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117-10-2 | 9,10-Anthracenedione, 1,8-dihydroxy-
CAS No: 117-10-2 Catalog No: AG000DHW MDL No:MFCD00001211
Product Description
Catalog Number:
AG000DHW
Chemical Name:
9,10-Anthracenedione, 1,8-dihydroxy-
CAS Number:
117-10-2
Molecular Formula:
C14H8O4
Molecular Weight:
240.2109
MDL Number:
MFCD00001211
IUPAC Name:
1,8-dihydroxyanthracene-9,10-dione
InChI:
InChI=1S/C14H8O4/c15-9-5-1-3-7-11(9)14(18)12-8(13(7)17)4-2-6-10(12)16/h1-6,15-16H
InChI Key:
QBPFLULOKWLNNW-UHFFFAOYSA-N
SMILES:
Oc1cccc2c1C(=O)c1c(C2=O)cccc1O
EC Number:
204-173-5
UNII:
Z4XE6IBF3V
UN Number:
2811
Properties
Complexity:
346
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
1
Defined Atom Stereocenter Count:
0
Defined Bond Stereocenter Count:
0
Exact Mass:
240.042g/mol
Formal Charge:
0
Heavy Atom Count:
18
Hydrogen Bond Acceptor Count:
4
Hydrogen Bond Donor Count:
2
Isotope Atom Count:
0
Molecular Weight:
240.214g/mol
Monoisotopic Mass:
240.042g/mol
Rotatable Bond Count:
0
Topological Polar Surface Area:
74.6A^2
Undefined Atom Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
XLogP3:
3.2
Literature
| Title | Journal |
|---|---|
| Comparative developmental toxicity of environmentally relevant oxygenated PAHs. | Toxicology and applied pharmacology 20130901 |
| Danthron triggers ROS and mitochondria-mediated apoptotic death in C6 rat glioma cells through caspase cascades, apoptosis-inducing factor and endonuclease G multiple signaling. | Neurochemical research 20120801 |
| Albopunctatone, an antiplasmodial anthrone-anthraquinone from the Australian ascidian Didemnum albopunctatum. | Journal of natural products 20120622 |
| Colorimetric and fluorescence sensing of Cu2+ in water using 1,8-dihydroxyanthraquinone-β-cyclodextrin complex with the assistance of ammonia. | Talanta 20120530 |
| Toxicology study of senna (CAS No. 8013-11-4) in C57BL/6NTAC Mice and toxicology and carcinogenesis study of senna in genetically modified C3B6.129F1/Tac-Trp53tm1Brd haploinsufficient mice (Feed Studies). | National Toxicology Program genetically modified model report 20120401 |
| DNA-binding, DNA cleavage and cytotoxicity studies of two anthraquinone derivatives. | Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20120215 |
| Comparison of dispersive liquid-liquid microextraction based on organic solvent and ionic liquid combined with high-performance liquid chromatography for the analysis of emodin and its metabolites in urine samples. | Journal of separation science 20120101 |
| Bioguided Fractionation Shows Cassia alata Extract to Inhibit Staphylococcus epidermidis and Pseudomonas aeruginosa Growth and Biofilm Formation. | Evidence-based complementary and alternative medicine : eCAM 20120101 |
| An overview of the evidence and mechanisms of herb-drug interactions. | Frontiers in pharmacology 20120101 |
| PCB 126 and other dioxin-like PCBs specifically suppress hepatic PEPCK expression via the aryl hydrocarbon receptor. | PloS one 20120101 |
| Exercise therapy for fibromyalgia. | Current pain and headache reports 20111001 |
| DNA-binding study of anthraquinone derivatives using chemometrics methods. | European journal of medicinal chemistry 20110701 |
| CFTR chloride channel as a molecular target of anthraquinone compounds in herbal laxatives. | Acta pharmacologica Sinica 20110601 |
| In vitro genotoxicity of danthron and its potential mechanism. | Mutation research 20110518 |
| Solid-phase extraction and ultra high-performance liquid chromatography tandem mass spectrometry analysis of the gastrointestinal absorption of emodin in different digestive segments of rats. | Journal of separation science 20110201 |
| Danthron functions as a retinoic X receptor antagonist by stabilizing tetramers of the receptor. | The Journal of biological chemistry 20110121 |
| Laxatives or methylnaltrexone for the management of constipation in palliative care patients. | The Cochrane database of systematic reviews 20110119 |
| Danthron, an anthraquinone derivative, induces DNA damage and caspase cascades-mediated apoptosis in SNU-1 human gastric cancer cells through mitochondrial permeability transition pores and Bax-triggered pathways. | Chemical research in toxicology 20110114 |
| Hypericins and thioredoxin reductase: Biochemical and docking studies disclose the molecular basis for effective inhibition by naphthodianthrones. | Bioorganic & medicinal chemistry 20110101 |
| In vitro study of the PLA2 inhibition and antioxidant activities of Aloe vera leaf skin extracts. | Lipids in health and disease 20110101 |
| Danthron inhibits murine WEHI-3 cells in vivo, and enhances macrophage phagocytosis and natural killer cell cytotoxic activity in leukemic mice. | In vivo (Athens, Greece) 20110101 |
| Intravitreal injection of methotrexate in an experimental rabbit model: determination of pharmacokinetics. | Indian journal of ophthalmology 20110101 |
| Drug nanoparticle formulation using ascorbic Acid derivatives. | Journal of drug delivery 20110101 |
| Phytochemical screening, antioxidant, and antimicrobial activities of the crude leaves' extract from Ipomoea batatas (L.) Lam. | Pharmacognosy magazine 20110101 |
| Danthron. | Report on carcinogens : carcinogen profiles 20110101 |
| Comparative study of intravenously administered clonidine and magnesium sulfate on hemodynamic responses during laparoscopic cholecystectomy. | Journal of anaesthesiology, clinical pharmacology 20110101 |
| A wireless sensor network for vineyard monitoring that uses image processing. | Sensors (Basel, Switzerland) 20110101 |
| Bioactive constituents and medicinal importance of genus Alnus. | Pharmacognosy reviews 20110101 |
| Synchrotron radiation linear dichroism (SRLD) investigation of the electronic transitions of quinizarin, chrysazin, and anthrarufin. | Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20100915 |
| Danthron induces DNA damage and inhibits DNA repair gene expressions in GBM 8401 human brain glioblastoma multiforms cells. | Neurochemical research 20100701 |
| 1,8-Dihydr-oxy-2,4,5,7-tetra-nitro-9,10-anthraquinone. | Acta crystallographica. Section E, Structure reports online 20100501 |
| Danthron induced apoptosis through mitochondria- and caspase-3-dependent pathways in human brain glioblastoma multiforms GBM 8401 cells. | Neurochemical research 20100301 |
| Potent inhibitor scaffold against Trypanosoma cruzi trans-sialidase. | Bioorganic & medicinal chemistry 20100215 |
| Anthraquinones danthron and quinizarin exert antiproliferative and antimetastatic activity on murine B16-F10 melanoma cells. | Anticancer research 20100201 |
| Enzymatic reduction of complex redox dyes using NADH-dependent reductase from Bacillus subtilis coupled with cofactor regeneration. | Applied microbiology and biotechnology 20100101 |
| 1,8-Bis(tos-yloxy)-9,10-anthraquinone. | Acta crystallographica. Section E, Structure reports online 20100101 |
| The coverage problem in video-based wireless sensor networks: a survey. | Sensors (Basel, Switzerland) 20100101 |
| Danthron inhibits the migration and invasion of human brain glioblastoma multiforme cells through the inhibition of mRNA expression of focal adhesion kinase, Rho kinases-1 and metalloproteinase-9. | Oncology reports 20091101 |
| Aloe-emodin-induced DNA fragmentation in the mouse in vivo comet assay. | Mutation research 20090801 |
| A 73-year-old man with long-term immobility presenting with abdominal pain. | PLoS medicine 20090701 |
| Differential inhibition of matrix metalloproteinases-2, -9, and -13 activities by selected anthraquinones. | Planta medica 20090301 |
| Structure-activity relationships of anthraquinones on the suppression of DNA-binding activity of the aryl hydrocarbon receptor induced by 2,3,7,8-tetrachlorodibenzo-p-dioxin. | Journal of bioscience and bioengineering 20090301 |
| A high-throughput approach for identification of novel general anesthetics. | PloS one 20090101 |
| Is senna laxative use associated to cathartic colon, genotoxicity, or carcinogenicity? | Journal of toxicology 20090101 |
| Dissociative photoionization mechanism of 1,8-dihydroxyanthraquinone: an experimental and theoretical study. | The journal of physical chemistry. A 20081030 |
| Correlation between reduction potentials and inhibitions of Epstein-Barr virus activation by anthraquinone derivatives. | Bioorganic & medicinal chemistry letters 20080715 |
| Study of interactions of anthraquinones with DNA using ethidium bromide as a fluorescence probe. | Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20080601 |
| On the interaction of the anthraquinone barbaloin with negatively charged DMPG bilayers. | Langmuir : the ACS journal of surfaces and colloids 20080415 |
| Solvent effect on the physical quenching of singlet molecular oxygen by p-quinones. | Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology 20080401 |
| Voltammetric Behavior of o-Nitrophenol and Damage to DNA. | International journal of molecular sciences 20080301 |
| Towards reconciling structure and function in the nuclear pore complex. | Histochemistry and cell biology 20080201 |
| Potential benefits of non-pharmacological therapies in fibromyalgia. | The open rheumatology journal 20080101 |
| Synthesis and antibacterial activity of some novel chiral fluorophoric biscyclic macrocycles. | Bioorganic & medicinal chemistry letters 20070915 |
| Simultaneous determination and pharmacokinetic studies of aloe emodin and chrysophanol in rats after oral administration of Da-Cheng-Qi decoction by high-performance liquid chromatography. | Biomedical chromatography : BMC 20070701 |
| Antiprotozoal activity of Senna racemosa. | Journal of ethnopharmacology 20070613 |
| Simultaneous quantification of five anthraquinones in rat plasma by high-performance liquid chromatography with fluorescence detection. | Biomedical chromatography : BMC 20070501 |
| Anthranoid laxatives influence the absorption of poorly permeable drugs in human intestinal cell culture model (Caco-2). | European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V 20070401 |
| The right dose for every sex. | Chromosoma 20070401 |
| Reactivity of aromatic amines with triplet 1,8-dihydroxyanthraquinone: a laser flash photolysis study. | Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20070101 |
| Initial in vitro screening approach to investigate the potential health and environmental hazards of Enviroxtrade mark - a nanoparticulate cerium oxide diesel fuel additive. | Particle and fibre toxicology 20070101 |
| Laxatives for the management of constipation in palliative care patients. | The Cochrane database of systematic reviews 20061018 |
| Intramolecular hydrogen bonding in 1,8-dihydroxyanthraquinone, 1-aminoanthraquinone, and 9-hydroxyphenalenone studied by picosecond time-resolved fluorescence spectroscopy in a supersonic jet. | The journal of physical chemistry. B 20061012 |
| Microbial transformation of amino- and hydroxyanthraquinones by Beauveria bassiana ATCC 7159. | Journal of natural products 20061001 |
| Defensive components in insect eggs: are anthraquinones produced during egg development? | Journal of chemical ecology 20060901 |
| Electrocoagulation of quinone pigments. | Molecules (Basel, Switzerland) 20060714 |
| Interaction of anthracene and its oxidative derivatives with human serum albumin. | Acta biochimica Polonica 20060101 |
| [Toxic effects of 1,8-dihydroxyanthraquinone on Daphnia magna]. | Ying yong sheng tai xue bao = The journal of applied ecology 20050601 |
| Electrochemical studies of danthron and the DNA-danthron interaction. | Biophysical chemistry 20050401 |
| Serially balanced designs for two sets of treatments. | Journal of biopharmaceutical statistics 20050101 |
| Oxoazabenzo[de]anthracenes conjugated to amino acids: synthesis and evaluation as DNA-binding antitumor agents. | Bioconjugate chemistry 20050101 |
| Growth responses of Cassia obtusifolia toward human intestinal bacteria. | Fitoterapia 20040701 |
| Danthron inhibits the neurotoxicity induced by various compounds causing oxidative damages including beta-amyloid (25-35) in primary cortical cultures. | Biological & pharmaceutical bulletin 20040501 |
| Inhibition of MAO A and B by some plant-derived alkaloids, phenols and anthraquinones. | Journal of ethnopharmacology 20040401 |
| Methotrexate for ankylosing spondylitis. | The Cochrane database of systematic reviews 20040101 |
| Danthron (1,8-dihydroxyanthraquinone). | Report on carcinogens : carcinogen profiles 20040101 |
| Emodin isolated from Cassia obtusifolia (Leguminosae) seed shows larvicidal activity against three mosquito species. | Journal of agricultural and food chemistry 20031217 |
| Circular dichroism imaging microscopy: application to enantiomorphous twinning in biaxial crystals of 1,8-dihydroxyanthraquinone. | Journal of the American Chemical Society 20031203 |
| Factors influencing constipation in advanced cancer patients: a prospective study of opioid dose, dantron dose and physical functioning. | Palliative medicine 20030701 |
| Dithranol reaction with nitroxide radicals in DMSO, a HPLC study. | Die Pharmazie 20030701 |
| Inhibition of protein kinase CK2 by anthraquinone-related compounds. A structural insight. | The Journal of biological chemistry 20030117 |
| Antimutagenic effects of black tea (World Blend) and its two active polyphenols theaflavins and thearubigins in Salmonella assays. | Phytotherapy research : PTR 20021101 |
| 1,8-Dihydroxyanthraquinone anchored on silica gel: synthesis and application as solid phase extractant for lead(II), zinc(II) and cadmium(II) prior to their determination by flame atomic absorption spectrometry. | Talanta 20021016 |
| Enrichment of iron(III), cobalt(II), nickel(II), and copper(II) by solid-phase extraction with 1,8-dihydroxyanthraquinone anchored to silica gel before their determination by flame atomic absorption spectrometry. | Analytical and bioanalytical chemistry 20021001 |
| Bryoanthrathiophene, a new antiangiogenic constituent from the bryozoan Watersipora subtorquata (d'Orbigny, 1852). | Journal of natural products 20020901 |
| [Studies on the chemical constituents of Shiraia bambusicola]. | Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20020901 |
| Cytotoxicity of rhein, the active metabolite of sennoside laxatives, is reduced by multidrug resistance-associated protein 1. | British journal of cancer 20020506 |
| Cytotoxicity of natural hydroxyanthraquinones: role of oxidative stress. | Zeitschrift fur Naturforschung. C, Journal of biosciences 20020101 |
| Danthron (1,8-dihydroxyanthraquinone). | Report on carcinogens : carcinogen profiles 20020101 |
| Adverse effects of laxatives. | Diseases of the colon and rectum 20010801 |
| Phytoestrogens from the roots of Polygonum cuspidatum (Polygonaceae): structure-requirement of hydroxyanthraquinones for estrogenic activity. | Bioorganic & medicinal chemistry letters 20010723 |
| Sequence-specific DNA damage induced by carcinogenic danthron and anthraquinone in the presence of Cu(II), cytochrome P450 reductase and NADPH. | Free radical research 20010601 |
| Antipsoriatic anthrones with modulated redox properties. 5. Potent inhibition of human keratinocyte growth, induction of keratinocyte differentiation, and reduced membrane damage by novel 10-arylacetyl-1,8-dihydroxy-9(10H)-anthracenones. | Journal of medicinal chemistry 20010301 |
| In vitro antiviral activity of the anthraquinone chrysophanic acid against poliovirus. | Antiviral research 20010301 |
| Heterocyclic substituted anthralin derivatives as inhibitors of keratinocyte growth and inducers of differentiation. | Bioorganic & medicinal chemistry letters 20010108 |
| Differential inhibition of HIV-1 preintegration complexes and purified integrase protein by small molecules. | Proceedings of the National Academy of Sciences of the United States of America 19960903 |
| Hydroxyquinones are competitive non-peptide inhibitors of HIV-1 proteinase. | Biochimica et biophysica acta 19951115 |
| Inhibitors of human immunodeficiency virus integrase. | Proceedings of the National Academy of Sciences of the United States of America 19930315 |
| Evaluation of the antiviral activity of anthraquinones, anthrones and anthraquinone derivatives against human cytomegalovirus. | Antiviral research 19920101 |
| Screening for new compounds with antiherpes activity. | Antiviral research 19841001 |
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