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112648-68-7

112648-68-7 | 1-[6-[[(17β)-3-Methoxyestra-1,3,5(10)-trien-17-yl]amino]hexyl]-1H-pyrrole-2,5-dione

CAS No: 112648-68-7 Catalog No: AG00387S MDL No:MFCD00893825

Product Description

Catalog Number:
AG00387S
Chemical Name:
1-[6-[[(17β)-3-Methoxyestra-1,3,5(10)-trien-17-yl]amino]hexyl]-1H-pyrrole-2,5-dione
CAS Number:
112648-68-7
Molecular Formula:
C29H40N2O3
Molecular Weight:
464.6395
MDL Number:
MFCD00893825
IUPAC Name:
1-[6-[[(8R,9S,13S,14S,17S)-3-methoxy-13-methyl-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthren-17-yl]amino]hexyl]pyrrole-2,5-dione
InChI:
InChI=1S/C29H40N2O3/c1-29-16-15-23-22-10-8-21(34-2)19-20(22)7-9-24(23)25(29)11-12-26(29)30-17-5-3-4-6-18-31-27(32)13-14-28(31)33/h8,10,13-14,19,23-26,30H,3-7,9,11-12,15-18H2,1-2H3/t23-,24-,25+,26+,29+/m1/s1
InChI Key:
LUFAORPFSVMJIW-ZRJUGLEFSA-N
SMILES:
COc1ccc2c(c1)CC[C@@H]1[C@@H]2CC[C@]2([C@H]1CC[C@@H]2NCCCCCCN1C(=O)C=CC1=O)C

Properties

Complexity:
763  
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
5  
Defined Bond Stereocenter Count:
0
Exact Mass:
464.304g/mol
Formal Charge:
0
Heavy Atom Count:
34  
Hydrogen Bond Acceptor Count:
4  
Hydrogen Bond Donor Count:
1  
Isotope Atom Count:
0
Molecular Weight:
464.65g/mol
Monoisotopic Mass:
464.304g/mol
Rotatable Bond Count:
9  
Topological Polar Surface Area:
58.6A^2
Undefined Atom Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
XLogP3:
4  

Literature

Title Journal
Effects of Neonicotinoid Pesticides on Promoter-Specific Aromatase (CYP19) Expression in Hs578t Breast Cancer Cells and the Role of the VEGF Pathway. Environmental health perspectives 20180401
Deoxynivalenol (Vomitoxin)-Induced Cholecystokinin and Glucagon-Like Peptide-1 Release in the STC-1 Enteroendocrine Cell Model Is Mediated by Calcium-Sensing Receptor and Transient Receptor Potential Ankyrin-1 Channel. Toxicological sciences : an official journal of the Society of Toxicology 20150601
Dibutyltin promotes oxidative stress and increases inflammatory mediators in BV-2 microglia cells. Toxicology letters 20141015
The mechanism of honokiol-induced intracellular Ca(2+) rises and apoptosis in human glioblastoma cells. Chemico-biological interactions 20140925
Interaction between bradykinin and natriuretic peptides via RGS protein activation in HEK-293 cells. American journal of physiology. Cell physiology 20121215
Involvement of presynaptic voltage-dependent Kv3 channel in endothelin-1-induced inhibition of noradrenaline release from rat gastric sympathetic nerves. European journal of pharmacology 20121105
PYK-2 is tyrosine phosphorylated after activation of pituitary adenylate cyclase activating polypeptide receptors in lung cancer cells. Journal of molecular neuroscience : MN 20121101
Role of Ca2+ in proteolysis-inducing factor (PIF)-induced atrophy of skeletal muscle. Cellular signalling 20121101
Activation of transmembrane bile acid receptor TGR5 stimulates insulin secretion in pancreatic β cells. Biochemical and biophysical research communications 20121026
Effect of methoxychlor on Ca(2+) movement and viability in MDCK renal tubular cells. Basic & clinical pharmacology & toxicology 20121001
Involvement of phospholipase C-γ in the pro-survival role of glial cell line-derived neurotrophic factor in developing motoneurons in rat spinal cords. Molecular medicine reports 20121001
Regulation of estradiol and progesterone production by CRH-R1 and -R2 is through divergent signaling pathways in cultured human placental trophoblasts. Endocrinology 20121001
Brain phospholipase C, diacylglycerol lipase and monoacylglycerol lipase are involved in (±)-epibatidine-induced activation of central adrenomedullary outflow in rats. European journal of pharmacology 20120915
Facilitation of sympathetic neurotransmission by phosphatidylinositol-4,5-bisphosphate-dependent regulation of KCNQ channels in rat mesenteric arteries. Hypertension research : official journal of the Japanese Society of Hypertension 20120901
The non-genomic rapid acidification in peripheral T cells by progesterone depends on intracellular calcium increase and not on Na+/H+-exchange inhibition. Steroids 20120801
IP3-mediated octopamine-induced synaptic enhancement of crayfish LG neurons. Journal of comparative physiology. A, Neuroethology, sensory, neural, and behavioral physiology 20120801
Implication of multiple signaling pathways in the regulation of angiotensin II induced enhanced expression of Giα proteins in vascular smooth muscle cells. Canadian journal of physiology and pharmacology 20120801
P2Y receptors regulate proliferation of human pancreatic duct epithelial cells. Pancreas 20120701
Stratum oriens stimulation-evoked modulation of hippocampal long-term potentiation involves the activation of muscarinic acetylcholine receptors and the inhibition of Kv7/M potassium ion channels. The European journal of neuroscience 20120701
Phospholipase C mediates cadmium-dependent apoptosis in HEK 293 cells. Basic & clinical pharmacology & toxicology 20120601
Regulation of hippocampal long-term potentiation and long-term depression by diacylglycerol kinase ζ. Hippocampus 20120501
Activation of phospholipase-Cγ and protein kinase C signal pathways helps the survival of spinal motoneurons injured by root avulsion. Journal of neurochemistry 20120501
Arsenite promotes apoptosis and dysfunction in microvascular endothelial cells via an alteration of intracellular calcium homeostasis. Toxicology in vitro : an international journal published in association with BIBRA 20120401
Activation of neuronal P2X7 receptor-pannexin-1 mediates death of enteric neurons during colitis. Nature medicine 20120401
Gymnopilin--a substance produced by the hallucinogenic mushroom, Gymnopilus junonius--mobilizes intracellular Ca(2+) in dorsal root ganglion cells. Biomedical research (Tokyo, Japan) 20120401
Thiopental-induced insulin secretion via activation of IP3-sensitive calcium stores in rat pancreatic β-cells. American journal of physiology. Cell physiology 20120301
Effect of m-3m3FBS on Ca2+ handling and viability in OC2 human oral cancer cells. Acta physiologica Hungarica 20120301
Transient Ca2+ mobilization caused by osmotic shock initiates salmonid fish sperm motility. The Journal of experimental biology 20120215
CCL3 induced migration occurs independently of intracellular calcium release. Biochemical and biophysical research communications 20120203
The dopamine D(2) receptor is expressed and sensitizes adenylyl cyclase activity in airway smooth muscle. American journal of physiology. Lung cellular and molecular physiology 20120201
Stimulation of Ca2+-sensing receptor inhibits the basolateral 50-pS K channels in the thick ascending limb of rat kidney. Biochimica et biophysica acta 20120201
Inhibition of 5-lipoxygenase by U73122 is due to covalent binding to cysteine 416. Biochimica et biophysica acta 20120201
Diospyrin derivative, an anticancer quinonoid, regulates apoptosis at endoplasmic reticulum as well as mitochondria by modulating cytosolic calcium in human breast carcinoma cells. Biochemical and biophysical research communications 20120113
Non-classic androgen actions in Sertoli cell membrane in whole seminiferous tubules: effects of nandrolone decanoate and catechin. Steroids 20120101
Phospholipases C and D modulate proline accumulation in Thellungiella halophila/salsuginea differently according to the severity of salt or hyperosmotic stress. Plant & cell physiology 20120101
Ginsenoside Rg1 attenuates lipopolysaccharide-induced inflammatory responses via the phospholipase C-γ1 signaling pathway in murine BV-2 microglial cells. Current medicinal chemistry 20120101
Akt and phospholipase Cγ are involved in the regulation of growth and migration of MDA-MB-468 breast cancer and SW480 colon cancer cells when cultured with diabetogenic levels of glucose and insulin. BMC research notes 20120101
Neuromedin S increases L-type Ca(2+) channel currents through G(i)α-protein and phospholipase C-dependent novel protein kinase C delta pathway in adult rat ventricular myocytes. Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 20120101
Ionotropic glutamate receptor (iGluR)-like channels mediate MAMP-induced calcium influx in Arabidopsis thaliana. The Biochemical journal 20111215
ApoA-I enhances generation of HDL-like lipoproteins through interaction between ABCA1 and phospholipase Cγ in rat astrocytes. Biochimica et biophysica acta 20111201
Phosphorylation of JAK2 by serotonin 5-HT (2A) receptor activates both STAT3 and ERK1/2 pathways and increases growth of JEG-3 human placental choriocarcinoma cell. Placenta 20111201
Sustained firing of cartwheel cells in the dorsal cochlear nucleus evokes endocannabinoid release and retrograde suppression of parallel fiber synapses. The Journal of neuroscience : the official journal of the Society for Neuroscience 20111102
Lysophosphatidic acid 5 receptor induces activation of Na(+)/H(+) exchanger 3 via apical epidermal growth factor receptor in intestinal epithelial cells. American journal of physiology. Cell physiology 20111101
Aldosterone stimulates vacuolar H(+)-ATPase activity in renal acid-secretory intercalated cells mainly via a protein kinase C-dependent pathway. American journal of physiology. Cell physiology 20111101
Paroxetine-induced Ca2+ movement and death in OC2 human oral cancer cells. The Chinese journal of physiology 20111031
Cross-talk among intracellular signaling pathways mediates the diphenyl ditelluride actions on the hippocampal cytoskeleton of young rats. Chemical research in toxicology 20111017
Proteinase-activated receptor 2 sensitizes transient receptor potential vanilloid 1, transient receptor potential vanilloid 4, and transient receptor potential ankyrin 1 in paclitaxel-induced neuropathic pain. Neuroscience 20111013
Activation of orexin 1 receptors in the periaqueductal gray of male rats leads to antinociception via retrograde endocannabinoid (2-arachidonoylglycerol)-induced disinhibition. The Journal of neuroscience : the official journal of the Society for Neuroscience 20111012
In utero exposure to cocaine delays postnatal synaptic maturation of glutamatergic transmission in the VTA. Nature neuroscience 20111002
Responses of round goby (Neogobius melanostomus) olfactory epithelium to steroids released by reproductive males. Journal of comparative physiology. A, Neuroethology, sensory, neural, and behavioral physiology 20111001
Intracellular angiotensin II activates rat myometrium. American journal of physiology. Cell physiology 20110901
Multiple pathways from three types of sugar receptor sites to metabotropic transduction pathways of the blowfly: study by the whole cell-clamp experiments. Comparative biochemistry and physiology. Part A, Molecular & integrative physiology 20110901
Calcium-sensing receptor modulates extracellular Ca(2+) entry via TRPC-encoded receptor-operated channels in human aortic smooth muscle cells. American journal of physiology. Cell physiology 20110801
Nucleotides control the excitability of sensory neurons via two P2Y receptors and a bifurcated signaling cascade. Pain 20110801
Cell-type-specific CCK2 receptor signaling underlies the cholecystokinin-mediated selective excitation of hippocampal parvalbumin-positive fast-spiking basket cells. The Journal of neuroscience : the official journal of the Society for Neuroscience 20110727
Endogenous sphingosine 1-phosphate regulates spontaneous glutamate release from mossy fiber terminals via S1P(3) receptors. Life sciences 20110718
A single amino acid residue controls Ca2+ signaling by an octopamine receptor from Drosophila melanogaster. FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20110701
Coronary response to diadenosine tetraphosphate after ischemia-reperfusion in the isolated rat heart. European journal of pharmacology 20110625
TRPV4-mediated calcium influx into human bronchial epithelia upon exposure to diesel exhaust particles. Environmental health perspectives 20110601
Activation of M3 muscarinic receptors inhibits T-type Ca(2+) channel currents via pertussis toxin-sensitive novel protein kinase C pathway in small dorsal root ganglion neurons. Cellular signalling 20110601
The molecular mechanism of acylation stimulating protein regulation of adipophilin and perilipin expression: involvement of phosphoinositide 3-kinase and phospholipase C. Journal of cellular biochemistry 20110601
Effect of thapsigargin on Ca²+ fluxes and viability in human prostate cancer cells. Journal of receptor and signal transduction research 20110601
[Dysfunction of diastolic [Ca²⁺] in cardiomyocytes isolated from chagasic patients]. Revista espanola de cardiologia 20110601
Investigation of carvedilol-evoked Ca²+ movement and death in human oral cancer cells. Journal of receptor and signal transduction research 20110601
Necessary role for intracellular Ca2+ transients in initiating the apical-basolateral thinning of enveloping layer cells during the early blastula period of zebrafish development. Development, growth & differentiation 20110601
Streptococcus pneumoniae infection of host epithelial cells via polymeric immunoglobulin receptor transiently induces calcium release from intracellular stores. The Journal of biological chemistry 20110520
VEGF-induced retinal angiogenic signaling is critically dependent on Ca²⁺ signaling by Ca²⁺/calmodulin-dependent protein kinase II. Investigative ophthalmology & visual science 20110511
Effect of methoxychlor on Ca2+ handling and viability in OC2 human oral cancer cells. Basic & clinical pharmacology & toxicology 20110501
Antidepressant phenotype by inhibiting the phospholipase Cβ(1)--protein kinase Cγ pathway in the forced swim test. Neuropharmacology 20110501
Bradykinin acutely inhibits activity of the epithelial Na+ channel in mammalian aldosterone-sensitive distal nephron. American journal of physiology. Renal physiology 20110501
A fundamental role for NO-PLC signaling pathway in mediating intracellular Ca2+ oscillation in pancreatic acini. Nitric oxide : biology and chemistry 20110430
mGluR5 and NMDA receptors drive the experience- and activity-dependent NMDA receptor NR2B to NR2A subunit switch. Neuron 20110428
Direct activation of human phospholipase C by its well known inhibitor u73122. The Journal of biological chemistry 20110408
Catestatin, a neuroendocrine antimicrobial peptide, induces human mast cell migration, degranulation and production of cytokines and chemokines. Immunology 20110401
In vivo ethanol experience increases D(2) autoinhibition in the ventral tegmental area. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20110401
Stimulation of bursting in pre-Bötzinger neurons by Epac through calcium release and modulation of TRPM4 and K-ATP channels. Journal of neurochemistry 20110401
Parasagittally aligned, mGluR1-dependent patches are evoked at long latencies by parallel fiber stimulation in the mouse cerebellar cortex in vivo. Journal of neurophysiology 20110401
Roles of phospholipase D in phorbol myristate acetate-stimulated neutrophil respiratory burst. Journal of cellular and molecular medicine 20110301
Phospholipase C, Ca2+, and calmodulin signaling are required for 5-HT2A receptor-mediated transamidation of Rac1 by transglutaminase. Psychopharmacology 20110201
Deuteration as a tool in investigating the role of protons in cell signaling. Biochimica et biophysica acta 20110201
Chemotaxis of MDCK-F cells toward fibroblast growth factor-2 depends on transient receptor potential canonical channel 1. Pflugers Archiv : European journal of physiology 20110201
Thrombin-induced chemokine production in endometrial stromal cells. Human reproduction (Oxford, England) 20110201
Interleukin-6 enhances glucose-stimulated insulin secretion from pancreatic beta-cells: potential involvement of the PLC-IP3-dependent pathway. Diabetes 20110201
The opening of maitotoxin-sensitive calcium channels induces the acrosome reaction in human spermatozoa: differences from the zona pellucida. Asian journal of andrology 20110101
The mechanism of agonist induced Ca2+ signalling in intact endothelial cells studied confocally in in situ arteries. Cell calcium 20110101
Diacylglycerol regulates acute hypoxic pulmonary vasoconstriction via TRPC6. Respiratory research 20110101
The functional expression of extracellular calcium-sensing receptor in rat pulmonary artery smooth muscle cells. Journal of biomedical science 20110101
Effects of serum amyloid a and lysophosphatidylcholine on intracellular calcium concentration in human coronary artery smooth muscle cells. International heart journal 20110101
Activation of growth hormone secretagogue type 1a receptor inhibits T-type Ca2+ channel currents through pertussis toxin-sensitive novel protein kinase C pathway in mouse spermatogenic cells. Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 20110101
Sulfhydryl modification induces calcium entry through IP₃-sensitive store-operated pathway in activation-dependent human neutrophils. PloS one 20110101
Phospholipase d2 ablation ameliorates Alzheimer's disease-linked synaptic dysfunction and cognitive deficits. The Journal of neuroscience : the official journal of the Society for Neuroscience 20101208
Light activation of the phosphoinositide cycle in intrinsically photosensitive chicken retinal ganglion cells. Investigative ophthalmology & visual science 20101101
Action potential bursts in central snail neurons elicited by procaine: roles of ionic currents. The Chinese journal of physiology 20101031
Ecdysteroids elicit a rapid Ca2+ flux leading to Akt activation and increased protein synthesis in skeletal muscle cells. Steroids 20101001
Sphingosine-1-phosphate signaling in human submandibular cells. Journal of dental research 20101001
Inhibition of phospholipase C disrupts cytoskeletal organization and gravitropic growth in Arabidopsis roots. Planta 20101001
Vitellogenesis in Oncopeltus fasciatus: PLC/IP(3), DAG/PK-C pathway triggered by CaM. Journal of insect physiology 20100901
alpha-Adrenoceptor-mediated depletion of phosphatidylinositol 4, 5-bisphosphate inhibits activation of volume-regulated anion channels in mouse ventricular myocytes. British journal of pharmacology 20100901
Effect of [6]-shogaol on cytosolic Ca2+ levels and proliferation in human oral cancer cells (OC2). Journal of natural products 20100827
Signalling of sphingosine-1-phosphate in Müller glial cells via the S1P/EDG-family of G-protein-coupled receptors. Neuroscience letters 20100816
Extracellular calcium-sensing receptor mediates human bronchial epithelial wound repair. Biochemical pharmacology 20100715
Melatonin potentiates glycine currents through a PLC/PKC signalling pathway in rat retinal ganglion cells. The Journal of physiology 20100715
Visualization of Ins(1,4,5)P3 dynamics in living cells: two distinct pathways for Ins(1,4,5)P3 generation following mechanical stimulation of HSY-EA1 cells. Journal of cell science 20100701
Expression pattern and sub-cellular distribution of phosphoinositide specific phospholipase C enzymes after treatment with U-73122 in rat astrocytoma cells. Journal of cellular biochemistry 20100701
The PI-PLC inhibitor U-73122 is a potent inhibitor of the SERCA pump in smooth muscle. British journal of pharmacology 20100701
The phospholipase C inhibitor U-73122 inhibits Ca(2+) release from the intracellular sarcoplasmic reticulum Ca(2+) store by inhibiting Ca(2+) pumps in smooth muscle. British journal of pharmacology 20100701
Effect of nortriptyline on Ca²⁺ handling in SIRC rabbit corneal epithelial cells. The Chinese journal of physiology 20100630
Butyrate and propionate induced activated or non-activated neutrophil apoptosis via HDAC inhibitor activity but without activating GPR-41/GPR-43 pathways. Nutrition (Burbank, Los Angeles County, Calif.) 20100601
U73122, an aminosteroid phospholipase C inhibitor, is a potent inhibitor of cardiac phospholipase D by a PIP2-dependent mechanism. Journal of cardiovascular pharmacology 20100601
Adenosine triphosphate stimulates RANKL expression through P2Y1 receptor-cyclo-oxygenase-dependent pathway in human periodontal ligament cells. Journal of periodontal research 20100601
Effect of purinergic receptor activation on Na+-K+ pump activity, excitability, and function in depolarized skeletal muscle. American journal of physiology. Cell physiology 20100601
Ins(1,4,5)P3 interacts with PIP2 to regulate activation of TRPC6/C7 channels by diacylglycerol in native vascular myocytes. The Journal of physiology 20100501
Mathematical analysis of intercellular calcium propagation induced by adenosine triphosphate. Skin research and technology : official journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI) 20100501
The chemokine receptor CXCR7 is highly expressed in human glioma cells and mediates antiapoptotic effects. Cancer research 20100415
Activation of muscarinic M-1 cholinoceptors by curcumin to increase contractility in urinary bladder isolated from Wistar rats. Neuroscience letters 20100405
Electrical stimulation induces calcium-dependent release of NGF from cultured Schwann cells. Glia 20100401
Involvement of phospholipase C in the responses triggered by extracellular phosphatidylinositol 4-phosphate. Journal of plant physiology 20100315
The Ca2+-calmodulin-dependent kinase II is activated in papillary thyroid carcinoma (PTC) and mediates cell proliferation stimulated by RET/PTC. Endocrine-related cancer 20100301
Muscarinic cholinoceptor activation by pilocarpine triggers apoptosis in human skin fibroblast cells. Journal of cellular physiology 20100301
Involvement of TRPA1 in ET-1-induced pain-like behavior in mice. Neuroreport 20100217
Involvement of phosphatidylcholine-phospholipase C and protein kinase C in peptidoglycan-induced nuclear factor-kappaB activation and cyclooxygenase-2 expression in RAW 264.7 macrophages. Pharmacological research 20100201
Bile acid reflux contributes to development of esophageal adenocarcinoma via activation of phosphatidylinositol-specific phospholipase Cgamma2 and NADPH oxidase NOX5-S. Cancer research 20100201
Calcium entry is regulated by Zn2+ in relation to extracellular ionic environment in human airway epithelial cells. Respiratory physiology & neurobiology 20100131
Leptin excites proopiomelanocortin neurons via activation of TRPC channels. The Journal of neuroscience : the official journal of the Society for Neuroscience 20100127
Chemokine-like factor 1, a novel cytokine, induces nerve cell migration through the non-extracellular Ca2+-dependent tyrosine kinases pathway. Brain research 20100113
Neutrophil granulocytes promote the migratory activity of MDA-MB-468 human breast carcinoma cells via ICAM-1. Experimental cell research 20100101
Ghrelin stimulation of growth hormone-releasing hormone neurons is direct in the arcuate nucleus. PloS one 20100101
Induction of LRF-1/ATF3 by vasopressin in hepatocytes: role of MAP kinases. Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 20100101
Roles of Src family kinase signaling during fertilization and the first cell cycle in the marine protostome worm Cerebratulus. The International journal of developmental biology 20100101
Mechanism of carteolol-induced cytosolic Ca2+ mobilization in cultured vascular smooth muscle cells. Vascular pharmacology 20100101
Multidrug resistance protein transporter and Ins(1,4,5)P₃-sensitive Ca²+-signaling involved in adenosine triphosphate export via Gq protein-coupled NK₂-receptor stimulation with neurokinin A. Journal of pharmacological sciences 20100101
Spatial regulation of membrane fusion controlled by modification of phosphoinositides. PloS one 20100101
Visual responses in mice lacking critical components of all known retinal phototransduction cascades. PloS one 20100101
Modulation of natural killer cell function by alpha-adrenoreceptor-coupled signalling. Neuro endocrinology letters 20100101
Differential modulation of intracellular Ca2+ responses associated with calcium-sensing receptor activation in renal collecting duct cells. Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 20100101
Characterization of rhythmic Ca2+ transients in early embryonic chick motoneurons: Ca2+ sources and effects of altered activation of transmitter receptors. The Journal of neuroscience : the official journal of the Society for Neuroscience 20091202
ATP stimulates Ca(2+)-waves and gene expression in cultured human pulmonary fibroblasts. The international journal of biochemistry & cell biology 20091201
Melanin-concentrating hormone reduces somatolactin release from cultured goldfish pituitary cells. The Journal of endocrinology 20091201
Sphingosine-1-phosphate elicits receptor-dependent calcium signaling in retinal amacrine cells. Journal of neurophysiology 20091201
Prostaglandin EP3 receptor superactivates adenylyl cyclase via the Gq/PLC/Ca2+ pathway in a lipid raft-dependent manner. Biochemical and biophysical research communications 20091127
Ca2+ waves initiate antigen-stimulated Ca2+ responses in mast cells. Journal of immunology (Baltimore, Md. : 1950) 20091115
Non-selective cation channel activity is required for lysophosphatidylcholine-induced monocyte migration. Journal of cellular physiology 20091101
Oxytocin stimulates in vitro angiogenesis via a Pyk-2/Src-dependent mechanism. Experimental cell research 20091101
Differential effects of quercetin, apigenin and genistein on signalling pathways of protease-activated receptors PAR(1) and PAR(4) in platelets. British journal of pharmacology 20091101
Interleukin-1beta promotes the expression of monocyte chemoattractant protein-1 in human aorta smooth muscle cells via multiple signaling pathways. Experimental & molecular medicine 20091031
Bestrophin-1 encodes for the Ca2+-activated anion channel in hippocampal astrocytes. The Journal of neuroscience : the official journal of the Society for Neuroscience 20091014
Neurokinin 1 receptor activates transient receptor potential-like currents in noradrenergic A7 neurons in rats. Molecular and cellular neurosciences 20090901
The garlic ingredient diallyl sulfide induces Ca(2+) mobilization in Madin-Darby canine kidney cells. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20090901
EGFR-PLCgamma1 signaling mediates high glucose-induced PKCbeta1-Akt activation and collagen I upregulation in mesangial cells. American journal of physiology. Renal physiology 20090901
Arsenic trioxide modulates the central snail neuron action potential. Journal of the Formosan Medical Association = Taiwan yi zhi 20090901
[Mechanisms of nongenomic effect of 17beta-estradiol on human spermatozoa]. Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition 20090901
Protein kinase C{gamma} mediates regulation of proliferation by the serotonin 5-hydroxytryptamine receptor 2B. The Journal of biological chemistry 20090807
Effect of protease-activated receptor 2 activation on single TRPV1 channel activities in rat vagal pulmonary sensory neurons. Experimental physiology 20090801
Hypoxia-induced mitogenic factor/FIZZ1 induces intracellular calcium release through the PLC-IP(3) pathway. American journal of physiology. Lung cellular and molecular physiology 20090801
Adenoprotection of the heart involves phospholipase C-induced activation and translocation of PKC-epsilon to RACK2 in adult rat and mouse. American journal of physiology. Heart and circulatory physiology 20090801
Basic fibroblast growth factor increases intracellular magnesium concentration through the specific signaling pathways. Molecules and cells 20090731
Extracellular calcium promotes the migration of breast cancer cells through the activation of the calcium sensing receptor. Experimental cell research 20090715
Regulation of c-Fos and c-Jun gene expression by phospholipase C activity in adult cardiomyocytes. Molecular and cellular biochemistry 20090701
Contribution of the inositol 1,4,5-trisphosphate transduction cascade to the detection of 'bitter' compounds in blowflies. Comparative biochemistry and physiology. Part A, Molecular & integrative physiology 20090701
Pituitary adenylate cyclase-activating polypeptide induces somatolactin release from cultured goldfish pituitary cells. Peptides 20090701
Effect of MK-886 on Ca2+ level and viability in PC3 human prostate cancer cells. Basic & clinical pharmacology & toxicology 20090601
Phospholipase C mediated Ca2+ signals in murine urinary bladder smooth muscle. European journal of pharmacology 20090521
Activation of ROS/NF-kappaB and Ca2+/CaM kinase II are necessary for VCAM-1 induction in IL-1beta-treated human tracheal smooth muscle cells. Toxicology and applied pharmacology 20090515
Wnt5a induces simultaneous cortical axon outgrowth and repulsive axon guidance through distinct signaling mechanisms. The Journal of neuroscience : the official journal of the Society for Neuroscience 20090506
Characterization of phospholipases C beta and gamma and their possible roles in Chaetopterus egg activation. Molecular reproduction and development 20090501
Inhibition of stored Ca2+ release disrupts convergence-related cell movements in the lateral intermediate mesoderm resulting in abnormal positioning and morphology of the pronephric anlagen in intact zebrafish embryos. Development, growth & differentiation 20090501
Human brain microvascular endothelial cell traversal by Borrelia burgdorferi requires calcium signaling. Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases 20090501
Effect of thimerosal on Ca(2+) movement and viability in human oral cancer cells. Human & experimental toxicology 20090501
Calcium store-mediated signaling in sustentacular cells of the mouse olfactory epithelium. Glia 20090415
Lysophosphatidic acid induces Ca2+ mobilization and c-Myc expression in mouse embryonic stem cells via the phospholipase C pathway. Cellular signalling 20090401
Inositol trisphosphate-dependent Ca stores and mitochondria modulate slow wave activity arising from the smooth muscle cells of the guinea pig prostate gland. British journal of pharmacology 20090401
Purinergic neuron-to-glia signaling in the enteric nervous system. Gastroenterology 20090401
Phospholipase Cgamma2 is critical for Dectin-1-mediated Ca2+ flux and cytokine production in dendritic cells. The Journal of biological chemistry 20090313
VEGFR1 receptor tyrosine kinase localization to the Golgi apparatus is calcium-dependent. Experimental cell research 20090310
Phospholipase C-mediated regulation of transient receptor potential vanilloid 6 channels: implications in active intestinal Ca2+ transport. Molecular pharmacology 20090301
Endothelin downregulates SERCA2 gene and protein expression in adult rat ventricular myocytes: regulation by pertussis toxin-sensitive Gi protein and cAMP. American journal of physiology. Heart and circulatory physiology 20090301
Activity-dependent modulation of limbic dopamine D3 receptors by CaMKII. Neuron 20090212
Fast action of estrogen on intracellular calcium in dormant mouse blastocyst and its possible mechanism. Fertility and sterility 20090201
Bradykinin regulates calpain and proinflammatory signaling through TRPM7-sensitive pathways in vascular smooth muscle cells. American journal of physiology. Regulatory, integrative and comparative physiology 20090201
P2Y receptors mediate Ca2+ signaling in duodenocytes and contribute to duodenal mucosal bicarbonate secretion. American journal of physiology. Gastrointestinal and liver physiology 20090201
Role of Ca2+ mobilization and Ca2+ sensitization in 8-iso-PGF 2 alpha-induced contraction in airway smooth muscle. Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 20090201
Purinergic signalling in rat GFSHR-17 granulosa cells: an in vitro model of granulosa cells in maturing follicles. Journal of bioenergetics and biomembranes 20090201
Resynthesis of phosphatidylinositol 4,5-bisphosphate mediates adaptation of the caffeine response in rat taste receptor cells. The Journal of physiology 20090115
Cardiac microvascular endothelial cells express a functional Ca+ -sensing receptor. Journal of vascular research 20090101
UVA-induced calcium oscillations in rat mast cells. Cell calcium 20090101
Involvement of nitric oxide synthase in the mechanism of histamine-induced inhibition of Leydig cell steroidogenesis via histamine receptor subtypes in Sprague-Dawley rats. Biology of reproduction 20090101
Activation of P2X7 receptors induces CCL3 production in microglial cells through transcription factor NFAT. Journal of neurochemistry 20090101
Differential involvement of Ca2+ and actin filament in leukocyte shape change. Pharmacology 20090101
Genomic and non-genomic effect of cortisol on phagocytosis in freshwater teleost Channa punctatus: an in vitro study. Steroids 20090101
Fendiline-evoked [Ca2+]i rises and non-Ca2+-triggered cell death in human oral cancer cells. Human & experimental toxicology 20090101
Regulation of mouse lung development by the extracellular calcium-sensing receptor, CaR. The Journal of physiology 20081215
Enhanced pulsatile pressure accelerates vascular smooth muscle migration: implications for atherogenesis of hypertension. Cardiovascular research 20081201
Delta-opioid receptors activate ERK/MAP kinase via integrin-stimulated receptor tyrosine kinases. Cellular signalling 20081201
Phosphorylation of TRPV1 by neurokinin-1 receptor agonist exaggerates the capsaicin-mediated substance P release from cultured rat dorsal root ganglion neurons. Neuropharmacology 20081201
Diurnal variation in phagocytic activity of splenic phagocytes in freshwater teleost Channa punctatus: melatonin and its signaling mechanism. The Journal of endocrinology 20081201
Hypoosmotic- and pressure-induced membrane stretch activate TRPC5 channels. The Journal of physiology 20081201
Phosphatidylinositol acts through mitogen-activated protein kinase to stimulate hepatic apolipoprotein A-I secretion. Metabolism: clinical and experimental 20081201
In vitro effects of the cyclooxygenase inhibitor indomethacin and of the phospholipase-C inhibitor U-73122 on carbachol-induced contractions of porcine detrusor muscle. Fundamental & clinical pharmacology 20081201
Tibolone rapidly attenuates the GABAB response in hypothalamic neurones. Journal of neuroendocrinology 20081201
Sustained depolarization-induced propagation of [Ca2+]i oscillations in cultured DRG neurons: the involvement of extracellular ATP and P2Y receptor activation. Brain research 20081106
Constitutive activity at the cannabinoid CB1 receptor is required for behavioral response to noxious chemical stimulation of TRPV1: antinociceptive actions of CB1 inverse agonists. The Journal of neuroscience : the official journal of the Society for Neuroscience 20081105
Identification of intracellular signaling cascades mediating the PACAP-induced increase in guinea pig cardiac neuron excitability. Journal of molecular neuroscience : MN 20081101
1-[6-[[(17beta)-3-methoxyestra-1,3,5(10)-trien-17-yl]amino]hexyl]-1H-pyrrole-2,5-dione (U73122) selectively inhibits Kir3 and BK channels in a phospholipase C-independent fashion. Molecular pharmacology 20081101
Essential role of EP3 subtype in prostaglandin E2-induced adhesion of mouse cultured and peritoneal mast cells to the Arg-Gly-Asp-enriched matrix. American journal of physiology. Cell physiology 20081101
Regulation of DARPP-32 phosphorylation by three distinct dopamine D1-like receptor signaling pathways in the neostriatum. Journal of neurochemistry 20081101
[Role of phospholipase C-gamma1 signaling pathway in H(2)O(2)-induced apoptosis of PC12 cells]. Nan fang yi ke da xue xue bao = Journal of Southern Medical University 20081101
Calcium-sensing receptor signaling pathways in medullary thick ascending limb cells mediate COX-2-derived PGE2 production: functional significance. American journal of physiology. Renal physiology 20081001
Serotonin increases GABA release in rat entorhinal cortex by inhibiting interneuron TASK-3 K+ channels. Molecular and cellular neurosciences 20081001
Multiple G proteins compete for binding with the human gonadotropin releasing hormone receptor. Archives of biochemistry and biophysics 20080901
Attenuation of hypoosmotic stress-induced ANP secretion via I(Cl,swell) in renal hypertensive rat atria. Peptides 20080901
P2X7 receptor as sensitive flow sensor for ERK activation in osteoblasts. Biochemical and biophysical research communications 20080801
Role and mechanism of phosphatidylinositol-specific phospholipase C in survival and virulence of Cryptococcus neoformans. Molecular microbiology 20080801
Alpha1-adrenoceptors trigger the snake venom production cycle in secretory cells by activating phosphatidylinositol 4,5-bisphosphate hydrolysis and ERK signaling pathway. Comparative biochemistry and physiology. Part A, Molecular & integrative physiology 20080801
Phospholipase C/protein kinase C pathway mediates angiotensin II-dependent apoptosis in neonatal rat cardiac fibroblasts expressing AT1 receptor. Journal of cardiovascular pharmacology 20080801
Metabotropic receptor-activated calcium increases and store-operated calcium influx in mouse Müller cells. Investigative ophthalmology & visual science 20080701
Phosphatidylinositol 4,5-bisphosphate hydrolysis mediates histamine-induced KCNQ/M current inhibition. American journal of physiology. Cell physiology 20080701
The potential role of postsynaptic phospholipase C activity in synaptic facilitation and behavioral sensitization in Aplysia. Journal of neurophysiology 20080701
ATP/UTP activate cation-permeable channels with TRPC3/7 properties in rat cardiomyocytes. American journal of physiology. Heart and circulatory physiology 20080701
Regulation of ERK1/2 by the C. elegans muscarinic acetylcholine receptor GAR-3 in Chinese hamster ovary cells. Molecules and cells 20080630
Kaempferol and quercetin stimulate granulocyte-macrophage colony-stimulating factor secretion in human prostate cancer cells. Molecular and cellular endocrinology 20080611
Apical adenosine regulates basolateral Ca2+-activated potassium channels in human airway Calu-3 epithelial cells. American journal of physiology. Cell physiology 20080601
Nasal solitary chemoreceptor cell responses to bitter and trigeminal stimulants in vitro. Journal of neurophysiology 20080601
Activated nuclear metabotropic glutamate receptor mGlu5 couples to nuclear Gq/11 proteins to generate inositol 1,4,5-trisphosphate-mediated nuclear Ca2+ release. The Journal of biological chemistry 20080516
A novel role of hippocalcin in bFGF-induced neurite outgrowth of H19-7 cells. Journal of neuroscience research 20080515
Unexpected suppression of neuronal G protein-activated, inwardly rectifying K+ current by common phospholipase C inhibitor. Neuroscience letters 20080509
Mechanisms involved in potentiation of transient receptor potential vanilloid 1 responses by ethanol. European journal of pain (London, England) 20080501
TRPC3 is the erythropoietin-regulated calcium channel in human erythroid cells. The Journal of biological chemistry 20080418
Disruption of phospholipase Cgamma1 signalling attenuates cardiac tumor necrosis factor-alpha expression and improves myocardial function during endotoxemia. Cardiovascular research 20080401
A positive inotropic effect of ATP in the human cardiac atrium. American journal of physiology. Heart and circulatory physiology 20080401
Heterogeneity of muscarinic receptor-mediated Ca2+ responses in cultured urothelial cells from rat. American journal of physiology. Renal physiology 20080401
[Suppressive effect in vitro of resveratrol on ADP induced human platelet aggregation and its active mechanism]. Yao xue xue bao = Acta pharmaceutica Sinica 20080401
Resveratrol attenuates thromboxane A2 receptor agonist-induced platelet activation by reducing phospholipase C activity. European journal of pharmacology 20080331
Lysophosphatidic acid-stimulated interleukin-6 and -8 synthesis through LPA1 receptors on human osteoblasts. Archives of oral biology 20080301
Compound 48/80 induces endothelium-dependent and histamine release-independent relaxation in rabbit aorta. Nitric oxide : biology and chemistry 20080301
Alpha2-adrenoceptors enhance angiotensin II-induced renal vasoconstriction: role for NADPH oxidase and RhoA. Hypertension (Dallas, Tex. : 1979) 20080301
Overexpression of diacylglycerol kinase zeta inhibits endothelin-1-induced decreases in Ca2+ transients and cell shortening in mouse ventricular myocytes. Journal of molecular and cellular cardiology 20080301
Lysophosphatidylserine induces calcium signaling through Ki16425/VPC32183-sensitive GPCR in bone marrow-derived mast cells and in C6 glioma and colon cancer cells. Archives of pharmacal research 20080301
Endothelin 1 protects HN33 cells from serum deprivation-induced neuronal apoptosis through Ca(2+)-PKCalpha-ERK pathway. Experimental & molecular medicine 20080227
Thrombin increases hyposmotic taurine efflux and accelerates ICI-swell and RVD in 3T3 fibroblasts by a src-dependent EGFR transactivation. Pflugers Archiv : European journal of physiology 20080201
CaR activation increases TNF production by mTAL cells via a Gi-dependent mechanism. American journal of physiology. Renal physiology 20080201
The vanilloid receptor TRPV1 is activated and sensitized by local anesthetics in rodent sensory neurons. The Journal of clinical investigation 20080201
Role of intracellular kinases in the regulation of equine eosinophil migration and actin polymerization. Journal of veterinary pharmacology and therapeutics 20080201
Linoleic acid induces Ca2+-induced inactivation of voltage-dependent Ca2+ currents in rat pancreatic beta-cells. The Journal of endocrinology 20080201
The extracellular calcium-sensing receptor (CaSR) on human esophagus and evidence of expression of the CaSR on the esophageal epithelial cell line (HET-1A). American journal of physiology. Gastrointestinal and liver physiology 20080101
Phospholipase C signaling involvement in macrotubule assembly and activation of the mechanism regulating protoplast volume in plasmolyzed root cells of Triticum turgidum. The New phytologist 20080101
Diethylstilbestrol-induced estrogen receptor-dependent [Ca2+]i rises and apoptosis in Chinese hamster ovary (CHO) cells. Journal of receptor and signal transduction research 20080101
Dimers of the neuropeptide Y (NPY) Y2 receptor show asymmetry in agonist affinity and association with G proteins. Journal of receptor and signal transduction research 20080101
Extracellular calcium-sensing receptor mediated signalling is involved in human vascular smooth muscle cell proliferation and apoptosis. Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 20080101
[Changes in the DNA content in EGF-stimulated ciliate Tetrahymena pyriformis under effect of caffeine, KCl, and inhibitors of PLC and PKC]. Tsitologiia 20080101
Signal processes and ROS production in glucose transport regulation by thrombopoietin and granulocyte macrophage-colony stimulation factor in a human leukaemic cell line. Free radical research 20071201
Sphingosine-1-phosphate-induced oxygen free radical generation in smooth muscle cell migration requires Galpha12/13 protein-mediated phospholipase C activation. Journal of vascular surgery 20071201
Alpha2-adrenergic receptors activate cyclic AMP-response element-binding protein through arachidonic acid metabolism and protein kinase A in a subtype-specific manner. Journal of neurochemistry 20071101
Dopamine induces apoptosis in young, but not in neonatal, neurons via Ca2+-dependent signal. American journal of physiology. Cell physiology 20071101
Human malarial parasite, Plasmodium falciparum, displays capacitative calcium entry: 2-aminoethyl diphenylborinate blocks the signal transduction pathway of melatonin action on the P. falciparum cell cycle. Journal of pineal research 20071101
Roles of brain phosphatidylinositol-specific phospholipase C and diacylglycerol lipase in centrally administered histamine-induced adrenomedullary outflow in rats. European journal of pharmacology 20071001
Bursts of potential elicited by d-amphetamine in central snail neuron: effect of sodium azide. Basic & clinical pharmacology & toxicology 20071001
Tamoxifen stimulates calcium entry into human platelets. Journal of cardiovascular pharmacology 20071001
Myosin light chain kinase-independent inhibition by ML-9 of murine TRPC6 channels expressed in HEK293 cells. British journal of pharmacology 20070901
Regulation of airway goblet cell mucin secretion by tyrosine phosphorylation signaling pathways. American journal of physiology. Lung cellular and molecular physiology 20070901
In the ventral tegmental area, the membrane-mediated actions of progestins for lordosis of hormone-primed hamsters involve phospholipase C and protein kinase C. Journal of neuroendocrinology 20070901
Characterization of noradrenaline-induced increases in intracellular Ca2+ levels in Chinese hamster ovary cells stably expressing human alpha1A-adrenoceptor. Journal of pharmacological sciences 20070901
Endoplasmic reticulum is a key organella in bradykinin-triggered ATP release from cultured smooth muscle cells. Journal of pharmacological sciences 20070901
Role of interleukin-3 and signaling pathways on beta-thalassemia/HbE erythroid progenitor cell in culture. The Southeast Asian journal of tropical medicine and public health 20070901
Protease-activated receptor 4-mediated Ca2+ signaling in mouse lung alveolar epithelial cells. Life sciences 20070816
Phospholipase C beta3 is a key component in the Gbetagamma/PKCeta/PKD-mediated regulation of trans-Golgi network to plasma membrane transport. The Biochemical journal 20070815
Mechanisms for the coupling of cannabinoid receptors to intracellular calcium mobilization in rat insulinoma beta-cells. Experimental cell research 20070815
Nitric oxide is critical for inducing phosphatidic acid accumulation in xylanase-elicited tomato cells. The Journal of biological chemistry 20070720
Mechanism of membrane redistribution of protein kinase C by its ATP-competitive inhibitors. The Biochemical journal 20070715
Phospholipase C-gamma1 is required for the activation of store-operated Ca2+ channels in liver cells. The Biochemical journal 20070715
The phosphoinositide-specific phospholipase C inhibitor U73122 (1-(6-((17beta-3-methoxyestra-1,3,5(10)-trien-17-yl)amino)hexyl)-1H-pyrrole-2,5-dione) spontaneously forms conjugates with common components of cell culture medium. Drug metabolism and disposition: the biological fate of chemicals 20070701
The transfer of VLDL-associated phospholipids to activated platelets depends upon cytosolic phospholipase A2 activity. Journal of lipid research 20070701
Inositol-1,4,5-trisphosphate-mediated spontaneous activity in mouse embryonic stem cell-derived cardiomyocytes. The Journal of physiology 20070615
Adrenergic control of a constitutively active acetylcholine-regulated potassium current in canine atrial cardiomyocytes. Cardiovascular research 20070601
Stringent 3Q.1R composition of the SNARE 0-layer can be bypassed for fusion by compensatory SNARE mutation or by lipid bilayer modification. The Journal of biological chemistry 20070518
Obligatory role for phospholipase C-gamma(1) in villin-induced epithelial cell migration. American journal of physiology. Cell physiology 20070501
Suprasternal gland secretion of male short-tailed opossum induces IP3 generation in the vomeronasal organ. Biochimica et biophysica acta 20070501
Firing properties of accessory olfactory bulb mitral/tufted cells in response to urine delivered to the vomeronasal organ of gray short-tailed opossums. Chemical senses 20070501
Depolarization-induced rapid generation of 2-arachidonoylglycerol, an endogenous cannabinoid receptor ligand, in rat brain synaptosomes. Journal of biochemistry 20070501
Calcium signaling via phospholipase C is essential for proline accumulation upon ionic but not nonionic hyperosmotic stresses in Arabidopsis. Plant physiology 20070501
M1 muscarinic receptor modulation of Kir2 channels enhances temporal summation of excitatory synaptic potentials in prefrontal cortex pyramidal neurons. Journal of neurophysiology 20070501
Mechanisms involved in the regulation of mRNA for M2 muscarinic acetylcholine receptors and endothelial and neuronal NO synthases in rat atria. British journal of pharmacology 20070501
Phytosphingosine-1-phosphate stimulates chemotactic migration of L2071 mouse fibroblasts via pertussis toxin-sensitive G-proteins. Experimental & molecular medicine 20070430
Distinct targeting and fusion functions of the PX and SNARE domains of yeast vacuolar Vam7p. The Journal of biological chemistry 20070427
Cell cycle-dependent calcium oscillations in mouse embryonic stem cells. American journal of physiology. Cell physiology 20070401
Phosphoinositide-3-kinase and mitogen activated protein kinase signaling pathways mediate acute NGF sensitization of TRPV1. Molecular and cellular neurosciences 20070401
Interactions of cannabidiol with endocannabinoid signalling in hippocampal tissue. The European journal of neuroscience 20070401
AMP-activated protein kinase mediates VEGF-stimulated endothelial NO production. Biochemical and biophysical research communications 20070323
Antimicrobial peptides human beta-defensins stimulate epidermal keratinocyte migration, proliferation and production of proinflammatory cytokines and chemokines. The Journal of investigative dermatology 20070301
Parallel signaling pathways in endothelin-1-induced proliferation of U373MG astrocytoma cells. Experimental biology and medicine (Maywood, N.J.) 20070301
The carcinogen safrole increases intracellular free Ca2+ levels and causes death in MDCK cells. The Chinese journal of physiology 20070227
Defective chemoattractant-induced calcium signalling in S100A9 null neutrophils. Cell calcium 20070201
Bidirectional Ca2+ coupling of mitochondria with the endoplasmic reticulum and regulation of multimodal Ca2+ entries in rat brown adipocytes. American journal of physiology. Cell physiology 20070201
Stimulation of adenosine A1 and A2A receptors by AMP in the submucosal plexus of guinea pig small intestine. American journal of physiology. Gastrointestinal and liver physiology 20070201
(+/-)3,4-Methylenedioxyamphetamine elicits action potential bursts in a central snail neuron. Experimental neurology 20070201
Phospholipase C and Src modulate angiotensin II-induced cyclic AMP production in preglomerular microvascular smooth-muscle cells from spontaneously hypertensive rats. Journal of cardiovascular pharmacology 20070201
Effects of neurosteroids on glucocorticoid receptor-mediated gene transcription in LMCAT cells--a possible interaction with psychotropic drugs. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology 20070101
Signalling through phospholipase C interferes with clathrin-mediated endocytosis. Cellular signalling 20070101
Calcium signaling in human airway goblet cells following purinergic activation. American journal of physiology. Lung cellular and molecular physiology 20070101
Two distinct signaling pathways for regulation of spontaneous local Ca2+ release by phospholipase C in airway smooth muscle cells. Pflugers Archiv : European journal of physiology 20070101
Angiotensin II-induced MAPK phosphorylation mediated by Ras and/or phospholipase C-dependent phosphorylations but not by protein kinase C phosphorylation in cultured rat vascular smooth muscle cells. Pharmacology 20070101
Phospholipase C gamma negatively regulates Rac/Cdc42 activation in antigen-stimulated mast cells. European journal of immunology 20070101
Phospholipase C and myosin light chain kinase inhibition define a common step in actin regulation during cytokinesis. BMC cell biology 20070101
Cationic lipids involved in gene transfer mobilize intracellular calcium. Molecular membrane biology 20070101
Activation of H2O2-induced VSOR Cl- currents in HTC cells require phospholipase Cgamma1 phosphorylation and Ca2+ mobilisation. Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 20070101
Ca2+ stimulates COX-2 expression through calcium-sensing receptor in fibroblasts. Biochemical and biophysical research communications 20061229
Regulation of the cardiac L-type calcium channel in L6 cells by arginine-vasopressin. The Biochemical journal 20061215
Muscarinic acetylcholine receptor knockout mice show distinct synaptic plasticity impairments in the visual cortex. The Journal of physiology 20061215
Involvement of phosphatidylinositol-phospholipase C in immune response to Salmonella lipopolysacharide in chicken macrophage cells (HD11). International immunopharmacology 20061205
Angiotensin II activates two cation conductances with distinct TRPC1 and TRPC6 channel properties in rabbit mesenteric artery myocytes. The Journal of physiology 20061201
Phospholipase C isoforms are localized at the cleavage furrow during cytokinesis. Journal of biochemistry 20061201
Mitogen-activated protein kinase pathway mediates effects of brain-derived neurotrophic factor on differentiation of basal forebrain oligodendrocytes. Journal of neuroscience research 20061201
Effect of the stable thromboxane derivative, carbocyclic thromboxane A2, on membrane potential of rat myenteric neurones in culture. Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society 20061201
Beta-1, 3-glucan modulates PKC signalling in Lymnaea stagnalis defence cells: a role for PKC in H2O2 production and downstream ERK activation. The Journal of experimental biology 20061201
Pollen tube tip growth depends on plasma membrane polarization mediated by tobacco PLC3 activity and endocytic membrane recycling. The Plant cell 20061201
Effects of pilocarpine on the secretory acinar cells in human submandibular glands. Life sciences 20061125
Interleukin-8: novel roles in human airway smooth muscle cell contraction and migration. American journal of physiology. Cell physiology 20061101
Involvement of endoplasmic reticulum in hepatitis B virus replication. Virus research 20061101
RANTES stimulates Ca2+ mobilization and inositol trisphosphate (IP3) formation in cells transfected with G protein-coupled receptor 75. British journal of pharmacology 20061101
Blood-brain barrier traversal by African trypanosomes requires calcium signaling induced by parasite cysteine protease. The Journal of clinical investigation 20061002
Bitter stimuli induce Ca2+ signaling and CCK release in enteroendocrine STC-1 cells: role of L-type voltage-sensitive Ca2+ channels. American journal of physiology. Cell physiology 20061001
Expression of prokineticin receptors in mouse cultured astrocytes and involvement in cell proliferation. Brain research 20060927
Different receptors mediate the electrophysiological and growth cone responses of an identified neuron to applied dopamine. Neuroscience 20060915
Neurotensin selectively facilitates glutamatergic transmission in globus pallidus. Neuroscience 20060915
Effects of hyposmotic stress on exocytosis in isolated turbot, Scophthalmus maximus, hepatocytes. Journal of comparative physiology. B, Biochemical, systemic, and environmental physiology 20060901
Potent inhibition of human telomerase by U-73122. Journal of biomedical science 20060901
Serotonin stimulates GnRH secretion through the c-Src-PLC gamma1 pathway in GT1-7 hypothalamic cells. The Journal of endocrinology 20060901
Activation of the extracellular calcium-sensing receptor initiates insulin secretion from human islets of Langerhans: involvement of protein kinases. The Journal of endocrinology 20060901
Vascular endothelial growth factor increases the intracellular magnesium. Biochemical and biophysical research communications 20060825
Group I mGluR regulates the polarity of spike-timing dependent plasticity in substantia gelatinosa neurons. Biochemical and biophysical research communications 20060825
Induction of cytosolic phospholipase A2 by lipopolysaccharide in canine tracheal smooth muscle cells: involvement of MAPKs and NF-kappaB pathways. Cellular signalling 20060801
Modulation of cardiac sarcoplasmic reticulum calcium release by aenosine: a protein kinase C- dependent pathway. Molecular and cellular biochemistry 20060801
Pharmacological and molecular characterization of the mechanisms involved in prostaglandin E2-induced mouse paw edema. The Journal of pharmacology and experimental therapeutics 20060801
Pseudopterosin A inhibits phagocytosis and alters intracellular calcium turnover in a pertussis toxin sensitive site in Tetrahymena thermophila. Comparative biochemistry and physiology. Toxicology & pharmacology : CBP 20060801
VEGF-E activates endothelial nitric oxide synthase to induce angiogenesis via cGMP and PKG-independent pathways. Biochemical and biophysical research communications 20060714
Modulation of hepatocellular swelling-activated K+ currents by phosphoinositide pathway-dependent protein kinase C. American journal of physiology. Cell physiology 20060701
Norepinephrine-induced changes in gene expression of phospholipase C in cardiomyocytes. Journal of molecular and cellular cardiology 20060701
Effects of interleukin-1 on calcium signaling and the increase of filamentous actin in isolated and in situ articular chondrocytes. Arthritis and rheumatism 20060701
Muscarinic cholinoceptor activation modulates DNA synthesis and CD40 expression in fibroblast cells. Autonomic & autacoid pharmacology 20060701
Glucagon activates Ca2+ and Cl- channels in rat hepatocytes. The Journal of physiology 20060615
Apelin stimulates myosin light chain phosphorylation in vascular smooth muscle cells. Arteriosclerosis, thrombosis, and vascular biology 20060601
Neurotensin enhances nitric oxide generation via the JAK2-STAT1 pathway in murine macrophage Raw264.7 cells during costimulation with LPS and IFNgamma. Neuropeptides 20060601
Evidence that phospholipase-C-dependent, calcium-independent mechanisms are required for directional migration of T-lymphocytes in response to the CCR4 ligands CCL17 and CCL22. Journal of leukocyte biology 20060601
Substance P release evoked by capsaicin or potassium from rat cultured dorsal root ganglion neurons is conversely modulated with bradykinin. Journal of neurochemistry 20060601
Mechanical hyperalgesia induced by endothelin-1 in rats is mediated via phospholipase C, protein kinase C, and MAP kinases. Experimental biology and medicine (Maywood, N.J.) 20060601
Role of phospholipase C-gamma in NGF-stimulated differentiation and gene induction. Acta biologica Hungarica 20060601
The role of tyrosine kinase in prostaglandin E2 and vanadate-evoked contractions in rabbit duodenum in vitro. Journal of physiology and pharmacology : an official journal of the Polish Physiological Society 20060601
Gi-coupled receptors mediate phosphorylation of CPI-17 and MLC20 via preferential activation of the PI3K/ILK pathway. The Biochemical journal 20060515
Extracellular ATP activates ERK1/ERK2 via a metabotropic P2Y1 receptor in a Ca2+ independent manner in differentiated human skeletal muscle cells. Biochemical pharmacology 20060514
Critical role of phospholipase Cgamma1 in the generation of H2O2-evoked [Ca2+]i oscillations in cultured rat cortical astrocytes. The Journal of biological chemistry 20060512
Equol and para-ethyl-phenol stimulate prostaglandin F(2alpha) secretion in bovine corpus luteum: intracellular mechanisms of action. Prostaglandins & other lipid mediators 20060501
Human TRPC6 expressed in HEK 293 cells forms non-selective cation channels with limited Ca2+ permeability. The Journal of physiology 20060415
Phospholipase C-delta1 is a critical target for tumor necrosis factor receptor-mediated protection against adriamycin-induced cardiac injury. Cancer research 20060415
Primary evidence for involvement of IP3 in heat-shock signal transduction in Arabidopsis. Cell research 20060401
Sex-specific regulation of growth plate chondrocytes by estrogen is via multiple MAP kinase signaling pathways. Biochimica et biophysica acta 20060401
Two distinct Ca2+ compartments show differential sensitivity to thrombin, ADP and vasopressin in human platelets. Cellular signalling 20060301
Testosterone induces an intracellular calcium increase by a nongenomic mechanism in cultured rat cardiac myocytes. Endocrinology 20060301
Lysophosphatidylserine stimulates L2071 mouse fibroblast chemotactic migration via a process involving pertussis toxin-sensitive trimeric G-proteins. Molecular pharmacology 20060301
Flagellin of Pseudomonas aeruginosa inhibits Na+ transport in airway epithelia. FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20060301
Characterization of muscarinic receptor-mediated cationic currents in longitudinal smooth muscle cells of mouse small intestine. Journal of pharmacological sciences 20060301
Potentiation of nicotinic currents by bradykinin in the paratracheal ganglia neurons of rats. European journal of pharmacology 20060215
Contribution of lipid mediators to the regulation of phosphatidylcholine synthesis by angiotensin. Biochimica et biophysica acta 20060201
Role of phospholipase C and diacylglyceride lipase pathway in arachidonic acid release and acetylcholine-induced vascular relaxation in rabbit aorta. American journal of physiology. Heart and circulatory physiology 20060101
Ionic mechanisms of histamine-induced responses in guinea pig intracardiac neurons. American journal of physiology. Regulatory, integrative and comparative physiology 20060101
Protein kinase C (PKC)-delta/-epsilon mediate the PKC/Akt-dependent phosphorylation of extracellular signal-regulated kinases 1 and 2 in MCF-7 cells stimulated by bradykinin. The Journal of endocrinology 20060101
Mechanism of non-capacitative Ca2+ influx in response to bradykinin in vascular endothelial cells. Journal of vascular research 20060101
The neuroprotective adenosine-activated signal transduction pathway involves activation of phospholipase C. Nucleosides, nucleotides & nucleic acids 20060101
Nonylphenol-induced Ca2+ elevation and Ca2+-independent cell death in human osteosarcoma cells. Toxicology letters 20051230
Participation of tyrosine kinase and phospholipase Cgamma in isradipine-induced proliferation of cultured human gingival fibroblasts. European journal of medical research 20051207
Similar mechanisms regulate protein exocytosis from the salivary glands of ixodid and argasid ticks. Journal of insect physiology 20051201
Binding of PLCdelta1PH-GFP to PtdIns(4,5)P2 prevents inhibition of phospholipase C-mediated hydrolysis of PtdIns(4,5)P2 by neomycin. Acta pharmacologica Sinica 20051201
Rhythmic expression of adenylyl cyclase VI contributes to the differential regulation of serotonin N-acetyltransferase by bradykinin in rat pineal glands. The Journal of biological chemistry 20051118
Inhibitory effects of U73122 and U73343 on Ca2+ influx and pore formation induced by the activation of P2X7 nucleotide receptors in mouse microglial cell line. Biochimica et biophysica acta 20051115
Differential CCR1-mediated chemotaxis signaling induced by human CC chemokine HCC-4/CCL16 in HOS cells. FEBS letters 20051107
Non-specific effects of 4-chloro-m-cresol may cause calcium flux and respiratory burst in human neutrophils. Biochemical and biophysical research communications 20051104
The phosphorylation of phospholipase C-gamma1, Raf-1, MEK, and ERK1/2 induced by a conserved retroviral peptide. Peptides 20051101
Strontium promotes calcium oscillations in mouse meiotic oocytes and early embryos through InsP3 receptors, and requires activation of phospholipase and the synergistic action of InsP3. Human reproduction (Oxford, England) 20051101
Ca2+ is mobilized by hydroxyl radical but not by superoxide in RTH-149 cells: the oxidative switching-on of Ca2+ signaling. Cell calcium 20051101
Endothelial cell calpain activity facilitates lymphocyte diapedesis. American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20051101
Intraplatelet signaling mechanisms of the priming effect of matrix metalloproteinase-2 on platelet aggregation. Journal of thrombosis and haemostasis : JTH 20051101
The cold-induced early activation of phospholipase C and D pathways determines the response of two distinct clusters of genes in Arabidopsis cell suspensions. Plant physiology 20051101
NF-kappaB and Hsp70 are involved in the phospholipase Cgamma1 signaling pathway in colorectal cancer cells. Life sciences 20051014
Mechanisms underlying the inhibitory effects induced by pituitary adenylate cyclase-activating peptide in mouse ileum. European journal of pharmacology 20051003
Calcium dependence of proteinase-activated receptor 2 and cholecystokinin-mediated amylase secretion from pancreatic acini. American journal of physiology. Gastrointestinal and liver physiology 20051001
Effects of a new isoquinolinone derivative on induction of action potential bursts in central snail neuron. Pharmacology 20051001
ANG II increases 2-deoxyglucose uptake in mouse embryonic stem cells. Life sciences 20050826
Effects of rolipram on induction of action potential bursts in central snail neurons. Experimental neurology 20050801
Activation of phosphoinositide 3-kinase, protein kinase C, and extracellular signal-regulated kinase is required for oridonin-enhanced phagocytosis of apoptotic bodies in human macrophage-like U937 cells. Journal of pharmacological sciences 20050801
Signaling pathway in nerve growth factor induced histamine release from rat mast cells. Inflammation research : official journal of the European Histamine Research Society ... [et al.] 20050801
Molecular mechanism and functional implications of thrombin-mediated tyrosine phosphorylation of PKCdelta in platelets. Blood 20050715
Mechanisms of gelsolin-dependent and -independent EGF-stimulated cell motility in a human lung epithelial cell line. Experimental cell research 20050701
Ethanol triggers neural crest apoptosis through the selective activation of a pertussis toxin-sensitive G protein and a phospholipase Cbeta-dependent Ca2+ transient. Alcoholism, clinical and experimental research 20050701
Phospholipase C-beta3 mediates the thrombin-induced Ca2+ response in glial cells. Molecules and cells 20050630
Prostaglandin E2 stimulates fibronectin expression through EP1 receptor, phospholipase C, protein kinase Calpha, and c-Src pathway in primary cultured rat osteoblasts. The Journal of biological chemistry 20050617
Protein kinase C-independent pathway for NADPH oxidase activation in guinea pig peritoneal polymorphonuclear leukocytes by cytochalasin D. Archives of biochemistry and biophysics 20050615
Calcium oscillations in interstitial cells of the rabbit urethra. The Journal of physiology 20050601
Artocarpol A stimulation of superoxide anion generation in neutrophils involved the activation of PLC, PKC and p38 mitogen-activated PK signaling pathways. British journal of pharmacology 20050601
Novel type of Gq/11 protein-coupled neurosteroid receptor sensitive to endocrine disrupting chemicals in mast cell line (RBL-2H3). British journal of pharmacology 20050601
The role of intracellular Ca2+ in the regulation of proteinase-activated receptor-2 mediated nuclear factor kappa B signalling in keratinocytes. British journal of pharmacology 20050601
Characteristics of odorant elicited calcium fluxes in acutely-isolated chick olfactory neurons. Journal of comparative physiology. A, Neuroethology, sensory, neural, and behavioral physiology 20050601
Cannabinoids produce neuroprotection by reducing intracellular calcium release from ryanodine-sensitive stores. Neuropharmacology 20050601
Involvement of phospholipase C and intracellular calcium signaling in the gonadotropin-releasing hormone regulation of prolactin release from lactotrophs of tilapia (Oreochromis mossambicus). General and comparative endocrinology 20050515
Brain phospholipase C/diacylglycerol lipase are involved in bombesin BB2 receptor-mediated activation of sympatho-adrenomedullary outflow in rats. European journal of pharmacology 20050509
Mechanotransduction by integrin is essential for IL-6 secretion from endothelial cells in response to uniaxial continuous stretch. American journal of physiology. Cell physiology 20050501
Varicosity-Schwann cell interactions mediated by ATP in the mouse vas deferens. Journal of neurophysiology 20050501
The aminosteroid phospholipase C antagonist U-73122 (1-[6-[[17-beta-3-methoxyestra-1,3,5(10)-trien-17-yl]amino]hexyl]-1H-pyrrole-2,5-dione) potently inhibits human 5-lipoxygenase in vivo and in vitro. Molecular pharmacology 20050501
Potentiation of P2Y receptors by physiological elevations of extracellular K+ via a mechanism independent of Ca2+ influx. Molecular pharmacology 20050501
Aminoglycosides induce acute cell signaling and chronic cell death in renal cells that express the calcium-sensing receptor. Journal of the American Society of Nephrology : JASN 20050501
Phytoestrogens modulate prostaglandin production in bovine endometrium: cell type specificity and intracellular mechanisms. Experimental biology and medicine (Maywood, N.J.) 20050501
Src homology domains in phospholipase C-gamma1 mediate its anti-apoptotic action through regulating the enzymatic activity. Journal of neurochemistry 20050501
The effect of prostaglandin E1 on ion currents of NG108-15 cells. Prostaglandins & other lipid mediators 20050501
PI-PLCbeta is involved in the modulation of the proximal tubule Na+-ATPase by angiotensin II. Regulatory peptides 20050415
Evidence for signaling via gap junctions from smooth muscle to endothelial cells in rat mesenteric arteries: possible implication of a second messenger. Cell calcium 20050401
Relationship between membrane phosphatidylinositol-4,5-bisphosphate and receptor-mediated inhibition of native neuronal M channels. The Journal of neuroscience : the official journal of the Society for Neuroscience 20050330
Modulation of the actin cytoskeleton via gelsolin regulates vacuolar H+-ATPase recycling. The Journal of biological chemistry 20050304
Alteration of cyclopiazonic acid-mediated contracture of mouse diaphragm after denervation. Pharmacology 20050301
Involvement of phospholipase C in Yersinia enterocolitica heat stable enterotoxin (Y-STa) mediated rise in intracellular calcium level in rat intestinal epithelial cells. Toxicon : official journal of the International Society on Toxinology 20050301
Sphingosine-1-phosphate induces early response gene expression in C6 glioma cells. Brain research. Molecular brain research 20050218
Inhibition of phospholipase C-independent exocytotic responses in rat peritoneal mast cells by U73122. Regulatory peptides 20050215
Lysophosphatidic acid triggers calcium entry through a non-store-operated pathway in human neutrophils. Journal of leukocyte biology 20050201
alpha1A-adrenoceptors activate glucose uptake in L6 muscle cells through a phospholipase C-, phosphatidylinositol-3 kinase-, and atypical protein kinase C-dependent pathway. Endocrinology 20050201
Atypical protein kinase C is a novel mediator of dopamine-enhanced firing in nucleus accumbens neurons. The Journal of neuroscience : the official journal of the Society for Neuroscience 20050126
Diacylglycerol kinase activity in purified basolateral membranes of kidney tubules. I. Evidence for coupling with phospholipase C. The international journal of biochemistry & cell biology 20050101
Secretion of ATP from Schwann cells in response to uridine triphosphate. The European journal of neuroscience 20050101
Different pathways leading to activation of extracellular signal-regulated kinase and p38 MAP kinase by formyl-methionyl-leucyl-phenylalanine or platelet activating factor in human neutrophils. Journal of biomedical science 20050101
Pituitary adenylate cyclase activating polypeptide reduces A-type K+ currents and caspase activity in cultured adult mouse olfactory neurons. Neuroscience 20050101
Group I metabotropic glutamate receptors reduce excitotoxic injury and may facilitate neurogenesis. Neuropharmacology 20050101
Whole-cell recording of light-evoked photoreceptor responses in a slice preparation of the cuttlefish retina. Visual neuroscience 20050101
PKC alpha depletion in RAW264.7 macrophages following microbial/IFNgamma stimulation is PC-PLC-mediated. Antioxidants & redox signaling 20050101
BDNF acutely modulates synaptic transmission and calcium signalling in developing cortical neurons. Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 20050101
Metabolic arrest and its regulation in anoxic eel hepatocytes. Physiological and biochemical zoology : PBZ 20050101
Polycystin-1 activates the calcineurin/NFAT (nuclear factor of activated T-cells) signaling pathway. The Journal of biological chemistry 20041231
Delayed and sustained activation of extracellular signal-regulated kinase in human keratinocytes by UVA: implications in carcinogenesis. The Journal of biological chemistry 20041217
Diacylglycerol and its formation by phospholipase C regulate Rab- and SNARE-dependent yeast vacuole fusion. The Journal of biological chemistry 20041217
Neuromedin U elicits cytokine release in murine Th2-type T cell clone D10.G4.1. Journal of immunology (Baltimore, Md. : 1950) 20041215
Extracellular zinc triggers ERK-dependent activation of Na+/H+ exchange in colonocytes mediated by the zinc-sensing receptor. The Journal of biological chemistry 20041210
Substance P promotes sleep in the ventrolateral preoptic area of rats. Brain research 20041203
Inhibition of PLC improves postischemic recovery in isolated rat heart. American journal of physiology. Heart and circulatory physiology 20041201
Nitric oxide inhibits IgE-dependent cytokine production and Fos and Jun activation in mast cells. Journal of immunology (Baltimore, Md. : 1950) 20041201
EP1- and EP3-receptors mediate prostaglandin E2-induced constriction of porcine large cerebral arteries. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 20041201
Cu,Zn superoxide dismutase increases intracellular calcium levels via a phospholipase C-protein kinase C pathway in SK-N-BE neuroblastoma cells. Biochemical and biophysical research communications 20041112
Molecular mechanisms for activation of voltage-independent Ca2+ channels by endothelin-1/endothelin-A receptors. Journal of cardiovascular pharmacology 20041101
Capsazepine elevates intracellular Ca2+ in human osteosarcoma cells, questioning its selectivity as a vanilloid receptor antagonist. Life sciences 20041008
Inhibitory regulation of constitutive transient receptor potential-like cation channels in rabbit ear artery myocytes. The Journal of physiology 20041001
Exploring the pharmacology of the leukotriene B4 receptor BLT1, without the confounding effects of BLT2. European journal of pharmacology 20040919
Brain phospholipase C-diacylglycerol lipase pathway is involved in vasopressin-induced release of noradrenaline and adrenaline from adrenal medulla in rats. European journal of pharmacology 20040919
Sensitization of vanilloid receptor 1 induced by bradykinin via the activation of second messenger signaling cascades in rat primary afferent neurons. European journal of pharmacology 20040913
Calmodulin-mediated activation of Akt regulates survival of c-Myc-overexpressing mouse mammary carcinoma cells. The Journal of biological chemistry 20040910
Depolarization of skeletal muscle cells induces phosphorylation of cAMP response element binding protein via calcium and protein kinase Calpha. The Journal of biological chemistry 20040910
Novel role of phospholipase C-delta1: regulation of liver mitochondrial Ca2+ uptake. American journal of physiology. Gastrointestinal and liver physiology 20040901
Phospholipase C activator m-3M3FBS affects Ca2+ homeostasis independently of phospholipase C activation. British journal of pharmacology 20040901
Dopamine D1 and D2 receptor Co-activation generates a novel phospholipase C-mediated calcium signal. The Journal of biological chemistry 20040820
Interaction of ovokinin(2-7) with vascular bradykinin 2 receptors. Regulatory peptides 20040815
Involvement of MAP-kinase, PI3-kinase and EGF-receptor in the stimulatory effect of Neurotensin on DNA synthesis in PC3 cells. Regulatory peptides 20040815
Functional re-establishment of the perforant pathway in organotypic co-cultures on microelectrode arrays. Brain research 20040813
Subcortical Ca2+ waves sneaking under the plasma membrane in endothelial cells. Circulation research 20040806
Effect of the antidepressant maprotiline on calcium movement and the viability of renal tubular cells. Archives of toxicology 20040801
Identifying pathways involved in leptin-dependent aggregation of human platelets. International journal of obesity and related metabolic disorders : journal of the International Association for the Study of Obesity 20040801
Continuous phosphatidylinositol metabolism is required for cleavage of crane fly spermatocytes. Journal of cell science 20040801
Effect of carvedilol on Ca2+ movement and cytotoxicity in human MG63 osteosarcoma cells. Basic & clinical pharmacology & toxicology 20040801
Phospholipase C may be involved in norepinephrine-induced cardiac hypertrophy. Biochemical and biophysical research communications 20040730
Inverted signaling hierarchy between RAS and RAC in T-lymphocytes. Oncogene 20040729
Acute effects of testosterone on intracellular Ca2+ kinetics in rat coronary endothelial cells are exerted via aromatization to estrogens. American journal of physiology. Heart and circulatory physiology 20040701
Modulation of cyclic AMP production by signal transduction pathways in preglomerular microvessels and microvascular smooth muscle cells. The Journal of pharmacology and experimental therapeutics 20040701
An essential role of Cav1.2 L-type calcium channel for urinary bladder function. FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20040701
Endothelin 1 and 3 enhance neuronal nitric oxide synthase activity through ETB receptors involving multiple signaling pathways in the rat anterior hypothalamus. Peptides 20040701
Effects of myo-inositol versus fluoxetine and imipramine pretreatments on serotonin 5HT2A and muscarinic acetylcholine receptors in human neuroblastoma cells. Metabolic brain disease 20040601
P2Y receptor-mediated Ca(2+) signaling increases human vascular endothelial cell permeability. Journal of pharmacological sciences 20040601
In vivo activity of a phospholipase C inhibitor, 1-(6-((17beta-3-methoxyestra-1,3,5(10)-trien-17-yl)amino)hexyl)-1H-pyrrole-2,5-dione (U73122), in acute and chronic inflammatory reactions. The Journal of pharmacology and experimental therapeutics 20040501
Evidence for the involvement of protein kinase C in acidic pH-induced contraction in spontaneously hypertensive rat aorta. Pharmacology 20040501
Slow calcium signals after tetanic electrical stimulation in skeletal myotubes. Biophysical journal 20040501
Ergosterol elicits oxidative burst in tobacco cells via phospholipase A2 and protein kinase C signal pathway. Plant physiology and biochemistry : PPB 20040501
Modulatory effect of endothelin-1 and -3 on neuronal norepinephrine release in the rat posterior hypothalamus. Regulatory peptides 20040415
Suppression of receptor-mediated Ca2+ mobilization and functional leukocyte responses by hyperforin. Biochemical pharmacology 20040415
CysLT1 signal transduction in differentiated U937 cells involves the activation of the small GTP-binding protein Ras. Biochemical pharmacology 20040415
ET-1 induces cortical spreading depression via activation of the ETA receptor/phospholipase C pathway in vivo. American journal of physiology. Heart and circulatory physiology 20040401
The neuropeptides vasoactive intestinal peptide (VIP) and pituitary adenylate cyclase activating polypeptide (PACAP) modulate several biochemical pathways in human leukemic myeloid cells. Journal of neuroimmunology 20040401
Mechanisms of action of melanin-concentrating hormone in the teleost fish erythrophoroma cell line (GEM-81). General and comparative endocrinology 20040401
Cellular injury induces activation of MAPK via P2Y receptors. Journal of cellular biochemistry 20040401
Lysophosphatidic acid induces hypertrophy of neonatal cardiac myocytes via activation of Gi and Rho. Journal of molecular and cellular cardiology 20040401
Progesterone stimulation by LH involves the phospholipase-C pathway in bovine luteal cells. The Journal of reproduction and development 20040401
The phospholipase C-InsP3 pathway is involved in calcium mobilization induced by growth hormone in hepatocytes. Growth hormone & IGF research : official journal of the Growth Hormone Research Society and the International IGF Research Society 20040401
Noxious cold ion channel TRPA1 is activated by pungent compounds and bradykinin. Neuron 20040325
The alteration of intracellular signaling on the smooth muscle cells contraction in cat esophagitis. Life sciences 20040312
Characterization of G proteins involved in activation of nonselective cation channels and arachidonic acid release by norepinephrine/alpha1A-adrenergic receptors. American journal of physiology. Cell physiology 20040301
Role of Galphaq in smooth muscle cell proliferation. Journal of vascular surgery 20040301
Multiple pathways regulate the induction of genes during zoosporogenesis in Phytophthora infestans. Molecular plant-microbe interactions : MPMI 20040301
Human beta-defensin-2 functions as a chemotactic agent for tumour necrosis factor-alpha-treated human neutrophils. Immunology 20040301
Mechanism of activation of ADP-induced platelet aggregation under the influence of oxidatively modified fibrinogen. Bulletin of experimental biology and medicine 20040301
Expression of adhesion molecules by sphingosine 1-phosphate and histamine in endothelial cells. European journal of pharmacology 20040220
Localised calcium release events in cells from the muscle of guinea-pig gastric fundus. The Journal of physiology 20040201
Thyrotropin-releasing hormone increases phospholipase D activity through stimulation of protein kinase C in GH3 cells. Endocrine 20040201
Calcineurin phosphatase activity: activation by glucocorticoids and role of intracellular calcium. Transplantation 20040127
Effect of Y-24180 on Ca2+ movement and proliferation in renal tubular cells. Life sciences 20040102
Stress impairs alpha(1A) adrenoceptor-mediated noradrenergic facilitation of GABAergic transmission in the basolateral amygdala. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20040101
Phospholipase C, but not InsP3 or DAG, -dependent activation of the muscarinic receptor-operated cation current in guinea-pig ileal smooth muscle cells. British journal of pharmacology 20040101
The action mode of lysophosphatidylcholine in human monocytes. Journal of pharmacological sciences 20040101
Calcium modulates osmosensitive taurine efflux in HeLa cells. Neurochemical research 20040101
Induction of cyclooxygenase-2 expression in human tracheal smooth muscle cells by interleukin-1beta: involvement of p42/p44 and p38 mitogen-activated protein kinases and nuclear factor-kappaB. Journal of biomedical science 20040101
Intracellular Ca2+ stimulates the binding to androgen receptors in platelets. Steroids 20040101
The PLC-PKC cascade is required for IL-1beta-dependent Erk and Akt activation: their role in proliferation. International journal of oncology 20031201
Helicobacter pylori-induced homotypic phagosome fusion in human monocytes is independent of the bacterial vacA and cag status. Cellular microbiology 20031201
Dependence of cyclopiazonic-acid-induced muscle contractures on extracellular Ca2+. Canadian journal of physiology and pharmacology 20031201
Pharmacological analysis of signal transduction pathways required for oxidative burst in chicken heterophils stimulated by a Toll-like receptor 2 agonist. International immunopharmacology 20031101
Modulation of delayed rectifier potassium current by angiotensin II in CATH.a cells. Biochemical and biophysical research communications 20031024
The G-protein-coupled receptor GCR1 regulates DNA synthesis through activation of phosphatidylinositol-specific phospholipase C. Plant physiology 20031001
Adenosine-induced IL-6 expression in pituitary folliculostellate cells is mediated via A2b adenosine receptors coupled to PKC and p38 MAPK. British journal of pharmacology 20031001
Synergism interaction between arachidonic acid by 5-hydroxytryptamine in human platelet aggregation is mediated through multiple signalling pathways. Acta pharmacologica Sinica 20031001
Mechanosensitive cation channels in arterial smooth muscle cells are activated by diacylglycerol and inhibited by phospholipase C inhibitor. Circulation research 20030919
ADP-ribosylation factor-dependent phospholipase D activation by the M3 muscarinic receptor. The Journal of biological chemistry 20030905
Oxytocin receptor elicits different EGFR/MAPK activation patterns depending on its localization in caveolin-1 enriched domains. Oncogene 20030904
Screening of second messengers involved in photocyte bioluminescence control of three ophiuroid species (Ophiuroidea: Echinodermata). The Journal of experimental biology 20030901
Hg2+ signaling in trout hepatoma (RTH-149) cells: involvement of Ca2+-induced Ca2+ release. Cell calcium 20030901
Signaling role for phospholipase C gamma 2 in platelet glycoprotein Ib alpha calcium flux and cytoskeletal reorganization. Involvement of a pathway distinct from FcR gamma chain and Fc gamma RIIA. The Journal of biological chemistry 20030829
Sustained intracellular Ca2+ elevation induced by a brief BDNF application in rat visual cortex neurons. Neuroreport 20030806
Phospholipase C inhibitors suppress spontaneous mechanical activity of guinea pig urinary bladder smooth muscle. Biological & pharmaceutical bulletin 20030801
Phospholipase C-dependent Ca2+ release by worm and mammal sperm factors. Biochemical and biophysical research communications 20030718
Role of protein kinase C in BSA-AGE-mediated inducible nitric oxide synthase expression in RAW 264.7 macrophages. Biochemical pharmacology 20030715
Requirement for intracellular calcium modulation in zebrafish dorsal-ventral patterning. Developmental biology 20030715
Phospholipase C and protein kinase C involvement in mouse embryonic stem-cell proliferation and apoptosis. Reproduction (Cambridge, England) 20030701
Endogenous somatostatin receptors mobilize calcium from inositol 1,4,5-trisphosphate-sensitive stores in NG108-15 cells. Brain research 20030613
Role of cyclooxygenase-1 and -2, phospholipase C, and protein kinase C in prostaglandin-mediated gastroprotection. The Journal of pharmacology and experimental therapeutics 20030601
Enhanced release of IL-1beta and TNF-alpha following endotoxin challenge from rat alveolar macrophages cultured in low-mg(2+) medium. Magnesium research 20030601
Evidence for the involvement of a phospholipase C--protein kinase C signaling pathway in insulin stimulated glucose transport in skeletal muscle. Life sciences 20030523
The involvement of specific phospholipase C isozymes in catecholamine release from digitonin permeabilized bovine adrenal medullary chromaffin cells. Neuroscience letters 20030515
Polyamines as olfactory stimuli in the goldfish Carassius auratus. The Journal of experimental biology 20030501
Molecular mechanisms for the activation of Ca2+-permeable nonselective cation channels by endothelin-1 in C6 glioma cells. Biochemical pharmacology 20030501
The phospholipase C-IP3 pathway is involved in muscarinic antinociception. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20030501
The use of selective pharmacological inhibitors to delineate signal transduction pathways activated during complement receptor-mediated degranulation in chicken heterophils. International immunopharmacology 20030501
Mechanisms involved in the stimulation of prostacyclin synthesis by human lymphocytes in human umbilical vein endothelial cells. British journal of pharmacology 20030501
Effects of methyl p-hydroxybenzoate (methyl paraben) on Ca2+ concentration and histamine release in rat peritoneal mast cells. British journal of pharmacology 20030501
Is Ca2+ release from internal stores involved in membrane excitation in characean cells? Plant & cell physiology 20030501
Two potential Ca(2+)-mobilizing processes depend on the abscisic acid concentration and growth temperature in the Arabidopsis stomatal guard cell. Journal of plant physiology 20030501
Effect of NPC-14686 (Fmoc-L-homophenylalanine) on intracellular Ca2+ levels in human hepatoma cells. Life sciences 20030425
A novel, voltage-dependent nonselective cation current activated by insulin in guinea pig isolated ventricular myocytes. Circulation research 20030418
A novel action of insulin on cardiac membrane. Circulation research 20030418
Distinct regulation of expressed calcium channels 2.3 in Xenopus oocytes by direct or indirect activation of protein kinase C. Brain research 20030411
Activation of human monocytic cells by lysophosphatidic acid and sphingosine-1-phosphate. Cellular signalling 20030401
Prostaglandin (PG) F(2alpha) receptor expression and signaling in human endometrium: role of PGF(2alpha) in epithelial cell proliferation. The Journal of clinical endocrinology and metabolism 20030401
Effect of SNI-2011 on amylase secretion from parotid tissue in rats and in neuronal nitric oxide synthase knockout mice. European journal of pharmacology 20030319
Protein kinase C is necessary for recovery from the thyrotropin-releasing hormone-induced r-ERG current reduction in GH3 rat anterior pituitary cells. The Journal of physiology 20030315
Vortex-mediated mechanical stress induces integrin-dependent cell adhesion mediated by inositol 1,4,5-trisphosphate-sensitive Ca2+ release in THP-1 cells. The Journal of biological chemistry 20030314
Modulation of cytosolic calcium levels in osteoblast-like osteosarcoma cells by olpadronate and its amino-derivative IG-9402. Calcified tissue international 20030301
Involvement of G(q/11) in signal transduction in the mammalian vomeronasal organ. The Journal of experimental biology 20030301
Chlorophyll antenna size adjustments by irradiance in Dunaliella salina involve coordinate regulation of chlorophyll a oxygenase (CAO) and Lhcb gene expression. Plant molecular biology 20030301
Synaptic Drosophila UNC-13 is regulated by antagonistic G-protein pathways via a proteasome-dependent degradation mechanism. Journal of neurobiology 20030215
P2Y-receptor regulates size of endothelial cells in an intracellular Ca2+ dependent manner. Life sciences 20030214
Role of phospholipase C-beta in the modulation of epithelial tight junction permeability. The Journal of pharmacology and experimental therapeutics 20030201
Enhancement of glucose transport in rat thymocytes by different radical sources. Free radical research 20030201
Functional role of ryanodine-sensitive Ca2+ stores in acidic pH-induced contraction in Wistar Kyoto rat aorta. Life sciences 20030131
Coexpression of delta-opioid receptors with micro receptors in GH3 cells changes the functional response to micro agonists from inhibitory to excitatory. Molecular pharmacology 20030101
Integrity of actin-network is involved in uridine 5'-triphosphate evoked store-operated Ca2+ entry in bovine adrenocortical fasciculata cells. Journal of pharmacological sciences 20030101
Involvement of high-density lipoprotein in stimulatory effect of hormones supporting function of the bovine corpus luteum. Acta veterinaria Hungarica 20030101
Involvement of phosphatidic acid in both degranulation and oxidative activity in fMet-Leu-Phe stimulated polymorphonuclear leukocytes. Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 20030101
Phospholipase C inhibitor U73122 attenuates the dipsogenic response induced by angiotensin II. Proceedings of the Western Pharmacology Society 20030101
Endothelial NADPH oxidase: mechanism of activation by low-density lipoprotein. Endothelium : journal of endothelial cell research 20030101
[Effect of EGF on the intracellular distribution of heat-shock proteins in A431 cells]. Tsitologiia 20030101
Chemokine-independent preference for T-helper-1 cells in transendothelial migration. The Journal of biological chemistry 20021227
Differential activation of ion channels by inositol 1,4,5-trisphosphate (IP3)- and ryanodine-sensitive calcium stores in rat basilar artery vasomotion. The Journal of physiology 20021201
Mechanism of action of the growth hormone secretagogue, L-692,585, on isolated porcine somatotropes. The Journal of endocrinology 20021201
Phospholipase C axis is the preferential pathway leading to PKC activation following PTH or PTHrP stimulation in human term placenta. Life sciences 20021129
Signaling pathways for TNF production induced by human aminoacyl-tRNA synthetase-associating factor, p43. Cytokine 20021124
Mechanism of regulation of casein kinase I activity by group I metabotropic glutamate receptors. The Journal of biological chemistry 20021122
Serotonin-induced MMP-13 production is mediated via phospholipase C, protein kinase C, and ERK1/2 in rat uterine smooth muscle cells. The Journal of biological chemistry 20021108
Induction of cancer cell migration by epidermal growth factor is initiated by specific phosphorylation of tyrosine 1248 of c-erbB-2 receptor via EGFR. FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20021101
Chlorpromazine inhibits the glucocorticoid receptor-mediated gene transcription in a calcium-dependent manner. Neuropharmacology 20021101
Desnitro-imidacloprid activates the extracellular signal-regulated kinase cascade via the nicotinic receptor and intracellular calcium mobilization in N1E-115 cells. Toxicology and applied pharmacology 20021101
Inhibition of PTPs by H(2)O(2) regulates the activation of distinct MAPK pathways. Free radical biology & medicine 20021015
Effect of nordihydroguaiaretic acid on intracellular Ca(2+) concentrations in hepatocytes. Toxicology in vitro : an international journal published in association with BIBRA 20021001
Genetic and pharmacological dissection of pathways involved in the angiotensin II-mediated depression of baroreflex function. FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20021001
Evidence for cadmium mobilization of intracellular calcium through a divalent cation receptor in renal distal epithelial A6 cells. Pflugers Archiv : European journal of physiology 20021001
Phospholipase C-gamma modulates epithelial tight junction permeability through hyperphosphorylation of tight junction proteins. The Journal of biological chemistry 20020920
Calcium mobilization evoked by hepatocellular swelling is linked to activation of phospholipase Cgamma. The Journal of biological chemistry 20020913
PGD(2) modulates fibroblast-mediated native collagen gel contraction. American journal of respiratory cell and molecular biology 20020901
Kit signaling inhibits the sphingomyelin-ceramide pathway through PLC gamma 1: implication in stem cell factor radioprotective effect. Blood 20020815
Dimerization and phosphorylation of thyrotropin-releasing hormone receptors are modulated by agonist stimulation. The Journal of biological chemistry 20020802
Crosstalk between ryanodine receptors and IP(3) receptors as a factor shaping spontaneous Ca(2+)-release events in rabbit portal vein myocytes. The Journal of physiology 20020801
Activation of angiotensin II type I receptor promotes protein kinase C translocation and cell proliferation in human cultured breast epithelial cells. The Journal of endocrinology 20020801
Indomethacin causes prostaglandin D(2)-like and eotaxin-like selective responses in eosinophils and basophils. The Journal of biological chemistry 20020719
Modulation of volume-sensitive chloride current by noradrenaline in rabbit portal vein myocytes. The Journal of physiology 20020715
Phospholipase C inhibitors and prostaglandins differentially regulate phosphatidylcholine synthesis in rat renal papilla. Evidence of compartmental regulation of CTP:phosphocholine cytidylyltransferase and CDP-choline:1,2-diacylglycerol cholinephosphotransferase. Biochimica et biophysica acta 20020711
Endoplasmic reticulum Ca(2+) signaling and calpains mediate renal cell death. Cell death and differentiation 20020701
Gossypol, a component in cottonseed, induced increases in cytosolic Ca2+ levels in Chang liver cells. Toxicon : official journal of the International Society on Toxinology 20020701
ATP-inhibition of M current in frog sympathetic neurons involves phospholipase C but not Ins P(3), Ca(2+), PKC, or Ras. Journal of neurophysiology 20020701
Effects of anions on ATP-induced [Ca2+], increase in NG108-15 cells. Japanese journal of pharmacology 20020701
Effect of t-butyl hydroperoxide on Ca2+ movement in PC12 pheochromocytoma cells. The Chinese journal of physiology 20020630
Mechanisms of bradykinin-induced glucagon release in clonal alpha-cells In-R1-G9: involvement of Ca(2+)-dependent and -independent pathways. Molecular and cellular endocrinology 20020628
Protease-activated receptor-2-mediated Ca2+ signaling in guinea pig tracheal epithelial cells. Life sciences 20020621
Structure-activity relationship for enhancement of paracellular permeability across Caco-2 cell monolayers by 3-alkylamido-2-alkoxypropylphosphocholines. Journal of medicinal chemistry 20020620
EBV-expressing AGS gastric carcinoma cell sublines present increased motility and invasiveness. International journal of cancer 20020610
Cloning and characterization of a phospholipase C from the C(4) plant Digitaria sanguinalis. Journal of experimental botany 20020601
Involvement of phosphoinositide turnover in tracheary element differentiation in Zinnia elegans L. cells. Planta 20020601
Selective up-regulation of phospholipase C-beta2 during granulocytic differentiation of normal and leukemic hematopoietic progenitors. Journal of leukocyte biology 20020601
Effect of purinergic agonists and antagonists on insulin secretion from INS-1 cells (insulinoma cell line) and rat pancreatic islets. Canadian journal of physiology and pharmacology 20020601
Effect of clomiphene on Ca(2+) movement in human prostate cancer cells. Life sciences 20020517
Somatostatin-induced paradoxical increase in intracellular Ca2+ concentration and insulin release in the presence of arginine vasopressin in clonal HIT-T15 beta-cells. The Biochemical journal 20020515
Nitric oxide inhibits the shedding of the glycosylphosphatidylinositol-anchored dipeptidase from porcine renal proximal tubules. The Biochemical journal 20020515
Purinergic receptor signaling at the basolateral membrane of macula densa cells. Journal of the American Society of Nephrology : JASN 20020501
A cathelicidin family of human antibacterial peptide LL-37 induces mast cell chemotaxis. Immunology 20020501
1alpha,25(OH)2D3 regulates chondrocyte matrix vesicle protein kinase C (PKC) directly via G-protein-dependent mechanisms and indirectly via incorporation of PKC during matrix vesicle biogenesis. The Journal of biological chemistry 20020405
Inositol 1,4,5-trisphosphate transduction cascade in taste reception of the fleshfly, Boettcherisca peregrina. Journal of neurobiology 20020401
Voltage independence of vasomotion in isolated irideal arterioles of the rat. The Journal of physiology 20020401
Epithelial cell-derived human beta-defensin-2 acts as a chemotaxin for mast cells through a pertussis toxin-sensitive and phospholipase C-dependent pathway. International immunology 20020401
Pharmacological analysis of nod factor-induced calcium spiking in Medicago truncatula. Evidence for the requirement of type IIA calcium pumps and phosphoinositide signaling. Plant physiology 20020401
Protective effects of protein kinase C during myocardial ischemia require activation of phosphatidyl-inositol specific phospholipase C. The Annals of thoracic surgery 20020401
Human urotensin II-induced aorta ring contractions are mediated by protein kinase C, tyrosine kinases and Rho-kinase: inhibition by somatostatin receptor antagonists. European journal of pharmacology 20020308
DARPP-32 mediates serotonergic neurotransmission in the forebrain. Proceedings of the National Academy of Sciences of the United States of America 20020305
TNF-related activation-induced cytokine (TRANCE) induces angiogenesis through the activation of Src and phospholipase C (PLC) in human endothelial cells. The Journal of biological chemistry 20020301
Thrombin-stimulated cell proliferation mediated through activation of Ras/Raf/MEK/MAPK pathway in canine cultured tracheal smooth muscle cells. Cellular signalling 20020301
ATP masks stretch activation of epithelial sodium channels in A6 distal nephron cells. American journal of physiology. Renal physiology 20020301
The effects of phospholipase C inhibition on insulin-stimulated glucose transport in skeletal muscle. Metabolism: clinical and experimental 20020301
Modulators of internal Ca2+ stores and the spontaneous electrical and contractile activity of the guinea-pig renal pelvis. British journal of pharmacology 20020301
3-phosphoinositides modulate cyclic nucleotide signaling in olfactory receptor neurons. Neuron 20020227
Phospholipase Cgamma binds alpha1beta1 integrin and modulates alpha1beta1 integrin-specific adhesion. The Journal of biological chemistry 20020215
Cdk4 and p27Kip1 play a role in PLC-gamma1-mediated mitogenic signaling pathway of 18 kDa FGF-2 in corneal endothelial cells. Molecular vision 20020208
XOD-catalyzed ROS generation mobilizes calcium from intracellular stores in mouse pancreatic acinar cells. Cellular signalling 20020201
Effect of 17beta-estradiol on intracellular Ca(2+) levels in renal tubular cells. Pharmacology 20020201
mAChRs in the grasshopper brain mediate excitation by activation of the AC/PKA and the PLC second-messenger pathways. Journal of neurophysiology 20020201
Mechanism of prostaglandin E2-stimulated heat shock protein 27 induction in osteoblast-like MC3T3-E1 cells. The Journal of endocrinology 20020201
Phospholipase D contributes to transmural pressure control of prorenin processing in juxtaglomerular cell. Hypertension (Dallas, Tex. : 1979) 20020201
Venom from the ectoparasitic wasp Nasonia vitripennis increases Na+ influx and activates phospholipase C and phospholipase A2 dependent signal transduction pathways in cultured insect cells. Toxicon : official journal of the International Society on Toxinology 20020101
Increase of [Ca(2+)](i) via activation of ATP receptors in PC-Cl3 rat thyroid cell line. Cellular signalling 20020101
Blockade of maitotoxin-induced oncotic cell death reveals zeiosis. BMC physiology 20020101
Molecular mechanisms involved in human platelet aggregation by synergistic interaction of platelet-activating factor and 5-hydroxytryptamine. Experimental & molecular medicine 20011231
Protamine augments stretch induced calcium increase in vascular endothelium. British journal of pharmacology 20011201
Mechanisms involved in alpha6beta1-integrin-mediated Ca(2+) signalling. Cellular signalling 20011201
Mechanism underlying histamine-induced intracellular Ca2+ movement in PC3 human prostate cancer cells. Pharmacological research 20011201
Production of beta-defensin-2 by human colonic epithelial cells induced by Salmonella enteritidis flagella filament structural protein. FEBS letters 20011123
Vascular smooth muscle cell spreading onto fibrinogen is regulated by calpains and phospholipase C. Biochemical and biophysical research communications 20011109
Characterisation of Rac activation in thrombin- and collagen-stimulated human blood platelets. FEBS letters 20011102
Role of PLCgamma and Ca(2+) in VEGF- and FGF-induced choroidal endothelial cell proliferation. American journal of physiology. Cell physiology 20011101
Activation of inositol 1,4,5-trisphosphate receptor is essential for the opening of mouse TRP5 channels. Molecular pharmacology 20011101
Inhibition of acetylcholine-activated K(+) currents by U73122 is mediated by the inhibition of PIP(2)-channel interaction. British journal of pharmacology 20011101
Attenuated agonist evoked vasoconstrictor responses in the perfused mesenteric vascular bed of streptozotocin diabetic rats. Experimental biology and medicine (Maywood, N.J.) 20011101
Regulation and mechanism of L-type calcium channel activation via V1a vasopressin receptor activation in cultured cortical neurons. Neurobiology of learning and memory 20011101
Bradykinin and angiotensin II-induced [Ca2+]i rise in cultured rat pituitary folliculo-stellate cells. Journal of neuroendocrinology 20011101
Second messengers in platelet aggregation evoked by serotonin and A23187, a calcium ionophore. Life sciences 20011026
Kit signaling and negative regulation of daunorubicin-induced apoptosis: role of phospholipase Cgamma. Oncogene 20011011
Stimulatory effect of phenylephrine on the secretion of beta-endorphin from rat adrenal medulla in vitro. Autonomic neuroscience : basic & clinical 20011008
Parallel metabotropic pathways in the heart of the toad, Bufo marinus. American journal of physiology. Heart and circulatory physiology 20011001
Brain-derived neurotrophic factor triggers a rapid glutamate release through increase of intracellular Ca(2+) and Na(+) in cultured cerebellar neurons. Journal of neuroscience research 20011001
Human pheochromocytomas express orexin receptor type 2 gene and display an in vitro secretory response to orexins A and B. The Journal of clinical endocrinology and metabolism 20011001
Noradrenaline and alpha-adrenergic signaling induce the hsp70 gene promoter in mollusc immune cells. Journal of cell science 20011001
Differential regulation of airway mucin gene expression and mucin secretion by extracellular nucleotide triphosphates. American journal of respiratory cell and molecular biology 20011001
Phospholipase C activation by anesthetics decreases membrane-cytoskeleton adhesion. Journal of cell science 20011001
Expression of functional receptor-coupled TRPC3 channels in DT40 triple receptor InsP3 knockout cells. The Journal of biological chemistry 20010907
cAMP potentiates H(2)O(2)-induced ERK1/2 phosphorylation without the requirement for MEK1/2 phosphorylation. Cellular signalling 20010901
Pharmacological characterization of adenosine receptors in PGT-beta mouse pineal gland tumour cells. British journal of pharmacology 20010901
Fendiline mobilizes intracellular Ca2+ in Chang liver cells. Clinical and experimental pharmacology & physiology 20010901
Differential activation of phospholipases by mitogenic EGF and neurogenic PDGF in immortalized hippocampal stem cell lines. Journal of neurochemistry 20010901
Ca2+ signaling regulated by an ATP-dependent autocrine mechanism in astrocytes. Neuroreport 20010828
CP55,940 increases intracellular Ca2+ levels in Madin-Darby canine kidney cells. Life sciences 20010817
beta-estradiol stimulation of DNA synthesis requires different PKC isoforms in HepG2 and MCF7 cells. Journal of cellular physiology 20010801
Mechanisms of bradykinin-mediated Ca(2+) signalling in canine cultured corneal epithelial cells. Cellular signalling 20010801
Anandamide-induced sleep is blocked by SR141716A, a CB1 receptor antagonist and by U73122, a phospholipase C inhibitor. Neuroreport 20010720
Miniature postsynaptic currents depend on Ca2+ released from internal stores via PLC/IP3 pathway. Neuroreport 20010720
In vivo mechanisms of vascular endothelial growth factor-mediated increased hydraulic conductivity of Rana capillaries. The Journal of physiology 20010715
Glutamate induces focal adhesion kinase tyrosine phosphorylation and actin rearrangement in heterologous mGluR1-expressing CHO cells via calcium/calmodulin signaling. Journal of neurochemistry 20010701
Local anesthetic effects on priming and activation of human neutrophils. Anesthesiology 20010701
Clomiphene, an ovulation-inducing agent, causes [Ca2+]i increases in human osteoblast-like cells. The Chinese journal of physiology 20010630
Modulation of PKCdelta tyrosine phosphorylation and activity in salivary and PC-12 cells by Src kinases. American journal of physiology. Cell physiology 20010601
Activation of P2Y but not P2X(4) nucleotide receptors causes elevation of [Ca2+]i in mammalian osteoclasts. American journal of physiology. Cell physiology 20010601
Stimulation by n6-cyclopentyladenosine of A1 adenosine receptors, coupled to galphai2 protein subunit, has a capacitative effect on human spermatozoa. Biology of reproduction 20010601
Group I mGluRs coupled to G proteins are regulated by tyrosine kinase in dopamine neurons of the rat midbrain. Journal of neurophysiology 20010601
Phosphatidylcholine-specific phospholipase C regulates activation of RAW264.7 macrophage-like cells by lipopeptide JBT3002. Journal of leukocyte biology 20010601
Endothelin- and sarafotoxin-induced receptor-mediated calcium mobilization in a clonal murine osteoblast-like cell line, MC3T3-E1/B. Bone 20010601
Receptor-mediated inhibition of G protein-coupled inwardly rectifying potassium channels involves G(alpha)q family subunits, phospholipase C, and a readily diffusible messenger. The Journal of biological chemistry 20010518
Mechanism of estrogens-induced increases in intracellular Ca(2+) in PC3 human prostate cancer cells. The Prostate 20010515
Role of the phospholipase C-inositol 1,4,5-trisphosphate pathway in calcium release-activated calcium current and capacitative calcium entry. The Journal of biological chemistry 20010511
Intracellular Ca(2+) signaling in endothelial cells by the angiogenesis inhibitors endostatin and angiostatin. American journal of physiology. Cell physiology 20010501
Sperm factor induces intracellular free calcium oscillations by stimulating the phosphoinositide pathway. Biology of reproduction 20010501
Melittin exerts multiple effects on the release of free fatty acids from L1210 cells: lack of selective activation of phospholipase A2 by melittin. Archives of biochemistry and biophysics 20010501
Effect of the antianginal drug bepridil on intracellular Ca2+ release and extracellular Ca2+ influx in human neutrophils. International immunopharmacology 20010501
Effect of fluoxetine on intracellular Ca2+ levels in bladder female transitional carcinoma (BFTC) cells. Pharmacological research 20010501
Tamoxifen-induced Ca2+ mobilization in bladder female transitional carcinoma cells. Archives of toxicology 20010501
Requirement of chondroitin sulfate/dermatan sulfate recognition in midkine-dependent migration of macrophages. Glycoconjugate journal 20010501
The Ca2+-sensing receptor activates cytosolic phospholipase A2 via a Gqalpha -dependent ERK-independent pathway. The Journal of biological chemistry 20010427
Stimulatory effect of basic fibroblast growth factor on induction of heat shock protein 27 in osteoblasts: role of protein kinase C. Archives of biochemistry and biophysics 20010415
Ca2+-induced contraction of cat esophageal circular smooth muscle cells. American journal of physiology. Cell physiology 20010401
Acetylcholine increases intracellular Ca2+ in the rat pituitary folliculostellate cells in primary culture. American journal of physiology. Endocrinology and metabolism 20010401
Mitogenic effect of oxidized low-density lipoprotein on vascular smooth muscle cells mediated by activation of Ras/Raf/MEK/MAPK pathway. British journal of pharmacology 20010401
Purinergic regulation of intracellular Ca2+ concentration of rat pituitary folliculo-stellate cells in primary culture. Journal of neuroendocrinology 20010401
Evaluation of the effects of peptide antibiotics human beta-defensins-1/-2 and LL-37 on histamine release and prostaglandin D(2) production from mast cells. European journal of immunology 20010401
NMDA-induced phosphorylation of the microtubule-associated protein MAP-2 is mediated by activation of nitric oxide synthase and MAP kinase. The European journal of neuroscience 20010401
ATP stimulates calcium-dependent glutamate release from cultured astrocytes. Journal of neurochemistry 20010401
Modulation of neutrophil phospholipase C activity and cyclic AMP levels by fMLP-OMe analogues. Cellular signalling 20010401
Mechanisms of thrombin-induced MAPK activation associated with cell proliferation in human cultured tracheal smooth muscle cells. Cellular signalling 20010401
Signal transduction pathways for activation of extracellular signal-regulated kinase by arachidonic acid in rat neutrophils. Journal of leukocyte biology 20010401
MCP-1 receptor binding affinity is up-regulated by pre-stimulation with MCP-1 in an actin polymerization-dependent manner. Journal of leukocyte biology 20010401
Synergistic effects of ATP on oxytocin-induced intracellular Ca2+ response in mouse mammary myoepithelial cells. Pflugers Archiv : European journal of physiology 20010401
Rap1 is activated by erythropoietin or interleukin-3 and is involved in regulation of beta1 integrin-mediated hematopoietic cell adhesion. The Journal of biological chemistry 20010330
Ca2+-induced Ca2+ release from the endoplasmic reticulum amplifies the Ca2+ signal mediated by activation of voltage-gated L-type Ca2+ channels in pancreatic beta-cells. The Journal of biological chemistry 20010330
Insulin activates phospholipase C-gamma1 via a PI-3 kinase dependent mechanism in 3T3-L1 adipocytes. Biochemical and biophysical research communications 20010330
Signaling pathways involved in the A and B receptor-mediated cortisol secretagogue effect of endothelins in the human adrenal cortex. International journal of molecular medicine 20010301
alpha(1D)-adrenoceptors cause endothelium-dependent vasodilatation in the rat mesenteric vascular bed. The Journal of pharmacology and experimental therapeutics 20010301
Formyl-methionyl-leucyl-phenylalanine induces prostaglandin E2 release from human amnion-derived WISH cells by phospholipase C-mediated [Ca+]i rise. Biology of reproduction 20010301
Signalling mechanisms underlying the myogenic response in human subcutaneous resistance arteries. Cardiovascular research 20010301
A role for inositol 1,4,5-trisphosphate in gravitropic signaling and the retention of cold-perceived gravistimulation of oat shoot pulvini. Plant physiology 20010301
Nutritional lipid emulsions modulate cellular signaling and activation of human neutrophils. Journal of lipid research 20010301
Neuropeptide Y Y2 receptor signalling mechanisms in the human glioblastoma cell line LN319. Peptides 20010301
ATP stimulated cyclic AMP formation in bovine chromaffin cells is enhanced by neuropeptide Y. Peptides 20010301
Effects of staurosporine, U-73122, wortmannin, 4-hydroxynonenal and sodium azide upon the release of secreted beta-amyloid precursor protein from human platelets in response to thrombin stimulation. Molecular and cellular biochemistry 20010301
Inhibition of depolarisation-evoked [(3)H]noradrenaline release from SH-SYFY human neuroblastoma cells by muscarinic (M1) receptors is not mediated by changes in [Ca(2+)]. Brain research. Molecular brain research 20010219
The transient receptor potential protein homologue TRP6 is the essential component of vascular alpha(1)-adrenoceptor-activated Ca(2+)-permeable cation channel. Circulation research 20010216
Human platelet calcium mobilisation in response to beta-amyloid (25-35): buffer dependency and unchanged response in Alzheimer's disease. Neurochemistry international 20010201
Hydrogen peroxide induces Src family tyrosine kinase-dependent activation of Xenopus eggs. Development, growth & differentiation 20010201
PTH and PTH-related peptide enhance steroid secretion from human adrenocortical cells. American journal of physiology. Endocrinology and metabolism 20010201
Purinoceptor-mediated calcium mobilization and proliferation in HaCaT keratinocytes. Journal of dermatological science 20010201
Angiotensin II provokes cesium-induced ventricular tachyarrhythmias. Cardiovascular research 20010201
Purine and pyrimidine nucleotide-sensitive phospholipase A(2) in ampulla from frog semicircular canal. American journal of physiology. Regulatory, integrative and comparative physiology 20010201
Hyperosmotic stress induces a rapid and transient increase in inositol 1,4,5-trisphosphate independent of abscisic acid in Arabidopsis cell culture. Plant & cell physiology 20010201
Nod factor-induced phosphatidic acid and diacylglycerol pyrophosphate formation: a role for phospholipase C and D in root hair deformation. The Plant journal : for cell and molecular biology 20010101
Traumatic injury of cultured astrocytes alters inositol (1,4,5)-trisphosphate-mediated signaling. Glia 20010101
Fluoxetine-induced Ca2+ signals in Madin-Darby canine kidney cells. Naunyn-Schmiedeberg's archives of pharmacology 20010101
The mechanism of maitotoxin-induced elevation of the cytosolic free calcium level in rat cerebrocortical synaptosomes. Japanese journal of pharmacology 20010101
U73122 inhibits the dephosphorylation and translocation of cofilin in activated macrophage-like U937 cells. Cellular signalling 20010101
Effect of bradykinin on cultured bovine corneal endothelial cells. Ophthalmologica. Journal international d'ophtalmologie. International journal of ophthalmology. Zeitschrift fur Augenheilkunde 20010101
[Phospholipase C negatively regulates tyrosine phosphorylation of EGF receptor in A-431 cells]. Tsitologiia 20010101
Behaviour of a somatotroph population under a growth hormone releasing peptide treatment. The Histochemical journal 20010101
Characterization of human recombinant alpha(2A)-adrenoceptors expressed in Chinese hamster lung cells using intracellular Ca(2+) changes: evidence for cross-talk between recombinant alpha(2A)- and native alpha(1)-adrenoceptors. British journal of pharmacology 20000401
Molecular and functional characterization of a novel mouse transient receptor potential protein homologue TRP7. Ca(2+)-permeable cation channel that is constitutively activated and enhanced by stimulation of G protein-coupled receptor. The Journal of biological chemistry 19990924
Direct activation of human TRPC6 and TRPC3 channels by diacylglycerol. Nature 19990121
Agonist and antagonist modulation of [35S]-GTP gamma S binding in transfected CHO cells expressing the neurotensin receptor. British journal of pharmacology 19970801
V1b and CRHR1 receptor heterodimerization mediates synergistic biological actions of vasopressin and CRH. Molecular endocrinology (Baltimore, Md.)

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