200,000+ products from a single source!
sales@angenechem.com
Home > Other Building Blocks > 104504-45-2
104504-45-2 | H-Bpa-OH H-Phe(4-Bz);-OH
CAS No: 104504-45-2 Catalog No: AG003KSN MDL No:MFCD00238102
Product Description
Catalog Number:
AG003KSN
Chemical Name:
H-Bpa-OH H-Phe(4-Bz);-OH
CAS Number:
104504-45-2
Molecular Formula:
C16H15NO3
Molecular Weight:
269.2952
MDL Number:
MFCD00238102
IUPAC Name:
(2S)-2-amino-3-(4-benzoylphenyl)propanoic acid
InChI:
InChI=1S/C16H15NO3/c17-14(16(19)20)10-11-6-8-13(9-7-11)15(18)12-4-2-1-3-5-12/h1-9,14H,10,17H2,(H,19,20)/t14-/m0/s1
InChI Key:
TVIDEEHSOPHZBR-AWEZNQCLSA-N
SMILES:
N[C@H](C(=O)O)Cc1ccc(cc1)C(=O)c1ccccc1
UNII:
9RU6KQ9WYD
Properties
Complexity:
342
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
1
Defined Atom Stereocenter Count:
1
Defined Bond Stereocenter Count:
0
Exact Mass:
269.105g/mol
Formal Charge:
0
Heavy Atom Count:
20
Hydrogen Bond Acceptor Count:
4
Hydrogen Bond Donor Count:
2
Isotope Atom Count:
0
Molecular Weight:
269.3g/mol
Monoisotopic Mass:
269.105g/mol
Rotatable Bond Count:
5
Topological Polar Surface Area:
80.4A^2
Undefined Atom Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
XLogP3:
0.2
Literature
| Title | Journal |
|---|---|
| Structure-activity and immunochemical data provide evidence of developmental- and tissue-specific myosuppressin signaling. | Peptides 20120801 |
| Probing the conformation of the ISWI ATPase domain with genetically encoded photoreactive crosslinkers and mass spectrometry. | Molecular & cellular proteomics : MCP 20120401 |
| Wide-range protein photo-crosslinking achieved by a genetically encoded N(ε)-(benzyloxycarbonyl)lysine derivative with a diazirinyl moiety. | Molecular bioSystems 20120401 |
| Caught in the act: covalent cross-linking captures activator-coactivator interactions in vivo. | ACS chemical biology 20111216 |
| Photoaffinity labeling of Ras converting enzyme using peptide substrates that incorporate benzoylphenylalanine (Bpa) residues: improved labeling and structural implications. | Bioorganic & medicinal chemistry 20111215 |
| Genetically encoding unnatural amino acids in neural stem cells and optically reporting voltage-sensitive domain changes in differentiated neurons. | Stem cells (Dayton, Ohio) 20110801 |
| Refinement of glucagon-like peptide 1 docking to its intact receptor using mid-region photolabile probes and molecular modeling. | The Journal of biological chemistry 20110506 |
| Mapping the ligand-binding site on a G protein-coupled receptor (GPCR) using genetically encoded photocrosslinkers. | Biochemistry 20110503 |
| Synthetic approach to stop-codon scanning mutagenesis. | Journal of the American Chemical Society 20110427 |
| Mapping of the SecA·SecY and SecA·SecG interfaces by site-directed in vivo photocross-linking. | The Journal of biological chemistry 20110408 |
| Identification by photoaffinity labeling of the extracellular N-terminal domain of PAC1 receptor as the major binding site for PACAP. | Biochimie 20110401 |
| Crystallographic study of a site-specifically cross-linked protein complex with a genetically incorporated photoreactive amino acid. | Biochemistry 20110118 |
| Temperature dependent photolabeling of the human angiotensin II type 1 receptor reveals insights into its conformational landscape and its activation mechanism. | Biochemical pharmacology 20101001 |
| Condensed E. coli cultures for highly efficient production of proteins containing unnatural amino acids. | Bioorganic & medicinal chemistry letters 20101001 |
| A new tool for photoaffinity labeling studies: a partially constrained, benzophenone based, alpha-amino acid. | Organic & biomolecular chemistry 20100721 |
| The amino-terminus of angiotensin II contacts several ectodomains of the angiotensin II receptor AT1. | Journal of medicinal chemistry 20100311 |
| Genetic incorporation of unnatural amino acids into proteins in Mycobacterium tuberculosis. | PloS one 20100101 |
| Biology by design: from top to bottom and back. | Journal of biomedicine & biotechnology 20100101 |
| Photolabeling identifies transmembrane domain 4 of CXCR4 as a T140 binding site. | Biochemical pharmacology 20091201 |
| Impact of nonnatural amino acid mutagenesis on the in vivo function and binding modes of a transcriptional activator. | Journal of the American Chemical Society 20091014 |
| Protein-DNA photo-crosslinking with a genetically encoded benzophenone-containing amino acid. | Bioorganic & medicinal chemistry letters 20090901 |
| FTIR analysis of GPCR activation using azido probes. | Nature chemical biology 20090601 |
| Incorporation of the unnatural amino acid p-benzoyl-L-phenylalanine (Bpa) into a G protein-coupled receptor in its native context. | Advances in experimental medicine and biology 20090101 |
| Residue 17 of sauvagine cross-links to the first transmembrane domain of corticotropin-releasing factor receptor 1 (CRFR1). | The Journal of biological chemistry 20081219 |
| Identification of ETA and ETB binding domains using ET-derived photoprobes. | Biochimie 20080601 |
| Unnatural amino acid replacement in a yeast G protein-coupled receptor in its native environment. | Biochemistry 20080520 |
| Mapping ligand-receptor interfaces: approaching the resolution limit of benzophenone-based photoaffinity scanning. | Chemical biology & drug design 20080401 |
| Site-specific incorporation of keto amino acids into functional G protein-coupled receptors using unnatural amino acid mutagenesis. | The Journal of biological chemistry 20080118 |
| Photolabelling the urotensin II receptor reveals distinct agonist- and partial-agonist-binding sites. | The Biochemical journal 20070215 |
| Structural basis for the recognition of para-benzoyl-L-phenylalanine by evolved aminoacyl-tRNA synthetases. | Angewandte Chemie (International ed. in English) 20070101 |
| Site-specific incorporation of non-natural amino acids into proteins in mammalian cells with an expanded genetic code. | Nature protocols 20060101 |
| Photoaffinity cross-linking of the corticotropin-releasing factor receptor type 1 with photoreactive urocortin analogues. | Biochemistry 20051129 |
| Differential spatial approximation between cholecystokinin residue 30 and receptor residues in active and inactive conformations. | Molecular pharmacology 20050601 |
| Differential docking of high-affinity peptide ligands to type A and B cholecystokinin receptors demonstrated by photoaffinity labeling. | Biochemistry 20050503 |
| Photo-cross-linking interacting proteins with a genetically encoded benzophenone. | Nature methods 20050501 |
| Protein photo-cross-linking in mammalian cells by site-specific incorporation of a photoreactive amino acid. | Nature methods 20050301 |
| Analysis of ligand-receptor cross-linked fragments by mass spectrometry. | The journal of peptide research : official journal of the American Peptide Society 20050301 |
| Identification of ligand binding regions of the Saccharomyces cerevisiae alpha-factor pheromone receptor by photoaffinity cross-linking. | Biochemistry 20041019 |
| Identification of a binding domain of the endothelin-B receptor using a selective IRL-1620-derived photoprobe. | Biochemistry 20040914 |
| Benzophenone photophore flexibility and proximity: molecular and crystal-state structure of a Bpa-containing trichogin dodecapeptide analogue. | Chembiochem : a European journal of chemical biology 20040402 |
| Identification of a contact site for residue 19 of parathyroid hormone (PTH) and PTH-related protein analogs in transmembrane domain two of the type 1 PTH receptor. | Molecular endocrinology (Baltimore, Md.) 20031201 |
| Synthesis of chemotactic peptide analogs with a photoaffinity cross-linker as new probes for analysis of receptor-ligand interaction. | Protein and peptide letters 20030401 |
| Photolabelling the rat urotensin II/GPR14 receptor identifies a ligand-binding site in the fourth transmembrane domain. | The Biochemical journal 20030315 |
| Identification of a contact region between the tridecapeptide alpha-factor mating pheromone of Saccharomyces cerevisiae and its G protein-coupled receptor by photoaffinity labeling. | Biochemistry 20020514 |
| Methionine proximity assay, a novel method for exploring peptide ligand-receptor interaction. | Journal of receptor and signal transduction research 20020101 |
| Identification of determinants of inverse agonism in a constitutively active parathyroid hormone/parathyroid hormone-related peptide receptor by photoaffinity cross-linking and mutational analysis. | The Journal of biological chemistry 20011116 |
| Multiple sites of contact between the carboxyl-terminal binding domain of PTHrP-(1--36) analogs and the amino-terminal extracellular domain of the PTH/PTHrP receptor identified by photoaffinity cross-linking. | The Journal of biological chemistry 20010803 |
| Molecular characterization of the substance P*neurokinin-1 receptor complex: development of an experimentally based model. | The Journal of biological chemistry 20010622 |
| Tritiated photoactivatable analogs of the native human thrombin receptor (PAR-1) agonist peptide, SFLLRN-NH2. | The journal of peptide research : official journal of the American Peptide Society 20010601 |
| Photoaffinity labeling of mutant neurokinin-1 receptors reveals additional structural features of the substance P/NK-1 receptor complex. | Biochemistry 20010227 |
| Mapping tertiary interactions in protein folding reactions: a novel mass spectrometry- and chemical synthesis-based approach. | Fresenius' journal of analytical chemistry 20010201 |
Related Products
Featured Products
© 2019 Angene International Limited. All rights Reserved.