200,000+ products from a single source!
sales@angenechem.com
114753-52-5 | Adenosine, 2-amino-3'-azido-2',3'-dideoxy-
CAS No: 114753-52-5 Catalog No: AG000F6K MDL No:
Product Description
Catalog Number:
AG000F6K
Chemical Name:
Adenosine, 2-amino-3'-azido-2',3'-dideoxy-
CAS Number:
114753-52-5
Molecular Formula:
C10H13N9O2
Molecular Weight:
291.2693
IUPAC Name:
[(2S,3S,5R)-3-azido-5-(2,6-diaminopurin-9-yl)oxolan-2-yl]methanol
InChI:
InChI=1S/C10H13N9O2/c11-8-7-9(16-10(12)15-8)19(3-14-7)6-1-4(17-18-13)5(2-20)21-6/h3-6,20H,1-2H2,(H4,11,12,15,16)/t4-,5+,6+/m0/s1
InChI Key:
BFTAFRDMRHNFKO-KVQBGUIXSA-N
SMILES:
[N-]=[N+]=N[C@H]1C[C@@H](O[C@@H]1CO)n1cnc2c1nc(N)nc2N
Properties
Complexity:
431
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
1
Defined Atom Stereocenter Count:
3
Defined Bond Stereocenter Count:
0
Exact Mass:
291.119g/mol
Formal Charge:
0
Heavy Atom Count:
21
Hydrogen Bond Acceptor Count:
9
Hydrogen Bond Donor Count:
3
Isotope Atom Count:
0
Molecular Weight:
291.275g/mol
Monoisotopic Mass:
291.119g/mol
Rotatable Bond Count:
3
Topological Polar Surface Area:
140A^2
Undefined Atom Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
XLogP3:
0
Literature
| Title | Journal |
|---|---|
| Substrate mimicry: HIV-1 reverse transcriptase recognizes 6-modified-3'-azido-2',3'-dideoxyguanosine-5'-triphosphates as adenosine analogs. | Nucleic acids research 20120101 |
| Synthesis, antiviral activity, cytotoxicity and cellular pharmacology of l-3'-azido-2',3'-dideoxypurine nucleosides. | European journal of medicinal chemistry 20110901 |
| Synthesis and evaluation of 3'-azido-2',3'-dideoxypurine nucleosides as inhibitors of human immunodeficiency virus. | Bioorganic & medicinal chemistry letters 20100101 |
| Telomere shortening in human HL60 cells by treatment with 3'-azido-2',3'-dideoxynucleosides and telomerase inhibition by their 5'-triphosphates. | Nucleosides, nucleotides & nucleic acids 20070101 |
| Nucleic acid related compounds. 57. Synthesis, x-ray crystal structure, lipophilic partition properties, and antiretroviral activities of anomeric 3'-azido-2',3'-dideoxy-2,6-diaminopurine ribosides. | Journal of medicinal chemistry 19890801 |
| Potentiating effect of ribavirin on the anti-retrovirus activity of 3'-azido-2,6-diaminopurine-2',3'-dideoxyriboside in vitro and in vivo. | Antiviral research 19890101 |
| Potent and selective activity of 3'-azido-2,6-diaminopurine-2',3'-dideoxyriboside, 3'-fluoro-2,6-diaminopurine-2',3'-dideoxyriboside, and 3'-fluoro-2',3'-dideoxyguanosine against human immunodeficiency virus. | Molecular pharmacology 19880301 |
Related Products
Featured Products
© 2019 Angene International Limited. All rights Reserved.