200,000+ products from a single source!
sales@angenechem.com
114873-37-9 | 1,4,7,10-Tetraazacyclododecane-1,4,7-triacetic acid
CAS No: 114873-37-9 Catalog No: AG000FDN MDL No:
Product Description
Catalog Number:
AG000FDN
Chemical Name:
1,4,7,10-Tetraazacyclododecane-1,4,7-triacetic acid
CAS Number:
114873-37-9
Molecular Formula:
C14H26N4O6
Molecular Weight:
346.3794
IUPAC Name:
2-[4,7-bis(carboxymethyl)-1,4,7,10-tetrazacyclododec-1-yl]acetic acid
InChI:
InChI=1S/C14H26N4O6/c19-12(20)9-16-3-1-15-2-4-17(10-13(21)22)6-8-18(7-5-16)11-14(23)24/h15H,1-11H2,(H,19,20)(H,21,22)(H,23,24)
InChI Key:
HHLZCENAOIROSL-UHFFFAOYSA-N
SMILES:
OC(=O)CN1CCN(CCNCCN(CC1)CC(=O)O)CC(=O)O
Properties
Complexity:
404
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
1
Defined Atom Stereocenter Count:
0
Defined Bond Stereocenter Count:
0
Exact Mass:
346.185g/mol
Formal Charge:
0
Heavy Atom Count:
24
Hydrogen Bond Acceptor Count:
10
Hydrogen Bond Donor Count:
4
Isotope Atom Count:
0
Molecular Weight:
346.384g/mol
Monoisotopic Mass:
346.185g/mol
Rotatable Bond Count:
6
Topological Polar Surface Area:
134A^2
Undefined Atom Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
XLogP3:
-8.4
Literature
| Title | Journal |
|---|---|
| 177Lu-DO3A-HSA-Z EGFR:1907: characterization as a potential radiopharmaceutical for radionuclide therapy of EGFR-expressing head and neck carcinomas. | Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry 20120601 |
| Evaluation of (111)In-labeled macrocyclic chelator-amino acid derivatives for cancer imaging. | Nuclear medicine and biology 20120401 |
| Measuring in vivo tumor pHe with CEST-FISP MRI. | Magnetic resonance in medicine 20120301 |
| Dual-functional gadolinium-based copper(II) probe for selective magnetic resonance imaging and fluorescence sensing. | Inorganic chemistry 20120220 |
| Improved pH measurements with a single PARACEST MRI contrast agent. | Contrast media & molecular imaging 20120101 |
| Reversible low-light induced photoswitching of crowned spiropyran-DO3A complexed with gadolinium(III) ions. | Molecules (Basel, Switzerland) 20120101 |
| Tumor targeting using anti-epidermal growth factor receptor (ior egf/r3) immunoconjugate with a tetraaza macrocyclic agent (DO3A-EA). | Molecular imaging 20120101 |
| Effects of terbium chelate structure on dipicolinate ligation and the detection of Bacillus spores. | Journal of inorganic biochemistry 20111201 |
| Radiolabeling of PAMAM dendrimers conjugated to a pyridine-N-oxide DOTA analog with ¹¹¹In: Optimization of reaction conditions and biodistribution. | Journal of pharmaceutical and biomedical analysis 20111101 |
| Structure-related variable responses of calcium sensitive MRI probes. | Organic & biomolecular chemistry 20110821 |
| LDL-based nanoparticles for contrast enhanced MRI of atheroplaques in mouse models. | Chemical communications (Cambridge, England) 20110821 |
| Synthesis and radiolabeling of chelator-RNA aptamer bioconjugates with copper-64 for targeted molecular imaging. | Bioorganic & medicinal chemistry 20110701 |
| In vitro imaging and human serum albumin responsive dimeric lanthanide DO3A complex. | Inorganic chemistry 20110620 |
| Comparison of the in vivo distribution of four different annexin a5 adducts in rhesus monkeys. | International journal of molecular imaging 20110101 |
| In vitro and in vivo evaluation of ⁶⁴Cu-radiolabeled KCCYSL peptides for targeting epidermal growth factor receptor-2 in breast carcinomas. | Cancer biotherapy & radiopharmaceuticals 20101201 |
| Synthesis of novel 68Ga-labeled amino acid derivatives for positron emission tomography of cancer cells. | Nuclear medicine and biology 20101101 |
| Design, synthesis, and evaluation of 1,4,7,10-tetraazacyclododecane-1,4,7-triacetic acid derived, redox-sensitive contrast agents for magnetic resonance imaging. | Journal of medicinal chemistry 20100923 |
| Molecular recognition of sialic acid by lanthanide(III) complexes through cooperative two-site binding. | Inorganic chemistry 20100503 |
| An osteoclast-targeting agent for imaging and therapy of bone metastasis. | Bioorganic & medicinal chemistry letters 20080901 |
| Evaluation of maleimide derivative of DOTA for site-specific labeling of recombinant affibody molecules. | Bioconjugate chemistry 20080101 |
| Design and characterization of a new irreversible responsive PARACEST MRI contrast agent that detects nitric oxide. | Magnetic resonance in medicine 20071201 |
| Sensitization of europium(III) luminescence by benzophenone-containing ligands: regioisomers, rearrangements and chelate ring size, and their influence on quantum yields. | Inorganic chemistry 20071029 |
| Radiohybridization PET imaging of KRAS G12D mRNA expression in human pancreas cancer xenografts with [(64)Cu]DO3A-peptide nucleic acid-peptide nanoparticles. | Cancer biology & therapy 20070601 |
| RGD targeted poly(L-glutamic acid)-cystamine-(Gd-DO3A) conjugate for detecting angiogenesis biomarker alpha(v) beta3 integrin with MRT, mapping. | International journal of nanomedicine 20070601 |
| Indium-labeled macrocyclic conjugates of naltrindole: high-affinity radioligands for in vivo studies of peripheral delta opioid receptors. | Journal of medicinal chemistry 20070503 |
| Fluorescence-based affinity labeling of nucleobase by hydrogen-bond forming metal complex. | Nucleic acids symposium series (2004) 20070101 |
| Unexpected aggregation of neutral, xylene-cored dinuclear GdIII chelates in aqueous solution. | Chemistry (Weinheim an der Bergstrasse, Germany) 20060906 |
| Local targeting of malignant gliomas by the diffusible peptidic vector 1,4,7,10-tetraazacyclododecane-1-glutaric acid-4,7,10-triacetic acid-substance p. | Clinical cancer research : an official journal of the American Association for Cancer Research 20060615 |
| A potential Dubin-Johnson syndrome imaging agent: synthesis, biodistribution, and microPET imaging. | Molecular imaging 20050101 |
| New lanthanide complexes for sensitized visible and near-IR light emission: synthesis, 1H NMR, and X-ray structural investigation and photophysical properties. | Inorganic chemistry 20040223 |
| NMR relaxometric study of new Gd(III) macrocyclic complexes and their interaction with human serum albumin. | Organic & biomolecular chemistry 20040221 |
| Highly luminescent Eu(3+) and Tb(3+) macrocyclic complexes bearing an appended phenanthroline chromophore. | Inorganic chemistry 20020520 |
| Chelators for radioimmunotherapy: I. NMR and ab initio calculation studies on 1,4,7,10-tetra(carboxyethyl)-1,4,7,10-tetraazacyclododecane (DO4Pr) and 1,4,7-tris(carboxymethyl)-10-(carboxyethyl)-1,4,7,10-tetraazacyclododecane (DO3A1Pr). | Inorganic chemistry 20010813 |
| Inulin as a carrier for contrast agents in magnetic resonance imaging. | Chemistry (Weinheim an der Bergstrasse, Germany) 20010105 |
Related Products
Featured Products
© 2019 Angene International Limited. All rights Reserved.