200,000+ products from a single source!
sales@angenechem.com
CAS No: 10159-53-2 Catalog No: AG0004XJ MDL No:
Title | Journal |
---|---|
Phosphoramide mustard induces autophagy markers and mTOR inhibition prevents follicle loss due to phosphoramide mustard exposure. | Reproductive toxicology (Elmsford, N.Y.) 20170101 |
The ovarian DNA damage repair response is induced prior to phosphoramide mustard-induced follicle depletion, and ataxia telangiectasia mutated inhibition prevents PM-induced follicle depletion. | Toxicology and applied pharmacology 20160201 |
Phosphoramide mustard exposure induces DNA adduct formation and the DNA damage repair response in rat ovarian granulosa cells. | Toxicology and applied pharmacology 20150201 |
Ovarian xenobiotic biotransformation enzymes are altered during phosphoramide mustard-induced ovotoxicity. | Toxicological sciences : an official journal of the Society of Toxicology 20141001 |
Anticancer system created by acrolein and hydroxyl radical generated in enzymatic oxidation of spermine and other biochemical reactions. | Medical hypotheses 20121001 |
Detection of DNA damage in oocytes of small ovarian follicles following phosphoramide mustard exposures of cultured rodent ovaries in vitro. | Toxicology and applied pharmacology 20110601 |
Phenylalanyl-aminocyclophosphamides as model prodrugs for proteolytic activation: synthesis, stability, and stereochemical requirements for enzymatic cleavage. | Bioorganic & medicinal chemistry letters 20070115 |
Pharmacokinetics of N-2-chloroethylaziridine, a volatile cytotoxic metabolite of cyclophosphamide, in the rat. | Cancer chemotherapy and pharmacology 20061001 |
Characterizing the ovotoxicity of cyclophosphamide metabolites on cultured mouse ovaries. | Toxicological sciences : an official journal of the Society of Toxicology 20060401 |
Population pharmacokinetics of cyclophosphamide and its metabolites 4-hydroxycyclophosphamide, 2-dechloroethylcyclophosphamide, and phosphoramide mustard in a high-dose combination with Thiotepa and Carboplatin. | Therapeutic drug monitoring 20051201 |
Mechanisms of resistance against cyclophosphamide and ifosfamide: can they be overcome without sacrificing selectivity? | Cancer treatment and research 20020101 |
Effect of O6-benzylguanine on nitrogen mustard-induced toxicity, apoptosis, and mutagenicity in Chinese hamster ovary cells. | Molecular cancer therapeutics 20011101 |
A mechanism-based pharmacokinetic model for the cytochrome P450 drug-drug interaction between cyclophosphamide and thioTEPA and the autoinduction of cyclophosphamide. | Journal of pharmacokinetics and pharmacodynamics 20010601 |
Characterization of a human cell clone expressing cytochrome P450 for safe use in human somatic cell therapy. | Annals of the New York Academy of Sciences 19990630 |
Injection of encapsulated cells producing an ifosfamide-activating cytochrome P450 for targeted chemotherapy to pancreatic tumors. | Annals of the New York Academy of Sciences 19990630 |
Intratumoral injection of encapsulated cells producing an oxazaphosphorine activating cytochrome P450 for targeted chemotherapy. | Advances in experimental medicine and biology 19980101 |
De novo expression of transfected human class 1 aldehyde dehydrogenase (ALDH) causes resistance to oxazaphosphorine anti-cancer alkylating agents in hamster V79 cell lines. Elevated class 1 ALDH activity is closely correlated with reduction in DNA interstrand cross-linking and lethality. | The Journal of biological chemistry 19960517 |
Studies on the urotoxicity of oxazaphosphorine cytostatics and its prevention--I. Experimental studies on the urotoxicity of alkylating compounds. | European journal of cancer 19810601 |
© 2019 Angene International Limited. All rights Reserved.