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CAS No: 10097-84-4 Catalog No: AG00IKHZ MDL No:MFCD00214191
Title | Journal |
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Effects of tetrahydroberberine and tetrahydropalmatine on hepatic cytochrome P450 expression and their toxicity in mice. | Chemico-biological interactions 20170425 |
Application of an in vitro DDASS to evaluate oral absorption of two chemicals simultaneously: establishment of a level A in vitro-in vivo correlation. | Drug development and industrial pharmacy 20121101 |
Design and evaluation of self-emulsifying drug delivery systems of Rhizoma corydalis decumbentis extracts. | Drug development and industrial pharmacy 20121001 |
Differential effect of isoflurane, medetomidine, and urethane on BOLD responses to acute levo-tetrahydropalmatine in the rat. | Magnetic resonance in medicine 20120801 |
The dopamine receptor antagonist levo-tetrahydropalmatine attenuates heroin self-administration and heroin-induced reinstatement in rats. | Pharmacology, biochemistry, and behavior 20120701 |
Comprehensive two-dimensional HepG2/cell membrane chromatography/monolithic column/time-of-flight mass spectrometry system for screening anti-tumor components from herbal medicines. | Journal of chromatography. A 20120615 |
Tetrahydropalmatine protects against methamphetamine-induced spatial learning and memory impairment in mice. | Neuroscience bulletin 20120601 |
Rapid determination and comparative pharmacokinetics of tetrahydropalmatine in spontaneously hypertensive rats and normotensive rats. | Biomedical chromatography : BMC 20120601 |
Microdialysis combined with liquid chromatography-tandem mass spectrometry for the determination of levo-tetrahydropalmatine in the rat striatum. | Journal of pharmaceutical and biomedical analysis 20120501 |
Stereoselective metabolism of tetrahydropalmatine enantiomers in rat liver microsomes. | Chirality 20120501 |
Analysis of herbal dietary supplements for sexual performance enhancement: first characterization of propoxyphenyl-thiohydroxyhomosildenafil and identification of sildenafil, thiosildenafil, phentolamine and tetrahydropalmatine as adulterants. | Journal of pharmaceutical and biomedical analysis 20120407 |
[Tetrahydropalmatine's permeative properties of acupoint and non-acupoint transdermal administration of Baijiezi Tufang in vitro and in vivo]. | Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20120401 |
Rapid discrimination and quantification of alkaloids in Corydalis Tuber by near-infrared spectroscopy. | Journal of pharmaceutical and biomedical analysis 20120205 |
The in vitro inhibition of human CYP1A2, CYP2D6 and CYP3A4 by tetrahydropalmatine, neferine and berberine. | Phytotherapy research : PTR 20120201 |
Responses of dopaminergic, serotonergic and noradrenergic networks to acute levo-tetrahydropalmatine administration in naïve rats detected at 9.4 T. | Magnetic resonance imaging 20120201 |
l-tetrahydropalamatine: a potential new medication for the treatment of cocaine addiction. | Future medicinal chemistry 20120201 |
Effect of wine and vinegar processing of Rhizoma Corydalis on the tissue distribution of tetrahydropalmatine, protopine and dehydrocorydaline in rats. | Molecules (Basel, Switzerland) 20120118 |
l-Tetrahydropalmatine, an active component of Corydalis yanhusuo W.T. Wang, protects against myocardial ischaemia-reperfusion injury in rats. | PloS one 20120101 |
[Chemical constituents from Corydalis yanhusuo]. | Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20120101 |
Determination of L-tetrahydropalmatine in human plasma by HPLC and pharmacokinetics of its disintegrating tablets in healthy Chinese. | European journal of drug metabolism and pharmacokinetics 20111201 |
Antinociceptive effects of intragastric DL-tetrahydropalmatine on visceral and somatic persistent nociception and pain hypersensitivity in rats. | Pharmacology, biochemistry, and behavior 20111101 |
Simultaneous determination of tetrahydropalmatine and tetrahydroberberine in rat urine using dispersive liquid-liquid microextraction coupled with high-performance liquid chromatography. | Journal of separation science 20111101 |
[Effect of salvianolic acid B and tetrahydropalmatine on the L-type calcium channel of rat ventricular myocytes]. | Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine 20111101 |
The retardation of myometrial infiltration, reduction of uterine contractility, and alleviation of generalized hyperalgesia in mice with induced adenomyosis by levo-tetrahydropalmatine (l-THP) and andrographolide. | Reproductive sciences (Thousand Oaks, Calif.) 20111001 |
Correlation between rheological properties, in vitro release, and percutaneous permeation of tetrahydropalmatine. | AAPS PharmSciTech 20110901 |
[Study on method of Corydalis yanhusuo producing and concocting integration processing]. | Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20110901 |
Oral administration of levo-tetrahydropalmatine attenuates reinstatement of extinguished cocaine seeking by cocaine, stress or drug-associated cues in rats. | Drug and alcohol dependence 20110701 |
[Study on the initial processing of Corydalis yanhusuo]. | Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials 20110701 |
[Enhancing effect of volatile oils of rhizoma zingiberis, flos magnoliae and fructus litseae on permeation of rotundine in vitro]. | Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials 20110501 |
[Simultaneous determination of four alkaloids in Corydalis decumbens (Thunb.) Pers. by high performance liquid chromatography-tandem mass spectrometry]. | Se pu = Chinese journal of chromatography 20110201 |
Levo-tetrahydropalmatine retards the growth of ectopic endometrial implants and alleviates generalized hyperalgesia in experimentally induced endometriosis in rats. | Reproductive sciences (Thousand Oaks, Calif.) 20110101 |
[Inhibitory and inductive effects of (-)- and (+)-tetrahydropalmatine on CYP450 in mice]. | Zhejiang da xue xue bao. Yi xue ban = Journal of Zhejiang University. Medical sciences 20110101 |
Novel pharmacotherapeutic treatments for cocaine addiction. | BMC medicine 20110101 |
Levo-tetrahydropalmatine attenuates cocaine self-administration under a progressive-ratio schedule and cocaine discrimination in rats. | Pharmacology, biochemistry, and behavior 20101201 |
Tetrahydropalmatine inhibits pro-inflammatory mediators in lipopolysaccharide-stimulated THP-1 cells. | Journal of medicinal food 20101001 |
Protective effects of tetrahydropalmatine against gamma-radiation induced damage to human endothelial cells. | Life sciences 20100703 |
Combined comparative and chemical proteomics on the mechanisms of levo-tetrahydropalmatine-induced antinociception in the formalin test. | Journal of proteome research 20100604 |
Stereoselective protein binding of tetrahydropalmatine enantiomers in human plasma, HSA, and AGP, but not in rat plasma. | Chirality 20100601 |
Affinity capillary electrophoresis coupling with partial filling technique and field-amplified sample injection for enantioseparation and determination of DL-tetrahydropalmatine. | Electrophoresis 20100601 |
Simultaneous HPLC determination of three bioactive alkaloids in the Asian medicinal plant Stephania rotunda. | Natural product communications 20100601 |
Correlation between synergistic action of Radix Angelica dahurica extracts on analgesic effects of Corydalis alkaloid and plasma concentration of dl-THP. | Journal of ethnopharmacology 20100504 |
Shotgun approach based comparative proteomic analysis of levo-tetrahydropalmatine-induced apoptosis in hepatocytes. | Toxicology letters 20100415 |
Study on the stereoselective excretion of tetrahydropalmatine enantiomers in rats and identification of in vivo metabolites by liquid chromatography-tandem mass spectrometry. | Chirality 20100301 |
[In vitro O-demethylation of rotundine by recombinant human CYP isoenzymes]. | Yao xue xue bao = Acta pharmaceutica Sinica 20100301 |
[Comparison of pharmacokinetics about ermiao capsules and ermiao pellet]. | Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials 20100201 |
[Effects of four components of Rhizoma Corydalis on anoxia and peroxidation injuries in neonatal cardiomyocytes]. | Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20100101 |
[Study on the influence on Rhizoma Corydalis by different harvest time and processing methods]. | Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials 20090701 |
[Comparison of microwave-assisted and conventional extraction of Corydalis yanhusuo]. | Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials 20090701 |
[Influence of combination of extractum Angelicae Dahuricae Siccum and total alkaloids of Rhizoma Corydalis on pharmacokinetics of tetrahydropalmatine in rats]. | Yao xue xue bao = Acta pharmaceutica Sinica 20090601 |
Purification of alkaloids from Corydalis yanhusuo W. T. Wang using preparative 2-D HPLC. | Journal of separation science 20090501 |
[Pharmacokinetics of three alkaloids in Huanglianjiedu decoction in rat serum by LC-MS-MS]. | Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20090501 |
Phytochemicals from Flemingia vestita (Fabaceae) and Stephania glabra (Menispermeaceae) alter cGMP concentration in the cestode Raillietina echinobothrida. | Comparative biochemistry and physiology. Toxicology & pharmacology : CBP 20090401 |
Cytotoxic activity of alkaloids isolated from Stephania rotunda [corrected]. | Phytotherapy research : PTR 20090401 |
Simultaneous determination of tetrahydropalmatine, protopine, and palmatine in rat plasma by LC-ESI-MS and its application to a pharmacokinetic study. | Journal of pharmaceutical and biomedical analysis 20090220 |
Levo-tetrahydropalmatine attenuates oxycodone-induced conditioned place preference in rats. | European journal of pharmacology 20090114 |
Amphiphilic poly{[alpha-maleic anhydride-omega-methoxy-poly(ethylene glycol)]-co-(ethyl cyanoacrylate)} graft copolymer nanoparticles as carriers for transdermal drug delivery. | International journal of nanomedicine 20090101 |
Investigation of modulation of the alpha-2 receptor in tetrahydropalmatine (THP) analgesia in male Sprague-Dawley rats. | Journal of dietary supplements 20090101 |
[Pharmacokinetic studies of tetrahydropalmatine and dehydrocorydaline in rat after oral administration of yanhusuo extraction by LC-MS/MS method]. | Yao xue xue bao = Acta pharmaceutica Sinica 20081101 |
One-step purification of palmatine and its derivative dl-tetrahydropalmatine from Enantia chlorantha using high-performance displacement chromatography. | Journal of chromatography. A 20081024 |
Isoquinoline alkaloids isolated from Corydalis yanhusuo and their binding affinities at the dopamine D1 receptor. | Molecules (Basel, Switzerland) 20080925 |
Medication of l-tetrahydropalmatine significantly ameliorates opiate craving and increases the abstinence rate in heroin users: a pilot study. | Acta pharmacologica Sinica 20080701 |
[Studies on active ingredients in Corydalis, broken cell wall corydalis and its processed products]. | Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20080601 |
Simultaneous determination of berberine, palmatine and jatrorrhizine by liquid chromatography-tandem mass spectrometry in rat plasma and its application in a pharmacokinetic study after oral administration of coptis-evodia herb couple. | Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20080301 |
Comparative studies on pharmacokinetic fates of tetrahydropalmatine enantiomers in different chemical environments in rats. | Chirality 20080201 |
[Comparison of pharmacokinetics of tetrahydropalmatine monomer and extractive of corydalis and corydalis processed with vinegar]. | Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials 20071201 |
Levo-tetrahydropalmatine inhibits cocaine's rewarding effects: experiments with self-administration and brain-stimulation reward in rats. | Neuropharmacology 20071101 |
[Optimal extraction of Dingxiang jiangqi granules]. | Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20071101 |
Levo-tetrahydropalmatine attenuates cocaine self-administration and cocaine-induced reinstatement in rats. | Psychopharmacology 20070701 |
[Effects of rotundine injection on nitric oxide synthase in tissues of different organs after ischemia/reperfusion of brain in rats]. | Zhongguo wei zhong bing ji jiu yi xue = Chinese critical care medicine = Zhongguo weizhongbing jijiuyixue 20070601 |
[Difference absorption of l-tetrahydropalmatine and dl-tetrahydropalmatine in intestine of rats]. | Yao xue xue bao = Acta pharmaceutica Sinica 20070501 |
Enantioseparation of tetrahydropalmatine and Tröger's base by molecularly imprinted monolith in capillary electrochromatography. | Journal of biochemical and biophysical methods 20070223 |
Characterization of enantioselective binding of racemic natural tetrahydropalmatine to DNA by chromatographic methods. | Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20070101 |
Determination of DL-tetrahydropalmatine in Corydalis yanhusuo by L-tetrahydropalmatine imprinted monolithic column coupling with reversed-phase high performance liquid chromatography. | Journal of chromatography. A 20060609 |
Large-scale separation of alkaloids from Corydalis decumbens by pH-zone-refining counter-current chromatography. | Journal of chromatography. A 20060519 |
Brain pharmacokinetics and tissue distribution of tetrahydropalmatine enantiomers in rats after oral administration of the racemate. | Biopharmaceutics & drug disposition 20060401 |
[Effects of different types and standard of processing vinegaron inherent constituents in rhizoma of Corydalis yanhusuo]. | Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20060301 |
[Protective effect of dl-tetrahydropalmatine on liver injury induced by carbon tetrachloride in mice]. | Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20060301 |
Chiral high-performance liquid chromatographic separation of the enantiomers of tetrahydropalmatine and tetrahydroberberine, isolated from Corydalis yanhusuo. | Analytical and bioanalytical chemistry 20060201 |
Anxiolytic-Like Effect of baicalin and its additivity with other anxiolytics. | Planta medica 20060201 |
Liquid chromatography-tandem mass spectrometry for the identification of L-tetrahydropalmatine metabolites in Penicillium janthinellum and rats. | Biomedical chromatography : BMC 20060101 |
Asymmetric synthesis of tetrahydropalmatine via tandem 1,2-addition/cyclization. | The Journal of organic chemistry 20051111 |
Chiral liquid chromatography resolution and stereoselective pharmacokinetic study of tetrahydropalmatine enantiomers in dogs. | Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20051105 |
[Studies on the alkaloids from herb of Corydalis adunca]. | Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20051101 |
[Stereoselective pharmacokinetics of tetrahydropalmatine in rats]. | Yao xue xue bao = Acta pharmaceutica Sinica 20050801 |
Discovery of high-affinity ligands of sigma1 receptor, ERG2, and emopamil binding protein by pharmacophore modeling and virtual screening. | Journal of medicinal chemistry 20050728 |
[Chemical constituents from Corydalis humosa]. | Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials 20050701 |
[Effect of l-tetrahydropalmatine on expression of adhesion molecules induced by lipopolysaccharides in human umbilical vein endothelium cell]. | Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20050601 |
Stereoselective pharmacokinetics of tetrahydropalmatine after oral administration of (-)-enantiomer and the racemate. | Chirality 20050515 |
Effects of l-tetrahydropalmatine on locomotor sensitization to oxycodone in mice. | Acta pharmacologica Sinica 20050501 |
[Resource investigation and quality evaluation on wild Corydalis yanhusuo]. | Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20040501 |
[Effects of L-tetrahydropalmatine on concentrations of neurotransmitter amino acids in mice with cerebral ischemia]. | Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20040401 |
Effects of L-tetrahydropalmatine on the expressions of bcl-2 and bax in rat after acute global cerebral ischemia and reperfusion. | Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban 20040101 |
[Study on extraction conditions for minute powder of processed rhizome of Corydalis with vinegar]. | Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20031001 |
Anxiolytic-like action of orally administered dl-tetrahydropalmatine in elevated plus-maze. | Progress in neuro-psychopharmacology & biological psychiatry 20030801 |
The protective effect of dl-tetrahydropalmatine against the development of amygdala kindling seizures in rats. | Neuroscience letters 20020308 |
Formation of protoberberine-type alkaloids by the tubers of somatic embryo-derived plants of Corydalis yanhusuo. | Planta medica 20011201 |
The hypothermic effects of dl-tetrahydropalmatine in rats. | Neuroscience letters 20011123 |
Influence of light and heat on the stability of rotundine sulfate injection. | Journal of pharmaceutical sciences 20011001 |
DL-Tetrahydropalmatine may act through inhibition of amygdaloid release of dopamine to inhibit an epileptic attack in rats. | Neuroscience letters 20010720 |
DL-tetrahydropalmatine-produced hypotension and bradycardia in rats through the inhibition of central nervous dopaminergic mechanisms. | Pharmacology 19951001 |
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