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Home > Other Building Blocks > 102225-38-7
102225-38-7 | Benzene, 1-[2-(4-butylphenyl)ethynyl]-4-propyl-
CAS No: 102225-38-7 Catalog No: AG0006YQ MDL No:
Product Description
Catalog Number:
AG0006YQ
Chemical Name:
Benzene, 1-[2-(4-butylphenyl)ethynyl]-4-propyl-
CAS Number:
102225-38-7
Molecular Formula:
C21H24
Molecular Weight:
276.4153
IUPAC Name:
1-butyl-4-[2-(4-propylphenyl)ethynyl]benzene
InChI:
InChI=1S/C21H24/c1-3-5-7-19-10-14-21(15-11-19)17-16-20-12-8-18(6-4-2)9-13-20/h8-15H,3-7H2,1-2H3
InChI Key:
CBWCLOQHNNGEAJ-UHFFFAOYSA-N
SMILES:
CCCCc1ccc(cc1)C#Cc1ccc(cc1)CCC
Properties
Complexity:
326
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
1
Defined Atom Stereocenter Count:
0
Defined Bond Stereocenter Count:
0
Exact Mass:
276.188g/mol
Formal Charge:
0
Heavy Atom Count:
21
Hydrogen Bond Acceptor Count:
0
Hydrogen Bond Donor Count:
0
Isotope Atom Count:
0
Molecular Weight:
276.423g/mol
Monoisotopic Mass:
276.188g/mol
Rotatable Bond Count:
7
Topological Polar Surface Area:
0A^2
Undefined Atom Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
XLogP3:
7.2
Literature
| Title | Journal |
|---|---|
| Galectin-3 contributes to vascular fibrosis in monocrotaline-induced pulmonary arterial hypertension rat model. | Journal of biochemical and molecular toxicology 20170501 |
| Systems level analysis and identification of pathways and networks associated with liver fibrosis. | PloS one 20140101 |
| De novo galectin-3 expression influences the response of melanoma cells to isatin-Schiff base copper (II) complex-induced oxidative stimulus. | Chemico-biological interactions 20131025 |
| Galectin-1 and galectin-3 in the corpus luteum of mice are differentially regulated by prolactin and prostaglandin F2α. | Reproduction (Cambridge, England) 20121101 |
| Galectin-3 protein regulates mobility of N-cadherin and GM1 ganglioside at cell-cell junctions of mammary carcinoma cells. | The Journal of biological chemistry 20120921 |
| Molecular recognition of the Thomsen-Friedenreich antigen-threonine conjugate by adhesion/growth regulatory galectin-3: nuclear magnetic resonance studies and molecular dynamics simulations. | Biochemistry 20120918 |
| Genetic variation in galectin-3 gene associates with cognitive function at old age. | Neurobiology of aging 20120901 |
| Galectin-3 expression in response to LPS, immunomodulatory drugs and exogenously added galectin-3 in monocyte-like THP-1 cells. | In vitro cellular & developmental biology. Animal 20120901 |
| Glycocodon theory--the first table of glycocodons. | Journal of theoretical biology 20120821 |
| Microarray expression analysis and identification of serum biomarkers for Niemann-Pick disease, type C1. | Human molecular genetics 20120815 |
| The antiapoptotic effect of galectin-3 in human endometrial cells under the regulation of estrogen and progesterone. | Biology of reproduction 20120801 |
| Expression of Ki-67, galectin-3, fragile histidine triad, and parafibromin in malignant and benign parathyroid tumors. | Chinese medical journal 20120801 |
| Characterization of the interaction between hydroxypropyl guar galactomannan and galectin-3. | Biochemical and biophysical research communications 20120720 |
| Differential glycosylation of MUC1 and CEACAM5 between normal mucosa and tumour tissue of colon cancer patients. | International journal of cancer 20120701 |
| The fibrosis marker galectin-3 and outcome in the general population. | Journal of internal medicine 20120701 |
| Galectin-3 endocytosis by carbohydrate independent and dependent pathways in different macrophage like cell types. | Biochimica et biophysica acta 20120701 |
| Distinct genetic alterations in pediatric glioblastomas. | Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery 20120701 |
| Dynamics and Distribution of Klothoβ (KLB) and fibroblast growth factor receptor-1 (FGFR1) in living cells reveal the fibroblast growth factor-21 (FGF21)-induced receptor complex. | The Journal of biological chemistry 20120608 |
| Elastin-derived peptides increase invasive capacities of lung cancer cells by post-transcriptional regulation of MMP-2 and uPA. | Clinical & experimental metastasis 20120601 |
| MUC1 carrying core 2 O-glycans functions as a molecular shield against NK cell attack, promoting bladder tumor metastasis. | International journal of oncology 20120601 |
| Role of galectin-3 in acetaminophen-induced hepatotoxicity and inflammatory mediator production. | Toxicological sciences : an official journal of the Society of Toxicology 20120601 |
| Aldosterone inhibits antifibrotic factors in mouse hypertensive heart. | Hypertension (Dallas, Tex. : 1979) 20120601 |
| Expression of different carbohydrate tumour markers and galectins 1 and 3 in normal squamous and malignant epithelia of the upper aaerodigestive tract. | Anticancer research 20120501 |
| Expression of the tumor markers sialyl Lewis A, sialyl Lewis X, Lewis Y, Thomsen-Friedenreich antigen, galectin-1 and galectin-3 in human osteoblasts in vitro. | Anticancer research 20120501 |
| Nuclear export of proteins and drug resistance in cancer. | Biochemical pharmacology 20120415 |
| Loss of effector function of human cytolytic T lymphocytes is accompanied by major alterations in N- and O-glycosylation. | The Journal of biological chemistry 20120330 |
| Taloside inhibitors of galectin-1 and galectin-3. | Chemical biology & drug design 20120301 |
| Reduction of galectin-3 expression and liver fibrosis after cell therapy in a mouse model of cirrhosis. | Cytotherapy 20120301 |
| Treatment of prostate carcinoma with (galectin-3)-targeted HPMA copolymer-(G3-C12)-5-Fluorouracil conjugates. | Biomaterials 20120301 |
| Tyrosine-phosphorylated galectin-3 protein is resistant to prostate-specific antigen (PSA) cleavage. | The Journal of biological chemistry 20120217 |
| Modified apple polysaccharide prevents against tumorigenesis in a mouse model of colitis-associated colon cancer: role of galectin-3 and apoptosis in cancer prevention. | European journal of nutrition 20120201 |
| Galectin-3 is a new MerTK-specific eat-me signal. | Journal of cellular physiology 20120201 |
| Galectin-3 modulates phagocytosis-induced stellate cell activation and liver fibrosis in vivo. | American journal of physiology. Gastrointestinal and liver physiology 20120201 |
| The carbohydrate-binding site in galectin-3 is preorganized to recognize a sugarlike framework of oxygens: ultra-high-resolution structures and water dynamics. | Biochemistry 20120110 |
| Galectin-3 inhibits the chemotaxis of human polymorphonuclear neutrophils in vitro. | Immunobiology 20120101 |
| Galectin-3 in ambulatory patients with heart failure: results from the HF-ACTION study. | Circulation. Heart failure 20120101 |
| Galectin-3 and the development of heart failure after acute coronary syndrome: pilot experience from PROVE IT-TIMI 22. | Clinical chemistry 20120101 |
| Neutrophil depletion reduces edema formation and tissue loss following traumatic brain injury in mice. | Journal of neuroinflammation 20120101 |
| How echinoccocosis affects potential cancer markers in plasma: galectin-3, sN-cadherin and sE-cadherin? A preliminary report. | Diagnostic pathology 20120101 |
| Inhibition of prostate cancer bone metastasis by synthetic TF antigen mimic/galectin-3 inhibitor lactulose-L-leucine. | Neoplasia (New York, N.Y.) 20120101 |
| Ibuprofen attenuates the inflammatory response and allows formation of migratory neuroblasts from grafted stem cells after traumatic brain injury. | Restorative neurology and neuroscience 20120101 |
| Hypoxia reduces arylsulfatase B activity and silencing arylsulfatase B replicates and mediates the effects of hypoxia. | PloS one 20120101 |
| Inhibition of phosphatidylcholine-specific phospholipase C results in loss of mesenchymal traits in metastatic breast cancer cells. | Breast cancer research : BCR 20120101 |
| Deficiency in galectin-3 promotes hepatic injury in CDAA diet-induced nonalcoholic fatty liver disease. | TheScientificWorldJournal 20120101 |
| A combinatorial extracellular matrix platform identifies cell-extracellular matrix interactions that correlate with metastasis. | Nature communications 20120101 |
| Soluble IgE receptors--elements of the IgE network. | Immunology letters 20111230 |
| Transient gene silencing of galectin-3 suppresses pancreatic cancer cell migration and invasion through degradation of β-catenin. | International journal of cancer 20111215 |
| Galectin-3 germline variant at position 191 enhances nuclear accumulation and activation of β-catenin in gastric cancer. | Clinical & experimental metastasis 20111201 |
| The bone marrow compartment is modified in the absence of galectin-3. | Cell and tissue research 20111201 |
| Investigation of galectin-3 and heparanase in endometrioid and serous carcinomas of the endometrium and correlation with known predictors of survival. | Archives of gynecology and obstetrics 20111101 |
| Hormonal regulation of galectin 3 in trophoblasts and its effects on endometrium. | Reproductive sciences (Thousand Oaks, Calif.) 20111101 |
| Transcriptional analysis of the endothelial response to diabetes reveals a role for galectin-3. | Physiological genomics 20111001 |
| Longitudinal changes in cardiac function after cisplatin-based chemotherapy for testicular cancer. | Annals of oncology : official journal of the European Society for Medical Oncology 20111001 |
| Systemic and hepatic vein galectin-3 are increased in patients with alcoholic liver cirrhosis and negatively correlate with liver function. | Cytokine 20110901 |
| Increased galectin-3 facilitates leukemia cell survival from apoptotic stimuli. | Biochemical and biophysical research communications 20110826 |
| Accurate predictions of nonpolar solvation free energies require explicit consideration of binding-site hydration. | Journal of the American Chemical Society 20110824 |
| A novel strategy for evasion of NK cell immunity by tumours expressing core2 O-glycans. | The EMBO journal 20110803 |
| Elevation of serum galectin-3 and liver stiffness measured by transient elastography in biliary atresia. | European journal of pediatric surgery : official journal of Austrian Association of Pediatric Surgery ... [et al] = Zeitschrift fur Kinderchirurgie 20110801 |
| Serum galectin-3 levels in patients with nonalcoholic fatty liver disease. | Clinical biochemistry 20110801 |
| Spinal inhibitory interneuron pathology follows motor neuron degeneration independent of glial mutant superoxide dismutase 1 expression in SOD1-ALS mice. | Journal of neuropathology and experimental neurology 20110801 |
| Galectin-3 secretion and tyrosine phosphorylation is dependent on the calpain small subunit, Calpain 4. | Biochemical and biophysical research communications 20110624 |
| Myenteric denervation downregulates galectin-1 and -3 expression in gastric carcinogenesis. | Digestive diseases and sciences 20110601 |
| Co-purification of Mac-2 binding protein with galectin-3 and association with prostasomes in human semen. | The Prostate 20110515 |
| Noninvasive assessment of atherosclerotic plaque progression in ApoE-/- mice using susceptibility gradient mapping. | Circulation. Cardiovascular imaging 20110501 |
| Macrophage migration inhibitory factor promotes cell death and aggravates neurologic deficits after experimental stroke. | Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 20110401 |
| Absence of galectin-3 does not affect the development of experimental tongue carcinomas in mice. | Experimental and molecular pathology 20110401 |
| Expression and detrimental role of hematopoietic prostaglandin D synthase in spinal cord contusion injury. | Glia 20110401 |
| Transient silencing of galectin-3 expression promotes both in vitro and in vivo drug-induced apoptosis of human pancreatic carcinoma cells. | Clinical & experimental metastasis 20110401 |
| Novel neuroinflammatory targets in the chronically injured spinal cord. | Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics 20110401 |
| Expression of myofibroblast activation molecules in proliferative vitreoretinopathy epiretinal membranes. | Acta ophthalmologica 20110301 |
| Negative regulation of RPE cell attachment by carbohydrate-dependent cell surface binding of galectin-3 and inhibition of the ERK-MAPK pathway. | Biochimie 20110301 |
| Galectin-3 is a substrate for prostate specific antigen (PSA) in human seminal plasma. | The Prostate 20110201 |
| Mesenchymal stem cell-mediated T cell suppression occurs through secreted galectins. | International journal of oncology 20110201 |
| Predictive value of plasma galectin-3 levels in heart failure with reduced and preserved ejection fraction. | Annals of medicine 20110201 |
| Galectin-3 binding protein promotes cell motility in colon cancer by stimulating the shedding of protein tyrosine phosphatase kappa by proprotein convertase 5. | Biochemical and biophysical research communications 20110107 |
| Clinicopathlogic and immunohistochemical characteristics of triple negative invasive lobular carcinoma. | Yonsei medical journal 20110101 |
| Arginine kinase from the cellar spider (Holocnemus pluchei): a new asthma-causing allergen. | International archives of allergy and immunology 20110101 |
| Modified citrus pectin reduces galectin-3 expression and disease severity in experimental acute kidney injury. | PloS one 20110101 |
| Gene expression profiling in lungs of chronic asthmatic mice treated with galectin-3: downregulation of inflammatory and regulatory genes. | Mediators of inflammation 20110101 |
| Lack of galectin-3 disturbs mesenteric lymph node homeostasis and B cell niches in the course of Schistosoma mansoni infection. | PloS one 20110101 |
| D-(+)-galactose-conjugated single-walled carbon nanotubes as new chemical probes for electrochemical biosensors for the cancer marker galectin-3. | International journal of molecular sciences 20110101 |
| The loss of the p53 activator HIPK2 is responsible for galectin-3 overexpression in well differentiated thyroid carcinomas. | PloS one 20110101 |
| Comprehensive analysis of cellular galectin-3 reveals no consistent oncogenic function in pancreatic cancer cells. | PloS one 20110101 |
| Bisphosphonate-associated osteonecrosis of the jaw is linked to suppressed TGFβ1-signaling and increased Galectin-3 expression: a histological study on biopsies. | Journal of translational medicine 20110101 |
| Galectin-3C inhibits tumor growth and increases the anticancer activity of bortezomib in a murine model of human multiple myeloma. | PloS one 20110101 |
| Wallerian degeneration: the innate-immune response to traumatic nerve injury. | Journal of neuroinflammation 20110101 |
| Structural basis for distinct binding properties of the human galectins to Thomsen-Friedenreich antigen. | PloS one 20110101 |
| Changes in the expression and subcellular distribution of galectin-3 in clear cell renal cell carcinoma. | Journal of experimental & clinical cancer research : CR 20110101 |
| Galectin-3 facilitates cell motility in gastric cancer by up-regulating protease-activated receptor-1 (PAR-1) and matrix metalloproteinase-1 (MMP-1). | PloS one 20110101 |
| Delayed inflammatory mRNA and protein expression after spinal cord injury. | Journal of neuroinflammation 20110101 |
| Galectin-3 and cyclin D1 expression in non-small cell lung cancer. | Journal of experimental & clinical cancer research : CR 20110101 |
| LPS-induced galectin-3 oligomerization results in enhancement of neutrophil activation. | PloS one 20110101 |
| MMP-13 stimulates osteoclast differentiation and activation in tumour breast bone metastases. | Breast cancer research : BCR 20110101 |
| Galectin-3 and Beclin1/Atg6 genes in human cancers: using cDNA tissue panel, qRT-PCR, and logistic regression model to identify cancer cell biomarkers. | PloS one 20110101 |
| Galectin-3 mediates cross-talk between K-Ras and Let-7c tumor suppressor microRNA. | PloS one 20110101 |
| Galectin-1 is part of human trophoblast invasion machinery--a functional study in vitro. | PloS one 20110101 |
| Diagnostic significance of CK19, TG, Ki67 and galectin-3 expression for papillary thyroid carcinoma in the northeastern region of China. | Diagnostic pathology 20110101 |
| Hyperglycemia in apolipoprotein E-deficient mouse strains with different atherosclerosis susceptibility. | Cardiovascular diabetology 20110101 |
| The promigratory activity of the matricellular protein galectin-3 depends on the activation of PI-3 kinase. | PloS one 20110101 |
| Galectin inhibitory disaccharides promote tumour immunity in a breast cancer model. | Cancer letters 20101228 |
| Diagnostic and prognostic role of galectin 3 expression in cutaneous melanoma. | The American Journal of dermatopathology 20101201 |
| Galectin-3 exerts cytokine-like regulatory actions through the JAK-STAT pathway. | Journal of immunology (Baltimore, Md. : 1950) 20101201 |
| Multiple cellular proteins modulate the dynamics of K-ras association with the plasma membrane. | Biophysical journal 20101117 |
| Mutational tuning of galectin-3 specificity and biological function. | The Journal of biological chemistry 20101105 |
| Characterization of lupin major allergens (Lupinus albus L.). | Molecular nutrition & food research 20101101 |
| A novel function of microRNA let-7d in regulation of galectin-3 expression in attention deficit hyperactivity disorder rat brain. | Brain pathology (Zurich, Switzerland) 20101101 |
| Calpain activation through galectin-3 inhibition sensitizes prostate cancer cells to cisplatin treatment. | Cell death & disease 20101101 |
| Protein flexibility and conformational entropy in ligand design targeting the carbohydrate recognition domain of galectin-3. | Journal of the American Chemical Society 20101020 |
| Galectin-3: A novel substrate for c-Abl kinase. | Biochimica et biophysica acta 20101001 |
| Age-related motor neuron degeneration in DNA repair-deficient Ercc1 mice. | Acta neuropathologica 20101001 |
| c-Abl and Arg tyrosine kinases regulate lysosomal degradation of the oncoprotein Galectin-3. | Cell death and differentiation 20100801 |
| Differential cellular localization of galectin-1 and galectin-3 in the regressing corpus luteum of mice and their possible contribution to luteal cell elimination. | The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society 20100801 |
| Galectin-3, cardiac structure and function, and long-term mortality in patients with acutely decompensated heart failure. | European journal of heart failure 20100801 |
| How adhesion/growth-regulatory galectins-1 and -3 attain cell specificity: case study defining their target on neuroblastoma cells (SK-N-MC) and marked affinity regulation by affecting microdomain organization of the membrane. | IUBMB life 20100801 |
| Galectin-3 promotes chronic activation of K-Ras and differentiation block in malignant thyroid carcinomas. | Molecular cancer therapeutics 20100801 |
| Mathematical modeling of K-Ras nanocluster formation on the plasma membrane. | Biophysical journal 20100721 |
| 1H-1,2,3-triazol-1-yl thiodigalactoside derivatives as high affinity galectin-3 inhibitors. | Bioorganic & medicinal chemistry 20100715 |
| Antiproliferative and proapoptotic actions of okra pectin on B16F10 melanoma cells. | Phytotherapy research : PTR 20100701 |
| Clinical, hormonal and molecular characterization of pituitary ACTH adenomas without (silent corticotroph adenomas) and with Cushing's disease. | European journal of endocrinology 20100701 |
| Galectin-3 plays a modulatory role in the life span and activation of murine neutrophils during early Toxoplasma gondii infection. | Immunobiology 20100601 |
| A novel clinically relevant animal model for studying galectin-3 and its ligands during colon carcinogenesis. | The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society 20100601 |
| GCS-100, a novel galectin-3 antagonist, modulates MCL-1, NOXA, and cell cycle to induce myeloma cell death. | Blood 20100513 |
| KSHV downregulation of galectin-3 in Kaposi's sarcoma. | Glycobiology 20100501 |
| Prognostic value of galectin-3, a novel marker of fibrosis, in patients with chronic heart failure: data from the DEAL-HF study. | Clinical research in cardiology : official journal of the German Cardiac Society 20100501 |
| Multi-center determination of galectin-3 assay performance characteristics: Anatomy of a novel assay for use in heart failure. | Clinical biochemistry 20100501 |
| Human galectin-3 interacts with two anticancer drugs. | Proteomics 20100501 |
| Immobilization of anti-galectin-3 onto polysiloxane-polyvinyl alcohol disks for tumor prostatic diseases diagnosis. | Applied biochemistry and biotechnology 20100401 |
| Galectin-3 contributes to neonatal hypoxic-ischemic brain injury. | Neurobiology of disease 20100401 |
| Galectin-3 increases gastric cancer cell motility by up-regulating fascin-1 expression. | Gastroenterology 20100301 |
| Serum galectin-3 is elevated in obesity and negatively correlates with glycosylated hemoglobin in type 2 diabetes. | The Journal of clinical endocrinology and metabolism 20100301 |
| Galectin-3 in cardiac remodeling and heart failure. | Current heart failure reports 20100301 |
| Dynamics of galectin-3 in the nucleus and cytoplasm. | Biochimica et biophysica acta 20100201 |
| Alterations of matrix metalloproteinases, gastric mucin and prostaglandin E(2) levels by pectic polysaccharide of swallow root (Decalepis hamiltonii) during ulcer healing. | Biochimie 20100201 |
| Clinical trials update from the Heart Failure Society of America Meeting 2009: FAST, IMPROVE-HF, COACH galectin-3 substudy, HF-ACTION nuclear substudy, DAD-HF, and MARVEL-1. | European journal of heart failure 20100201 |
| Implication of the Galectin-3 in colorectal cancer development (about 325 Tunisian patients). | Bulletin du cancer 20100201 |
| CD133(+) human pulmonary adenocarcinoma cells induce apoptosis of CD8(+) T cells by highly expressed galectin-3. | Clinical and investigative medicine. Medecine clinique et experimentale 20100201 |
| Bisecting GlcNAc residues on laminin-332 down-regulate galectin-3-dependent keratinocyte motility. | The Journal of biological chemistry 20100129 |
| In pursuit of prognostic factors in children with pilocytic astrocytomas. | Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery 20100101 |
| Utility of immunohistochemical markers in differentiating benign from malignant follicular-derived thyroid nodules. | Diagnostic pathology 20100101 |
| In vivo tumor cell adhesion in the pulmonary microvasculature is exclusively mediated by tumor cell--endothelial cell interaction. | BMC cancer 20100101 |
| Platelet-activating factor receptor (PAF-R)-dependent pathways control tumour growth and tumour response to chemotherapy. | BMC cancer 20100101 |
| Chronic upregulation of activated microglia immunoreactive for galectin-3/Mac-2 and nerve growth factor following diffuse axonal injury. | Journal of neuroinflammation 20100101 |
| Interaction between circulating galectin-3 and cancer-associated MUC1 enhances tumour cell homotypic aggregation and prevents anoikis. | Molecular cancer 20100101 |
| Lack of galectin-3 alleviates trypanosomiasis-associated anemia of inflammation. | Immunobiology 20100101 |
| Involvement of Galectin-3 with vascular cell adhesion molecule-1 in growth regulation of mouse BALB/3T3 cells. | The Journal of biological chemistry 20091218 |
| Adiponectin downregulates galectin-3 whose cellular form is elevated whereas its soluble form is reduced in type 2 diabetic monocytes. | FEBS letters 20091119 |
| Interactions between galectin-3 and integrinbeta3 in regulating endometrial cell proliferation and adhesion. | Human reproduction (Oxford, England) 20091101 |
| Suppression of galectin-3 expression enhances apoptosis and chemosensitivity in liver fluke-associated cholangiocarcinoma. | Cancer science 20091101 |
| Fragment-based development of triazole-substituted O-galactosyl aldoximes with fragment-induced affinity and selectivity for galectin-3. | Organic & biomolecular chemistry 20091007 |
| Evaluation of the prognostic significance of serum galectin-3 in American Joint Committee on Cancer stage III and stage IV melanoma patients. | Melanoma research 20091001 |
| Regulation of expression and secretion of galectin-3 in human monocyte-derived dendritic cells. | Molecular immunology 20091001 |
| Conformational entropy changes upon lactose binding to the carbohydrate recognition domain of galectin-3. | Journal of biomolecular NMR 20090901 |
| Immunohistochemical localization of galectin-3 in the granulomatous lesions of paratuberculosis-infected bovine intestine. | Journal of veterinary science 20090901 |
| Synthetic galectin-3 inhibitor increases metastatic cancer cell sensitivity to taxol-induced apoptosis in vitro and in vivo. | Neoplasia (New York, N.Y.) 20090901 |
| Galectin-3 negatively regulates TCR-mediated CD4+ T-cell activation at the immunological synapse. | Proceedings of the National Academy of Sciences of the United States of America 20090825 |
| Association of cell surface mucins with galectin-3 contributes to the ocular surface epithelial barrier. | The Journal of biological chemistry 20090821 |
| A mechanism for incorporation of galectin-3 into the spliceosome through its association with U1 snRNP. | Biochemistry 20090818 |
| Detection of galectin-3 in patients with inflammatory bowel diseases: new serum marker of active forms of IBD? | Inflammation research : official journal of the European Histamine Research Society ... [et al.] 20090801 |
| Mass spectrometry (LC-MS/MS) site-mapping of N-glycosylated membrane proteins for breast cancer biomarkers. | Journal of proteome research 20090801 |
| Synthesis and evaluation of new thiodigalactoside-based chemical probes to label galectin-3. | Chembiochem : a European journal of chemical biology 20090706 |
| Advanced lipoxidation end-products mediate lipid-induced glomerular injury: role of receptor-mediated mechanisms. | The Journal of pathology 20090701 |
| Activation of metabotropic glutamate receptor 5 improves recovery after spinal cord injury in rodents. | Annals of neurology 20090701 |
| Effects of advanced glycosylation end products and rosiglitazone on the expression and secretion of galectin-3 in human renal mesangial cells. | Chinese medical journal 20090505 |
| Poly N-acetyllactosamine substitutions on N- and not O-oligosaccharides or Thomsen-Friedenreich antigen facilitate lung specific metastasis of melanoma cells via galectin-3. | Glycoconjugate journal 20090501 |
| NMR resonance assignments of sparsely labeled proteins: amide proton exchange correlations in native and denatured states. | Journal of the American Chemical Society 20090415 |
| Recognition of galactan components of pectin by galectin-3. | FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20090201 |
| Phosphorylated human lectin galectin-3: analysis of ligand binding by histochemical monitoring of normal/malignant squamous epithelia and by isothermal titration calorimetry. | Anatomia, histologia, embryologia 20090201 |
| N-acetyl-seryl-aspartyl-lysyl-proline prevents cardiac remodeling and dysfunction induced by galectin-3, a mammalian adhesion/growth-regulatory lectin. | American journal of physiology. Heart and circulatory physiology 20090201 |
| Novel fluorescent glycan microarray strategy reveals ligands for galectins. | Chemistry & biology 20090130 |
| Galectin-3-mediated xenoactivation of human monocytes. | Transplantation 20090115 |
| Targeted disruption of the galectin-3 gene results in decreased susceptibility to multiple low dose streptozotocin-induced diabetes in mice. | Clinical immunology (Orlando, Fla.) 20090101 |
| Galectin-3 functions as an opsonin and enhances the macrophage clearance of apoptotic neutrophils. | Glycobiology 20090101 |
| Genetic assessment of the importance of galectin-3 in cancer initiation, progression, and dissemination in mice. | Glycobiology 20090101 |
| Galectin-3 stabilizes heterogeneous nuclear ribonucleoprotein Q to maintain proliferation of human colon cancer cells. | Cellular and molecular life sciences : CMLS 20090101 |
| Lack of galectin-3 drives response to Paracoccidioides brasiliensis toward a Th2-biased immunity. | PloS one 20090101 |
| Herpes simplex virus type 1 infection increases the carbohydrate binding activity and the secretion of cellular galectin-3. | Archives of virology 20090101 |
| Duodenal intraepithelial lymphocytes of children with cow milk allergy preferentially bind the glycan-binding protein galectin-3. | International journal of immunopathology and pharmacology 20090101 |
| Pathogenic roles of CD14, galectin-3, and OX40 during experimental cerebral malaria in mice. | PloS one 20090101 |
| Immunohistochemical localization of galectin-3 in the pig retina during postnatal development. | Molecular vision 20090101 |
| Upregulation of oxidative stress markers in human microvascular endothelial cells by complexes of serum albumin and digestion products of glycated casein. | Journal of biochemical and molecular toxicology 20090101 |
| Racial disparity in breast cancer and functional germ line mutation in galectin-3 (rs4644): a pilot study. | Cancer research 20081215 |
| Purification and biochemical characterization of a novel allergenic protein from tatary buckwheat seeds. | Planta medica 20081201 |
| Immunohistochemical study of galectin-3 in mature and immature bull testis and epididymis. | Journal of veterinary science 20081201 |
| Characterization of major allergens of royal jelly Apis mellifera. | Tropical biomedicine 20081201 |
| The macrophage-derived neutrophil chemotactic factor, MNCF: a lectin with TNF-alpha-like activities on neutrophils. | Biochemical and biophysical research communications 20081128 |
| The beta-galactoside binding immunomodulatory lectin galectin-3 reverses the desensitized state induced in neutrophils by the chemotactic peptide f-Met-Leu-Phe: role of reactive oxygen species generated by the NADPH-oxidase and inactivation of the agonist. | Glycobiology 20081101 |
| Galectin-3 protects keratinocytes from UVB-induced apoptosis by enhancing AKT activation and suppressing ERK activation. | The Journal of investigative dermatology 20081001 |
| A Role for galectin-3 in renal tissue damage triggered by ischemia and reperfusion injury. | Transplant international : official journal of the European Society for Organ Transplantation 20081001 |
| Dissociation of the carbohydrate-binding and splicing activities of galectin-1. | Archives of biochemistry and biophysics 20081001 |
| Low expression of Bax predicts poor prognosis in resected non-small cell lung cancer patients with non-squamous histology. | Japanese journal of clinical oncology 20081001 |
| Identification of mitochondrial F(1)F(0)-ATP synthase interacting with galectin-3 in colon cancer cells. | Cancer science 20081001 |
| Analogs of tetrahydroisoquinoline natural products that inhibit cell migration and target galectin-3 outside of its carbohydrate-binding site. | The Journal of biological chemistry 20080905 |
| Novel transcript profiling of diffuse alveolar damage induced by hyperoxia exposure in mice: normalization by glyceraldehyde 3-phosphate dehydrogenase. | International journal of legal medicine 20080901 |
| Cell-type-specific expression of murine multifunctional galectin-3 and its association with follicular atresia/luteolysis in contrast to pro-apoptotic galectins-1 and -7. | Histochemistry and cell biology 20080901 |
| Tumor-associated galectin-3 modulates the function of tumor-reactive T cells. | Cancer research 20080901 |
| Synthesis of stable and selective inhibitors of human galectins-1 and -3. | Bioorganic & medicinal chemistry 20080815 |
| Galectin-3 is a negative regulator of lipopolysaccharide-mediated inflammation. | Journal of immunology (Baltimore, Md. : 1950) 20080815 |
| K-ras nanoclustering is subverted by overexpression of the scaffold protein galectin-3. | Cancer research 20080815 |
| Distinct effects on splicing of two monoclonal antibodies directed against the amino-terminal domain of galectin-3. | Archives of biochemistry and biophysics 20080715 |
| Assessing the inhibitory potency of galectin ligands identified from combinatorial (glyco)peptide libraries using surface plasmon resonance spectroscopy. | Analytical biochemistry 20080715 |
| Identification of galectin-3-binding protein as a factor secreted by tumor cells that stimulates interleukin-6 expression in the bone marrow stroma. | The Journal of biological chemistry 20080704 |
| Targeted disruption of the galectin-3 gene results in decreased susceptibility to NNK-induced lung tumorigenesis: an oligonucleotide microarray study. | Journal of cancer research and clinical oncology 20080701 |
| Protein subtype-targeting through ligand epimerization: talose-selectivity of galectin-4 and galectin-8. | Bioorganic & medicinal chemistry letters 20080701 |
| Genetic networks of cooperative redox regulation of osteopontin. | Matrix biology : journal of the International Society for Matrix Biology 20080601 |
| Galectin-3 regulates RasGRP4-mediated activation of N-Ras and H-Ras. | Biochimica et biophysica acta 20080601 |
| Structural basis for chitotetraose coordination by CGL3, a novel galectin-related protein from Coprinopsis cinerea. | Journal of molecular biology 20080523 |
| Locally generated VGVAPG and VAPG elastin-derived peptides amplify melanoma invasion via the galectin-3 receptor. | International journal of cancer 20080501 |
| Galectin-3 but not galectin-1 induces mast cell death by oxidative stress and mitochondrial permeability transition. | Biochimica et biophysica acta 20080501 |
| Regulation of galectin-3 function in mucosal fibroblasts: potential role in mucosal inflammation. | Clinical and experimental immunology 20080501 |
| 111In-labeled galectin-3-targeting peptide as a SPECT agent for imaging breast tumors. | Journal of nuclear medicine : official publication, Society of Nuclear Medicine 20080501 |
| Galectin-1, -2, and -3 exhibit differential recognition of sialylated glycans and blood group antigens. | The Journal of biological chemistry 20080411 |
| Arginine binding motifs: design and synthesis of galactose-derived arginine tweezers as galectin-3 inhibitors. | Journal of medicinal chemistry 20080410 |
| Pancreatic stellate cells promote proliferation and invasiveness of human pancreatic cancer cells via galectin-3. | World journal of gastroenterology 20080407 |
| Increased expression of the gamma-secretase components presenilin-1 and nicastrin in activated astrocytes and microglia following traumatic brain injury. | Glia 20080401 |
| Phosphorylated human galectin-3: facile large-scale preparation of active lectin and detection of structural changes by CD spectroscopy. | Biochimica et biophysica acta 20080401 |
| [Cancer-associated carbohydrate-binding protein galectin-3 and its therapeutic ligands]. | Sheng li ke xue jin zhan [Progress in physiology] 20080401 |
| Novel anti-inflammatory mechanisms of N-Acetyl-Ser-Asp-Lys-Pro in hypertension-induced target organ damage. | American journal of physiology. Heart and circulatory physiology 20080301 |
| Cell surface N-glycosylation and sialylation regulate galectin-3-induced apoptosis in human diffuse large B cell lymphoma. | Oncology reports 20080301 |
| Differential roles of galectin-1 and galectin-3 in regulating leukocyte viability and cytokine secretion. | Journal of immunology (Baltimore, Md. : 1950) 20080301 |
| Combined immunostaining with galectin-3, fibronectin-1, CITED-1, Hector Battifora mesothelial-1, cytokeratin-19, peroxisome proliferator-activated receptor-{gamma}, and sodium/iodide symporter antibodies for the differential diagnosis of non-medullary thyroid carcinoma. | European journal of endocrinology 20080301 |
| Regulation of alternative macrophage activation by galectin-3. | Journal of immunology (Baltimore, Md. : 1950) 20080215 |
| Intracellular localisation of galectin-3 has a protective role in chondrocyte survival. | Annals of the rheumatic diseases 20080201 |
| Galectin-3 expression in human papillary thyroid carcinoma. | Cancer genomics & proteomics 20080101 |
| Rosiglitazone attenuates allergic inflammation and inhibits expression of galectin-3 in a mouse model of allergic rhinitis. | The Journal of international medical research 20080101 |
| High-throughput gene expression profiling of memory differentiation in primary human T cells. | BMC immunology 20080101 |
| Thyroid cancer imaging in vivo by targeting the anti-apoptotic molecule galectin-3. | PloS one 20080101 |
| Galectin-3 functions as an adhesion molecule to support eosinophil rolling and adhesion under conditions of flow. | Journal of immunology (Baltimore, Md. : 1950) 20071201 |
| Invasive Candida species disease in infants and children: occurrence, risk factors, management, and innate host defense mechanisms. | Current opinion in pediatrics 20071201 |
| Combined analysis of galectin-3 and BRAFV600E improves the accuracy of fine-needle aspiration biopsy with cytological findings suspicious for papillary thyroid carcinoma. | Endocrine-related cancer 20071201 |
| Inhibition of galectin-3 mediated cellular interactions by pectic polysaccharides from dietary sources. | Glycoconjugate journal 20071101 |
| Biological applications of a chimeric probe for the assessment of galectin-3 ligands. | The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society 20071001 |
| The MUC1 and galectin-3 oncoproteins function in a microRNA-dependent regulatory loop. | Molecular cell 20070921 |
| Synthesis of galactose-mimicking 1H-(1,2,3-triazol-1-yl)-mannosides as selective galectin-3 and 9N inhibitors. | Carbohydrate research 20070903 |
| Studies of arginine-arene interactions through synthesis and evaluation of a series of galectin-binding aromatic lactose esters. | Chembiochem : a European journal of chemical biology 20070813 |
| Diagnostic value of galectin-3, HBME-1, cytokeratin 19, high molecular weight cytokeratin, cyclin D1 and p27(kip1) in the differential diagnosis of thyroid nodules. | Journal of Korean medical science 20070801 |
| NMR resonance assignments for sparsely 15N labeled proteins. | Journal of biomolecular NMR 20070701 |
| Differential expression of galectins in normal, benign and malignant prostate epithelial cells: silencing of galectin-3 expression in prostate cancer by its promoter methylation. | Biochemical and biophysical research communications 20070622 |
| Membrane trafficking of CD98 and its ligand galectin 3 in BeWo cells--implication for placental cell fusion. | The FEBS journal 20070601 |
| The role of galectin-3 in cancer drug resistance. | Drug resistance updates : reviews and commentaries in antimicrobial and anticancer chemotherapy 20070601 |
| SPARC upregulates MT1-MMP expression, MMP-2 activation, and the secretion and cleavage of galectin-3 in U87MG glioma cells. | Neuroscience letters 20070529 |
| Galectin-3 inhibits Schwann cell proliferation in cultured sciatic nerve. | Neuroreport 20070507 |
| Galectins in the mouse ovary: concomitant expression of galectin-3 and progesterone degradation enzyme (20alpha-HSD) in the corpus luteum. | The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society 20070501 |
| Enhanced cell-to-cell contacts between activated microglia and pyramidal cell dendrites following kainic acid-induced neurotoxicity in the hippocampus. | Journal of neuroimmunology 20070501 |
| Bound-state residual dipolar couplings for rapidly exchanging ligands of His-tagged proteins. | Journal of the American Chemical Society 20070418 |
| Hepatic expression of galectin-3 and receptor for advanced glycation end products in patients with liver disease. | Journal of clinical pathology 20070401 |
| Gene expression profiles of endothelial progenitor cells by oligonucleotide microarray analysis. | Molecular and cellular biochemistry 20070401 |
| Selective ablation of proliferating microglial cells exacerbates ischemic injury in the brain. | The Journal of neuroscience : the official journal of the Society for Neuroscience 20070307 |
| Slow diffusion of lactose out of galectin-3 crystals monitored by X-ray crystallography: possible implications for ligand-exchange protocols. | Acta crystallographica. Section D, Biological crystallography 20070301 |
| A role for galectin-3 in CD13-mediated homotypic aggregation of monocytes. | Biochemical and biophysical research communications 20070216 |
| Expression of galectin-3 and its regulation in the testes. | International journal of andrology 20070201 |
| Detection of galectin-3 by novel peptidic photoprobes. | Bioorganic & medicinal chemistry letters 20070115 |
| Soluble galectin-3 is a strong, colonic epithelial-cell-derived, lamina propria fibroblast-stimulating factor. | Gut 20070101 |
| Extracellular localization of galectin-3 has a deleterious role in joint tissues. | Arthritis research & therapy 20070101 |
| Inhibition of advanced glycation and absence of galectin-3 prevent blood-retinal barrier dysfunction during short-term diabetes. | Experimental diabetes research 20070101 |
| Galectin-3 as a marker distinguishing functioning from silent corticotroph adenomas. | Hormones (Athens, Greece) 20070101 |
| Importin-mediated nuclear translocation of galectin-3. | The Journal of biological chemistry 20061222 |
| A new chemical probe for the detection of the cancer-linked galectin-3. | Organic & biomolecular chemistry 20061207 |
| Disrupted galectin-3 causes non-alcoholic fatty liver disease in male mice. | The Journal of pathology 20061201 |
| Role of galectin-3 in mast cell functions: galectin-3-deficient mast cells exhibit impaired mediator release and defective JNK expression. | Journal of immunology (Baltimore, Md. : 1950) 20061015 |
| UVA-activated 8-methoxypsoralen (PUVA) causes G2/M cell cycle arrest in Karpas 299 T-lymphoma cells. | Journal of photochemistry and photobiology. B, Biology 20061002 |
| Homology between ABH-carrier alpha2-seminoglycoprotein and Mac-2 binding protein. | Legal medicine (Tokyo, Japan) 20061001 |
| Galectin-3 induces death of Candida species expressing specific beta-1,2-linked mannans. | Journal of immunology (Baltimore, Md. : 1950) 20061001 |
| Solid and pseudopapillary tumor of the pancreas--review and new insights into pathogenesis. | The American journal of surgical pathology 20061001 |
| Screening for galectin-3 inhibitors from synthetic lacto-N-biose libraries using microscale affinity chromatography coupled to mass spectrometry. | The Journal of organic chemistry 20060915 |
| A first QSAR model for galectin-3 glycomimetic inhibitors based on 3D docked structures. | Medicinal chemistry (Shariqah (United Arab Emirates)) 20060901 |
| Tumor-associated antigen 90K/Mac-2-binding protein: possible role in colon cancer. | Journal of cellular biochemistry 20060801 |
| [The roles of interleukin-5 and eotaxin in signal transmission between lung and bone marrow of rat asthmatic models]. | Zhonghua jie he he hu xi za zhi = Zhonghua jiehe he huxi zazhi = Chinese journal of tuberculosis and respiratory diseases 20060801 |
| Large needle aspiration biopsy and galectin-3 determination in selected thyroid nodules with indeterminate FNA-cytology. | British journal of cancer 20060717 |
| Human monocytes recognize porcine endothelium via the interaction of galectin 3 and alpha-GAL. | Journal of immunology (Baltimore, Md. : 1950) 20060715 |
| Immunohistochemical and in situ hybridization analysis of galectin-3, a beta-galactoside binding lectin, in the urinary system of adult mice. | Histochemistry and cell biology 20060701 |
| Towards functional glycomics by localization of binding sites for tissue lectins: lectin histochemical reactivity for galectins during diethylstilbestrol-induced kidney tumorigenesis in male Syrian hamster. | Histochemistry and cell biology 20060701 |
| Transport of galectin-3 between the nucleus and cytoplasm. II. Identification of the signal for nuclear export. | Glycobiology 20060701 |
| UBD, a downstream element of FOXP3, allows the identification of LGALS3, a new marker of human regulatory T cells. | Laboratory investigation; a journal of technical methods and pathology 20060701 |
| A new hypothesis on the role of c-erbB2 oncogene in the progress of breast cancer. | Bulletin of experimental biology and medicine 20060701 |
| Galectin-3 in macrophage-like cells exposed to immunomodulatory drugs. | Biochimica et biophysica acta 20060401 |
| Galectin-3: an open-ended story. | Biochimica et biophysica acta 20060401 |
| Galectin-3 regulates myofibroblast activation and hepatic fibrosis. | Proceedings of the National Academy of Sciences of the United States of America 20060328 |
| Aryl O- and S-galactosides and lactosides as specific inhibitors of human galectins-1 and -3: role of electrostatic potential at O-3. | Bioorganic & medicinal chemistry letters 20060315 |
| Galectin-3 regulates mitochondrial stability and antiapoptotic function in response to anticancer drug in prostate cancer. | Cancer research 20060315 |
| LacdiNAc- and LacNAc-containing glycans induce granulomas in an in vivo model for schistosome egg-induced hepatic granuloma formation. | Glycobiology 20060301 |
| Expression of two temporally distinct microglia-related gene clusters after spinal cord injury. | Glia 20060301 |
| Inflammation-induced modulation of cellular galectin-1 and -3 expression in a model of rat peritonitis. | Inflammation research : official journal of the European Histamine Research Society ... [et al.] 20060301 |
| The galectin-3 gene promoter binding proteins in the liver of rats 48-h post-treatment with CCl4. | Gene 20060215 |
| Expressions of galectin-3, glutathione S-transferase A2 and peroxiredoxin-1 by nonylphenol-incubated Caco-2 cells and reduction in transepithelial electrical resistance by nonylphenol. | Toxicology in vitro : an international journal published in association with BIBRA 20060201 |
| Inhibition of chronic airway inflammation and remodeling by galectin-3 gene therapy in a murine model. | Journal of immunology (Baltimore, Md. : 1950) 20060201 |
| Potential involvement of galectin-3 and SNAP23 in Aeromonas hydrophila cytotoxic enterotoxin-induced host cell apoptosis. | Microbial pathogenesis 20060201 |
| Proteomic profiling of regionalized proteins in rat epididymis indicates consistency between specialized distribution and protein functions. | Journal of proteome research 20060201 |
| Exploring the role of galectin 3 in kidney function: a genetic approach. | Glycobiology 20060101 |
| High serum galectin-3 in advanced melanoma: preliminary results. | Clinical and experimental dermatology 20060101 |
| Pholcodine stimulates a dramatic increase of IgE in IgE-sensitized individuals. A pilot study. | Allergy 20060101 |
| Identification of blood biomarkers of rheumatoid arthritis by transcript profiling of peripheral blood mononuclear cells from the rat collagen-induced arthritis model. | Arthritis research & therapy 20060101 |
| Spatiotemporal organization of Ras signaling: rasosomes and the galectin switch. | Cellular and molecular neurobiology 20060101 |
| Effective solvation of alkaline earth ions by proline-rich proteolytic peptides of galectin-3 upon electrospray ionisation. | Rapid communications in mass spectrometry : RCM 20060101 |
| The binding of mycolic acids to galectin-3: a novel interaction between a host soluble lectin and trafficking mycobacterial lipids? | FEBS letters 20051219 |
| Galectin-3 interacts with membrane lipids and penetrates the lipid bilayer. | Biochemical and biophysical research communications 20051216 |
| Galectin-3 immunodetection in follicular thyroid neoplasms: a prospective study on fine-needle aspiration samples. | British journal of cancer 20051114 |
| A novel carbohydrate-based therapeutic GCS-100 overcomes bortezomib resistance and enhances dexamethasone-induced apoptosis in multiple myeloma cells. | Cancer research 20050915 |
| Development of age-dependent glomerular lesions in galectin-3/AGE-receptor-3 knockout mice. | American journal of physiology. Renal physiology 20050901 |
| Galectin-3 inhibits tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis by activating Akt in human bladder carcinoma cells. | Cancer research 20050901 |
| Galectin-3 and proliferating cell nuclear antigen (PCNA) expression in papillary thyroid carcinoma. | Experimental oncology 20050901 |
| Galectin-3 regulates a molecular switch from N-Ras to K-Ras usage in human breast carcinoma cells. | Cancer research 20050815 |
| C2-symmetrical thiodigalactoside bis-benzamido derivatives as high-affinity inhibitors of galectin-3: efficient lectin inhibition through double arginine-arene interactions. | Angewandte Chemie (International ed. in English) 20050812 |
| Correlation of expression of nuclear proteins pKi67 and p63 with lectin histochemical features in head and neck squamous cell cancer. | International journal of oncology 20050801 |
| Galectin-3 expression in papillary microcarcinoma of the thyroid. | Histopathology 20050801 |
| Galectin-3 expression in follicular tumours: an immunohistochemical study of its use as a marker of follicular carcinoma. | Pathology 20050801 |
| 3-(1,2,3-Triazol-1-yl)-1-thio-galactosides as small, efficient, and hydrolytically stable inhibitors of galectin-3. | Bioorganic & medicinal chemistry letters 20050715 |
| Global DNA methylation evaluation: potential complementary marker in differential diagnosis of thyroid neoplasia. | Virchows Archiv : an international journal of pathology 20050701 |
| Up-regulation of gene expression by hypoxia is mediated predominantly by hypoxia-inducible factor 1 (HIF-1). | The Journal of pathology 20050701 |
| Synthesis of O-galactosyl aldoximes as potent LacNAc-mimetic galectin-3 inhibitors. | Bioorganic & medicinal chemistry letters 20050502 |
| Galectin-3 and soluble fibrinogen act in concert to modulate neutrophil activation and survival: involvement of alternative MAPK pathways. | Glycobiology 20050501 |
| [Inhibitory effects of Galectin-3 on the inflammatory cytokines and chemokines in guinea pig asthma models]. | Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition 20050501 |
| Mechanical entrapment is insufficient and intercellular adhesion is essential for metastatic cell arrest in distant organs. | Neoplasia (New York, N.Y.) 20050501 |
| Determination of structural and functional overlap/divergence of five proto-type galectins by analysis of the growth-regulatory interaction with ganglioside GM1 in silico and in vitro on human neuroblastoma cells. | International journal of cancer 20050310 |
| Impaired retinal angiogenesis in diabetes: role of advanced glycation end products and galectin-3. | Diabetes 20050301 |
| Structural and thermodynamic studies on cation-Pi interactions in lectin-ligand complexes: high-affinity galectin-3 inhibitors through fine-tuning of an arginine-arene interaction. | Journal of the American Chemical Society 20050216 |
| Effects of DNA methylation on galectin-3 expression in pituitary tumors. | Cancer research 20050215 |
| Human galectin-3 immunoexpression in thyroid follicular adenomas with cell atypia. | Journal of endocrinological investigation 20050201 |
| Toward functional glycomics by localization of tissue lectins: immunohistochemical galectin fingerprinting during diethylstilbestrol-induced kidney tumorigenesis in male Syrian hamster. | Histochemistry and cell biology 20050101 |
| Morphine impairs host innate immune response and increases susceptibility to Streptococcus pneumoniae lung infection. | Journal of immunology (Baltimore, Md. : 1950) 20050101 |
| Characterisation of the advanced glycation endproduct receptor complex in the retinal pigment epithelium. | The British journal of ophthalmology 20050101 |
| Altered melanoma cell surface glycosylation mediates organ specific adhesion and metastasis via lectin receptors on the lung vascular endothelium. | Clinical & experimental metastasis 20050101 |
| Roles of galectin-3 in immune responses. | Archivum immunologiae et therapiae experimentalis 20050101 |
| Galectin-3/AGE-receptor 3 knockout mice show accelerated AGE-induced glomerular injury: evidence for a protective role of galectin-3 as an AGE receptor. | FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20041101 |
| Fluorescence polarization as an analytical tool to evaluate galectin-ligand interactions. | Analytical biochemistry 20041101 |
| Detection and molecular characterisation of thyroid cancer precursor lesions in a specific subset of Hashimoto's thyroiditis. | British journal of cancer 20040913 |
| Cell surface overexpression of galectin-3 and the presence of its ligand 90k in the blood plasma as determinants in colon neoplastic lesions. | Glycobiology 20040901 |
| Galectin-3 augments K-Ras activation and triggers a Ras signal that attenuates ERK but not phosphoinositide 3-kinase activity. | The Journal of biological chemistry 20040813 |
| Newcastle disease virus neuraminidase primes neutrophils for stimulation by galectin-3 and formyl-Met-Leu-Phe. | Experimental cell research 20040801 |
| LacdiNAc-glycans constitute a parasite pattern for galectin-3-mediated immune recognition. | Journal of immunology (Baltimore, Md. : 1950) 20040801 |
| Up-regulation of galectin-3 and its ligands by Trypanosoma cruzi infection with modulation of adhesion and migration of murine dendritic cells. | Glycobiology 20040701 |
| Lectin receptors for endometrial H-type 1 antigen on goat conceptuses. | American journal of reproductive immunology (New York, N.Y. : 1989) 20040701 |
| Hashimoto's thyroiditis with papillary thyroid carcinoma (PTC)-like nuclear alterations express molecular markers of PTC. | Histopathology 20040701 |
| Inhibition of N-(4-hydroxyphenyl)retinamide-induced apoptosis in breast cancer cells by galectin-3. | Cancer biology & therapy 20040501 |
| Mouse monoclonal IgA binds to the galectin-3/Mac-2 lectin from mouse macrophage cell lines. | Immunology letters 20040430 |
| Galectin-3: differential expression between small-cell and non-small-cell lung cancer. | Histopathology 20040401 |
| Galectin-3 precipitates as a pentamer with synthetic multivalent carbohydrates and forms heterogeneous cross-linked complexes. | The Journal of biological chemistry 20040319 |
| The negative regulator of Gli, Suppressor of fused (Sufu), interacts with SAP18, Galectin3 and other nuclear proteins. | The Biochemical journal 20040301 |
| Expression of galectin-3 in the rat pancreas during regeneration following hormone-induced pancreatitis. | Cell and tissue research 20040301 |
| Design of a multivalent galactoside ligand for selective targeting of HPMA copolymer-doxorubicin conjugates to human colon cancer cells. | European journal of cancer (Oxford, England : 1990) 20040101 |
| Mucins and mucin binding proteins in colorectal cancer. | Cancer metastasis reviews 20040101 |
| Expression of galectin-3 in neuronally differentiating PC12 cells is regulated both via Ras/MAPK-dependent and -independent signalling pathways. | Journal of neurochemistry 20031201 |
| Mechanisms involved in the stimulatory effect of advanced glycation end products on growth of rat aortic smooth muscle cells. | Metabolism: clinical and experimental 20031201 |
| CD29 and CD7 mediate galectin-3-induced type II T-cell apoptosis. | Cancer research 20031201 |
| Homodimeric galectin-7 (p53-induced gene 1) is a negative growth regulator for human neuroblastoma cells. | Oncogene 20030918 |
| Role of galectin-3 in diabetic nephropathy. | Journal of the American Society of Nephrology : JASN 20030801 |
| Reconstitution of galectin-3 alters glutathione content and potentiates TRAIL-induced cytotoxicity by dephosphorylation of Akt. | Experimental cell research 20030801 |
| Gene expression profiling of malignant mesothelioma. | Clinical cancer research : an official journal of the American Association for Cancer Research 20030801 |
| Common host genes are activated in mouse brain by Japanese encephalitis and rabies viruses. | The Journal of general virology 20030701 |
| Activated charcoal forms non-IgE binding complexes with peanut proteins. | The Journal of allergy and clinical immunology 20030701 |
| Galectin-3 expression in macrophages is signaled by Ras/MAP kinase pathway and up-regulated by modified lipoproteins. | Biochimica et biophysica acta 20030617 |
| Frequent downregulation of DMBT1 and galectin-3 in epithelial skin cancer. | International journal of cancer 20030610 |
| Lipid transfer protein 1 is a possible allergen in Arabidopsis thaliana. | International archives of allergy and immunology 20030601 |
| Malignant transformation of thyroid follicular cells by galectin-3. | Cancer letters 20030530 |
| Stimulation of proliferation of rat hepatic stellate cells by galectin-1 and galectin-3 through different intracellular signaling pathways. | The Journal of biological chemistry 20030523 |
| Potential roles of galectins in myeloid differentiation into three different lineages. | Journal of leukocyte biology 20030501 |
| Expression of liver-intestine cadherin and its possible interaction with galectin-3 in ductal adenocarcinoma of the pancreas. | Cancer science 20030501 |
| Conformational differences in liganded and unliganded states of Galectin-3. | Biochemistry 20030408 |
| Nuclear localization of Galectin-3 in transformed thyroid cells: a role in transcriptional regulation. | Biochemical and biophysical research communications 20030314 |
| Characterization of the levels of expression of retinoic acid receptors, galectin-3, macrophage migration inhibiting factor, and p53 in 51 adamantinomatous craniopharyngiomas. | Journal of neurosurgery 20030101 |
| Specificity of interactions of galectin-3 with Chrp, a cysteine- and histidine-rich cytoplasmic protein. | Biochimie 20030101 |
| Differential expression of galectin-3 in papillary projections of malignant and non-malignant hyperplastic thyroid lesions. | Acta chirurgica Iugoslavica 20030101 |
| Defining the glycophenotype of squamous epithelia using plant and mammalian lectins. Differentiation-dependent expression of alpha2,6- and alpha2,3-linked N-acetylneuraminic acid in squamous epithelia and carcinomas, and its differential effect on binding of the endogenous lectins galectins-1 and -3. | APMIS : acta pathologica, microbiologica, et immunologica Scandinavica 20021201 |
| Determination of galectin-3 messenger ribonucleic Acid overexpression in papillary thyroid cancer by quantitative reverse transcription-polymerase chain reaction. | The Journal of clinical endocrinology and metabolism 20021001 |
| Galectin-3 binds lactosaminylated lipooligosaccharides from Neisseria gonorrhoeae and is selectively expressed by mucosal epithelial cells that are infected. | Cellular microbiology 20021001 |
| Expression of human intestinal mucin is modulated by the beta-galactoside binding protein galectin-3 in colon cancer. | Gastroenterology 20020901 |
| Characterization of human CYP1A1/1A2 induction by DNA microarray and alpha-naphthoflavone. | Biochemical and biophysical research communications 20020809 |
| C-kit expression distinguishes salivary gland adenoid cystic carcinoma from polymorphous low-grade adenocarcinoma. | Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc 20020701 |
| Cross-reactivities between date palm (Phoenix dactylifera L.) polypeptides and foods implicated in the oral allergy syndrome. | Allergy 20020601 |
| Immunohistochemical expression of galectin-3 in benign and malignant thyroid lesions. | Archives of pathology & laboratory medicine 20020601 |
| Enhancement of IgE production in B cells by neutrophils via galectin-3 in IgE-associated atopic eczema/dermatitis syndrome. | International archives of allergy and immunology 20020601 |
| New alternatively spliced form of galectin-3, a member of the beta-galactoside-binding animal lectin family, contains a predicted transmembrane-spanning domain and a leucine zipper motif. | The Journal of biological chemistry 20020524 |
| Specific recognition and cleavage of galectin-3 by Leishmania major through species-specific polygalactose epitope. | The Journal of biological chemistry 20020517 |
| Galectin-3 translocates to the perinuclear membranes and inhibits cytochrome c release from the mitochondria. A role for synexin in galectin-3 translocation. | The Journal of biological chemistry 20020503 |
| Cubilin, a binding partner for galectin-3 in the murine utero-placental complex. | The Journal of biological chemistry 20020503 |
| Allergenic components of a novel food, Micronesian nut Nangai (Canarium indicum), shows IgE cross-reactivity in pollen allergic patients. | Allergy 20020501 |
| Galectin-3 modulates carbohydrate-dependent thymocyte interactions with the thymic microenvironment. | European journal of immunology 20020501 |
| Shuttling of galectin-3 between the nucleus and cytoplasm. | Glycobiology 20020501 |
| Activation of the neutrophil nicotinamide adenine dinucleotide phosphate oxidase by galectin-1. | Journal of immunology (Baltimore, Md. : 1950) 20020415 |
| Galectin-3: a biologic marker and diagnostic aid for chordoma. | Clinical orthopaedics and related research 20020401 |
| Galectin-3 phosphorylation is required for its anti-apoptotic function and cell cycle arrest. | The Journal of biological chemistry 20020301 |
| Low micromolar inhibitors of galectin-3 based on 3'-derivatization of N-acetyllactosamine. | Chembiochem : a European journal of chemical biology 20020301 |
| High-affinity binding of recombinant human galectin-4 to SO(3)(-)-->3Galbeta1-->3GalNAc pyranoside. | Glycobiology 20020301 |
| Determination of the affinity constants of recombinant human galectin-1 and -3 for simple saccharides by capillary affinophoresis. | Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20020225 |
| Role of galectin-3 as an adhesion molecule for neutrophil extravasation during streptococcal pneumonia. | Journal of immunology (Baltimore, Md. : 1950) 20020215 |
| Comparison of the crystal structures of the human manganese superoxide dismutase and the homologous Aspergillus fumigatus allergen at 2-A resolution. | Journal of immunology (Baltimore, Md. : 1950) 20020201 |
| Galectin-1 is overexpressed in nasal polyps under budesonide and inhibits eosinophil migration. | Laboratory investigation; a journal of technical methods and pathology 20020201 |
| The constitutive expression of galectin-3 is downregulated in the intestinal epithelia of Crohn's disease patients, and tumour necrosis factor alpha decreases the level of galectin-3-specific mRNA in HCT-8 cells. | European journal of gastroenterology & hepatology 20020201 |
| Cooperative interaction between interleukin 10 and galectin-3 against liver ischemia-reperfusion injury. | Clinical cancer research : an official journal of the American Association for Cancer Research 20020101 |
| Differentiation-dependent glycosylation of cells in squamous cell epithelia detected by a mammalian lectin. | Cells, tissues, organs 20020101 |
| Seeing strangers or announcing 'danger': galectin-3 in two models of innate immunity. | Glycoconjugate journal 20020101 |
| Galectin-3 mediates the endocytosis of beta-1 integrins by breast carcinoma cells. | Biochemical and biophysical research communications 20011214 |
| Distance mapping of protein-binding sites using spin-labeled oligosaccharide ligands. | Protein science : a publication of the Protein Society 20011101 |
| Role of galectin-3 in adenocarcinoma liver metastasis. | International journal of oncology 20011101 |
| Accelerated diabetic glomerulopathy in galectin-3/AGE receptor 3 knockout mice. | FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20011101 |
| Distinct ligand binding properties of Mac-2-binding protein and mouse cyclophilin [correction of mousephilin] C-associated protein. | European journal of immunology 20011001 |
| Isolation and characterization of galectins in the mammalian retina. | Investigative ophthalmology & visual science 20010901 |
| Detection of macrophage migration inhibitory factor (MIF) in human cholesteatomas and functional implications of correlations to recurrence status and to expression of matrix metalloproteinases-3/9, retinoic acid receptor-beta, and anti-apoptotic galectin-3. | The Laryngoscope 20010901 |
| Thermodynamic analysis of the binding of galactose and poly-N-acetyllactosamine derivatives to human galectin-3. | FEBS letters 20010629 |
| The levels of retinoid RARbeta receptors correlate with galectin-1, -3 and -8 expression in human cholesteatomas. | Hearing research 20010601 |
| Application of an immunodiagnostic method for improving preoperative diagnosis of nodular thyroid lesions. | Lancet (London, England) 20010526 |
| [Expression of galectin-3 in thyroid gland and follicular cell tumors of the thyroid. A critical study of its possible role in preoperative differential diagnosis]. | Der Pathologe 20010501 |
| NMR solution studies of hamster galectin-3 and electron microscopic visualization of surface-adsorbed complexes: evidence for interactions between the N- and C-terminal domains. | Biochemistry 20010417 |
| Expression and function of galectin-3, a beta-galactoside-binding protein in activated T lymphocytes. | Journal of leukocyte biology 20010401 |
| Rapid release of intracellular galectin-3 from breast carcinoma cells by fetuin. | Cancer research 20010301 |
| Negative regulation of T-cell activation and autoimmunity by Mgat5 N-glycosylation. | Nature 20010208 |
| Simultaneous induction of galectin-3 phosphorylated on tyrosine residue, p21(WAF1/Cip1/Sdi1), and the proliferating cell nuclear antigen at a distinctive period of repair of hepatocytes injured by CCl4. | Biochemical and biophysical research communications 20010202 |
| Glycoprotein 90K/MAC-2BP interacts with galectin-1 and mediates galectin-1-induced cell aggregation. | International journal of cancer 20010115 |
| Uncoupling of chondrocyte death and vascular invasion in mouse galectin 3 null mutant bones. | Developmental biology 20010101 |
| MP20, the second most abundant lens membrane protein and member of the tetraspanin superfamily, joins the list of ligands of galectin-3. | BMC cell biology 20010101 |
| Differential reactivity for galectin-3 in Hürthle cell adenomas and carcinomas. | Endocrine pathology 20010101 |
| Galectins and other endogenous carbohydrate-binding proteins of animal bladder. | Advances in experimental medicine and biology 20010101 |
| Efficacy of galectins in the amelioration of nephrotoxic serum nephritis in Wistar Kyoto rats. | Kidney international 20001101 |
| Up-regulation of galectin-3 in acute renal failure of the rat. | The American journal of pathology 20000901 |
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