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106-65-0 | Dimethyl Succinate
CAS No: 106-65-0 Catalog No: AG0034RC MDL No:MFCD00008466
Product Description
Catalog Number:
AG0034RC
Chemical Name:
Dimethyl Succinate
CAS Number:
106-65-0
Molecular Formula:
C6H10O4
Molecular Weight:
146.1412
MDL Number:
MFCD00008466
IUPAC Name:
dimethyl butanedioate
InChI:
InChI=1S/C6H10O4/c1-9-5(7)3-4-6(8)10-2/h3-4H2,1-2H3
InChI Key:
MUXOBHXGJLMRAB-UHFFFAOYSA-N
SMILES:
COC(=O)CCC(=O)OC
EC Number:
203-419-9
UNII:
914I2127JR
NSC Number:
52209
FEMA Number:
2396
UN Number:
1993
Properties
Complexity:
114
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
1
Defined Atom Stereocenter Count:
0
Defined Bond Stereocenter Count:
0
Exact Mass:
146.058g/mol
Formal Charge:
0
Heavy Atom Count:
10
Hydrogen Bond Acceptor Count:
4
Hydrogen Bond Donor Count:
0
Isotope Atom Count:
0
Molecular Weight:
146.142g/mol
Monoisotopic Mass:
146.058g/mol
Rotatable Bond Count:
5
Topological Polar Surface Area:
52.6A^2
Undefined Atom Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
XLogP3:
0.4
Literature
| Title | Journal |
|---|---|
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| Antimicrobial hydantoin-containing polyesters. | Macromolecular bioscience 20120801 |
| Reactive oxygen species stimulate insulin secretion in rat pancreatic islets: studies using mono-oleoyl-glycerol. | PloS one 20120101 |
| Analysis of volatile organic compounds released from human lung cancer cells and from the urine of tumor-bearing mice. | Cancer cell international 20120101 |
| Investigation of mitochondrial dysfunction by sequential microplate-based respiration measurements from intact and permeabilized neurons. | PloS one 20120101 |
| Dopamine induced neurodegeneration in a PINK1 model of Parkinson's disease. | PloS one 20120101 |
| Metformin and phenethyl isothiocyanate combined treatment in vitro is cytotoxic to ovarian cancer cultures. | Journal of ovarian research 20120101 |
| Metformin activates AMP-activated protein kinase in primary human hepatocytes by decreasing cellular energy status. | Diabetologia 20111201 |
| Glucocorticoid-induced cell death is mediated through reduced glucose metabolism in lymphoid leukemia cells. | Blood cancer journal 20110701 |
| Bioenergetic consequences of PINK1 mutations in Parkinson disease. | PloS one 20110101 |
| Chemical synthesis of fully biomass-based poly(butylene succinate) from inedible-biomass-based furfural and evaluation of its biomass carbon ratio. | Biomacromolecules 20101011 |
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| Complete genome sequence of Gordonia bronchialis type strain (3410). | Standards in genomic sciences 20100227 |
| Glucose sensing in the pancreatic beta cell: a computational systems analysis. | Theoretical biology & medical modelling 20100101 |
| Synthesis and activity of N-oxalylglycine and its derivatives as Jumonji C-domain-containing histone lysine demethylase inhibitors. | Bioorganic & medicinal chemistry letters 20090515 |
| Solvation of dimethyl succinate in a sodium hydroxide aqueous solution. A computational study. | The journal of physical chemistry. B 20090507 |
| PINK1-associated Parkinson's disease is caused by neuronal vulnerability to calcium-induced cell death. | Molecular cell 20090313 |
| Influence of Honey on the Suppression of Human Low Density Lipoprotein (LDL) Peroxidation (In vitro). | Evidence-based complementary and alternative medicine : eCAM 20090301 |
| Impaired anaplerosis and insulin secretion in insulinoma cells caused by small interfering RNA-mediated suppression of pyruvate carboxylase. | The Journal of biological chemistry 20081017 |
| Metabolomic and mass isotopomer analysis of liver gluconeogenesis and citric acid cycle. I. Interrelation between gluconeogenesis and cataplerosis; formation of methoxamates from aminooxyacetate and ketoacids. | The Journal of biological chemistry 20080808 |
| Mechanisms underlying the loss of mitochondrial membrane potential in glutamate excitotoxicity. | Biochimica et biophysica acta 20080101 |
| Hypoxia stabilizes type 2 deiodinase activity in rat astrocytes. | Endocrinology 20071001 |
| Ca2+, NAD(P)H and membrane potential changes in pancreatic beta-cells by methyl succinate: comparison with glucose. | The Biochemical journal 20070401 |
| Methyl succinate antagonises biguanide-induced AMPK-activation and death of pancreatic beta-cells through restoration of mitochondrial electron transfer. | British journal of pharmacology 20070401 |
| Synthesis of 1,4-diphenylbutadiene derivatives: novel inducer of tissue-type plasminogen activator (t-PA) in cultured bovine endothelial cells. | Chemical & pharmaceutical bulletin 20061201 |
| A Kir6.2 mutation causing neonatal diabetes impairs electrical activity and insulin secretion from INS-1 beta-cells. | Diabetes 20061101 |
| Microsphere-based protease assays and screening application for lethal factor and factor Xa. | Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501 |
| Process model and economic analysis of itaconic acid production from dimethyl succinate and formaldehyde. | Bioresource technology 20060101 |
| Bench-to-bedside review: potential strategies to protect or reverse mitochondrial dysfunction in sepsis-induced organ failure. | Critical care (London, England) 20060101 |
| The role of an astrocytic NADPH oxidase in the neurotoxicity of amyloid beta peptides. | Philosophical transactions of the Royal Society of London. Series B, Biological sciences 20051229 |
| Degradation of malathion, in aqueous extracts of asparagus (Asparagus officinalis). | Journal of agricultural and food chemistry 20040922 |
| Similar effects of succinic acid dimethyl ester and glucose on islet calcium oscillations and insulin release. | Biochemical pharmacology 20040301 |
| (E)-2-(2-adamantylidene)-3-(1-ferrocenylethylidene)succinic anhydride. | Acta crystallographica. Section C, Crystal structure communications 20030201 |
| Synthesis and characterization of poly(butylene succinate-co-butylene malate): a new biodegradable copolyester bearing hydroxyl pendant groups. | Biomacromolecules 20030101 |
| Differences between mouse and rat pancreatic islets: succinate responsiveness, malic enzyme, and anaplerosis. | American journal of physiology. Endocrinology and metabolism 20020801 |
| Resistance of succinic acid dimethyl ester insulinotropic action to exendin (9-39) amide. | Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme 20020101 |
| Synergistic insulinotropic effects of succinic acid dimethyl ester and exendin-4 in anaesthetized rats. | International journal of molecular medicine 20010901 |
| Isolation of high-malate-producing sake yeasts from low-maltose-assimilating mutants. | Journal of bioscience and bioengineering 20010101 |
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