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116355-83-0

116355-83-0 | 1,2,3-Propanetricarboxylic acid, 1,1'-[(1S,2R)-1-[(2S,4R,9R,11S,12S)-12-amino-4,9,11-trihydroxy-2-methyltridecyl]-2-[(1R)-1-methylpentyl]-1,2-ethanediyl] ester, (2R,2'R)-

CAS No: 116355-83-0 Catalog No: AG000CAD MDL No:MFCD00133349

Product Description

Catalog Number:
AG000CAD
Chemical Name:
1,2,3-Propanetricarboxylic acid, 1,1'-[(1S,2R)-1-[(2S,4R,9R,11S,12S)-12-amino-4,9,11-trihydroxy-2-methyltridecyl]-2-[(1R)-1-methylpentyl]-1,2-ethanediyl] ester, (2R,2'R)-
CAS Number:
116355-83-0
Molecular Formula:
C34H61NO16
Molecular Weight:
739.8452
MDL Number:
MFCD00133349
IUPAC Name:
(2R)-2-[2-[(5R,6R,7S,9S,11R,16R,18S,19S)-19-amino-6-[(3R)-3,4-dicarboxybutanoyl]oxy-11,16,18-trihydroxy-5,9-dimethylicosan-7-yl]oxy-2-oxoethyl]butanedioic acid
InChI:
InChI=1S/C34H59NO15/c1-5-6-9-20(3)32(50-31(44)17-23(34(47)48)15-29(41)42)27(49-30(43)16-22(33(45)46)14-28(39)40)13-19(2)12-24(36)10-7-8-11-25(37)18-26(38)21(4)35/h19-27,32,36-38H,5-18,35H2,1-4H3,(H,39,40)(H,41,42)(H,45,46)(H,47,48)/t19-,20+,21-,22+,23+,24+,25+,26-,27-,32+/m0/s1
InChI Key:
UVBUBMSSQKOIBE-DSLOAKGESA-N
SMILES:
CCCC[C@H]([C@H](C(OC(=O)C[C@H](C(=O)O)CC(=O)O)C[C@H](C[C@@H](CCCC[C@H](C[C@@H]([C@@H](N)C)O)O)O)C)OC(=O)C[C@H](C(=O)O)CC(=O)O)C.O
UNII:
3ZZM97XZ32

Properties

Complexity:
1070  
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
10  
Defined Bond Stereocenter Count:
0
Exact Mass:
721.388g/mol
Formal Charge:
0
Heavy Atom Count:
50  
Hydrogen Bond Acceptor Count:
16  
Hydrogen Bond Donor Count:
8  
Isotope Atom Count:
0
Molecular Weight:
721.838g/mol
Monoisotopic Mass:
721.388g/mol
Rotatable Bond Count:
31  
Topological Polar Surface Area:
289A^2
Undefined Atom Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
XLogP3:
-0.5  

Literature

Title Journal
Individual and combined effects of Fusarium toxins on apoptosis in PK15 cells and the protective role of N-acetylcysteine. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20180101
The aflatoxin B(1) -fumonisin B(1) toxicity in BRL-3A hepatocytes is associated to induction of cytochrome P450 activity and arachidonic acid metabolism. Environmental toxicology 20170601
Evaluation of the cytotoxic properties, gene expression profiles and secondary signalling responses of cultured cells exposed to fumonisin B1, deoxynivalenol and zearalenone mycotoxins. Archives of toxicology 20170501
The ceramide inhibitor fumonisin B1 mitigates the pulmonary effects of low-dose diesel exhaust inhalation in mice. Ecotoxicology and environmental safety 20161001
An in vitro investigation on the cytotoxic and nuclear receptor transcriptional activity of the mycotoxins fumonisin B1 and beauvericin. Toxicology letters 20160822
Mycotoxins modify the barrier function of Caco-2 cells through differential gene expression of specific claudin isoforms: Protective effect of illite mineral clay. Toxicology 20160415
Fumonisin B1 induces autophagic cell death via activation of ERN1-MAPK8/9/10 pathway in monkey kidney MARC-145 cells. Archives of toxicology 20160401
Fumonisin B₁ inhibits apoptosis in HepG2 cells by inducing Birc-8/ILP-2. Toxicology letters 20150601
A prospective study of growth and biomarkers of exposure to aflatoxin and fumonisin during early childhood in Tanzania. Environmental health perspectives 20150201
Effects of aflatoxin B₁, fumonisin B₁ and their mixture on the aryl hydrocarbon receptor and cytochrome P450 1A induction. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20150101
Ceramide modulates pre-mRNA splicing to restore the expression of wild-type tumor suppressor p53 in deletion-mutant cancer cells. Biochimica et biophysica acta 20141101
Fumonisin B₁ modulates expression of human cytochrome P450 1b1 in human hepatoma (Hepg2) cells by repressing Mir-27b. Toxicology letters 20140516
Modulation of mucin mRNA (MUC5AC and MUC5B) expression and protein production and secretion in Caco-2/HT29-MTX co-cultures following exposure to individual and combined Fusarium mycotoxins. Toxicological sciences : an official journal of the Society of Toxicology 20140501
Nickel-induced cell death and survival pathways in cultured renal proximal tubule cells: roles of reactive oxygen species, ceramide and ABCB1. Archives of toxicology 20140401
Fumonisin B1 induces global DNA hypomethylation in HepG2 cells - An alternative mechanism of action. Toxicology 20140106
Individual and combined effects of Fusarium toxins on the mRNA expression of pro-inflammatory cytokines in swine jejunal epithelial cells. Toxicology letters 20130718
Development of a sensitive enzyme-linked immunosorbent assay for the detection of fumonisin B₁ in maize. Toxicon : official journal of the International Society on Toxinology 20121201
Experimental mycotoxic nephropathy in pigs provoked by a mouldy diet containing ochratoxin A and fumonisin B1. Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie 20121101
Co-exposure of Fusarium mycotoxins: in vitro myelotoxicity assessment on human hematopoietic progenitors. Toxicon : official journal of the International Society on Toxinology 20121101
A flow cytometry based competitive fluorescent microsphere immunoassay (CFIA) system for detecting up to six mycotoxins. Journal of immunological methods 20121031
Increased sphingoid base-1-phosphates and failure of neural tube closure after exposure to fumonisin or FTY720. Birth defects research. Part A, Clinical and molecular teratology 20121001
Toxic interaction between fumonisin B1 and moniliformin for cardiac lesions in Japanese quail. Avian diseases 20120901
Toxicity profile of commercially produced indigenous banana beer. Food additives & contaminants. Part A, Chemistry, analysis, control, exposure & risk assessment 20120801
Analysis of fumonisins B1 and B2 in spices and aromatic and medicinal herbs by HPLC-FLD with on-line post-column derivatization and positive confirmation by LC-MS/MS. The Analyst 20120707
Chlamydia trachomatis serovar L2 infection model using human lymphoid Jurkat cells. Microbial pathogenesis 20120701
Analysis of fumonisin B1 removal by microorganisms in co-occurrence with aflatoxin B1 and the nature of the binding process. International journal of food microbiology 20120601
Fumonisin FB1 treatment acts synergistically with methyl donor deficiency during rat pregnancy to produce alterations of H3- and H4-histone methylation patterns in fetuses. Molecular nutrition & food research 20120601
The critical role of spinal ceramide in the development of partial sciatic nerve ligation-induced neuropathic pain in mice. Biochemical and biophysical research communications 20120504
Fumonisin B1, a toxin produced by Fusarium verticillioides, modulates maize β-1,3-glucanase activities involved in defense response. Planta 20120501
Genetic variation of Fusarium oxysporum isolates forming fumonisin B(1) and moniliformin. Journal of applied genetics 20120501
Terpene alcohols inhibit de novo sphingolipid biosynthesis. Planta medica 20120301
C16 ceramide is crucial for triacylglycerol-induced apoptosis in macrophages. Cell death & disease 20120301
Distinct generation, pharmacology, and distribution of sphingosine 1-phosphate and dihydrosphingosine 1-phosphate in human neural progenitor cells. Neuropharmacology 20120201
Impact of fumonisin B1 on glutamate toxicity and low magnesium-induced seizure activity in neuronal primary culture. Neuroscience 20120127
Molecular and functional characterization of the ceramide synthase from Trypanosoma cruzi. Molecular and biochemical parasitology 20120101
Rapid determination of fumonisins B1 and B2 in corn by liquid chromatography-tandem mass spectrometry with ultrasonic extraction. Journal of chromatographic science 20120101
Characterization and comparison of Fumonisin B(1)-protein conjugates by six methods. International journal of molecular sciences 20120101
Regulation of interleukin-1alpha and tumor necrosis factor-alpha-induced interleukin-8 production by amnion-derived (WISH) cells. Clinical and experimental obstetrics & gynecology 20120101
Fusarium verticillioides from finger millet in Uganda. Food additives & contaminants. Part A, Chemistry, analysis, control, exposure & risk assessment 20120101
Kinetics of fumonisin B₁ formation in maize ears inoculated with Fusarium verticillioides. Food additives & contaminants. Part A, Chemistry, analysis, control, exposure & risk assessment 20120101
Fusarium infection of maize and maize-based products and exposure of a rural population to fumonisin B₁ in Limpopo Province, South Africa. Food additives & contaminants. Part A, Chemistry, analysis, control, exposure & risk assessment 20120101
Mycotoxin production by isolates of Fusarium lactis from greenhouse sweet pepper (Capsicum annuum). International journal of food microbiology 20111202
Fumonisin B1 and B2 occurrence in dried fig fruits (Ficus carica L.) under Meander Valley's climatic conditions and relationship with fruit quality. Food additives & contaminants. Part A, Chemistry, analysis, control, exposure & risk assessment 20111101
Reactive oxygen species as transducers of sphinganine-mediated cell death pathway. Plant signaling & behavior 20111001
MPK6, sphinganine and the LCB2a gene from serine palmitoyltransferase are required in the signaling pathway that mediates cell death induced by long chain bases in Arabidopsis. The New phytologist 20110901
Extrusion cooking with glucose supplementation of fumonisin-contaminated corn grits protects against nephrotoxicity and disrupted sphingolipid metabolism in rats. Molecular nutrition & food research 20110901
HXK1 regulates carbon catabolism, sporulation, fumonisin B₁ production and pathogenesis in Fusarium verticillioides. Microbiology (Reading, England) 20110901
Unique sphingomyelin patches are targets of a beta-cell-specific antibody. Journal of lipid research 20110901
Ceramide synthase 4 and de novo production of ceramides with specific N-acyl chain lengths are involved in glucolipotoxicity-induced apoptosis of INS-1 β-cells. The Biochemical journal 20110815
Enzyme characteristics of aminotransferase FumI of Sphingopyxis sp. MTA144 for deamination of hydrolyzed fumonisin B₁. Applied microbiology and biotechnology 20110801
Mycobiota and mycotoxins contamination in raw materials and finished feed intended for fattening pigs production in eastern Argentina. Veterinary research communications 20110801
Natural occurrence of fumonisins b1 and b2 in corn from three main production provinces in China. Journal of food protection 20110801
Fumonisin B1 toxicity in grower-finisher pigs: a comparative analysis of genetically engineered Bt corn and non-Bt corn by using quantitative dietary exposure assessment modeling. International journal of environmental research and public health 20110801
Reduction of fumonisin B₁ in corn grits by twin-screw extrusion. Journal of food science 20110801
Metabolic depletion of sphingolipids enhances the mobility of the human serotonin1A receptor. Biochemical and biophysical research communications 20110722
Efficacy of a mycotoxin binder against dietary fumonisin, deoxynivalenol, and zearalenone in rats. Journal of agricultural and food chemistry 20110713
Interaction of Bordetella bronchiseptica, Pasteurella multocida, and fumonisin B1 in the porcine respiratory tract as studied by computed tomography. Canadian journal of veterinary research = Revue canadienne de recherche veterinaire 20110701
Autophagy differentially controls plant basal immunity to biotrophic and necrotrophic pathogens. The Plant journal : for cell and molecular biology 20110601
Fumonisin B1 inhibits mitochondrial respiration and deregulates calcium homeostasis--implication to mechanism of cell toxicity. The international journal of biochemistry & cell biology 20110601
Surveys of rice sold in Canada for aflatoxins, ochratoxin A and fumonisins. Food additives & contaminants. Part A, Chemistry, analysis, control, exposure & risk assessment 20110601
Ceramide synthase-dependent ceramide generation and programmed cell death: involvement of salvage pathway in regulating postmitochondrial events. The Journal of biological chemistry 20110506
Effects of fumonisin B1 on HLA class I antigen presentation and processing pathway in GES-1 cells in vitro. Human & experimental toxicology 20110501
A single prior bout of exercise protects against palmitate-induced insulin resistance despite an increase in total ceramide content. American journal of physiology. Regulatory, integrative and comparative physiology 20110501
Comparison of methods and optimisation of the analysis of fumonisins B₁ and B₂ in masa flour, an alkaline cooked corn product. Food additives & contaminants. Part A, Chemistry, analysis, control, exposure & risk assessment 20110501
Aflatoxin B1 and fumonisin B1 affect the oxidative status of bovine peripheral blood mononuclear cells. Toxicology in vitro : an international journal published in association with BIBRA 20110401
Field control of Fusarium ear rot, Ostrinia nubilalis (Hübner), and fumonisins in maize kernels. Pest management science 20110401
Proteomic analysis of extracellular ATP-regulated proteins identifies ATP synthase beta-subunit as a novel plant cell death regulator. Molecular & cellular proteomics : MCP 20110301
Fumonisin B1 as a urinary biomarker of exposure in a maize intervention study among South African subsistence farmers. Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 20110301
Preferential involvement of both ROS and ceramide in fenretinide-induced apoptosis of HL60 rather than NB4 and U937 cells. Biochemical and biophysical research communications 20110211
In vitro inhibitory effect of tetrahydrocurcuminoids on Fusarium proliferatum growth and fumonisin B₁ biosynthesis. Food additives & contaminants. Part A, Chemistry, analysis, control, exposure & risk assessment 20110201
Protein synthesis in plasma cells is regulated by crosstalk between endoplasmic reticulum stress and mTOR signaling. European journal of immunology 20110201
Molecular characterization and fumonisin production by Fusarium verticillioides isolated from corn grains of different geographic origins in Brazil. International journal of food microbiology 20110131
Antifumonisin activity of natural phenolic compounds A structure-property-activity relationship study. International journal of food microbiology 20110131
The LSD1-interacting protein GILP is a LITAF domain protein that negatively regulates hypersensitive cell death in Arabidopsis. PloS one 20110101
Assessment of fumonisins B1 and B2 levels in commercial maize-based food products by liquid chromatography with fluorimetric detection and postcolumn chemical derivatization. Journal of food science 20110101
Determination of fumonisins B₁ and B₂ in maize food products by a new analytical method based on high-performance liquid chromatography and fluorimetric detection with post-column derivatization. Methods in molecular biology (Clifton, N.J.) 20110101
Mitochondrial ceramide-rich macrodomains functionalize Bax upon irradiation. PloS one 20110101
Involvement of the sphingolipid ceramide in heat-shock-induced apoptosis of bovine oocytes. Reproduction, fertility, and development 20110101
Toxic effects induced by mycotoxin fumonisin B1 on equine spermatozoa: assessment of viability, sperm chromatin structure stability, ROS production and motility. Toxicology in vitro : an international journal published in association with BIBRA 20101201
Identification of the first fumonisin mycotoxins with three acyl groups by ESI-ITMS and ESI-TOFMS following RP-HPLC separation: palmitoyl, linoleoyl and oleoyl EFB₁ fumonisin isomers from a solid culture of Fusarium verticillioides. Food additives & contaminants. Part A, Chemistry, analysis, control, exposure & risk assessment 20101201
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Inhibitory effect of ethanol on AMPK phosphorylation is mediated in part through elevated ceramide levels. American journal of physiology. Gastrointestinal and liver physiology 20100601
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Detergent-resistant microdomains determine the localization of sigma-1 receptors to the endoplasmic reticulum-mitochondria junction. Molecular pharmacology 20100401
Effects of aflatoxin B(1) and fumonisin B(1) on blood biochemical parameters in broilers. Toxins 20100401
Metabolic depletion of sphingolipids impairs ligand binding and signaling of human serotonin1A receptors. Biochemistry 20100323
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Degradation of fumonisin B1 by the consecutive action of two bacterial enzymes. Journal of biotechnology 20100115
Production and characterization of monoclonal antibody and its recombinant single chain variable fragment specific for a food-born mycotoxin, fumonisin B1. Bioprocess and biosystems engineering 20100101
Mycotoxic nephropathy in Bulgarian pigs and chickens: complex aetiology and similarity to Balkan endemic nephropathy. Food additives & contaminants. Part A, Chemistry, analysis, control, exposure & risk assessment 20100101
Detection and characterization of twenty-eight isomers of fumonisin B1 (FB1) mycotoxin in a solid rice culture infected with Fusarium verticillioides by reversed-phase high-performance liquid chromatography/electrospray ionization time-of-flight and ion trap mass spectrometry. Rapid communications in mass spectrometry : RCM 20100101
Effects of aflatoxin B(1) and fumonisin B(1) on the viability and induction of apoptosis in rat primary hepatocytes. International journal of molecular sciences 20100101
Determination of fumonisins B1 and B2 in corn by LC/MS with immunoaffinity column cleanup: interlaboratory study. Journal of AOAC International 20100101
Enhancement of solubility in Escherichia coli and purification of an aminotransferase from Sphingopyxis sp. MTA144 for deamination of hydrolyzed fumonisin B(1). Microbial cell factories 20100101
Importance of lipid rafts for lysophosphatidylcholine-induced caspase-1 activation and reactive oxygen species generation. Cellular immunology 20100101
Determination of fumonisin B1 in botanical roots by liquid chromatography with fluorescence detection: single-laboratory validation. Journal of AOAC International 20100101
Screening and initial binding assessment of fumonisin b(1) aptamers. International journal of molecular sciences 20100101
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Reproductive and sphingolipid metabolic effects of fumonisin B(1) and its alkaline hydrolysis product in LM/Bc mice: hydrolyzed fumonisin B(1) did not cause neural tube defects. Toxicological sciences : an official journal of the Society of Toxicology 20091201
Fumonisin B1 neurotoxicity in young carp (Cyprinus carpio L.). Arhiv za higijenu rada i toksikologiju 20091201
Regulation of primary cilia formation by ceramide. Journal of lipid research 20091001
Ceramide mediates inhibition of the AKT/eNOS signaling pathway by palmitate in human vascular endothelial cells. Medical science monitor : international medical journal of experimental and clinical research 20090901
Glycosphingolipid requirements for endosome-to-Golgi transport of Shiga toxin. Traffic (Copenhagen, Denmark) 20090701
Inhibition of ceramide biosynthesis ameliorates pathological consequences of spinal cord injury. Shock (Augusta, Ga.) 20090601
Acute toxicity of a single gavage dose of fumonisin B1 in rabbits. Chemico-biological interactions 20090515
Fumonisin B(1) production by Fusarium proliferatum strains isolated from Allium fistulosum plants and seeds in Japan. Letters in applied microbiology 20090501
Reduction of fumonisin B1 in extruded corn breakfast cereals with salt, malt and sugar in their formulation. Food additives & contaminants. Part A, Chemistry, analysis, control, exposure & risk assessment 20090401
Cell wall component and mycotoxin moieties involved in the binding of fumonisin B1 and B2 by lactic acid bacteria. Journal of applied microbiology 20090301
Ceramide synthase 6 modulates TRAIL sensitivity and nuclear translocation of active caspase-3 in colon cancer cells. Oncogene 20090226
Ceramide synthase inhibition by fumonisin B1 causes accumulation of 1-deoxysphinganine: a novel category of bioactive 1-deoxysphingoid bases and 1-deoxydihydroceramides biosynthesized by mammalian cell lines and animals. The Journal of biological chemistry 20090220
Fumonisin b1 reduces the development of multiple organ failure induced by zymosan in mice. Shock (Augusta, Ga.) 20090201
R(+)-methanandamide-induced apoptosis of human cervical carcinoma cells involves a cyclooxygenase-2-dependent pathway. Pharmaceutical research 20090201
Natural occurrence of fumonisin B1 in dried figs as an unexpected hazard. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20090201
Occurrence of fumonisin B(1) in corn from the main corn-producing areas of China. Mycopathologia 20090101
Inhibition of fengycins on the production of fumonisin B1 from Fusarium verticillioides. Letters in applied microbiology 20090101
Chemoprotective properties of rooibos (Aspalathus linearis), honeybush (Cyclopia intermedia) herbal and green and black (Camellia sinensis) teas against cancer promotion induced by fumonisin B1 in rat liver. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20090101
Multiresidue mycotoxin analysis in corn grain by column high-performance liquid chromatography with postcolumn photochemical and chemical derivatization: single-laboratory validation. Journal of AOAC International 20090101
The food contaminant fumonisin B(1) reduces the maturation of porcine CD11R1(+) intestinal antigen presenting cells and antigen-specific immune responses, leading to a prolonged intestinal ETEC infection. Veterinary research 20090101
Incomplete recoveries of fumonisins present in naturally contaminated corn foods from an immunoaffinity column. Journal of AOAC International 20090101
A review of the toxic effects and mechanisms of action of fumonisin B1. Human & experimental toxicology 20081101
Vorinostat and sorafenib increase ER stress, autophagy and apoptosis via ceramide-dependent CD95 and PERK activation. Cancer biology & therapy 20081001
Involvement of phosphatidylinositol-3 kinase/AKT/PKCzeta/lambda pathway in the effect of palmitate on glucose-induced insulin secretion. Pancreas 20081001
Reduced toxicity of fumonisin B1 in corn grits by single-screw extrusion. Journal of food protection 20081001
Sphingolipid metabolism is a crucial determinant of cellular fate in nonstimulated proliferating Madin-Darby canine kidney (MDCK) cells. The Journal of biological chemistry 20080912
Cancer initiating properties of fumonisin B1 in a short-term rat liver carcinogenesis assay. Toxicology 20080904
Immune effects of four Fusarium-toxins (FB1, ZEA, NIV, DON) on the proliferation of Jurkat cells and porcine lymphocytes: in vitro study. Veterinary research communications 20080901
Development of a new analytical method for the determination of fumonisins B1 and B2 in food products based on high performance liquid chromatography and fluorimetric detection with post-column derivatization. Journal of chromatography. A 20080829
AMPK activator, AICAR, inhibits palmitate-induced apoptosis in osteoblast. Bone 20080801
Ceramide is responsible for the failure of compensatory nerve sprouting in apolipoprotein E knock-out mice. The Journal of neuroscience : the official journal of the Society for Neuroscience 20080730
A role for ceramide in driving cancer cell resistance to doxorubicin. FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20080701
[Etiology of iodinated radiocontrast nephrotoxicity and its attenuation by beraprost]. Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 20080701
Effects of four Fusarium toxins (fumonisin B(1), alpha-zearalenol, nivalenol and deoxynivalenol) on porcine whole-blood cellular proliferation. Toxicon : official journal of the International Society on Toxinology 20080701
Reduction in fusarium toxin levels in corn silage with low dry matter and storage time. Journal of agricultural and food chemistry 20080625
Role of AREA, a regulator of nitrogen metabolism, during colonization of maize kernels and fumonisin biosynthesis in Fusarium verticillioides. Fungal genetics and biology : FG & B 20080601
Individual and combined effects of fumonisin b1 and moniliformin on clinicopathological and cell-mediated immune response in Japanese quail. Poultry science 20080601
Kunitz trypsin inhibitor: an antagonist of cell death triggered by phytopathogens and fumonisin b1 in Arabidopsis. Molecular plant 20080501
Reduction of fumonisin B1 in corn grits by single-screw extrusion. Journal of agricultural and food chemistry 20080409
Cytotoxicity and apoptosis induced by fumonisin B(1), beauvericin and ochratoxin A in porcine kidney PK15 cells: effects of individual and combined treatment. Archives of toxicology 20080401
Cannabinoids inhibit glioma cell invasion by down-regulating matrix metalloproteinase-2 expression. Cancer research 20080315
Mycotoxins in breakfast cereals from the Canadian retail market: a 3-year survey. Food additives & contaminants. Part A, Chemistry, analysis, control, exposure & risk assessment 20080301
Association between tortilla consumption and human urinary fumonisin B1 levels in a Mexican population. Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 20080301
Ceramide: a key signaling molecule in a Guinea pig model of allergic asthmatic response and airway inflammation. The Journal of pharmacology and experimental therapeutics 20080201
The mycotoxin fumonisin B1 inhibits eukaryotic protein synthesis: in vitro and in vivo studies. Mycopathologia 20080101
Inhibitory effect of cyclic terpenes (limonene, menthol, menthone and thymol) on Fusarium verticillioides MRC 826 growth and fumonisin B1 biosynthesis. Toxicon : official journal of the International Society on Toxinology 20080101
Functional characterization of Fusarium verticillioides CPP1, a gene encoding a putative protein phosphatase 2A catalytic subunit. Microbiology (Reading, England) 20080101
Cytotoxicity of fumonisin B(1) in spheroid and monolayer cultures of rat hepatocytes. Drug and chemical toxicology 20080101
Effects of oral administration of aflatoxin B1 and fumonisin B1 in rabbits (Oryctolagus cuniculus). Chemico-biological interactions 20071215
Mycotoxin fumonisin B1 alters cellular redox balance and signalling pathways in rat liver and kidney. Toxicology 20071205
Involvement of sphingoid bases in mediating reactive oxygen intermediate production and programmed cell death in Arabidopsis. Cell research 20071201
Recycling of sphingosine is regulated by the concerted actions of sphingosine-1-phosphate phosphohydrolase 1 and sphingosine kinase 2. The Journal of biological chemistry 20071123
Validation of fumonisin biomarkers in F344 rats. Toxicology and applied pharmacology 20071115
Fumonisin B2 production by Aspergillus niger. Journal of agricultural and food chemistry 20071114
The mycobiota and toxicity of equine feeds. Veterinary research communications 20071101
Folate receptor and human reduced folate carrier expression in HepG2 cell line exposed to fumonisin B1 and folate deficiency. Carcinogenesis 20071101
[Association between murine double minute 2 expression and AngII and ceramide induced endothelial cells apoptosis]. Zhonghua xin xue guan bing za zhi 20071001
Cadmium-induced ceramide formation triggers calpain-dependent apoptosis in cultured kidney proximal tubule cells. American journal of physiology. Cell physiology 20070901
Fumonisins production by Fusarium proliferatum strains isolated from asparagus crown. Mycopathologia 20070901
The involvement of oxidative stress in ochratoxin A and fumonisin B1 toxicity in rats. Molecular nutrition & food research 20070901
Survey of maize from south-western Nigeria for zearalenone, alpha- and beta-zearalenols, fumonisin B1 and enniatins produced by Fusarium species. Food additives and contaminants 20070901
Hydrolyzed fumonisins HFB1 and HFB2 are acylated in vitro and in vivo by ceramide synthase to form cytotoxic N-acyl-metabolites. Molecular nutrition & food research 20070901
Pathologic changes in extrahepatic organs and agglutinin response to Salmonella Gallinarum infection in Japanese quail fed Fusarium verticillioides culture material containing known levels of fumonisin B1. Avian diseases 20070901
Occurrence of fumonisins B1 and B2 in broa, typical Portuguese maize bread. International journal of food microbiology 20070815
Elevation of sphingoid base 1-phosphate as a potential contributor to hepatotoxicity in fumonisin B1-exposed mice. Archives of pharmacal research 20070801
Mechanism of inhibition of sequestration of protein kinase C alpha/betaII by ceramide. Roles of ceramide-activated protein phosphatases and phosphorylation/dephosphorylation of protein kinase C alpha/betaII on threonine 638/641. The Journal of biological chemistry 20070713
Use of formalin-fixed tissues to determine fumonisin B1-induced sphingolipid alterations in swine. Journal of veterinary diagnostic investigation : official publication of the American Association of Veterinary Laboratory Diagnosticians, Inc 20070701
Fumonisin B1 exposure and its selective effect on porcine jejunal segment: sphingolipids, glycolipids and trans-epithelial passage disturbance. Biochemical pharmacology 20070630
[Evaluation of the cytotoxicity of aflatoxin and fumonisin in swine intestinal cells]. Revista iberoamericana de micologia 20070601
Depletion of the lipid raft constituents, sphingomyelin and ganglioside, decreases serotonin binding at human 5-HT7(a) receptors in HeLa cells. Acta physiologica (Oxford, England) 20070501
Fumonisin disruption of ceramide biosynthesis in maize roots and the effects on plant development and Fusarium verticillioides-induced seedling disease. Journal of agricultural and food chemistry 20070418
Fumonisin B(1): oxidative status and DNA damage in rats. Toxicology 20070411
Altered lipid parameters in hepatic subcellular membrane fractions induced by fumonisin B1. Lipids 20070401
Occurrence of fumonisins B1 and B2 in Portuguese maize and maize-based foods intended for human consumption. Food additives and contaminants 20070401
Screening of fermentative bacteria for their ability to bind and biotransform deoxynivalenol, zearalenone and fumonisins in an in vitro simulated corn silage model. Food additives and contaminants 20070401
In vitro microbial metabolism of fumonisin B1. Food additives and contaminants 20070401
The influence of modified atmospheres and their interaction with water activity on the radial growth and fumonisin B(1) production of Fusarium verticillioides and F. proliferatum on corn. Part I: the effect of initial headspace carbon dioxide concentration. International journal of food microbiology 20070310
Effects of combinations of Fusarium mycotoxins on the inhibition of macromolecular synthesis, malondialdehyde levels, DNA methylation and fragmentation, and viability in Caco-2 cells. Toxicon : official journal of the International Society on Toxinology 20070301
Lipid peroxidation and glutathione levels in porcine kidney PK15 cells after individual and combined treatment with fumonisin B(1), beauvericin and ochratoxin A. Basic & clinical pharmacology & toxicology 20070301
The influence of modified atmospheres and their interaction with water activity on the radial growth and fumonisin B(1) production of Fusarium verticillioides and F. proliferatum on corn. Part II: The effect of initial headspace oxygen concentration. International journal of food microbiology 20070215
Inducible nitric oxide has protective effect on fumonisin B1 hepatotoxicity in mice via modulation of sphingosine kinase. Toxicology 20070105
Caspase-dependent and -independent induction of phosphatidylserine externalization during apoptosis in human renal carcinoma Cak(1)-1 and A-498 cells. Toxicology 20070105
Natural occurrence of Fusarium species, fumonisin production by toxigenic strains, and concentrations of fumonisins B1, and B2 in conventional and organic maize grown in Spain. Journal of food protection 20070101
Involvement of glycogen synthase kinase-3beta in palmitate-induced human umbilical vein endothelial cell apoptosis. Journal of vascular research 20070101
Lipofection of insulin-producing RINm5F cells: methodological improvements. Journal of liposome research 20070101
Mechanism of homocysteine-induced Rac1/NADPH oxidase activation in mesangial cells: role of guanine nucleotide exchange factor Vav2. Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 20070101
Cholesterol depletion reduces serotonin binding and signaling via human 5-HT(7(a)) receptors. European journal of pharmacology 20061215
Interactive effects of fumonisin B1 and alpha-zearalenol on proliferation and cytokine expression in Jurkat T cells. Toxicology in vitro : an international journal published in association with BIBRA 20061201
Ceramide synthase inhibition by fumonisin B1 treatment activates sphingolipid-metabolizing systems in mouse liver. Toxicological sciences : an official journal of the Society of Toxicology 20061201
Elevation of sphinganine 1-phosphate as a predictive biomarker for fumonisin exposure and toxicity in mice. Journal of toxicology and environmental health. Part A 20061201
Mycobiota in poultry feeds and natural occurrence of aflatoxins, fumonisins and zearalenone in the Rio de Janeiro State, Brazil. Mycopathologia 20061101
Co-occurrence of aflatoxin B1, fumonisin B1, ochratoxin A and zearalenone in cereals and peanuts from Côte d'Ivoire. Food additives and contaminants 20061001
Peroxidase-dependent apoplastic oxidative burst in Arabidopsis required for pathogen resistance. The Plant journal : for cell and molecular biology 20060901
Biocontrol of aflatoxins B1, B2, G1, G2, and fumonisin B1 with 6,7-dimethoxycoumarin, a phytoalexin from Citrus sinensis. Journal of food protection 20060901
Fumonisin B1-induced apoptosis in neuroblastoma, glioblastoma and hypothalamic cell lines. Toxicology 20060815
Multiplex PCR-based detection of potential fumonisin-producing Fusarium in traditional African vegetables. Environmental toxicology 20060801
Effect of fumonisins on macrophage immune functions and gene expression of cytokines in broilers. Archives of animal nutrition 20060801
Fumonisin production and bioavailability to maize seedlings grown from seeds inoculated with Fusarium verticillioides and grown in natural soils. Journal of agricultural and food chemistry 20060726
Fumonisin concentration and ceramide synthase inhibitory activity of corn, masa, and tortilla chips. Journal of toxicology and environmental health. Part A 20060701
Effects of feeding Fusarium verticillioides (formerly Fusarium moniliforme) culture material containing known levels of fumonisin B1 in Japanese quail (Coturnix coturnix japonica). Poultry science 20060701
Sex-related differences in the immune response of weanling piglets exposed to low doses of fumonisin extract. The British journal of nutrition 20060601
Mice lacking both TNFalpha receptors show increased constitutive expression of IFNgamma: a possible reason for lack of protection from fumonisin B1 hepatotoxicity. Cytokine 20060601
The role of tumor necrosis factor alpha and the peroxisome proliferator-activated receptor alpha in modulating the effects of fumonisin in mouse liver. Toxicology 20060515
Expression of the Arabidopsis high-affinity hexose transporter STP13 correlates with programmed cell death. FEBS letters 20060417
Ceramide is a mediator of apoptosis in retina photoreceptors. Investigative ophthalmology & visual science 20060401
Fumonisin production in rice cultures of Fusarium verticillioides under different incubation conditions using an optimized analytical method. Food microbiology 20060401
Effects of fumonisins on liver and kidney sphinganine and the sphinganine to sphingosine ratio during chronic exposure in ducks. Chemico-biological interactions 20060310
Serum sphinganine and the sphinganine to sphingosine ratio as a biomarker of dietary fumonisins during chronic exposure in ducks. Chemico-biological interactions 20060310
Determination of fumonisins B1 and B2 in Portuguese maize and maize-based samples by HPLC with fluorescence detection. Analytical and bioanalytical chemistry 20060301
Fck1, a C-type cyclin-dependent kinase, interacts with Fcc1 to regulate development and secondary metabolism in Fusarium verticillioides. Fungal genetics and biology : FG & B 20060301
The CLN9 protein, a regulator of dihydroceramide synthase. The Journal of biological chemistry 20060203
Toxic effects of fumonisin in mouse liver are independent of the peroxisome proliferator-activated receptor alpha. Toxicological sciences : an official journal of the Society of Toxicology 20060101
Involvement of de novo ceramide synthesis in radiocontrast-induced renal tubular cell injury. Kidney international 20060101
S-adenosylmethionine or 5'-methylthioadenosine are unable to prevent fumonisin B1 hepatotoxicity in mice despite increased oxidation in liver. Journal of applied toxicology : JAT 20060101
Fumonisin B1 induces necrotic cell death in BV-2 cells and murine cultured astrocytes and is antiproliferative in BV-2 cells while N2A cells and primary cortical neurons are resistant. Neurotoxicology 20051201
Lupus-prone NZBWF1/J mice, defective in cytokine signaling, are resistant to fumonisin hepatotoxicity despite accumulation of liver sphinganine. Toxicology 20051201
Toxic effects of Ustilago maydis and fumonisin B1 in rats. Acta pharmaceutica (Zagreb, Croatia) 20051201
Mould contamination and co-occurrence of mycotoxins in maize grain in Croatia. Acta pharmaceutica (Zagreb, Croatia) 20051201
Individual and combined effects of Fusarium moniliforme culture material, containing known levels of fumonisin B1, and Salmonella gallinarum infection on liver of Japanese quail. Avian diseases 20051201
Amylopectin induces fumonisin B1 production by Fusarium verticillioides during colonization of maize kernels. Molecular plant-microbe interactions : MPMI 20051201
Fumonisin production by Fusarium verticillioides strains isolated from maize in Mexico and development of a polymerase chain reaction to detect potential toxigenic strains in grains. Journal of agricultural and food chemistry 20051102
Mechanisms of sphingosine and sphingosine 1-phosphate generation in human platelets. Journal of lipid research 20051101
Extracellular ATP functions as an endogenous external metabolite regulating plant cell viability. The Plant cell 20051101
Mechanism of action of sphingolipids and their metabolites in the toxicity of fumonisin B1. Progress in lipid research 20051101
Identification and heritability of fumonisin insensitivity in Zea mays. Phytochemistry 20051001
Reduction of fumonisin B1 and zearalenone by lactic acid bacteria in fermented maize meal. Journal of food protection 20051001
Vacuolar processing enzyme is essential for mycotoxin-induced cell death in Arabidopsis thaliana. The Journal of biological chemistry 20050923
Comparative study of cytotoxicity and oxidative stress induced by deoxynivalenol, zearalenone or fumonisin B1 in human intestinal cell line Caco-2. Toxicology 20050915
Inhibition of tumor necrosis factor alpha signaling by anti-tumor necrosis factor alpha antibodies and pentoxifylline is unable to prevent fumonisin hepatotoxicity in mice. Toxicon : official journal of the International Society on Toxinology 20050915
Endotoxin exposure alters brain and liver effects of fumonisin B1 in BALB/c mice: implication of blood brain barrier. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20050901
Effects of ceramide inhibition on experimental radiation-induced oral mucositis. Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics 20050901
Toxigenic potential of Fusarium species isolated from non-harvested maize. Arhiv za higijenu rada i toksikologiju 20050901
Activated carbon does not prevent the toxicity of culture material containing fumonisin B1 when fed to weanling piglets. Journal of animal science 20050801
[Spontaneous and induced programmed cell death in suspension cell cultures of cotton (Gossypium hirsutum L.)]. Shi yan sheng wu xue bao 20050801
In vitro study with Caco-2 cells on fumonisin B1: aminopentol intestinal passage and role of P-glycoprotein. Veterinary research communications 20050801
Maternal fumonisin exposure and risk for neural tube defects: mechanisms in an in vivo mouse model. Birth defects research. Part A, Clinical and molecular teratology 20050701
Occurrence of fumonisins B1 and B2 in asparagus from Shandong province, PR China. Food additives and contaminants 20050701
Fumonisin B1, fumonisin B2, zearalenone and ochratoxin A contamination of maize in Croatia. Food additives and contaminants 20050701
Myriocin prevents fumonisin B1-induced sphingoid base accumulation in mice liver without ameliorating hepatotoxicity. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20050601
Comparative pathologic changes in broiler chicks on feed amended with Fusarium proliferatum culture material or purified fumonisin B1 and moniliformin. Mycopathologia 20050601
Effects of Fusarium moniliforme culture material containing known levels of fumonisin B1 on progress of Salmonella Gallinarum infection in Japanese quail: clinical signs and hematologic studies. Avian diseases 20050601
Fumonisin B-glucose reaction products are less toxic when fed to swine. Journal of agricultural and food chemistry 20050518
Simple method for the simultaneous isolation and determination of fumonisin B1 and its metabolite aminopentol-1 in swine liver by liquid chromatography--fluorescence detection. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20050505
Cytotoxicity of Fusarium mycotoxins to mammalian cell cultures as determined by the MTT bioassay. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20050501
Ceramide upregulation causes pulmonary cell apoptosis and emphysema-like disease in mice. Nature medicine 20050501
Rhizobacteria and their potential to control Fusarium verticillioides: effect of maize bacterisation and inoculum density. Antonie van Leeuwenhoek 20050401
Absorption of fumonisin B1 and aminopentol on an in vitro model of intestinal epithelium; the role of P-glycoprotein. Toxicon : official journal of the International Society on Toxinology 20050301
Fumonisin B1-induced neurodegeneration in mice after intracerebroventricular infusion is concurrent with disruption of sphingolipid metabolism and activation of proinflammatory signaling. Neurotoxicology 20050301
Production of a single-chain variable fragment antibody against fumonisin B1. Journal of agricultural and food chemistry 20050223
Fumonisin B1 hepatotoxicity in mice is attenuated by depletion of Kupffer cells by gadolinium chloride. Toxicology 20050201
Occurrence of mycotoxin in Farro samples from southern Italy. Journal of food protection 20050201
Fate of mycotoxins in cereals during extrusion cooking: a review. Food additives and contaminants 20050201
Selective inhibition of juxtanuclear translocation of protein kinase C betaII by a negative feedback mechanism involving ceramide formed from the salvage pathway. The Journal of biological chemistry 20050128
Inhibition of sphingolipid biosynthesis decreases phosphorylated ERK2 in LLC-PK1 cells. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20050101
Chronic effects of fumonisin B1 on ducks. Poultry science 20050101
Biocontrol of Bacillus subtilis against Fusarium verticillioides in vitro and at the maize root level. Research in microbiology 20050101
Development of a liquid chromatography/tandem mass spectrometry method for the quantification of fumonisin B1, B2 and B3 in cornflakes. Rapid communications in mass spectrometry : RCM 20050101
In vitro influence of bacterial mixtures on Fusarium verticillioides growth and fumonisin B1 production: effect of seeds treatment on maize root colonization. Letters in applied microbiology 20050101
Sphingosine kinase activity confers resistance to apoptosis by fumonisin B1 in human embryonic kidney (HEK-293) cells. Chemico-biological interactions 20041230
Glucose reaction with fumonisin B1 partially reduces its toxicity in swine. Journal of agricultural and food chemistry 20041215
Altered de novo sphingolipid biosynthesis is involved in the serum deprivation-induced cell death in LLC-PK1 cells. Journal of toxicology and environmental health. Part A 20041201
Field observations in pigs exposed to fumonisin B1 contaminated feed. Veterinary and human toxicology 20041201
Investigations into the etiology of neural tube defects. Birth defects research. Part C, Embryo today : reviews 20041201
Analysis of heat-processed corn foods for fumonisins and bound fumonisins. Food additives and contaminants 20041201
Homocysteine activates NADH/NADPH oxidase through ceramide-stimulated Rac GTPase activity in rat mesangial cells. Kidney international 20041101
Screening procedures for selecting rhizobacteria with biocontrol effects upon Fusarium verticillioides growth and fumonisin B1 production. Research in microbiology 20041101
Utility of the polymerase chain reaction-restriction fragment length polymorphisms of the intergenic spacer region of the rDNA for characterizing Gibberella fujikuroi isolates. Systematic and applied microbiology 20041101
Trends of fumonisin contamination and animal intoxication through monitoring 1991 to 1997 corn crop in the State of Paraná, Brazil. Mycopathologia 20041101
Augmented fumonisin B1 toxicity in co-cultures: evidence for crosstalk between macrophages and non-parenchymatous liver epithelial cells involving proinflammatory cytokines. Toxicology 20041015
Fumonisin B1-induced toxicity and oxidative damage in U-118MG glioblastoma cells. Toxicology 20041001
[Analysis of fumonisin B1 and B2 in beer and raw materials of beer by liquid chromatography/tandem mass spectrometry]. Shokuhin eiseigaku zasshi. Journal of the Food Hygienic Society of Japan 20041001
Aromatic plants essential oils activity on Fusarium verticillioides Fumonisin B(1) production in corn grain. Mycopathologia 20041001
Subcellular compartmentalization of ceramide metabolism: MAM (mitochondria-associated membrane) and/or mitochondria? The Biochemical journal 20040901
Dual effects of IGFBP-3 on endothelial cell apoptosis and survival: involvement of the sphingolipid signaling pathways. FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20040901
Synergistic effects of fumonisin B1 and ochratoxin A: are in vitro cytotoxicity data predictive of in vivo acute toxicity? Toxicology 20040901
Gangliosides link the acidic sphingomyelinase-mediated induction of ceramide to 12-lipoxygenase-dependent apoptosis of neuroblastoma in response to fenretinide. Journal of the National Cancer Institute 20040901
Oxidative stress induced by fumonisin B1 in continuous human and rodent neural cell cultures. Free radical research 20040901
Cannabinoids inhibit the vascular endothelial growth factor pathway in gliomas. Cancer research 20040815
Role of sphingosine-1-phosphate phosphatase 1 in epidermal growth factor-induced chemotaxis. The Journal of biological chemistry 20040813
Silymarin protects against liver damage in BALB/c mice exposed to fumonisin B1 despite increasing accumulation of free sphingoid bases. Toxicological sciences : an official journal of the Society of Toxicology 20040801
Inflammatory mediator and beta-amyloid (25-35)-induced ceramide generation and iNOS expression are inhibited by vitamin E. Free radical biology & medicine 20040801
Determination of fumonisins B1 and B2 in herbal tea and medicinal plants in Turkey by high-performance liquid chromatography. Journal of food protection 20040801
Toxicity of maize containing known levels of fumonisin B1 during force-feeding of ducks. Poultry science 20040801
Lipid rafts mediate the synaptic localization of alpha-synuclein. The Journal of neuroscience : the official journal of the Society for Neuroscience 20040728
Disruption of sphingolipid biosynthesis in hepatocyte nodules: selective proliferative stimulus induced by fumonisin B1. Toxicology 20040715
Fumonisin B1-induced hepatocellular and cholangiocellular tumors in male Fischer 344 rats: potentiating effects of 2-acetylaminofluorene on oval cell proliferation and neoplastic development in a discontinued feeding study. Carcinogenesis 20040701
Quantitative analysis of Fusarium mycotoxins in maize using accelerated solvent extraction before liquid chromatography/atmospheric pressure chemical ionization tandem mass spectrometry. Food additives and contaminants 20040701
Fumonisins in Brazilian corn-based foods for infant consumption. Food additives and contaminants 20040701
Production of fumonisins by Fusarium verticillioides strains on solid and in a defined liquid medium--effects of L-methionine and inoculum. Mycopathologia 20040701
The mycotoxin fumonisin B1 transiently activates nuclear factor-kappaB, tumor necrosis factor alpha and caspase 3 via protein kinase Calpha-dependent pathway in porcine renal epithelial cells. Cell biology and toxicology 20040701
Efficacy of a commercial mycotoxin binder in alleviating effects of ochratoxin A, fumonisin B1, moniliformin and zearalenone in adult mink. Veterinary and human toxicology 20040601
Ceramide synthesis correlates with the posttranscriptional regulation of the sterol-regulatory element-binding protein. Arteriosclerosis, thrombosis, and vascular biology 20040501
Determination of the mycotoxin fumonisin B1 in maize by reversed-phase thin-layer chromatography: a collaborative study. Food additives and contaminants 20040501
Lipid rafts and integrin activation regulate oligodendrocyte survival. The Journal of neuroscience : the official journal of the Society for Neuroscience 20040414
Involvement of c-Fos in fenretinide-induced apoptosis in human ovarian carcinoma cells. Cell death and differentiation 20040301
Selective and transient activation of protein kinase C alpha by fumonisin B1, a ceramide synthase inhibitor mycotoxin, in cultured porcine renal cells. Life sciences 20040206
Involvement of ceramide in hyperosmotic shock-induced death of erythrocytes. Cell death and differentiation 20040201
Toxicity and apoptosis induced by the mycotoxins nivalenol, deoxynivalenol and fumonisin B1 in a human erythroleukemia cell line. Toxicology in vitro : an international journal published in association with BIBRA 20040201
Mycotic keratitis: profile of Fusarium species and their mycotoxins. Mycoses 20040201
Liquid chromatographic determination of fumonisins B1, B2, and B3 in corn silage. Journal of agricultural and food chemistry 20040128
The role of de novo ceramide synthesis in the mechanism of action of the tricyclic xanthate D609. Journal of lipid research 20040101
The mycotoxin fumonisin B1 alters the proliferation and the barrier function of porcine intestinal epithelial cells. Toxicological sciences : an official journal of the Society of Toxicology 20040101
Radiation-induced apoptosis of oligodendrocytes and its association with increased ceramide and down-regulated protein kinase B/Akt activity. International journal of radiation biology 20040101
Neurologic abnormalities and cerebrospinal fluid changes in horses administered fumonisin B1 intravenously. Journal of veterinary internal medicine 20040101
Cytotoxicity induced by nivalenol, deoxynivalenol, and fumonisin B1 in the SF-9 insect cell line. In vitro cellular & developmental biology. Animal 20040101
Inhibitory effect of cinnamon, clove, lemongrass, oregano and palmarose essential oils on growth and fumonisin B1 production by Fusarium proliferatum in maize grain. International journal of food microbiology 20031231
Sugars and amino acids as factors affecting the synthesis of fumonisins in liquid cultures by isolates of the Gibberella fujikuroi complex. International journal of food microbiology 20031231
Evaluation of conventional and organic italian foodstuffs for deoxynivalenol and fumonisins B(1) and B(2). Journal of agricultural and food chemistry 20031231
Sphingosine-1-phosphate in inhibition of male germ cell apoptosis in the human testis. The Journal of clinical endocrinology and metabolism 20031101
Comparison of fumonisin B1 biosynthesis in maize germ and degermed kernels by Fusarium verticillioides. Journal of food protection 20031101
Two mammalian longevity assurance gene (LAG1) family members, trh1 and trh4, regulate dihydroceramide synthesis using different fatty acyl-CoA donors. The Journal of biological chemistry 20031031
Fumonisin B1-induced apoptosis is associated with delayed inhibition of protein kinase C, nuclear factor-kappaB and tumor necrosis factor alpha in LLC-PK1 cells. Chemico-biological interactions 20031025
Toxicological effects of chronic low doses of aflatoxin B(1) and fumonisin B(1)-containing Fusarium moniliforme culture material in weaned piglets. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20031001
Effects of muffin processing on fumonisins from 14C-labeled toxins produced in cultured corn kernels. Journal of food protection 20031001
Selective lack of the C16:0 fatty acid isoform of sulfatide in pancreas of type II diabetic animal models. APMIS : acta pathologica, microbiologica, et immunologica Scandinavica 20030901
Bound fumonisin B1: analysis of fumonisin-B1 glyco and amino acid conjugates by liquid chromatography-electrospray ionization-tandem mass spectrometry. Journal of agricultural and food chemistry 20030827
Fumonisin contamination and fusarium incidence in corn from Santa Catarina, Brazil. Journal of agricultural and food chemistry 20030827
The reverse activity of human acid ceramidase. The Journal of biological chemistry 20030808
Occurrence of certain mycotoxins in corn and corn-based products and thermostability of fumonisin B1 during processing. Die Nahrung 20030801
Sphinganine to sphingosine ratio and predictive biochemical markers of fumonisin B1 exposure in ducks. Chemico-biological interactions 20030725
Elevation of de novo ceramide synthesis in tumor masses and the role of microsomal dihydroceramide synthase. International journal of cancer 20030520
Sphingoid bases and their phosphates: transient activation and delayed repression of protein kinase C isoforms and their possible involvement in fumonisin B1 cytotoxicity. Toxicology 20030503
Naturally occurring phenols: a detoxification strategy for fumonisin B1. Food additives and contaminants 20030501
Lipid rafts in the maintenance of synapses, dendritic spines, and surface AMPA receptor stability. The Journal of neuroscience : the official journal of the Society for Neuroscience 20030415
Mycoflora and fumonisin mycotoxins associated with cowpea [Vigna unguiculata (L.) Walp] seeds. Journal of agricultural and food chemistry 20030409
Inhibitors of glycosphingolipid biosynthesis reduce transepithelial electrical resistance in MDCK I and FRT cells. American journal of physiology. Cell physiology 20030401
De novo ceramide synthesis participates in the ultraviolet B irradiation-induced apoptosis in undifferentiated cultured human keratinocytes. The Journal of investigative dermatology 20030401
Monounsaturated fatty acids prevent the deleterious effects of palmitate and high glucose on human pancreatic beta-cell turnover and function. Diabetes 20030301
Comparative study of the toxic effects of fumonisin B1 in rat C6 glioma cells and p53-null mouse embryo fibroblasts. Toxicology 20030201
Hidden fumonisin in corn flakes. Food additives and contaminants 20030201
Enhanced phagocytosis through inhibition of de novo ceramide synthesis. The Journal of biological chemistry 20030110
Modulators of ceramide metabolism sensitize colorectal cancer cells to chemotherapy: a novel treatment strategy. Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract 20030101
Deletion of IFN-gamma reduces fumonisin-induced hepatotoxicity in mice via alterations in inflammatory cytokines and apoptotic factors. Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research 20030101
Screening toxicity study in young carp (Cyprinus carpio L.) on feed amended with fumonisin B1. Mycopathologia 20030101
Effect of dietary fumonisin B1 on certain immune parameters of weaned pigs. Acta veterinaria Hungarica 20030101
Individual and combined effects of the Fusarium mycotoxins fumonisin B1 and moniliformin in broiler chicks. Avian diseases 20030101
Comparison of the toxicity of several fumonisin derivatives in a 28-day feeding study with female B6C3F(1) mice. Toxicology and applied pharmacology 20021215
A lysophosphatidic acid analogue is revealed as a potent inhibitor of phosphatidylcholine synthesis, inducing apoptosis. The Biochemical journal 20021201
Acute activation of de novo sphingolipid biosynthesis upon heat shock causes an accumulation of ceramide and subsequent dephosphorylation of SR proteins. The Journal of biological chemistry 20021108
Prevention of fumonisin B1-induced neural tube defects by folic acid. Teratology 20021001
Fumonisin B1-induced localized activation of cytokine network in mouse liver. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20021001
Fumonisin B(1) alters sphingolipid metabolism and tumor necrosis factor alpha expression in heart and lung of mice. Life sciences 20020913
A role for the de novo sphingolipids in apoptosis of photosensitized cells. Experimental cell research 20020910
Lipids and delta6-desaturase activity alterations in rat liver microsomal membranes induced by fumonisin B1. Lipids 20020901
Aflatoxin and fumonisin contamination of commercial corn (Zea mays) hybrids in Mississippi. Journal of agricultural and food chemistry 20020828
Cytotoxicity of fumonisin B1, diethylnitrosamine, and catechol on the SNO esophageal cancer cell line. Environmental health perspectives 20020801
Evaluation of Fumonisin B(1) and its metabolites absorption and toxicity on intestinal cells line Caco-2. Toxicon : official journal of the International Society on Toxinology 20020801
Characterization of fumonisin B(1)-glucose reaction kinetics and products. Journal of agricultural and food chemistry 20020731
Fumonisin B1 affects viability and alters nitric oxide production of a murine macrophage cell line. International immunopharmacology 20020701
Mycoflora and fumonisin contamination in Brazilian corn from sowing to harvest. Journal of agricultural and food chemistry 20020619
Ceramide accumulation is independent of camptothecin-induced apoptosis in prostate cancer LNCaP cells. Biochemical and biophysical research communications 20020607
Extraction of fumonisins B1 and B2 from white rice flour and their stability in white rice flour, cornstarch, cornmeal, and glucose. Journal of agricultural and food chemistry 20020605
Persistence and reversibility of the elevation in free sphingoid bases induced by fumonisin inhibition of ceramide synthase. Toxicological sciences : an official journal of the Society of Toxicology 20020601
The lysosomal transport of prosaposin requires the conditional interaction of its highly conserved d domain with sphingomyelin. The Journal of biological chemistry 20020510
Analysis of fumonisin B(1) in Fusarium proliferatum-infected asparagus spears and garlic bulbs from Germany by liquid chromatography-electrospray ionization mass spectrometry. Journal of agricultural and food chemistry 20020508
Fumonisin B(1) is genotoxic in human derived hepatoma (HepG2) cells. Mutagenesis 20020501
Pharmacological antagonism of fumonisin B1 cytotoxicity in porcine renal epithelial cells (LLC-PK1): a model for reducing fumonisin-induced nephrotoxicity in vivo. Pharmacology & toxicology 20020501
Simultaneous quantitative analysis of sphingoid base 1-phosphates in biological samples by o-phthalaldehyde precolumn derivatization after dephosphorylation with alkaline phosphatase. Analytical biochemistry 20020415
De novo ceramide regulates the alternative splicing of caspase 9 and Bcl-x in A549 lung adenocarcinoma cells. Dependence on protein phosphatase-1. The Journal of biological chemistry 20020412
Cardiovascular changes associated with intravenous administration of fumonisin B1 in horses. American journal of veterinary research 20020401
DNA damage in astrocytes exposed to fumonisin B1. Neurochemical research 20020401
Effect of fumonisin B1 on structure and function of macrophage plasma membrane. Toxicology letters 20020328
Modulation of selected cell signaling genes in mouse liver by fumonisin B1. Chemico-biological interactions 20020320
Ceramide and sphingosine rapidly induce apoptosis of murine mast cells supported by interleukin-3 and stem cell factor. Experimental hematology 20020301
[Sphingolipid probe]. Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme 20020301
Interaction of fumonisin B(1) and aflatoxin B(1) in a short-term carcinogenesis model in rat liver. Toxicology 20020227
N-(1-deoxy-D-fructos-1-yl) fumonisin B(1), the initial reaction product of fumonisin B(1) and D-glucose. Journal of agricultural and food chemistry 20020227
Fungal growth and fusarium mycotoxin content in isogenic traditional maize and genetically modified maize grown in France and Spain. Journal of agricultural and food chemistry 20020213
Palmitate-induced cardiac apoptosis is mediated through CPT-1 but not influenced by glucose and insulin. American journal of physiology. Heart and circulatory physiology 20020201
Toxicity of fumonisin from Fusarium verticillioides culture material and moniliformin from Fusarium fujikuroi culture material when fed singly and in combination to growing barrows. Journal of food protection 20020201
Cytotoxic and genotoxic effects of fumonisin B1 on rabbit kidney RK13 cell line. Archives of toxicology 20020201
Temporal expression of fumonisin B(1)-induced tumor necrosis factor-alpha and interferon gamma in mice. Comparative biochemistry and physiology. Toxicology & pharmacology : CBP 20020201
pH-dependent interaction of fumonisin B1 with cholesterol: physicochemical and molecular modeling studies at the air-water interface. Journal of agricultural and food chemistry 20020116
Role of diacylglycerol in PKD recruitment to the TGN and protein transport to the plasma membrane. Science (New York, N.Y.) 20020111
DNA damage in human fibroblasts exposed to fumonisin B(1). Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20020101
Chronic effects of fumonisin B1 in broilers and turkeys fed dietary treatments to market age. Poultry science 20020101
Determination of total fumonisins in corn by competitive direct enzyme-linked immunosorbent assay: collaborative study. Journal of AOAC International 20020101
In vivo and in vitro electrophysiological monitoring of rat neocortical activity after dietary fumonisin exposure. Mycopathologia 20020101
Carcinogenicity and mechanism of action of fumonisin B1: a mycotoxin produced by Fusarium moniliforme (= F. verticillioides). Cancer detection and prevention 20020101
Accumulation of fumonisins B1 and B2 in freshly harvested Brazilian commercial maize at three locations during two nonconsecutive seasons. Mycopathologia 20020101
Survey of Fusarium moniliforme (F. verticillioides) and production of fumonisin B1 in cereal grains and oilseeds in Zimbabwe. International journal of food microbiology 20011230
Toxicology and carcinogenesis studies of fumonisin B1 (cas no. 116355-83-0) in F344/N rats and B6C3F1 mice (feed studies). National Toxicology Program technical report series 20011201
FAS activation induces dephosphorylation of SR proteins; dependence on the de novo generation of ceramide and activation of protein phosphatase 1. The Journal of biological chemistry 20011130
Co-occurrence of aflatoxins B1, B2, G1, G2, zearalenone and fumonisin B1 in Brazilian corn. Food additives and contaminants 20011101
Sphingolipids as biomarkers of fumonisin exposure and risk of esophageal squamous cell carcinoma in china. Cancer causes & control : CCC 20011101
[Survey on the fumonisins intake and the urinary Sa/So ratio of people suffered from a high incidence of esophageal cancer]. Wei sheng yan jiu = Journal of hygiene research 20011101
Fumonisin B(1) induces apoptosis in LLC-PK(1) renal epithelial cells via a sphinganine- and calmodulin-dependent pathway. Toxicology and applied pharmacology 20011015
Sphingomyelinase but not ceramide induces nitric oxide synthase expression in rat brain microglia. Neuroscience letters 20010928
Fusarium species (section Liseola) and its mycotoxins in maize harvested in northern Argentina. Food additives and contaminants 20010901
The induction and persistence of altered sphingolipid biosynthesis in rats treated with fumonisin B1. Food additives and contaminants 20010901
Cancer initiation by fumonisin B(1) in rat liver--role of cell proliferation. Cancer letters 20010828
Gender-related differences in subacute fumonisin B1 hepatotoxicity in BALB/c mice. Toxicology 20010828
Evaluation of fumonisin-aflatoxin co-occurrence in Brazilian corn hybrids by ELISA. Food additives and contaminants 20010801
Fumonisins B1 and B2 in black tea and medicinal plants. Journal of food protection 20010801
Reaction of fumonisin with glucose prevents promotion of hepatocarcinogenesis in female F344/N rats while maintaining normal hepatic sphinganine/sphingosine ratios. Journal of agricultural and food chemistry 20010801
Aflatoxins and fumonisins in corn from the high-incidence area for human hepatocellular carcinoma in Guangxi, China. Journal of agricultural and food chemistry 20010801
Fumonisin B1 metabolism by bovine liver microsomes. Veterinary research communications 20010801
The effect of repeated gavage doses of fumonisin B1 on the sphinganine and sphingosine levels in vervet monkeys. Toxicon : official journal of the International Society on Toxinology 20010701
Fumonisin-induced tumor necrosis factor-alpha expression in a porcine kidney cell line is independent of sphingoid base accumulation induced by ceramide synthase inhibition. Toxicology and applied pharmacology 20010701
Generation of ceramide in murine macrophages infected with Leishmania donovani alters macrophage signaling events and aids intracellular parasitic survival. Molecular and cellular biochemistry 20010701
Experimental subchronic mycotoxicoses in mice: individual and combined effects of dietary exposure to fumonisins and aflatoxin B1. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20010601
Combined synthetic/CD strategy for the stereochemical assignment of the tricarballylic acid side chains of fumonisin B(1). The Journal of organic chemistry 20010601
Toxicity of Fusarium moniliforme culture material containing known levels of fumonisin B1 in ducks. Toxicology 20010528
Effects of fumonisin B1 present in Fusarium moniliforme culture material on drug metabolising enzyme activities in ducks. Toxicology letters 20010519
Biochemical characterization of the reverse activity of rat brain ceramidase. A CoA-independent and fumonisin B1-insensitive ceramide synthase. The Journal of biological chemistry 20010518
Effect of processing on fumonisin concentration in corn flakes. Journal of food protection 20010501
Proceedings of the International Conference on the Toxicology of Fumonisin. 28-30 June 1999, Arlington, Virginia. Environmental health perspectives 20010501
Discovery and occurrence of the fumonisins: a historical perspective. Environmental health perspectives 20010501
Fumonisin toxicosis in swine: an overview of porcine pulmonary edema and current perspectives. Environmental health perspectives 20010501
An overview of rodent toxicities: liver and kidney effects of fumonisins and Fusarium moniliforme. Environmental health perspectives 20010501
Toxicity of culture material of Fusarium verticillioides strain MRC 826 to nonhuman primates. Environmental health perspectives 20010501
Fumonisin b1 carcinogenicity in a two-year feeding study using F344 rats and B6C3F1 mice. Environmental health perspectives 20010501
Sphingolipid metabolism: roles in signal transduction and disruption by fumonisins. Environmental health perspectives 20010501
Fumonisin-induced hepatocarcinogenesis: mechanisms related to cancer initiation and promotion. Environmental health perspectives 20010501
Sphingolipid perturbations as mechanisms for fumonisin carcinogenesis. Environmental health perspectives 20010501
Analysis of fumonisin B1-induced apoptosis. Environmental health perspectives 20010501
Factors that affect the occurrence of fumonisin. Environmental health perspectives 20010501
Biological control of Fusarium moniliforme in maize. Environmental health perspectives 20010501
Control of fumonisin: effects of processing. Environmental health perspectives 20010501
Prospects for reducing fumonisin contamination of maize through genetic modification. Environmental health perspectives 20010501
Determination of N-(carboxymethyl)fumonisin B(1) in corn products by liquid chromatography/electrospray ionization--mass spectrometry. Journal of agricultural and food chemistry 20010501
Efficacy of ammonia in detoxification of fumonisin contaminated corn. Indian journal of experimental biology 20010501
Regulated apical secretion of zymogens in rat pancreas. Involvement of the glycosylphosphatidylinositol-anchored glycoprotein GP-2, the lectin ZG16p, and cholesterol-glycosphingolipid-enriched microdomains. The Journal of biological chemistry 20010427
Induction of apoptosis through B-cell receptor cross-linking occurs via de novo generated C16-ceramide and involves mitochondria. The Journal of biological chemistry 20010427
Daunorubicin attenuates tumor necrosis factor-alpha-induced biosynthesis of plasminogen activator inhibitor-1 in human umbilical vein endothelial cells. Biochimica et biophysica acta 20010423
Occurrence of fumonisin B1 in maize imported into Taiwan. International journal of food microbiology 20010411
Fumonisin B(1) increases serum sphinganine concentration but does not alter serum sphingosine concentration or induce cardiovascular changes in milk-fed calves. Toxicological sciences : an official journal of the Society of Toxicology 20010401
Fumonisin B(1) is hepatotoxic and nephrotoxic in milk-fed calves. Toxicological sciences : an official journal of the Society of Toxicology 20010401
Fumonisin B1 promotes aflatoxin B1 and N-methyl-N'-nitro-nitrosoguanidine-initiated liver tumors in rainbow trout. Toxicology and applied pharmacology 20010401
The toxicity of fumonisin B1, B2, and B3, individually and in combination, in chicken embryos. Poultry science 20010401
Differential effects of fumonisin B1 on cell death in cultured cells: the significance of the elevated sphinganine. Archives of pharmacal research 20010401
Toxicological effects in rats chronically fed low dietary levels of fumonisin B(1). Toxicology 20010321
De novo synthesis and recycling pathways of sphingomyelin in rat Sertoli cells. Biochemical and biophysical research communications 20010309
Preliminary evaluation of fumonisins by the Nordic countries and occurrence of fumonisins (FB1 and FB2) in corn-based foods on the Danish market. Food additives and contaminants 20010301
A mechanistic approach to modelling the risk of liver tumours in mice exposed to fumonisin B1 in the diet. Food additives and contaminants 20010301
Tissue sphinganine as a biomarker of fumonisin-induced apoptosis. Food additives and contaminants 20010301
Determination of sphinganine, sphingosine and Sa/So ratio in urine of humans exposed to dietary fumonisin B1. Food additives and contaminants 20010301
Decreased fumonisin hepatotoxicity in mice with a targeted deletion of tumor necrosis factor receptor 1. Toxicology 20010221
Fluorescence polarization as a means for determination of fumonisins in maize. Journal of agricultural and food chemistry 20010201
The effect of a single gavage dose of fumonisin B(1) on the sphinganine and sphingosine levels in vervet monkeys. Toxicon : official journal of the International Society on Toxinology 20010101
Preparatory isolation of mycotoxins from solid phase fungal cultures. Methods in molecular biology (Clifton, N.J.) 20010101
Identification of differentially expressed genes following treatment of monkey kidney cells with the mycotoxin fumonisin B(1). Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20010101
Ceramide generation occurring during 7beta-hydroxycholesterol- and 7-ketocholesterol-induced apoptosis is caspase independent and is not required to trigger cell death. Cell death and differentiation 20010101
FADD null mouse embryonic fibroblasts undergo apoptosis after photosensitization with the silicon phthalocyanine Pc 4. Archives of biochemistry and biophysics 20010101
Effects of prolonged oral administration of fumonisin B1 and aflatoxin B1 in rats. Mycopathologia 20010101
Effect of Fusarium, Paecilomyces and Trichoderma formulations against aphid Schizaphis graminum. Mycopathologia 20010101
In vitro and in vivo studies to assess the effectiveness of cholestyramine as a binding agent for fumonisins. Mycopathologia 20010101
Involvement of sphingosine in mitochondria-dependent Fas-induced apoptosis of type II Jurkat T cells. The Journal of biological chemistry 20000526
Nitric oxide inhibits tumor necrosis factor-alpha-induced apoptosis by reducing the generation of ceramide. Proceedings of the National Academy of Sciences of the United States of America 20000509
Ceramide accumulation precedes caspase-dependent apoptosis in CHP-100 neuroepithelioma cells exposed to the protein phosphatase inhibitor okadaic acid. Cell death and differentiation 19990701
Ataxia telangiectasia-mutated gene product inhibits DNA damage-induced apoptosis via ceramide synthase. The Journal of biological chemistry 19990618
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