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Home > Imidazoles > 112566-20-8
112566-20-8 | Imidazo[1,2-a]pyridin-2-ol (9CI)
CAS No: 112566-20-8 Catalog No: AG00929I MDL No:MFCD09994219
Product Description
Catalog Number:
AG00929I
Chemical Name:
Imidazo[1,2-a]pyridin-2-ol (9CI)
CAS Number:
112566-20-8
Molecular Formula:
C7H6N2O
Molecular Weight:
134.1353
MDL Number:
MFCD09994219
IUPAC Name:
imidazo[1,2-a]pyridin-2-ol
InChI:
InChI=1S/C7H6N2O/c10-7-5-9-4-2-1-3-6(9)8-7/h1-5,10H
InChI Key:
WTNULKDCIHSVKN-UHFFFAOYSA-N
SMILES:
Oc1nc2n(c1)cccc2
Properties
Complexity:
129
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
1
Defined Atom Stereocenter Count:
0
Defined Bond Stereocenter Count:
0
Exact Mass:
134.048g/mol
Formal Charge:
0
Heavy Atom Count:
10
Hydrogen Bond Acceptor Count:
2
Hydrogen Bond Donor Count:
1
Isotope Atom Count:
0
Molecular Weight:
134.138g/mol
Monoisotopic Mass:
134.048g/mol
Rotatable Bond Count:
0
Topological Polar Surface Area:
37.5A^2
Undefined Atom Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
XLogP3:
1.7
Literature
| Title | Journal |
|---|---|
| Effects of ZSET1446/ST101 on cognitive deficits and amyloid β deposition in the senescence accelerated prone mouse brain. | Journal of pharmacological sciences 20120101 |
| ST101 induces a novel 17 kDa APP cleavage that precludes Aβ generation in vivo. | Annals of neurology 20110501 |
| [Neurochemical mechanisms of a novel Alzheimer's disease therapeutics on improvement of cognition and depressive behavior]. | Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 20110401 |
| Pharmacologic Treatment with GABA(B) Receptor Agonist of Methamphetamine-Induced Cognitive Impairment in Mice. | Current neuropharmacology 20110301 |
| A humanin derivative reduces amyloid beta accumulation and ameliorates memory deficit in triple transgenic mice. | PloS one 20110101 |
| Potential Antidepressant Role of Neurotransmitter CART: Implications for Mental Disorders. | Depression research and treatment 20110101 |
| A novel azaindolizinone derivative ZSET1446 (spiro[imidazo[1,2-a]pyridine-3,2-indan]-2(3H)-one) improves methamphetamine-induced impairment of recognition memory in mice by activating extracellular signal-regulated kinase 1/2. | The Journal of pharmacology and experimental therapeutics 20070201 |
| Effects of a novel cognitive enhancer, spiro[imidazo-[1,2-a]pyridine-3,2-indan]-2(3H)-one (ZSET1446), on learning impairments induced by amyloid-beta1-40 in the rat. | The Journal of pharmacology and experimental therapeutics 20060601 |
| Antiamnesic effects of azaindolizinone derivative ZSET845 on impaired learning and decreased ChAT activity induced by amyloid-beta 25-35 in the rat. | Brain research 20020802 |
| Ameliorative effects of azaindolizinone derivative ZSET845 on scopolamine-induced deficits in passive avoidance and radial-arm maze learning in the rat. | Japanese journal of pharmacology 20011101 |
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