CAS 105404-65-7 | Ethyl 1-cyclopropyl-6-fluoro-4-oxo-7-(piperazin-1-yl)-1,4-dihydroquinoline-3-carboxylate | CAS Number 105404-65-7

200,000+ products from a single source!

sales@angenechem.com

Product Categories

Home > Carboxes > 105404-65-7

105404-65-7 | Ethyl 1-cyclopropyl-6-fluoro-4-oxo-7-(piperazin-1-yl)-1,4-dihydroquinoline-3-carboxylate

CAS No: 105404-65-7 Catalog No: AG0039XG MDL No:MFCD24038928

Product Description

Catalog Number:

AG0039XG

Chemical Name:

Ethyl 1-cyclopropyl-6-fluoro-4-oxo-7-(piperazin-1-yl)-1,4-dihydroquinoline-3-carboxylate

CAS Number:

105404-65-7

Molecular Formula:

C19H22FN3O3

Molecular Weight:

359.3947

MDL Number:

MFCD24038928

IUPAC Name:

ethyl 1-cyclopropyl-6-fluoro-4-oxo-7-piperazin-1-ylquinoline-3-carboxylate

InChI:

InChI=1S/C19H22FN3O3/c1-2-26-19(25)14-11-23(12-3-4-12)16-10-17(22-7-5-21-6-8-22)15(20)9-13(16)18(14)24/h9-12,21H,2-8H2,1H3

InChI Key:

CIADNHRRTXHFIO-UHFFFAOYSA-N

SMILES:

CCOC(=O)c1cn(C2CC2)c2c(c1=O)cc(c(c2)N1CCNCC1)F

Properties

Complexity:

601

Compound Is Canonicalized:

Yes

Covalently-Bonded Unit Count:

Defined Atom Stereocenter Count:

Defined Bond Stereocenter Count:

Exact Mass:

359.165g/mol

Formal Charge:

Heavy Atom Count:

Hydrogen Bond Acceptor Count:

Hydrogen Bond Donor Count:

Isotope Atom Count:

Molecular Weight:

359.401g/mol

Monoisotopic Mass:

359.165g/mol

Rotatable Bond Count:

Topological Polar Surface Area:

61.9A^2

Undefined Atom Stereocenter Count:

Undefined Bond Stereocenter Count:

XLogP3:

1.3

Literature

Title	Journal
Discovery of novel inhibitors of the NorA multidrug transporter of Staphylococcus aureus.	Journal of medicinal chemistry 20110113
From 6-aminoquinolone antibacterials to 6-amino-7-thiopyranopyridinylquinolone ethyl esters as inhibitors of Staphylococcus aureus multidrug efflux pumps.	Journal of medicinal chemistry 20100610
Enhancement of the antimalarial activity of ciprofloxacin using a double prodrug/bioorganometallic approach.	Journal of medicinal chemistry 20091224