes in limbic enkephalin systems in adulthood.

Biological psychiatry 20070215

Functional reduction in mu-opioidergic system in the spinal cord under a neuropathic pain-like state following chronic ethanol consumption in the rat.

Neuroscience 20070209

Towards elucidation of the mechanism of UV1C, a deoxyribozyme with photolyase activity.

Journal of molecular biology 20070202

Amphetamine-induced locomotion, behavioral sensitization to amphetamine, and striatal D2 receptor function in rats with high or low spontaneous exploratory activity: differences in the role of locus coeruleus.

Brain research 20070202

Metabolic syndrome and urinary cGMP excretion in general population.

Atherosclerosis 20070201

Effect of graded corticosterone treatment on aging-related markers of oxidative stress in rat liver mitochondria.

Biogerontology 20070201

One-step purification of bacterially expressed recombinant transducin alpha-subunit and isotopically labeled PDE6 gamma-subunit for NMR analysis.

Protein expression and purification 20070201

Functional differences between NPFF1 and NPFF2 receptor coupling: high intrinsic activities of RFamide-related peptides on stimulation of [35S]GTPgammaS binding.

Neuropharmacology 20070201

Pre-synaptic histamine H3 receptors regulate glutamate, but not GABA release in rat thalamus.

Neuropharmacology 20070201

Involvement of Na,K-pump in SEPYLRFamide-mediated reduction of cholinosensitivity in Helix neurons.

Regulatory peptides 20070201

Salvinorin A: allosteric interactions at the mu-opioid receptor.

The Journal of pharmacology and experimental therapeutics 20070201

Contribution of both Ca2+ entry and Ca2+ sensitization to the alpha1-adrenergic vasoconstriction of rat penile small arteries.

American journal of physiology. Heart and circulatory physiology 20070201

SAR studies of 3-arylpropionic acids as potent and selective agonists of sphingosine-1-phosphate receptor-1 (S1P1) with enhanced pharmacokinetic properties.

Bioorganic & medicinal chemistry letters 20070201

Identification and structure-activity relationships of 1-aryl-3-piperidin-4-yl-urea derivatives as CXCR3 receptor antagonists.

Bioorganic & medicinal chemistry letters 20070201

Effect of the 252A>G polymorphism of the lymphotoxin-alpha gene on inflammatory markers of response to cigarette smoking in Korean healthy men.

Clinica chimica acta; international journal of clinical chemistry 20070201

Segment-dependent expression of muscarinic acetylcholine receptors and G-protein coupling in the equine respiratory tract.

Veterinary research communications 20070201

Self-regulation of agonist activity at the Y receptors.

Peptides 20070201

Increased brain neuropeptide Y1 and Y2 receptor binding in NPY knock out mice does not result in increased receptor function.

Peptides 20070201

Oxypurine and purine nucleoside concentrations in renal vein of allograft are potential markers of energy status of renal tissue.

Archives of medical research 20070201

The role of the omega subunit of RNA polymerase in expression of the relA gene in Escherichia coli.

FEMS microbiology letters 20070201

Loss of a conserved 7-methylguanosine modification in 16S rRNA confers low-level streptomycin resistance in bacteria.

Molecular microbiology 20070201

G protein-coupled inwardly rectifying potassium channels in dorsal root ganglion neurons.

Acta pharmacologica Sinica 20070201

Structure of radicals from X-irradiated guanine derivatives: an experimental and computational study of sodium guanosine dihydrate single crystals.

The journal of physical chemistry. B 20070201

Use of 5'-[p-(fluorosulfonyl)benzoyl] guanosine as an affinity probe for the guanine nucleotide-binding site of transducin.

The protein journal 20070201

Duodenal reflux leads to down regulation of DNA mismatch repair pathway in an animal model of esophageal cancer.

The Annals of thoracic surgery 20070201

Regulation of human internal mammary and radial artery contraction by extracellular and intracellular calcium channels and cyclic adenosine 3', 5' monophosphate.

The Annals of thoracic surgery 20070201

Supramolecular architectures generated by self-assembly of guanosine derivatives.

Chemical Society reviews 20070201

Nitric oxide and its gatekeeper thrombospondin-1 in tumor angiogenesis.

Clinical cancer research : an official journal of the American Association for Cancer Research 20070201

Disruption of noradrenergic transmission and the behavioural response to a novel environment in NK1R-/- mice.

The European journal of neuroscience 20070201

Differential stringent responses of Streptomyces coelicolor M600 to starvation of specific nutrients.

Journal of microbiology and biotechnology 20070201

Vesicoureteric reflux and tumor necrosis factor-alpha gene polymorphism.

Journal of pediatric urology 20070201

Photophysical characterization of a cytidine-guanosine tethered phthalocyanine-fullerene dyad.

Chemical communications (Cambridge, England) 20070121

Identification of dynorphin a from zebrafish: a comparative study with mammalian dynorphin A.

Neuroscience 20070119

Critical role of methionine-722 in the stimulation of human brain G-proteins and neurotoxicity induced by London familial Alzheimer's disease (FAD) mutated V717G-APP(714-723).

Neuroscience 20070119

Cooperation of DEF6 with activated Rac in regulating cell morphology.

The Journal of biological chemistry 20070119

The extracellular nucleotide UTP is a potent inducer of hematopoietic stem cell migration.

Blood 20070115

Identification of selective neuropeptide Y2 peptide agonists.

Bioorganic & medicinal chemistry letters 20070115

Guanosine inhibits CD40 receptor expression and function induced by cytokines and beta amyloid in mouse microglia cells.

Journal of immunology (Baltimore, Md. : 1950) 20070115

Kinetic conformational analysis of human 8-oxoguanine-DNA glycosylase.

The Journal of biological chemistry 20070112

Withdrawal from a single exposure to cocaine increases 5-HT2A receptor and G protein function.

Neuroreport 20070108

NMR structure of a human homologous methuselah gene receptor peptide.

Biochemical and biophysical research communications 20070105

Simultaneous determination of guanosine and guanosine-5'-triphosphate in biological sample using gold nanoparticles modified indium tin oxide electrode.

Analytica chimica acta 20070102

Genetic impairment of frontocortical endocannabinoid degradation and high alcohol preference.

Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20070101

Conformations of adducts formed between the genotoxic benzo[a]pyrene-7,8-dione and nucleosides studied by density functional theory.

Biophysical chemistry 20070101

BF2.649 [1-{3-[3-(4-Chlorophenyl)propoxy]propyl}piperidine, hydrochloride], a nonimidazole inverse agonist/antagonist at the human histamine H3 receptor: Preclinical pharmacology.

The Journal of pharmacology and experimental therapeutics 20070101

Identification of small-molecule inhibitors of RGS4 using a high-throughput flow cytometry protein interaction assay.

Molecular pharmacology 20070101

The phosphofructokinase-B (MJ0406) from Methanocaldococcus jannaschii represents a nucleoside kinase with a broad substrate specificity.

Extremophiles : life under extreme conditions 20070101

Mycophenolate acid inhibits endothelial NAD(P)H oxidase activity and superoxide formation by a Rac1-dependent mechanism.

Hypertension (Dallas, Tex. : 1979) 20070101

Effect of olive oils on biomarkers of oxidative DNA stress in Northern and Southern Europeans.

FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20070101

Nitric oxide regulates cell survival in purified cultures of avian retinal neurons: involvement of multiple transduction pathways.

Journal of neurochemistry 20070101

Gonadotropin-controlled mammal oocyte meiotic resumption.

Frontiers in bioscience : a journal and virtual library 20070101

Little or no ability of obestatin to interact with ghrelin or modify motility in the rat gastrointestinal tract.

British journal of pharmacology 20070101

Effects of serotonin on the intrinsic membrane properties of layer II medial entorhinal cortex neurons.

Hippocampus 20070101

UVA irradiation induces relocalisation of the DNA repair protein hOGG1 to nuclear speckles.

Journal of cell science 20070101

Collision-induced dissociation of cytidine and its derivatives.

Journal of mass spectrometry : JMS 20070101

JNK- and Rac1-dependent induction of immediate early gene pip92 suppresses neuronal differentiation.

Journal of neurochemistry 20070101

Homocysteine, reactive oxygen species and nitric oxide in type 2 diabetes mellitus.

Thrombosis research 20070101

Selective decrease in the DNA base excision repair pathway in squamous cell cancer of the esophagus.

The Journal of thoracic and cardiovascular surgery 20070101

Augmenting effect of serotonin on the voltage-dependent Ca2+ current and subsequently activated K+ current in Aplysia neurons.

The Tohoku journal of experimental medicine 20070101

Nitric oxide in physiologic concentrations targets the translational machinery to increase the proliferation of human breast cancer cells: involvement of mammalian target of rapamycin/eIF4E pathway.

Cancer research 20070101

Phylogenetic distribution of translational GTPases in bacteria.

BMC genomics 20070101

Nitric oxide regulates input specificity of long-term depression and context dependence of cerebellar learning.

PLoS computational biology 20070101

The supramolecular helical architecture of 8-oxoinosine and 8-oxoguanosine derivatives.

Chemistry (Weinheim an der Bergstrasse, Germany) 20070101

Self-assembly of an alkylated guanosine derivative into ordered supramolecular nanoribbons in solution and on solid surfaces.

Chemistry (Weinheim an der Bergstrasse, Germany) 20070101

GraphDNA: a Java program for graphical display of DNA composition analyses.

BMC bioinformatics 20070101

A conformationally restricted guanosine analog reveals the catalytic relevance of three structures of an RNA enzyme.

Chemistry & biology 20070101

Automated querying of genome databases.

PLoS computational biology 20070101

Exploitation of eukaryotic ubiquitin signaling pathways by effectors translocated by bacterial type III and type IV secretion systems.

PLoS pathogens 20070101

Mandatory chromosomal segment balance in aneuploid tumor cells.

BMC cancer 20070101

In vitro study of antiviral activity of mycophenolic acid on Brazilian orthobunyaviruses.

Intervirology 20070101

RhoA/Rho kinase-mediated Ca2+ sensitization in the contraction of human prostate.

Neurourology and urodynamics 20070101

Gentamicin decreases guanylyl cyclase activity in rat glomerulus.

Kidney & blood pressure research 20070101

Europium tetracycline as a luminescent probe for nucleoside phosphates and its application to the determination of kinase activity.

Chemistry (Weinheim an der Bergstrasse, Germany) 20070101

Effective inhibition of lytic development of bacteriophages lambda, P1 and T4 by starvation of their host, Escherichia coli.

BMC biotechnology 20070101

RNA-editing-mediated exon evolution.

Genome biology 20070101

A mathematical model for the adenylosuccinate synthetase reaction involved in purine biosynthesis.

Theoretical biology & medical modelling 20070101

Structural and evolutionary bioinformatics of the SPOUT superfamily of methyltransferases.

BMC bioinformatics 20070101

Developmental stage related patterns of codon usage and genomic GC content: searching for evolutionary fingerprints with models of stem cell differentiation.

Genome biology 20070101

Large-scale mapping of human protein-protein interactions by mass spectrometry.

Molecular systems biology 20070101

Interaction of 2'-deoxyguanosine triphosphate analogue inhibitors of HIV reverse transcriptase with human mitochondrial DNA polymerase gamma.

Antiviral chemistry & chemotherapy 20070101

Replicative homeostasis III: implications for antiviral therapy and mechanisms of response and non-response.

Virology journal 20070101

The biochemical analysis of methadone modulation on morphine-induced tolerance and dependence in the rat brain.

Pharmacology 20070101

Reactome: a knowledge base of biologic pathways and processes.

Genome biology 20070101

Structure, substrate recognition and reactivity of Leishmania major mevalonate kinase.

BMC structural biology 20070101

Cyclic GMP modulates the expression of Gi protein and adenylyl cyclase signaling in vascular smooth muscle cells.

Cell biochemistry and biophysics 20070101

Melatonin the 'light of night' in human biology and adolescent idiopathic scoliosis.

Scoliosis 20070101

The transcriptome analysis of early morphogenesis in Paracoccidioides brasiliensis mycelium reveals novel and induced genes potentially associated to the dimorphic process.

BMC microbiology 20070101

Mechanisms underlying vasorelaxant action of astragaloside IV in isolated rat aortic rings.

Clinical and experimental pharmacology & physiology 20070101

5-HT1A receptor agonist properties of antipsychotics determined by [35S]GTPgammaS binding in rat hippocampal membranes.

Clinical and experimental pharmacology & physiology 20070101

Oxypurine and nucleoside concentrations in renal veins during reperfusion are predictors of early graft function.

Scandinavian journal of urology and nephrology 20070101

Searching genomes for ribozymes and riboswitches.

Genome biology 20070101

Specific fluorescent probe for 8-oxoguanosine.

Angewandte Chemie (International ed. in English) 20070101

Rab4A GTPase catenin interactions are involved in cell junction dynamics in the testis.

Journal of andrology 20070101

Unexpected observations after mapping LongSAGE tags to the human genome.

BMC bioinformatics 20070101

Analysis of gene expression in cotton fiber initials.

BMC plant biology 20070101

The Arabidopsis thaliana brassinosteroid receptor (AtBRI1) contains a domain that functions as a guanylyl cyclase in vitro.

PloS one 20070101

Multitracer positron emission tomographic imaging of exogenous gene expression mediated by a universal herpes simplex virus 1 amplicon vector.

Molecular imaging 20070101

ERK1/2 inactivation and p38 MAPK-dependent caspase activation during guanosine 5'-triphosphate-mediated terminal erythroid differentiation of K562 cells.

The international journal of biochemistry & cell biology 20070101

Guanosine and inosine (riboxin) eliminate the long-lived protein radicals induced X-ray radiation.

Doklady. Biochemistry and biophysics 20070101

Control of pre-mRNA splicing by the general splicing factors PUF60 and U2AF(65).

PloS one 20070101

RNA editing and alternative splicing of the insect nAChR subunit alpha6 transcript: evolutionary conservation, divergence and regulation.

BMC evolutionary biology 20070101

Hypoxia modulates cholinergic but not opioid activation of G proteins in rat hippocampus.

Hippocampus 20070101

Modulatory effects of nitric oxide-active drugs on the anticonvulsant activity of lamotrigine in an experimental model of partial complex epilepsy in the rat.

BMC neuroscience 20070101

Traumatic injury of the spinal cord and nitric oxide.

Progress in brain research 20070101

Phosphodiesterase 5 inhibitors lower both portal and pulmonary pressure in portopulmonary hypertension: a case report.

Journal of medical case reports 20070101

Neuronal conduction of excitation without action potentials based on ceramide production.

PloS one 20070101

Nucleoside and nucleotide reverse transcriptase inhibitors in children.

Clinical drug investigation 20070101

Do motor control genes contribute to interindividual variability in decreased movement in patients with pain?

Molecular pain 20070101

Comparative genomic and bioinformatic approaches for the identification of new adenosine-to-inosine substrates.

Methods in enzymology 20070101

Evolutionary genomics of plant genes encoding N-terminal-TM-C2 domain proteins and the similar FAM62 genes and synaptotagmin genes of metazoans.

BMC genomics 20070101

New pleiotropic effects of eliminating a rare tRNA from Streptomyces coelicolor, revealed by combined proteomic and transcriptomic analysis of liquid cultures.

BMC genomics 20070101

The global role of ppGpp synthesis in morphological differentiation and antibiotic production in Streptomyces coelicolor A3(2).

Genome biology 20070101

Hitting bacteria at the heart of the central dogma: sequence-specific inhibition.

Microbial cell factories 20070101

Molecular adsorbents recirculating system treatment in acute-on-chronic hepatitis patients on the transplant waiting list improves model for end-stage liver disease scores.

Transplantation proceedings 20070101

Wrinkly-Spreader fitness in the two-dimensional agar plate microcosm: maladaptation, compensation and ecological success.

PloS one 20070101

Three-dimensional imaging of Drosophila melanogaster.

PloS one 20070101

The p53 tumor suppressor-like protein nvp63 mediates selective germ cell death in the sea anemone Nematostella vectensis.

PloS one 20070101

The cys-loop ligand-gated ion channel gene superfamily of the red flour beetle, Tribolium castaneum.

BMC genomics 20070101

Zinc-bound metallothioneins and immune plasticity: lessons from very old mice and humans.

Immunity & ageing : I & A 20070101

A genetic code alteration is a phenotype diversity generator in the human pathogen Candida albicans.

PloS one 20070101

[Perturbations of the vesicle cycle in reticulospinal synapses of axons in lamprey after presynaptic microinjections of GTPgammaS].

Tsitologiia 20070101

Transcriptional networks in plasmacytoid dendritic cells stimulated with synthetic TLR 7 agonists.

BMC immunology 20070101

A new function for the Bacillus PbuE purine base efflux pump: efflux of purine nucleosides.

Research in microbiology 20070101

Microglial cells in astroglial cultures: a cautionary note.

Journal of neuroinflammation 20070101

The possible role of the ubiquitin proteasome system in the development of atherosclerosis in diabetes.

Cardiovascular diabetology 20070101

Translation initiation region sequence preferences in Escherichia coli.

BMC molecular biology 20070101

Increased ROS generation in subsets of OGG1 knockout fibroblast cells.

Mechanisms of ageing and development 20070101

The chemistry and biology of RNA editing by adenosine deaminases.

Nucleic acids symposium series (2004) 20070101

Synthesis of a guanosine phosphoramidite derivative containing a photocleavable protecting group at the O6 position via regioselective protection of the 2'-hydroxy group with a TBDMS group.

Nucleic acids symposium series (2004) 20070101

Development of a specific fluorescent probe for 8-oxoguanosine.

Nucleic acids symposium series (2004) 20070101

Metabolic signature of breast cancer cell line MCF-7: profiling of modified nucleosides via LC-IT MS coupling.

BMC biochemistry 20070101

Codon-triplet context unveils unique features of the Candida albicans protein coding genome.

BMC genomics 20070101

OrthoMaM: a database of orthologous genomic markers for placental mammal phylogenetics.

BMC evolutionary biology 20070101

New analogs of acyclovir substituted at the side chain.

Nucleosides, nucleotides & nucleic acids 20070101

Synthesis of enantiopure pseudo-L-vinylcyclopropyl nucleosides bearing quaternary carbon as potential anti-herpesvirus agent.

Nucleosides, nucleotides & nucleic acids 20070101

Synthesis and biophysical characterization of G-rich oligonucleotides conjugated with sugar-phosphate tails.

Nucleosides, nucleotides & nucleic acids 20070101

Synthesis and characterization of tetra-end linked oligonucleotides capable of forming monomolecular G-quadruplexes.

Nucleosides, nucleotides & nucleic acids 20070101

Assignment of the absolute configuration of P-chiral 5' mRNA cap analogues containing phosphorothioate moiety.

Nucleosides, nucleotides & nucleic acids 20070101

Synthesis of 3H and 13C labeled mRNA cap dinucleotides--useful tools for NMR, biochemical, and biological studies.

Nucleosides, nucleotides & nucleic acids 20070101

Mismatch discrimination of base-modified nucleic acids and their constituents: non-Watson-Crick base pairing induced by tautomerization.

Nucleosides, nucleotides & nucleic acids 20070101

Discovery of ANA975: an oral prodrug of the TLR-7 agonist isatoribine.

Nucleosides, nucleotides & nucleic acids 20070101

Selective fluorescence detection of 8-oxoguanosine with 8-oxoG-clamp.

Nucleosides, nucleotides & nucleic acids 20070101

Interactions of calf spleen purine nucleoside phosphorylase with formycin B and its aglycone - spectroscopic and kinetic studies.

Nucleosides, nucleotides & nucleic acids 20070101

Cannabinoid CB(2)-selective inverse agonist protects against antigen-induced bone loss.

Immunopharmacology and immunotoxicology 20070101

Disruption of the plasma membrane integrity by cholesterol depletion impairs effectiveness of TRH receptor-mediated signal transduction via G(q)/G(11)alpha proteins.

Journal of receptor and signal transduction research 20070101

A scenario on the stepwise evolution of the genetic code.

Genomics, proteomics & bioinformatics 20070101

Synthesis of Novel 3-Aryl-N-Methyl-1,2,5,6-Tetrahydropyridine Derivatives by Suzuki coupling: As Acetyl Cholinesterase Inhibitors.

The open medicinal chemistry journal 20070101

DNA methylation in circulating tumour DNA as a biomarker for cancer.

Biomarker insights 20070101

Gene expression profiling in familial adenomatous polyposis adenomas and desmoid disease.

Hereditary cancer in clinical practice 20070101

Effect of ribavirin alone or combined with silymarin on carbon tetrachloride induced hepatic damage in rats.

Drug target insights 20070101

Disruption of RhoGDI and RhoA regulation by a Rac1 specificity switch mutant.

The Journal of biological chemistry 20061229

Active site labeling of G8 in the hairpin ribozyme: implications for structure and mechanism.

Journal of the American Chemical Society 20061227

A facile two-step synthesis of 8-arylated guanosine mono- and triphosphates (8-aryl GXPs).

Organic & biomolecular chemistry 20061221

In vitro characterization of SLV308 (7-[4-methyl-1-piperazinyl]-2(3H)-benzoxazolone, monohydrochloride): a novel partial dopamine D2 and D3 receptor agonist and serotonin 5-HT1A receptor agonist.

Synapse (New York, N.Y.) 20061215

Aplindore (DAB-452), a high affinity selective dopamine D2 receptor partial agonist.

European journal of pharmacology 20061215

Cell-based indicator to visualize picomolar dynamics of nitric oxide release from living cells.

Analytical chemistry 20061215

Adrenal hyperplasia and adenomas are associated with inhibition of phosphodiesterase 11A in carriers of PDE11A sequence variants that are frequent in the population.

Cancer research 20061215

High-throughput screening for functional adenosine to inosine RNA editing systems.

ACS chemical biology 20061215

Elucidation of the bioactive conformation of the N-substituted trans-3,4-dimethyl-4-(3-hydroxyphenyl)piperidine class of mu-opioid receptor antagonists.

Journal of medicinal chemistry 20061214

Synthesis and pharmacological evaluation of novel octahydro-1H-pyrido[1,2-a]pyrazine as mu-opioid receptor antagonists.

Journal of medicinal chemistry 20061214

Design and synthesis of N-(3,3-diphenylpropenyl)alkanamides as a novel class of high-affinity MT2-selective melatonin receptor ligands.

Journal of medicinal chemistry 20061214

Asymmetric conformational changes in a GPCR dimer controlled by G-proteins.

The EMBO journal 20061213

Kinetics and mechanism of the oxidation of guanosine derivatives by Pt(IV) complexes.

Inorganic chemistry 20061211

Molecular basis of differences among statins and a comparison with antioxidant vitamins.

The American journal of cardiology 20061204

A case of late-onset Segawa syndrome (autosomal dominant dopa-responsive dystonia) with a novel mutation of the GTP-cyclohydrase I (GCH1) gene.

Clinical neurology and neurosurgery 20061201

Clinical evidence for lead-induced inhibition of nitric oxide formation.

Archives of toxicology 20061201

Profiles of purine biosynthesis, salvage and degradation in disks of potato (Solanum tuberosum L.) tubers.

Planta 20061201

Characterisation of the novel restriction endonuclease SuiI from Sulfolobus islandicus.

Extremophiles : life under extreme conditions 20061201

Impaired cerebrovascular reactivity after cortical spreading depression in rats: Restoration by nitric oxide or cGMP.

Experimental neurology 20061201

Mechanisms underlying type I mGluR-induced activation of lobster gastric mill neurons.

Journal of neurophysiology 20061201

Point mutations in the transmembrane region of GABAB2 facilitate activation by the positive modulator N,N'-dicyclopentyl-2-methylsulfanyl-5-nitro-pyrimidine-4,6-diamine (GS39783) in the absence of the GABAB1 subunit.

Molecular pharmacology 20061201

Pain sensitivity is altered in animals after subchronic ketamine treatment.

Psychopharmacology 20061201

Evidence that corticotropin-releasing factor receptor type 1 couples to Gs- and Gi-proteins through different conformations of its J-domain.

British journal of pharmacology 20061201

Activation of nematode G protein GOA-1 by the human muscarinic acetylcholine receptor M2 subtype. Functional coupling of G-protein-coupled receptor and G protein originated from evolutionarily distant animals.

The FEBS journal 20061201

Dynamic roles for G4 DNA in the biology of eukaryotic cells.

Nature structural & molecular biology 20061201

Mycophenolic acid induces islet apoptosis by regulating mitogen-activated protein kinase activation.

Transplantation proceedings 20061201

Erythrocyte G protein as a novel target for malarial chemotherapy.

PLoS medicine 20061201

Fz2 and cdc42 mediate melanization and actin polymerization but are dispensable for Plasmodium killing in the mosquito midgut.

PLoS pathogens 20061201

Regulation of cGMP synthesis in cultured podocytes by vasoactive hormones.

Journal of physiology and pharmacology : an official journal of the Polish Physiological Society 20061201

Determination of the impurity profile of adenosine by means of ion-pair reversed-phase chromatography.

Pharmeuropa scientific notes 20061201

Nanomedicines in the treatment of patients with hepatitis C co-infected with HIV--focus on pegylated interferon-alpha.

International journal of nanomedicine 20061201

Sildenafil in the treatment of erectile dysfunction: an overview of the clinical evidence.

Clinical interventions in aging 20061201

Azacytidine (Vidaza(R)) in the treatment of myelodysplastic syndromes.

Therapeutics and clinical risk management 20061201

Numerical characterization of DNA sequences based on the k-step Markov chain transition probability.

Journal of computational chemistry 20061130

3-Hydrogenkwadaphnin induces monocytic differentiation and enhances retinoic acid-mediated granulocytic differentiation in NB4 cell line.

Journal of biochemistry and molecular biology 20061130

Cation exchange in lipophilic G-quadruplexes: not all ion binding sites are equal.

Journal of the American Chemical Society 20061129

Mutational analysis of Encephalitozoon cuniculi mRNA cap (guanine-N7) methyltransferase, structure of the enzyme bound to sinefungin, and evidence that cap methyltransferase is the target of sinefungin's antifungal activity.

The Journal of biological chemistry 20061124

Investigation of guanosine-quartet assemblies by vibrational and electronic circular dichroism spectroscopy, a novel approach for studying supramolecular entities.

Chemistry (Weinheim an der Bergstrasse, Germany) 20061124

The rewards of nicotine: regulation by tissue plasminogen activator-plasmin system through protease activated receptor-1.

The Journal of neuroscience : the official journal of the Society for Neuroscience 20061122

BRAG1, a Sec7 domain-containing protein, is a component of the postsynaptic density of excitatory synapses.

Brain research 20061120

Identification of Escherichia coli m2G methyltransferases: II. The ygjO gene encodes a methyltransferase specific for G1835 of the 23 S rRNA.

Journal of molecular biology 20061117

Medium-chain fatty acids as ligands for orphan G protein-coupled receptor GPR84.

The Journal of biological chemistry 20061110

Broad-spectrum effects of 4-aminopyridine to modulate amyloid beta1-42-induced cell signaling and functional responses in human microglia.

The Journal of neuroscience : the official journal of the Society for Neuroscience 20061108

Characterization and quantification of eight water-soluble constituents in tubers of Pinellia ternata and in tea granules from the Chinese multiherb remedy Xiaochaihu-tang.

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20061107

Brain G protein-dependent signaling pathways in Down syndrome and Alzheimer's disease.

Amino acids 20061101

Effect of chronic ethanol exposure and its withdrawal on the endocannabinoid system.

Neurochemistry international 20061101

Functional expression of the GABAB receptor in human airway smooth muscle.

American journal of physiology. Lung cellular and molecular physiology 20061101

Methamphetamine-induced behavioral sensitization in mice: alterations in mu-opioid receptor.

Journal of biomedical science 20061101

Mechanism-based pharmacokinetic-pharmacodynamic modeling of the respiratory-depressant effect of buprenorphine and fentanyl in rats.

The Journal of pharmacology and experimental therapeutics 20061101

Probing the existence of G protein-coupled receptor dimers by positive and negative ligand-dependent cooperative binding.

Molecular pharmacology 20061101

Unaltered neuropeptide Y (NPY)-stimulated [35S]GTPgammaS binding suggests a net increase in NPY signalling after repeated electroconvulsive seizures in mice.

Journal of neuroscience research 20061101

Differential involvement of the endocannabinoid system in short- and long-term expression of incentive learning supported by nicotine in rats.

Psychopharmacology 20061101

Cooperation of phosphoinositides and BAR domain proteins in endosomal tubulation.

Traffic (Copenhagen, Denmark) 20061101

Store-operated Ca2+ influx in airway smooth muscle: Interactions between volatile anesthetic and cyclic nucleotide effects.

Anesthesiology 20061101

Natural resistance to HIV infection: The Vif-APOBEC interaction.

Comptes rendus biologies 20061101

Acyl carrier protein/SpoT interaction, the switch linking SpoT-dependent stress response to fatty acid metabolism.

Molecular microbiology 20061101

Adenosine-to-inosine RNA editing: perspectives and predictions.

Mini reviews in medicinal chemistry 20061101

Mycophenolic acid inhibits hepatitis C virus replication and acts in synergy with cyclosporin A and interferon-alpha.

Gastroenterology 20061101

Chlorine dioxide oxidation of guanosine 5'-monophosphate.

Chemical research in toxicology 20061101

Molecular mechanisms involved in anti-inflammatory effects of proton pump inhibitors.

Inflammation research : official journal of the European Histamine Research Society ... [et al.] 20061101

In vitro and in vivo studies of ribavirin action on Brazilian Orthobunyavirus.

The American journal of tropical medicine and hygiene 20061101

Imipramine inhibits A-type delayed rectifier and ATP-sensitive K+ currents independent of G-protein and protein kinase C in murine proximal colonic myocytes.

Archives of pharmacal research 20061101

First joint italian-german purine club meeting 'progress in purinergic receptor pharmacology and function'.

Purinergic signalling 20061101

Roles of P2 receptors in glial cells: focus on astrocytes.

Purinergic signalling 20061101

Signal transduction events induced by extracellular guanosine 5' triphosphate in excitable cells.

Purinergic signalling 20061101

Guanosine effect on cholesterol efflux and apolipoprotein E expression in astrocytes.

Purinergic signalling 20061101

Non-adenine based purines accelerate wound healing.

Purinergic signalling 20061101

Recent advances in structure and function of cytosolic IMP-GMP specific 5'-nucleotidase II (cN-II).

Purinergic signalling 20061101

Interaction of neurochondrin with the melanin-concentrating hormone receptor 1 interferes with G protein-coupled signal transduction but not agonist-mediated internalization.

The Journal of biological chemistry 20061027

Acid-base and metal-ion-binding properties of xanthosine 5'-monophosphate (XMP) in aqueous solution: complex stabilities, isomeric equilibria, and extent of macrochelation.

Chemistry (Weinheim an der Bergstrasse, Germany) 20061025

Tautomerism in the guanyl radical.

Journal of the American Chemical Society 20061025

Chronic activation of spinal adenosine A1 receptors results in hypersensitivity.

Neuroreport 20061023

Characterization of the reactivity determinants of a novel hairpin substrate of yeast RNase III.

Journal of molecular biology 20061020

Structure-activity relationship of quinoline derivatives as potent and selective alpha(2C)-adrenoceptor antagonists.

Journal of medicinal chemistry 20061019

Base and phosphate electron detachment energies of deoxyribonucleotide anions.

Journal of the American Chemical Society 20061018

Modulation of dopamine D1 receptor signaling by adenosine A1 receptors in Sf9 cells requires expression of Gi proteins.

Neuroscience letters 20061009

On the physical nature of mesophases of guanosine gels.

Physical chemistry chemical physics : PCCP 20061007

Design, synthesis, and biological evaluation of new 1,8-naphthyridin-4(1H)-on-3-carboxamide and quinolin-4(1H)-on-3-carboxamide derivatives as CB2 selective agonists.

Journal of medicinal chemistry 20061005

Structural determinants of opioid activity in derivatives of 14-aminomorphinones: effects of changes to the chain linking of the C14-amino group to the aryl ring.

Journal of medicinal chemistry 20061005

Evolution of new function in the GTP cyclohydrolase II proteins of Streptomyces coelicolor.

Biochemistry 20061003

Mechanism of inhibition of TREK-2 (K2P10.1) by the Gq-coupled M3 muscarinic receptor.

American journal of physiology. Cell physiology 20061001

Synthesis and pharmacological studies of new hybrid derivatives of fentanyl active at the mu-opioid receptor and I2-imidazoline binding sites.

Bioorganic & medicinal chemistry 20061001

Separation of binding affinity and intrinsic activity of the potent mu-opioid 14-methoxymetopon.

The Journal of pharmacology and experimental therapeutics 20061001

Y(4) receptors mediate the inhibitory responses of pancreatic polypeptide in human and mouse colon mucosa.

The Journal of pharmacology and experimental therapeutics 20061001

Differential effects of 5-methyl-1-[[2-[(2-methyl-3-pyridyl)oxyl]-5-pyridyl]carbamoyl]-6-trifluoromethylindone (SB 243213) on 5-hydroxytryptamine(2C) receptor-mediated responses.

The Journal of pharmacology and experimental therapeutics 20061001

Assays for enhanced activity of low efficacy partial agonists at the D(2) dopamine receptor.

British journal of pharmacology 20061001

Characterization of reactions of antimoniate and meglumine antimoniate with a guanine ribonucleoside at different pH.

Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine 20061001

Relationship between systemic nitric oxide metabolites and cyclic GMP in healthy male volunteers.

Acta physiologica (Oxford, England) 20061001

In vitro and in vivo pharmacology of synthetic olivetol- or resorcinol-derived cannabinoid receptor ligands.

British journal of pharmacology 20061001

Predicting essential components of signal transduction networks: a dynamic model of guard cell abscisic acid signaling.

PLoS biology 20061001

Antinociception by spinal and systemic oxycodone: why does the route make a difference? In vitro and in vivo studies in rats.

Anesthesiology 20061001

Antiviral treatment of hepatitis C.

Expert opinion on pharmacotherapy 20061001

Nuclear magnetic resonance studies of the 4R and 4S diastereomers of spiroiminodihydantoin 2'-deoxyribonucleosides: absolute configuration and conformational features.

Chemical research in toxicology 20061001

Mechanism of PNA transport to the nuclear compartment.

Annals of the New York Academy of Sciences 20061001

Identification and characterization of a second, inducible promoter of relA in Escherichia coli.

Genes & genetic systems 20061001

[Studies on chemical constituents in flower of Abelmoschus manihot].

Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20061001

A kinetic, modeling and mechanistic re-analysis of thymidine phosphorylase and some related enzymes.

Journal of enzyme inhibition and medicinal chemistry 20061001

CpG-induced IFNgamma expands TLR4-specific IL-18 responses in vivo.

Cellular immunology 20061001

Dopamine D2 receptor-mediated G protein activation assessed by agonist-stimulated [35S]guanosine 5'-O-(gamma-thiotriphosphate) binding in rat striatal membranes.

Progress in neuro-psychopharmacology & biological psychiatry 20060930

GTP induces S-phase cell-cycle arrest and inhibits DNA synthesis in K562 cells but not in normal human peripheral lymphocytes.

Journal of biochemistry and molecular biology 20060930

Cortical feedback to the thalamus is selectively enhanced by nitric oxide.

Neuroscience 20060929

Aripiprazole and its human metabolite are partial agonists at the human dopamine D2 receptor, but the rodent metabolite displays antagonist properties.

European journal of pharmacology 20060928

Progestins' effects on sexual behaviour of female rats and hamsters involving D1 and GABA(A) receptors in the ventral tegmental area may be G-protein-dependent.

Behavioural brain research 20060925

Coupling of ORL1 (NOP) receptor to G proteins is decreased in the nucleus accumbens of anxious relative to non-anxious mice.

Brain research 20060919

Cross-linking transglutaminases with G protein-coupled receptor signaling.

Science's STKE : signal transduction knowledge environment 20060919

Different receptors mediate the electrophysiological and growth cone responses of an identified neuron to applied dopamine.

Neuroscience 20060915

Mycophenolic acid inhibits mesangial cell activation through p38 MAPK inhibition.

Life sciences 20060913

Analysis of brain adrenergic receptors in dopamine-beta-hydroxylase knockout mice.

Brain research 20060913

A cannabinoid receptor 1 mutation proximal to the DRY motif results in constitutive activity and reveals intramolecular interactions involved in receptor activation.

Brain research 20060907

Formation of a miscible supramolecular polymer blend through self-assembly mediated by a quadruply hydrogen-bonded heterocomplex.

Journal of the American Chemical Society 20060906

Targeted guanine oxidation by a dinuclear copper(II) complex at single stranded/double stranded DNA junctions.

Inorganic chemistry 20060904

Chemistry of HIV-1 virucidal Pt complexes having neglected bidentate sp2 N-donor carrier ligands with linked triazine and pyridine rings. synthesis, NMR spectral features, structure, and reaction with guanosine.

Inorganic chemistry 20060904

The very C-terminus of PRK1/PKN is essential for its activation by RhoA and downstream signaling.

Cellular signalling 20060901

Crystal structures of GMP kinase in complex with ganciclovir monophosphate and Ap5G.

Biochimie 20060901

Pharmacological characterization of novel water-soluble cannabinoids.

The Journal of pharmacology and experimental therapeutics 20060901

Prolonged recovery rate of CB1 receptor adaptation after cessation of long-term cannabinoid administration.

Molecular pharmacology 20060901

Regional differences in the coupling of 5-hydroxytryptamine-1A receptors to G proteins in the rat brain.

Molecular pharmacology 20060901

Antinociceptive activity of chemical congeners of improgan: optimization of side chain length leads to the discovery of a new, potent, non-opioid analgesic.

Neuropharmacology 20060901

A guanylate kinase/HSV-1 thymidine kinase fusion protein enhances prodrug-mediated cell killing.

Gene therapy 20060901

SB-699551-A (3-cyclopentyl-N-[2-(dimethylamino)ethyl]-N-[(4'-{[(2-phenylethyl)amino]methyl}-4-biphenylyl)methyl]propanamide dihydrochloride), a novel 5-ht5A receptor-selective antagonist, enhances 5-HT neuronal function: Evidence for an autoreceptor role for the 5-ht5A receptor in guinea pig brain.

Neuropharmacology 20060901

DRD2/DARPP-32 expression correlates with lymph node metastasis and tumor progression in patients with esophageal squamous cell carcinoma.

World journal of surgery 20060901

CYK-4/GAP provides a localized cue to initiate anteroposterior polarity upon fertilization.

Science (New York, N.Y.) 20060901

AIB1 promotes DNA replication by JNK repression and AKT activation during cellular stress.

Journal of biochemistry 20060901

Muscarinic receptor-activated cationic channels in murine ileal myocytes.

British journal of pharmacology 20060901

A distributed chemosensory circuit for oxygen preference in C. elegans.

PLoS biology 20060901

Structural basis for the interaction of CCR5 with a small molecule, functionally selective CCR5 agonist.

Journal of immunology (Baltimore, Md. : 1950) 20060901

Guanosine 5'-triphosphate induces differentiation-dependent apoptosis in human leukemia U937 and KG1 cells.

Acta pharmacologica Sinica 20060901

Structure of Methanocaldococcus jannaschii nucleoside kinase: an archaeal member of the ribokinase family.

Acta crystallographica. Section D, Biological crystallography 20060901

Human trabecular meshwork cells express functional serotonin-2A (5HT2A) receptors: role in IOP reduction.

Investigative ophthalmology & visual science 20060901

Designing siRNA that distinguish between genes that differ by a single nucleotide.

PLoS genetics 20060901

Metabolic loading of guanosine induces chondrocyte apoptosis via the Fas pathway.

Experimental & molecular medicine 20060831

Changes in CB1 receptors in motor-related brain structures of chronic relapsing experimental allergic encephalomyelitis mice.

Brain research 20060830

Serotonin 1a receptor and associated G-protein activation in schizophrenia and bipolar disorder.

Psychiatry research 20060830

Chronic morphine administration results in tolerance to delta opioid receptor-mediated antinociception.

Neuroscience 20060825

Alterations of the expression and activity of midbrain nitric oxide synthase and soluble guanylyl cyclase in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced Parkinsonism in mice.

Neuroscience 20060825

Synthetic functional pi-stack architecture in lipid bilayers.

Organic & biomolecular chemistry 20060821

Syntheses, pi-stacking interactions and base-pairings of uracil pyridinium salts and uracilyl betaines with nucleobases.

Organic & biomolecular chemistry 20060821

Comparison of ribonucleic acid homopolymer ionization energies and charge injection barriers.

The journal of physical chemistry. B 20060817

G-quartet formation from an N2-modified guanosine derivative.

Organic letters 20060817

Evaluation of two novel tag-based labelling technologies for site-specific modification of proteins.

International journal of biological macromolecules 20060815

Unique presynaptic and postsynaptic roles of Group II metabotropic glutamate receptors in the modulation of thalamic network activity.

Neuroscience 20060811

Guanine oxidation: one- and two-electron reactions.

Chemistry (Weinheim an der Bergstrasse, Germany) 20060807

Base triplet nonisomorphism strongly influences DNA triplex conformation: effect of nonisomorphic G* GC and A* AT triplets and bending of DNA triplexes.

Biopolymers 20060805

Kynurenic acid as a ligand for orphan G protein-coupled receptor GPR35.

The Journal of biological chemistry 20060804

Solventless protocol for efficient bis-N-boc protection of adenosine, cytidine, and guanosine derivatives.

The Journal of organic chemistry 20060804

Synthesis, oxidation behavior, crystallization and structure of 2'-methylseleno guanosine containing RNAs.

Journal of the American Chemical Society 20060802

Functional interactions between the alpha1b-adrenoceptor and Galpha11 are compromised by de-palmitoylation of the G protein but not of the receptor.

Cellular signalling 20060801

Linking the nutritional status of Streptococcus pyogenes to alteration of transcriptional gene expression: the action of CodY and RelA.

International journal of medical microbiology : IJMM 20060801

Correlation between a gene polymorphism of tumor necrosis factor-alpha (G/A) and end-stage renal disease: a pilot study from north India.

Clinica chimica acta; international journal of clinical chemistry 20060801

Serum antiguanosine antibodies as a marker for SLE disease activity and pathogen potential.

Clinica chimica acta; international journal of clinical chemistry 20060801

Synthesis, cannabinoid receptor activity, and enzymatic stability of reversed amide derivatives of arachidonoyl ethanolamide.

Bioorganic & medicinal chemistry 20060801

Differences in kinetics of xanomeline binding and selectivity of activation of G proteins at M(1) and M(2) muscarinic acetylcholine receptors.

Molecular pharmacology 20060801

Mu-delta opioid receptor functional interaction: Insight using receptor-G protein fusions.

The Journal of pharmacology and experimental therapeutics 20060801

The phosphoenolpyruvate carboxykinase of Mycobacterium tuberculosis induces strong cell-mediated immune responses in mice.

Molecular and cellular biochemistry 20060801

In-source CID of guanosine: gas phase ion-molecule reactions.

Journal of the American Society for Mass Spectrometry 20060801

Differentiation of 2'-O- and 3'-O-methylated ribonucleosides by tandem mass spectrometry.

Journal of the American Society for Mass Spectrometry 20060801

Dietary antioxidants and beneficial effect on oxidatively damaged DNA.

Free radical biology & medicine 20060801

Assembly and protection of the radical enzyme, methylmalonyl-CoA mutase, by its chaperone.

Biochemistry 20060801

The mitochondrial DNA A3243A>G mutation must be an infrequent cause of Asperger syndrome.

The Journal of pediatrics 20060801

Retinal vein occlusion associated with antithrombin deficiency secondary to a novel G9840C missense mutation.

Archives of ophthalmology (Chicago, Ill. : 1960) 20060801

[McCune-Albright syndrome: a difficult and complicated case study].

Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics 20060801

Masked oral prodrugs of toll-like receptor 7 agonists: a new approach for the treatment of infectious disease.

Current opinion in investigational drugs (London, England : 2000) 20060801

From field to health: a simple way to increase the nutraceutical content of grape as shown by NO-dependent vascular relaxation.

Journal of agricultural and food chemistry 20060726

Genetic damage in cultured human keratinocytes stressed by long-term exposure to areca nut extracts.

Mutation research 20060725

Methylation and repeats in silent and nonsense mutations of p53.

Mutation research 20060725

Activation of the purine salvage pathway in mononuclear cells of cardiac recipients treated with mycophenolate mofetil.

Transplantation 20060715

MTH1, an oxidized purine nucleoside triphosphatase, prevents the cytotoxicity and neurotoxicity of oxidized purine nucleotides.

DNA repair 20060713

The high binding affinity of human ribosomal protein S3 to 7,8-dihydro-8-oxoguanine is abrogated by a single amino acid change.

DNA repair 20060713

NMR structure of an intracellular loop peptide derived from prostaglandin EP3alpha receptor.

Biochemical and biophysical research communications 20060707

Reversible interconversion between a supramolecular polymer and a discrete octameric species from a guanosine derivative by dynamic cation binding and release.

Organic letters 20060706

Chemical carcinogens in non-enzymatic cytosine deamination: 3-isocyanatoacrylonitrile.

Journal of molecular modeling 20060701

Levels of G-protein alpha q/11 subunits and of phospholipase C-beta(1-4), -gamma, and -delta1 isoforms in postmortem human brain caudate and cortical membranes: potential functional implications.

Neurochemistry international 20060701

Structural studies and mechanism of Saccharomyces cerevisiae dolichyl-phosphate-mannose synthase: insights into the initial step of synthesis of dolichyl-phosphate-linked oligosaccharide chains in membranes of endoplasmic reticulum.

Glycobiology 20060701

High accumulation of platinum-DNA adducts in strial marginal cells of the cochlea is an early event in cisplatin but not carboplatin ototoxicity.

Molecular pharmacology 20060701

Thienorphine is a potent long-acting partial opioid agonist: a comparative study with buprenorphine.

The Journal of pharmacology and experimental therapeutics 20060701

Sphingosine and its analog, the immunosuppressant 2-amino-2-(2-[4-octylphenyl]ethyl)-1,3-propanediol, interact with the CB1 cannabinoid receptor.

Molecular pharmacology 20060701

Contribution of multidrug resistance protein MRP5 in control of cyclic guanosine 5'-monophosphate intracellular signaling in anterior pituitary cells.

Endocrinology 20060701

Transmembrane signaling through phospholipase C-beta in the developing human prefrontal cortex.

Journal of neuroscience research 20060701

In vitro and in vivo characterization of F-97013-GD, a partial 5-HT1A agonist with antipsychotic- and antiparkinsonian-like properties.

Neuropharmacology 20060701

A highly selective kappa-opioid receptor agonist with low addictive potential and dependence liability.

Bioorganic & medicinal chemistry letters 20060701

Pregnancy and estradiol modulate myometrial G-protein pathways in the guinea pig.

American journal of obstetrics and gynecology 20060701

In vitro biochemical evidence that the psychotomimetics phencyclidine, ketamine and dizocilpine (MK-801) are inactive at cloned human and rat dopamine D2 receptors.

European journal of pharmacology 20060701

Inhibition of dengue virus replication by mycophenolic acid and ribavirin.

The Journal of general virology 20060701

Modulating responsiveness of human TLR7 and 8 to small molecule ligands with T-rich phosphorothiate oligodeoxynucleotides.

European journal of immunology 20060701

Mass spectrometric identification and characterization of antimony complexes with ribose-containing biomolecules and an RNA oligomer.

Analytical and bioanalytical chemistry 20060701

The role of the RhoA/Rho-kinase signaling pathway in renal vascular reactivity in endothelial nitric oxide synthase null mice.

Journal of hypertension 20060701

Guanosine promotes the up-regulation of inward rectifier potassium current mediated by Kir4.1 in cultured rat cortical astrocytes.

Journal of neurochemistry 20060701

Calcium-stimulated guanosine--inosine nucleosidase from yellow lupin (Lupinus luteus).

Phytochemistry 20060701

Different nucleobase orientations in two cyclic 2',3'-phosphates of purine ribonucleosides: Et(3)NH(2',3'-cAMP) and Et(3)NH(2',3'-cGMP)xH(2)O.

Acta crystallographica. Section C, Crystal structure communications 20060701

Single-molecule dynamics reveals cooperative binding-folding in protein recognition.

PLoS computational biology 20060701

Assignment of absolute configurations of the enantiomeric spiroiminodihydantoin nucleobases by experimental and computational optical rotatory dispersion methods.

Chemical research in toxicology 20060701

Peptides derived from HIV-1, HIV-2, Ebola virus, SARS coronavirus and coronavirus 229E exhibit high affinity binding to the formyl peptide receptor.

Biochimica et biophysica acta 20060701

Analysis of internal motions of RNase T1 complexed with a productive substrate involving 15N NMR relaxation measurements.

Journal of biochemistry 20060701

Muscarinic receptor function, density and G-protein coupling in the overactive diabetic rat bladder.

Autonomic & autacoid pharmacology 20060701

Inhibition of the phosphatidylinositol 3-kinase/mammalian target of rapamycin pathway in hematologic malignancies.

Current treatment options in oncology 20060701

Enhanced expression of Gialpha protein and adenylyl cyclase signaling in aortas from 1 kidney 1 clip hypertensive rats.

Canadian journal of physiology and pharmacology 20060701

mRNA 3' of the A site bound codon is located close to protein S3 on the human 80S ribosome.

RNA biology 20060701

Activation of the mu-opiate receptor by Vitex agnus-castus methanol extracts: implication for its use in PMS.

Journal of ethnopharmacology 20060630

A novel role for cyclic guanosine 3',5'monophosphate signaling in synaptic plasticity: a selective suppressor of protein kinase A-dependent forms of long-term potentiation.

Neuroscience 20060630

2-[(4-phenylpiperazin-1-yl)methyl]imidazo(di)azines as selective D4-ligands. Induction of penile erection by 2-[4-(2-methoxyphenyl)piperazin-1-ylmethyl]imidazo[1,2-a]pyridine (PIP3EA), a potent and selective D4 partial agonist.

Journal of medicinal chemistry 20060629

[(35)S]GTPgammaS binding stimulated by endomorphin-2 and morphiceptin analogs.

Biochemical and biophysical research communications 20060623

Phototransduction in a transgenic mouse model of Nougaret night blindness.

The Journal of neuroscience : the official journal of the Society for Neuroscience 20060621

Up-regulation of the angiotensin II type 1 receptor by the MAS proto-oncogene is due to constitutive activation of Gq/G11 by MAS.

The Journal of biological chemistry 20060616

YC-1 induces S cell cycle arrest and apoptosis by activating checkpoint kinases.

Cancer research 20060615

Opioid mu receptor activation inhibits sodium currents in prefrontal cortical neurons via a protein kinase A- and C-dependent mechanism.

Brain research 20060613

Three conserved guanosines approach the reaction site in native and minimal hammerhead ribozymes.

Biochemistry 20060613

Relevance of brain natriuretic peptide in preload-dependent regulation of cardiac sarcoplasmic reticulum Ca2+ ATPase expression.

Circulation 20060613

Reconstitution of recycling from the phagosomal compartment in streptolysin O-permeabilized macrophages: role of Rab11.

Experimental cell research 20060610

A conditional mutant deficient in hypoxanthine-guanine phosphoribosyltransferase and xanthine phosphoribosyltransferase validates the purine salvage pathway of Leishmania donovani.

The Journal of biological chemistry 20060609

Universal initiator nucleotides for the enzymatic synthesis of 5'-amino- and 5'-thiol-modified RNA.

Biochemical and biophysical research communications 20060609

The exocyclic amine at the RNase P cleavage site contributes to substrate binding and catalysis.

Journal of molecular biology 20060609

Modified nucleosides: an accurate tumour marker for clinical diagnosis of cancer, early detection and therapy control.

British journal of cancer 20060605

The intron 1 of HPV 16 has a suboptimal branch point at a guanosine.

Virus research 20060601

Dose-responsive insulin regulation of glucose transport in human skeletal muscle.

American journal of physiology. Endocrinology and metabolism 20060601

Thermodynamic properties of enzyme-catalyzed reactions involving guanine, xanthine, and their nucleosides and nucleotides.

Biophysical chemistry 20060601

ApoE-epsilon 4-dependent association of the choline acetyltransferase gene polymorphisms (2384G>A and 1882G>A) with Alzheimer's disease.

Clinica chimica acta; international journal of clinical chemistry 20060601

In the ventral tegmental area, G-proteins mediate progesterone's actions at dopamine type 1 receptors for lordosis of rats and hamsters.

Psychopharmacology 20060601

Identification of the somatostatin receptor subtypes (sst) mediating the divergent, stimulatory/inhibitory actions of somatostatin on growth hormone secretion.

Endocrinology 20060601

SB-616234-A (1-[6-(cis-3,5-dimethylpiperazin-1-yl)-2,3-dihydro-5-methoxyindol-1-yl]-1-[2'methyl-4'-(5-methyl-1,2,3-oxadiazol-3-yl)biphenyl-4-yl]methanone hydrochloride): a novel, potent and selective 5-HT1B receptor antagonist.

Neuropharmacology 20060601

N-methylpurine DNA glycosylase and 8-oxoguanine dna glycosylase metabolize the antiviral nucleoside 2-bromo-5,6-dichloro-1-(beta-D-ribofuranosyl)benzimidazole.

Drug metabolism and disposition: the biological fate of chemicals 20060601

S-nitrosylation of cysteine 289 of the AT1 receptor decreases its binding affinity for angiotensin II.

British journal of pharmacology 20060601

Nucleobase catalysis in the hairpin ribozyme.

RNA (New York, N.Y.) 20060601

Pathogen-associated molecular patterns are growth and survival factors for human myeloma cells through Toll-like receptors.

Leukemia 20060601

Immunohistochemical study of caveolin-1 and -2 in the rat retina.

Journal of veterinary science 20060601

A phosphatidylinositol-3-kinase-dependent signal transition regulates ARF1 and ARF6 during Fcgamma receptor-mediated phagocytosis.

PLoS biology 20060601

mu opioid and CB1 cannabinoid receptor interactions: reciprocal inhibition of receptor signaling and neuritogenesis.

British journal of pharmacology 20060601

Glyceraldehyde-3-phosphate dehydrogenase regulation in Lactococcus lactis ssp. cremoris MG1363 or relA mutant at low pH.

Journal of applied microbiology 20060601

A yeast 2-hybrid analysis of human GTP cyclohydrolase I protein interactions.

Journal of neurochemistry 20060601

Inflammation and multiple myeloma: the Toll connection.

Leukemia 20060601

Molecular dissection of the mycobacterial stringent response protein Rel.

Protein science : a publication of the Protein Society 20060601

Endothelin 1 stimulates beta1Pix-dependent activation of Cdc42 through the G(salpha) pathway.

Experimental biology and medicine (Maywood, N.J.) 20060601

Involvement of endothelin in morphine tolerance in neuroblastoma (SH-SY5Y) cells.

Experimental biology and medicine (Maywood, N.J.) 20060601

Involvement of central endothelin receptors in neonatal morphine withdrawal.

Experimental biology and medicine (Maywood, N.J.) 20060601

Insights into the physiology of childbirth using transcriptomics.

PLoS medicine 20060601

Rice GTPase OsRacB: potential accessory factor in plant salt-stress signaling.

Acta biochimica et biophysica Sinica 20060601

Zinc in the treatment of acute diarrhea: current status and assessment.

Gastroenterology 20060601

Effect of oestradiol on PAMP-mediated CCL20/MIP-3 alpha production by mouse uterine epithelial cells in culture.

Immunology 20060601

Characterization of a lipid hydroperoxide-derived RNA adduct in rat intestinal epithelial cells.

Chemical research in toxicology 20060601

Nucleotide mutations in purA gene and pur operon promoter discovered in guanosine- and inosine-producing Bacillus subtilis strains.

Biotechnology letters 20060601

Toll-like receptor agonists stimulate differential functional activation and cytokine and chemokine gene expression in heterophils isolated from chickens with differential innate responses.

Microbes and infection 20060601

Improved circadian sleep-wake cycle in infants fed a day/night dissociated formula milk.

Neuro endocrinology letters 20060601

Constitutive expression of the human peroxiredoxin V gene contributes to protection of the genome from oxidative DNA lesions and to suppression of transcription of noncoding DNA.

The FEBS journal 20060601

Unusual metal specificity and structure of the group I ribozyme from Chlamydomonas reinhardtii 23S rRNA.

The FEBS journal 20060601

Biochemical and electrophysiological changes of substantia nigra pars reticulata driven by subthalamic stimulation in patients with Parkinson's disease.

The European journal of neuroscience 20060601

Valsartan in the treatment of heart attack survivors.

Vascular health and risk management 20060601

Cold virus fusion or stopping fusion cold--inhibitors of the human respiratory syncytial virus F protein.

Recent patents on anti-infective drug discovery 20060601

Inconspicuous consumption: uncovering the molecular pathways behind phagocytosis.

PLoS biology 20060601

Polymorphism of the signaling molecule c-di-GMP.

Journal of the American Chemical Society 20060531

Structure and synthesis of 6-(substituted-imidazol-1-yl)purines: versatile substrates for regiospecific alkylation and glycosylation at N9.

The Journal of organic chemistry 20060526

Histamine release, an undesired effect of thrombin inhibitors with basic character, is mediated through direct activation of G(i) proteins.

European journal of pharmacology 20060524

Dominant negative mutants of transducin-alpha that block activated receptor.

Biochemistry 20060523

Guanophostin A: Synthesis and evaluation of a high affinity agonist of the D-myo-inositol 1,4,5-trisphosphate receptor.

Chemical communications (Cambridge, England) 20060521

Efficient synthesis of 2'-C-beta-methylguanosine.

The Journal of organic chemistry 20060512

Novel OPA1 mutations identified in Japanese pedigrees with optic atrophy.

Molecular vision 20060512

The crystal structure of the apoenzyme of the iron-sulphur cluster-free hydrogenase.

Journal of molecular biology 20060505

Cannabinoid system in the budgerigar brain.

Brain research 20060504

A pyrazolato-bridged dinuclear platinum(II) complex induces only minor distortions upon DNA-binding.

Chemistry (Weinheim an der Bergstrasse, Germany) 20060503

Mutations of CB1 T210 produce active and inactive receptor forms: correlations with ligand affinity, receptor stability, and cellular localization.

Biochemistry 20060502

Quantification of oxidized RNAs in Alzheimer's disease.

Neurobiology of aging 20060501

Amnesic effect of GMP depends on its conversion to guanosine.

Neurobiology of learning and memory 20060501

Differential coupling of the P2Y1 receptor to Galpha14 and Galphaq/11 proteins during the development of the rat salivary gland.

Archives of oral biology 20060501

Loss of TRPV1-expressing sensory neurons reduces spinal mu opioid receptors but paradoxically potentiates opioid analgesia.

Journal of neurophysiology 20060501

Galanin and galanin-like peptide differentially modulate neuronal activities in rat arcuate nucleus neurons.

Journal of neurophysiology 20060501

The high throughput screening of neuropeptide FF2 receptor ligands from Korean herbal plant extracts.

Peptides 20060501

Entecavir: a new treatment option for chronic hepatitis B.

Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology 20060501

Interpretation of intramolecular stacking effect on the fluorescence intensity decay of 3-methylbenzimidazolyl(5'-5')guanosine dinucleotides using a model of lifetime distribution.

European biophysics journal : EBJ 20060501

Increased phosphodiesterase-5 expression is involved in the decreased vasodilator response to nitric oxide in cirrhotic rat livers.

Journal of hepatology 20060501

Cell and tissue responses of a range of Urotensin II analogs at cloned and native urotensin II receptors. Evidence for coupling promiscuity.

Naunyn-Schmiedeberg's archives of pharmacology 20060501

Cbfa-1 mediates nitric oxide regulation of MMP-13 in osteoblasts.

Journal of cell science 20060501

L-cysteine inhibits insulin release from the pancreatic beta-cell: possible involvement of metabolic production of hydrogen sulfide, a novel gasotransmitter.

Diabetes 20060501

Rapid and sensitive real-time polymerase chain reaction method for detection and quantification of 3243A>G mitochondrial point mutation.

The Journal of molecular diagnostics : JMD 20060501

Detection of common disease-causing mutations in mitochondrial DNA (mitochondrial encephalomyopathy, lactic acidosis with stroke-like episodes MTTL1 3243 A>G and myoclonic epilepsy associated with ragged-red fibers MTTK 8344A>G) by real-time polymerase chain reaction.

The Journal of molecular diagnostics : JMD 20060501

Synthesis and evaluation as NOP ligands of some spiro[piperidine-4,2'(1'H)-quinazolin]-4'(3'H)-ones and spiro[piperidine-4,5'(6'H)-[1,2,4]triazolo[1,5-c]quinazolines].

Chemical & pharmaceutical bulletin 20060501

Guanosine and inosine display antioxidant activity, protect DNA in vitro from oxidative damage induced by reactive oxygen species, and serve as radioprotectors in mice.

Radiation research 20060501

Airway smooth muscle prostaglandin-EP1 receptors directly modulate beta2-adrenergic receptors within a unique heterodimeric complex.

The Journal of clinical investigation 20060501

Elevated levels of urinary 8-hydroxy-2 -deoxyguanosine, lymphocytic micronuclei, and serum glutathione S-transferase in workers exposed to coke oven emissions.

Environmental health perspectives 20060501

Delivery of the malaria virulence protein PfEMP1 to the erythrocyte surface requires cholesterol-rich domains.

Eukaryotic cell 20060501

Cloning, purification and preliminary crystallographic analysis of the Bacillus subtilis GTPase YphC-GDP complex.

Acta crystallographica. Section F, Structural biology and crystallization communications 20060501

Exisulind and guanylyl cyclase C induce distinct antineoplastic signaling mechanisms in human colon cancer cells.

Molecular cancer therapeutics 20060501

Distribution of poly(A) RNA and splicing machinery elements in mature Hyacinthus orientalis L. pollen grains and pollen tubes growing in vitro.

Protoplasma 20060501

Prolonged treatment with ligands affects ligand binding to the human serotonin(1A) receptor in Chinese hamster ovary cells.

Cellular and molecular neurobiology 20060501

Beneficial effects of combined benazepril-amlodipine on cardiac nitric oxide, cGMP, and TNF-alpha production after cardiac ischemia.

Journal of cardiovascular pharmacology 20060501

Quality evaluation of Cordyceps through simultaneous determination of eleven nucleosides and bases by RP-HPLC.

Journal of separation science 20060501

Guanosine 5'-[gamma-thio]triphosphate-mediated activation of cytosol phospholipase C caused lysosomal destabilization.

The Journal of membrane biology 20060501

SB-649915, a novel, potent 5-HT1A and 5-HT1B autoreceptor antagonist and 5-HT re-uptake inhibitor in native tissue.

European journal of pharmacology 20060424

Synthesis and CB1 receptor activities of dimethylheptyl derivatives of 2-arachidonoyl glycerol (2-AG) and 2-arachidonyl glyceryl ether (2-AGE).

Bioorganic & medicinal chemistry 20060415

Assessment of a high-throughput screening methodology for the measurement of purified UCP1 uncoupling activity.

Analytical biochemistry 20060415

Nucleotide exchange via local protein unfolding--structure of Rab8 in complex with MSS4.

The EMBO journal 20060405

Supramolecular switches based on the guanine-cytosine (GC) Watson-Crick pair: effect of neutral and ionic substituents.

Chemistry (Weinheim an der Bergstrasse, Germany) 20060403

Identification and characterization of a G-protein regulatory motif in WAVE1.

FEBS letters 20060403

Heritable differences in the dopaminergic regulation of behavior in rats: relationship to D2-like receptor G-protein function.

Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20060401

Chronic pain induces anxiety with concomitant changes in opioidergic function in the amygdala.

Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20060401

Sphingosine-1-phosphate activates BKCa channels independently of G protein-coupled receptor in human endothelial cells.

American journal of physiology. Cell physiology 20060401

Involvement of calmodulin and myosin light chain kinase in activation of mTRPC5 expressed in HEK cells.

American journal of physiology. Cell physiology 20060401

Mechanisms of ligand binding to the parathyroid hormone (PTH)/PTH-related protein receptor: selectivity of a modified PTH(1-15) radioligand for GalphaS-coupled receptor conformations.

Molecular endocrinology (Baltimore, Md.) 20060401

Reaction mechanism and substrate specificity for nucleotide sugar of mammalian alpha1,6-fucosyltransferase--a large-scale preparation and characterization of recombinant human FUT8.

Glycobiology 20060401

Distribution of nociceptin and Ro64-6198 activated [35S]-GTPgammaS binding in the rat brain.

Neuropeptides 20060401

Discovery of naturally occurring splice variants of the rat histamine H3 receptor that act as dominant-negative isoforms.

Molecular pharmacology 20060401

The G12 family of G proteins as a reporter of thromboxane A2 receptor activity.

Molecular pharmacology 20060401

On the mechanism of interaction of potent surmountable and insurmountable antagonists with the prostaglandin D2 receptor CRTH2.

Molecular pharmacology 20060401

Nitric oxide, a biological double-faced janus--is this good or bad?

Histology and histopathology 20060401

Regulation of spontaneous contractile activity in the bovine epididymal duct by cyclic guanosine 5'-monophosphate-dependent pathways.

Endocrinology 20060401

Big dynorphin as a putative endogenous ligand for the kappa-opioid receptor.

Journal of neurochemistry 20060401

Mu-opioid receptors are involved in the tolerance to nicotine antinociception.

Journal of neurochemistry 20060401

Proteomic analyses of Oryza sativa mature pollen reveal novel proteins associated with pollen germination and tube growth.

Proteomics 20060401

Radioligand binding and functional responses of ligands for human recombinant adenosine A(3) receptors.

Autonomic & autacoid pharmacology 20060401

A gene involved in modifying transfer RNA is required for fungal pathogenicity and stress tolerance of Colletotrichum lagenarium.

Molecular microbiology 20060401

Role of mitochondrial superoxide dismutase in the development of diabetic retinopathy.

Investigative ophthalmology & visual science 20060401

Halothane does not inhibit the functional coupling between the beta2-adrenergic receptor and the Galphas heterotrimeric G protein.

Anesthesiology 20060401

Mucosal immunization with a urease B DNA vaccine induces innate and cellular immune responses against Helicobacter pylori.

Helicobacter 20060401

Effect of L-arginine therapy on the glomerular injury of preeclampsia: a randomized controlled trial.

Obstetrics and gynecology 20060401

Photooxidation of acyclovir with thermally generated triplet excited ketones. A comparison with type I and II photosensitizers.

Chemical & pharmaceutical bulletin 20060401

Identification and classification of conserved RNA secondary structures in the human genome.

PLoS computational biology 20060401

Evidence for a role of CaMKIV in the development of opioid analgesic tolerance.

The European journal of neuroscience 20060401

Role of protein kinase C, G-protein coupled receptors, and calcium flux during metamorphosis of the sea urchin Strongylocentrotus purpuratus.

The Biological bulletin 20060401

An innovative cell-based assay for the detection of modulators of soluble guanylate cyclase.

Assay and drug development technologies 20060401

Partial agonist properties of the antipsychotics SSR181507, aripiprazole and bifeprunox at dopamine D2 receptors: G protein activation and prolactin release.

European journal of pharmacology 20060327

Identity elements required for enzymatic formation of N2,N2-dimethylguanosine from N2-monomethylated derivative and its possible role in avoiding alternative conformations in archaeal tRNA.

Journal of molecular biology 20060324

Synthesis, structures, and electrochemistry of gold(III) ethylenediamine complexes and interactions with guanosine 5'-monophosphate.

Inorganic chemistry 20060320

Conformational changes associated with receptor-stimulated guanine nucleotide exchange in a heterotrimeric G-protein alpha-subunit: NMR analysis of GTPgammaS-bound states.

The Journal of biological chemistry 20060317

The RNA-binding PUA domain of archaeal tRNA-guanine transglycosylase is not required for archaeosine formation.

The Journal of biological chemistry 20060317

Acquisition of the wobble modification in mitochondrial tRNALeu(CUN) bearing the G12300A mutation suppresses the MELAS molecular defect.

Human molecular genetics 20060315

Increased opioid receptor binding and G protein coupling in the accumbens and ventral tegmental area of postnatal day 2 rats.

Neuroscience letters 20060313

The N terminus of GTP gamma S-activated transducin alpha-subunit interacts with the C terminus of the cGMP phosphodiesterase gamma-subunit.

The Journal of biological chemistry 20060310

Neonatal 3,4-methylenedioxymethamphetamine (MDMA) exposure alters neuronal protein kinase A activity, serotonin and dopamine content, and [35S]GTPgammaS binding in adult rats.

Brain research 20060310

N-substituted 4beta-methyl-5-(3-hydroxyphenyl)-7alpha-amidomorphans are potent, selective kappa opioid receptor antagonists.

Journal of medicinal chemistry 20060309

A comparison of entecavir and lamivudine for HBeAg-positive chronic hepatitis B.

The New England journal of medicine 20060309

Determination of antiviral nucleoside analogues AM365 and AM188 in perfusate and bile of the isolated perfused rat liver using HPLC.

Biomedical chromatography : BMC 20060301

Profile of Toll-like receptor expressions and induction of nitric oxide synthesis by Toll-like receptor agonists in chicken monocytes.

Molecular immunology 20060301

Nitrative DNA damage in inflammation and its possible role in carcinogenesis.

Nitric oxide : biology and chemistry 20060301

Genetic manipulation of two fowlpox virus late transcriptional regulatory elements influences their ability to direct expression of foreign genes.

Virus research 20060301

Differential efficacies of somatostatin receptor agonists for G-protein activation and desensitization of somatostatin receptor subtype 4-mediated responses.

The Journal of pharmacology and experimental therapeutics 20060301

Comparison of the antinociceptive response to morphine and morphine-like compounds in male and female Sprague-Dawley rats.

The Journal of pharmacology and experimental therapeutics 20060301

Nitrative stress through formation of 8-nitroguanosine: insights into microbial pathogenesis.

Nitric oxide : biology and chemistry 20060301

Leishmania amazonensis: chemotaxic and osmotaxic responses in promastigotes and their probable role in development in the phlebotomine gut.

Experimental parasitology 20060301

Design of noninflammatory synthetic siRNA mediating potent gene silencing in vivo.

Molecular therapy : the journal of the American Society of Gene Therapy 20060301

Effect of trimetazidine on the nucleotide profile in rat kidney with ischemia-reperfusion injury.

European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20060301

G protein-associated, specific membrane binding sites mediate the neuroprotective effect of dehydroepiandrosterone.

FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20060301

The basic secretagogue compound 48/80 activates G proteins indirectly via stimulation of phospholipase D-lysophosphatidic acid receptor axis and 5-HT1A receptors in rat brain sections.

British journal of pharmacology 20060301

Differential activation of G-proteins by mu-opioid receptor agonists.

British journal of pharmacology 20060301

Seasonal changes of nucleotides in mussel (Mytilus galloprovincialis) mantle tissue.

Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology 20060301

GTP drives myosin light chain 1 interaction with the class V myosin Myo2 IQ motifs via a Sec2 RabGEF-mediated pathway.

Molecular microbiology 20060301

Role of nitric oxide in the relaxation elicited by sildenafil in penile resistance arteries.

The Journal of urology 20060301

Specific functional interactions of nucleotides at key -3 and +4 positions flanking the initiation codon with components of the mammalian 48S translation initiation complex.

Genes & development 20060301

Synthesis of oligodeoxynucleotides containing a single 6alpha- or 6beta-diastereoisomer of N2-(estradiol-6-yl)-2'-deoxyguanosine.

Chemical research in toxicology 20060301

Mu-opioid receptor cellular function in the nucleus accumbens is essential for hedonically driven eating.

The European journal of neuroscience 20060301

Influence of a high carbohydrate diet on the functional activity of 5-HT1B/1D receptors on human peripheral blood lymphocytes during intense military training.

European cytokine network 20060301

Suppression of food intake and food-reinforced behavior produced by the novel CB1 receptor antagonist/inverse agonist AM 1387.

Pharmacology, biochemistry, and behavior 20060301

An efficient process for synthesis of 2'-O-methyl and 3'-O-methyl guanosine from 2-aminoadenosine using diazomethane and the catalyst stannous chloride.

Nucleosides, nucleotides & nucleic acids 20060301

An industrial process for selective synthesis of 7-methyl guanosine 5'-diphosphate: versatile synthon for synthesis of mRNA cap analogues.

Nucleosides, nucleotides & nucleic acids 20060301

Topical non-iontophoretic application of acetylcholine and nitroglycerin via a translucent patch: a new means for assessing microvascular reactivity.

The Yale journal of biology and medicine 20060301

Pharmacological manipulation of cyclic GMP levels in brain restores learning ability in animal models of hepatic encephalopathy: therapeutic implications.

Neuropsychiatric disease and treatment 20060301

Nomenclature for the human Arf family of GTP-binding proteins: ARF, ARL, and SAR proteins.

The Journal of cell biology 20060227

Differential phosphorylation of the rhodopsin cytoplasmic tail mediates the binding of arrestin and its splice variant, p44.

Biochemistry 20060221

Lipid and peptide control of phosphatidylinositol 4-kinase IIalpha activity on Golgi-endosomal Rafts.

The Journal of biological chemistry 20060217

Comparison of the in vitro efficacy of mu, delta, kappa and ORL1 receptor agonists and non-selective opioid agonists in dog brain membranes.

Brain research 20060216

[35S]GTPgammaS binding at the human dopamine D4 receptor variants hD4.2, hD4.4 and hD4.7 following stimulation by dopamine, epinephrine and norepinephrine.

European journal of pharmacology 20060215

Position-dependent repression and promotion of DQB1 intron 3 splicing by GGGG motifs.

Journal of immunology (Baltimore, Md. : 1950) 20060215

Illuminated rhodopsin is required for strong activation of retinal guanylate cyclase by guanylate cyclase-activating proteins.

Biochemistry 20060214

Guanosine 3',5'-bispyrophosphate coordinates global gene expression during glucose-lactose diauxie in Escherichia coli.

Proceedings of the National Academy of Sciences of the United States of America 20060214

No change in cortical muscarinic M2, M3 receptors or [35S]GTPgammaS binding in schizophrenia.

Life sciences 20060209

Use of probes with fluorescence indicator distributed throughout the pharmacophore to examine the peptide agonist-binding environment of the family B G protein-coupled secretin receptor.

The Journal of biological chemistry 20060203

Improved synthesis of 2'-amino-2'-deoxyguanosine and its phosphoramidite.

Bioorganic & medicinal chemistry 20060201

Identification of an achiral analogue of J-113397 as potent nociceptin/orphanin FQ receptor antagonist.

Bioorganic & medicinal chemistry 20060201

Cyclic guanosine 5'-monophosphate-dependent protein kinase II is induced by luteinizing hormone and progesterone receptor-dependent mechanisms in granulosa cells and cumulus oocyte complexes of ovulating follicles.

Molecular endocrinology (Baltimore, Md.) 20060201

A novel cannabinoid peripheral cannabinoid receptor-selective inverse agonist blocks leukocyte recruitment in vivo.

The Journal of pharmacology and experimental therapeutics 20060201

Immunomodulatory effects of Toll-like receptor-7 activation on chronic lymphocytic leukemia cells.

Leukemia 20060201

The 'allosteric modulator' SCH-202676 disrupts G protein-coupled receptor function via sulphydryl-sensitive mechanisms.

British journal of pharmacology 20060201

Agonist activity of naloxone benzoylhydrazone at recombinant and native opioid receptors.

British journal of pharmacology 20060201

Differential immune effects mediated by Toll-like receptors stimulation in precursor B-cell acute lymphoblastic leukaemia.

British journal of haematology 20060201

Sequence-specific recognition of RNA hairpins by the SAM domain of Vts1p.

Nature structural & molecular biology 20060201

Markers of oxidative stress in placental villi exposed to ethanol.

Journal of the Society for Gynecologic Investigation 20060201

A metabolic study of patients with lung cancer and hyponatremia of malignancy.

Clinical cancer research : an official journal of the American Association for Cancer Research 20060201

5-HT-stimulated [35S]guanosine-5'-O-(3-thio)triphosphate binding as an assay for functional activation of G proteins coupled with 5-HT1B receptors in rat striatal membranes.

Naunyn-Schmiedeberg's archives of pharmacology 20060201

IMP dehydrogenase inhibitor mycophenolate mofetil induces caspase-dependent apoptosis and cell cycle inhibition in multiple myeloma cells.

Molecular cancer therapeutics 20060201

Catecholaminergic activation of G-protein coupling in rat spinal cord: further evidence for the existence of dopamine and noradrenaline receptors in spinal grey and white matter.

Brain research 20060127

Phospholipase Cbeta1 modulates pain sensitivity, opioid antinociception and opioid tolerance formation.

Brain research 20060119

Natriuretic peptides, but not nitric oxide donors, elevate levels of cytosolic guanosine 3',5'-cyclic monophosphate in ependymal cells ex vivo.

Neuroscience letters 20060116

GABA(B) receptor function and subunit expression in the rat spinal cord as indicators of stress and the antinociceptive response to antidepressants.

Brain research 20060112

A unimolecular G-quadruplex that functions as a synthetic transmembrane Na+ transporter.

Journal of the American Chemical Society 20060111

Single transmembrane domain insulin-like growth factor-II/mannose-6-phosphate receptor regulates central cholinergic function by activating a G-protein-sensitive, protein kinase C-dependent pathway.

The Journal of neuroscience : the official journal of the Society for Neuroscience 20060111

Regulation of the interaction of inosine monophosphate dehydrogenase with mycophenolic Acid by GTP.

The Journal of biological chemistry 20060106

Molecular basis for nucleotide-binding specificity: role of the exocyclic amino group 'N2' in recognition by a guanylyl-ribonuclease.

Journal of molecular biology 20060106

7-Functionalized 7-deazapurine ribonucleosides related to 2-aminoadenosine, guanosine, and xanthosine: glycosylation of pyrrolo[2,3-d]pyrimidines with 1-O-acetyl-2,3,5-tri-O-benzoyl-D-ribofuranose.

The Journal of organic chemistry 20060106

Effects of the perfusion flow rate on skeletal muscle energy metabolism and a possible role of second messengers in this process.

Physiological research 20060101

Constitutively active micro opioid receptors mediate the enhanced conditioned aversive effect of naloxone in morphine-dependent mice.

Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20060101

A docking site for G protein βγ subunits on the parathyroid hormone 1 receptor supports signaling through multiple pathways.

Molecular endocrinology (Baltimore, Md.) 20060101

Purine and pyrimidine metabolism and electrocortical brain activity during hypotension in near-term lambs.

Biology of the neonate 20060101

Relationship between activating and editing functions of the adenylation domain of apo-tyrocidin synthetase 1 (apo-TY1).

Biochimie 20060101

The carboxyl terminus of the Galpha-subunit is the latch for triggered activation of heterotrimeric G proteins.

Molecular pharmacology 20060101

The reaction of water with guanosine radical cation in DNA.

Photochemistry and photobiology 20060101

A delayed ATP-elicited K+ current in freshly isolated smooth muscle cells from mouse aorta.

British journal of pharmacology 20060101

Treating HCV with ribavirin analogues and ribavirin-like molecules.

The Journal of antimicrobial chemotherapy 20060101

Radical production and DNA damage induced by carcinogenic 4-hydrazinobenzoic acid, an ingredient of mushroom Agaricus bisporus.

Free radical research 20060101

Base-pairing potential identified by in vitro selection predicts the kinked RNA backbone observed in the crystal structure of the alfalfa mosaic virus RNA-coat protein complex.

Journal of molecular recognition : JMR 20060101

Effect of long-term phosphate starvation on the levels and metabolism of purine nucleotides in suspension-cultured Catharanthus roseus cells.

Phytochemistry 20060101

Subtle but variable conformational rearrangements in the replication cycle of Sulfolobus solfataricus P2 DNA polymerase IV (Dpo4) may accommodate lesion bypass.

Protein science : a publication of the Protein Society 20060101

Hydrogen peroxide causes uncoupling of dopamine D1-like receptors from G proteins via a mechanism involving protein kinase C and G-protein-coupled receptor kinase 2.

Free radical biology & medicine 20060101

18F-FEAU as a radiotracer for herpes simplex virus thymidine kinase gene expression: in-vitro comparison with other PET tracers.

Nuclear medicine communications 20060101

New horizons for (p)ppGpp in bacterial and plant physiology.

Trends in microbiology 20060101

Azathioprine suppresses ezrin-radixin-moesin-dependent T cell-APC conjugation through inhibition of Vav guanosine exchange activity on Rac proteins.

Journal of immunology (Baltimore, Md. : 1950) 20060101

Biosynthesis of cellulose-enriched tension wood in Populus: global analysis of transcripts and metabolites identifies biochemical and developmental regulators in secondary wall biosynthesis.

The Plant journal : for cell and molecular biology 20060101

Stepwise translocation of Dpo4 polymerase during error-free bypass of an oxoG lesion.

PLoS biology 20060101

Age-related emotionality is associated with cortical delta-opioid receptor dysfunction-dependent astrogliosis.

Neuroscience 20060101

MazG -- a regulator of programmed cell death in Escherichia coli.

Molecular microbiology 20060101

Effect of vardenafil, an inhibitor of phosphodiesterase-5, on portal haemodynamics in normal and cirrhotic liver -- results of a pilot study.

Alimentary pharmacology & therapeutics 20060101

Nitroglycerin reperfusion reduces ischemia-reperfusion injury in non-heart-beating donor lungs.

The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 20060101

N2-carboxyethyl-2'-deoxyguanosine, a DNA glycation marker, in kidneys and aortas of diabetic and uremic patients.

Kidney international 20060101

The greater reactivity of estradiol-3,4-quinone vs estradiol-2,3-quinone with DNA in the formation of depurinating adducts: implications for tumor-initiating activity.

Chemical research in toxicology 20060101

Spinal nerve ligation does not alter the expression or function of GABA(B) receptors in spinal cord and dorsal root ganglia of the rat.

Neuroscience 20060101

Molecular phylogenetics and comparative modeling of HEN1, a methyltransferase involved in plant microRNA biogenesis.

BMC evolutionary biology 20060101

Efficient synthesis of [2-15N]guanosine and 2'-deoxy[2'-15N]guanosine derivatives using N-(tert-butyldimethylsilyl)[15N]phthalimide as a 15N-labeling reagent.

Nucleosides, nucleotides & nucleic acids 20060101

Purification of P-Rex1 from neutrophils and nucleotide exchange assay.

Methods in enzymology 20060101

Phosphorylation of RhoGDI by p21-activated kinase 1.

Methods in enzymology 20060101

Highly expressed proteins have an increased frequency of alanine in the second amino acid position.

BMC genomics 20060101

A method to determine RNA and DNA oxidation simultaneously by HPLC-ECD: greater RNA than DNA oxidation in rat liver after doxorubicin administration.

Biological chemistry 20060101

Macrophage migration inhibitory factor induces cell death and decreases neuronal nitric oxide expression in spinal cord neurons.

Neuroscience 20060101

Cannabinoid receptor binding to membrane homogenates and cannabinoid-stimulated [35S]GTPgammaS binding to membrane homogenates or intact cultured cells.

Methods in molecular medicine 20060101

Quantification of benzo[a]pyrene diol epoxide DNA-adducts by stable isotope dilution liquid chromatography/tandem mass spectrometry.

Rapid communications in mass spectrometry : RCM 20060101

Uneven distribution of nucleoside transporters and intracellular enzymatic degradation prevent transport of intact [14C] adenosine across the sheep choroid plexus epithelium as a monolayer in primary culture.

Cerebrospinal fluid research 20060101

Changes in ion transport in inflammatory disease.

Journal of inflammation (London, England) 20060101

Rac2 concentrations in umbilical cord neutrophils.

Biology of the neonate 20060101

Thalidomide attenuates nitric oxide mediated angiogenesis by blocking migration of endothelial cells.

BMC cell biology 20060101

Prevention and treatment of recurrent Hepatitis B after liver transplantation: the current role of nucleoside and nucleotide analogues.

Annals of clinical microbiology and antimicrobials 20060101

Synaptic depression and short-term habituation are located in the sensory part of the mammalian startle pathway.

BMC neuroscience 20060101

Improvement of bioprocess monitoring: development of novel concepts.

Microbial cell factories 20060101

Rational drug design of selective epsilon opioid receptor agonist TAN-821 and antagonist TAN-1014.

Current medicinal chemistry 20060101

Intervention of Toll-like receptor-mediated human innate immunity and inflammation by synthetic compounds and naturally occurring products.

Current medicinal chemistry 20060101

8-nitroguanine, a product of nitrative DNA damage caused by reactive nitrogen species: formation, occurrence, and implications in inflammation and carcinogenesis.

Antioxidants & redox signaling 20060101

Guanosine and inosine as natural antioxidants and radioprotectors for mice exposed to lethal doses of gamma-radiation.

Doklady. Biochemistry and biophysics 20060101

Transcriptome analysis of Deinagkistrodon acutus venomous gland focusing on cellular structure and functional aspects using expressed sequence tags.

BMC genomics 20060101

Analysis of EGF receptor interactions with the alpha subunit of the stimulatory GTP binding protein of adenylyl cyclase, Gs.

Methods in molecular biology (Clifton, N.J.) 20060101

Molecular pathopharmacology of 5-HT2C receptors and the RNA editing in the brain.

Journal of pharmacological sciences 20060101

Protection against esophageal cancer in rodents with lyophilized berries: potential mechanisms.

Nutrition and cancer 20060101

Singlet oxygen oxidation of isolated and cellular DNA: product formation and mechanistic insights.

Photochemistry and photobiology 20060101

Functional coupling of the Galpha(olf) variant XLGalpha(olf) with the human adenosine A2A receptor.

Journal of receptor and signal transduction research 20060101

Epidemiology, risk factors, and lifestyle modifications for gout.

Arthritis research & therapy 20060101

Recent developments in our understanding of the renal basis of hyperuricemia and the development of novel antihyperuricemic therapeutics.

Arthritis research & therapy 20060101

Lung epithelium as a sentinel and effector system in pneumonia--molecular mechanisms of pathogen recognition and signal transduction.

Respiratory research 20060101

P2Y2 receptor up-regulation induced by guanosine or UTP in rat brain cultured astrocytes.

International journal of immunopathology and pharmacology 20060101

In vitro binding and functional studies of Ac-RYYRIK-ol and its derivatives, novel partial agonists of the nociceptin/orphanin F/Q receptor.

Neuro-Signals 20060101

Characterization of constitutively active mutants of G protein-coupled receptors.

Methods in molecular biology (Clifton, N.J.) 20060101

Reconstitution system based on cytosol-depleted cells to study the regulation of phospholipase D.

Methods in molecular biology (Clifton, N.J.) 20060101

Does WAVE1 contain a GoLoco/GPR motif?

International journal of biological sciences 20060101

Concentration of nucleosides and related compounds in cerebral and cerebellar cortical areas and white matter of the human brain.

Cellular and molecular neurobiology 20060101

Synthesis of 2'-amino-LNA purine nucleosides.

Nucleosides, nucleotides & nucleic acids 20060101

Trimethylguanosine nucleoside inhibits cross-linking between Snurportin 1 and m3G-CAPPED U1 snRNA.

Nucleosides, nucleotides & nucleic acids 20060101

Structure of the biologically relevant G-quadruplex in the c-MYC promoter.

Nucleosides, nucleotides & nucleic acids 20060101

Consequences of low birthweight on urinary excretion of DNA markers of oxidative stress in young men.

Scandinavian journal of clinical and laboratory investigation 20060101

Nuclear import of spliceosomal snRNPs.

Canadian journal of physiology and pharmacology 20060101

Regulation of the crossbridge cycle in vascular smooth muscle by cAMP signalling.

Journal of muscle research and cell motility 20060101

Recording long-term potentiation of synaptic transmission by three-dimensional multi-electrode arrays.

BMC neuroscience 20060101

Analysis of signal transduction: formation of cAMP, cGMP, and Ins(1,4,5)P3 in vivo and in vitro.

Methods in molecular biology (Clifton, N.J.) 20060101

Global gene expression during stringent response in Corynebacterium glutamicum in presence and absence of the rel gene encoding (p)ppGpp synthase.

BMC genomics 20060101

Short G-rich oligonucleotides as a potential therapeutic for Huntington's Disease.

BMC neuroscience 20060101

Recent advances in the bcr-abl negative chronic myeloproliferative diseases.

Journal of translational medicine 20060101

New insight into the role of phosphodiesterase 3A in porcine oocyte maturation.

BMC developmental biology 20060101

TasA-tasB, a new putative toxin-antitoxin (TA) system from Bacillus thuringiensis pGI1 plasmid is a widely distributed composite mazE-doc TA system.

BMC genomics 20060101

Inhibition of hepatitis C replicon RNA synthesis by beta-D-2'-deoxy-2'-fluoro-2'-C-methylcytidine: a specific inhibitor of hepatitis C virus replication.

Antiviral chemistry & chemotherapy 20060101

The eggshell is required for meiotic fidelity, polar-body extrusion and polarization of the C. elegans embryo.

BMC biology 20060101

Generation of RNAi libraries for high-throughput screens.

Journal of biomedicine & biotechnology 20060101

Guanosine analog in the pyrido[2,3-d]pyrimidine ring system as a potential toll-like receptor agonist.

Nucleosides, nucleotides & nucleic acids 20060101

RiboSubstrates: a web application addressing the cleavage specificities of ribozymes in designated genomes.

BMC bioinformatics 20060101

methBLAST and methPrimerDB: web-tools for PCR based methylation analysis.

BMC bioinformatics 20060101

Antifibrotic actions of mycophenolic acid.

Clinical transplantation 20060101

The conserved protein kinase-A target motif in synapsin of Drosophila is effectively modified by pre-mRNA editing.

BMC neuroscience 20060101

Systematic assignment of thermodynamic constraints in metabolic network models.

BMC bioinformatics 20060101

Genetic polymorphisms of MMP1, MMP3 and MMP7 gene promoter and risk of colorectal adenoma.

BMC cancer 20060101

The pulmonary effects of intravenous adenosine in asthmatic subjects.

Respiratory research 20060101

A strategy for selective N-acylation of purine and pyrimidine bases of deoxy and ribo nucleosides.

Nucleic acids symposium series (2004) 20060101

Fluorescence detection of 8-oxoguanosine by G-clamp derivatives.

Nucleic acids symposium series (2004) 20060101

Ribonucleome analysis identified enzyme genes responsible for wybutosine synthesis.

Nucleic acids symposium series (2004) 20060101

Systematic review and meta-analysis of randomised trials and cohort studies of mycophenolate mofetil in lupus nephritis.

Arthritis research & therapy 20060101

Purine nucleoside analogs as immunosuppressive and antineoplastic agents: mechanism of action and clinical activity.

Current medicinal chemistry 20060101

Comparative analysis of hepatitis C virus phylogenies from coding and non-coding regions: the 5' untranslated region (UTR) fails to classify subtypes.

Virology journal 20060101

The release of nitric oxide from S-nitrosothiols promotes angiogenesis.

PloS one 20060101

Human coronavirus 229E encodes a single ORF4 protein between the spike and the envelope genes.

Virology journal 20060101

Array-CGH and multipoint FISH to decode complex chromosomal rearrangements.

BMC genomics 20060101

Significance of 8-oxoG in the spectrum of DNA damages caused by ionising radiation of different quality.

Radiation protection dosimetry 20060101

[Guanosine and inosine as natural geneprotectors for mice blood cells exposed to X-rays].

Radiatsionnaia biologiia, radioecologiia 20060101

Conjugates of phthalocyanines with oligonucleotides as reagents for sensitized or catalytic DNA modification.

Bioinorganic chemistry and applications 20060101

N-substituted cis-4a-(3-hydroxyphenyl)-8a-methyloctahydroisoquinolines are opioid receptor pure antagonists.

Journal of medicinal chemistry 20051229

A quadruply hydrogen bonded heterocomplex displaying high-fidelity recognition.

Journal of the American Chemical Society 20051228

Competition between glutathione and guanine for a ruthenium(II) arene anticancer complex: detection of a sulfenato intermediate.

Journal of the American Chemical Society 20051221

Differential interactions of G-proteins and adenylyl cyclase with nucleoside 5'-triphosphates, nucleoside 5'-[gamma-thio]triphosphates and nucleoside 5'-[beta,gamma-imido]triphosphates.

Biochemical pharmacology 20051219

Sequence dependence of charge transport through DNA domains.

Journal of the American Chemical Society 20051214

Transducin activation state controls its light-dependent translocation in rod photoreceptors.

The Journal of biological chemistry 20051209

Molecular characterization of the gerbil C5a receptor and identification of a transmembrane domain V amino acid that is crucial for small molecule antagonist interaction.

The Journal of biological chemistry 20051209

Identification of 9-hydroxyoctadecadienoic acid and other oxidized free fatty acids as ligands of the G protein-coupled receptor G2A.

The Journal of biological chemistry 20051209

Differential ion current activation by human 5-HT(1A) receptors in Xenopus oocytes: evidence for agonist-directed trafficking of receptor signalling.

Neuropharmacology 20051201

Two sequential phosphates 3' adjacent to the 8-oxoguanosine are crucial for lesion excision by E. coli Fpg protein and human 8-oxoguanine-DNA glycosylase.

Biochimie 20051201

Nalmefene induced elevation in serum prolactin in normal human volunteers: partial kappa opioid agonist activity?

Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20051201

Ontogeny of central melatonin receptors in tadpoles of the anuran Rana perezi: modulation of dopamine release.

Journal of comparative physiology. A, Neuroethology, sensory, neural, and behavioral physiology 20051201

Short-term plasticity of Bergmann glial cell extrasynaptic currents during parallel fiber stimulation in rat cerebellum.

Glia 20051201

Serotonin mediates learning-induced potentiation of excitability.

Journal of neurophysiology 20051201

Selective type 5 phosphodiesterase inhibition alters pulmonary hemodynamics and lung liquid production in near-term fetal lambs.

Journal of applied physiology (Bethesda, Md. : 1985) 20051201

Modulation of agonist binding to human dopamine receptor subtypes by L-prolyl-L-leucyl-glycinamide and a peptidomimetic analog.

The Journal of pharmacology and experimental therapeutics 20051201

Identification of novel mediators of NF-kappaB through genome-wide survey of monocyte adherence-induced genes.

Journal of leukocyte biology 20051201

Evidence that the plant cannabinoid Delta9-tetrahydrocannabivarin is a cannabinoid CB1 and CB2 receptor antagonist.

British journal of pharmacology 20051201

Complexation of antimony (Sb(V)) with guanosine 5'-monophosphate and guanosine 5'-diphospho-D-mannose: formation of both mono- and bis-adducts.

Journal of inorganic biochemistry 20051201

Sustained pharmacological blockade of NK1 substance P receptors causes functional desensitization of dorsal raphe 5-HT 1A autoreceptors in mice.

Journal of neurochemistry 20051201

Induction of inclusion formation and disruption of lamin A/C structure by premutation CGG-repeat RNA in human cultured neural cells.

Human molecular genetics 20051201

The structures of exocyst subunit Exo70p and the Exo84p C-terminal domains reveal a common motif.

Nature structural & molecular biology 20051201

Oxidative stress contributes to the enhanced expression of Gialpha proteins and adenylyl cyclase signaling in vascular smooth muscle cells from spontaneously hypertensive rats.

Journal of hypertension 20051201

ATP- and adenosine-induced relaxation of the smooth muscle of the pig urethra.

BJU international 20051201

Multiple interaction sites of galnon trigger its biological effects.

Neuropeptides 20051201

Rho guanosine diphosphate-dissociation inhibitor plays a negative modulatory role in glucose-stimulated insulin secretion.

Diabetes 20051201

Interruption of homologous desensitization in cyclic guanosine 3',5'-monophosphate signaling restores colon cancer cytostasis by bacterial enterotoxins.

Cancer research 20051201

Biophysical properties of voltage-gated Na+ channels in frog parathyroid cells and their modulation by cannabinoids.

The Journal of experimental biology 20051201

Guanosine triphosphatase activation occurs downstream of calcineurin in cardiac hypertrophy*.

Journal of investigative medicine : the official publication of the American Federation for Clinical Research 20051201

Quantitation of four guanine oxidation products from reaction of DNA with varying doses of peroxynitrite.

Chemical research in toxicology 20051201

3-Hydrogenkwadaphnin from Dendrostellera lessertii induces differentiation and apoptosis in HL-60 cells.

Planta medica 20051201

The development of an europium-GTP assay to quantitate chemokine antagonist interactions for CXCR4 and CCR5.

Assay and drug development technologies 20051201

[Natriuretic peptides: a new lipolytic pathway in human fat cells].

Medecine sciences : M/S 20051201

Oxidised guanidinohydantoin (Ghox) and spiroiminodihydantoin (Sp) are major products of iron- and copper-mediated 8-oxo-7,8-dihydroguanine and 8-oxo-7,8-dihydro-2'-deoxyguanosine oxidation.

Molecular bioSystems 20051201

Endogenous opioid analgesia in peripheral tissues and the clinical implications for pain control.

Therapeutics and clinical risk management 20051201

First joint Italian-German purine club meeting 'Progress in Purinergic Receptor Pharmacology and Function'.

Purinergic signalling 20051201

Isozyme-specific stimulation of phospholipase C-gamma2 by Rac GTPases.

The Journal of biological chemistry 20051125

Rapid, Wnt-induced changes in GSK3beta associations that regulate beta-catenin stabilization are mediated by Galpha proteins.

Current biology : CB 20051122

A role for the distal carboxyl tails in generating the novel pharmacology and G protein activation profile of mu and delta opioid receptor hetero-oligomers.

The Journal of biological chemistry 20051118

Species-specific identification of mycobacterial 16S rRNA PCR amplicons using smart probes.

Analytical chemistry 20051115

Heterotrimeric G-protein alpha-subunit adopts a 'preactivated' conformation when associated with betagamma-subunits.

The Journal of biological chemistry 20051111

Discovery of a gene family critical to wyosine base formation in a subset of phenylalanine-specific transfer RNAs.

The Journal of biological chemistry 20051111

Direct NMR detection of the 'invisible' alkali metal cations tightly bound to G-quadruplex structures.

Biochemical and biophysical research communications 20051111

Direct experimental observation of the effect of the base pairing on the oxidation potential of Guanine.

Journal of the American Chemical Society 20051102

Fenobam: a clinically validated nonbenzodiazepine anxiolytic is a potent, selective, and noncompetitive mGlu5 receptor antagonist with inverse agonist activity.

The Journal of pharmacology and experimental therapeutics 20051101

Expression of human 8-oxoguanine DNA glycosylase (hOGG1) in follicular lymphoma.

Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc 20051101

Characterization of a novel bivalent morphinan possessing kappa agonist and micro agonist/antagonist properties.

The Journal of pharmacology and experimental therapeutics 20051101

Molecular mechanisms involved in the asymmetric interaction between cannabinoid and opioid systems.

Psychopharmacology 20051101

3-Hydrogenkwadaphnin targets inosine 5'-monophosphate dehydrogenase and triggers post-G1 arrest apoptosis in human leukemia cell lines.

The international journal of biochemistry & cell biology 20051101

Allosteric modulation of the cannabinoid CB1 receptor.

Molecular pharmacology 20051101

Simultaneous high performance liquid chromatographic separation of purines, pyrimidines, N-acetylated amino acids, and dicarboxylic acids for the chemical diagnosis of inborn errors of metabolism.

Clinical biochemistry 20051101

Sodium valproate inhibits glucose transport and exacerbates Glut1-deficiency in vitro.

Journal of cellular biochemistry 20051101

Broad-spectrum inhibitor of viruses in the Flaviviridae family.

Antiviral research 20051101

Dopamine modulates voltage-activated potassium currents in zebrafish retinal on bipolar cells.

Journal of neuroscience research 20051101

Urinary cyclic guanosine 3',5'-monophosphate and cyclic adenosine 3',5'-monophosphate changes in spontaneous and induced onset active labor.

Acta obstetricia et gynecologica Scandinavica 20051101

Syn-full behavior by T7 DNA polymerase.

Structure (London, England : 1993) 20051101

A lysine residue in the fingers subdomain of T7 DNA polymerase modulates the miscoding potential of 8-oxo-7,8-dihydroguanosine.

Structure (London, England : 1993) 20051101

Stability and association with the cytomatrix of mitochondrial DNA in spontaneously immortalized mouse embryo fibroblasts containing or lacking the intermediate filament protein vimentin.

DNA and cell biology 20051101

Oxidative stress defense mechanisms to counter iron-promoted DNA damage in Helicobacter pylori.

Free radical research 20051101

[Effects of tamoxifen on the voltage-dependent ionic currents in mouse colonic smooth muscle cells].

The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi 20051101

[Chloroplast ppGpp synthesis system].

Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme 20051101

[High intestinal transport activity for nucleosides in cattle: a synopsis].

DTW. Deutsche tierarztliche Wochenschrift 20051101

Hepatitis C virus nonstructural protein 5A (NS5A) is an RNA-binding protein.

The Journal of biological chemistry 20051028

Apoptosis induced by nucleosides in the human hepatoma HepG2.

World journal of gastroenterology 20051028

Conformations of nucleotides bound to wild type and Y78F mutant yeast guanylate kinase: proton two-dimensional transferred NOESY measurements.

Biochemistry 20051025

A switch 3 point mutation in the alpha subunit of transducin yields a unique dominant-negative inhibitor.

The Journal of biological chemistry 20051021

The role of canonical transient receptor potential 7 in B-cell receptor-activated channels.

The Journal of biological chemistry 20051021

Requirement of 8-mercaptoguanosine as a costimulus for IL-4-dependent mu to gamma1 class switch recombination in CD38-activated B cells.

Biochemical and biophysical research communications 20051021

Optimizing control of simulated moving beds--experimental implementation.

Journal of chromatography. A 20051021

SERS studies of the adsorption of guanine derivatives on gold colloidal nanoparticles.

Physical chemistry chemical physics : PCCP 20051021

COMT Val108/158Met genotype affects the mu-opioid receptor system in the human brain: evidence from ligand-binding, G-protein activation and preproenkephalin mRNA expression.

NeuroImage 20051015

Post mortem degradation of nucleosides in the brain: comparison of human and rat brains for estimation of in vivo concentration of nucleosides.

Journal of neuroscience methods 20051015

Subchronic haloperidol increases CB(1) receptor binding and G protein coupling in discrete regions of the basal ganglia.

Journal of neuroscience research 20051015

Mechanisms of action of mycophenolate mofetil in preventing acute and chronic allograft rejection.

Transplantation 20051015

RNA challenges for computational chemists.

Biochemistry 20051011

Structural and thermodynamic features of spiroiminodihydantoin damaged DNA duplexes.

Biochemistry 20051011

Design, synthesis, and preliminary pharmacological evaluation of a set of small molecules that directly activate gi proteins.

Journal of medicinal chemistry 20051006

Ribosome dysfunction is an early event in Alzheimer's disease.

The Journal of neuroscience : the official journal of the Society for Neuroscience 20051005

Metabotropic P2Y1 receptors inhibit P2X3 receptor-channels in rat dorsal root ganglion neurons.

European journal of pharmacology 20051003

5-HT1A receptor-mediated G protein activation assessed by [35S]GTPgammaS binding in rat cerebral cortex.

European journal of pharmacology 20051003

Nucleoside transporter expression and function in cultured mouse astrocytes.

Glia 20051001

Differential effects of the 5-hydroxytryptamine (5-HT)1A receptor inverse agonists Rec 27/0224 and Rec 27/0074 on electrophysiological responses to 5-HT1A receptor activation in rat dorsal raphe nucleus and hippocampus in vitro.

The Journal of pharmacology and experimental therapeutics 20051001

Direct inhibition of substantia gelatinosa neurones in the rat spinal cord by activation of dopamine D2-like receptors.

The Journal of physiology 20051001

Chronic morphine up-regulates G alpha12 and cytoskeletal proteins in Chinese hamster ovary cells expressing the cloned mu opioid receptor.

The Journal of pharmacology and experimental therapeutics 20051001

Differential behavioral tolerance to the delta-opioid agonist SNC80 ([(+)-4-[(alphaR)-alpha-[(2S,5R)-2,5-dimethyl-4-(2-propenyl)-1-piperazinyl]-(3-methoxyphenyl)methyl]-N,N-diethylbenzamide) in Sprague-Dawley rats.

The Journal of pharmacology and experimental therapeutics 20051001

Regulation of ASAP1 by phospholipids is dependent on the interface between the PH and Arf GAP domains.

Cellular signalling 20051001

Activation and nuclear translocation of ERK1/2 by the formyl peptide receptor is regulated by G protein and is not dependent on beta-arrestin translocation or receptor endocytosis.

Cellular signalling 20051001

Synthetic oligonucleotides: AFM characterisation and electroanalytical studies.

Bioelectrochemistry (Amsterdam, Netherlands) 20051001

Biphenyl-indanones: allosteric potentiators of the metabotropic glutamate subtype 2 receptor.

Bioorganic & medicinal chemistry letters 20051001

Hypoxic-ischemic insult decreases glutamate uptake by hippocampal slices from neonatal rats: prevention by guanosine.

Experimental neurology 20051001

Synthesis and in vitro pharmacological studies of C(4) modified salvinorin A analogues.

Bioorganic & medicinal chemistry letters 20051001

Lysozyme binding to endocardial endothelium mediates myocardial depression by the nitric oxide guanosine 3',5' monophosphate pathway in sepsis.

Journal of molecular and cellular cardiology 20051001

Differential effects on [35S]GTPgammaS binding using muscarinic agonists and antagonists in the gerbil brain.

Journal of chemical neuroanatomy 20051001

Dynamics of SNARE assembly and disassembly during sperm acrosomal exocytosis.

PLoS biology 20051001

The antiviral drug ribavirin does not mimic the 7-methylguanosine moiety of the mRNA cap structure in vitro.

RNA (New York, N.Y.) 20051001

Diacylglycerol-activated Hmunc13 serves as an effector of the GTPase Rab34.

Traffic (Copenhagen, Denmark) 20051001

Atrial natriuretic peptide induces an acrosome reaction in giant panda spermatozoa and enhances their penetration of salt-stored porcine oocytes.

Theriogenology 20051001

Kinetics and crystal structure of human purine nucleoside phosphorylase in complex with 7-methyl-6-thio-guanosine.

Archives of biochemistry and biophysics 20051001

Characterization of porcine beta1- and beta2-adrenergic receptors in heart, skeletal muscle, and adipose tissue, and the identification of an atypical beta-adrenergic binding site.

Journal of animal science 20051001

Zinc-mediated inhibition of cyclic nucleotide phosphodiesterase activity and expression suppresses TNF-alpha and IL-1 beta production in monocytes by elevation of guanosine 3',5'-cyclic monophosphate.

Journal of immunology (Baltimore, Md. : 1950) 20051001

Selective phosphodiesterase 5 inhibition does not reduce propofol sedation requirements but affects speed of recovery and plasma cyclic guanosine 3',5'-monophosphate concentrations in healthy volunteers.

Anesthesia and analgesia 20051001

KKHA-761, a potent D3 receptor antagonist with high 5-HT1A receptor affinity, exhibits antipsychotic properties in animal models of schizophrenia.

Pharmacology, biochemistry, and behavior 20051001

Yersinia pseudotuberculosis spatially controls activation and misregulation of host cell Rac1.

PLoS pathogens 20051001

Hydrophilic statin suppresses vein graft intimal hyperplasia via endothelial cell-tropic Rho-kinase inhibition.

Journal of vascular surgery 20051001

Metabolism and disposition of the antiviral nucleoside analogue AM365 in the isolated perfused rat liver.

Current drug metabolism 20051001

Activation of natural killer-like YT-INDY cells by oligodeoxynucleotides and binding by homologous pattern recognition proteins.

Scandinavian journal of immunology 20051001

Kappa- and delta-opioid receptor functional activities are increased in the caudate putamen of cannabinoid CB1 receptor knockout mice.

The European journal of neuroscience 20051001

Antimicrobial drug resistance: 'Prediction is very difficult, especially about the future'.

Emerging infectious diseases 20051001

[(3)H]Alvimopan binding to the micro opioid receptor: comparative binding kinetics of opioid antagonists.

European journal of pharmacology 20050927

Allelic expression imbalance of human mu opioid receptor (OPRM1) caused by variant A118G.

The Journal of biological chemistry 20050923

Tautomers of one-electron-oxidized guanosine.

Angewandte Chemie (International ed. in English) 20050919

Giardia lamblia RNA cap guanine-N2 methyltransferase (Tgs2).

The Journal of biological chemistry 20050916

Structure-function studies on a synthetic guanosine receptor that simultaneously binds Watson-Crick and Hoogsteen sites.

The Journal of organic chemistry 20050916

Sildenafil improves alveolar growth and pulmonary hypertension in hyperoxia-induced lung injury.

American journal of respiratory and critical care medicine 20050915

Synthesis of long-chain amide analogs of the cannabinoid CB1 receptor antagonist N-(piperidinyl)-5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4-methyl-1H-pyrazole-3-carboxamide (SR141716) with unique binding selectivities and pharmacological activities.

Bioorganic & medicinal chemistry 20050915

Discovery of a potent and selective 5-ht5A receptor antagonist by high-throughput chemistry.

Bioorganic & medicinal chemistry letters 20050915

Transcriptional analysis of the cyclopropane fatty acid synthase gene of Lactococcus lactis MG1363 at low pH.

FEMS microbiology letters 20050915

Solid-state 87Rb NMR signatures for rubidium cations bound to a G-quadruplex.

Chemical communications (Cambridge, England) 20050914

Effects of statins on 3-hydroxy-3-methylglutaryl coenzyme a reductase inhibition beyond low-density lipoprotein cholesterol.

The American journal of cardiology 20050905

Interaction of calmodulin with the serotonin 5-hydroxytryptamine2A receptor. A putative regulator of G protein coupling and receptor phosphorylation by protein kinase C.

The Journal of biological chemistry 20050902

Crystal structure of M-Ras reveals a GTP-bound 'off' state conformation of Ras family small GTPases.

The Journal of biological chemistry 20050902

Kinetic analysis of steps in the repair of damaged DNA by human O6-alkylguanine-DNA alkyltransferase.

The Journal of biological chemistry 20050902

Structural evidence for a two-metal-ion mechanism of group I intron splicing.

Science (New York, N.Y.) 20050902

Novel antipsychotics activate recombinant human and native rat serotonin 5-HT1A receptors: affinity, efficacy and potential implications for treatment of schizophrenia.

The international journal of neuropsychopharmacology 20050901

Behavioral tolerance to lysergic acid diethylamide is associated with reduced serotonin-2A receptor signaling in rat cortex.

Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20050901

Guanine nucleotide exchange-independent activation of Gs protein by beta2-adrenoceptor.

Molecular pharmacology 20050901

Identification of four novel exon 5 splice variants of the mouse mu-opioid receptor gene: functional consequences of C-terminal splicing.

Molecular pharmacology 20050901

Functional complementation and the analysis of opioid receptor homodimerization.

Molecular pharmacology 20050901

The yicM (nepI) gene of Escherichia coli encodes a major facilitator superfamily protein involved in efflux of purine ribonucleosides.

FEMS microbiology letters 20050901

A new technique for the quantitative assessment of 8-oxoguanine in nuclear DNA as a marker of oxidative stress. Application to dystrophin-deficient DMD skeletal muscles.

Histochemistry and cell biology 20050901

Functional identification of catalytic metal ion binding sites within RNA.

PLoS biology 20050901

Redox metals and oxidative abnormalities in human prion diseases.

Acta neuropathologica 20050901

Isatoribine, an agonist of TLR7, reduces plasma virus concentration in chronic hepatitis C infection.

Hepatology (Baltimore, Md.) 20050901

Myocardial and coronary sinus purines as indicators of pig heart energy metabolism during reperfusion after extracorporeal circulation.

Acta physiologica Scandinavica 20050901

Hyperoxic ventilated premature baboons have increased p53, oxidant DNA damage and decreased VEGF expression.

Pediatric research 20050901

Effect of cardiopulmonary bypass and surgical intervention on the natriuretic hormone system in children.

The Journal of thoracic and cardiovascular surgery 20050901

Indirect activation of adenosine A1 receptors in cultured rat hippocampal neurons by volatile anaesthetics.

European journal of anaesthesiology 20050901

Nei deficient Escherichia coli are sensitive to chromate and accumulate the oxidized guanine lesion spiroiminodihydantoin.

Chemical research in toxicology 20050901

Mechanism of acrolein-induced vascular toxicity.

Journal of physiology and pharmacology : an official journal of the Polish Physiological Society 20050901

Poly(ADP-ribose) polymerase-1 is a novel nuclear target for cholinergic receptor signaling in the hippocampus.

Journal of physiology and pharmacology : an official journal of the Polish Physiological Society 20050901

Expression of inhibitory G proteins in adenomatous thyroid glands obtained from hyperthyroid cats.

American journal of veterinary research 20050901

[Identification of 5 constituents of the aqueous extract of Isatis indigotica by HPLC-MS2].

Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials 20050901

G-quartet-induced nanoparticle assembly.

Journal of the American Chemical Society 20050824

Regulation of human recombinant P2X3 receptors by ecto-protein kinase C.

The Journal of neuroscience : the official journal of the Society for Neuroscience 20050824

Reduced kappa-opioid activity in a rat model of cholestasis.

European journal of pharmacology 20050822

Opioid receptor-like 1 (NOP) receptors in the rat dorsal raphe nucleus: evidence for localization on serotoninergic neurons and functional adaptation after 5,7-dihydroxytryptamine lesion.

Journal of neuroscience research 20050815

PHI-1 induced enhancement of myosin phosphorylation in chicken smooth muscle.

FEBS letters 20050815

WTH3, which encodes a small G protein, is differentially regulated in multidrug-resistant and sensitive MCF7 cells.

Cancer research 20050815

On-line hyphenation of quantum cascade laser and capillary electrophoresis.

Journal of chromatography. A 20050812

Oral human brain natriuretic peptide activates cyclic guanosine 3',5'-monophosphate and decreases mean arterial pressure.

Circulation 20050809

Distinct functional properties of native somatostatin receptor subtype 5 compared with subtype 2 in the regulation of ACTH release by corticotroph tumor cells.

American journal of physiology. Endocrinology and metabolism 20050801

Phenoxybenzamine and benextramine, but not 4-diphenylacetoxy-N-[2-chloroethyl]piperidine hydrochloride, display irreversible noncompetitive antagonism at G protein-coupled receptors.

The Journal of pharmacology and experimental therapeutics 20050801

Mu opioid receptor coupling to Gi/o proteins increases during postnatal development in rat brain.

The Journal of pharmacology and experimental therapeutics 20050801

The endocannabinoid noladin ether acts as a full agonist at human CB2 cannabinoid receptors.

The Journal of pharmacology and experimental therapeutics 20050801

Andrograpanin, a compound isolated from anti-inflammatory traditional Chinese medicine Andrographis paniculata, enhances chemokine SDF-1alpha-induced leukocytes chemotaxis.

Journal of cellular biochemistry 20050801

Effect of nitric oxide-cGMP-dependent protein kinase activation on advanced glycation end-product-induced proliferation in renal fibroblasts.

Journal of the American Society of Nephrology : JASN 20050801

Intriguing mass spectrometric behavior of guanosine under low energy collision-induced dissociation: H2O adduct formation and gas-phase reactions in the collision cell.

Journal of the American Society for Mass Spectrometry 20050801

Hydantoin derivative formation from oxidation of 7,8-dihydro-8-oxo-2'-deoxyguanosine (8-oxodG) and incorporation of 14C-labeled 8-oxodG into the DNA of human breast cancer cells.

Bioorganic & medicinal chemistry letters 20050801

Neutrophil dysfunction in guanosine 3',5'-cyclic monophosphate-dependent protein kinase I-deficient mice.

Journal of immunology (Baltimore, Md. : 1950) 20050801

Ribavirin is not a functional mimic of the 7-methyl guanosine mRNA cap.

RNA (New York, N.Y.) 20050801

Anesthetics inhibit membrane receptor coupling to the Gq/11 heterotrimeric G protein in airway smooth muscle.

Anesthesiology 20050801

Guanosine enhances glutamate transport capacity in brain cortical slices.

Cellular and molecular neurobiology 20050801

Structural-functional relationships between terminal deoxynucleotidyltransferase and 5'-triphosphates of nucleoside analogs.

Biochemistry. Biokhimiia 20050801

Agonistic properties of cannabidiol at 5-HT1a receptors.

Neurochemical research 20050801

Mycophenolic acid inhibits syncytium formation accompanied by reduction of gp120 expression.

The Journal of antibiotics 20050801

Structure of a class II TrmH tRNA-modifying enzyme from Aquifex aeolicus.

Acta crystallographica. Section F, Structural biology and crystallization communications 20050801

The cytotoxic and anti-proliferative effects of 3-hydrogenkwadaphnin in K562 and jurkat cells is reduced by guanosine.

Journal of biochemistry and molecular biology 20050731

Precursors of chicken flavor. I. Determination of some flavor precursors in chicken muscle.

Journal of agricultural and food chemistry 20050727

Functional regulation of the opposing (p)ppGpp synthetase/hydrolase activities of RelMtb from Mycobacterium tuberculosis.

Biochemistry 20050726

Mechanisms of mu opioid receptor/G-protein desensitization in brain by chronic heroin administration.

Life sciences 20050722

Interleukin-1beta induces death in chondrocyte-like ATDC5 cells through mitochondrial dysfunction and energy depletion in a reactive nitrogen and oxygen species-dependent manner.

The Biochemical journal 20050715

Nitric oxide inhibits IFN-alpha production of human plasmacytoid dendritic cells partly via a guanosine 3',5'-cyclic monophosphate-dependent pathway.

Journal of immunology (Baltimore, Md. : 1950) 20050715

Cross-talk between adenosine and the oxatriazole derivative GEA 3175 in platelets.

European journal of pharmacology 20050711

In vitro profile of the antidepressant candidate OPC-14523 at rat and human 5-HT1A receptors.

European journal of pharmacology 20050711

The broadly selective human Na+/nucleoside cotransporter (hCNT3) exhibits novel cation-coupled nucleoside transport characteristics.

The Journal of biological chemistry 20050708

2.0 A crystal structure of human ARL5-GDP3'P, a novel member of the small GTP-binding proteins.

Biochemical and biophysical research communications 20050708

Urinary nucleosides as biological markers for patients with colorectal cancer.

World journal of gastroenterology 20050707

Lack of G protein-coupled sigma receptors in rat brain membranes: receptor-mediated high-affinity GTPase activity and [35S]GTPgammaS binding studies.

Journal of neural transmission (Vienna, Austria : 1996) 20050701

Cadmium down-regulates human OGG1 through suppression of Sp1 activity.

The Journal of biological chemistry 20050701

G protein-dependent pharmacology of histamine H3 receptor ligands: evidence for heterogeneous active state receptor conformations.

The Journal of pharmacology and experimental therapeutics 20050701

A novel monothiol glutaredoxin (Grx4) from Escherichia coli can serve as a substrate for thioredoxin reductase.

The Journal of biological chemistry 20050701

Identification of WIN55212-3 as a competitive neutral antagonist of the human cannabinoid CB2 receptor.

British journal of pharmacology 20050701

Effects of an intense training on functional activity of 5-HT(1B) receptors in human peripheral blood lymphocytes.

Neuroscience letters 20050701

Binding properties of dipropyltryptamine at the human 5-HT1a receptor.

Pharmacology 20050701

Long-term depression in rat CA1-subicular synapses depends on the G-protein coupled mACh receptors.

Neuroscience research 20050701

Antihyperalgesic properties of the cannabinoid CT-3 in chronic neuropathic and inflammatory pain states in the rat.

Pain 20050701

Synthesis and biological studies of nociceptin derivatives containing the DTPA chelating group for further labeling with therapeutic radionuclides.

Peptides 20050701

Characterization of an ecto-ATPase activity in Cryptococcus neoformans.

FEMS yeast research 20050701

TYRA-2 (F01E11.5): a Caenorhabditis elegans tyramine receptor expressed in the MC and NSM pharyngeal neurons.

Journal of neurochemistry 20050701

NO-cGMP signaling molecules in cells of the rat molar dentin-pulp complex.

Journal of dental research 20050701

A single active-site region for a group II intron.

Nature structural & molecular biology 20050701

Structure of human PNP complexed with ligands.

Acta crystallographica. Section D, Biological crystallography 20050701

Effect of chronic gestational treatment with caffeine or theophylline on Group I metabotropic glutamate receptors in maternal and fetal brain.

Journal of neurochemistry 20050701

Guanine-specific oxidation of double-stranded DNA by Cr(VI) and ascorbic acid forms spiroiminodihydantoin and 8-oxo-2'-deoxyguanosine.

Chemical research in toxicology 20050701

Autoradiographic mapping of dopamine-D2/D3 receptor stimulated [35S]GTPgammaS binding in the human brain.

The European journal of neuroscience 20050701

Adenosine and purine nucleosides prevent the disruption of mitochondrial transmembrane potential by peroxynitrite in rat primary astrocytes.

Archives of pharmacal research 20050701

Pharmacokinetics and metabolism of acriflavine in rats following intravenous or intramuscular administration of AG60, a mixture of acriflavine and guanosine, a potential antitumour agent.

Xenobiotica; the fate of foreign compounds in biological systems 20050701

Reduction of ribonucleosides to 2'-deoxyribonucleosides.

Current protocols in nucleic acid chemistry 20050701

Distribution and abundance of metabotropic glutamate receptor subtype 2 in rat brain revealed by [3H]LY354740 binding in vitro and quantitative radioautography: correlation with the sites of synthesis, expression, and agonist stimulation of [35S]GTPgammas binding.

The Journal of comparative neurology 20050620

Clathrin-dependent and clathrin-independent retrieval of synaptic vesicles in retinal bipolar cells.

Neuron 20050616

Impaired base excision repair and accumulation of oxidative base lesions in CD4+ T cells of HIV-infected patients.

Blood 20050615

Expression of SphK1 impairs degranulation and motility of RBL-2H3 mast cells by desensitizing S1P receptors.

Blood 20050615

The synthesis of substituted bipiperidine amide compounds as CCR3 ligands: antagonists versus agonists.

Bioorganic & medicinal chemistry letters 20050615

Time-resolved resonance Raman observation of the 2-fluorenylnitrenium ion reaction with guanosine to form a C8 intermediate.

Journal of the American Chemical Society 20050615

Novel molecular drug carrier: encapsulation of oxaliplatin in cucurbit[7]uril and its effects on stability and reactivity of the drug.

Organic & biomolecular chemistry 20050607

Ribosomal RNA in Alzheimer disease is oxidized by bound redox-active iron.

The Journal of biological chemistry 20050603

Abnormalities in uridine homeostatic regulation and pyrimidine nucleotide metabolism as a consequence of the deletion of the uridine phosphorylase gene.

The Journal of biological chemistry 20050603

Fancy bioisosteres: metallocene-derived G-protein-coupled receptor ligands with subnanomolar binding affinity and novel selectivity profiles.

Journal of medicinal chemistry 20050602

Locating counterions in guanosine quadruplexes: a contrast-variation neutron diffraction experiment in condensed hexagonal phase.

The journal of physical chemistry. B 20050602

Activation of BK channels in GH3 cells by a c-PLA2-dependent G-protein signaling pathway.

Journal of neurophysiology 20050601

Angiotensin II attenuates synaptic GABA release and excites paraventricular-rostral ventrolateral medulla output neurons.

The Journal of pharmacology and experimental therapeutics 20050601

In vivo characterization of 6beta-naltrexol, an opioid ligand with less inverse agonist activity compared with naltrexone and naloxone in opioid-dependent mice.

The Journal of pharmacology and experimental therapeutics 20050601

Pharmacological characterization of CXC chemokine receptor 3 ligands and a small molecule antagonist.

The Journal of pharmacology and experimental therapeutics 20050601

sigma Receptor activation blocks potassium channels and depresses neuroexcitability in rat intracardiac neurons.

The Journal of pharmacology and experimental therapeutics 20050601

An algorithm for identification of bacterial selenocysteine insertion sequence elements and selenoprotein genes.

Bioinformatics (Oxford, England) 20050601

Molecular dynamics simulation of clustered DNA damage sites containing 8-oxoguanine and abasic site.

Journal of computational chemistry 20050601

Effects of mycophenolic acid on endothelial cells.

International immunopharmacology 20050601

Purine nucleoside-mediated protection of chemical hypoxia-induced neuronal injuries involves p42/44 MAPK activation.

Neurochemistry international 20050601

A three-stemmed mRNA pseudoknot in the SARS coronavirus frameshift signal.

PLoS biology 20050601

Non-lesional vitiliginous melanocytes are not characterized by an increased proneness to nitric oxide-induced apoptosis.

Experimental dermatology 20050601

Effects of HIV Q151M-associated multi-drug resistance mutations on the activities of (-)-beta-D-1',3'-dioxolan guanine.

Antiviral research 20050601

Identification of the main oxidation products of 8-methoxy-2'-deoxyguanosine by singlet molecular oxygen.

Free radical biology & medicine 20050601

Photoinactivation of Escherichia coli using porphyrin derivatives with different number of cationic charges.

FEMS immunology and medical microbiology 20050601

Angiotensin II-evoked enhanced expression of RGS2 attenuates Gi-mediated adenylyl cyclase signaling in A10 cells.

Cardiovascular research 20050601

Determination of mercaptopurine and its four metabolites by large-volume sample stacking with polarity switching in capillary electrophoresis.

Electrophoresis 20050601

G protein-coupled galanin receptor distribution in the rat central nervous system.

Neuropeptides 20050601

Effects of central galanin administration on muscarinic cholinergic and galanin receptor G protein coupling.

Neuropeptides 20050601

Expression, purification, crystallization and preliminary X-ray analysis of a nucleoside kinase from the hyperthermophile Methanocaldococcus jannaschii.

Acta crystallographica. Section F, Structural biology and crystallization communications 20050601

Responses of the ciliates Tetrahymena and Paramecium to external ATP and GTP.

Purinergic signalling 20050601

Guanosine stimulates neurite outgrowth in PC12 cells via activation of heme oxygenase and cyclic GMP.

Purinergic signalling 20050601

Structure-activity relationships of dinucleotides: Potent and selective agonists of P2Y receptors.

Purinergic signalling 20050601

Computational study of IAG-nucleoside hydrolase: determination of the preferred ground state conformation and the role of active site residues.

Biochemistry 20050531

Model for general acid-base catalysis by the hammerhead ribozyme: pH-activity relationships of G8 and G12 variants at the putative active site.

Biochemistry 20050531

Encephalitozoon cuniculi mRNA cap (guanine N-7) methyltransferase: methyl acceptor specificity, inhibition BY S-adenosylmethionine analogs, and structure-guided mutational analysis.

The Journal of biological chemistry 20050527

Insights into microtubule nucleation from the crystal structure of human gamma-tubulin.

Nature 20050526

Purification and characterization of RihC, a xanthosine-inosine-uridine-adenosine-preferring hydrolase from Salmonella enterica serovar Typhimurium.

Biochimica et biophysica acta 20050525

Identification and characterization of rel promoter element of Mycobacterium tuberculosis.

Gene 20050523

Identification of MrgX2 as a human G-protein-coupled receptor for proadrenomedullin N-terminal peptides.

Biochemical and biophysical research communications 20050520

Up-regulation of GABA(B) receptors by chronic administration of the GABA(B) receptor antagonist SCH 50,911.

European journal of pharmacology 20050516

Sequence-structure-function relationships of a tRNA (m7G46) methyltransferase studied by homology modeling and site-directed mutagenesis.

Proteins 20050515

Rapid activation of JNK and p38 by glucocorticoids in primary cultured hippocampal cells.

Journal of neuroscience research 20050515

Stimulation of neuropeptide Y-mediated calcium responses in human SMS-KAN neuroblastoma cells endogenously expressing Y2 receptors by co-expression of chimeric G proteins.

Biochemical pharmacology 20050515

A highly stable quadruply hydrogen-bonded heterocomplex useful for supramolecular polymer blends.

Journal of the American Chemical Society 20050511

Promiscuous catalysis by the tetrahymena group I ribozyme.

Journal of the American Chemical Society 20050504

3-(2-Ethoxy-4-{4-[3-hydroxy-2-methyl-4-(3-methylbutanoyl)phenoxy]butoxy}phenyl)propanoic acid: a brain penetrant allosteric potentiator at the metabotropic glutamate receptor 2 (mGluR2).

Bioorganic & medicinal chemistry letters 20050502

Time-dependent changes in receptor/G-protein coupling in rat brain following chronic monoamine transporter blockade.

The Journal of pharmacology and experimental therapeutics 20050501

Characterization and comparison of recombinant human and rat TRPV1 receptors: effects of exo- and endocannabinoids.

British journal of anaesthesia 20050501

Orientational dynamics and dye-DNA interactions in a dye-labeled DNA aptamer.

Biophysical journal 20050501

Mechanisms of inverse agonist action at D2 dopamine receptors.

British journal of pharmacology 20050501

A combinatorial code for splicing silencing: UAGG and GGGG motifs.

PLoS biology 20050501

Binding and functional properties of the novel somatostatin analogue KE 108 at native mouse somatostatin receptors.

Neuropharmacology 20050501

Allosteric modulation of adenosine A1 receptor coupling to G-proteins in brain.

Journal of neurochemistry 20050501

Inhibitors of TLR-9 act on multiple cell subsets in mouse and man in vitro and prevent death in vivo from systemic inflammation.

Journal of immunology (Baltimore, Md. : 1950) 20050501

Stromal cell-derived factor-1alpha directly modulates voltage-dependent currents of the action potential in mammalian neuronal cells.

Journal of neurochemistry 20050501

Ras/ERK signalling in cannabinoid tolerance: from behaviour to cellular aspects.

Journal of neurochemistry 20050501

Single-molecule diffusion measurements of H-Ras at the plasma membrane of live cells reveal microdomain localization upon activation.

Journal of cell science 20050501

Vascular relaxation by the methanol extract of Sorbus cortex via NO-cGMP pathway.

Biological & pharmaceutical bulletin 20050501

Roles of Brucella abortus SpoT in morphological differentiation and intramacrophagic replication.

Microbiology (Reading, England) 20050501

Trazodone and its active metabolite m-chlorophenylpiperazine as partial agonists at 5-HT1A receptors assessed by [35S]GTPgammaS binding.

Journal of psychopharmacology (Oxford, England) 20050501

Detailed pharmacological characterization of 5-HT1A-receptor-mediated [35S]GTP gamma S binding in rat hippocampal membranes.

Journal of pharmacological sciences 20050501

ROCKs as therapeutic targets in cardiovascular diseases.

Expert review of cardiovascular therapy 20050501

The multidrug resistance protein 5 (ABCC5) confers resistance to 5-fluorouracil and transports its monophosphorylated metabolites.

Molecular cancer therapeutics 20050501

Purine nucleosides stimulate Na/K ATPase, and prolong survival in hemorrhagic shock.

The Journal of trauma 20050501

Contractile properties of the cultured vascular smooth muscle cells: the crucial role played by RhoA in the regulation of contractility.

Circulation research 20050429

Spiroiminodihydantoin lesions derived from guanine oxidation: structures, energetics, and functional implications.

Biochemistry 20050426

Functional characterization of novel human and mouse equilibrative nucleoside transporters (hENT3 and mENT3) located in intracellular membranes.

The Journal of biological chemistry 20050422

Escherichia coli purine nucleoside phosphorylase II, the product of the xapA gene.

Journal of molecular biology 20050422

Group III metabotropic glutamate receptors and exocytosed protons inhibit L-type calcium currents in cones but not in rods.

The Journal of neuroscience : the official journal of the Society for Neuroscience 20050420

31P NMR and genetic analysis establish hinT as the only Escherchia coli purine nucleoside phosphoramidase and as essential for growth under high salt conditions.

The Journal of biological chemistry 20050415

LdARL-1 His-tagged recombinant protein: purification by immobilized metal affinity expanded bed adsorption.

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20050415

Constitutively active G-protein-gated inwardly rectifying K+ channels in dendrites of hippocampal CA1 pyramidal neurons.

The Journal of neuroscience : the official journal of the Society for Neuroscience 20050413

Evidence for the involvement of cytosolic 5'-nucleotidase (cN-II) in the synthesis of guanine nucleotides from xanthosine.

The Journal of biological chemistry 20050408

Protein and RNA dynamics play key roles in determining the specific recognition of GU-rich polyadenylation regulatory elements by human Cstf-64 protein.

Journal of molecular biology 20050408

Selective modulation of neuronal nicotinic acetylcholine receptor channel subunits by Go-protein subunits.

The Journal of neuroscience : the official journal of the Society for Neuroscience 20050406

Yeast-like mRNA capping apparatus in Giardia lamblia.

The Journal of biological chemistry 20050401

Inverse agonism and neutral antagonism at wild-type and constitutively active mutant delta opioid receptors.

The Journal of pharmacology and experimental therapeutics 20050401

Pharmacological properties of ABT-239 [4-(2-{2-[(2R)-2-Methylpyrrolidinyl]ethyl}-benzofuran-5-yl)benzonitrile]: I. Potent and selective histamine H3 receptor antagonist with drug-like properties.

The Journal of pharmacology and experimental therapeutics 20050401

Visible light exposure induces VEGF gene expression through activation of retinoic acid receptor-alpha in retinoblastoma Y79 cells.

American journal of physiology. Cell physiology 20050401

A highly conserved glycine within linker I and the extreme C terminus of G protein alpha subunits interact cooperatively in switching G protein-coupled receptor-to-effector specificity.

The Journal of pharmacology and experimental therapeutics 20050401

Suramin disrupts receptor-G protein coupling by blocking association of G protein alpha and betagamma subunits.

The Journal of pharmacology and experimental therapeutics 20050401

Lipid rafts control signaling of type-1 cannabinoid receptors in neuronal cells. Implications for anandamide-induced apoptosis.

The Journal of biological chemistry 20050401

G protein-coupled receptor kinase regulates dopamine D3 receptor signaling by modulating the stability of a receptor-filamin-beta-arrestin complex. A case of autoreceptor regulation.

The Journal of biological chemistry 20050401

Effects of temperature on 2-[125I]-iodomelatonin binding to melatonin receptors in the neural retina of the frog Rana perezi.

Journal of pineal research 20050401

Functional recovery in aged and young rats after embolic stroke: treatment with a phosphodiesterase type 5 inhibitor.

Stroke 20050401

A cell-based cGMP assay useful for ultra-high-throughput screening and identification of modulators of the nitric oxide/cGMP pathway.

Analytical biochemistry 20050401

M opsin phosphorylation in intact mammalian retinas.

Journal of neurochemistry 20050401

Relationship between urinary cGMP excretion and serum total cholesterol levels in a general population.

Atherosclerosis 20050401

Identification and characterization of a functional, alternatively spliced Toll-like receptor 7 (TLR7) and genomic disruption of TLR8 in chickens.

Immunology 20050401

Various members of the Toll-like receptor family contribute to the innate immune response of human epidermal keratinocytes.

Immunology 20050401

Opioids inhibit purinergic nociceptors in the sensory neurons and fibres of rat via a G protein-dependent mechanism.

Neuropharmacology 20050401

Plasma L-arginine and metabolites of nitric oxide synthase in patients with left-to-right shunt after intracardiac repair.

Chest 20050401

A pentylenetetrazole-induced generalized seizure in early life enhances the efficacy of muscarinic receptor coupling to G-protein in hippocampus and neocortex of adult rat.

The European journal of neuroscience 20050401

G-protein coupled activation of potassium channels by endogenous neuropeptides in snail neurons.

The European journal of neuroscience 20050401

In vivo quinolinic acid increases synaptosomal glutamate release in rats: reversal by guanosine.

Neurochemical research 20050401

[The functional change in the 5-HT1A receptor induced by stress and the role of the 5-HT1A receptor in neuroprotection].

Nihon shinkei seishin yakurigaku zasshi = Japanese journal of psychopharmacology 20050401

Arrangement of mRNA 3' of the A site codon on the human 80S ribosome.

RNA biology 20050401

Nitric oxide-dependent allosteric inhibitory role of a second nucleotide binding site in soluble guanylyl cyclase.

The Journal of biological chemistry 20050325

Electrochemical studies of guanosine in DMF and detection of its radical cation in a scanning electrochemical microscopy nanogap experiment.

Journal of the American Chemical Society 20050323

Photocrosslinking detects a compact, active structure of the hammerhead ribozyme.

Biochemistry 20050322

Translation initiation factor (eIF) 4B affects the rates of binding of the mRNA m7G cap analogue to wheat germ eIFiso4F and eIFiso4F.PABP.

Biochemistry 20050322

A mutant of eukaryotic protein synthesis initiation factor eIF4E(K119A) has an increased binding affinity for both m7G cap analogues and eIF4G peptides.

Biochemistry 20050322

Roles of conserved amino acid sequence motifs in the SpoU (TrmH) RNA methyltransferase family.

The Journal of biological chemistry 20050318

A mitotic septin scaffold required for Mammalian chromosome congression and segregation.

Science (New York, N.Y.) 20050318

Development of a mechanism-based assay for tissue transglutaminase--results of a high-throughput screen and discovery of inhibitors.

Analytical biochemistry 20050315

Composition and sequence-dependent binding of RNA to the nucleocapsid protein of Moloney murine leukemia virus.

Biochemistry 20050315

Major effect of pyrrolic N-benzylation in norbinaltorphimine, the selective kappa-opioid receptor antagonist.

Journal of medicinal chemistry 20050310

A 'locked-on,' constitutively active mutant of the adenosine A1 receptor.

European journal of pharmacology 20050307

Neurochemical evaluation of the novel 5-HT1A receptor partial agonist/serotonin reuptake inhibitor, vilazodone.

European journal of pharmacology 20050307

Periplakin interferes with G protein activation by the melanin-concentrating hormone receptor-1 by binding to the proximal segment of the receptor C-terminal tail.

The Journal of biological chemistry 20050304

Real-time detection of basal and stimulated G protein GTPase activity using fluorescent GTP analogues.

The Journal of biological chemistry 20050304

GMP synthetase stimulates histone H2B deubiquitylation by the epigenetic silencer USP7.

Molecular cell 20050304

[(pF)Phe4,Arg14,Lys15]N/OFQ-NH2 (UFP-102), a highly potent and selective agonist of the nociceptin/orphanin FQ receptor.

The Journal of pharmacology and experimental therapeutics 20050301

Nonsteroidal anti-inflammatory drugs inhibit a Fyn-dependent pathway coupled to Rac and stress kinase activation in TCR signaling.

Blood 20050301

Residues Met89 and Ser160 in the human equilibrative nucleoside transporter 1 affect its affinity for adenosine, guanosine, S6-(4-nitrobenzyl)-mercaptopurine riboside, and dipyridamole.

Molecular pharmacology 20050301

Comparison of peptidic and nonpeptidic delta-opioid agonists on guanosine 5'-O-(3-[35S]thio)triphosphate ([35S]GTPgammaS) binding in brain slices from Sprague-Dawley rats.

The Journal of pharmacology and experimental therapeutics 20050301

Role of the C terminus in neuropeptide Y Y1 receptor desensitization and internalization.

Molecular pharmacology 20050301

Functional characterization of Galphao signaling through G protein-regulated inducer of neurite outgrowth 1.

Molecular pharmacology 20050301

Evidence for the functional expression and pharmacological characterization of adenine receptors in native cells and tissues.

Molecular pharmacology 20050301

Quantitative assessment of glucose transport in human skeletal muscle: dynamic positron emission tomography imaging of [O-methyl-11C]3-O-methyl-D-glucose.

The Journal of clinical endocrinology and metabolism 20050301

Identification and characterization of purine nucleoside transporters from Crithidia fasciculata.

Molecular and biochemical parasitology 20050301

Model platinum nucleobase and nucleoside complexes and antitumor activity: X-ray crystal structure of [PtIV(trans-1R,2R-diaminocyclohexane)trans-(acetate)2(9-ethylguanine)Cl]NO3.H2O.

Journal of inorganic biochemistry 20050301

Putting the brakes on cardiac hypertrophy: exploiting the NO-cGMP counter-regulatory system.

Hypertension (Dallas, Tex. : 1979) 20050301

Elevated levels of endocannabinoids and CB1 receptor-mediated G-protein signaling in the prefrontal cortex of alcoholic suicide victims.

Biological psychiatry 20050301

Vascular dysfunction in patients with chronic arsenosis can be reversed by reduction of arsenic exposure.

Environmental health perspectives 20050301

Transcriptional response of Rickettsia conorii exposed to temperature variation and stress starvation.

Research in microbiology 20050301

Role of progesterone signaling in the regulation of G-protein levels in female chronic constipation.

Gastroenterology 20050301

[Quantitative analysis of the nucleosides in Cordyceps sinensis with capillary zone electrophoresis].

Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20050301

Effects of dopamine, SKF-38393 and R(-)-NPA on ATP-activated currents in rat DRG neurons.

Canadian journal of physiology and pharmacology 20050301

[3H]LY334370, a novel radioligand for the 5-HT1F receptor. I. In vitro characterization of binding properties.

Naunyn-Schmiedeberg's archives of pharmacology 20050301

P2X7 receptor stimulation of membrane internalization in a thyrocyte cell line.

The Journal of membrane biology 20050301

[Simultaneous determination of 7-methylguanosine and mitomycin C by capillary electrophoresis with amperometric detection].

Se pu = Chinese journal of chromatography 20050301

Methods for the detection of antioxidants which prevent age related diseases: a critical review with particular emphasis on human intervention studies.

Journal of physiology and pharmacology : an official journal of the Polish Physiological Society 20050301

Role of cholesterol in ligand binding and G-protein coupling of serotonin1A receptors solubilized from bovine hippocampus.

Biochemical and biophysical research communications 20050225

Mechanisms mediating the biologic activity of synthetic proline, glycine, and hydroxyproline polypeptides in human neutrophils.

Mediators of inflammation 20050224

BU74, a complex oripavine derivative with potent kappa opioid receptor agonism and delayed opioid antagonism.

European journal of pharmacology 20050221

Oxidation of guanosine derivatives by a platinum(IV) complex: internal electron transfer through cyclization.

Journal of the American Chemical Society 20050216

Phosphodiester cleavage of guanylyl-(3',3')-(2'-amino-2'-deoxyuridine): rate acceleration by the 2'-amino function.

Journal of the American Chemical Society 20050216

Inhibition of phospholipase C-independent exocytotic responses in rat peritoneal mast cells by U73122.

Regulatory peptides 20050215

Neuronal nitric oxide modulates morphine antinociceptive tolerance by enhancing constitutive activity of the mu-opioid receptor.

Biochemical pharmacology 20050215

1,2,4-Benzothiadiazine derivatives as alpha1 and 5-HT1A receptor ligands.

Bioorganic & medicinal chemistry letters 20050215

Stable isotope labeling-mass spectrometry analysis of methyl- and pyridyloxobutyl-guanine adducts of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone in p53-derived DNA sequences.

Biochemistry 20050215

Identification of CD19 and CD20 peptides for induction of antigen-specific CTLs against B-cell malignancies.

Clinical cancer research : an official journal of the American Association for Cancer Research 20050215

Specificity and mechanism of RNA cap guanine-N2 methyltransferase (Tgs1).

The Journal of biological chemistry 20050211

Regulation of cap-dependent translation by eIF4E inhibitory proteins.

Nature 20050203

Chemo-enzymatic synthesis of 2'-O-methoxyethyl ribonucleosides using a phosphodiesterase from Serratia marcescens.

Applied microbiology and biotechnology 20050201

Endogenous regulator of g protein signaling proteins reduce {mu}-opioid receptor desensitization and down-regulation and adenylyl cyclase tolerance in C6 cells.

The Journal of pharmacology and experimental therapeutics 20050201

Anticataleptic properties of alpha2 adrenergic antagonists in the crossed leg position and bar tests: differential mediation by 5-HT1A receptor activation.

Psychopharmacology 20050201

Ca2+-independent hypoxic vasorelaxation in porcine coronary artery.

The Journal of physiology 20050201

Actin polymerization in the equatorial and postacrosomal regions of guinea pig spermatozoa during the acrosome reaction is regulated by G proteins.

Molecular reproduction and development 20050201

Dynamics and stability of GCAA tetraloops with 2-aminopurine and purine substitutions.

Journal of biomolecular structure & dynamics 20050201

Stimulation of G-proteins in human control and Alzheimer's disease brain by FAD mutants of APP(714-723): implication of oxidative mechanisms.

Journal of neuroscience research 20050201

Time-course of mitochondrial gene expressions in mice brains: implications for mitochondrial dysfunction, oxidative damage, and cytochrome c in aging.

Journal of neurochemistry 20050201

Stereoselective synthesis of 9-beta-d-arabianofuranosyl guanine and 2-amino-9-(beta-d-arabianofuranosyl)purine.

Bioorganic & medicinal chemistry letters 20050201

Triaryl bis-sulfones as a new class of cannabinoid CB2 receptor inhibitors: identification of a lead and initial SAR studies.

Bioorganic & medicinal chemistry letters 20050201

Nitric oxide-cyclic GMP contributes to abnormal activation of Na+-K+-ATPase in the aorta from rats with endotoxic shock.

Shock (Augusta, Ga.) 20050201

Chronic inhibition of cyclic GMP phosphodiesterase 5A prevents and reverses cardiac hypertrophy.

Nature medicine 20050201

The role of G proteins in the activity and ethanol modulation of glycine-induced currents in rat neurons freshly isolated from the ventral tegmental area.

Brain research 20050201

Formation of conjugate adducts in the reactions of malonaldehyde-acetaldehyde and malonaldehyde-formaldehyde with guanosine.

Chemical research in toxicology 20050201

A competitive ELISA detecting 7-methylguanosine adduct induced by N-nitrosodimethylamine exposure.

Human & experimental toxicology 20050201

Succinate enhances the cyclic guanosine monophosphate-altered intestinal motility in the rat.

The Journal of parasitology 20050201

Genetic analysis and functional characterization of polymorphisms in the human concentrative nucleoside transporter, CNT2.

Pharmacogenetics and genomics 20050201

Nesiritide in cardiovascular anesthesia.

Current opinion in anaesthesiology 20050201

Copper and zinc inhibit Galphas function: a nucleotide-free state of Galphas induced by Cu2+ and Zn2+.

The Journal of biological chemistry 20050128

Atomic force microscopy study of the structural effects induced by echinomycin binding to DNA.

Journal of molecular biology 20050128

Crystal water dynamics of guanosine dihydrate: analysis of atomic displacement parameters, time profile of hydrogen-bonding probability, and translocation of water by MD simulation.

The journal of physical chemistry. B 20050127

Demonstration of an alternative mechanism for G-to-G cross-link formation.

Journal of the American Chemical Society 20050126

Antiviral function of APOBEC3G can be dissociated from cytidine deaminase activity.

Current biology : CB 20050126

Molecular recognition in a trans excision-splicing ribozyme: non-Watson-Crick base pairs at the 5' splice site and omegaG at the 3' splice site can play a role in determining the binding register of reaction substrates.

Biochemistry 20050125

Evaluation of the 17-kDa prenyl-binding protein as a regulatory protein for phototransduction in retinal photoreceptors.

The Journal of biological chemistry 20050114

Distinct molecular mechanisms for agonist peptide binding to types A and B cholecystokinin receptors demonstrated using fluorescence spectroscopy.

The Journal of biological chemistry 20050114

How flexible are fleximer nucleobases? A computational study.

The journal of physical chemistry. A 20050113

Nanocrystal-based bioelectronic coding of single nucleotide polymorphisms.

Journal of the American Chemical Society 20050112

Studies on the mechanism of the photo-induced DNA damage in the presence of acridizinium salts-involvement of singlet oxygen and an unusual source for hydroxyl radicals.

Journal of the American Chemical Society 20050112

Polo-like kinases in the nervous system.

Oncogene 20050110

Vesicle endocytosis requires dynamin-dependent GTP hydrolysis at a fast CNS synapse.

Science (New York, N.Y.) 20050107

[Cyclic GMP as a biomarker for cardiovascular disease and cancer].

Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke 20050106

Measurement of serum pralidoxime methylsulfate (Contrathion) by high-performance liquid chromatography with electrochemical detection.

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20050105

Structure-activity relationships for 1-alkyl-3-(1-naphthoyl)indoles at the cannabinoid CB(1) and CB(2) receptors: steric and electronic effects of naphthoyl substituents. New highly selective CB(2) receptor agonists.

Bioorganic & medicinal chemistry 20050103

Tau modifiers as therapeutic targets for Alzheimer's disease.

Biochimica et biophysica acta 20050103

Identification and characterisation of a novel splice variant of the human CB1 receptor.

FEBS letters 20050103

Recognition of the oxidized lesions spiroiminodihydantoin and guanidinohydantoin in DNA by the mammalian base excision repair glycosylases NEIL1 and NEIL2.

DNA repair 20050102

Involvement of ryanodine receptors in muscarinic receptor-mediated membrane current oscillation in urinary bladder smooth muscle.

American journal of physiology. Cell physiology 20050101

Activation of an alpha2A-adrenoceptor-Galphao1 fusion protein dynamically regulates the palmitoylation status of the G protein but not of the receptor.

The Biochemical journal 20050101

Comparison of pharmacological activities of three distinct kappa ligands (Salvinorin A, TRK-820 and 3FLB) on kappa opioid receptors in vitro and their antipruritic and antinociceptive activities in vivo.

The Journal of pharmacology and experimental therapeutics 20050101

A Gbetagamma stimulated adenylyl cyclase is involved in Xenopus laevis oocyte maturation.

Journal of cellular physiology 20050101

Conserved residues F316 and G476 in the concentrative nucleoside transporter 1 (hCNT1) affect guanosine sensitivity and membrane expression, respectively.

American journal of physiology. Cell physiology 20050101

Reciprocal regulation of agonist and inverse agonist signaling efficacy upon short-term treatment of the human delta-opioid receptor with an inverse agonist.

Molecular pharmacology 20050101

Phosphatidylethanolamine enhances rhodopsin photoactivation and transducin binding in a solid supported lipid bilayer as determined using plasmon-waveguide resonance spectroscopy.

Biophysical journal 20050101

Increased D1 dopamine receptor signaling in levodopa-induced dyskinesia.

Annals of neurology 20050101

Nitric oxide-mediated regulation of connexin43 expression and gap junctional intercellular communication in mesangial cells.

Journal of the American Society of Nephrology : JASN 20050101

Effects of chronic administered guanosine on behavioral parameters and brain glutamate uptake in rats.

Journal of neuroscience research 20050101

Differential regulation of atrial natriuretic peptide- and adrenergic receptor-dependent lipolytic pathways in human adipose tissue.

Metabolism: clinical and experimental 20050101

Crystal structure of a phage Twort group I ribozyme-product complex.

Nature structural & molecular biology 20050101

Fast gas-phase hydrogen/deuterium exchange observed for a DNA G-quadruplex.

Rapid communications in mass spectrometry : RCM 20050101

Protective effect of adenosine and purine nucleos(t)ides against the death by hydrogen peroxide and glucose deprivation in rat primary astrocytes.

Neuroscience research 20050101

Autoradiographic characterisation of [35S]GTPgammaS binding stimulation mediated by 5-HT1B receptor in postmortem human brain.

Neuropharmacology 20050101

Effects of long-term biogenic amine transporter blockade on receptor/G-protein coupling in rat brain.

Neuropharmacology 20050101

Heart failure increases protein expression and enzymatic activity of heme oxygenase-1 in the lung.

Cardiovascular research 20050101

Taxonomic distribution and quantitative analysis of free purine and pyrimidine nucleosides in snake venoms.

Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology 20050101

The presence of a Leu-Gly-Asn repeat-enriched protein (LGN), a putative binding partner of transducin, in ROD photoreceptors.

Investigative ophthalmology & visual science 20050101

Oxidative nucleotide damage and superoxide dismutase expression in the brains of xeroderma pigmentosum group A and Cockayne syndrome.

Brain & development 20050101

Allosteric modulation of GABA(B) receptor function in human frontal cortex.

Neurochemistry international 20050101

The structure of a rigorously conserved RNA element within the SARS virus genome.

PLoS biology 20050101

Vasodilatation produced by orientin and its mechanism study.

Biological & pharmaceutical bulletin 20050101

[Natriuretic peptides: a new lipolytic pathway in human fat cells].

Medecine sciences : M/S 20050101

Mycophenolate mofetil modulates adhesion receptors of the beta1 integrin family on tumor cells: impact on tumor recurrence and malignancy.

BMC cancer 20050101

Acute impairment of contractile responses by 17beta-estradiol is cAMP and protein kinase G dependent in vascular smooth muscle cells of the porcine coronary arteries.

British journal of pharmacology 20050101

Terbutaline increases the cervical resistance of the pregnant rat in vitro.

Naunyn-Schmiedeberg's archives of pharmacology 20050101

Fish somatostatin sst3 receptor: comparison of radioligand and GTPgammaS binding, adenylate cyclase and phospholipase C activities reveals different agonist-dependent pharmacological signatures.

Autonomic & autacoid pharmacology 20050101

Deciphering structure and topology of conserved COG2042 orphan proteins.

BMC structural biology 20050101

Hypothesized deficiency of guanine-based purines may contribute to abnormalities of neurodevelopment, neuromodulation, and neurotransmission in Lesch-Nyhan syndrome.

Clinical neuropharmacology 20050101

Protein domains and architectural innovation in plant-associated Proteobacteria.

BMC genomics 20050101

Intracerebroventricular guanine-based purines protect against seizures induced by quinolinic acid in mice.

Neurochemical research 20050101

Mice have a transcribed L-threonine aldolase/GLY1 gene, but the human GLY1 gene is a non-processed pseudogene.

BMC genomics 20050101

Investigation of multiple binding sites on ribonuclease A using nano-electrospray ionization mass spectrometry.

Rapid communications in mass spectrometry : RCM 20050101

Crystal structure of THEP1 from the hyperthermophile Aquifex aeolicus: a variation of the RecA fold.

BMC structural biology 20050101

Identification and characterization of Iporin as a novel interaction partner for rab1.

BMC cell biology 20050101

Enhanced striatal opioid receptor-mediated G-protein activation in L-DOPA-treated dyskinetic monkeys.

Neuroscience 20050101

Mechanisms of action of mycophenolate mofetil.

Lupus 20050101

[Phorbol 12-myristate 13-acetate inhibits apoptosis in erythroleukemia K562 cells induced by some nucleosides].

Ontogenez 20050101

17Beta-estradiol modulates hMT1 melatonin receptor function.

Neuroendocrinology 20050101

The microbial selenoproteome of the Sargasso Sea.

Genome biology 20050101

S-nitrosothiols modulate G protein-coupled receptor signaling in a reversible and highly receptor-specific manner.

BMC cell biology 20050101

Pharmacological characterization of human kappa/mu opioid receptor chimeras that retain high affinity for dynorphin A.

Current topics in medicinal chemistry 20050101

Guanylic nucleotide starvation affects Saccharomyces cerevisiae mother-daughter separation and may be a signal for entry into quiescence.

BMC cell biology 20050101

Effects of mycophenolate mofetil on key pattern of coronary restenosis: a cascade of in vitro and ex vivo models.

BMC cardiovascular disorders 20050101

Nerve-induced release of nitric oxide from the rabbit corpus cavernosum is modulated by cyclic guanosine 3',5'-monophosphate.

Neuroscience 20050101

Identification and characterization of six new alternatively spliced variants of the human mu opioid receptor gene, Oprm.

Neuroscience 20050101

Expression and function of Toll-like receptors in chicken heterophils.

Developmental and comparative immunology 20050101

Inhibition of the cloned delayed rectifier K+ channels, Kv1.5 and Kv3.1, by riluzole.

Neuroscience 20050101

ATP-binding cassette (ABC) transporters in normal and pathological lung.

Respiratory research 20050101

Action of neuropeptide Y on nociceptive transmission in substantia gelatinosa of the adult rat spinal dorsal horn.

Neuroscience 20050101

Guanine-nucleotide exchange on ribosome-bound elongation factor G initiates the translocation of tRNAs.

Journal of biology 20050101

Cygnets: in vivo characterization of novel cGMP indicators and in vivo imaging of intracellular cGMP.

Methods in molecular biology (Clifton, N.J.) 20050101

High-throughput screening of phosphodiesterase activity in living cells.

Methods in molecular biology (Clifton, N.J.) 20050101

Assessment of phosphodiesterase isozyme contribution in cell and tissue extracts.

Methods in molecular biology (Clifton, N.J.) 20050101

Localization of cyclic guanosine 3',5'-monophosphate-hydrolyzing phosphodiesterase type 9 in rat brain by nonradioactive in situ hydridization.

Methods in molecular biology (Clifton, N.J.) 20050101

Cyclic guanosine 5'-monophosphate binding to regulatory GAF domains of photoreceptor phosphodiesterase.

Methods in molecular biology (Clifton, N.J.) 20050101

Radiolabeled ligand binding to the catalytic or allosteric sites of PDE5 and PDE11.

Methods in molecular biology (Clifton, N.J.) 20050101

Analysis of dimerization determinants of PDE6 catalytic subunits.

Methods in molecular biology (Clifton, N.J.) 20050101

Interactions between catalytic and inhibitory subunits of PDE6.

Methods in molecular biology (Clifton, N.J.) 20050101

Purification, reconstitution on lipid vesicles, and assays of PDE6 and its activator G protein, transducin.

Methods in molecular biology (Clifton, N.J.) 20050101

[Template location on the human ribosome: environment of the mRNA nucleotide adjacent to the A-site codon on the 3'-side].

Bioorganicheskaia khimiia 20050101

Photosensitive signal transduction induces membrane hyperpolarization in Paramecium bursaria.

Photochemistry and photobiology 20050101

A computational approach for identifying pathogenicity islands in prokaryotic genomes.

BMC bioinformatics 20050101

Macrophages and cytokines in the early defence against herpes simplex virus.

Virology journal 20050101

Ultra-low-dose naloxone suppresses opioid tolerance, dependence and associated changes in mu opioid receptor-G protein coupling and Gbetagamma signaling.

Neuroscience 20050101

Cell biology of diabetic kidney disease.

Nephron. Experimental nephrology 20050101

Retrons, msDNA, and the bacterial genome.

Cytogenetic and genome research 20050101

Long-term therapy of interferon-alpha induced pulmonary arterial hypertension with different PDE-5 inhibitors: a case report.

Cardiovascular ultrasound 20050101

Intracellularly truncated human alpha2B-adrenoceptors: stable and functional GPCRs for structural studies.

Journal of receptor and signal transduction research 20050101

Physicochemical modulation of agonist-induced [35s]GTPgammaS binding: implications for coexistence of multiple functional conformations of dopamine D1-like receptors.

Journal of receptor and signal transduction research 20050101

Calcium alginate microencapsulation of ovarian follicles impacts FSH delivery and follicle morphology.

Reproductive biology and endocrinology : RB&E 20050101

Identification of moaA3 gene in patient isolates of Mycobacterium tuberculosis in Kerala, which is absent in M. tuberculosis H37Rv and H37Ra.

BMC infectious diseases 20050101

Molecular mechanisms of autoimmunity triggered by microbial infection.

Arthritis research & therapy 20050101

Human Lsg1 defines a family of essential GTPases that correlates with the evolution of compartmentalization.

BMC biology 20050101

Alzheimer's disease related peptides affected cholinergic receptor mediated poly(ADP-ribose) polymerase activity in the hippocampus.

Folia neuropathologica 20050101

The diagnosis and therapy of brain tumours.

Folia neuropathologica 20050101

Kinetic properties of Cellulomonas sp. purine nucleoside phosphorylase with typical and non-typical substrates: implications for the reaction mechanism.

Nucleosides, nucleotides & nucleic acids 20050101

Synthesis and enzymatic characterization of methylene analogs of adenosine 5'-tetraphosphate (P4A).

Nucleosides, nucleotides & nucleic acids 20050101

Novel dinucleoside 5',5'-triphosphate cap analogues. Synthesis and affinity for murine translation factor eIF4E.

Nucleosides, nucleotides & nucleic acids 20050101

Synthesis of 5-aza-7-deazaguanine nucleoside derivatives as potential anti-flavivirus agents.

Nucleosides, nucleotides & nucleic acids 20050101

Design of highly efficient and selective transfer reaction of nitrosyl group to dc and d(M)C resulting in specific deamination.

Nucleosides, nucleotides & nucleic acids 20050101

Bis(tBuSATE) phosphotriester prodrugs of 8-azaguanosine and 6-methylpurine riboside; bis(pom) phosphotriester prodrugs of 2'-deoxy-4'-thioadenosine and its corresponding 9alpha anomer.

Nucleosides, nucleotides & nucleic acids 20050101

7-deazapurin-2,6-diamine and 7-deazaguanine: synthesis and property of 7-substituted nucleosides and oligonucleotides.

Nucleosides, nucleotides & nucleic acids 20050101

A cautionary note on the use of the 31P NMR spectroscopy in stereochemical correlation analysis.

Nucleosides, nucleotides & nucleic acids 20050101

Synthesis study of 3'-alpha-fluoro-2',3'-dideoxyguanosine.

Nucleosides, nucleotides & nucleic acids 20050101

A new approach to oligonucleotide N3'-->P5' phosphoramidate building blocks.

Nucleosides, nucleotides & nucleic acids 20050101

Studies of the intermediary metabolism in cultured cells of the insect Spodoptera frugiperda using 13C- or 15N-labelled tracers.

BMC biochemistry 20050101

Formalin injection causes a coordinated spinal cord CO/NO-cGMP signaling system response.

Molecular pain 20050101

Characterization of 954 bovine full-CDS cDNA sequences.

BMC genomics 20050101

Phosphodiesterase 3 inhibition and cough in elderly asthmatics.

Cough (London, England) 20050101

A general method for nested RT-PCR amplification and sequencing the complete HCV genotype 1 open reading frame.

Virology journal 20050101

[Positioning of mRNA 3' of the a site bound codon on the human 80S ribosome].

Molekuliarnaia biologiia 20050101

Modulation of adenylyl cyclase activity in young and adult rat brain cortex. Identification of suramin as a direct inhibitor of adenylyl cyclase.

Journal of cellular and molecular medicine 20050101

[Specific arginine mediated RNA recognition].

Postepy biochemii 20050101

Microinjection as a tool to explore small GTPase function.

Methods in enzymology 20050101

In vitro assays of Arf1 interaction with GGA proteins.

Methods in enzymology 20050101

Assays and properties of arfaptin 2 binding to Rac1 and ADP-ribosylation factors (Arfs).

Methods in enzymology 20050101

A novel imidazole nucleoside containing a diaminodihydro-S-triazine as a substituent: inhibitory activity against the West Nile virus NTPase/helicase.

Nucleosides, nucleotides & nucleic acids 20050101

Opioid receptor binding characteristics and structure-activity studies of novel tetrapeptides in the TIPP (Tyr-Tic-Phe-Phe) series.

Neuro-Signals 20050101

Hypomodification of transfer RNA in cancer with respect to queuosine.

RNA biology 20050101

NMR spectroscopic analyses of functional nucleic acids-metal interaction and their solution structure analyses.

Nucleic acids symposium series (2004) 20050101

Synthesis of purin-2-yl carboxylate from O6-methylguanosine.

Nucleic acids symposium series (2004) 20050101

Structural change of tRNA (Gm18) methyltransferase by binding of methyl donor analogues.

Nucleic acids symposium series (2004) 20050101

Substitutions in the Reverse Transcriptase and Protease Genes of HIV-1 Subtype B in Untreated Individuals and Patients Treated With Antiretroviral Drugs.

Journal of the International AIDS Society 20050101

Galpha12 directly interacts with PP2A: evidence FOR Galpha12-stimulated PP2A phosphatase activity and dephosphorylation of microtubule-associated protein, tau.

The Journal of biological chemistry 20041231

The nuclear 16-kD protein methylation increases in the early period of liver regeneration in a hepatectomized rat.

Experimental & molecular medicine 20041231

A rational utilization of high-throughput screening affords selective, orally bioavailable 1-benzyl-3-carboxyazetidine sphingosine-1-phosphate-1 receptor agonists.

Journal of medicinal chemistry 20041230

Characterization of 5-hydroxy-8-oxo-7,8-dihydroguanosine in the photosensitized oxidation of 8-oxo-7,8-dihydroguanosine and its rearrangement to spiroiminodihydantoin.

Journal of the American Chemical Society 20041229

Improved detection limit for a direct determination of 8-hydroxy-2'-deoxyguanosine in untreated urine samples by capillary electrophoresis with optical detection.

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20041225

N-retinylidene-phosphatidylethanolamine is the preferred retinoid substrate for the photoreceptor-specific ABC transporter ABCA4 (ABCR).

The Journal of biological chemistry 20041224

Functional characterization of rhodopsin monomers and dimers in detergents.

The Journal of biological chemistry 20041224

Selective 226Ra2+ ionophores provided by self-assembly of guanosine and isoguanosine derivatives.

Journal of the American Chemical Society 20041222

Intra- and intercellular variations in the repair efficiency of O6-methylguanine, and their contribution to kinetic complexity.

Mutation research 20041221

Induction of A:T to G:C transition mutations by 5-(2-chloroethyl)-2'-deoxyuridine (CEDU), an antiviral pyrimidine nucleoside analogue, in the bone marrow of Muta Mouse.

Mutation research 20041221

Using diffusion NMR to characterize guanosine self-association: insights into structure and mechanism.

Chemistry (Weinheim an der Bergstrasse, Germany) 20041217

Differentiation of human prostate cancer PC-3 cells induced by inhibitors of inosine 5'-monophosphate dehydrogenase.

Cancer research 20041215

Monitoring HSVtk suicide gene therapy: the role of [(18)F]FHPG membrane transport.

British journal of cancer 20041213

ADP-ribosylation factor 1-independent protein sorting and export from the trans-Golgi network.

The Journal of biological chemistry 20041210

Promoting vibrations in human purine nucleoside phosphorylase. A molecular dynamics and hybrid quantum mechanical/molecular mechanical study.

Journal of the American Chemical Society 20041208

A cyclic peptide mimicking the third intracellular loop of the V2 vasopressin receptor inhibits signaling through its interaction with receptor dimer and G protein.

The Journal of biological chemistry 20041203

Uncoupling of GPCR and RhoA-induced Ca2+-sensitization of chicken amnion smooth muscle lacking CPI-17.

FEBS letters 20041203

Orexin (hypocretin) effects on constitutively active inward rectifier K+ channels in cultured nucleus basalis neurons.

Journal of neurophysiology 20041201

Signaling and ligand binding by recombinant neuromedin U receptors: evidence for dual coupling to Galphaq/11 and Galphai and an irreversible ligand-receptor interaction.

Molecular pharmacology 20041201

Mechanisms of agonist action at D2 dopamine receptors.

Molecular pharmacology 20041201

A molecular code for splicing silencing: configurations of guanosine-rich motifs.

Biochemical Society transactions 20041201

Synthesis and biological evaluation of 5R- and 5S-methyl substituted D- and L-configuration 1,3-dioxolane nucleoside analogs.

Bioorganic & medicinal chemistry 20041201

Widespread A-to-I RNA editing of Alu-containing mRNAs in the human transcriptome.

PLoS biology 20041201

A survey of RNA editing in human brain.

Genome research 20041201

JNJ16259685, a highly potent, selective and systemically active mGlu1 receptor antagonist.

Neuropharmacology 20041201

Inhibition of phosphodiesterase 2 increases neuronal cGMP, synaptic plasticity and memory performance.

Neuropharmacology 20041201

Regulation of A2B adenosine receptor functioning by tumour necrosis factor a in human astroglial cells.

Journal of neurochemistry 20041201

Proteasome inhibition increases DNA and RNA oxidation in astrocyte and neuron cultures.

Journal of neurochemistry 20041201

Montmorillonite, oligonucleotides, RNA and origin of life.

Origins of life and evolution of the biosphere : the journal of the International Society for the Study of the Origin of Life 20041201

A new synthetic approach of N-(4-amino-2-methylquinolin-6-yl)-2-(4-ethylphenoxymethyl)benzamide (JTC-801) and its analogues and their pharmacological evaluation as nociceptin receptor (NOP) antagonists.

European journal of medicinal chemistry 20041201

Mycophenolic acid inhibits platelet-derived growth factor-induced reactive oxygen species and mitogen-activated protein kinase activation in rat vascular smooth muscle cells.

American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20041201

Inhaled adenosine and guanosine on airway resistance in normal and asthmatic subjects. 1983.

British journal of clinical pharmacology 20041201

A calcium channel blocker, benidipine, improves cell membrane fluidity in human subjects via a nitric oxide-dependent mechanism. An electron paramagnetic resonance investigation.

American journal of hypertension 20041201

Chromatographic separation of nucleosides using a cross-linked xylose isomerase crystal stationary phase.

Journal of separation science 20041201

P2Y receptors and pain transmission.

Purinergic signalling 20041201

DNA . RNA heteroduplex containing 8-oxo-7,8-dihydroguanosine: base pairing, structures, and thermodynamic stability.

Journal of biochemistry and molecular biology 20041130

Identification and separation of PCR products based on their GC content by denaturing high-performance liquid chromatography.

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20041125

Poly-guanosine strings improve cellular uptake and stimulatory activity of phosphodiester CpG oligonucleotides in human leukocytes.

Vaccine 20041125

Irsogladine, an anti-ulcer drug, suppresses superoxide production by inhibiting phosphodiesterase type 4 in human neutrophils.

Life sciences 20041119

Pontine and basal forebrain cholinergic interaction: implications for sleep and breathing.

Respiratory physiology & neurobiology 20041115

Electrochemical sensing of the behaviour of oligonucleotide lipoplexes at charged interfaces.

Biosensors & bioelectronics 20041115

RhoA activates purified phospholipase C-epsilon by a guanine nucleotide-dependent mechanism.

The Journal of biological chemistry 20041112

Structural mimicry in class A G protein-coupled receptor rotamer toggle switches: the importance of the F3.36(201)/W6.48(357) interaction in cannabinoid CB1 receptor activation.

The Journal of biological chemistry 20041112

A novel Galphaq/11-selective inhibitor.

The Journal of biological chemistry 20041112

Caveolae localize protein kinase A signaling to arterial ATP-sensitive potassium channels.

Circulation research 20041112

Folding thermodynamics and kinetics of YNMG RNA hairpins: specific incorporation of 8-bromoguanosine leads to stabilization by enhancement of the folding rate.

Biochemistry 20041109

Human ribosomal protein S3 interacts with DNA base excision repair proteins hAPE/Ref-1 and hOGG1.

Biochemistry 20041109

The RGS14 GoLoco domain discriminates among Galphai isoforms.

The Journal of biological chemistry 20041105

Analysis of platinum adducts with DNA nucleotides and nucleosides by capillary electrophoresis coupled to ESI-MS: indications of guanosine 5'-monophosphate O6-N7 chelation.

Chembiochem : a European journal of chemical biology 20041105

Structure of the Tetrahymena ribozyme: base triple sandwich and metal ion at the active site.

Molecular cell 20041105

Simultaneous determination of six main nucleosides and bases in natural and cultured Cordyceps by capillary electrophoresis.

Journal of chromatography. A 20041105

Mu and delta opioid-stimulated [35S]GTP gamma S binding in brain and spinal cord of polyarthritic rats.

European journal of pharmacology 20041103

Transcription activities at 8-oxoG lesions in DNA.

DNA repair 20041102

Layer variations of long-term depression in rat visual cortex.

Journal of neurophysiology 20041101

Oxidative DNA damage and DNA repair enzyme expression are inversely related in murine models of fatty liver disease.

American journal of physiology. Gastrointestinal and liver physiology 20041101

Genomic organization of mouse orexin receptors: characterization of two novel tissue-specific splice variants.

Molecular endocrinology (Baltimore, Md.) 20041101

Dopamine recruits D1A receptors to Na-K-ATPase-rich caveolar plasma membranes in rat renal proximal tubules.

American journal of physiology. Renal physiology 20041101

Gialpha3 protein-coupled dopamine D3 receptor-mediated inhibition of renal NHE3 activity in SHR proximal tubular cells is a PLC-PKC-mediated event.

American journal of physiology. Renal physiology 20041101

The serine repeat antigen (SERA) gene family phylogeny in Plasmodium: the impact of GC content and reconciliation of gene and species trees.

Molecular biology and evolution 20041101

Cyclic GMP transporters.

Neurochemistry international 20041101

Metabolic regulation of ATP breakdown and of adenosine production in rat brain extracts.

The international journal of biochemistry & cell biology 20041101

TRPC5 activation kinetics are modulated by the scaffolding protein ezrin/radixin/moesin-binding phosphoprotein-50 (EBP50).

Journal of cellular physiology 20041101

Anabolism of amdoxovir: phosphorylation of dioxolane guanosine and its 5'-phosphates by mammalian phosphotransferases.

Biochemical pharmacology 20041101

G protein activation and cyclic AMP modulation by naloxone benzoylhydrazone in distinct layers of rat olfactory bulb.

British journal of pharmacology 20041101

Multiple actions of extracellular ATP and adenosine on calcium currents mediated by various purinoceptors in neurons of nucleus tractus solitarius.

Neuroscience research 20041101

Hetero-oligomers of alpha2A-adrenergic and mu-opioid receptors do not lead to transactivation of G-proteins or altered endocytosis profiles.

Biochemical Society transactions 20041101

Homocysteine activates NADH/NADPH oxidase through ceramide-stimulated Rac GTPase activity in rat mesangial cells.

Kidney international 20041101

His452Tyr polymorphism in the human 5-HT2A receptor destabilizes the signaling conformation.

Molecular pharmacology 20041101

Conservation of capa peptide-induced nitric oxide signalling in Diptera.

The Journal of experimental biology 20041101

Alternative substrates for wild-type and L109A E. coli CTP synthases: kinetic evidence for a constricted ammonia tunnel.

European journal of biochemistry 20041101

Uroguanylin and guanylin peptides: pharmacology and experimental therapeutics.

Pharmacology & therapeutics 20041101

Identification of three new alternatively spliced variants of the rat mu opioid receptor gene: dissociation of affinity and efficacy.

Journal of neurochemistry 20041101

Potentiation of 5-HT3 receptor function by the activation of coexistent 5-HT2 receptors in trigeminal ganglion neurons of rats.

Neuropharmacology 20041101

The influence of G protein subtype on agonist action at D2 dopamine receptors.

Neuropharmacology 20041101

Mass spectrometric identification of 4-hydroxy-2,5-dioxo-imidazolidine-4-carboxylic acid during oxidation of 8-oxoguanosine by peroxynitrite and KHSO5/CoCl2.

Chemical research in toxicology 20041101

Spiroiminodihydantoin and guanidinohydantoin are the dominant products of 8-oxoguanosine oxidation at low fluxes of peroxynitrite: mechanistic studies with 18O.

Chemical research in toxicology 20041101

Plasminogen activator inhibitor-1 plasma level increases with age in subjects with the 4G allele at position -675 in the promoter region.

Thrombosis and haemostasis 20041101

Allelic isoforms of the H+/nucleoside co-transporter (CaCNT) from Candida albicans reveal separate high- and low-affinity transport systems for nucleosides.

Yeast (Chichester, England) 20041101

Distinction of water-soluble constituents between natural and cultured Cordyceps by capillary electrophoresis.

Phytomedicine : international journal of phytotherapy and phytopharmacology 20041101

An enzyme-linked immunosorbent assay for the rapid quantification of intracellular and extracellular guanosine 3',5'-cyclic monophosphate in cultured glial cells.

Neurochemical research 20041101

A novel combination of opiates and endothelin antagonists to manage pain without any tolerance development.

Journal of cardiovascular pharmacology 20041101

Role of endothelin in neonatal morphine tolerance.

Journal of cardiovascular pharmacology 20041101

TDAG8 is a proton-sensing and psychosine-sensitive G-protein-coupled receptor.

The Journal of biological chemistry 20041029

Solid-state 23Na NMR determination of the number and coordination of sodium cations bound to Oxytricha nova telomere repeat d(G4T4G4).

Biochemical and biophysical research communications 20041029

Thermodynamics of mRNA 5' cap binding by eukaryotic translation initiation factor eIF4E.

Biochemistry 20041026

Selectivity, cooperativity, and reciprocity in the interactions between the delta-opioid receptor, its ligands, and G-proteins.

The Journal of biological chemistry 20041022

Cephamycin C production is regulated by relA and rsh genes in Streptomyces clavuligerus ATCC27064.

Journal of biotechnology 20041019

Pharmacological and functional biochemical properties of D-Ala2-D-Nle5-enkephalin-Arg-Phe.

Regulatory peptides 20041015

MicroRNA genes are transcribed by RNA polymerase II.

The EMBO journal 20041013

Use of chelating ligands to tune the reactive site of half-sandwich ruthenium(II)-arene anticancer complexes.

Chemistry (Weinheim an der Bergstrasse, Germany) 20041011

Acid-base properties of xanthosine 5'-monophosphate (XMP) and of some related nucleobase derivatives in aqueous solution: micro acidity constant evaluations of the (N1)H versus the (N3)H deprotonation ambiguity.

Chemistry (Weinheim an der Bergstrasse, Germany) 20041011

Identification of CC chemokine receptor 7 residues important for receptor activation.

The Journal of biological chemistry 20041008

Guanosine selectively inhibits locomotor stimulation induced by the NMDA antagonist dizocilpine.

Behavioural brain research 20041005

8-Bromo-cAMP decreases the Ca2+ sensitivity of airway smooth muscle contraction through a mechanism distinct from inhibition of Rho-kinase.

American journal of physiology. Lung cellular and molecular physiology 20041001

Downregulation of cGMP-dependent protein kinase-1 activity in the corpus cavernosum smooth muscle of diabetic rabbits.

American journal of physiology. Regulatory, integrative and comparative physiology 20041001

Erythropoietin and hypoxia stimulate erythropoietin receptor and nitric oxide production by endothelial cells.

Blood 20041001

Characterization of three novel members of the Arabidopsis thaliana equilibrative nucleoside transporter (ENT) family.

The Biochemical journal 20041001

Cocaine alters GABA(B)-mediated G-protein activation in the ventral tegmental area of female rats: modulation by estrogen.

Synapse (New York, N.Y.) 20041001

Mycophenolates in transplantation.

Clinical transplantation 20041001

Spectroscopic characterization of fluorescein- and tetramethylrhodamine-labeled oligonucleotides and their complexes with a DNA template.

Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20041001

Neuronal RNA oxidation is a prominent feature of familial Alzheimer's disease.

Neurobiology of disease 20041001

Benzimidazole derivatives. Part 5: design and synthesis of new benzimidazole-arylpiperazine derivatives acting as mixed 5-HT1A/5-HT3 ligands.

Bioorganic & medicinal chemistry 20041001

Evidence for biological effects of exogenous LPA on rat primary afferent and spinal cord neurons.

Brain research 20041001

Stimulation of cyclic GMP efflux in human melanocytes by hypergravity generated by centrifugal acceleration.

Pigment cell research 20041001

Overexpression and functional characterisation of the human melanocortin 4 receptor in Sf9 cells.

Protein expression and purification 20041001

The influence of DNA stiffness upon nucleosome formation.

Journal of structural biology 20041001

Synergistic effects of ANP and sildenafil on cGMP levels and amelioration of acute hypoxic pulmonary hypertension.

Experimental biology and medicine (Maywood, N.J.) 20041001

Nitric oxide-sensitive soluble guanylyl cyclase activity is preserved in internal mammary artery of type 2 diabetic patients.

Diabetes 20041001

Identification and characterization of a novel gene of grouper iridovirus encoding a purine nucleoside phosphorylase.

The Journal of general virology 20041001

Mycophenolic acid inhibits avian reovirus replication.

Antiviral research 20041001

Insulin activates vascular endothelial growth factor in vascular smooth muscle cells: influence of nitric oxide and of insulin resistance.

European journal of clinical investigation 20041001

Determination of glycated nucleobases in human urine by a new monoclonal antibody specific for N2-carboxyethyl-2'-deoxyguanosine.

Chemical research in toxicology 20041001

Dynamin- and clathrin-dependent endocytic pathway in unicellular eukaryote Paramecium.

Biochemistry and cell biology = Biochimie et biologie cellulaire 20041001

Purine nucleoside phosphorylase activity in rat cerebrospinal fluid.

Neurochemical research 20041001

5-(1-Substituted) alkyl pyrimidine nucleosides as antiviral (herpes) agents.

Current medicinal chemistry 20041001

Synthesis and polymerase incorporation of 5'-amino-2',5'-dideoxy-5'-N-triphosphate nucleotides.

Current protocols in nucleic acid chemistry 20041001

Structural basis for packaging the dimeric genome of Moloney murine leukaemia virus.

Nature 20040930

Biochemical brain markers and purinergic parameters in rat CSF after seizure induced by pentylenetetrazol.

Brain research bulletin 20040930

Heterooligomeric phosphoribosyl diphosphate synthase of Saccharomyces cerevisiae: combinatorial expression of the five PRS genes in Escherichia coli.

The Journal of biological chemistry 20040924

Enhancing Hoogsteen interactions: a pyrrole-containing purine nucleoside that competes with guanosine self-assembly.

Journal of the American Chemical Society 20040922

Synthesis, physicochemical and biochemical studies of 1',2'-oxetane constrained adenosine and guanosine modified oligonucleotides, and their comparison with those of the corresponding cytidine and thymidine analogues.

Journal of the American Chemical Society 20040922

In vitro characterization of AR-A000002, a novel 5-hydroxytryptamine(1B) autoreceptor antagonist.

European journal of pharmacology 20040919

Allosteric modulation and constitutive activity of fusion proteins between the adenosine A1 receptor and different 351Cys-mutated Gi alpha-subunits.

European journal of pharmacology 20040919

Characterization of the complex morphinan derivative BU72 as a high efficacy, long-lasting mu-opioid receptor agonist.

European journal of pharmacology 20040919

Perturbing the linker regions of the alpha-subunit of transducin: a new class of constitutively active GTP-binding proteins.

The Journal of biological chemistry 20040917

Mitochondrial fusion intermediates revealed in vitro.

Science (New York, N.Y.) 20040917

Structure of Mycobacterium tuberculosis FtsZ reveals unexpected, G protein-like conformational switches.

Journal of molecular biology 20040917

A transition state analogue for an RNA-editing reaction.

Journal of the American Chemical Society 20040915

G-quartet oligonucleotides: a new class of signal transducer and activator of transcription 3 inhibitors that suppresses growth of prostate and breast tumors through induction of apoptosis.

Cancer research 20040915

Adenosine A1 receptor-dependent G-protein activity in the rat brain during prolonged wakefulness.

Neuroreport 20040915

Stimulation of DNA glycosylase activity of OGG1 by NEIL1: functional collaboration between two human DNA glycosylases.

Biochemistry 20040914

Regulation of the coupling to different G proteins of rat corticotropin-releasing factor receptor type 1 in human embryonic kidney 293 cells.

The Journal of biological chemistry 20040910

Error-prone replication of oxidatively damaged DNA by a high-fidelity DNA polymerase.

Nature 20040909

Hydrolytic reactions of guanosyl-(3',3')-uridine and guanosyl-(3',3')-(2',5'-di-O-methyluridine).

Journal of the American Chemical Society 20040908

Dysregulation of apoptosis by benzene metabolites and their relationships with carcinogenesis.

Biochimica et biophysica acta 20040906

Ectopically expressed gamma-aminobutyric acid receptor B is functionally down-regulated in isolated lipid raft-enriched membranes.

Biochemical and biophysical research communications 20040903

Chronic antidepressant treatment causes a selective reduction of mu-opioid receptor binding and functional coupling to G Proteins in the amygdala of fawn-hooded rats.

The Journal of pharmacology and experimental therapeutics 20040901

Solution structure of an RNA stem-loop derived from the 3' conserved region of eel LINE UnaL2.

RNA (New York, N.Y.) 20040901

Pharmacological and behavioral properties of A-349821, a selective and potent human histamine H3 receptor antagonist.

Biochemical pharmacology 20040901

Electrochemical study of quercetin-DNA interactions: part I. Analysis in incubated solutions.

Bioelectrochemistry (Amsterdam, Netherlands) 20040901

Electrochemical study of quercetin-DNA interactions: part II. In situ sensing with DNA biosensors.

Bioelectrochemistry (Amsterdam, Netherlands) 20040901

Targeted disruption of PSD-93 gene reduces platelet-activating factor-induced neurotoxicity in cultured cortical neurons.

Experimental neurology 20040901

Structural basis for the dual coding potential of 8-oxoguanosine by a high-fidelity DNA polymerase.

The EMBO journal 20040901

Structure-activity studies on high affinity NOP-active hexapeptides.

The journal of peptide research : official journal of the American Peptide Society 20040901

Single-base oligodeoxyguanosine-binding proteins on nonspecific cytotoxic cells: identification of a new class of pattern-recognition receptors.

Scandinavian journal of immunology 20040901

Mesenchymal stem cells inhibit the expression of CD25 (interleukin-2 receptor) and CD38 on phytohaemagglutinin-activated lymphocytes.

Scandinavian journal of immunology 20040901

Functional role of a C-terminal Gbetagamma-binding domain of Ca(v)2.2 channels.

Molecular pharmacology 20040901

C-type natriuretic peptide as a podocyte hormone and modulation of its cGMP production by glucose and mechanical stress.

Kidney international 20040901

Protein kinase B, P34cdc2 kinase, and p21 ras GTP-binding in kidneys of aging rats.

Experimental biology and medicine (Maywood, N.J.) 20040901

Modulation of extracellular signal-regulated kinase (ERK) activity by acute and chronic opioid treatment in neuronal and glial cell lines.

Journal of neurochemistry 20040901

Cytokine-induced nitric oxide inhibits mitochondrial energy production and induces myocardial dysfunction in endotoxin-treated rat hearts.

Journal of molecular and cellular cardiology 20040901

RGS 2 expression is regulated by TSH and inhibits TSH receptor signaling.

European journal of endocrinology 20040901

The binding selectivity of ADAR2's dsRBMs contributes to RNA-editing selectivity.

Chemistry & biology 20040901

Effect of lead ions on rat erythrocyte purine content.

Biological trace element research 20040901

[Determination of four nucleosides in Banlangen injections using capillary zone electrophoresis].

Se pu = Chinese journal of chromatography 20040901

Efficiency of repair of an abasic site within DNA clustered damage sites by mammalian cell nuclear extracts.

Biochemistry 20040831

N2-methylation of guanosine at position 10 in tRNA is catalyzed by a THUMP domain-containing, S-adenosylmethionine-dependent methyltransferase, conserved in Archaea and Eukaryota.

The Journal of biological chemistry 20040827

Alpha1B-adrenoceptor signaling and cell motility: GTPase function of Gh/transglutaminase 2 inhibits cell migration through interaction with cytoplasmic tail of integrin alpha subunits.

The Journal of biological chemistry 20040827

A new approach to natural products discovery exemplified by the identification of sulfated nucleosides in spider venom.

Journal of the American Chemical Society 20040825

Cell-specific manipulation of second messengers; a toolbox for integrative physiology in Drosophila.

Current biology : CB 20040824

A structural basis for the inhibition of the NS5 dengue virus mRNA 2'-O-methyltransferase domain by ribavirin 5'-triphosphate.

The Journal of biological chemistry 20040820

Elevated expression level of 60-kDa subunit of tRNA-guanine transglycosylase in colon cancer.

Cancer letters 20040820

Quinolinic acid promotes seizures and decreases glutamate uptake in young rats: reversal by orally administered guanosine.

Brain research 20040820

5-Cyanoimino-4-oxomethylene-4,5-dihydroimidazole and 5-cyanoamino-4-imidazolecarboxylic acid intermediates in nitrosative guanosine deamination: evidence from 18O-labeling experiments.

Journal of the American Chemical Society 20040818

Altered permeability and modulatory character of connexin channels during mammary gland development.

Experimental cell research 20040815

Characterization of MOCS1A, an oxygen-sensitive iron-sulfur protein involved in human molybdenum cofactor biosynthesis.

The Journal of biological chemistry 20040813

Mepyramine, a histamine H1 receptor inverse agonist, binds preferentially to a G protein-coupled form of the receptor and sequesters G protein.

The Journal of biological chemistry 20040813

Tricyclic alkylamides as melatonin receptor ligands with antagonist or inverse agonist activity.

Journal of medicinal chemistry 20040812

Spermine participates in oxidative damage of guanosine and 8-oxoguanosine leading to deoxyribosylurea formation.

Journal of the American Chemical Society 20040811

A novel series of 2-pyridyl-containing compounds as lysophosphatidic acid receptor antagonists: development of a nonhydrolyzable LPA3 receptor-selective antagonist.

Bioorganic & medicinal chemistry letters 20040802

Characterisation of GEA 3175 on human platelets; comparison with S-nitroso-N-acetyl-D,L-penicillamine.

European journal of pharmacology 20040802

DiPOA ([8-(3,3-diphenyl-propyl)-4-oxo-1-phenyl-1,3,8-triazaspiro[4.5]dec-3-yl]-acetic acid), a novel, systemically available, and peripherally restricted mu opioid agonist with antihyperalgesic activity: I. In vitro pharmacological characterization and pharmacokinetic properties.

The Journal of pharmacology and experimental therapeutics 20040801

High-dose intravenous vitamin C is not associated with an increase of pro-oxidative biomarkers.

European journal of clinical nutrition 20040801

Altered calcium-induced exocytosis in neutrophils from allergic patients.

International archives of allergy and immunology 20040801

Shift in nucleotide conformational equilibrium contributes to increased rate of catalysis of GpAp versus GpA in barnase.

Proteins 20040801

KMUP-1, a xanthine derivative, induces relaxation of guinea-pig isolated trachea: the role of the epithelium, cyclic nucleotides and K+ channels.

British journal of pharmacology 20040801

Drug design and synthesis of epsilon opioid receptor agonist: 17-(cyclopropylmethyl)-4,5alpha-epoxy-3,6beta-dihydroxy-6,14-endoethenomorphinan-7alpha-(N-methyl-N-phenethyl)carboxamide (TAN-821) inducing antinociception mediated by putative epsilon opioid receptor.

Bioorganic & medicinal chemistry 20040801

A highly pathogenic porcine reproductive and respiratory syndrome virus generated from an infectious cDNA clone retains the in vivo virulence and transmissibility properties of the parental virus.

Virology 20040801

Apoptosis in ischemic renal injury: roles of GTP depletion and p53.

Kidney international 20040801

Dynamic nucleation of Golgi apparatus assembly from the endoplasmic reticulum in interphase hela cells.

Traffic (Copenhagen, Denmark) 20040801

High-affinity interactions between human alpha1A-adrenoceptor C-terminal splice variants produce homo- and heterodimers but do not generate the alpha1L-adrenoceptor.

Molecular pharmacology 20040801

Identification of a novel site within G protein alpha subunits important for specificity of receptor-G protein interaction.

Molecular pharmacology 20040801

Sevoflurane promotes endothelium-dependent smooth muscle relaxation in isolated human omental arteries and veins.

Anesthesia and analgesia 20040801

In vivo selection reveals combinatorial controls that define a critical exon in the spinal muscular atrophy genes.

RNA (New York, N.Y.) 20040801

The antibody-capture [(35)S]GTPgammaS scintillation proximity assay: a powerful emerging technique for analysis of GPCR pharmacology.

Trends in pharmacological sciences 20040801

A reversible gel for chiral separations.

Analytical chemistry 20040801

Regulation of dopamine D-receptor activation in vivo by protein phosphatase 2B (calcineurin).

Journal of neurochemistry 20040801

Beyond genetics--the emerging role of epigenetic changes in hematopoietic malignancies.

International journal of hematology 20040801

Enzymatic transesterification of purine nucleoside having a low solubility in organic medium.

Biotechnology letters 20040801

Effect of insulin on spontaneous and progesterone-induced GVBD on Bufo arenarum denuded oocytes.

Zygote (Cambridge, England) 20040801

Staurosporine restores GTPgammaS induced block of rapid endocytosis in chromaffin cells.

FEBS letters 20040730

Transient silylation of the guanosine O6 and amino groups facilitates N-acylation.

Organic letters 20040722

Isolation and characterization of the human tRNA-(N1G37) methyltransferase (TRM5) and comparison to the Escherichia coli TrmD protein.

Biochemistry 20040720

Clinical significance of elongation factor-1 delta mRNA expression in oesophageal carcinoma.

British journal of cancer 20040719

Changes in purine levels and adenosine receptors in kindled seizures in the rat.

Neuroreport 20040719

Increased baclofen-stimulated G protein coupling and deactivation in rat brain cortex during development.

Brain research. Developmental brain research 20040719

Differential effects of gestational buprenorphine, naloxone, and methadone on mesolimbic mu opioid and ORL1 receptor G protein coupling.

Brain research. Developmental brain research 20040719

Identification of the region in Cdc42 that confers the binding specificity to activated Cdc42-associated kinase.

The Journal of biological chemistry 20040716

CCL3, acting via the chemokine receptor CCR5, leads to independent activation of Janus kinase 2 (JAK2) and Gi proteins.

FEBS letters 20040716

Actions downstream of cyclic GMP/protein kinase G can reverse protein kinase C-mediated phosphorylation of CPI-17 and Ca²⁺ sensitization in smooth muscle.

The Journal of biological chemistry 20040709

Characterization of the pharmacology of imidazolidinedione derivatives at cannabinoid CB1 and CB2 receptors.

European journal of pharmacology 20040708

Conformational properties of shape modified nucleosides--fleximers.

Journal of the American Chemical Society 20040707

Reactions of 9-substituted guanines with bromomalondialdehyde in aqueous solution predominantly yield glyoxal-derived adducts.

Organic & biomolecular chemistry 20040707

Effect of nonsteroidal anti-inflammatory drugs on beta-catenin protein levels and catenin-related transcription in human colorectal cancer cells.

British journal of cancer 20040705

Rapid desensitization of G protein-gated inwardly rectifying K(+) currents is determined by G protein cycle.

American journal of physiology. Cell physiology 20040701

Cloning and pharmacological characterization of CXCR1 and CXCR2 from Macaca fascicularis.

The Journal of pharmacology and experimental therapeutics 20040701

Prostaglandin E2 activates outwardly rectifying Cl(-) channels via a cAMP-dependent pathway and reduces cell motility in rat osteoclasts.

American journal of physiology. Cell physiology 20040701

Guanine nucleotides inhibit NMDA and kainate-induced neurotoxicity in cultured rat hippocampal and neocortical neurons.

Neurochemistry international 20040701

Antitussive profile of the NOP agonist Ro-64-6198 in the guinea pig.

Pharmacology 20040701

Solution structure of hypothetical Nudix hydrolase DR0079 from extremely radiation-resistant Deinococcus radiodurans bacterium.

Proteins 20040701

Cannabinoid signaling in rat cerebellar granule cells: G-protein activation, inhibition of glutamate release and endogenous cannabinoids.

Neuropharmacology 20040701

Analysis of the monocyte chemoattractant protein 1 -2518 promoter polymorphism in patients with multiple sclerosis.

Tissue antigens 20040701

'Low' concentrations of sodium fluoride inhibit neurotransmitter release from the guinea-pig superior cervical ganglion.

Neuroscience letters 20040701

Biochemical characterization of the coating mechanism of the endosomal donor compartment of synaptic vesicles.

Neurochemical research 20040701

Adenosine down-regulates the surface expression of dipeptidyl peptidase IV on HT-29 human colorectal carcinoma cells: implications for cancer cell behavior.

The American journal of pathology 20040701

Anesthetics inhibit acetylcholine-promoted guanine nucleotide exchange of heterotrimeric G proteins of airway smooth muscle.

Anesthesiology 20040701

Inhibition of melatonin-induced ascorbic acid and LHRH release by a nitric oxide synthase and cyclic GMP inhibitor.

Experimental biology and medicine (Maywood, N.J.) 20040701

The dg2 (for) gene confers a renal phenotype in Drosophila by modulation of cGMP-specific phosphodiesterase.

The Journal of experimental biology 20040701

Inhibition of neutral sodium absorption by a prostaglandin analogue in patients with cystic fibrosis.

Gastroenterology 20040701

Ontogenetic profile of glutamate uptake in brain structures slices from rats: sensitivity to guanosine.

Mechanisms of ageing and development 20040701

Functional responses to the cannabinoid agonist WIN 55,212-2 in neonatal rats of both genders: influence of weaning.

Pharmacology, biochemistry, and behavior 20040701

Impaired synthesis and action of antiaggregating cyclic nucleotides in platelets from obese subjects: possible role in platelet hyperactivation in obesity.

European journal of clinical investigation 20040701

Use of a native affinity ligand for the detection of G proteins by capillary isoelectric focusing with laser-induced fluorescence detection.

Electrophoresis 20040701

Receptor binding kinetics and cellular responses of six N-formyl peptide agonists in human neutrophils.

Biochemistry 20040629

Cloning and pharmacological characterisation of the guinea pig 5-ht5A receptor.

European journal of pharmacology 20040628

Na+ modulation, inverse agonism, and anorectic potency of 4-phenylpiperidine opioid antagonists.

European journal of pharmacology 20040628

Identification and characterization of AGS4: a protein containing three G-protein regulatory motifs that regulate the activation state of Gialpha.

The Journal of biological chemistry 20040625

The Escherichia coli 3-methyladenine DNA glycosylase AlkA has a remarkably versatile active site.

The Journal of biological chemistry 20040625

Crystal structure of transglutaminase 3 in complex with GMP: structural basis for nucleotide specificity.

The Journal of biological chemistry 20040618

Morphine-induced changes in delta opioid receptor trafficking are linked to somatosensory processing in the rat spinal cord.

The Journal of neuroscience : the official journal of the Society for Neuroscience 20040616

Vesicle transport in oligodendrocytes: probable role of Rab40c protein.

Journal of neuroscience research 20040615

Distinct origins of tRNA(m1G37) methyltransferase.

Journal of molecular biology 20040611

Initial structure-activity relationships of lysophosphatidic acid receptor antagonists: discovery of a high-affinity LPA1/LPA3 receptor antagonist.

Bioorganic & medicinal chemistry letters 20040607

Inhibition by bis(7)-tacrine of 5-HT-activated current in rat TG neurons.

Neuroreport 20040607

Long-chain adducts of trans-4-hydroxy-2-nonenal to DNA bases cause recombination, base substitutions and frameshift mutations in M13 phage.

Mutation research 20040604

Agonist-induced serotonin 2A receptor desensitization in the rat frontal cortex and hypothalamus.

The Journal of pharmacology and experimental therapeutics 20040601

S32504, a novel naphtoxazine agonist at dopamine D3/D2 receptors: I. Cellular, electrophysiological, and neurochemical profile in comparison with ropinirole.

The Journal of pharmacology and experimental therapeutics 20040601

A high-throughput and sensitive methodology for the quantification of urinary 8-hydroxy-2'-deoxyguanosine: measurement with gas chromatography-mass spectrometry after single solid-phase extraction.

The Biochemical journal 20040601

Opioid peptide receptor studies. 17. Attenuation of chronic morphine effects after antisense oligodeoxynucleotide knock-down of RGS9 protein in cells expressing the cloned Mu opioid receptor.

Synapse (New York, N.Y.) 20040601

Nucleosides and ODN electrochemical detection onto boron doped diamond electrodes.

Bioelectrochemistry (Amsterdam, Netherlands) 20040601

G protein-mediated dysfunction of excitation-contraction coupling in ileal inflammation.

American journal of physiology. Gastrointestinal and liver physiology 20040601

Enhanced G-protein activation by a mixture of Abeta(25-35), Abeta(1-40/42) and zinc.

Journal of neurochemistry 20040601

Choline availability modulates human neuroblastoma cell proliferation and alters the methylation of the promoter region of the cyclin-dependent kinase inhibitor 3 gene.

Journal of neurochemistry 20040601

Plasma purine nucleoside phosphorylase in cancer patients.

Clinica chimica acta; international journal of clinical chemistry 20040601

Expression of natriuretic peptides, nitric oxide synthase, and guanylate cyclase activity in frog mesonephros during the annual cycle.

General and comparative endocrinology 20040601

Mechanisms involved in carbachol-induced Ca(2+) sensitization of contractile elements in rat proximal and distal colon.

British journal of pharmacology 20040601

Unique roles of the rrn P2 rRNA promoters in Escherichia coli.

Molecular microbiology 20040601

The quormone degradation system of Agrobacterium tumefaciens is regulated by starvation signal and stress alarmone (p)ppGpp.

Molecular microbiology 20040601

Molecular cloning of a putative membrane form guanylyl cyclase from the crayfish Procambarus clarkii.

Journal of experimental zoology. Part A, Comparative experimental biology 20040601

Effects of RNA polymerase modifications on transcription-induced negative supercoiling and associated R-loop formation.

Molecular microbiology 20040601

The bacterial signal molecule, ppGpp, regulates Salmonella virulence gene expression.

Molecular microbiology 20040601

Renal secretion of the antiviral nucleoside analog AM188 is inhibited by probenecid, p-aminohippuric acid, and cimetidine in the isolated perfused rat kidney.

Pharmaceutical research 20040601

Phospholipase C involvement in activation of the muscarinic receptor-operated cationic current in Guinea pig ileal smooth muscle cells.

Journal of pharmacological sciences 20040601

Cooperative effects in the photophysical properties of self-associated triguanosine diphosphates.

Photochemistry and photobiology 20040601

Structural plasticity of the adult brain: how animal models help us understand brain changes in depression and systemic disorders related to depression.

Dialogues in clinical neuroscience 20040601

Identification of a G protein-coupled receptor specifically responsive to beta-alanine.

The Journal of biological chemistry 20040528

Artificial genetic systems: exploiting the 'aromaticity' formalism to improve the tautomeric ratio for isoguanosine derivatives.

The Journal of organic chemistry 20040528

Cholesterol modulates ligand binding and G-protein coupling to serotonin(1A) receptors from bovine hippocampus.

Biochimica et biophysica acta 20040527

Cadmium inhibits GABA-activated ion currents by increasing intracellular calcium level in snail neurons.

Brain research 20040522

The M3 receptor-mediated K(+) current (IKM3), a G(q) protein-coupled K(+) channel.

The Journal of biological chemistry 20040521

SAR development of a selective 5-HT1D antagonist/serotonin reuptake inhibitor lead using rapid parallel synthesis.

Bioorganic & medicinal chemistry letters 20040517

Single base oligodeoxyguanosine upregulates Fas ligand release by nonspecific cytotoxic cells.

Developmental and comparative immunology 20040517

Mutation of leucine-92 selectively reduces the apparent affinity of inosine, guanosine, NBMPR [S6-(4-nitrobenzyl)-mercaptopurine riboside] and dilazep for the human equilibrative nucleoside transporter, hENT1.

The Biochemical journal 20040515

Binding differences of human and amphibian corticotropin-releasing factor type 1 (CRF(1)) receptors: identification of amino acids mediating high-affinity astressin binding and functional antagonism.

Regulatory peptides 20040515

Cinnamic amides of (S)-2-(aminomethyl)pyrrolidines are potent H3 antagonists.

Bioorganic & medicinal chemistry 20040515

Influence of electric charge variation at residues 209 and 159 on the interaction of eIF4E with the mRNA 5' terminus.

Biochemistry 20040511

Differential inhibition of adenylyl cyclase isoforms and soluble guanylyl cyclase by purine and pyrimidine nucleotides.

The Journal of biological chemistry 20040507

4-(omega-(alkyloxy)alkyl)-1H-imidazole derivatives as histamine H(3) receptor antagonists/agonists.

Journal of medicinal chemistry 20040506

SRA880, in vitro characterization of the first non-peptide somatostatin sst(1) receptor antagonist.

Neuroscience letters 20040506

N,N-dialkyl-4-[(8-azabicyclo[3.2.1]-oct-3-ylidene)phenylmethyl]benzamides, potent, selective delta opioid agonists.

Bioorganic & medicinal chemistry letters 20040503

The cofactor of the iron-sulfur cluster free hydrogenase hmd: structure of the light-inactivation product.

Angewandte Chemie (International ed. in English) 20040503

Guanine derivatives modulate L-glutamate uptake into rat brain synaptic vesicles.

Neurochemistry international 20040501

P2Y purinergic receptor regulation of CFTR chloride channels in mouse cardiac myocytes.

The Journal of physiology 20040501

Renal interstitial guanosine cyclic 3', 5'-monophosphate mediates pressure-natriuresis via protein kinase G.

Hypertension (Dallas, Tex. : 1979) 20040501

delta-Opioid receptor antagonists inhibit GIRK channel currents in acutely dissociated brainstem neurons of rat.

Brain research 20040501

Investigation of the mechanism of agonist and inverse agonist action at D2 dopamine receptors.

Biochemical pharmacology 20040501

The antiapoptotic effect of guanosine is mediated by the activation of the PI 3-kinase/AKT/PKB pathway in cultured rat astrocytes.

Glia 20040501

Regulation of uterine function: a biochemical conundrum in the regulation of smooth muscle relaxation.

Molecular pharmacology 20040501

Two relA/spoT homologous genes are involved in the morphological and physiological differentiation of Streptomyces clavuligerus.

Microbiology (Reading, England) 20040501

Arg(184)His mutant GTP cyclohydrolase I, causing recessive hyperphenylalaninemia, is responsible for dopa-responsive dystonia with parkinsonism: a case report.

Movement disorders : official journal of the Movement Disorder Society 20040501

Competition between lithium and magnesium ions for the G-protein transducin in the guanosine 5'-diphosphate bound conformation.

Journal of inorganic biochemistry 20040501

GABA(B) receptors in 5-HT transporter- and 5-HT1A receptor-knock-out mice: further evidence of a transduction pathway shared with 5-HT1A receptors.

Journal of neurochemistry 20040501

Nucleotides in sow colostrum and milk at different stages of lactation.

Journal of animal science 20040501

Antibodies to guanosine triphosphate misidentified as anti-double-stranded DNA antibodies in a patient with antinuclear antibody-negative lupus, due to buckling of insolubilized assay DNA.

Arthritis and rheumatism 20040501

The receptor-Galpha fusion protein as a tool for ligand screening: a model study using a nociceptin receptor-Galphai2 fusion protein.

Journal of biochemistry 20040501

Inhibitors of measles virus.

Antiviral chemistry & chemotherapy 20040501

A conformationally constrained nucleotide analogue controls the folding topology of a DNA g-quadruplex.

Journal of the American Chemical Society 20040428

Galphai1 and Galphai3 differentially interact with, and regulate, the G protein-activated K+ channel.

The Journal of biological chemistry 20040423

Cholinergic modulation of L-type calcium current in isolated sensory hair cells of the statocyst of octopus, Eledone cirrhosa.

Neuroscience letters 20040422

CG base pair recognition by substituted phenylimidazole nucleosides.

Organic & biomolecular chemistry 20040421

Carbon monoxide: to boldly go where NO has gone before.

Science's STKE : signal transduction knowledge environment 20040420

Anticonvulsant effect of GMP depends on its conversion to guanosine.

Brain research 20040416

Cdc42 and mDia3 regulate microtubule attachment to kinetochores.

Nature 20040415

Nucleic acid analysis using an expanded genetic alphabet to quench fluorescence.

Journal of the American Chemical Society 20040414

Replication-dependent 65R-->K reversion in human immunodeficiency virus type 1 reverse transcriptase double mutant K65R + L74V.

Virology 20040410

Ca2+ and phosphatidylinositol 4,5-bisphosphate stabilize a Gbeta gamma-sensitive state of Ca V2 Ca 2+ channels.

The Journal of biological chemistry 20040409

Crystal structure of purine nucleoside phosphorylase from Thermus thermophilus.

Journal of molecular biology 20040409

Apoptotic signaling in response to a single type of DNA lesion, O(6)-methylguanine.

Molecular cell 20040409

Effects of chronic ethanol administration and ethanol withdrawal on cyclic guanosine 3',5'-monophosphate (cGMP) levels in the rat brain.

Drug and alcohol dependence 20040409

Guanosine protects SH-SY5Y cells against beta-amyloid-induced apoptosis.

Neuroreport 20040409

Alkylation of guanosine and 2'-deoxyguanosine by o-quinone alpha-(p-anisyl)methide in aqueous solution.

Organic & biomolecular chemistry 20040407

DNA nucleosides and their radical anions: molecular structures and electron affinities.

Journal of the American Chemical Society 20040407

Real-time analysis of ternary complex on particles: direct evidence for partial agonism at the agonist-receptor-G protein complex assembly step of signal transduction.

The Journal of biological chemistry 20040402

Sphingosine 1-phosphate (S1P) receptor subtypes S1P1 and S1P3, respectively, regulate lymphocyte recirculation and heart rate.

The Journal of biological chemistry 20040402

Furin is a chemokine-modifying enzyme: in vitro and in vivo processing of CXCL10 generates a C-terminally truncated chemokine retaining full activity.

The Journal of biological chemistry 20040402

Functional coupling of the nociceptin/orphanin FQ receptor in dog brain membranes.

Brain research 20040402

Conformational antagonism between opposing active sites in a bifunctional RelA/SpoT homolog modulates (p)ppGpp metabolism during the stringent response [corrected].

Cell 20040402

Among circulating hematopoietic cells, B-CLL uniquely expresses functional EPAC1, but EPAC1-mediated Rap1 activation does not account for PDE4 inhibitor-induced apoptosis.

Blood 20040401

Description of glucose transport in isolated bovine mammary epithelial cells by a three-compartment model.

American journal of physiology. Cell physiology 20040401

Delta-opioid agonists: differential efficacy and potency of SNC80, its 3-OH (SNC86) and 3-desoxy (SNC162) derivatives in Sprague-Dawley rats.

The Journal of pharmacology and experimental therapeutics 20040401

Redox modulation of Gi protein expression and adenylyl cyclase signaling: role of nitric oxide.

Antioxidants & redox signaling 20040401

Practical and general synthesis of 5'-adenylated RNA (5'-AppRNA).

RNA (New York, N.Y.) 20040401

The hyperthermophilic origin of life revisited.

Biochemical Society transactions 20040401

Deep knot structure for construction of active site and cofactor binding site of tRNA modification enzyme.

Structure (London, England : 1993) 20040401

Cyclic di-guanosine-monophosphate comes of age: a novel secondary messenger involved in modulating cell surface structures in bacteria?

Current opinion in microbiology 20040401

Role of ATP-sensitive K+ channels in relaxation of penile resistance arteries.

Urology 20040401

Time-dependent inhibition of G protein-coupled receptor signaling by local anesthetics.

Anesthesiology 20040401

Characterization and quantitative analysis of DNA adducts formed from lower chlorinated PCB-derived quinones.

Chemical research in toxicology 20040401

Melatonin binding sites in the brain of European sea bass (Dicentrarchus labrax).

Zoological science 20040401

Involvement of G proteins in the mycelial photoresponses of Phycomyces.

Photochemistry and photobiology 20040401

Detection of cannabinoid CB1, adenosine A1, muscarinic acetylcholine, and GABA(B) receptor-dependent G protein activity in transducin-deactivated membranes and autoradiography sections of rat retina.

Cellular and molecular neurobiology 20040401

[Study on the chemical constituents of Selaginella tamariscina (Beauv.) Spring].

Yao xue xue bao = Acta pharmaceutica Sinica 20040401

Ligand binding characteristics of the human serotonin1A receptor heterologously expressed in CHO cells.

Bioscience reports 20040401

Constitutive activity of the serotonin2C receptor inhibits in vivo dopamine release in the rat striatum and nucleus accumbens.

The Journal of neuroscience : the official journal of the Society for Neuroscience 20040331

Application of an immunoperoxidase staining method for detection of 7,8-dihydro-8-oxodeoxyguanosine as a biomarker of chemical-induced oxidative stress in marine organisms.

Aquatic toxicology (Amsterdam, Netherlands) 20040330

Clostridium perfringens alpha-toxin activates the sphingomyelin metabolism system in sheep erythrocytes.

The Journal of biological chemistry 20040326

Structure-activity study of the ORL1 antagonist Ac-Arg-D-Cha-Qaa-D-Arg-D-p-ClPhe-NH2.

Journal of medicinal chemistry 20040325

Neurochemical and behavioral alterations in glucocorticoid receptor-impaired transgenic mice after chronic mild stress.

The Journal of neuroscience : the official journal of the Society for Neuroscience 20040317

Ceramide inhibition of phospholipase D and its relationship to RhoA and ARF1 translocation in GTP gamma S-stimulated polymorphonuclear leukocytes.

Blood 20040315

Guanine nucleotide dissociation inhibitor activity of the triple GoLoco motif protein G18: alanine-to-aspartate mutation restores function to an inactive second GoLoco motif.

The Biochemical journal 20040315

Oxidative stress in severe pulmonary hypertension.

American journal of respiratory and critical care medicine 20040315

Reactive oxygen species derived from the mitochondrial respiratory chain are not responsible for the basal levels of oxidative base modifications observed in nuclear DNA of Mammalian cells.

Free radical biology & medicine 20040315

Adenosine-dependent assembly of aptazyme-functionalized gold nanoparticles and its application as a colorimetric biosensor.

Analytical chemistry 20040315

Transcription factors NF-YA regulate the induction of human OGG1 following DNA-alkylating agent methylmethane sulfonate (MMS) treatment.

The Journal of biological chemistry 20040312

Munc13-4 is a GTP-Rab27-binding protein regulating dense core granule secretion in platelets.

The Journal of biological chemistry 20040312

Action of the muscarinic toxin MT7 on agonist-bound muscarinic M1 receptors.

European journal of pharmacology 20040308

Antiobesity effects of A-331440, a novel non-imidazole histamine H3 receptor antagonist.

European journal of pharmacology 20040308

Species-specific recognition of single-stranded RNA via toll-like receptor 7 and 8.

Science (New York, N.Y.) 20040305

Site-specific modification of Epstein-Barr virus-encoded RNA 1 with N2-benzylguanosine limits the binding sites occupied by PKR.

Chembiochem : a European journal of chemical biology 20040305

Guanosine distribution and oxidation resistance in eight eukaryotic genomes.

Journal of the American Chemical Society 20040303

Reduced renal dopamine D1 receptor function in streptozotocin-induced diabetic rats.

American journal of physiology. Renal physiology 20040301

Epinephrine-induced hyperpolarization of islet cells without KATP channels.

American journal of physiology. Endocrinology and metabolism 20040301

Characterization of N-(1-Acetyl-2,3-dihydro-1H-indol-6-yl)-3-(3-cyano-phenyl)-N-[1-(2-cyclopentyl-ethyl)-piperidin-4yl]acrylamide (JNJ-5207787), a small molecule antagonist of the neuropeptide Y Y2 receptor.

The Journal of pharmacology and experimental therapeutics 20040301

Actions of noradrenaline on substantia gelatinosa neurones in the rat spinal cord revealed by in vivo patch recording.

The Journal of physiology 20040301

Guanine nucleotide depletion triggers cell cycle arrest and apoptosis in human neuroblastoma cell lines.

International journal of cancer 20040301

An autoradiographic study of the influence of pindolol upon [35S]GTPgammaS binding in rat, guinea pig and human brain.

The international journal of neuropsychopharmacology 20040301

Single cGMP-activated Ca(+)-dependent Cl(-) channels in rat mesenteric artery smooth muscle cells.

The Journal of physiology 20040301

Functional group recognition at the aminoacylation and editing sites of E. coli valyl-tRNA synthetase.

RNA (New York, N.Y.) 20040301

The effects of hexanol on Galpha(i) subunits of heterotrimeric G proteins.

Anesthesia and analgesia 20040301

Inhibition of thrombosis by a novel platelet selective S-nitrosothiol compound without hemodynamic side effects.

Cardiovascular research 20040301

Attenuation of renal injury in db/db mice overexpressing superoxide dismutase: evidence for reduced superoxide-nitric oxide interaction.

Diabetes 20040301

Carbon monoxide in biology and medicine.

BioEssays : news and reviews in molecular, cellular and developmental biology 20040301

Oral administration of guanosine impairs inhibitory avoidance performance in rats and mice.

Neurobiology of learning and memory 20040301

Nitrosation of glycine ethyl ester and ethyl diazoacetate to give the alkylating agent and mutagen ethyl chloro(hydroximino)acetate.

Chemical research in toxicology 20040301

Evidence for tight coupling of Gi protein-mediated lysophosphatidic acid receptor to stimulated cytokine production in ovarian cancer cell.

American journal of obstetrics and gynecology 20040301

A purified agonist-activated G-protein coupled receptor: truncated octopus Acid Metarhodopsin.

Zoological science 20040301

PACAP inhibits delayed rectifier potassium current via a cAMP/PKA transduction pathway: evidence for the involvement of I k in the anti-apoptotic action of PACAP.

The European journal of neuroscience 20040301

Effect of 2'-deoxyisoguanosine on the growth of human tumor and normal cell lines.

Eksperimental'naia onkologiia 20040301

Purine nucleosides support the neurite outgrowth of primary rat cerebellar granule cells after hypoxia.

European journal of cell biology 20040301

Complexes of copper(II) with adenosine or guanosine nucleosides, nucleotides 5'-monophosphate, 2'-deoxynucleosides or 2'-deoxynucleotides 5'-monophosphate in aqueous solution.

Annali di chimica 20040301

Melanopsin--shedding light on the elusive circadian photopigment.

Chronobiology international 20040301

Relationship between growth rate and ATP concentration in Escherichia coli: a bioassay for available cellular ATP.

The Journal of biological chemistry 20040227

Activation of type I phosphatidylinositol 4-phosphate 5-kinase isoforms by the Rho GTPases, RhoA, Rac1, and Cdc42.

The Journal of biological chemistry 20040227

Monkey corticotropin-releasing factor1 receptor: Complementary DNA cloning and pharmacological characterization.

Life sciences 20040227

Structural basis for the coordinated regulation of transglutaminase 3 by guanine nucleotides and calcium/magnesium.

The Journal of biological chemistry 20040220

Structural insights into the interaction of ROCKI with the switch regions of RhoA.

The Journal of biological chemistry 20040220

A Rho exchange factor mediates fMet-Leu-Phe-induced NF-kappaB activation in human peripheral blood monocytes.

The Journal of biological chemistry 20040220

Alpha-thrombin-mediated phosphatidylinositol 3-kinase activation through release of Gbetagamma dimers from Galphaq and Galphai2.

The Journal of biological chemistry 20040220

Formamidopyrimidines as major products in the low- and high-intensity UV irradiation of guanine derivatives.

Journal of photochemistry and photobiology. B, Biology 20040220

Minimum essential factors required for vesicle mobilization at hippocampal synapses.

The Journal of neuroscience : the official journal of the Society for Neuroscience 20040218

Molecular pharmacology of the ovine melatonin receptor: comparison with recombinant human MT1 and MT2 receptors.

Biochemical pharmacology 20040215

Relationship between the antinociceptive response to desipramine and changes in GABAB receptor function and subunit expression in the dorsal horn of the rat spinal cord.

Biochemical pharmacology 20040215

Modulation of Ca2+ sensitivity by cyclic nucleotides in smooth muscle from protein kinase G-deficient mice.

The Journal of biological chemistry 20040213

Region-dependent G-protein activation by kappa-opioid receptor agonists in the mouse brain.

Neuroscience letters 20040212

Effect of amine ligand bulk on the interaction of methionine with platinum(II) diamine complexes.

Inorganic chemistry 20040209

Design for a binary synapse.

Neuron 20040205

Selective transmission of single photon responses by saturation at the rod-to-rod bipolar synapse.

Neuron 20040205

Recovery of sensorimotor gating without G protein adaptation after repeated D2-like dopamine receptor agonist treatment in rats.

The Journal of pharmacology and experimental therapeutics 20040201

Characterization of mu opioid receptor binding and G protein coupling in rat hypothalamus, spinal cord, and primary afferent neurons during inflammatory pain.

The Journal of pharmacology and experimental therapeutics 20040201

Basal signaling activity of mu opioid receptor in mouse brain: role in narcotic dependence.

The Journal of pharmacology and experimental therapeutics 20040201

Receptor-controlled phosphorylation of alpha 1 soluble guanylyl cyclase enhances nitric oxide-dependent cyclic guanosine 5'-monophosphate production in pituitary cells.

Molecular endocrinology (Baltimore, Md.) 20040201

Specific mutations in the HEXA gene among Iraqi Jewish Tay-Sachs disease carriers: dating of founder ancestor.

Neurogenetics 20040201

Production and role of extracellular guanosine cyclic 3', 5' monophosphate in sodium uptake in human proximal tubule cells.

Hypertension (Dallas, Tex. : 1979) 20040201

Characterization of melatonin binding sites in the brain and retina of the frog Rana perezi.

General and comparative endocrinology 20040201

Gamma-hydroxybutyric acid, unlike gamma-aminobutyric acid, does not stimulate Gi/Go proteins in rat brain membranes.

Basic & clinical pharmacology & toxicology 20040201

Enhanced morphine withdrawal and micro -opioid receptor G-protein coupling in A2A adenosine receptor knockout mice.

Journal of neurochemistry 20040201

Down-regulation of rat brain adenosine A1 receptors at the end of pregnancy.

Journal of neurochemistry 20040201

Sphingosine-1-phosphate induces proliferation and morphological changes of neural progenitor cells.

Journal of neurochemistry 20040201

Nitrergic-purinergic interactions in rat distal colon motility.

Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society 20040201

Decreased cerebrospinal fluid cGMP levels in patients with amyotrophic lateral sclerosis.

Journal of neural transmission (Vienna, Austria : 1996) 20040201

NO-cGMP signaling molecules in the rat epithelial rests of Malassez.

European journal of oral sciences 20040201

Upregulation of CB1 receptors and agonist-stimulated [35S]GTPgammaS binding in the prefrontal cortex of depressed suicide victims.

Molecular psychiatry 20040201

Effect of the manganese ion on human alpha3/4 fucosyltransferase III activity.

Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine 20040201

Pituitary adenylate cyclase activating polypeptide-mediated intracrine signaling in the testicular germ cells.

Endocrine 20040201

Pharmacology of polymorphic variants of the human 5-HT1A receptor.

Biochemical pharmacology 20040201

Diphenylamine-2-carboxylic acid potentiates the cyclic nucleotides-mediated relaxation of porcine coronary artery: possible involvement of the inhibitory effect on the efflux of cyclic nucleotides.

Vascular pharmacology 20040201

The 5-hydroxytryptamine(1A) receptor is stably palmitoylated, and acylation is critical for communication of receptor with Gi protein.

The Journal of biological chemistry 20040130

Dissociated histaminergic neuron cultures from the tuberomammillary nucleus of rats: culture methods and ghrelin effects.

Journal of neuroscience methods 20040130

G-quartets 40 years later: from 5'-GMP to molecular biology and supramolecular chemistry.

Angewandte Chemie (International ed. in English) 20040130

Inhibition of N-type voltage-activated calcium channels in rat dorsal root ganglion neurons by P2Y receptors is a possible mechanism of ADP-induced analgesia.

The Journal of neuroscience : the official journal of the Society for Neuroscience 20040128

Platinum complexes with NH groups on the carrier ligand and with only one guanine or hypoxanthine derivative. Informative models for assessing relative nucleobase and nucleotide hydrogen-bond interactions with amine ligands in solution.

Inorganic chemistry 20040126

Conformers of guanosines and their vibrations in the electronic ground and excited states, as revealed by double-resonance spectroscopy and ab initio calculations.

Chemphyschem : a European journal of chemical physics and physical chemistry 20040123

Substitution reactions of [Pt(terpy)X]2+ with some biologically relevant ligands. Synthesis and crystal structure of [Pt(terpy)(cyst-S)](ClO4)2.0.5H2O and [Pt(terpy)(guo-N7)](ClO4)2.0.5guo.1.5H2O.

Dalton transactions (Cambridge, England : 2003) 20040121

Independent folding and conformational changes of the barnase module in the VL-barnase immunofusion: calorimetric evidence.

FEBS letters 20040116

Effect of phosphodiesterase-5 inhibitor, sildenafil (Viagra), in animal models of airways disease.

American journal of respiratory and critical care medicine 20040115

Estimation of guanine deaminase using guanosine as a 'prosubstrate'.

Analytical biochemistry 20040115

Modulation of A1 adenosine receptor signaling by peroxynitrite.

Biochemical pharmacology 20040115

Sulindac targets nuclear beta-catenin accumulation and Wnt signalling in adenomas of patients with familial adenomatous polyposis and in human colorectal cancer cell lines.

British journal of cancer 20040112

Minihelix-containing RNAs mediate exportin-5-dependent nuclear export of the double-stranded RNA-binding protein ILF3.

The Journal of biological chemistry 20040109

Microchip capillary electrophoresis with a boron-doped diamond electrode for rapid separation and detection of purines.

Journal of chromatography. A 20040102

Characterization of M2 muscarinic receptor activation of different G protein subtypes.

Neurochemistry international 20040101

Assay of G protein-coupled receptor activation of G proteins in native cell membranes using [35S]GTP gamma S binding.

Methods in molecular biology (Clifton, N.J.) 20040101

A combination of oral sildenafil and beraprost ameliorates pulmonary hypertension in rats.

American journal of respiratory and critical care medicine 20040101

Inhibition of G protein-coupled and ATP-sensitive potassium currents by 2-methyl-3-(3,5-diiodo-4-carboxymethoxybenzyl)benzofuran (KB130015), an amiodarone derivative.

The Journal of pharmacology and experimental therapeutics 20040101

In situ evidence of an alternative oxidase and an uncoupling protein in the respiratory chain of Aspergillus fumigatus.

The international journal of biochemistry & cell biology 20040101

Adenine nucleotides inhibit recombinant N-type calcium channels via G protein-coupled mechanisms in HEK 293 cells; involvement of the P2Y13 receptor-type.

British journal of pharmacology 20040101

Carbachol in the pontine reticular formation of C57BL/6J mouse decreases acetylcholine release in prefrontal cortex.

Neuroscience 20040101

Dynamics of the IRE RNA hairpin loop probed by 2-aminopurine fluorescence and stochastic dynamics simulations.

RNA (New York, N.Y.) 20040101

Refinement of the structure of human Rab5a GTPase domain at 1.05 A resolution.

Acta crystallographica. Section D, Biological crystallography 20040101

The small GTP-binding protein RhoA regulates serotonin-induced Na+-current response in the neurons of Aplysia.

Neuroscience research 20040101

Metabolic changes induced by ischemia and cardioplegia: a study employing cardiac microdialysis in pigs.

European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery 20040101

Urinary cyclic GMP excretion and blood pressure levels in a general population.

Atherosclerosis 20040101

Pharmacological characterisation of neuropeptide F (NPF)-induced effects on the motility of Mesocestoides corti (syn. Mesocestoides vogae) larvae.

International journal for parasitology 20040101

Thiochrome enhances acetylcholine affinity at muscarinic M4 receptors: receptor subtype selectivity via cooperativity rather than affinity.

Molecular pharmacology 20040101

Iron supplements: the quick fix with long-term consequences.

Nutrition journal 20040101

Alterations in the natriuretic hormone system related to cardiopulmonary bypass in infants with congestive heart failure.

Pediatric cardiology 20040101

Chronic ethanol consumption reduces delta-and mu-opioid receptor-stimulated G-protein coupling in rat brain.

Alcoholism, clinical and experimental research 20040101

Renal excretion mechanisms of the antiviral nucleoside analogue AM 188 in the rat isolated perfused kidney.

Clinical and experimental pharmacology & physiology 20040101

Excision by the human methylpurine DNA N-glycosylase of cyanuric acid, a stable and mutagenic oxidation product of 8-oxo-7,8-dihydroguanine.

International journal of radiation biology 20040101

A G-quadruplex ligand 3,3'-diethyloxadicarbocyanine iodide induces mitochondrion-mediated apoptosis but not decrease of telomerase activity in nasopharyngeal carcinoma NPC-TW01 cells.

Pharmaceutical research 20040101

Construction and characterization of a kappa opioid receptor devoid of all free cysteines.

Protein engineering, design & selection : PEDS 20040101

Effect of zaprinast on nitric oxide levels in serum and aortic tissue.

Methods and findings in experimental and clinical pharmacology 20040101

Isolated rat kidney perfused with dextran and bovine serum albumin: a stable model for investigating renal drug handling.

Journal of pharmacological and toxicological methods 20040101

Combination of chemical and enzymatic RNA synthesis.

Methods in molecular biology (Clifton, N.J.) 20040101

Dynamic light scattering and 31P NMR study of the self-assembly of deoxyguanosine 5'-monophosphate: the effect of added salt.

The European physical journal. E, Soft matter 20040101

Inhaled nitric oxide: another weapon in our armamentarium in the battle against acute hypoxic respiratory failure in preterm infants.

Critical care (London, England) 20040101

Functional cooperation of Ogg1 and Mutyh in preventing G: C-->T: a transversions in mice.

Fukuoka igaku zasshi = Hukuoka acta medica 20040101

Rearrangement reactions of 1,N2-isopropenoguanine cyclonucleosides.

Nucleosides, nucleotides & nucleic acids 20040101

Functionalization of guanosine and 2'-deoxyguanosine at C6: a modified Appel process and S(N)Ar displacement of imidazole.

Nucleosides, nucleotides & nucleic acids 20040101

Synthesis of nucleoside libraries on solid support. II. 2,6,8-Trisubstituted purine nucleosides using 8-bromoguanosine as precursor.

Nucleosides, nucleotides & nucleic acids 20040101

The excitation cascade of Limulus ventral photoreceptors: guanylate cyclase as the link between InsP3-mediated Ca2+ release and the opening of cGMP-gated channels.

BMC neuroscience 20040101

The stepwise supramolecular organisation of guanosine derivatives.

Chemical record (New York, N.Y.) 20040101

Synthesis and evaluation of ATP-binding site directed potential inhibitors of nucleoside triphosphatases/helicases and polymerases of hepatitis C and other selected Flaviviridae viruses.

Antiviral chemistry & chemotherapy 20040101

Partial A(1) adenosine receptor agonists from a molecular perspective and their potential use as chronic ventricular rate control agents during atrial fibrillation (AF).

Current topics in medicinal chemistry 20040101

Identification of substrates for adenosine deaminases that act on RNA.

Methods in molecular biology (Clifton, N.J.) 20040101

Losartan-induced attenuation of blood pressure in L-NAME hypertensive rats is associated with reversal of the enhanced expression of Gi alpha proteins.

Journal of hypertension 20040101

SIGI: score-based identification of genomic islands.

BMC bioinformatics 20040101

Bench-to-bedside review: understanding genetic predisposition to sepsis.

Critical care (London, England) 20040101

Mechanisms and consequences of methylating agent-induced SCEs and chromosomal aberrations: a long road traveled and still a far way to go.

Cytogenetic and genome research 20040101

Control of pyrimidine biosynthesis in 'Pseudomonas alkanolytica' ATCC 21034.

Journal of basic microbiology 20040101

Oxidative damage to DNA: an immunohistochemical approach for detection of 7,8-dihydro-8-oxodeoxyguanosine in marine organisms.

Marine environmental research 20040101

The synthesis of [([beta-D-ribofuranosyloxy)methyl]nucleosides.

Nucleosides, nucleotides & nucleic acids 20040101

Temperature-dependent interaction of the bovine hippocampal serotonin(1A) receptor with G-proteins.

Molecular membrane biology 20040101

A multi-scale study of industrial fermentation processes and their optimization.

Advances in biochemical engineering/biotechnology 20040101

Impact of 24 h continuous hypothermic perfusion on heart preservation by assessment of oxidative stress.

Clinical transplantation 20040101

Evidence that morphine tolerance may be regulated by endothelin in the neonatal rat.

Biology of the neonate 20040101

Physiology and pathophysiology of vascular signaling controlled by guanosine 3',5'-cyclic monophosphate-dependent protein kinase.

Acta biochimica Polonica 20040101

Determination of rat hepatic polyamines by electron-capture gas chromatography.

Journal of pharmacological and toxicological methods 20040101

Measurement of agonist-stimulated [35S]GTPgammaS binding to assess total G-protein and Galpha-subtype-specific activation by G-protein-coupled receptors.

Methods in molecular biology (Clifton, N.J.) 20040101

Analysis of function of receptor-G-protein and receptor-RGS fusion proteins.

Methods in molecular biology (Clifton, N.J.) 20040101

POSaM: a fast, flexible, open-source, inkjet oligonucleotide synthesizer and microarrayer.

Genome biology 20040101

Short-term cytotoxic effects and long-term instability of RNAi delivered using lentiviral vectors.

BMC molecular biology 20040101

A study comparing the actions of gabapentin and pregabalin on the electrophysiological properties of cultured DRG neurones from neonatal rats.

BMC pharmacology 20040101

Nitric oxide-an endogenous inhibitor of gastric acid secretion in isolated human gastric glands.

BMC gastroenterology 20040101

Cooperation in signal transduction of extracellular guanosine 5' triphosphate and nerve growth factor in neuronal differentiation of PC12 cells.

Neuroscience 20040101

Strickler-Berg analysis of excited singlet state dynamics in DNA and RNA nucleosides.

Faraday discussions 20040101

Regulation of RGS-RhoGEFs by Galpha12 and Galpha13 proteins.

Methods in enzymology 20040101

Purification and functional analysis of Ric-8A: a guanine nucleotide exchange factor for G-protein alpha subunits.

Methods in enzymology 20040101

Purification and in vitro functional analyses of RGS12 and RGS14 GoLoco motif peptides.

Methods in enzymology 20040101

Hypothesis: selective phosphodiesterase-5 inhibition improves outcome in preeclampsia.

Medical hypotheses 20040101

Regulation of tetrahydrobiopterin synthesis and bioavailability in endothelial cells.

Cell biochemistry and biophysics 20040101

Mechanism of ganciclovir uptake by rabbit retina and human retinal pigmented epithelium cell line ARPE-19.

Current eye research 20040101

Selective inhibition of c-Myb DNA-binding by RNA polymers.

BMC biochemistry 20040101

Characterization of G-rich and T-rich oligonucleotides using ion-pair reversed-phase high-performance liquid chromatography/tandem electrospray ionization mass spectrometry.

European journal of mass spectrometry (Chichester, England) 20040101

Genomic structure and cloning of two transcript isoforms of human Sp8.

BMC genomics 20040101

Intracerebroventricular administration of anti-endothelin-1 IgG selectively upregulates endothelin-A and kappa opioid receptors.

Neuroscience 20040101

[Escherichia coli ribosomes as the model to test new photoactivated tRNA analogues, containing 6-thioguanosine].

Molekuliarnaia biologiia 20040101

Expression of phospholipase D isozymes in scar and viable tissue in congestive heart failure due to myocardial infarction.

Journal of cellular and molecular medicine 20040101

In the ventral tegmental area, G-proteins and cAMP mediate the neurosteroid 3alpha,5alpha-THP's actions at dopamine type 1 receptors for lordosis of rats.

Neuroendocrinology 20040101

[Part of the matrix on the 5' side from codon in the E-segment is close to protein S26 on the human 80S ribosome].

Molekuliarnaia biologiia 20040101

Selective nitrosyl group transfer reaction to cytidine using oligonucleotides bearing S-nitrosothioguanosine.

Nucleic acids symposium series (2004) 20040101

Efficient syntheses of [2-(15)N]guanosine and 2'-deoxy[2-(15)N]guanosine derivatives.

Nucleic acids symposium series (2004) 20040101

Synthesis and base recognition ability of oligoribonucleotides incorporating 2'-O-methyl-3-deazaguanosine.

Nucleic acids symposium series (2004) 20040101

Design of 2'-O-Me RNA/ENA chimera oligonucleotides to induce exon skipping in dystrophin pre-mRNA.

Nucleic acids symposium series (2004) 20040101

Cigarette smoking as a risk factor of coronary artery disease and its effects on platelet function.

Tobacco induced diseases 20040101

Cloning and characterization of Xen-dorphin prohormone from Xenopus laevis: a new opioid-like prohormone distinct from proenkephalin and prodynorphin.

The Journal of biological chemistry 20031226

Identification of Drosophila neuropeptide receptors by G protein-coupled receptors-beta-arrestin2 interactions.

The Journal of biological chemistry 20031226

A new route to 2'-O-alkyl-2-thiouridine derivatives via 4-O-protection of the uracil base and hybridization properties of oligonucleotides incorporating these modified nucleoside derivatives.

The Journal of organic chemistry 20031226

Thermodynamic characterization of the binding of activator of G protein signaling 3 (AGS3) and peptides derived from AGS3 with G alpha i1.

The Journal of biological chemistry 20031219

Guanosine promotes myelination and functional recovery in chronic spinal injury.

Neuroreport 20031219

Direct activation by dopamine of recombinant human 5-HT1A receptors: comparison with human 5-HT2C and 5-HT3 receptors.

Synapse (New York, N.Y.) 20031215

Identification of relaxin-3/INSL7 as a ligand for GPCR142.

The Journal of biological chemistry 20031212

Identification of relaxin-3/INSL7 as an endogenous ligand for the orphan G-protein-coupled receptor GPCR135.

The Journal of biological chemistry 20031212

The [35S]GTPgammaS binding assay: approaches and applications in pharmacology.

Life sciences 20031212

Water-mediated association provides an ion pair receptor.

Journal of the American Chemical Society 20031210

C-type natriuretic peptide decreases soluble guanylate cyclase levels by activating the proteasome pathway.

Biochimica et biophysica acta 20031207

Chronic treatment with interleukin-1beta attenuates contractions by decreasing the activities of CPI-17 and MYPT-1 in intestinal smooth muscle.

The Journal of biological chemistry 20031205

Direct observation of G-protein binding to the human delta-opioid receptor using plasmon-waveguide resonance spectroscopy.

The Journal of biological chemistry 20031205

MANT-substituted guanine nucleotides: a novel class of potent adenylyl cyclase inhibitors.

Life sciences 20031205

Identification of surrogate ligands for orphan G protein-coupled receptors.

Life sciences 20031205

Design of photoactivated DNA oxidizing agents: synthesis and study of photophysical properties and DNA interactions of novel viologen-linked acridines.

Chemistry (Weinheim an der Bergstrasse, Germany) 20031205

Functional consequences of an in vivo mutation in exon 10 of the human GLUT1 gene.

FEBS letters 20031204

Silencing effect of CpG island hypermethylation and histone modifications on O6-methylguanine-DNA methyltransferase (MGMT) gene expression in human cancer.

Oncogene 20031204

Supramolecular helices via self-assembly of 8-oxoguanosines.

Journal of the American Chemical Society 20031203

SSR181507, a dopamine D(2) receptor antagonist and 5-HT(1A) receptor agonist. I: Neurochemical and electrophysiological profile.

Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20031201

Site of action of the general anesthetic propofol in muscarinic M1 receptor-mediated signal transduction.

The Journal of pharmacology and experimental therapeutics 20031201

Comparison of [Dmt1]DALDA and DAMGO in binding and G protein activation at mu, delta, and kappa opioid receptors.

The Journal of pharmacology and experimental therapeutics 20031201

Neuropeptide Y Y4 receptor homodimers dissociate upon agonist stimulation.

The Journal of pharmacology and experimental therapeutics 20031201

(-)-PHCCC, a positive allosteric modulator of mGluR4: characterization, mechanism of action, and neuroprotection.

Neuropharmacology 20031201

An IQGAP-like protein is involved in actin assembly together with Cdc42 in the sea urchin egg.

Cell motility and the cytoskeleton 20031201

Evidence for protein kinase C-mediated activation of Rho-kinase in a porcine model of coronary artery spasm.

Arteriosclerosis, thrombosis, and vascular biology 20031201

A point mutation uncouples transducin-alpha from the photoreceptor RGS and effector proteins.

Journal of neurochemistry 20031201

An optimized approach to study endocannabinoid signaling: evidence against constitutive activity of rat brain adenosine A1 and cannabinoid CB1 receptors.

British journal of pharmacology 20031201

The ability to form full-length intron RNA circles is a general property of nuclear group I introns.

RNA (New York, N.Y.) 20031201

Neuroprotective effect of adenine on purkinje cell survival in rat cerebellar primary cultures.

Journal of neuroscience research 20031201

Rat brain guanosine binding site. Biological studies and pseudo-receptor construction.

Bioorganic & medicinal chemistry 20031201

Allosteric enhancers of A1 adenosine receptors increase receptor-G protein coupling and counteract Guanine nucleotide effects on agonist binding.

Molecular pharmacology 20031201

Expression and regulation of phospholipase D isoenzymes in human melanoma cells and primary melanocytes.

Melanoma research 20031201

Effects of phosphodiesterase inhibitors on oesophageal neuromuscular functions.

Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society 20031201

[One base deletion of the alpha(1,4) galactosyltransferase gene responsible for p phenotype].

Zhonghua yi xue yi chuan xue za zhi = Zhonghua yixue yichuanxue zazhi = Chinese journal of medical genetics 20031201

Cyclic GMP protein kinase activity is reduced in thyroxine-induced hypertrophic cardiac myocytes.

Clinical and experimental pharmacology & physiology 20031201

DNA lesions derived from the site selective oxidation of Guanine by carbonate radical anions.

Chemical research in toxicology 20031201

Reduced expression of a novel mu-opioid receptor (MOR) subtype MOR-1B in CXBK mice: implications of MOR-1B in the expression of MOR-mediated responses.

The European journal of neuroscience 20031201

Molecular and biochemical analyses of OsRab7, a rice Rab7 homolog.

Plant & cell physiology 20031201

Repeated cocaine administration changes the function and subcellular distribution of adenosine A1 receptor in the rat nucleus accumbens.

Journal of neurochemistry 20031201

Non-genomic modulation of dopamine release by bisphenol-A in PC12 cells.

Journal of neurochemistry 20031201

Synthesis and conformational analysis of a locked analogue of carbovir built on a bicyclo[3.1.0]hex-2-enyl template.

Nucleosides, nucleotides & nucleic acids 20031201

Efficacy of methylenecyclopropane analogs of nucleosides against herpesvirus replication in vitro.

Nucleosides, nucleotides & nucleic acids 20031201

Lack of mu-opioid receptor-mediated G-protein activation in the spinal cord of mice lacking Exon 1 or Exons 2 and 3 of the MOR-1 gene.

Journal of pharmacological sciences 20031201

Guanosine 3',5'-cyclic monophosphate: a tapeworm-secreted signal molecule communicating with the rat host's small intestine.

The Journal of parasitology 20031201

Conformational states of the corticotropin releasing factor 1 (CRF1) receptor: detection, and pharmacological evaluation by peptide ligands.

Peptides 20031201

Functional properties of Pfr(Tic)amide and BIBP3226 at human neuropeptide FF2 receptors.

Peptides 20031201

Defective human MutY phosphorylation exists in colorectal cancer cell lines with wild-type MutY alleles.

The Journal of biological chemistry 20031128

Cell-specific behavior of P2X7 receptors in mouse parotid acinar and duct cells.

The Journal of biological chemistry 20031128

A novel ergot alkaloid as a 5-HT(1A) inhibitor produced by Dicyma sp.

Journal of medicinal chemistry 20031120

Formation of 13C-, 15N-, and 18O-labeled guanidinohydantoin from guanosine oxidation with singlet oxygen. Implications for structure and mechanism.

Journal of the American Chemical Society 20031119

Advances toward new antidepressants beyond SSRIs: 1-aryloxy-3-piperidinylpropan-2-ols with dual 5-HT1A receptor antagonism/SSRI activities. Part 3.

Bioorganic & medicinal chemistry letters 20031117

Urinary excretion of three nucleic acid oxidation adducts and isoprostane F(2)alpha measured by liquid chromatography-mass spectrometry in smokers, ex-smokers, and nonsmokers.

Free radical biology & medicine 20031115

Parallel coiled-coil association of the RhoA-binding domain in Rho-kinase.

The Journal of biological chemistry 20031114

Superoxide generation mediated by 8-nitroguanosine, a highly redox-active nucleic acid derivative.

Biochemical and biophysical research communications 20031114

Selective binding of monovalent cations to the stacking G-quartet structure formed by guanosine 5'-monophosphate: a solid-state NMR study.

Journal of the American Chemical Society 20031112

Pre-steady-state analysis of the nucleoside hydrolase of Trypanosoma vivax. Evidence for half-of-the-sites reactivity and rate-limiting product release.

Biochemistry 20031111

Effect of the oxidized guanosine lesions spiroiminodihydantoin and guanidinohydantoin on proofreading by Escherichia coli DNA polymerase I (Klenow fragment) in different sequence contexts.

Biochemistry 20031111

Differential regulation of exocytotic fusion and granule-granule fusion in eosinophils by Ca2+ and GTP analogs.

The Journal of biological chemistry 20031107

Compound exocytosis and cumulative fusion in eosinophils.

The Journal of biological chemistry 20031107

Determination of the catalytic parameters of the N-terminal half of Escherichia coli ribonuclease E and the identification of critical functional groups in RNA substrates.

The Journal of biological chemistry 20031107

Anti-mu opioid antiserum against the third external loop of the cloned mu-opioid receptor acts as a mu receptor neutral antagonist.

Brain research. Molecular brain research 20031106

8-Methylguanosine: a powerful Z-DNA stabilizer.

Journal of the American Chemical Society 20031105

Physiology and pathophysiology of vascular signaling controlled by guanosine 3',5'-cyclic monophosphate-dependent protein kinase [corrected].

Circulation 20031104

Interactions between epithelial nitric oxide signaling and phosphodiesterase activity in Drosophila.

American journal of physiology. Cell physiology 20031101

Decrease in intracellular superoxide sensitizes Bcl-2-overexpressing tumor cells to receptor and drug-induced apoptosis independent of the mitochondria.

Cell death and differentiation 20031101

Up-regulation of spinal muscarinic receptors and increased antinociceptive effect of intrathecal muscarine in diabetic rats.

The Journal of pharmacology and experimental therapeutics 20031101

Ca2+ responses in Chinese hamster ovary-K1 cells demonstrate an atypical pattern of ligand-induced 5-HT1A receptor activation.

The Journal of pharmacology and experimental therapeutics 20031101

N-terminal modifications leading to peptide ORL1 partial agonists and antagonists.

The journal of peptide research : official journal of the American Peptide Society 20031101

Selective gamma-hydroxybutyric acid receptor ligands increase extracellular glutamate in the hippocampus, but fail to activate G protein and to produce the sedative/hypnotic effect of gamma-hydroxybutyric acid.

Journal of neurochemistry 20031101

Guanylyl cyclases, nitric oxide, natriuretic peptides, and airway smooth muscle function.

American journal of physiology. Lung cellular and molecular physiology 20031101

G-quartet self-assembly under osmotic pressure: remote control by vesicle shrinking rather than stress.

Chirality 20031101

Plasma membrane-associated nucleoside diphosphate kinase (nm23) in the heart is regulated by beta-adrenergic signaling.

British journal of pharmacology 20031101

Lidocaine enhances Galphai protein function.

Anesthesiology 20031101

The Toll-like receptor 7 (TLR7)-specific stimulus loxoribine uncovers a strong relationship within the TLR7, 8 and 9 subfamily.

European journal of immunology 20031101

Metabotropic glutamate receptor regulation of neuronal cell death.

Experimental neurology 20031101

Mycophenolate mofetil inhibits human Tenon fibroblast proliferation by guanosine depletion.

The British journal of ophthalmology 20031101

Basal nitric oxide modulates vascular effects of a peptide activating protease-activated receptor 2.

Cardiovascular research 20031101

Functional autoradiography of neuropeptide Y Y1 and Y2 receptor subtypes in rat brain using agonist stimulated [35S]GTPgammaS binding.

Journal of chemical neuroanatomy 20031101

Direct evidence for the up-regulation of spinal micro-opioid receptor function after repeated stimulation of kappa-opioid receptors in the mouse.

The European journal of neuroscience 20031101

Functional effects of deleting the coiled-coil motif in Escherichia coli elongation factor Ts.

European journal of biochemistry 20031101

Low molecular weight G-proteins of rho-family mediate relaxations to bradykinin in porcine coronary arteries.

Acta pharmacologica Sinica 20031101

MPP+ induces the endoplasmic reticulum stress response in rabbit brain involving activation of the ATF-6 and NF-kappaB signaling pathways.

Journal of neuropathology and experimental neurology 20031101

Specific gamma-hydroxybutyrate-binding sites but loss of pharmacological effects of gamma-hydroxybutyrate in GABA(B)(1)-deficient mice.

The European journal of neuroscience 20031101

Tuberous sclerosis complex: genetics to pathogenesis.

Pediatric neurology 20031101

Inhibition of Bacillus subtilis aprE expression by lincomycin at the posttranscriptional level through inhibition of ppGpp synthesis.

Journal of biochemistry 20031101

A novel Escherichia coli strain allows functional analysis of guanylate kinase drug resistance and sensitivity.

Analytical biochemistry 20031101

[Studies on chemical constituents of the mycelia from fermented culture of Flammulina velutipes].

Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20031101

Use of 13C as an indirect tag in 15N specifically labeled nucleosides. Syntheses of [8-13C-1,7,NH2-15N3]adenosine, -guanosine, and their deoxy analogues.

The Journal of organic chemistry 20031031

Labile iron pool: the main determinant of cellular response to oxidative stress.

Mutation research 20031029

Site-specific DNA transesterification by vaccinia topoisomerase: effects of benzo[alpha]pyrene-dA, 8-oxoguanine, 8-oxoadenine and 2-aminopurine modifications.

The Journal of biological chemistry 20031024

Dimers of class A G protein-coupled receptors function via agonist-mediated trans-activation of associated G proteins.

The Journal of biological chemistry 20031024

Functional annotation of the putative orphan Caenorhabditis elegans G-protein-coupled receptor C10C6.2 as a FLP15 peptide receptor.

The Journal of biological chemistry 20031024

Identification of a hexapeptide binding region in the nociceptin (ORL1) receptor by photo-affinity labelling with Ac-Arg-Bpa-Tyr-Arg-Trp-Arg-NH2.

Biochemical and biophysical research communications 20031024

Helix 8 of the leukotriene B4 receptor is required for the conformational change to the low affinity state after G-protein activation.

The Journal of biological chemistry 20031017

CP-481,715, a potent and selective CCR1 antagonist with potential therapeutic implications for inflammatory diseases.

The Journal of biological chemistry 20031017

Evidence for an intracellular ADP-ribosyl cyclase/NAD+-glycohydrolase in brain from CD38-deficient mice.

The Journal of biological chemistry 20031017

Cytosolic Arl2 is complexed with cofactor D and protein phosphatase 2A.

The Journal of biological chemistry 20031017

Selective fluorescence quenching of 2,3-diazabicyclo[2.2.2]oct-2-ene by nucleotides.

Organic letters 20031016

Macrocyclic amines as catalysts of the hydrolysis of the triphosphate bridge of the mRNA 5'-cap structure.

Organic & biomolecular chemistry 20031007

Synthesis of S6-(2,4-dinitrophenyl)-6-thioguanosine phosphoramidite and its incorporation into oligoribonucleotides.

Bioorganic & medicinal chemistry letters 20031006

Progressive alterations in global and GC-rich DNA methylation during tumorigenesis.

Toxicological sciences : an official journal of the Society of Toxicology 20031001

GTP gamma S increases Nav1.8 current in small-diameter dorsal root ganglia neurons.

Experimental brain research 20031001

Evidence for multiple distinctly localized adenylyl cyclase isoforms in mammalian spermatozoa.

Molecular reproduction and development 20031001

Methods for the design and analysis of oligodeoxynucleotide-based DNA (cytosine-5) methyltransferase inhibitors.

Analytical biochemistry 20031001

Biochemical evidence for a P2Y-like receptor in Tetrahymena thermophila.

Journal of comparative physiology. A, Neuroethology, sensory, neural, and behavioral physiology 20031001

Pharmacological characterization and identification of amino acids involved in the positive modulation of metabotropic glutamate receptor subtype 2.

Molecular pharmacology 20031001

Ki16425, a subtype-selective antagonist for EDG-family lysophosphatidic acid receptors.

Molecular pharmacology 20031001

Contribution of active site residues to the activity and thermal stability of ribonuclease Sa.

Protein science : a publication of the Protein Society 20031001

Involvement of rpoS in the survival of Escherichia coli in the viable but non-culturable state.

Environmental microbiology 20031001

Insulin and lysophosphatidylcholine synergistically stimulate NO-dependent cGMP production in human endothelial cells.

Diabetic medicine : a journal of the British Diabetic Association 20031001

Identification of a ribavirin-resistant NS5B mutation of hepatitis C virus during ribavirin monotherapy.

Hepatology (Baltimore, Md.) 20031001

Comparative analysis of functional assays for characterization of agonist ligands at G protein-coupled receptors.

Journal of biomolecular screening 20031001

Inhibition of the group I ribozyme splicing by NADP+.

Molecular and cellular biochemistry 20031001

Implication of adenosine 3',5'-cyclic monophosphate, guanosine 3',5'-cyclic monophosphate, adenosine 5'-mono-, di-, and triphosphate and fructose-2,6-bisphosphate in the regulation of the glycolytic pathway in relation to the gametogenic cycle in the mussel mytilus galloprovincialis Lmk.

Molecular and cellular biochemistry 20031001

G3139 (oblimersen) may inhibit prostate cancer cell growth in a partially bis-CpG-dependent non-antisense manner.

Molecular cancer therapeutics 20031001

Expression of nitric oxide synthase isoforms in the human placenta is not altered by labor.

Endocrine journal 20031001

Cannabinoid receptor and WIN 55 212-2-stimulated [35S]-GTPgammaS binding in the brain of mu-, delta- and kappa-opioid receptor knockout mice.

The European journal of neuroscience 20031001

Hypocretin-1 causes G protein activation and increases ACh release in rat pons.

The European journal of neuroscience 20031001

Review of the antiproliferative properties of mycophenolate mofetil in non-immune cells.

International journal of clinical pharmacology and therapeutics 20031001

Development of displacement binding and GTPgammaS scintillation proximity assays for the identification of antagonists of the micro-opioid receptor.

Assay and drug development technologies 20031001

Neurodegeneration in striatum induced by the mitochondrial toxin 3-nitropropionic acid: role of matrix metalloproteinase-9 in early blood-brain barrier disruption?

The Journal of neuroscience : the official journal of the Society for Neuroscience 20030924

Constitutive activation of CCR5 and CCR2 induced by conformational changes in the conserved TXP motif in transmembrane helix 2.

The Journal of biological chemistry 20030919

Oxidized human neuroglobin acts as a heterotrimeric Galpha protein guanine nucleotide dissociation inhibitor.

The Journal of biological chemistry 20030919

Role of ADP-ribosylation factor 6 (ARF6) in gastric acid secretion.

The Journal of biological chemistry 20030919

Essential role of histidine 84 in elongation factor Tu for the chemical step of GTP hydrolysis on the ribosome.

Journal of molecular biology 20030919

The role of cGMP in the regulation of rabbit airway ciliary beat frequency.

The Journal of physiology 20030915

Involvement of NMDA receptors and L-arginine-nitric oxide pathway in the antidepressant-like effects of zinc in mice.

Behavioural brain research 20030915

Equilibrative nucleoside transporter family members from Leishmania donovani are electrogenic proton symporters.

The Journal of biological chemistry 20030912

Lipophilic G-quadruplexes are self-assembled ion pair receptors, and the bound anion modulates the kinetic stability of these complexes.

Journal of the American Chemical Society 20030910

Amyloid precursor protein carboxy-terminal fragments modulate G-proteins and adenylate cyclase activity in Alzheimer's disease brain.

Brain research. Molecular brain research 20030910

Gene transfer of human guanosine 5'-triphosphate cyclohydrolase I restores vascular tetrahydrobiopterin level and endothelial function in low renin hypertension.

Circulation 20030909

Differential activation of 'social' and 'solitary' variants of the Caenorhabditis elegans G protein-coupled receptor NPR-1 by its cognate ligand AF9.

The Journal of biological chemistry 20030905

Inositol pyrophosphates mediate chemotaxis in Dictyostelium via pleckstrin homology domain-PtdIns(3,4,5)P3 interactions.

Cell 20030905

Protection of the amino group of adenosine and guanosine derivatives by elaboration into a 2,5-dimethylpyrrole moiety.

Organic letters 20030904

Group II mGlu receptor activation suppresses norepinephrine release in the ventral hippocampus and locomotor responses to acute ketamine challenge.

Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20030901

Functional coupling between heterologously expressed dopamine D(2) receptors and KCNQ channels.

Pflugers Archiv : European journal of physiology 20030901

Inhibition of GTP-dependent vesicle trafficking impairs internalization of plasmalemmal eNOS and cellular nitric oxide production.

Journal of cell science 20030901

Somatic embryogenesis in loblolly pine (Pinus taeda L.): improving culture initiation with abscisic acid and silver nitrate.

Plant cell reports 20030901

Hg2+ signaling in trout hepatoma (RTH-149) cells: involvement of Ca2+-induced Ca2+ release.

Cell calcium 20030901

Activation by N-acetyl-L-aspartate of acutely dissociated hippocampal neurons in rats via metabotropic glutamate receptors.

Epilepsia 20030901

Comparison of hippocampal G protein activation by 5-HT(1A) receptor agonists and the atypical antipsychotics clozapine and S16924.

Naunyn-Schmiedeberg's archives of pharmacology 20030901

Purine and pyrimidine metabolites in children's urine.

Clinica chimica acta; international journal of clinical chemistry 20030901

The blockade of formyl peptide-induced respiratory burst by 2',5'-dihydroxy-2-furfurylchalcone involves phospholipase D signaling in neutrophils.

Naunyn-Schmiedeberg's archives of pharmacology 20030901

Charge distribution in 7-methylguanine regarding cation-pi interaction with protein factor eIF4E.

Biophysical journal 20030901

L-arginine-induced relaxation of the internal anal sphincter is not mediated by nitric oxide.

The British journal of surgery 20030901

The novel nucleoside transport system exhibited by NB4 cells, csg, transports deoxyguanosine analogues, including ara-G.

Biochemical pharmacology 20030901

Functional calcium coupling with the human metabotropic glutamate receptor subtypes 2 and 4 by stable co-expression with a calcium pathway facilitating G-protein chimera in Chinese hamster ovary cells.

Biochemical pharmacology 20030901

Sevoflurane inhibits guanosine 5'-[gamma-thio]triphosphate-stimulated, Rho/Rho-kinase-mediated contraction of isolated rat aortic smooth muscle.

Anesthesiology 20030901

Expression of EGFP-amino-tagged human mu opioid receptor in Drosophila Schneider 2 cells: a potential expression system for large-scale production of G-protein coupled receptors.

Protein expression and purification 20030901

Partial agonist behaviour depends upon the level of nociceptin/orphanin FQ receptor expression: studies using the ecdysone-inducible mammalian expression system.

British journal of pharmacology 20030901

Molecular mechanisms of ligand-receptor interactions in transmembrane domain V of the alpha2A-adrenoceptor.

British journal of pharmacology 20030901

An insight into the phenomena involved in a multiple-function stationary phase for the capillary electrochromatographic separation of 2'-, 3'-, and 5'-monophosphorylated nucleoside isomers.

Electrophoresis 20030901

Current and future therapy for chronic hepatitis C virus liver disease.

Current drug targets. Infectious disorders 20030901

Extracellular nucleotides and nucleosides induce proliferation and increase nucleoside transport in human glioma cell lines.

Journal of neuro-oncology 20030901

Photodynamic activity of monocationic and non-charged methoxyphenylporphyrin derivatives in homogeneous and biological media.

Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology 20030901

Characterization of YopT effects on Rho GTPases in Yersinia enterocolitica-infected cells.

The Journal of biological chemistry 20030829

Functional analysis of an inosine-guanosine transporter from Leishmania donovani. The role of conserved residues, aspartate 389 and arginine 393.

The Journal of biological chemistry 20030829

Selective interactions between helix VIII of the human mu-opioid receptors and the C terminus of periplakin disrupt G protein activation.

The Journal of biological chemistry 20030829

Antioxidant compounds from the leaves of Peucedanum japonicum thunb.

Journal of agricultural and food chemistry 20030827

Reduced G(i) and G(o) protein function in the rat nucleus accumbens attenuates sensorimotor gating deficits.

Brain research 20030822

Efficient one-step Suzuki arylation of unprotected halonucleosides, using water-soluble palladium catalysts.

The Journal of organic chemistry 20030822

The design and synthesis of guanosine compounds with in vitro activity against the colon cancer cell line SW480: non-taxane derived mimics of taxol?

Bioorganic & medicinal chemistry letters 20030818

Three kinds of current in response to substance P in bullfrog DRG neurons.

Brain research 20030815

The hydantoin lesions formed from oxidation of 7,8-dihydro-8-oxoguanine are potent sources of replication errors in vivo.

Biochemistry 20030812

Hyaluronan-mediated CD44 interaction with RhoGEF and Rho kinase promotes Grb2-associated binder-1 phosphorylation and phosphatidylinositol 3-kinase signaling leading to cytokine (macrophage-colony stimulating factor) production and breast tumor progression.

The Journal of biological chemistry 20030808

Agonist-induced formation of opioid receptor-G protein-coupled receptor kinase (GRK)-G beta gamma complex on membrane is required for GRK2 function in vivo.

The Journal of biological chemistry 20030808

Sequence specific DNA binding of Ets-1 transcription factor: molecular dynamics study on the Ets domain--DNA complexes.

Journal of molecular biology 20030808

Selectivity of purine alkylation by a quinone methide. Kinetic or thermodynamic control?

The Journal of organic chemistry 20030808

A putative consensus sequence for the nucleotide-binding site of annexin A6.

Biochemistry 20030805

Light-mediated activation of Rac-1 in photoreceptor outer segments.

Current biology : CB 20030805

Characterization of the binding of [3H][Dmt1]H-Dmt-D-Arg-Phe-Lys-NH2, a highly potent opioid peptide.

The Journal of pharmacology and experimental therapeutics 20030801

Diurnal variation in the renal excretion of modified RNA catabolites in humans.

Clinical science (London, England : 1979) 20030801

Chronic fluoxetine differentially affects 5-hydroxytryptamine (2A) receptor signaling in frontal cortex, oxytocin- and corticotropin-releasing factor-containing neurons in rat paraventricular nucleus.

The Journal of pharmacology and experimental therapeutics 20030801

Functional melatonin receptors in rat ovaries at various stages of the estrous cycle.

The Journal of pharmacology and experimental therapeutics 20030801

IIGP1, an interferon-gamma-inducible 47-kDa GTPase of the mouse, showing cooperative enzymatic activity and GTP-dependent multimerization.

The Journal of biological chemistry 20030801

Entrapment of Rho ADP-ribosylated by Clostridium botulinum C3 exoenzyme in the Rho-guanine nucleotide dissociation inhibitor-1 complex.

The Journal of biological chemistry 20030801

Dissociation of cGMP accumulation and relaxation in myometrial smooth muscle: effects of S-nitroso-N-acetylpenicillamine and 3-morpholinosyndonimine.

Cellular signalling 20030801

Testosterone stimulates intracellular calcium release and mitogen-activated protein kinases via a G protein-coupled receptor in skeletal muscle cells.

Endocrinology 20030801

Urinary 8-hydroxydeoxyguanosine and its analogs as DNA marker of oxidative stress: development of an ELISA and measurement in both bladder and prostate cancers.

Clinica chimica acta; international journal of clinical chemistry 20030801

Painful inflammation-induced increase in mu-opioid receptor binding and G-protein coupling in primary afferent neurons.

Molecular pharmacology 20030801

Differential involvement of intracellular domains of the rat NTS1 neurotensin receptor in coupling to G proteins: a molecular basis for agonist-directed trafficking of receptor stimulus.

Molecular pharmacology 20030801

Tiotidine, a histamine H2 receptor inverse agonist that binds with high affinity to an inactive G-protein-coupled form of the receptor. Experimental support for the cubic ternary complex model.

Molecular pharmacology 20030801

Use of nucleotide analogs by class I and class II CCA-adding enzymes (tRNA nucleotidyltransferase): deciphering the basis for nucleotide selection.

RNA (New York, N.Y.) 20030801

G-protein activation decreases isoflurane inhibition of N-type Ba2+ currents.

Anesthesiology 20030801

Pathways for the regulation of interferon-gamma-inducible genes by iron in human monocytic cells.

Journal of leukocyte biology 20030801

Transduction of the liver with activated Akt normalizes portal pressure in cirrhotic rats.

Gastroenterology 20030801

Pressure effects on the GTPase activity of brain membrane G proteins of deep-living marine fishes.

Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology 20030801

Lignan and megastigmane glycosides from Sauropus androgynus.

Phytochemistry 20030801

Expression and G-protein coupling of mu-opioid receptors in the spinal cord and dorsal root ganglia of polyarthritic rats.

Neuropeptides 20030801

Phosphodiesterases in the vascular system.

Journal of smooth muscle research = Nihon Heikatsukin Gakkai kikanshi 20030801

Essential role for the peroxiredoxin Prdx1 in erythrocyte antioxidant defence and tumour suppression.

Nature 20030731

Identification and characterisation of high affinity nucleoside and nucleobase transporters in Toxoplasma gondii.

International journal for parasitology 20030730

Novel guanosine-cytidine dinucleoside that self-assembles into a trimeric supramolecule.

Organic letters 20030724

Advances Toward new antidepressants beyond SSRIs: 1-aryloxy-3-piperidinylpropan-2-ols with dual 5-HT(1A) receptor antagonism/SSRI activities. Part 2.

Bioorganic & medicinal chemistry letters 20030721

Evidence for the involvement of G-proteins in the generation of the slow poststimulus afterdepolarisation (sADP) induced by muscarinic receptor activation in rat olfactory cortical neurones in vitro.

Brain research 20030718

Glutamate receptors in the terminal nerve gonadotropin-releasing hormone neurons of the dwarf gourami (teleost).

Neuroscience letters 20030717

l-2',3'-Didehydro-2',3'-dideoxy-3'-fluoronucleosides: synthesis, anti-HIV activity, chemical and enzymatic stability, and mechanism of resistance.

Journal of medicinal chemistry 20030717

Non-hydrolyzable analog of GTP induces activity of Na+ channels via disassembly of cortical actin cytoskeleton.

FEBS letters 20030717

Excitatory effects of orexin-A on nucleus tractus solitarius neurons are mediated by phospholipase C and protein kinase C.

The Journal of neuroscience : the official journal of the Society for Neuroscience 20030716

Role of tissue transglutaminase in GTP depletion-induced apoptosis of insulin-secreting (HIT-T15) cells.

Biochemical pharmacology 20030715

Differential translation of TOP mRNAs in rapamycin-treated human B lymphocytes.

Biochimica et biophysica acta 20030709

Cholesterol-dependent association of caveolin-1 with the transducin alpha subunit in bovine photoreceptor rod outer segments: disruption by cyclodextrin and guanosine 5'-O-(3-thiotriphosphate).

Biochemistry 20030708

The myristoylated amino terminus of Galpha(i)(1) plays a critical role in the structure and function of Galpha(i)(1) subunits in solution.

Biochemistry 20030708

Influence of cytosolic AGS3 on receptor--G protein coupling.

Biochemistry 20030708

Platinum(II)-based coordination compounds as nucleic acid labeling reagents: synthesis, reactivity, and applications in hybridization assays.

Chembiochem : a European journal of chemical biology 20030707

Curing of foot-and-mouth disease virus from persistently infected cells by ribavirin involves enhanced mutagenesis.

Virology 20030705

Chronically administered guanosine is anticonvulsant, amnesic and anxiolytic in mice.

Brain research 20030704

Synthesis and characterization of NESS 0327: a novel putative antagonist of the CB1 cannabinoid receptor.

The Journal of pharmacology and experimental therapeutics 20030701

Studies of micro-, kappa-, and delta-opioid receptor density and G protein activation in the cortex and thalamus of monkeys.

The Journal of pharmacology and experimental therapeutics 20030701

Activation of phosphoinositide 3-kinase by D2 receptor prevents apoptosis in dopaminergic cell lines.

The Biochemical journal 20030701

beta-Funaltrexamine, a gauge for the recognition site of wildtype and mutant H297Q mu-opioid receptors.

Synapse (New York, N.Y.) 20030701

Arsenate reduction in human erythrocytes and rats--testing the role of purine nucleoside phosphorylase.

Toxicological sciences : an official journal of the Society of Toxicology 20030701

Regulation of early endocytic vesicle motility and fission in a reconstituted system.

Journal of cell science 20030701

2-Alkylthio-substituted platelet P2Y12 receptor antagonists reveal pharmacological identity between the rat brain Gi-linked ADP receptors and P2Y12.

Neuropharmacology 20030701

Pharmacological characterization of the human P2Y13 receptor.

Molecular pharmacology 20030701

Effect of halothane on the guanosine 5' triphosphate binding activity of G-protein alphai subunits.

Anesthesiology 20030701

The avilamycin resistance determinants AviRa and AviRb methylate 23S rRNA at the guanosine 2535 base and the uridine 2479 ribose.

Molecular microbiology 20030701

Binding and GTPgammaS autoradiographic analysis of preproorphanin precursor peptide products at the ORL1 and opioid receptors.

Journal of chemical neuroanatomy 20030701

Photochemical cross-linking of Escherichia coli Fpg protein to DNA duplexes containing phenyl(trifluoromethyl)diazirine groups.

European journal of biochemistry 20030701

Regulation of eosinophil apoptosis by nitric oxide: Role of c-Jun-N-terminal kinase and signal transducer and activator of transcription 5.

The Journal of allergy and clinical immunology 20030701

Estrogen-dependent alterations in D2/D3-induced G protein activation in cocaine-sensitized female rats.

Journal of neurochemistry 20030701

The effect of nitric oxide on the permeability of nasal epithelial cells from healthy and asthmatic donors.

Medical science monitor : international medical journal of experimental and clinical research 20030701

Efficacy of 8-bromoguanosine against murine cutaneous leishmaniasis induced with Leishmania amazonensis.

Chemotherapy 20030701

Binding characteristics of [3H]14-methoxymetopon, a high affinity mu-opioid receptor agonist.

The European journal of neuroscience 20030701

Control of rRNA expression by small molecules is dynamic and nonredundant.

Molecular cell 20030701

Increased endothelin: nitric oxide ratio is associated with erythropoietin-induced hypertension in hemodialysis patients.

Renal failure 20030701

['Magic spot' synthase in chloroplasts].

Seikagaku. The Journal of Japanese Biochemical Society 20030701

Soluble guanylyl cyclase: physiological role as an NO receptor and the potential molecular target for therapeutic application.

Clinical chemistry and laboratory medicine 20030701

Cloning, heterologous expression, and in situ characterization of the first high affinity nucleobase transporter from a protozoan.

The Journal of biological chemistry 20030627

Co-expression of the beta2-adrenoceptor and dopamine D1-receptor with Gsalpha proteins in Sf9 insect cells: limitations in comparison with fusion proteins.

Biochimica et biophysica acta 20030627

Signal transduction in the visual cascade involves specific lipid-protein interactions.

The Journal of biological chemistry 20030620

Pharmacological analysis of a dopamine D(2Short):G(alphao) fusion protein expressed in Sf9 cells.

FEBS letters 20030619

Direct detection of potassium cations bound to G-quadruplex structures by solid-state 39K NMR at 19.6 T.

Journal of the American Chemical Society 20030618

Unexpected inhibition of S-adenosyl-L-homocysteine hydrolase by a guanosine nucleoside.

Bioorganic & medicinal chemistry letters 20030616

Synthesis and characterization of platinum diimine bis(acetylide) complexes containing easily derivatizable aryl acetylide ligands.

Inorganic chemistry 20030616

Induction of apoptosis in IL-3-dependent hematopoietic cell lines by guanine nucleotide depletion.

Blood 20030615

Nongenomic glucocorticoid inhibition via endocannabinoid release in the hypothalamus: a fast feedback mechanism.

The Journal of neuroscience : the official journal of the Society for Neuroscience 20030615

Crystallographic characterization of an exocyclic DNA adduct: 3,N4-etheno-2'-deoxycytidine in the dodecamer 5'-CGCGAATTepsilonCGCG-3'.

Journal of molecular biology 20030613

Distinct effects of amantadine and memantine on dopaminergic transmission in the rat striatum.

Neuroscience letters 20030612

Expression and modulation of an invertebrate presynaptic calcium channel alpha1 subunit homolog.

The Journal of biological chemistry 20030606

Activation of in situ tissue transglutaminase by intracellular reactive oxygen species.

Biochemical and biophysical research communications 20030606

The effect of ribavirin and IMPDH inhibitors on hepatitis C virus subgenomic replicon RNA.

Virology 20030605

Advances toward new antidepressants beyond SSRIs: 1-aryloxy-3-piperidinylpropan-2-ols with dual 5-HT1A receptor antagonism/SSRI activities. Part 1.

Bioorganic & medicinal chemistry letters 20030602

Acid-base and metal ion binding properties of guanylyl(3'-->5')guanosine (GpG-) and 2'-deoxyguanylyl(3'-->5')-2'-deoxyguanosine [d(GpG)-] in aqueous solution.

Inorganic chemistry 20030602

Crystal structure of tRNA(m1G37)methyltransferase: insights into tRNA recognition.

The EMBO journal 20030602

Two novel and selective nonimidazole histamine H3 receptor antagonists A-304121 and A-317920: I. In vitro pharmacological effects.

The Journal of pharmacology and experimental therapeutics 20030601

Prolactin releasing peptide has high affinity and efficacy at neuropeptide FF2 receptors.

The Journal of pharmacology and experimental therapeutics 20030601

Dissimilar pharmacological responses by a new series of imidazoline derivatives at precoupled and ligand-activated alpha 2A-adrenoceptor states: evidence for effector pathway-dependent differential antagonism.

The Journal of pharmacology and experimental therapeutics 20030601

Dopamine-mediated inhibition of renal Na,K-ATPase is reduced by insulin.

Hypertension (Dallas, Tex. : 1979) 20030601

Native somatostatin sst2 and sst5 receptors functionally coupled to Gi/o-protein, but not to the serum response element in AtT-20 mouse tumour corticotrophs.

Naunyn-Schmiedeberg's archives of pharmacology 20030601

Ethanol consumption and serotonin-1A (5-HT1A) receptor function in heterozygous BDNF (+/-) mice.

Journal of neurochemistry 20030601

Heterologous mu-opioid receptor adaptation by repeated stimulation of kappa-opioid receptor: up-regulation of G-protein activation and antinociception.

Journal of neurochemistry 20030601

Established and emerging fluorescence-based assays for G-protein function: heterotrimeric G-protein alpha subunits and regulator of G-protein signaling (RGS) proteins.

Combinatorial chemistry & high throughput screening 20030601

Induction of antioxidative and antiapoptotic thioredoxin supports neuroprotective hypothesis of estrogen.

Endocrine 20030601

Control of signalling efficacy by palmitoylation of the rat Y1 receptor.

British journal of pharmacology 20030601

Functional characterization of a H+/nucleoside co-transporter (CaCNT) from Candida albicans, a fungal member of the concentrative nucleoside transporter (CNT) family of membrane proteins.

Yeast (Chichester, England) 20030601

SB-656104-A, a novel selective 5-HT7 receptor antagonist, modulates REM sleep in rats.

British journal of pharmacology 20030601

Gabapentin blocks L-type and P/Q-type Ca2+ channels involved in depolarization-stimulated nitric oxide synthase activity in primary cultures of neurons from mouse cerebral cortex.

Pharmaceutical research 20030601

Tumor-inhibiting platinum(II) complexes with aminoalcohol ligands: comparison of the mode of action by capillary electrophoresis and electrospray ionization-mass spectrometry.

Electrophoresis 20030601

Inactivation of platelet glycoprotein IIb/IIIa receptor by nitric oxide donor 3-morpholino-sydnonimine.

Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis 20030601

Melatonin exerts an antidepressant-like effect in the tail suspension test in mice: evidence for involvement of N-methyl-D-aspartate receptors and the L-arginine-nitric oxide pathway.

Neuroscience letters 20030529

Dioxolane guanosine 5'-triphosphate, an alternative substrate inhibitor of wild-type and mutant HIV-1 reverse transcriptase. Steady state and pre-steady state kinetic analyses.

The Journal of biological chemistry 20030523

Structure-activity relationships of dynorphin a analogues modified in the address sequence.

Journal of medicinal chemistry 20030522

Ionic states of substrates and transition state analogues at the catalytic sites of N-ribosyltransferases.

Biochemistry 20030520

Novel synthesis of 2'-O-methylguanosine.

Bioorganic & medicinal chemistry letters 20030519

Delayed expression of apoptosis in human lymphoma cells undergoing low-dose taxol-induced mitotic stress.

British journal of cancer 20030519

Serine 338 phosphorylation is dispensable for activation of c-Raf1.

The Journal of biological chemistry 20030516

Poly(ADP-ribose) polymerase-1 (PARP-1) is required in murine cell lines for base excision repair of oxidative DNA damage in the absence of DNA polymerase beta.

The Journal of biological chemistry 20030516

Extracellular conversion of guanine-based purines to guanosine specifically enhances astrocyte glutamate uptake.

Brain research 20030516

Ontogeny of GABA(B) receptor subunit expression and function in the rat spinal cord.

Brain research 20030516

Ca2+/calmodulin binds and dissociates K-RasB from membrane.

Biochemical and biophysical research communications 20030516

Effect of strain and sex on mu opioid receptor-mediated G-protein activation in rat brain.

Brain research bulletin 20030515

Crystal structures of the ribonuclease MC1 mutants N71T and N71S in complex with 5'-GMP: structural basis for alterations in substrate specificity.

Biochemistry 20030513

Positioning of mRNA codons with respect to 18S rRNA at the P and E sites of human ribosome.

Biochimica et biophysica acta 20030513

Recombinant antibodies to the small GTPase Rab6 as conformation sensors.

Science (New York, N.Y.) 20030509

Toward novel DNA binding metal complexes: structure and basic kinetic data of [M(9MeG)2(CH3OH)(CO)3]+(M = 99Tc, Re).

Inorganic chemistry 20030505

Promiscuous coupling at receptor-Galpha fusion proteins. The receptor of one covalent complex interacts with the alpha-subunit of another.

The Journal of biological chemistry 20030502

The vesicular monoamine content regulates VMAT2 activity through Galphaq in mouse platelets. Evidence for autoregulation of vesicular transmitter uptake.

The Journal of biological chemistry 20030502

Induction of vasorelaxation through activation of nitric oxide synthase in endothelial cells by brazilin.

European journal of pharmacology 20030502

A GC-box within the proximal promoter region of the rat cathepsin L gene activates transcription in Sertoli cells of sexually mature rats.

Biology of reproduction 20030501

Endogenous opioid peptides contribute to antinociceptive potency of intrathecal [Dmt1]DALDA.

The Journal of pharmacology and experimental therapeutics 20030501

Differential regulation of the human kappa opioid receptor by agonists: etorphine and levorphanol reduced dynorphin A- and U50,488H-induced internalization and phosphorylation.

The Journal of pharmacology and experimental therapeutics 20030501

An unusual form of the association binding kinetics of N-[3H]methylscopolamine to the split muscarinic M2trunk/M2tail receptor.

The Journal of pharmacology and experimental therapeutics 20030501

Functional differences between human formyl peptide receptor isoforms 26, 98, and G6.

Naunyn-Schmiedeberg's archives of pharmacology 20030501

Mycophenolic acid inhibits activation of inducible nitric oxide synthase in rodent fibroblasts.

Clinical and experimental immunology 20030501

Identification of the yeast gene encoding the tRNA m1G methyltransferase responsible for modification at position 9.

RNA (New York, N.Y.) 20030501

Characterization and maturational differences of melatonin binding sites in the masu salmon brain.

General and comparative endocrinology 20030501

The lectin jacalin induces phosphorylation of ERK and JNK in CD4+ T cells.

Journal of leukocyte biology 20030501

Important amino acids for the function of the human MT1 melatonin receptor.

Biochemical pharmacology 20030501

Antiguanosine antibodies in murine and human lupus have the internal image of G-binding proteins.

The Journal of rheumatology 20030501

Slow inhibition of N-type calcium channels with GTP gamma S reflects the basal G protein-GDP turnover rate.

Pflugers Archiv : European journal of physiology 20030501

Ontogenetic development of cannabinoid receptor expression and signal transduction functionality in the human brain.

The European journal of neuroscience 20030501

Dihydroergotamine and its metabolite, 8'-hydroxy-dihydroergotamine, as 5-HT1A receptor agonists in the rat brain.

British journal of pharmacology 20030501

Involvement of H2O2 in superoxide-dismutase-induced enhancement of endothelium-dependent relaxation in rabbit mesenteric resistance artery.

British journal of pharmacology 20030501

Two lead drug designs based on chloramphenicol as the parent structure, which express alkylation activity with potential for clinical applications.

The Journal of pharmacy and pharmacology 20030501

Role of ascorbic acid in the modulation of inhibition of platelet aggregation by polymorphonuclear leukocytes.

Thrombosis research 20030501

Neuroprotective actions of Selegiline in inhibiting 1-methyl, 4-phenyl, pyridinium ion (MPP+)-induced apoptosis in SK-N-SH neurons.

Journal of neurocytology 20030501

Carcinogenic semicarbazide induces sequence-specific DNA damage through the generation of reactive oxygen species and the derived organic radicals.

Mutation research 20030420

Latrunculin B or ATP depletion induces cofilin-dependent translocation of actin into nuclei of mast cells.

The Journal of biological chemistry 20030418

GTP-induced tetrodotoxin-resistant Na+ current regulates excitability in mouse and rat small diameter sensory neurones.

The Journal of physiology 20030415

GABA transmission in the nucleus accumbens is altered after withdrawal from repeated cocaine.

The Journal of neuroscience : the official journal of the Society for Neuroscience 20030415

2'(3')-O-(N-methylanthraniloyl)-substituted GTP analogs: a novel class of potent competitive adenylyl cyclase inhibitors.

The Journal of biological chemistry 20030411

Distinct regulation of expressed calcium channels 2.3 in Xenopus oocytes by direct or indirect activation of protein kinase C.

Brain research 20030411

Identification of a phosphothionate analogue of lysophosphatidic acid (LPA) as a selective agonist of the LPA3 receptor.

The Journal of biological chemistry 20030404

ATP modulation of sodium currents in rat dorsal root ganglion neurons.

Brain research 20030404

Monomeric complex of human orphan estrogen related receptor-2 with DNA: a pseudo-dimer interface mediates extended half-site recognition.

Journal of molecular biology 20030404

Effects of AICAR and exercise on insulin-stimulated glucose uptake, signaling, and GLUT-4 content in rat muscles.

Journal of applied physiology (Bethesda, Md. : 1985) 20030401

delta-Opioid receptors exhibit high efficiency when activating trimeric G proteins in membrane domains.

Journal of neurochemistry 20030401

Behavioural and gene transcription alterations induced by spontaneous cannabinoid withdrawal in mice.

Journal of neurochemistry 20030401

Sphingosine-1-phosphate and its potentially paradoxical effects on critical parameters of cutaneous wound healing.

The Journal of investigative dermatology 20030401

Differential regulation of GABA B receptor subunit expression and function.

The Journal of pharmacology and experimental therapeutics 20030401

Inhibition of human immunodeficiency virus 1 replication in vitro by a self-stabilized oligonucleotide with 2'-O-methyl-guanosine-uridine quadruplex motifs.

The Journal of antimicrobial chemotherapy 20030401

Dual effects of hexanol and halothane on the regulation of calcium sensitivity in airway smooth muscle.

Anesthesiology 20030401

Effects of D3.49A, R3.50A, and A6.34E mutations on ligand binding and activation of the cannabinoid-2 (CB2) receptor.

Biochemical pharmacology 20030401

Pharmacological characterisation of a cell line expressing GABA B1b and GABA B2 receptor subunits.

Biochemical pharmacology 20030401

Interaction of the D2short dopamine receptor with G proteins: analysis of receptor/G protein selectivity.

Biochemical pharmacology 20030401

DNA damage and repair system in spinal cord ischemia.

Journal of vascular surgery 20030401

Purification and characterization of 5'-methylthioadenosine phosphorylase from the hyperthermophilic archaeon Pyrococcus furiosus: substrate specificity and primary structure analysis.

Extremophiles : life under extreme conditions 20030401

Uncoupling of 5-HT1A receptors in the brain by estrogens: regional variations in antagonism by ICI 182,780.

Neuropharmacology 20030401

SKF83959 selectively regulates phosphatidylinositol-linked D1 dopamine receptors in rat brain.

Journal of neurochemistry 20030401

Arsenic-induced dysfunction in relaxation of blood vessels.

Environmental health perspectives 20030401

Covalent binding of leukotriene A4 to DNA and RNA.

Chemical research in toxicology 20030401

Control of rRNA expression in Escherichia coli.

Current opinion in microbiology 20030401

Mutations of F110 and C126 of the formyl peptide receptor interfere with G-protein coupling and chemotaxis.

Journal of periodontology 20030401

Exhaled NO and plasma cGMP increase after endotoxin infusion in healthy volunteers.

The European respiratory journal 20030401

The purine nucleoside cycle in cell-free extracts of rat brain: evidence for the occurrence of an inosine and a guanosine cycle with distinct metabolic roles.

Cellular and molecular life sciences : CMLS 20030401

A fully automated [35S]GTPgammaS scintillation proximity assay for the high-throughput screening of Gi-linked G protein-coupled receptors.

Assay and drug development technologies 20030401

The Orphan G protein-coupled receptors GPR41 and GPR43 are activated by propionate and other short chain carboxylic acids.

The Journal of biological chemistry 20030328

Active transducin alpha subunit carries PDE6 to detergent-resistant membranes in rod photoreceptor outer segments.

Biochemical and biophysical research communications 20030328

Molecular identification of nicotinic acid receptor.

Biochemical and biophysical research communications 20030328

Subject-regulated dosing alters morphine self-administration behavior and morphine-stimulated [35S]GTPgammaS binding.

Synapse (New York, N.Y.) 20030315

A G protein-coupled receptor responsive to bile acids.

The Journal of biological chemistry 20030314

Endogenous RGS protein action modulates mu-opioid signaling through Galphao. Effects on adenylyl cyclase, extracellular signal-regulated kinases, and intracellular calcium pathways.

The Journal of biological chemistry 20030314

GDP affinity and order state of the catalytic site are critical for function of xanthine nucleotide-selective Galphas proteins.

The Journal of biological chemistry 20030307

Design and synthesis of 3-phenyl tetrahydronaphthalenic derivatives as new selective MT2 melatoninergic ligands.

Bioorganic & medicinal chemistry 20030306

Unpredictable stereochemical preferences for mu opioid receptor activity in an exhaustively stereodiversified library of 1,4-enediols.

Organic letters 20030306

Restricting the conformational heterogeneity of RNA by specific incorporation of 8-bromoguanosine.

Journal of the American Chemical Society 20030305

Differential cholinergic activation of G proteins in rat and mouse brainstem: relevance for sleep and nociception.

The Journal of comparative neurology 20030303

Cardiac outflow of amino acids and purines during myocardial ischemia and reperfusion.

Journal of applied physiology (Bethesda, Md. : 1985) 20030301

The small GTPase RhoA has greater expression in small cell lung carcinoma than in non-small cell lung carcinoma and contributes to their unique morphologies.

International journal of oncology 20030301

Neuron-specific enolase, nucleotides, nucleosides, purine bases, oxypurines and uric acid concentrations in cerebrospinal fluid of children with meningitis.

Brain & development 20030301

Inhibition of cyclic guanosine 5'-monophosphate-dependent protein kinase I (PKG-I) in lumbar spinal cord reduces formalin-induced hyperalgesia and PKG upregulation.

Nitric oxide : biology and chemistry 20030301

Purine and deazapurine nucleosides: synthetic approaches, molecular modelling and biological activity.

Farmaco (Societa chimica italiana : 1989) 20030301

Adenosine A1 receptor-mediated presynaptic inhibition of GABAergic transmission in immature rat hippocampal CA1 neurons.

Journal of neurophysiology 20030301

Regulation of lymphocyte-mediated killing by GTP-binding proteins.

Journal of leukocyte biology 20030301

Functional coupling of the human dopamine D2 receptor with G alpha i1, G alpha i2, G alpha i3 and G alpha o G proteins: evidence for agonist regulation of G protein selectivity.

British journal of pharmacology 20030301

The effect of lead ions on the energy metabolism of human erythrocytes in vitro.

Comparative biochemistry and physiology. Toxicology & pharmacology : CBP 20030301

Complexes of cadmium ion with guanine bases detected by electrospray ionization mass spectrometry.

Journal of mass spectrometry : JMS 20030301

Effects of rolipram, pimobendan and zaprinast on ischaemia-induced dysrhythmias and on ventricular cyclic nucleotide content in the anaesthetized rat.

European journal of anaesthesiology 20030301

Positive allosteric modulation of the human metabotropic glutamate receptor 4 (hmGluR4) by SIB-1893 and MPEP.

British journal of pharmacology 20030301

h5-HT(1B) receptor-mediated constitutive Galphai3-protein activation in stably transfected Chinese hamster ovary cells: an antibody capture assay reveals protean efficacy of 5-HT.

British journal of pharmacology 20030301

Analysis of molecular determinants of affinity and relative efficacy of a series of R- and S-2-(dipropylamino)tetralins at the 5-HT1A serotonin receptor.

British journal of pharmacology 20030301

beta-MSH: a functional ligand that regulated energy homeostasis via hypothalamic MC4-R?

Peptides 20030301

Structural properties of the neutral and monoanionic forms of xanthosine, highly relevant to their substrate properties with various enzyme systems.

Nucleosides, nucleotides & nucleic acids 20030301

[Quantitation & optimization of guanosine fermentation process: prevention of NH4+ accumulation increases guanosine production by 70%].

Sheng wu gong cheng xue bao = Chinese journal of biotechnology 20030301

A spatial focusing model for G protein signals. Regulator of G protein signaling (RGS) protien-mediated kinetic scaffolding.

The Journal of biological chemistry 20030227

Effects of endogenous DNA base lesions on transcription elongation by mammalian RNA polymerase II. Implications for transcription-coupled DNA repair and transcriptional mutagenesis.

The Journal of biological chemistry 20030227

Activation of heterotrimeric G proteins by a high energy phosphate transfer via nucleoside diphosphate kinase (NDPK) B and Gbeta subunits. Complex formation of NDPK B with Gbeta gamma dimers and phosphorylation of His-266 IN Gbeta.

The Journal of biological chemistry 20030227

A comparison between the distinct inward currents activated in rat cultured dorsal root ganglion neurones by intracellular flash photolysis of two forms of caged cyclic guanosine monophosphate.

Neuroscience letters 20030227

Syntheses and opioid receptor binding affinities of 8-amino-2,6-methano-3-benzazocines.

Journal of medicinal chemistry 20030227

Tandem electrostatic effect from the first to the third aglycon in the trimeric RNA owing to the nearest-neighbor interaction.

Journal of the American Chemical Society 20030226

Factors that contribute to efficient catalytic activity of a small Ca2+-dependent deoxyribozyme in relation to its RNA cleavage function.

Biochemistry 20030225

Identification of a novel protein with guanylyl cyclase activity in Arabidopsis thaliana.

The Journal of biological chemistry 20030221

Searching for allosteric effects via QSAR. Part II.

Bioorganic & medicinal chemistry 20030220

Basal activity of GIRK5 isoforms.

Life sciences 20030214

Critical role of N-terminal N-glycosylation for proper folding of the human formyl peptide receptor.

Biochemical and biophysical research communications 20030214

Synthesis, opioid receptor binding, and functional activity of 5'-substituted 17-cyclopropylmethylpyrido[2',3':6,7]morphinans.

Bioorganic & medicinal chemistry letters 20030210

AF2 interaction with Ascaris suum body wall muscle membranes involves G-protein activation.

Biochemical and biophysical research communications 20030207

Mitochondrial biogenesis in mammals: the role of endogenous nitric oxide.

Science (New York, N.Y.) 20030207

Differential receptors create patterns diagnostic for ATP and GTP.

Journal of the American Chemical Society 20030205

The coenzyme thiamine pyrophosphate inhibits the self-splicing of the group I intron.

The international journal of biochemistry & cell biology 20030201

ATP-dependent interactions between Escherichia coli Min proteins and the phospholipid membrane in vitro.

Journal of bacteriology 20030201

The study of CXCR3 and CCR7 pharmacology using [35S]GTPgammaS exchange assays in cell membranes and permeabilized peripheral blood lymphocytes.

Journal of immunological methods 20030201

(2S,3R) beta-methyl-2',6'-dimethyltyrosine-L-tetrahydroisoquinoline-3-carboxylic acid [(2S,3R)TMT-L-Tic-OH] is a potent, selective delta-opioid receptor antagonist in mouse brain.

The Journal of pharmacology and experimental therapeutics 20030201

BAY41-2272, a novel nitric oxide independent soluble guanylate cyclase activator, relaxes human and rabbit corpus cavernosum in vitro.

The Journal of urology 20030201

Decreased modulation by lipopolysaccharide of aortic smooth muscle contractility in streptozotocin-induced hyperglycemic rats.

Journal of cardiovascular pharmacology 20030201

8'-aminoguanosine inclusion results in enhanced efflux of taurine in preconditioned ischemic myocardium.

Journal of cardiovascular pharmacology 20030201

In vitro distribution and characterization of membrane-associated PLD and PI-PLC in Brassica napus.

Journal of experimental botany 20030201

Synergism of nitric oxide and maturation signals on human dendritic cells occurs through a cyclic GMP-dependent pathway.

Journal of leukocyte biology 20030201

Principles: extending the utility of [35S]GTP gamma S binding assays.

Trends in pharmacological sciences 20030201

Simultaneous determination of purine nucleotides, their metabolites and beta-nicotinamide adenine dinucleotide in cerebellar granule cells by ion-pair high performance liquid chromatography.

Brain research. Brain research protocols 20030201

Dependence of the coupling of dopamine receptors to G proteins on the protein redox state in the neural plasma membranes of pond snail.

Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology 20030201

A unique phenotype of 5-HT2C, agonist-induced GTPgamma35S binding, transferable to 5-HT2A and 5-HT2B, upon swapping intracellular regions.

British journal of pharmacology 20030201

Nod factors activate both heterotrimeric and monomeric G-proteins in Vigna unguiculata (L.) Walp.

Planta 20030201

Molecular evidence for the functional role of dopamine D3 receptor in the morphine-induced rewarding effect and hyperlocomotion.

The Journal of neuroscience : the official journal of the Society for Neuroscience 20030201

G protein signaling in a neuronal network is necessary for rhythmic motor pattern production.

Journal of neurophysiology 20030201

Mycophenolic acid-induced apoptotic signal transduction in MOLT-4 T-cell.

Transplantation proceedings 20030201

UFP-101, a high affinity antagonist for the nociceptin/orphanin FQ receptor: radioligand and GTPgamma(35)S binding studies.

Naunyn-Schmiedeberg's archives of pharmacology 20030201

Antagonism of adenosine receptors by caffeine and caffeine metabolites in equine forebrain tissues.

American journal of veterinary research 20030201

Paracrine role of soluble guanylate cyclase and type III nitric oxide synthase in ovine fetal pulmonary circulation: a double labeling immunohistochemical study.

Histochemistry and cell biology 20030201

Inhibiting Ras signaling in the therapy of breast cancer.

Clinical breast cancer 20030201

Alkaline hydrolysis of cladribine.

Die Pharmazie 20030201

Biosynthesis of the 7-deazaguanosine hypermodified nucleosides of transfer RNA.

Bioorganic chemistry 20030201

Synthesis and biological activities of 2-functionalized purine nucleosides.

Nucleosides, nucleotides & nucleic acids 20030201

Guanine nucleotides guanosine 5'-diphosphate 3'-diphosphate and GTP co-operatively regulate the production of an antibiotic bacilysin in Bacillus subtilis.

The Journal of biological chemistry 20030124

ADP-ribosylation factor 4 small GTPase mediates epidermal growth factor receptor-dependent phospholipase D2 activation.

The Journal of biological chemistry 20030124

Interaction of human telomerase with its primer substrate.

Biochemistry 20030121

A ribozyme with michaelase activity: synthesis of the substrate precursors.

Bioorganic & medicinal chemistry 20030117

Effects of stress and tranylcypromine on amphetamine-induced locomotor activity and GABA(B) receptor function in rat brain.

Life sciences 20030117

Long-term interactions between opioid and cannabinoid agonists at the cellular level: cross-desensitization and downregulation.

Brain research 20030117

Alteration of 8-hydroxyguanosine concentrations in the cerebrospinal fluid and serum from patients with Parkinson's disease.

Neuroscience letters 20030116

Novel hexahydrospiro[piperidine-4,1'-pyrrolo[3,4-c]pyrroles]: highly selective small-molecule nociceptin/orphanin FQ receptor agonists.

Journal of medicinal chemistry 20030116

Endogenous phospholipase D2 localizes to the plasma membrane of RBL-2H3 mast cells and can be distinguished from ADP ribosylation factor-stimulated phospholipase D1 activity by its specific sensitivity to oleic acid.

The Biochemical journal 20030115

Down-regulation of deoxycytidine kinase in human leukemic cell lines resistant to cladribine and clofarabine and increased ribonucleotide reductase activity contributes to fludarabine resistance.

Biochemical pharmacology 20030115

Antiemetic and motor-depressive actions of CP55,940: cannabinoid CB1 receptor characterization, distribution, and G-protein activation.

European journal of pharmacology 20030110

Highly selective binding of organometallic ruthenium ethylenediamine complexes to nucleic acids: novel recognition mechanisms.

Journal of the American Chemical Society 20030108

Signal transduction of somatostatin in human B lymphoblasts.

American journal of physiology. Cell physiology 20030101

Cholesterol cell content modulates GTPase activity of G proteins in GH4C1 cell membranes.

Cellular signalling 20030101

P2Y(1) receptor activation inhibits NMDA receptor-channels in layer V pyramidal neurons of the rat prefrontal and parietal cortex.

Neurochemistry international 20030101

Ribavirin inhibits DNA, RNA, and protein synthesis in PHA-stimulated human peripheral blood mononuclear cells: possible explanation for therapeutic efficacy in patients with chronic HCV infection.

Journal of medical virology 20030101

The salivary purine nucleosidase of the mosquito, Aedes aegypti.

Insect biochemistry and molecular biology 20030101

Opioid receptor-induced GTPgamma35S binding during mouse development.

Developmental biology 20030101

Quinine inhibits vascular contraction independent of effects on calcium or myosin phosphorylation.

The Journal of pharmacology and experimental therapeutics 20030101

Constitutive coupling of a chimeric dopamine D2/alpha 1B receptor to the phospholipase C pathway: inverse agonism to silent antagonism by neuroleptic drugs.

The Journal of pharmacology and experimental therapeutics 20030101

Crystallization and preliminary X-ray crystallographic analysis of tRNA(m1G37)methyltransferase from Haemophilus influenzae.

Acta crystallographica. Section D, Biological crystallography 20030101

P53 mediates the apoptotic response to GTP depletion after renal ischemia-reperfusion: protective role of a p53 inhibitor.

Journal of the American Society of Nephrology : JASN 20030101

Metabotropic glutamate receptors promote neuronal and vascular plasticity through novel intracellular pathways.

Histology and histopathology 20030101

Determination of total potentially available nucleosides in human milk from Asian women.

Nutrition (Burbank, Los Angeles County, Calif.) 20030101

Activity of opioid ligands in cells expressing cloned mu opioid receptors.

BMC pharmacology 20030101

Acetylcholine-induced vasodilation may depend entirely upon NO in the femoral artery of young piglets.

British journal of pharmacology 20030101

Clustering of nucleosides in the presence of alkali metals: Biologically relevant quartets of guanosine, deoxyguanosine and uridine observed by ESI-MS/MS.

Journal of mass spectrometry : JMS 20030101

Nitric oxide decreases the production of inositol phosphates stimulated by angiotensin II and thyrotropin-releasing hormone in anterior pituitary cells.

European journal of endocrinology 20030101

A novel assay system implicates PtdIns(3,4)P(2), PtdIns(3)P, and PKC delta in intracellular production of reactive oxygen species by the NADPH oxidase.

Molecular cell 20030101

Suppression of the morphine-induced rewarding effect and G-protein activation in the lower midbrain following nerve injury in the mouse: involvement of G-protein-coupled receptor kinase 2.

Neuroscience 20030101

Mycophenolic acid inhibits inosine 5'-monophosphate dehydrogenase and suppresses immunoglobulin and cytokine production of B cells.

International immunopharmacology 20030101

Functional interaction of CFTR and ENaC in sweat glands.

Pflugers Archiv : European journal of physiology 20030101

Chronic fluoxetine induces opposite changes in G protein coupling at pre and postsynaptic 5-HT1A receptors in rat brain.

Neuropharmacology 20030101

Maturation alters cyclic nucleotide and relaxation responses to nitric oxide donors in ovine cerebral arteries.

Biology of the neonate 20030101

The bradykinin BK2 receptor mediates angiotensin II receptor type 2 stimulated rat duodenal mucosal alkaline secretion.

BMC physiology 20030101

Functional characterisation of the putative somatostatin sst2 receptor antagonist CYN 154806.

Naunyn-Schmiedeberg's archives of pharmacology 20030101

Role of the M2 muscarinic receptor pathway in lidocaine-induced potentiation of the relaxant response to atrial natriuretic peptide in bovine tracheal smooth muscle.

Naunyn-Schmiedeberg's archives of pharmacology 20030101

Roles of cyclic GMP in modulating ovarian functions.

Reproductive biomedicine online 20030101

Relationship between the nonlinear ferroelectric and liquid crystal models for microtubules.

Physical review. E, Statistical, nonlinear, and soft matter physics 20030101

Mu opioid receptor signaling in morphine sensitization.

Neuroscience 20030101

The angiotensin II receptor type 2 agonist CGP 42112A stimulates NO production in the porcine jejunal mucosa.

BMC pharmacology 20030101

Signaling through NO and cGMP-dependent protein kinases.

Annals of medicine 20030101

Evidence for disaggregation of oligomeric G(o)alpha induced by guanosine-5;-3-O-(thio)triphosphate activation.

Biochemistry. Biokhimiia 20030101

Structure-activity relationships of dynorphin analogs substituted in positions 2 and 3.

Biopolymers 20030101

Genetic instability of (GATA)n microsatellite DNA repeats and somatic mosaicism in the unisexual lizards Darevskia unisexualis.

Doklady. Biochemistry and biophysics 20030101

Covalent binding of leukotriene A4 to nucleosides, nucleotides, and nucleic acids.

Advances in experimental medicine and biology 20030101

Chemical modifications of alpha1,6-fucosyltransferase define amino acid residues of catalytic importance.

Biochimie 20030101

Inflammatory breast cancer: relationship between growth factor signaling and motility in aggressive cancers.

Breast cancer research : BCR 20030101

Activation of A(3) receptors by endogenous adenosine inhibits synaptic transmission during hypoxia in rat cortical neurons.

Restorative neurology and neuroscience 20030101

Wegener's granulomatosis: current and upcoming therapies.

Arthritis research & therapy 20030101

Evidence of increased dopamine receptor signaling in food-restricted rats.

Neuroscience 20030101

Drosophila S3 ribosomal protein accelerates repair of 8-oxoguanine performed by human and mouse cell extracts.

Environmental and molecular mutagenesis 20030101

Nitric oxide synthase activity in human trophoblast, term placenta and pregnant myometrium.

Reproductive biology and endocrinology : RB&E 20030101

Changes in hippocampal histamine receptors across the hibernation cycle in ground squirrels.

Hippocampus 20030101

Valacyclovir in the treatment of herpes simplex, herpes zoster, and other viral infections.

Journal of cutaneous medicine and surgery 20030101

Increased brain histamine H3 receptor expression during hibernation in golden-mantled ground squirrels.

BMC neuroscience 20030101

Design, synthesis and analysis of antiviral nucleosides bearing pyrrolepolyamide binding to nucleic acid (II): N2-pyrrolepolyamidopropylguanosine.

Nucleic acids research. Supplement (2001) 20030101

Conformationally constrained tricyclic nucleosides. Role of electronic and steric factors.

Nucleic acids research. Supplement (2001) 20030101

Properties of Arg389-beta1-adrenoceptor-Gsalpha fusion proteins: comparison with Gly389-beta1-adrenoceptor-Gsalpha fusion proteins.

Receptors & channels 20030101

G-protein modulators alter the swimming behavior and calcium influx of Paramecium tetraurelia.

The Journal of eukaryotic microbiology 20030101

MDPSCL2: a new protecting group for chemoselective synthesis of 2'-O-alkylated guanosines.