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10213-10-2

10213-10-2 | Tungstate (WO42-), disodium, dihydrate, (T-4)- (9CI)

CAS No: 10213-10-2 Catalog No: AG0006Q2 MDL No:MFCD00149190

Product Description

Catalog Number:
AG0006Q2
Chemical Name:
Tungstate (WO42-), disodium, dihydrate, (T-4)- (9CI)
CAS Number:
10213-10-2
Molecular Formula:
H4Na2O6W
Molecular Weight:
329.8477
MDL Number:
MFCD00149190
IUPAC Name:
disodium;dioxido(dioxo)tungsten;dihydrate
InChI:
InChI=1S/2Na.2H2O.4O.W/h;;2*1H2;;;;;/q2*+1;;;;;2*-1;
InChI Key:
WPZFLQRLSGVIAA-UHFFFAOYSA-N
SMILES:
[O-][W](=O)(=O)[O-].[Na+].[Na+].O.O
EC Number:
600-275-2
UNII:
X1F4NY6U13

Properties

Complexity:
62.2  
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
5  
Defined Atom Stereocenter Count:
0
Defined Bond Stereocenter Count:
0
Exact Mass:
329.931g/mol
Formal Charge:
0
Heavy Atom Count:
9  
Hydrogen Bond Acceptor Count:
6  
Hydrogen Bond Donor Count:
2  
Isotope Atom Count:
0
Molecular Weight:
329.846g/mol
Monoisotopic Mass:
329.931g/mol
Rotatable Bond Count:
0
Topological Polar Surface Area:
82.3A^2
Undefined Atom Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0

Literature

Title Journal
Tungsten targets the tumor microenvironment to enhance breast cancer metastasis. Toxicological sciences : an official journal of the Society of Toxicology 20150101
Sodium tungstate administration ameliorated diabetes-induced electrical and contractile remodeling of rat heart without normalization of hyperglycemia. Biological trace element research 20120801
Exposure to sodium tungstate and Respiratory Syncytial Virus results in hematological/immunological disease in C57BL/6J mice. Chemico-biological interactions 20120405
Anti-diabetic and anti-obesity agent sodium tungstate enhances GCN pathway activation through Glc7p inhibition. FEBS letters 20120203
Calcium is involved in nitric oxide- and auxin-induced lateral root formation in rice. Protoplasma 20120101
[Influence of environmental factors on the generation of nitric oxide in the roots of etiolated pea seedlings]. Prikladnaia biokhimiia i mikrobiologiia 20120101
Anti-obesity sodium tungstate treatment triggers axonal and glial plasticity in hypothalamic feeding centers. PloS one 20120101
Efficient degradation of methabenzthiazuron photoinduced by decatungstate anion in water: kinetics and mechanistic studies. Chemosphere 20111001
The potential reproductive, neurobehavioral and systemic effects of soluble sodium tungstate exposure in Sprague-Dawley rats. Toxicology and applied pharmacology 20110715
Biospeciation of tungsten in the serum of diabetic and healthy rats treated with the antidiabetic agent sodium tungstate. Talanta 20110530
Novel inducers of the envelope stress response BaeSR in Salmonella Typhimurium: BaeR is critically required for tungstate waste disposal. PloS one 20110101
Proof-of-concept trial on the efficacy of sodium tungstate in human obesity. Diabetes, obesity & metabolism 20101101
Sodium tungstate attenuate oxidative stress in brain tissue of streptozotocin-induced diabetic rats. Biological trace element research 20100801
Mycorrhization of the notabilis and sitiens tomato mutants in relation to abscisic acid and ethylene contents. Journal of plant physiology 20100515
Sodium tungstate (Na2WO4) exposure increases apoptosis in human peripheral blood lymphocytes. Journal of immunotoxicology 20100101
Sodium tungstate and vanadyl sulfate effects on blood pressure and vascular prostanoids production in fructose-overloaded rats. Clinical and experimental hypertension (New York, N.Y. : 1993) 20100101
Nitric oxide production occurs downstream of reactive oxygen species in guard cells during stomatal closure induced by chitosan in abaxial epidermis of Pisum sativum. Planta 20090301
Sodium tungstate on some biochemical parameters of the parotid salivary gland of streptozotocin-induced diabetic rats: a short-term study. Biological trace element research 20090201
Molecular mechanisms of tungstate-induced pancreatic plasticity: a transcriptomics approach. BMC genomics 20090101
A quantitative study of sodium tungstate protective effect on pancreatic beta cells in streptozotocin-induced diabetic rats. Micron (Oxford, England : 1993) 20081201
Ischemia-reperfusion injury in rats affects hydraulic conductivity in two phases that are temporally and mechanistically separate. American journal of physiology. Heart and circulatory physiology 20081101
Sodium tungstate decreases sucrase and Na+/D-glucose cotransporter in the jejunum of diabetic rats. American journal of physiology. Gastrointestinal and liver physiology 20080901
[Effect of sodium tungstate on glucose metabolism in adipocytes]. Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences 20080801
The glucose-lowering agent sodium tungstate increases the levels and translocation of GLUT4 in L6 myotubes through a mechanism associated with ERK1/2 and MEF2D. Diabetologia 20080701
Beta cell protective effects of sodium tungstate in streptozotocin-induced diabetic rats: glycemic control, blockage of oxidative stress and beta cell histochemistry. Iranian biomedical journal 20080701
Effects of sulphite supplementation on vascular responsiveness in sulphite oxidase-deficient rats. Clinical and experimental pharmacology & physiology 20080301
Enzymatic activities in brains of diabetic rats treated with vanadyl sulphate and sodium tungstate. Acta physiologica Hungarica 20071201
Tungstate administration improves the sexual and reproductive function in female rats with streptozotocin-induced diabetes. Human reproduction (Oxford, England) 20070801
Reversed type of color-pattern modifications of butterfly wings: a physiological mechanism of wing-wide color-pattern determination. Journal of insect physiology 20070601
Tetraalkylphosphonium polyoxometalate ionic liquids: novel, organic-inorganic hybrid materials. The journal of physical chemistry. B 20070510
Protective effects of tungstophosphoric acid and sodium tungstate on chemically induced liver necrosis in wistar rats. Journal of pharmacy & pharmaceutical sciences : a publication of the Canadian Society for Pharmaceutical Sciences, Societe canadienne des sciences pharmaceutiques 20070101
Tungstate sulfuric acid (TSA)/KMnO4 as a novel heterogeneous system for rapid deoximation. Molecules (Basel, Switzerland) 20060928
Simple and rapid determination of hydrogen peroxide using phosphine-based fluorescent reagents with sodium tungstate dihydrate. Analytical sciences : the international journal of the Japan Society for Analytical Chemistry 20060601
Intestinal mucosal alterations in rats with carbon tetrachloride-induced cirrhosis: changes in glycosylation and luminal bacteria. Hepatology (Baltimore, Md.) 20060401
Sodium tungstate decreases the phosphorylation of tau through GSK3 inactivation. Journal of neuroscience research 20060201
Molecular and multidimensional polyoxotungstates functionalized by {Cu(bpy)}2+ groups. Dalton transactions (Cambridge, England : 2003) 20051221
Improved absorption of caseinophosphopeptide-bound iron: role of alkaline phosphatase. The Journal of nutritional biochemistry 20050701
Oral administration of sodium tungstate improves cardiac performance in streptozotocin-induced diabetic rats. Canadian journal of physiology and pharmacology 20050501
Tungstate treatment improves Leydig cell function in streptozotocin-diabetic rats. Journal of andrology 20050101
Oxidative stress contributes to methotrexate-induced small intestinal toxicity in rats. Scandinavian journal of gastroenterology 20041101
Differential effects of sodium tungstate and vanadyl sulfate on vascular responsiveness to vasoactive agents and insulin sensitivity in fructose-fed rats. Canadian journal of physiology and pharmacology 20041001
Liver necrosis and fulminant hepatic failure in rats: protection by oxyanionic form of tungsten. Biochimica et biophysica acta 20040405
The antidiabetic agent sodium tungstate activates glycogen synthesis through an insulin receptor-independent pathway. The Journal of biological chemistry 20031031
Modulation of glucose transporters in rat diaphragm by sodium tungstate. FEBS letters 20030508
Effect of somatostatin on cholecystokinin-induced amylase release in rat pancreatic acini. Pancreas 20010701

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