200,000+ products from a single source!
sales@angenechem.com
Home > Other Building Blocks > 111-16-0
111-16-0 | Pimelic acid
CAS No: 111-16-0 Catalog No: AG003TSD MDL No:MFCD00004425
Product Description
Catalog Number:
AG003TSD
Chemical Name:
Pimelic acid
CAS Number:
111-16-0
Molecular Formula:
C7H12O4
Molecular Weight:
160.1678
MDL Number:
MFCD00004425
IUPAC Name:
heptanedioic acid
InChI:
InChI=1S/C7H12O4/c8-6(9)4-2-1-3-5-7(10)11/h1-5H2,(H,8,9)(H,10,11)
InChI Key:
WLJVNTCWHIRURA-UHFFFAOYSA-N
SMILES:
OC(=O)CCCCCC(=O)O
EC Number:
203-840-8
UNII:
BZQ96WX25F
NSC Number:
30112
Properties
Complexity:
125
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
1
Defined Atom Stereocenter Count:
0
Defined Bond Stereocenter Count:
0
Exact Mass:
160.074g/mol
Formal Charge:
0
Heavy Atom Count:
11
Hydrogen Bond Acceptor Count:
4
Hydrogen Bond Donor Count:
2
Isotope Atom Count:
0
Molecular Weight:
160.169g/mol
Monoisotopic Mass:
160.074g/mol
Rotatable Bond Count:
6
Topological Polar Surface Area:
74.6A^2
Undefined Atom Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
XLogP3:
0.5
Literature
| Title | Journal |
|---|---|
| A new synthetic HDAC inhibitor, MHY218, induces apoptosis or autophagy-related cell death in tamoxifen-resistant MCF-7 breast cancer cells. | Investigational new drugs 20121001 |
| Lipid profiling of the Arabidopsis hypersensitive response reveals specific lipid peroxidation and fragmentation processes: biogenesis of pimelic and azelaic acid. | Plant physiology 20120901 |
| Development of controlled release formulations of imidacloprid employing novel nano-ranged amphiphilic polymers. | Journal of environmental science and health. Part. B, Pesticides, food contaminants, and agricultural wastes 20120101 |
| Metabolomics-based study of clinical and animal plasma samples in coronary heart disease with blood stasis syndrome. | Evidence-based complementary and alternative medicine : eCAM 20120101 |
| Tandem synthesis of alternating polyesters from renewable resources. | Nature communications 20111213 |
| Contributions of the peroxisome and β-oxidation cycle to biotin synthesis in fungi. | The Journal of biological chemistry 20111209 |
| Differential interaction of dicarboxylates with human sodium-dicarboxylate cotransporter 3 and organic anion transporters 1 and 3. | American journal of physiology. Renal physiology 20111101 |
| UPLC-MS-based urine metabolomics reveals indole-3-lactic acid and phenyllactic acid as conserved biomarkers for alcohol-induced liver disease in the Ppara-null mouse model. | Journal of proteome research 20110902 |
| Two dimensional self-assembly of bis-acylureas having various functional end groups. | Journal of colloid and interface science 20110715 |
| Pimelic acid-urea (1/2). | Acta crystallographica. Section E, Structure reports online 20110701 |
| Synthesis of the α,ω-dicarboxylic acid precursor of biotin by the canonical fatty acid biosynthetic pathway. | Current opinion in chemical biology 20110601 |
| Closing in on complete pathways of biotin biosynthesis. | Molecular bioSystems 20110601 |
| Poly[hexa-aqua-bis-(μ(3)-hepta-nedioato-κO:O':O'')dimagnesium]. | Acta crystallographica. Section E, Structure reports online 20110601 |
| Functional characterization of a gene cluster involved in gentisate catabolism in Rhodococcus sp. strain NCIMB 12038. | Applied microbiology and biotechnology 20110401 |
| Metabolite cross-feeding enhances virulence in a model polymicrobial infection. | PLoS pathogens 20110301 |
| Bacterial syntenies: an exact approach with gene quorum. | BMC bioinformatics 20110101 |
| Importance of the long-chain fatty acid beta-hydroxylating cytochrome P450 enzyme YbdT for lipopeptide biosynthesis in Bacillus subtilis strain OKB105. | International journal of molecular sciences 20110101 |
| Environment sensing and response mediated by ABC transporters. | BMC genomics 20110101 |
| In vivo and in silico determination of essential genes of Campylobacter jejuni. | BMC genomics 20110101 |
| Metabolomics of oxidative stress in recent studies of endogenous and exogenously administered intermediate metabolites. | International journal of molecular sciences 20110101 |
| Evaluating the effects of crystallinity in new biocompatible polyester nanocarriers on drug release behavior. | International journal of nanomedicine 20110101 |
| Degradation of a model naphthenic acid, cyclohexanoic acid, by vacuum UV (172 nm) and UV (254 nm)/H2O2. | The journal of physical chemistry. A 20101118 |
| Biotin synthesis begins by hijacking the fatty acid synthetic pathway. | Nature chemical biology 20100901 |
| Identification of noninvasive biomarkers for alcohol-induced liver disease using urinary metabolomics and the Ppara-null mouse. | Journal of proteome research 20100806 |
| Anticancer effects of the MHY218 novel hydroxamic acid-derived histone deacetylase inhibitor in human ovarian cancer cells. | International journal of oncology 20100801 |
| Selectivity in a barren landscape: the P450(BioI)-ACP complex. | Biochemical Society transactions 20100801 |
| Aerosol volatility and enthalpy of sublimation of carboxylic acids. | The journal of physical chemistry. A 20100408 |
| Two new pimelic diphenylamide HDAC inhibitors induce sustained frataxin upregulation in cells from Friedreich's ataxia patients and in a mouse model. | PloS one 20100101 |
| Analysis of gene evolution and metabolic pathways using the Candida Gene Order Browser. | BMC genomics 20100101 |
| The complete genome sequence of Cupriavidus metallidurans strain CH34, a master survivalist in harsh and anthropogenic environments. | PloS one 20100101 |
| A genomic perspective on the potential of Actinobacillus succinogenes for industrial succinate production. | BMC genomics 20100101 |
| Chemical probes identify a role for histone deacetylase 3 in Friedreich's ataxia gene silencing. | Chemistry & biology 20090925 |
| Radiation metabolomics. 3. Biomarker discovery in the urine of gamma-irradiated rats using a simplified metabolomics protocol of gas chromatography-mass spectrometry combined with random forests machine learning algorithm. | Radiation research 20090801 |
| Metabonomics approach to understanding acute and chronic stress in rat models. | Journal of proteome research 20090501 |
| Involvement of an alternatively spliced mitochondrial oxodicarboxylate carrier in adipogenesis in 3T3-L1 cells. | Journal of biomedical science 20090101 |
| Synthesis, Binding and Fluorescence Studies of Bis-2-amidopyrrole Receptors for Bis-carboxylate Anions. | Sensors (Basel, Switzerland) 20090101 |
| Pimelic diphenylamide 106 is a slow, tight-binding inhibitor of class I histone deacetylases. | The Journal of biological chemistry 20081219 |
| Structure of bacterial glutathione-S-transferase maleyl pyruvate isomerase and implications for mechanism of isomerisation. | Journal of molecular biology 20081205 |
| Use of benzoate as an electron acceptor by Syntrophus aciditrophicus grown in pure culture with crotonate. | Environmental microbiology 20081201 |
| Spontaneous reaction silencing in metabolic optimization. | PLoS computational biology 20081201 |
| Synthesis and solution structure of 3,5-dioxopimelic acid diesters--stable 1,3,5,7-tetracarbonyl derivatives. | Organic & biomolecular chemistry 20080907 |
| (Heptanedioato-κO,O')bis-(1,10-phenanthroline-κN,N')zinc(II) hexa-hydrate. | Acta crystallographica. Section E, Structure reports online 20080401 |
| Conformationally constrained diketopimelic acid analogues as inhibitors of dihydrodipicolinate synthase. | Bioorganic & medicinal chemistry letters 20080115 |
| Crystal structures and site-directed mutagenesis of a mycothiol-dependent enzyme reveal a novel folding and molecular basis for mycothiol-mediated maleylpyruvate isomerization. | The Journal of biological chemistry 20070601 |
| Molecular model for host–guest interaction of tetraamino-tert-butylthiacalix[4]arene and tetraamino-tert-butylcalix[4]arene receptors with carboxylate and dicarboxylate guests: an ONIOM study. | Journal of molecular modeling 20070101 |
| Complete gene expression profiling of Saccharopolyspora erythraea using GeneChip DNA microarrays. | Microbial cell factories 20070101 |
| A dinuclear lanthanide complex for the recognition of bis(carboxylates): formation of terbium(III) luminescent self-assembly ternary complexes in aqueous solution. | Inorganic chemistry 20061113 |
| Histone deacetylase inhibitors reverse gene silencing in Friedreich's ataxia. | Nature chemical biology 20061001 |
| Biological significance and development of practical synthesis of biotin. | Medicinal research reviews 20060701 |
| The gene ncgl2918 encodes a novel maleylpyruvate isomerase that needs mycothiol as cofactor and links mycothiol biosynthesis and gentisate assimilation in Corynebacterium glutamicum. | The Journal of biological chemistry 20060421 |
| Integration of metabolome data with metabolic networks reveals reporter reactions. | Molecular systems biology 20060101 |
| Synthesis, Superoxide Dismutase Mimetic and Anticancer Activities of Metal Complexes of 2,2-Dimethylpentanedioic Acid(2dmepdaH(2)) and 3,3-Dimethylpentanedioic acid(3dmepdaH(2)): X-Ray Crystal Structures of [Cu(3dmepda)(bipy)](2). 6H(2)O and [Cu(2dmepda)(bipy)(EtOH)](2). 4EtOH (bipy = 2,2'Bipyridine). | Bioinorganic chemistry and applications 20060101 |
| Chemically synthesized pathogen-associated molecular patterns increase the expression of peptidoglycan recognition proteins via toll-like receptors, NOD1 and NOD2 in human oral epithelial cells. | Cellular microbiology 20050501 |
| The pimFABCDE operon from Rhodopseudomonas palustris mediates dicarboxylic acid degradation and participates in anaerobic benzoate degradation. | Microbiology (Reading, England) 20050301 |
| Spin-labelled vacuolar-ATPase inhibitors in lipid membranes. | Biochimica et biophysica acta 20041011 |
| Carbon-carbon bond cleavage by cytochrome p450(BioI)(CYP107H1). | Chemical communications (Cambridge, England) 20040107 |
| Viscosity B-coefficients and activation parameters for viscous flow of a solution of heptanedioic acid in aqueous sucrose solution. | Carbohydrate research 20031121 |
| X-ray studies on crystalline complexes involving amino acids and peptides. XLI. Commonalities in aggregation and conformation revealed by the crystal structures of the pimelic acid complexes of L-arginine and DL-lysine. | Acta crystallographica. Section B, Structural science 20031001 |
| Structural phases of hexamethylenetetramine-pimelic acid (1/1): a unified description based on a stacking model. | Acta crystallographica. Section B, Structural science 20030801 |
| Alicycliphilus denitrificans gen. nov., sp. nov., a cyclohexanol-degrading, nitrate-reducing beta-proteobacterium. | International journal of systematic and evolutionary microbiology 20030101 |
| Acyl group specificity at the active site of tetrahydridipicolinate N-succinyltransferase. | Protein science : a publication of the Protein Society 20020401 |
| Characterization of the initial steps in the reductive dehalogenation catalyzed by tetrachlorohydroquinone dehalogenase. | Biochemistry 20020129 |
| Selective nucleation and discovery of organic polymorphs through epitaxy with single crystal substrates. | Journal of the American Chemical Society 20011107 |
| Infrared spectra of the hydrogen bond in pimelic acid crystals: polarization and temperature effects. | Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20011001 |
| Isotope-tagged cross-linking reagents. A new tool in mass spectrometric protein interaction analysis. | Analytical chemistry 20010501 |
| Identification of the human mitochondrial oxodicarboxylate carrier. Bacterial expression, reconstitution, functional characterization, tissue distribution, and chromosomal location. | The Journal of biological chemistry 20010316 |
| nag genes of Ralstonia (formerly Pseudomonas) sp. strain U2 encoding enzymes for gentisate catabolism. | Journal of bacteriology 20010101 |
| Biochemical and genetic characterization of a gentisate 1, 2-dioxygenase from Sphingomonas sp. strain RW5. | Journal of bacteriology 19980801 |
| Anaerobic degradation of pimelate by newly isolated denitrifying bacteria. | Microbiology (Reading, England) 19940201 |
| Bacterial metabolism of 5-aminosalicylic acid: enzymic conversion to L-malate, pyruvate and ammonia. | Journal of general microbiology 19930501 |
| Inhibition of HIV-1 proteinase by non-peptide carboxylates. | Biochemical and biophysical research communications 19910415 |
| Streptomyces DD-carboxypeptidases as transpeptidases. The specificity for amino compounds acting as carboxyl acceptors. | The Biochemical journal 19730401 |
| Isolation and characterization of uridine diphosphate-N-glycolylmuramyl-L-alanyl-gamma-D-glutamyl-meso-alpha,alpha'-diaminopimelic acid from Mycobacterium tuberculosis. | Biochemical and biophysical research communications 19700408 |
Related Products
Featured Products
© 2019 Angene International Limited. All rights Reserved.