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Home > Pyridines > 1161205-04-4
1161205-04-4 | 2-Pyridinecarboxamide, N-(4-chloro-3-methoxyphenyl)-
CAS No: 1161205-04-4 Catalog No: AG000BOL MDL No:MFCD16618402
Product Description
Catalog Number:
AG000BOL
Chemical Name:
2-Pyridinecarboxamide, N-(4-chloro-3-methoxyphenyl)-
CAS Number:
1161205-04-4
Molecular Formula:
C13H11ClN2O2
Molecular Weight:
262.6916
MDL Number:
MFCD16618402
IUPAC Name:
N-(4-chloro-3-methoxyphenyl)pyridine-2-carboxamide
InChI:
InChI=1S/C13H11ClN2O2/c1-18-12-8-9(5-6-10(12)14)16-13(17)11-4-2-3-7-15-11/h2-8H,1H3,(H,16,17)
InChI Key:
ARYUXFNGXHNNDM-UHFFFAOYSA-N
SMILES:
COc1cc(ccc1Cl)NC(=O)c1ccccn1
Properties
Complexity:
288
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
1
Defined Atom Stereocenter Count:
0
Defined Bond Stereocenter Count:
0
Exact Mass:
262.051g/mol
Formal Charge:
0
Heavy Atom Count:
18
Hydrogen Bond Acceptor Count:
3
Hydrogen Bond Donor Count:
1
Isotope Atom Count:
0
Molecular Weight:
262.693g/mol
Monoisotopic Mass:
262.051g/mol
Rotatable Bond Count:
3
Topological Polar Surface Area:
51.2A^2
Undefined Atom Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
XLogP3:
2.6
Literature
| Title | Journal |
|---|---|
| Functional and pharmacological characteristics of metabotropic glutamate receptors 2/4 heterodimers. | Molecular pharmacology 20120901 |
| Discovery, synthesis, and structure-activity relationship development of a series of N-4-(2,5-dioxopyrrolidin-1-yl)phenylpicolinamides (VU0400195, ML182): characterization of a novel positive allosteric modulator of the metabotropic glutamate receptor 4 (mGlu(4)) with oral efficacy in an antiparkinsonian animal model. | Journal of medicinal chemistry 20111110 |
| Tricyclic thiazolopyrazole derivatives as metabotropic glutamate receptor 4 positive allosteric modulators. | Journal of medicinal chemistry 20110728 |
| Discovery, synthesis, and structure-activity relationship development of a series of N-(4-acetamido)phenylpicolinamides as positive allosteric modulators of metabotropic glutamate receptor 4 (mGlu(4)) with CNS exposure in rats. | Journal of medicinal chemistry 20110224 |
| Synthesis and evaluation of a series of heterobiarylamides that are centrally penetrant metabotropic glutamate receptor 4 (mGluR4) positive allosteric modulators (PAMs). | Journal of medicinal chemistry 20090723 |
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