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117-89-5 | 10H-Phenothiazine, 10-[3-(4-methyl-1-piperazinyl)propyl]-2-(trifluoromethyl)-
CAS No: 117-89-5 Catalog No: AG000DJ9 MDL No:MFCD00242601
Product Description
Catalog Number:
AG000DJ9
Chemical Name:
10H-Phenothiazine, 10-[3-(4-methyl-1-piperazinyl)propyl]-2-(trifluoromethyl)-
CAS Number:
117-89-5
Molecular Formula:
C21H24F3N3S
Molecular Weight:
407.4956
MDL Number:
MFCD00242601
IUPAC Name:
10-[3-(4-methylpiperazin-1-yl)propyl]-2-(trifluoromethyl)phenothiazine
InChI:
InChI=1S/C21H24F3N3S/c1-25-11-13-26(14-12-25)9-4-10-27-17-5-2-3-6-19(17)28-20-8-7-16(15-18(20)27)21(22,23)24/h2-3,5-8,15H,4,9-14H2,1H3
InChI Key:
ZEWQUBUPAILYHI-UHFFFAOYSA-N
SMILES:
CN1CCN(CC1)CCCN1c2ccccc2Sc2c1cc(cc2)C(F)(F)F
EC Number:
204-219-4
UNII:
214IZI85K3
Properties
Complexity:
510
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
1
Defined Atom Stereocenter Count:
0
Defined Bond Stereocenter Count:
0
Exact Mass:
407.164g/mol
Formal Charge:
0
Heavy Atom Count:
28
Hydrogen Bond Acceptor Count:
7
Hydrogen Bond Donor Count:
0
Isotope Atom Count:
0
Molecular Weight:
407.499g/mol
Monoisotopic Mass:
407.164g/mol
Rotatable Bond Count:
4
Topological Polar Surface Area:
35A^2
Undefined Atom Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
XLogP3:
5
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| Ca2+ dependence and inhibitory effects of trifluoperazine on plasma membrane ATPase of Thermoactinomyces vulgaris. | Current microbiology 20040701 |
| Quaternary ammonium-linked glucuronidation of tamoxifen by human liver microsomes and UDP-glucuronosyltransferase 1A4. | Biochemical pharmacology 20040601 |
| Role for malonyl coenzyme A:acyl carrier protein transacylase (MCAT) in the growth-inhibitory effect of the calmodulin antagonist trifluoperazine in Mycobacterium bovis BCG. | The Journal of antimicrobial chemotherapy 20040601 |
| Alendronic acid for antipsychotic-related osteopenia. | The American journal of psychiatry 20040401 |
| Interaction of two phenothiazine derivatives with phospholipid monolayers. | Biophysical chemistry 20040401 |
| Developmental-stage-specific triacylglycerol biosynthesis, degradation and trafficking as lipid bodies in Plasmodium falciparum-infected erythrocytes. | Journal of cell science 20040315 |
| Mechanism of protective effect of energostim during catalepsy produced by single treatment with trifluoperazine. | Bulletin of experimental biology and medicine 20040301 |
| Anticataleptic effect of energostim during single treatment with trifluoperazine. | Bulletin of experimental biology and medicine 20040301 |
| Calmodulin inhibitor trifluoperazine attenuates the development and expression of morphine-induced conditioned place preference in rats. | European journal of pharmacology 20040223 |
| Anti-inflammatory flavonoids and pterocarpanoid from Crotalaria pallida and C. assamica. | Bioorganic & medicinal chemistry letters 20040223 |
| Suppressive effect of regucalcin on protein phosphatase activity in the heart cytosol of normal and regucalcin transgenic rats. | International journal of molecular medicine 20040201 |
| Identification of human UDP-glucuronosyltransferase enzyme(s) responsible for the glucuronidation of posaconazole (Noxafil). | Drug metabolism and disposition: the biological fate of chemicals 20040201 |
| Discovering modes of action for therapeutic compounds using a genome-wide screen of yeast heterozygotes. | Cell 20040109 |
| New agents active against Mycobacterium avium complex selected by molecular topology: a virtual screening method. | The Journal of antimicrobial chemotherapy 20040101 |
| NMDA receptor-mediated immediate Ser831 phosphorylation of GluR1 through CaMKIIalpha in rat hippocampus during early global ischemia. | Neuroscience research 20040101 |
| Calcium is involved in photomovement of cyanobacterium Synechocystis sp. PCC 6803. | Photochemistry and photobiology 20040101 |
| Oxidative stress underlies the mechanism for Ca(2+)-induced permeability transition of mitochondria. | Free radical research 20040101 |
| Unusual Ca(2+)-calmodulin binding interactions of the microtubule-associated protein F-STOP. | Biochemistry 20031007 |
| The role of calmodulin in the regulation of osteoclastogenesis. | Endocrinology 20031001 |
| Calcium activates SK channels in the intact human lens. | Investigative ophthalmology & visual science 20030901 |
| Enhancement of plasmid curing by 9-aminoacridine and two phenothiazines in the presence of proton pump inhibitor 1-(2-benzoxazolyl)-3,3,3-trifluoro-2-propanone. | International journal of antimicrobial agents 20030901 |
| Cold-induced apoptosis of rat liver endothelial cells: contribution of mitochondrial alterations. | Transplantation 20030815 |
| Regulatory effect of regucalcin on nitric oxide synthase activity in rat kidney cortex cytosol: Role of endogenous regucalcin in transgenic rats. | International journal of molecular medicine 20030801 |
| Functional and genetic characterization of calmodulin from the dimorphic and pathogenic fungus Paracoccidioides brasiliensis. | Fungal genetics and biology : FG & B 20030801 |
| Activities of therapeutic agents against Naegleria fowleri in vitro and in a mouse model of primary amebic meningoencephalitis. | The Journal of parasitology 20030801 |
| Mitotracker green is a P-glycoprotein substrate. | Bioscience reports 20030801 |
| Gliotoxin-mediated apoptosis of activated human hepatic stellate cells. | Journal of hepatology 20030701 |
| Suppressive effect of endogenous regucalcin on nitric oxide synthase activity in cloned rat hepatoma H4-II-E cells overexpressing regucalcin. | Journal of cellular biochemistry 20030701 |
| [Construction and expression of anti-CD3/ anti-Pgp Diabody]. | Sheng wu gong cheng xue bao = Chinese journal of biotechnology 20030701 |
| Cytotoxic mechanisms of hydrosulfide anion and cyanide anion in primary rat hepatocyte cultures. | Toxicology 20030630 |
| Evaluation of a synergistic combination between the non-antibiotic microbicides diclofenac and trifluoperazine. | International journal of antimicrobial agents 20030601 |
| Inhibitory role of regucalcin in the regulation of nitric oxide synthase activity in rat brain cytosol: involvement of aging. | Journal of the neurological sciences 20030515 |
| Trifluoperazine effects on anionic and zwitterionic micelles: a study by small angle X-ray scattering. | Journal of colloid and interface science 20030415 |
| Calmodulin antagonists suppress gap junction coupling in isolated Hensen cells of the guinea pig cochlea. | Pflugers Archiv : European journal of physiology 20030401 |
| 3-[2-[4-(3-chloro-2-methylphenyl)-1-piperazinyl]ethyl]-5,6-dimethoxy-1-(4-imidazolylmethyl)-1H-indazole dihydrochloride 3.5 hydrate (DY-9760e), a novel calmodulin antagonist, reduces brain edema through the inhibition of enhanced blood-brain barrier permeability after transient focal ischemia. | The Journal of pharmacology and experimental therapeutics 20030301 |
| H1-histamine receptor affinity predicts short-term weight gain for typical and atypical antipsychotic drugs. | Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20030301 |
| Anti-inflammatory constituents and new pterocarpanoid of Crotalaria pallida. | Journal of natural products 20030301 |
| Chlorophyll antenna size adjustments by irradiance in Dunaliella salina involve coordinate regulation of chlorophyll a oxygenase (CAO) and Lhcb gene expression. | Plant molecular biology 20030301 |
| The voltage- and time-dependent blocking effect of trifluoperazine on T lymphocyte Kv1.3 channels. | Biochemical pharmacology 20030215 |
| Calmodulin and calmodulin-dependent kinase II mediate neuronal cell death induced by depolarization. | Brain research 20030207 |
| Calcium-induced mitochondrial swelling and cytochrome c release in the brain: its biochemical characteristics and implication in ischemic neuronal injury. | Brain research 20030117 |
| Trans-Golgi network and subapical compartment of HepG2 cells display different properties in sorting and exiting of sphingolipids. | The Journal of biological chemistry 20030103 |
| Characterization of PMCA isoforms and their contribution to transcellular Ca2+ flux in MDCK cells. | American journal of physiology. Renal physiology 20030101 |
| Regulation of glutamatergic neurotransmission in the striatum by presynaptic adenylyl cyclase-dependent processes. | Neurochemistry international 20030101 |
| Acute dystonia caused by low dosage of olanzapine. | The Journal of neuropsychiatry and clinical neurosciences 20030101 |
| Integrins regulate neuronal neurotrophin gene expression through effects on voltage-sensitive calcium channels. | Neuroscience 20030101 |
| Gravitactic signal transduction elements in Astasia longa investigated during parabolic flights. | Microgravity science and technology 20030101 |
| Pharmacophore model of drugs involved in P-glycoprotein multidrug resistance: explanation of structural variety (hypothesis). | Journal of medicinal chemistry 20021219 |
| Effects of immunosuppressants, calcineurin inhibition, and blockade of endoplasmic reticulum calcium channels on free fatty acid efflux from the ischemic/reperfused rat cerebral cortex. | Brain research 20021206 |
| Calmodulin modulates the delay period between release of calcium from internal stores and activation of calcium influx via endogenous TRP1 channels. | The Journal of biological chemistry 20021101 |
| Mirtazapine use in two pregnant women: is it safe? | Teratology 20021101 |
| Synthesis and antiinflammatory evaluation of 9-anilinoacridine and 9-phenoxyacridine derivatives. | Journal of medicinal chemistry 20021010 |
| Novel protein kinase induced during sporangial cleavage in the oomycete Phytophthora infestans. | Eukaryotic cell 20021001 |
| Possible role of calcium ions, calcium channels and calmodulin in excystation and metacystic development of Entamoeba invadens. | Parasitology research 20020901 |
| Nucleotide triphosphatase/helicase of hepatitis C virus as a target for antiviral therapy. | Antiviral research 20020901 |
| Physiological concentrations of melatonin inhibit the nitridergic pathway in the Syrian hamster retina. | Journal of pineal research 20020801 |
| Biosynthesis of triacylglycerol molecular species in an oleaginous fungus, Mortierella ramanniana var. angulispora. | Journal of biochemistry 20020701 |
| Successful treatment of a complicated case of neuroleptic malignant syndrome. | Intensive care medicine 20020701 |
| A 40-year-old woman who noticed a medication error, 1 year later. | JAMA 20020626 |
| Real-time monitoring of P-glycoprotein activation in living cells. | Biochemistry 20020625 |
| Imipramine N-glucuronidation in human liver microsomes: biphasic kinetics and characterization of UDP-glucuronosyltransferase isoforms. | Drug metabolism and disposition: the biological fate of chemicals 20020601 |
| Signal transduction controlling the blue- and red-light mediated gene expression of S-adenosylmethionine decarboxylase in Pharbitis nil. | Journal of experimental botany 20020601 |
| Regulation of apical transporter of L-DOPA in human intestinal Caco-2 cells. | Acta physiologica Scandinavica 20020601 |
| LVV-hemorphin-4 modulates Ca2+/calmodulin-dependent pathways in the immune system by the same mechanism as in the brain. | Journal of molecular neuroscience : MN 20020601 |
| Stimulation of trehalose efflux from cockroach (Periplaneta americana) fat body by hypertrehalosemic hormone is dependent on protein kinase C and calmodulin. | Archives of insect biochemistry and physiology 20020501 |
| Thioridazine interacts with the membrane of mitochondria acquiring antioxidant activity toward apoptosis--potentially implicated mechanisms. | British journal of pharmacology 20020501 |
| Sustained ER Ca2+ depletion suppresses protein synthesis and induces activation-enhanced cell death in mast cells. | The Journal of biological chemistry 20020419 |
| Effect of calmodulin antagonists on phospholipase D activity in SH-SY5Y cells. | Neurochemistry international 20020301 |
| Colour reactions of PH. EUR. for identification of drugs using 1,3-dibromo-5,5-dimethylhydantoin (DBH) instead of elemental bromine. Analytical methods of pharmacopoeias with DBH in respect to environmental and economical concern, Part 10. | Die Pharmazie 20020301 |
| Effects of trifluoperazine on the contraction kinetics of the isolated intact tracheal and pulmonary artery smooth muscle. | The Thoracic and cardiovascular surgeon 20020201 |
| Atypical antipsychotics: mechanism of action. | Canadian journal of psychiatry. Revue canadienne de psychiatrie 20020201 |
| Calcium involvement in the luminescence control of three ophiuroid species (Echinodermata). | Comparative biochemistry and physiology. Toxicology & pharmacology : CBP 20020201 |
| Structure-based computational database screening, in vitro assay, and NMR assessment of compounds that target TAR RNA. | Chemistry & biology 20020201 |
| Involvement of calmodulin inhibition in analgesia induced with low doses of intrathecal trifluoperazine. | Japanese journal of pharmacology 20020201 |
| Derivative spectrophotometric, thin layer chromatographic-densitometric and high performance liquid chromatographic determination of trifluoperazine hydrochloride in presence of its hydrogen peroxide induced-degradation product. | Journal of pharmaceutical and biomedical analysis 20020101 |
| Shattered trust: technical and moral lessons from an interrupted first visit. | Harvard review of psychiatry 20020101 |
| Cellular mechanism underlying LPS-induced inhibition of in vitro L-leucine transport across rabbit jejunum. | Journal of endotoxin research 20020101 |
| Spectrophotometric determination of the phosphatidylcholine liposomes/water partition coefficients and the protonation equilibrium constants of phenothiazine derivatives. | Cellular & molecular biology letters 20020101 |
| NTPase/helicase of Flaviviridae: inhibitors and inhibition of the enzyme. | Acta biochimica Polonica 20020101 |
| Signal transduction in lemon seedlings in the hypersensitive response against Alternaria alternata: participation of calmodulin, G-protein and protein kinases. | Biological research 20020101 |
| Effect of serum and hydrogen peroxide on the Ca2+/calmodulin-dependent phosphorylation of eukaryotic elongation factor 2(eEF-2) in Chinese hamster ovary cells. | Experimental & molecular medicine 20011231 |
| Induction of apoptosis by Phenothiazine derivatives in V79 cells. | Toxicology letters 20011215 |
| Photodynamic therapy-induced apoptosis in epidermoid carcinoma cells. Reactive oxygen species and mitochondrial inner membrane permeabilization. | The Journal of biological chemistry 20011214 |
| Effects of calcium, calmodulin, protein kinase C and protein tyrosine kinases on volume-activated taurine efflux in human erythroleukemia cells. | Journal of cellular physiology 20011201 |
| Bifonazole modulates death of cultured cerebellar granular cells induced by glutamate and oxygen-glucose deprivation. | Bulletin of experimental biology and medicine 20011101 |
| Calmodulin inhibitors trigger the proteolytic processing of membrane type-1 matrix metalloproteinase, but not its shedding in glioblastoma cells. | The Biochemical journal 20011015 |
| Participation of Ca2+/calmodulin during activation of rat neutrophils by polychlorinated biphenyls. | Biochemical pharmacology 20011015 |
| Laryngeal dystonia secondary to neuroleptic medications. | The Medical journal of Australia 20011015 |
| L-selectin shedding is independent of its subsurface structures and topographic distribution. | Journal of immunology (Baltimore, Md. : 1950) 20011001 |
| Spectrophotometric determination of trifluoperazine HCl and isopropamide iodide in binary mixture using second derivative and second derivative of the ratio spectra methods. | Journal of pharmaceutical and biomedical analysis 20010901 |
| P glycoprotein-mediated cholesterol cycling determines proximal tubular cell viability. | Kidney international 20010901 |
| Benzyloxybenzaldehyde analogues as novel adenylyl cyclase activators. | Bioorganic & medicinal chemistry letters 20010806 |
| Calmodulin antagonists inhibit T-type Ca(2+) currents in mouse spermatogenic cells and the zona pellucida-induced sperm acrosome reaction. | Developmental biology 20010801 |
| Detection of calmodulin-binding proteins and calmodulin-dependent phosphorylation linked to calmodulin-dependent chemotaxis to folic and cAMP in Dictyostelium. | Cellular signalling 20010801 |
| Suppressive effect of endogenous regucalcin on guanosine triphosphatase activity in rat liver nucleus. | Biological & pharmaceutical bulletin 20010801 |
| Effect of bilirubin on toxicity induced by trifluoperazine, dibucaine and praziquantel to erythrocytes. | Life sciences 20010713 |
| Antisecretory effect of loperamide in colon epithelial cells by inhibition of basolateral K+ conductance. | Scandinavian journal of gastroenterology 20010701 |
| Inhibitory effect of regucalcin on protein phosphatase activity in the nuclei of rat kidney cortex. | Journal of cellular biochemistry 20010601 |
| [High-level expression of human calmodulin in E. coli and its effects on cell proliferation]. | Shi yan sheng wu xue bao 20010601 |
| Cell cycle effects of the phenothiazines: trifluoperazine and chlorpromazine in Candida albicans. | FEMS microbiology letters 20010530 |
| Calmodulin enhances the stability of the estrogen receptor. | The Journal of biological chemistry 20010518 |
| DNA-dependent protein kinase is inhibited by trifluoperazine. | Biochemical and biophysical research communications 20010518 |
| Inhibition of T-cell invasion across cultured fibroblast monolayers by phenothiazine-related calmodulin inhibitors: impairment of lymphocyte motility by trifluoperazine and chlorpromazine, and alteration of the monolayer by pimozide. | Biochemical pharmacology 20010515 |
| Activity of phenothiazines against antibiotic-resistant Mycobacterium tuberculosis: a review supporting further studies that may elucidate the potential use of thioridazine as anti-tuberculosis therapy. | The Journal of antimicrobial chemotherapy 20010501 |
| Inhibition of choline acetyltransferase by excitatory amino acids as a possible mechanism for cholinergic dysfunction in the central nervous system. | Journal of neurochemistry 20010501 |
| Prolactin directly stimulates transcellular active calcium transport in the duodenum of female rats. | Canadian journal of physiology and pharmacology 20010501 |
| Selective dopaminergic vulnerability: 3,4-dihydroxyphenylacetaldehyde targets mitochondria. | Free radical biology & medicine 20010415 |
| Induction of early growth response-1 gene expression by calmodulin antagonist trifluoperazine through the activation of Elk-1 in human fibrosarcoma HT1080 cells. | The Journal of biological chemistry 20010316 |
| Nephron distribution of total low Km cyclic AMP phosphodiesterase in mouse, rat and rabbit kidney. | The Tohoku journal of experimental medicine 20010301 |
| Trifluoperazine induces domain formation in zwitterionic phosphatidylcholine but not in charged phosphatidylglycerol bilayers. | Biochimica et biophysica acta 20010209 |
| Voltage dependence of the [Ca2+](i) oscillations system, in the Mg2+ -stimulated oocyte of the prawn Palaemon serratus. | Cell calcium 20010201 |
| Role of calcium and calmodulin in ciliary stimulation induced by acetylcholine. | American journal of physiology. Cell physiology 20010101 |
| Use of trifluoroperazine isolates a [(3)H]Ifenprodil binding site in rat brain membranes with the pharmacology of the voltage-independent ifenprodil site on N-methyl-D-aspartate receptors containing NR2B subunits. | The Journal of pharmacology and experimental therapeutics 20010101 |
| Superoxide radical-initiated apoptotic signalling pathway in selenite-treated HepG(2) cells: mitochondria serve as the main target. | Free radical biology & medicine 20010101 |
| Inhibition of the type 1 inositol 1,4,5-trisphosphate-sensitive Ca2+ channel by calmodulin antagonists. | Cellular signalling 20010101 |
| Inhibition of calcium-independent luminal uptake of L-dopa by calmodulin antagonists in immortalized rat capillary cerebral endothelial cells. | Cell biology international 20010101 |
| Regulatory role of endogenous regucalcin in the enhancement of nuclear deoxyribonuleic acid synthesis with proliferation of cloned rat hepatoma cells (H4-II-E). | Journal of cellular biochemistry 20010101 |
| Alterations in the protein pattern of subcellular fractions isolated from Paramecium cells suppressed in phagocytosis. | Folia histochemica et cytobiologica 20010101 |
| NADPH-induced oxidative damage of rat liver microsomes: protective role of chlorpromazine and trifluoperazine. | Polish journal of pharmacology 20010101 |
| Differential cellular regulation of the mitochondrial permeability transition in an in vitro model of 1,3-dinitrobenzene-induced encephalopathy. | Brain research 20000825 |
| Block of rat brain recombinant SK channels by tricyclic antidepressants and related compounds. | European journal of pharmacology 20000728 |
| A new potent calmodulin antagonist with arylalkylamine structure: crystallographic, spectroscopic and functional studies. | Journal of molecular biology 20000331 |
| Neuroleptic malignant syndrome after venlafaxine. | Lancet (London, England) 20000122 |
| Biochemical properties of a minimal functional domain with ATP-binding activity of the NTPase/helicase of hepatitis C virus. | European journal of biochemistry 19991201 |
| In vitro susceptibility testing of Mycobacterium tuberculosis strains to trifluoperazine. | Journal of chemotherapy (Florence, Italy) 19990601 |
| Tardive blepharospasm. | Movement disorders : official journal of the Movement Disorder Society 19981101 |
| Fits and starts. | Postgraduate medical journal 19981101 |
| Effect of trifluoperazine, a potential drug for tuberculosis with psychotic disorders, on the growth of clinical isolates of drug resistant Mycobacterium tuberculosis. | International clinical psychopharmacology 19980501 |
| Bioluminescence assay of adenosine triphosphate in drug susceptibility testing of Mycobacterium tuberculosis. | The Indian journal of medical research 19980201 |
| Calcium- and calmodulin-dependent PMA-activation of the CD44 adhesion molecule. | Cell adhesion and communication 19980101 |
| Bilateral ulnar nerve paralysis: an unreported complication of drug-induced extrapyramidal rigidity. | The Australian and New Zealand journal of psychiatry 19970601 |
| Dysarthria: lonely symptom of tardive dystonia. | Canadian journal of psychiatry. Revue canadienne de psychiatrie 19970501 |
| Effect of aspartate and glutamate on nociception, catalepsy and core temperature in rats. | Indian journal of physiology and pharmacology 19970401 |
| Atypical neuroleptics have low affinity for dopamine D2 receptors or are selective for D4 receptors. | Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 19970201 |
| Drug-induced Parkinsonism associated with dysphagia and aspiration: a brief report. | Journal of geriatric psychiatry and neurology 19960701 |
| In-vitro and intracellular antimycobacterial activity of trifluoperazine. | The Journal of antimicrobial chemotherapy 19960101 |
| Exacerbation of extrapyramidal symptoms with paroxetine. | The Australian and New Zealand journal of psychiatry 19950901 |
| Effects of concomitant risperidone and lithium treatment. | The American journal of psychiatry 19950701 |
| Evidence for a functional interaction between calmodulin and the glucocorticoid receptor. | Biochemical and biophysical research communications 19950308 |
| In vitro effects of artemisinin ether, cycloguanil hydrochloride (alone and in combination with sulfadiazine), quinine sulfate, mefloquine, primaquine phosphate, trifluoperazine hydrochloride, and verapamil on Toxoplasma gondii. | Antimicrobial agents and chemotherapy 19940601 |
| Enhancement of metallothionein gene expression in male Wistar (WF/NCr) rats by treatment with calmodulin inhibitors: potential role of calcium regulatory pathways in metallothionein induction. | Toxicology and applied pharmacology 19940301 |
| Dopamine D4 versus D2 receptor selectivity of dopamine receptor antagonists: possible therapeutic implications. | European journal of pharmacology 19930604 |
| Effect of chronic trifluoperazine administration and subsequent withdrawal on the production and persistence of perioral behaviours in two rat strains. | Psychopharmacology 19930101 |
| Extra pyramidal side effects associated with paroxetine. | West of England medical journal 19921201 |
| Neuroleptic-induced catatonia as a stage in the progression toward neuroleptic malignant syndrome. | Journal of the American Academy of Child and Adolescent Psychiatry 19921101 |
| Antitubercular activity of trifluoperazine, a calmodulin antagonist. | FEMS microbiology letters 19921001 |
| Pisa syndrome in an adolescent on neuroleptic medication. | The British journal of psychiatry : the journal of mental science 19910301 |
| Organic amnestic disorder: a long-term sequel after neuroleptic malignant syndrome. | Biological psychiatry 19910215 |
| On the selection of mice for haloperidol response and non-response. | Psychopharmacology 19910101 |
| Pseudo-tetanus following trifluoperazine. | The Ulster medical journal 19901001 |
| Phentermine and psychosis. | The British journal of psychiatry : the journal of mental science 19900301 |
| Association of high prolactin levels and neuroleptics immediately postpartum. | The Journal of neuropsychiatry and clinical neurosciences 19900101 |
| The effects of chronic treatment and withdrawal of CNS depressants on aggressive behavior. | Toxicology and industrial health 19891201 |
| [Prevention of adrenaline-induced arrhythmia by a calmodulin blocker, trifluoroperazine]. | Biulleten' eksperimental'noi biologii i meditsiny 19890701 |
| Blinking-blepharospasm after long-term neuroleptic treatment. | The Medical journal of Australia 19890320 |
| Cosecretion of calcitonin and calcitonin gene-related peptide from cultured rat medullary thyroid C cells. | Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 19890201 |
| Bromocriptine sensitization of neuroleptic-induced acute dystonia. | Journal of clinical psychopharmacology 19881001 |
| Characterization of the ATPase activity of the Mr 170,000 to 180,000 membrane glycoprotein (P-glycoprotein) associated with multidrug resistance in K562/ADM cells. | Cancer research 19880901 |
| Comparative short-term evaluation of penfluridol and trifluoperazine in chronic schizophrenia. | Indian journal of physiology and pharmacology 19880101 |
| Potentiation of small cell lung cancer-related SIADH by trifluoperazine. | European journal of respiratory diseases 19871101 |
| [Influence of trifluoperazine and flunarizine on the late myocardial toxicity of doxorubicin]. | Cardiologia (Rome, Italy) 19870901 |
| Cytogenetic effects of trifluoperazine in mice. | Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 19870801 |
| Combination of trazodone and phenothiazines: a possible additive hypotensive effect. | Canadian journal of psychiatry. Revue canadienne de psychiatrie 19861201 |
| Susceptibility to drug-induced hypotension in post-partum psychosis. | International clinical psychopharmacology 19860101 |
| Drug-induced torsade de pointes. | Clinical pharmacy 19850101 |
| Sigma opiates and certain antipsychotic drugs mutually inhibit (+)-[3H] SKF 10,047 and [3H]haloperidol binding in guinea pig brain membranes. | Proceedings of the National Academy of Sciences of the United States of America 19840901 |
| Intravenous lorazepam in neuroleptic-induced catatonia. | Journal of clinical psychopharmacology 19831201 |
| An unusual schizophrenic illness responsive to pyridoxine HCl (B6) subsequent to phenothiazine and butyrophenone toxicities. | Biological psychiatry 19831101 |
| Development of radioimmunoassays for trifluoperazine and their application to metabolic studies of the drug. | Journal of pharmacological methods 19830601 |
| Rate of blinking may predict neuroleptic-induced parkinsonism. | The British journal of psychiatry : the journal of mental science 19830401 |
| Sexual dysfunction in women using major tranquilizers. | Psychosomatics 19820901 |
| Drug-induced rapid cycling: possible outcomes and management. | The American journal of psychiatry 19820701 |
| Stuttering: an unusual side effect of phenothiazines. | The American journal of psychiatry 19810301 |
| The syndrome of inappropriate secretion of antidiuretic hormone associated with amitriptyline or trifluoperazine administration. | The Journal of the Kansas Medical Society 19801001 |
| Benztropine prophylaxis of dystonic reactions. | Psychopharmacology 19790328 |
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| First-degree atrioventricular block during lithium carbonate treatment. | The American journal of psychiatry 19770101 |
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| Anticholinergic exacerbation of phenothiazine-induced extrapyramidal syndrome. | The American journal of psychiatry 19760901 |
| Low urinary dopamine and prediction of phenothiazine-induced Parkinsonism: a preliminary report. | The American journal of psychiatry 19760601 |
| High-dosage and versatile drug therapy with treatment-resistant psychotic patients. | Hospital & community psychiatry 19760101 |
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| Implications of phenothiazine side effects: a study of antiparkinsonian agents in an older population. | Acta psychiatrica Scandinavica 19750201 |
| Treatment of phenothiazine induced bulbar persistent dyskinesia with deanol acetamidobenzoate. | Diseases of the nervous system 19750201 |
| Tissue metabolites of trifluorperazine, fluphenazine, prochlorperazine, and perphenazine. Kinetics in chronic treatment. | Drug metabolism and disposition: the biological fate of chemicals 19750101 |
| The antinicotinic effects of drugs with clinically useful sedative-antianxiety properties. | Pharmacology 19750101 |
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| Letter: Methyldopa-induced hypertension. | JAMA 19740204 |
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| A case of suspected Stokes-Adams attacks with trifluoperazine therapy. | Pennsylvania medicine 19721201 |
| An unusual response to chlorpromazine therapy. | The British journal of psychiatry : the journal of mental science 19721001 |
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| Flupenthixol and trifluoperazine: a double-blind investigation in the treatment of schizophrenics. | The British journal of psychiatry : the journal of mental science 19711101 |
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| Congenital malformations following phenothiazine administration during pregnancy. | Canadian Medical Association journal 19690125 |
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| Phenothiazines and diabetes in hospitalized women. | The American journal of psychiatry 19680101 |
| Despair, trifluoperazine, exercise, and temperature of 108 degrees F. | The American journal of psychiatry 19671101 |
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