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103-81-1 | 2-Phenylacetamide
CAS No: 103-81-1 Catalog No: AG0032A4 MDL No:MFCD00059193
Product Description
Catalog Number:
AG0032A4
Chemical Name:
2-Phenylacetamide
CAS Number:
103-81-1
Molecular Formula:
C8H9NO
Molecular Weight:
135.1632
MDL Number:
MFCD00059193
IUPAC Name:
2-phenylacetamide
InChI:
InChI=1S/C8H9NO/c9-8(10)6-7-4-2-1-3-5-7/h1-5H,6H2,(H2,9,10)
InChI Key:
LSBDFXRDZJMBSC-UHFFFAOYSA-N
SMILES:
NC(=O)Cc1ccccc1
EC Number:
203-147-0
UNII:
5R219M9TJF
NSC Number:
1877
Properties
Complexity:
116
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
1
Defined Atom Stereocenter Count:
0
Defined Bond Stereocenter Count:
0
Exact Mass:
135.068g/mol
Formal Charge:
0
Heavy Atom Count:
10
Hydrogen Bond Acceptor Count:
1
Hydrogen Bond Donor Count:
1
Isotope Atom Count:
0
Molecular Weight:
135.166g/mol
Monoisotopic Mass:
135.068g/mol
Rotatable Bond Count:
2
Topological Polar Surface Area:
43.1A^2
Undefined Atom Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
XLogP3:
0.5
Literature
| Title | Journal |
|---|---|
| Caffeic acid phenethyl ester and its amide analogue are potent inhibitors of leukotriene biosynthesis in human polymorphonuclear leukocytes. | PloS one 20120101 |
| Comparative pharmacology of cholecystokinin induced activation of cultured vagal afferent neurons from rats and mice. | PloS one 20120101 |
| N,N'-Dibenzyl-N,N'-dimethyl-N''-(2-phenyl-acet-yl)phospho-ric triamide. | Acta crystallographica. Section E, Structure reports online 20111201 |
| Spilanthes acmella ethanolic flower extract: LC-MS alkylamide profiling and its effects on sexual behavior in male rats. | Phytomedicine : international journal of phytotherapy and phytopharmacology 20111015 |
| NRPS substrate promiscuity diversifies the xenematides. | Organic letters 20111007 |
| Optimisation of the anti-Trypanosoma brucei activity of the opioid agonist U50488. | ChemMedChem 20111004 |
| Phenylalanine induces Burkholderia cenocepacia phenylacetic acid catabolism through degradation to phenylacetyl-CoA in synthetic cystic fibrosis sputum medium. | Microbial pathogenesis 20110901 |
| Gram-positive marine bacteria as a potential resource for the discovery of quorum sensing inhibitors. | Marine biotechnology (New York, N.Y.) 20110801 |
| Structure-based design, synthesis, and antifungal activity of new triazole derivatives. | Chemical biology & drug design 20110801 |
| Extracellular loop 2 of the free fatty acid receptor 2 mediates allosterism of a phenylacetamide ago-allosteric modulator. | Molecular pharmacology 20110701 |
| Isolation and characterization of atropisomers of seven-membered-ring benzolactams. | The Journal of organic chemistry 20110617 |
| Valine and phenylalanine as precursors in the biosynthesis of alkamides in Acmella radicans. | Natural product communications 20110601 |
| Efficacy of Advanced Odomos repellent cream (N, N-diethyl-benzamide) against mosquito vectors. | The Indian journal of medical research 20110401 |
| Chemical composition and antioxidant properties of extracts of fresh fruiting bodies of Pleurotus sajor-caju (Fr.) Singer. | Journal of agricultural and food chemistry 20110323 |
| Synthesis of new 1,3-oxazolyl-7-chloroquinazolin-4(3H)ones and evaluation of their antimicrobial activities. | Acta poloniae pharmaceutica 20110101 |
| SCFAs induce mouse neutrophil chemotaxis through the GPR43 receptor. | PloS one 20110101 |
| LC-MS profiling of N-alkylamides in Spilanthes acmella extract and the transmucosal behaviour of its main bio-active spilanthol. | Journal of pharmaceutical and biomedical analysis 20101102 |
| 2,3-Disubstituted acrylamides as potent glucokinase activators. | Bioorganic & medicinal chemistry letters 20101001 |
| Structural characterization of the Hepatitis C Virus NS3 protease from genotype 3a: the basis of the genotype 1b vs. 3a inhibitor potency shift. | Virology 20100930 |
| Antitrypanosomal and antileishmanial activities of novel N-alkyl-(1-phenylsubstituted-beta-carboline)-3-carboxamides. | Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 20100701 |
| Discovery of a novel selective PPARgamma modulator from (-)-Cercosporamide derivatives. | Bioorganic & medicinal chemistry letters 20100401 |
| Heterologous expression of leader-less pga gene in Pichia pastoris: intracellular production of prokaryotic enzyme. | BMC biotechnology 20100101 |
| 2-(4-Bromo-phen-yl)-N-(2-methoxy-phen-yl)acetamide. | Acta crystallographica. Section E, Structure reports online 20100101 |
| Carbonic anhydrase inhibitors. Aromatic/heterocyclic sulfonamides incorporating phenacetyl, pyridylacetyl and thienylacetyl tails act as potent inhibitors of human mitochondrial isoforms VA and VB. | Bioorganic & medicinal chemistry 20090715 |
| Carbonic anhydrase inhibitors. Phenacetyl-, pyridylacetyl- and thienylacetyl-substituted aromatic sulfonamides act as potent and selective isoform VII inhibitors. | Bioorganic & medicinal chemistry letters 20090615 |
| N-(3,4-Diethoxy-phen-yl)acetamide. | Acta crystallographica. Section E, Structure reports online 20090601 |
| Utility of MetaSite in improving metabolic stability of the neutral indomethacin amide derivative and selective cyclooxygenase-2 inhibitor 2-(1-(4-chlorobenzoyl)-5-methoxy-2-methyl-1H-indol-3-yl)-N-phenethyl-acetamide. | Drug metabolism and disposition: the biological fate of chemicals 20090501 |
| Phenylethylamide and phenylmethylamide derivatives as new tyrosinase inhibitors. | Biological & pharmaceutical bulletin 20090201 |
| Regulation of phenylacetic acid degradation genes of Burkholderia cenocepacia K56-2. | BMC microbiology 20090101 |
| Novel inhibitors of the v-raf murine sarcoma viral oncogene homologue B1 (BRAF) based on a 2,6-disubstituted pyrazine scaffold. | Journal of medicinal chemistry 20080612 |
| Linear and cyclic peptides from the entomopathogenic bacterium Xenorhabdus nematophilus. | Journal of natural products 20080601 |
| QSAR and pharmacophore analysis on amides against drug-resistant S. aureus. | SAR and QSAR in environmental research 20080101 |
| The influence of leukotriene receptors' antagonists on experimentally induced ulcer in rats. | Revista medico-chirurgicala a Societatii de Medici si Naturalisti din Iasi 20080101 |
| 2,2-Dichloro-N-(2,3-dimethyl-phen-yl)acetamide. | Acta crystallographica. Section E, Structure reports online 20080101 |
| Production of enantiomerically pure (S)-beta-phenylalanine and (R)-beta-phenylalanine by penicillin G acylase from Escherichia coli in aqueous medium. | Biotechnology letters 20071201 |
| Diastereospecific photocyclization of a isopropylbenzophenone derivative in crystals and the morphological changes. | The Journal of organic chemistry 20070831 |
| Synthesis and biological evaluation of new N-(2-hydroxy-4(or 5)-nitro/aminophenyl)benzamides and phenylacetamides as antimicrobial agents. | Bioorganic & medicinal chemistry 20070301 |
| Fluorogenic substrates for lipases, esterases, and acylases using a TIM-mechanism for signal release. | Biotechnology journal 20070201 |
| Synthesis and receptor binding studies of 3-substituted piperazine derivatives. | European journal of medicinal chemistry 20060301 |
| [Studies on chemical constituents of the brown alga Dictyopteris divaricata]. | Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20060101 |
| Inhibition of cyclooxygenase with indomethacin phenethylamide reduces atherosclerosis in apoE-null mice. | Biochemical pharmacology 20050801 |
| SAR and pharmacokinetic studies on phenethylamide inhibitors of the hepatitis C virus NS3/NS4A serine protease. | Bioorganic & medicinal chemistry letters 20040906 |
| Thyroid receptor ligands. Part 2: Thyromimetics with improved selectivity for the thyroid hormone receptor beta. | Bioorganic & medicinal chemistry letters 20040705 |
| Mandelamide hydrolase from Pseudomonas putida: characterization of a new member of the amidase signature family. | Biochemistry 20040622 |
| Studies on anti-Helicobacter pylori agents. Part 3: A novel, efficacious cephem derivative, FR193879. | Bioorganic & medicinal chemistry letters 20040517 |
| Design, synthesis, and biological evaluation of new 8-heterocyclic xanthine derivatives as highly potent and selective human A2B adenosine receptor antagonists. | Journal of medicinal chemistry 20040311 |
| Studies on the metabolism of the novel, selective cyclooxygenase-2 inhibitor indomethacin phenethylamide in rat, mouse, and human liver microsomes: identification of active metabolites. | Drug metabolism and disposition: the biological fate of chemicals 20040101 |
| Metabolism of 2-phenylethylamine to phenylacetic acid, via the intermediate phenylacetaldehyde, by freshly prepared and cryopreserved guinea pig liver slices. | In vivo (Athens, Greece) 20040101 |
| Bhimamycin A to approximately E and bhimanone: isolation, structure elucidation and biological activity of novel quinone antibiotics from a terrestrial Streptomycete. | The Journal of antibiotics 20031101 |
| Novel, potent phenethylamide inhibitors of the hepatitis C virus (HCV) NS3 protease: probing the role of P2 aryloxyprolines with hybrid structures. | Bioorganic & medicinal chemistry letters 20030818 |
| Design of selective peptidomimetic agonists for the human orphan receptor BRS-3. | Journal of medicinal chemistry 20030508 |
| The scent of age. | Proceedings. Biological sciences 20030507 |
| Phenethyl amides as novel noncovalent inhibitors of hepatitis C virus NS3/4A protease: discovery, initial SAR, and molecular modeling. | Journal of medicinal chemistry 20030130 |
| Role of alphaArg145 and betaArg263 in the active site of penicillin acylase of Escherichia coli. | The Biochemical journal 20020701 |
| Synthesis and antimicrobial activity of some novel 2-(p-substituted-phenyl)-5-substituted-carbonylaminobenzoxazoles. | Farmaco (Societa chimica italiana : 1989) 20020301 |
| Synthesis and structure-activity relationships of N-(1-benzylpiperidin-4-yl)arylacetamide analogues as potent sigma1 receptor ligands. | Journal of medicinal chemistry 20011206 |
| A chemostat culture as a tool for the improvement of a recombinant E. coli strain over-producing penicillin G acylase. | Biotechnology and bioengineering 20011005 |
| An enzyme-labile safety catch linker for synthesis on a soluble polymeric support. | Chemistry (Weinheim an der Bergstrasse, Germany) 20010302 |
| Substitutions of Thr-103-Ile and Trp-138-Gly in amidase from Pseudomonas aeruginosa are responsible for altered kinetic properties and enzyme instability. | Molecular biotechnology 20010301 |
| Potent and use-dependent block of cardiac sodium channels by U-50,488H, a benzeneacetamide kappa opioid receptor agonist. | Experimental and clinical cardiology 20010101 |
| Isolation and characterization of a bacterium possessing a novel aldoxime-dehydration activity and nitrile-degrading enzymes. | Archives of microbiology 19980801 |
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