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101-26-8 | 3-(Dimethylcarbamoyloxy)-1-Methylpyridinium Bromide
CAS No: 101-26-8 Catalog No: AG0033GW MDL No:MFCD00079283
Product Description
Catalog Number:
AG0033GW
Chemical Name:
3-(Dimethylcarbamoyloxy)-1-Methylpyridinium Bromide
CAS Number:
101-26-8
Molecular Formula:
C9H13BrN2O2
Molecular Weight:
261.1157
MDL Number:
MFCD00079283
IUPAC Name:
(1-methylpyridin-1-ium-3-yl) N,N-dimethylcarbamate;bromide
InChI:
InChI=1S/C9H13N2O2.BrH/c1-10(2)9(12)13-8-5-4-6-11(3)7-8;/h4-7H,1-3H3;1H/q+1;/p-1
InChI Key:
VNYBTNPBYXSMOO-UHFFFAOYSA-M
SMILES:
C[n+]1cccc(c1)OC(=O)N(C)C.[Br-]
EC Number:
202-929-9
UNII:
KVI301NA53
Properties
Complexity:
183
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
2
Defined Atom Stereocenter Count:
0
Defined Bond Stereocenter Count:
0
Exact Mass:
260.016g/mol
Formal Charge:
0
Heavy Atom Count:
14
Hydrogen Bond Acceptor Count:
3
Hydrogen Bond Donor Count:
0
Isotope Atom Count:
0
Molecular Weight:
261.119g/mol
Monoisotopic Mass:
260.016g/mol
Rotatable Bond Count:
2
Topological Polar Surface Area:
33.4A^2
Undefined Atom Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
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| Effective countermeasure against poisoning by organophosphorus insecticides and nerve agents. | Proceedings of the National Academy of Sciences of the United States of America 20060829 |
| Eosinophilia, myositis, and myasthenia gravis associated with a thymoma. | Muscle & nerve 20060801 |
| The 'slurp' test: bedside evaluation of bulbar muscle fatigue. | Pediatrics 20060801 |
| Pyridostigmine in autonomic failure: can we treat postural hypotension and bladder dysfunction with one drug? | Clinical autonomic research : official journal of the Clinical Autonomic Research Society 20060801 |
| Kinetic analysis of the protection afforded by reversible inhibitors against irreversible inhibition of acetylcholinesterase by highly toxic organophosphorus compounds. | Biochemical pharmacology 20060728 |
| Available treatment options for the management of Lambert-Eaton myasthenic syndrome. | Expert opinion on pharmacotherapy 20060701 |
| Neuromyotonia and myasthenia gravis in the absence of thymoma. | European journal of neurology 20060701 |
| Cholinergic overstimulation supports conditioned-facilitated startle but not conditioned hyperalgesia. | Pharmacology, biochemistry, and behavior 20060701 |
| Multiple vaccine and pyridostigmine interactions: effects on cognition, muscle function and health outcomes in marmosets. | Pharmacology, biochemistry, and behavior 20060601 |
| Dysphonia as first symptom of late-onset myasthenia gravis. | Journal of general internal medicine 20060601 |
| Vincristine induced cranial polyneuropathy. | Indian journal of pediatrics 20060601 |
| Multiple vaccine and pyridostigmine interactions: effects on EEG and sleep in the common marmoset. | Pharmacology, biochemistry, and behavior 20060601 |
| [Myasthenia gravis and hyperthyroidism: two cases]. | Annales d'endocrinologie 20060601 |
| Residual wires and autonomic failure treatment. | Clinical autonomic research : official journal of the Clinical Autonomic Research Society 20060601 |
| Microsphere-based protease assays and screening application for lethal factor and factor Xa. | Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501 |
| Interaction of pyridostigmine bromide and N,N-diethyl-m-toluamide alone and in combination with P-glycoprotein expressed in Escherichia coli leaky mutant. | Journal of toxicology and environmental health. Part A 20060501 |
| Myasthenia gravis accompanied with hypokalemic periodic paralysis. | Journal of the Medical Association of Thailand = Chotmaihet thangphaet 20060501 |
| Pyridostigmine treatment trial in neurogenic orthostatic hypotension. | Archives of neurology 20060401 |
| Fetal exposure to 3,4-diaminopyridine in a pregnant woman with congenital myasthenia syndrome. | The Annals of pharmacotherapy 20060401 |
| Acetylcholinesterase inhibition and orthostatic hypotension. | Clinical autonomic research : official journal of the Clinical Autonomic Research Society 20060401 |
| Childhood sexual abuse in relation to neurobiological challenge tests in patients with borderline personality disorder and normal controls. | Psychiatry research 20060330 |
| Pyridostigmine reduces QTc interval during recovery from maximal exercise in ischemic heart disease. | International journal of cardiology 20060208 |
| [Stopping smoking and constipation]. | Presse medicale (Paris, France : 1983) 20060201 |
| Bifunctional compounds eliciting anti-inflammatory and anti-cholinesterase activity as potential treatment of nerve and blister chemical agents poisoning. | Journal of applied toxicology : JAT 20060101 |
| [Ocular involvement in MuSK antibody-positive myasthenia gravis]. | Klinische Monatsblatter fur Augenheilkunde 20060101 |
| Rapid determination of N,N-diethyl-m-toluamide and permethrin in human plasma by gas chromatography-mass spectrometry and pyridostigmine bromide by high-performance liquid chromatography. | Journal of analytical toxicology 20060101 |
| Determination of pyridostigmine bromide and its metabolites in biological samples. | Journal of pharmacy & pharmaceutical sciences : a publication of the Canadian Society for Pharmaceutical Sciences, Societe canadienne des sciences pharmaceutiques 20060101 |
| Circadian rhythms of heart rate and locomotion after treatment with low-dose acetylcholinesterase inhibitors. | Journal of applied toxicology : JAT 20060101 |
| Myasthenia gravis disclosed by lithium carbonate. | The Journal of neuropsychiatry and clinical neurosciences 20060101 |
| Intestinal pseudo-obstruction as initial presentation of thymoma. | Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology 20060101 |
| Acetylcholinesterase inhibition affects cardiovascular structure in mice. | Physiological research 20060101 |
| Oral administration of pyridostigmine bromide and huperzine A protects human whole blood cholinesterases from ex vivo exposure to soman. | Chemico-biological interactions 20051215 |
| Bioscavengers for the protection of humans against organophosphate toxicity. | Chemico-biological interactions 20051215 |
| Inhibition of guinea pig hemi-diaphragm acetylcholinesterase activity by pyridostigmine bromide and protection against soman toxicity. | Chemico-biological interactions 20051215 |
| An ex vivo approach for the evaluation of reversible inhibitors as potential pretreatments against organophosphate toxicity. | Chemico-biological interactions 20051215 |
| Pyridostigmine in the treatment of orthostatic hypotension. | Clinical autonomic research : official journal of the Clinical Autonomic Research Society 20051201 |
| Nonresponsiveness to anticholinesterase agents in patients with MuSK-antibody-positive MG. | Neurology 20051108 |
| Pioglitazone treatment increases spontaneous growth hormone (GH) secretion and stimulated GH levels in polycystic ovary syndrome. | The Journal of clinical endocrinology and metabolism 20051001 |
| Ocular motor dysfunction and ptosis in ocular myasthenia gravis: effects of treatment. | The British journal of ophthalmology 20051001 |
| An elderly man with dysphagia and dysarthria. | Indian journal of medical sciences 20051001 |
| Coronary vasospasm secondary to hypercholinergic crisis: an iatrogenic cause of acute myocardial infarction in myasthenia gravis. | International journal of cardiology 20050901 |
| Primary CNS lymphoma complicating treatment of myasthenia gravis with mycophenolate mofetil. | Neurology 20050823 |
| Mild interoceptive stressors affect learning and reactivity to contextual cues: toward understanding the development of unexplained illnesses. | Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20050801 |
| Acetylcholinesterase inhibition improves tachycardia in postural tachycardia syndrome. | Circulation 20050531 |
| Evaluation of GH reserve in patients with adrenal incidentalomas and biochemical evidence of subclinical autonomous glucocorticoid hypersecretion. | Clinical endocrinology 20050501 |
| Vaccination alone or in combination with pyridostigmine promotes and prolongs activation of stress-activated kinases induced by stress in the mouse brain. | Journal of neurochemistry 20050501 |
| Off-label administration of drugs to healthy military personnel. Dubious ethics of preventive measures. | Journal of medical ethics 20050501 |
| Low-dose cholinesterase inhibitors do not induce delayed effects on cerebral blood flow and metabolism. | Pharmacology, biochemistry, and behavior 20050401 |
| Treatment counters low blood pressure upon standing. | Mayo Clinic health letter (English ed.) 20050401 |
| Bifunctional compounds eliciting both anti-inflammatory and cholinergic activity as potential drugs for neuroinflammatory impairments. | Neuroscience letters 20050307 |
| A T-cell-dependent humoral immune response is preserved during the administration of the nerve agent pre-treatment pyridostigmine bromide in a murine model. | International immunopharmacology 20050301 |
| Pharmacologic prophylaxis against nerve agent poisoning. | The Israel Medical Association journal : IMAJ 20050301 |
| Peripheral ChE inhibition modulates brain monoamines levels and c-fos oncogene in mice subjected to a stress situation. | Neurochemical research 20050301 |
| Myasthenia gravis and a rare complication of chemotherapy. | The Medical journal of Australia 20050207 |
| The anti-inflammatory and cholinesterase inhibitor bifunctional compound IBU-PO protects from beta-amyloid neurotoxicity by acting on Wnt signaling components. | Neurobiology of disease 20050201 |
| Pyridostigmine for treatment of neurogenic orthostatic hypotension [correction of hypertension]--a follow-up survey study. | Clinical autonomic research : official journal of the Clinical Autonomic Research Society 20050201 |
| Do vasoactive neuropeptide autoimmune disorders explain pyridostigmine's association with Gulf War syndrome? | Medical hypotheses 20050101 |
| Diagnosis of growth hormone deficiency. | Frontiers of hormone research 20050101 |
| [The influence of aminostigmine on the parameters of nonspecific resistance and immune system of the organism upon acute poisoning of benzyl 3-quinuclidylate]. | Eksperimental'naia i klinicheskaia farmakologiia 20050101 |
| Old legacies and new paradigms: confusing 'research' and 'treatment' and its consequences in responding to emergent health threats. | Journal of health care law & policy 20050101 |
| Statin-associated exacerbation of myasthenia gravis. | Neurology 20041214 |
| Cardiac responses of Pacific oyster Crassostrea gigas to agents modulating cholinergic function. | Comparative biochemistry and physiology. Toxicology & pharmacology : CBP 20041201 |
| New treatment eyed for low blood pressure. | Harvard heart letter : from Harvard Medical School 20041201 |
| An in vitro investigation of the effects of the nerve agent pretreatment pyridostigmine bromide on human peripheral blood T-cell function. | International immunopharmacology 20041101 |
| Cholinergic stimulation with pyridostigmine protects against exercise induced myocardial ischaemia. | Heart (British Cardiac Society) 20041001 |
| Response of myasthenia gravis to rituximab in a patient with non-Hodgkin lymphoma. | American journal of hematology 20041001 |
| Facile synthesis and initial PET imaging of novel potential heart acetylcholinesterase imaging agents [11C]pyridostigmine and its analogs. | Nuclear medicine and biology 20041001 |
| Minimally invasive gastric bypass in a morbidly obese patient with myasthenia gravis. | Obesity surgery 20041001 |
| Early and late reversal of rocuronium with pyridostigmine during sevoflurane anaesthesia in children. | Anaesthesia and intensive care 20041001 |
| Pulmonary metastasis 12 years after resection of thymoma with microscopic capsule invasion. | Japanese journal of clinical oncology 20041001 |
| The cholinergic system controls ghrelin release and ghrelin-induced growth hormone release in humans. | The Journal of clinical endocrinology and metabolism 20040901 |
| Sick veterans pin hopes on Gulf War inquiry. | Nature 20040819 |
| Enhanced heart rate variability and baroreflex index after stress and cholinesterase inhibition in mice. | American journal of physiology. Heart and circulatory physiology 20040701 |
| Cholinergic stimulation with pyridostigmine increases heart rate variability and baroreflex sensitivity in rats. | Autonomic neuroscience : basic & clinical 20040630 |
| Distinct phenotypes of congenital acetylcholine receptor deficiency. | Neuromuscular disorders : NMD 20040601 |
| Acetylcholine regulates ghrelin secretion in humans. | The Journal of clinical endocrinology and metabolism 20040501 |
| Therapy for nerve agent poisoning. | Archives of neurology 20040501 |
| Interactive effects of paraoxon and pyridostigmine on blood-brain barrier integrity and cholinergic toxicity. | Toxicological sciences : an official journal of the Society of Toxicology 20040401 |
| [Acute respiratory failure that needs mechanical ventilation: first manifestation of myasthenia gravis]. | Anales de medicina interna (Madrid, Spain : 1984) 20040401 |
| Persistent/delayed toxic effects of low-dose sarin and pyridostigmine under physical stress (exercise) in mice. | Indian journal of physiology and pharmacology 20040401 |
| Joint pain and hyperalgesia due to pyridostigmine bromide in a patient with myasthenia gravis. | Neurology 20040309 |
| Treatment of vincristine-induced bilateral ptosis with pyridoxine and pyridostigmine. | Pediatric blood & cancer 20040301 |
| Assessment of GH reserve before and after successful treatment of adult patients with Cushing's syndrome. | Clinical endocrinology 20040301 |
| Pemphigus vulgaris acantholysis ameliorated by cholinergic agonists. | Archives of dermatology 20040301 |
| Congenital myasthenic syndrome: presentation, electrodiagnosis, and muscle biopsy. | Journal of child neurology 20040301 |
| Acute experimental tabun-induced intoxication and its therapy in rats. | Central European journal of public health 20040301 |
| Does early treatment of ocular myasthenia gravis with prednisone reduce progression to generalized disease? | Journal of the neurological sciences 20040215 |
| The effect of prednisone on the progression from ocular to generalized myasthenia gravis. | Journal of the neurological sciences 20040215 |
| Co-exposure to pyridostigmine bromide, DEET, and/or permethrin causes sensorimotor deficit and alterations in brain acetylcholinesterase activity. | Pharmacology, biochemistry, and behavior 20040201 |
| Lambert-Eaton myasthenic syndrome. | Revue neurologique 20040201 |
| Effects of fosphenytoin on nerve agent-induced status epilepticus. | Drug and chemical toxicology 20040201 |
| Pyridostigmine bromide (PYR) alters immune function in B6C3F1 mice. | Immunopharmacology and immunotoxicology 20040201 |
| Stress and combined exposure to low doses of pyridostigmine bromide, DEET, and permethrin produce neurochemical and neuropathological alterations in cerebral cortex, hippocampus, and cerebellum. | Journal of toxicology and environmental health. Part A 20040123 |
| Neurobiological correlates of diagnosis and underlying traits in patients with borderline personality disorder compared with normal controls. | Psychiatry research 20040101 |
| Low-level exposure of guinea pigs and marmosets to sarin vapour in air: lowest-observable-adverse-effect level (LOAEL) for miosis. | Journal of applied toxicology : JAT 20040101 |
| New approaches to the treatment of pemphigus. | The journal of investigative dermatology. Symposium proceedings 20040101 |
| Acute neuromuscular failure related to long-term botulinum toxin therapy. | European neurology 20040101 |
| Myasthenia gravis: an unusual cause of diplopia in polymyalgia rheumatica. | Clinical and experimental rheumatology 20040101 |
| Low levels of sarin affect the EEG in marmoset monkeys: a pilot study. | Journal of applied toxicology : JAT 20040101 |
| Pyridostigmine in postpolio syndrome: no decline in fatigue and limited functional improvement. | Journal of neurology, neurosurgery, and psychiatry 20031201 |
| Development and validation of a liquid chromatography-tandem mass spectrometry method for the determination of pyridostigmine bromide from guinea pig plasma. | Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20031105 |
| Effects of daily stress or repeated paraoxon exposures on subacute pyridostigmine toxicity in rats. | Archives of toxicology 20031001 |
| Acetylcholinesterase inhibition in the treatment of hypotension. | Journal of neurology, neurosurgery, and psychiatry 20030901 |
| Acetylcholinesterase inhibition: a novel approach in the treatment of neurogenic orthostatic hypotension. | Journal of neurology, neurosurgery, and psychiatry 20030901 |
| Heart rate variability in chronic heart failure: target for therapy? | American heart journal 20030901 |
| Cholinergic stimulation with pyridostigmine reduces ventricular arrhythmia and enhances heart rate variability in heart failure. | American heart journal 20030901 |
| Unilateral headache due to myasthenia gravis. | Cephalalgia : an international journal of headache 20030901 |
| Combined forced running stress and subclinical paraoxon exposure have little effect on pyridostigmine-induced acute toxicity in rats. | Toxicology 20030828 |
| Cardiac function during mental stress: cholinergic modulation with pyridostigmine in healthy subjects. | Clinical science (London, England : 1979) 20030801 |
| Acetylcholinesterase inhibition with pyridostigmine improves heart rate recovery after maximal exercise in patients with chronic heart failure. | Heart (British Cardiac Society) 20030801 |
| Childhood ocular myasthenia gravis. | Ophthalmology 20030701 |
| Comparative efficacy of diazepam and avizafone against sarin-induced neuropathology and respiratory failure in guinea pigs: influence of atropine dose. | Toxicology 20030630 |
| Gulf War syndrome revisited. | EMBO reports 20030601 |
| Controlled intermittent asystole cardiac therapy induced by pharmacologically potentiated vagus nerve stimulation in normal and hibernating myocardium. | The Annals of thoracic surgery 20030601 |
| Myasthenia gravis and masticatory muscle myositis in a dog. | The Canadian veterinary journal = La revue veterinaire canadienne 20030601 |
| Parkinson's disease associated with myasthenia gravis. A report of 4 cases. | Journal of neurology 20030601 |
| Prolonged treatment with glycerophosphocholine, an acetylcholine precursor, does not disclose the potentiating effect of cholinesterase inhibitors on GHRH-induced somatotroph secretion in anorexia nervosa. | Journal of endocrinological investigation 20030601 |
| Stress interacts with peripheral cholinesterase inhibitors to cause central nervous system effects. | Life sciences 20030523 |
| Take your pyridostigmine: that's an (ethical?) order! | The Lancet. Neurology 20030501 |
| Control of nerve agent-induced seizures is critical for neuroprotection and survival. | Toxicology and applied pharmacology 20030415 |
| Re-assessment of growth hormone secretion in young adult patients with childhood-onset growth hormone deficiency. | Clinical endocrinology 20030401 |
| Changes in respiratory condition after thymectomy for patients with myasthenia gravis. | Annals of thoracic and cardiovascular surgery : official journal of the Association of Thoracic and Cardiovascular Surgeons of Asia 20030401 |
| Neuroprotective efficacy of pharmacological pretreatment and antidotal treatment in tabun-poisoned rats. | Toxicology 20030314 |
| Clinical trials. New rule triggers debate over best way to test drugs. | Science (New York, N.Y.) 20030314 |
| Thymectomy in ocular myasthenia gravis. | The Journal of thoracic and cardiovascular surgery 20030301 |
| Effect of chronic pyridostigmine bromide treatment on cardiovascular and behavioral parameters in mice. | Pharmacology, biochemistry, and behavior 20030301 |
| Pyridostigmine bromide modulates topical irritant-induced cytokine release from human epidermal keratinocytes and isolated perfused porcine skin. | Toxicology 20030201 |
| [Ogilvie's syndrome: a rare cause of the acute abdomen]. | Zeitschrift fur Gastroenterologie 20030201 |
| Pyridostigmine enhances glutamatergic transmission in hippocampal CA1 neurons. | Experimental neurology 20030201 |
| Impact of growth hormone on central nervous activity, vigilance, and tiredness after short-term therapy in growth hormone-deficient adults. | Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme 20030201 |
| Percutaneous absorption of topical N,N-diethyl-m-toluamide (DEET): effects of exposure variables and coadministered toxicants. | Journal of toxicology and environmental health. Part A 20030124 |
| Testicular germ-cell apoptosis in stressed rats following combined exposure to pyridostigmine bromide, N,N-diethyl m-toluamide (DEET), and permethrin. | Journal of toxicology and environmental health. Part A 20030110 |
| Effects of long-term estrogen replacement therapy on growth hormone response to pyridostigmine in healthy postmenopausal women. | Psychoneuroendocrinology 20030101 |
| Low concentrations of pyridostigmine prevent soman-induced inhibition of GABAergic transmission in the central nervous system: involvement of muscarinic receptors. | The Journal of pharmacology and experimental therapeutics 20030101 |
| Acetylcholine does not play a major role in mediating the endocrine responses to ghrelin, a natural ligand of the GH secretagogue receptor, in humans. | Clinical endocrinology 20030101 |
| Pyridostigmine for fibromyalgia: comment on the article by Paiva and a historical vignette. | Arthritis and rheumatism 20030101 |
| Thymectomy in nonthymoma early-onset myasthenia gravis in correlation with disease severity and muscle autoantibodies. | European neurology 20030101 |
| Double trouble. | Survey of ophthalmology 20030101 |
| Heightening awareness of myasthenia gravis, its presentation, symptoms and new treatments that are now available. | Journal of the Irish Dental Association 20030101 |
| A comparison of the neuroprotective efficacy of pharmacological pretreatment and antidotal treatment in soman-poisoned rats. | Acta medica (Hradec Kralove) 20030101 |
| Effect of methoxime combined with anticholinergic, anticonvulsant or anti-HCN drugs in tabun-poisoned mice. | Acta medica (Hradec Kralove) 20030101 |
| The effect of use of pyridostigmine and requirement of vecuronium in patients with myasthenia gravis. | Journal of postgraduate medicine 20030101 |
| A typical case of Myasthenia Gravis. | Kathmandu University medical journal (KUMJ) 20030101 |
| Intravenous immunoglobulin monotherapy in long-term treatment of myasthenia gravis. | Clinical neurology and neurosurgery 20021201 |
| Residual paralysis induced by either vecuronium or rocuronium after reversal with pyridostigmine. | Anesthesia and analgesia 20021201 |
| Autosomal recessive limb girdle myasthenia in two sisters. | Neurology India 20021201 |
| Protein binding of isofluorophate in vivo after coexposure to multiple chemicals. | Environmental health perspectives 20021201 |
| Myasthenia mimicking vertebrobasilar stroke. | Journal of neurology 20021101 |
| In myasthenia gravis, clinical and immunological improvement post-thymectomy segregate with results of in vitro antibody secretion by immunocytes. | Journal of the neurological sciences 20021015 |
| Pharmacokinetic/pharmacodynamic modeling of rocuronium in myasthenic patients is improved by taking into account the number of unbound acetylcholine receptors. | Anesthesia and analgesia 20020901 |
| Complete inhibition of hypothalamic somatostatin activity is only partially responsible for the growth hormone response to strenuous exercise. | Metabolism: clinical and experimental 20020901 |
| Acute and repeated restraint stress have little effect on pyridostigmine toxicity or brain regional cholinesterase inhibition in rats. | Toxicological sciences : an official journal of the Society of Toxicology 20020901 |
| Physostigmine and hyoscine improves protection against the lethal and incapacitating effects of nerve agent poisoning in the guinea-pig. | Neurotoxicology 20020901 |
| Preparation and in vitro evaluation of pyridostigmine bromide microparticles. | International journal of pharmaceutics 20020821 |
| A comparison of the efficacy of pyridostigmine alone and the combination of pyridostigmine with anticholinergic drugs as pharmacological pretreatment of tabun-poisoned rats and mice. | Toxicology 20020815 |
| Myasthenia gravis in pregnancy: report on 69 cases. | European journal of obstetrics, gynecology, and reproductive biology 20020805 |
| Locomotor and sensorimotor performance deficit in rats following exposure to pyridostigmine bromide, DEET, and permethrin. Alone and in combination. | Toxicological sciences : an official journal of the Society of Toxicology 20020801 |
| Subchronic administration of pyridostigmine or huperzine to primates: compared efficacy against soman toxicity. | Drug and chemical toxicology 20020801 |
| Altered hypothalamic cholinergic responses in patients with nonulcer dyspepsia: a study of pyridostigmine-stimulated growth hormone release. | The American journal of gastroenterology 20020801 |
| Neither forced running nor forced swimming affect acute pyridostigmine toxicity or brain-regional cholinesterase inhibition in rats. | Toxicology 20020701 |
| Sensitivity to vecuronium in seropositive and seronegative patients with myasthenia gravis. | Anesthesia and analgesia 20020701 |
| Physiological and performance effects of pyridostigmine bromide in healthy volunteers: a dose-response study. | Psychopharmacology 20020701 |
| Use of intravenous pulsed cyclophosphamide in severe, generalized myasthenia gravis. | Muscle & nerve 20020701 |
| [Ptosis and mastication disorders revealing concurrent myasthenia gravis and chronic polyradiculoneuritis]. | Revue neurologique 20020701 |
| Pyridostigmine bromide modulates the dermal disposition of [14C]permethrin. | Toxicology and applied pharmacology 20020615 |
| [Growth disorders in Down's syndrome: growth hormone treatment]. | Minerva endocrinologica 20020601 |
| Cholinergic stimulation with pyridostigmine reduces the QTc interval in coronary artery disease. | Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas 20020601 |
| Pyridostigmine bromide and the long-term subjective health status of a sample of over 700 male Reserve Component Gulf War era veterans. | Psychological reports 20020601 |
| Actions of pyridostigmine and organophosphate agents on chick cells, mice, and chickens. | Drug and chemical toxicology 20020501 |
| Binding of pyridostigmine bromide, N,N-diethyl-m-toluamide and permethrin, alone and in combinations, to human serum albumin. | Archives of toxicology 20020501 |
| Impaired growth hormone secretion in fibromyalgia patients: evidence for augmented hypothalamic somatostatin tone. | Arthritis and rheumatism 20020501 |
| In vitro human metabolism and interactions of repellent N,N-diethyl-m-toluamide. | Drug metabolism and disposition: the biological fate of chemicals 20020301 |
| Sensorimotor deficit and cholinergic changes following coexposure with pyridostigmine bromide and sarin in rats. | Toxicological sciences : an official journal of the Society of Toxicology 20020301 |
| Indirect evidence for decreased hypothalamic somatostatinergic tone in anorexia nervosa. | Clinical endocrinology 20020301 |
| Pyridophens: binary pyridostigmine-aprophen prodrugs with differential inhibition of acetylcholinesterase, butyrylcholinesterase, and muscarinic receptors. | Journal of medicinal chemistry 20020214 |
| Peripheral cholinergic pathway modulates hyperthermia induced by stress in rats exposed to open-field stress. | Journal of applied physiology (Bethesda, Md. : 1985) 20020201 |
| Presentation of myasthenia gravis mimicking blepharospasm. | Neurology 20020108 |
| Prevention and treatment of injury from chemical warfare agents. | The Medical letter on drugs and therapeutics 20020107 |
| The use of the pyridostigmine growth hormone-releasing hormone stimulation test to detect growth hormone deficiency in patients with pituitary adenomas. | Metabolism: clinical and experimental 20020101 |
| Ocular myasthenia presenting as progressive external ophthalmoplegia. | Journal of pediatric ophthalmology and strabismus 20020101 |
| Major review: the clinical spectrum of pediatric myasthenia gravis: blepharoptosis, ophthalmoplegia and strabismus. A report of 14 cases. | Binocular vision & strabismus quarterly 20020101 |
| Cardiorespiratory effects following acute exposure to pyridostigmine bromide and/or N,N-diethyl-m-toluamide (DEET) in rats. | International journal of toxicology 20020101 |
| [Respiratory arrests caused by congenital myasthenia gravis syndrome]. | Duodecim; laaketieteellinen aikakauskirja 20020101 |
| Determination of physostigmine and pyridostigmine in pharmaceutical formulations by capillary electrophoresis. | Journal of capillary electrophoresis and microchip technology 20020101 |
| A validated HPLC method for the determination of pyridostigmine bromide, acetaminophen, acetylsalicylic acid and caffeine in rat plasma and urine. | Journal of pharmaceutical and biomedical analysis 20011201 |
| Effects of contralateral white noise stimulation on distortion product otoacoustic emissions in myasthenic patients. | Hearing research 20011201 |
| Side effects of low-dose pyridostigmine bromide are not related to cholinesterase inhibition. | Aviation, space, and environmental medicine 20011201 |
| The effect of continuous pyridostigmine administration on functional (A12) acetylcholinesterase activity in guinea-pig muscles. | Neurotoxicology 20011201 |
| Insulin-like growth factor-I restores the reduced somatostatinergic tone controlling growth hormone secretion in cirrhotic rats. | Liver 20011201 |
| Beneficial effects of TCP on soman intoxication in guinea pigs: seizures, brain damage and learning behaviour. | Journal of applied toxicology : JAT 20011201 |
| Reactive oxygen species mediate pyridostigmine-induced neuronal apoptosis: involvement of muscarinic and NMDA receptors. | Toxicology and applied pharmacology 20011115 |
| Fetal antigen 1 in healthy adults and patients with pituitary disease: relation to physiological, pathological, and pharmacological GH levels. | The Journal of clinical endocrinology and metabolism 20011101 |
| Determination of depleted uranium, pyridostigmine bromide and its metabolite in plasma and urine following combined administration in rats. | Journal of pharmaceutical and biomedical analysis 20010901 |
| The use of carbamates, atropine, and 2-pyridine aldoxime methoiodide in the protection of Artemia salina against poisoning by carbophenothion. | Environmental toxicology and chemistry 20010901 |
| Electroplegia: an alternative to blood cardioplegia for arresting the heart during conventional (on-pump) cardiac operation. | The Annals of thoracic surgery 20010901 |
| Myasthenia gravis in children: analysis of 18 patients. | Arquivos de neuro-psiquiatria 20010901 |
| Combined exposure to sarin and pyridostigmine bromide increased levels of rat urinary 3-nitrotyrosine and 8-hydroxy-2'-deoxyguanosine, biomarkers of oxidative stress. | Toxicology letters 20010806 |
| High-performance liquid chromatographic determination of pyridostigmine bromide, nicotine, and their metabolites in rat plasma and urine. | Journal of chromatographic science 20010701 |
| Pyridostigmine-induced microcephaly. | Neurology 20010612 |
| Pyridostigmine-induced microcephaly. | Neurology 20010612 |
| Evaluation of immunotoxicity induced by single or concurrent exposure to N,N-diethyl-m-toluamide (DEET), pyridostigmine bromide (PYR), and JP-8 jet fuel. | Toxicology and industrial health 20010601 |
| Myasthenia gravis with autoimmune autonomic neuropathy. | Autonomic neuroscience : basic & clinical 20010514 |
| Subchronic administration of various pretreatments of nerve agent poisoning. I. Protection of blood and central cholinesterases, innocuousness towards blood-brain barrier permeability. | Drug and chemical toxicology 20010501 |
| Subchronic administration of various pretreatments of nerve agent poisoning. II. Compared efficacy against soman toxicity. | Drug and chemical toxicology 20010501 |
| Impairment of GH responsiveness to GH-releasing hexapeptide (GHRP-6) in Prader-Willi syndrome. | Journal of endocrinological investigation 20010501 |
| Induction of urinary excretion of 3-nitrotyrosine, a marker of oxidative stress, following administration of pyridostigmine bromide, DEET (N,N-diethyl-m-toluamide) and permethrin, alone and in combination in rats. | Toxicology letters 20010430 |
| Chromatographic method for the determination of diazepam, pyridostigmine bromide, and their metabolites in rat plasma and urine. | Journal of chromatography. B, Biomedical sciences and applications 20010425 |
| Development of a high-performance liquid chromatographic method for the quantification of chlorpyrifos, pyridostigmine bromide, N,N-diethyl-m-toluamide and their metabolites in rat plasma and urine. | Journal of chromatography. B, Biomedical sciences and applications 20010425 |
| Locomotor and sensorimotor performance deficit in rats following exposure to pyridostigmine bromide, DEET, and permethrin, alone and in combination. | Toxicological sciences : an official journal of the Society of Toxicology 20010401 |
| Analysis of thymectomy for myasthenia gravis in older patients: a 20-year single institution experience. | Journal of the American College of Surgeons 20010401 |
| Exercise stress testing in healthy subjects during cholinergic stimulation after a single dose of pyridostigmine. | Arquivos brasileiros de cardiologia 20010401 |
| Familial autoimmune myasthenia gravis. | Singapore medical journal 20010401 |
| Cocaine abuse, generalized myasthenia, complete external ophthalmoplegia, and pseudotonic pupil. | Strabismus 20010301 |
| Central nervous system effects from a peripherally acting cholinesterase inhibiting agent: interaction with stress or genetics. | Annals of the New York Academy of Sciences 20010301 |
| Laryngeal myasthenia gravis: report of 40 cases. | Journal of voice : official journal of the Voice Foundation 20010301 |
| Pyridostigmine bromide and the long-term subjective health status of a sample of female reserve component Gulf War veterans: a brief report. | Psychological reports 20010201 |
| Perioperative management of a patient with congenital myasthenia gravis for elective caesarean section. | Singapore medical journal 20010201 |
| Many Gulf War illnesses may be autoimmune disorders caused by the chemical and biological stressors pyridostigmine bromide, and adrenaline. | Medical hypotheses 20010201 |
| Enhancement of heart rate variability by cholinergic stimulation with pyridostigmine in healthy subjects. | Clinical autonomic research : official journal of the Clinical Autonomic Research Society 20010201 |
| Viral neuroinvasion as a marker for BBB integrity following exposure to cholinesterase inhibitors. | Life sciences 20010119 |
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