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CAS No: 100929-53-1 Catalog No: AG00038D MDL No:
Title | Journal |
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Functional and structural characterization of axonal opioid receptors as targets for analgesia. | Molecular pain 20160101 |
Role of G Protein-Coupled Receptor Kinases 2 and 3 in μ-Opioid Receptor Desensitization and Internalization. | Molecular pharmacology 20150801 |
μ-Opioid Receptor-Mediated Inhibition of Intercalated Neurons and Effect on Synaptic Transmission to the Central Amygdala. | The Journal of neuroscience : the official journal of the Society for Neuroscience 20150513 |
The novel mu-opioid antagonist, GSK1521498, reduces ethanol consumption in C57BL/6J mice. | Psychopharmacology 20150101 |
μ-Opioid inhibition of Ca2+ currents and secretion in isolated terminals of the neurohypophysis occurs via ryanodine-sensitive Ca2+ stores. | The Journal of neuroscience : the official journal of the Society for Neuroscience 20140305 |
Powerful inhibitory action of mu opioid receptors (MOR) on cholinergic interneuron excitability in the dorsal striatum. | Neuropharmacology 20131201 |
Accumbal core: essential link in feed-forward spiraling striato-nigro-striatal in series connected loop. | Neuroscience 20131112 |
Deciphering µ-opioid receptor phosphorylation and dephosphorylation in HEK293 cells. | British journal of pharmacology 20121101 |
Pontine μ-opioid receptors mediate bradypnea caused by intravenous remifentanil infusions at clinically relevant concentrations in dogs. | Journal of neurophysiology 20121101 |
Direct regulation of GnRH neuron excitability by arcuate nucleus POMC and NPY neuron neuropeptides in female mice. | Endocrinology 20121101 |
Pain-facilitating medullary neurons contribute to opioid-induced respiratory depression. | Journal of neurophysiology 20121101 |
Enkephalin surges in dorsal neostriatum as a signal to eat. | Current biology : CB 20121023 |
The mu opioid receptor modulates neurotransmission in the rat spinal ventral horn. | Anesthesia and analgesia 20120901 |
Disturbances in behavior and cortical enkephalin gene expression during the anticipation of ethanol in rats characterized as high drinkers. | Alcohol (Fayetteville, N.Y.) 20120901 |
Effects of peripheral μ, δ, and Κ-opioid receptor agonists on the levels of anxiety and motor activity of rats. | Bulletin of experimental biology and medicine 20120901 |
A118G Mu Opioid Receptor polymorphism increases inhibitory effects on CaV2.2 channels. | Neuroscience letters 20120815 |
Endomorphin-2: a biased agonist at the μ-opioid receptor. | Molecular pharmacology 20120801 |
Inhibition of forebrain μ-opioid receptor signaling by low concentrations of rimonabant does not require cannabinoid receptors and directly involves μ-opioid receptors. | Neurochemistry international 20120801 |
Selective impairment of spinal mu-opioid receptor mechanism by plasticity of serotonergic facilitation mediated by 5-HT2A and 5-HT2B receptors. | Pain 20120701 |
Quantitative analysis of the opioid peptide DAMGO in rat plasma and microdialysis samples using liquid chromatography-tandem mass spectrometry. | Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20120701 |
Differences in the characteristics of tolerance to μ-opioid receptor agonists in the colon from wild type and β-arrestin2 knockout mice. | European journal of pharmacology 20120615 |
What and when to 'want'? Amygdala-based focusing of incentive salience upon sugar and sex. | Psychopharmacology 20120601 |
Modulation of tight junction proteins in the perineurium to facilitate peripheral opioid analgesia. | Anesthesiology 20120601 |
Genetic differences in response properties of rostral ventromedial medulla neurons to the μ-opioid receptor agonist DAMGO in mouse inbred strains. | Neuroscience letters 20120531 |
Effects of muscimol, amphetamine, and DAMGO injected into the nucleus accumbens shell on food-reinforced lever pressing by undeprived rats. | Pharmacology, biochemistry, and behavior 20120501 |
An examination of the effects of subthalamic nucleus inhibition or μ-opioid receptor stimulation on food-directed motivation in the non-deprived rat. | Behavioural brain research 20120501 |
Which cue to 'want'? Opioid stimulation of central amygdala makes goal-trackers show stronger goal-tracking, just as sign-trackers show stronger sign-tracking. | Behavioural brain research 20120501 |
Fast modulation of μ-opioid receptor (MOR) recycling is mediated by receptor agonists. | The Journal of biological chemistry 20120427 |
GRK2 protein-mediated transphosphorylation contributes to loss of function of μ-opioid receptors induced by neuropeptide FF (NPFF2) receptors. | The Journal of biological chemistry 20120413 |
Regulatory mechanism of body temperature in the central nervous system during the maintenance phase of hibernation in Syrian hamsters: involvement of β-endorphin. | Brain research 20120411 |
A critical period in the supraspinal control of pain: opioid-dependent changes in brainstem rostroventral medulla function in preadolescence. | Pain 20120401 |
Opioid-related (ORL1) receptors are enriched in a subpopulation of sensory neurons and prolonged activation produces no functional loss of surface N-type calcium channels. | The Journal of physiology 20120401 |
Ethanol alters opioid regulation of Ca(2+) influx through L-type Ca(2+) channels in PC12 cells. | Alcoholism, clinical and experimental research 20120301 |
[(35)S]GTPγS binding and opioid tolerance and efficacy in mouse spinal cord. | Pharmacology, biochemistry, and behavior 20120301 |
Activation of mu opioid receptors in the striatum differentially augments methamphetamine-induced gene expression and enhances stereotypic behavior. | Journal of neurochemistry 20120301 |
Protein kinase C activity alters the effect of μ-opioid receptors on inhibitory postsynaptic current in the striosomes. | Neuroreport 20120215 |
The central versus peripheral antinociceptive effects of μ-opioid receptor agonists in the new model of rat visceral pain. | Brain research bulletin 20120210 |
Opioidergic modulation of ethanol self-administration in the ventral pallidum. | Alcoholism, clinical and experimental research 20120201 |
Tonic GABAA receptor conductance in medial subnucleus of the tractus solitarius neurons is inhibited by activation of μ-opioid receptors. | Journal of neurophysiology 20120201 |
Opiate agonist-induced re-distribution of Wntless, a mu-opioid receptor interacting protein, in rat striatal neurons. | Experimental neurology 20120101 |
Regional and cell-type-specific effects of DAMGO on striatal D1 and D2 dopamine receptor-expressing medium-sized spiny neurons. | ASN neuro 20120101 |
Importance of GluA1 subunit-containing AMPA glutamate receptors for morphine state-dependency. | PloS one 20120101 |
[Effect of opioid peptides on oxygen-dependent microbicidity of peripheral blood neutrophils]. | Fiziologiia cheloveka 20120101 |
A novel µ-opioid receptor ligand with high in vitro and in vivo agonist efficacy. | Current medicinal chemistry 20120101 |
Involvement of NOX1/NADPH oxidase in morphine-induced analgesia and tolerance. | The Journal of neuroscience : the official journal of the Society for Neuroscience 20111207 |
Role of gonadal hormones on mu-opioid-stimulated [³⁵S]GTPγS binding and morphine-mediated antinociception in male and female Sprague-Dawley rats. | Psychopharmacology 20111201 |
Effect of ΔFosB overexpression on opioid and cannabinoid receptor-mediated signaling in the nucleus accumbens. | Neuropharmacology 20111201 |
Opioid-sensitive GABA inputs from rostromedial tegmental nucleus synapse onto midbrain dopamine neurons. | The Journal of neuroscience : the official journal of the Society for Neuroscience 20111130 |
Ivy and neurogliaform interneurons are a major target of μ-opioid receptor modulation. | The Journal of neuroscience : the official journal of the Society for Neuroscience 20111019 |
Neuroadaptation of GABAergic transmission in the central amygdala during chronic morphine treatment. | Addiction biology 20111001 |
Activation of spinal mu- and delta-opioid receptors potently inhibits substance P release induced by peripheral noxious stimuli. | The Journal of neuroscience : the official journal of the Society for Neuroscience 20110914 |
Agonist-directed interactions with specific beta-arrestins determine mu-opioid receptor trafficking, ubiquitination, and dephosphorylation. | The Journal of biological chemistry 20110909 |
Agonist-selective patterns of µ-opioid receptor phosphorylation revealed by phosphosite-specific antibodies. | British journal of pharmacology 20110901 |
μ-Opioid modulation in the rostral solitary nucleus and reticular formation alters taste reactivity: evidence for a suppressive effect on consummatory behavior. | American journal of physiology. Regulatory, integrative and comparative physiology 20110901 |
RGS9-2 modulates nociceptive behaviour and opioid-mediated synaptic transmission in the spinal dorsal horn. | Neuroscience letters 20110821 |
Chronic neuropathic pain in mice reduces μ-opioid receptor-mediated G-protein activity in the thalamus. | Brain research 20110811 |
Dynamic mass redistribution as a means to measure and differentiate signaling via opioid and cannabinoid receptors. | Assay and drug development technologies 20110801 |
Distinct cellular properties of identified dopaminergic and GABAergic neurons in the mouse ventral tegmental area. | The Journal of physiology 20110801 |
Activation of opioid μ-receptors in the commissural subdivision of the nucleus tractus solitarius abolishes the ventilatory response to hypoxia in anesthetized rats. | Anesthesiology 20110801 |
A μ-opioid receptor agonist DAMGO induces rapid breathing in the arterially perfused in situ preparation of rat. | Respiratory physiology & neurobiology 20110731 |
mu-Opioid receptor stimulation in the nucleus accumbens elevates fatty tastant intake by increasing palatability and suppressing satiety signals. | American journal of physiology. Regulatory, integrative and comparative physiology 20110701 |
Protein kinase Czeta mediates micro-opioid receptor-induced cross-desensitization of chemokine receptor CCR5. | The Journal of biological chemistry 20110610 |
Nucleus accumbens dopamine and mu-opioid receptors modulate the reinstatement of food-seeking behavior by food-associated cues. | Behavioural brain research 20110601 |
Nucleus accumbens facilitates nociception. | Experimental neurology 20110601 |
Spinal motor actions of the μ-opioid receptor agonist DAMGO in the cat. | Neuroscience research 20110501 |
Modulating micro-opioid receptor phosphorylation switches agonist-dependent signaling as reflected in PKCepsilon activation and dendritic spine stability. | The Journal of biological chemistry 20110408 |
Opioid-induced down-regulation of RGS4: role of ubiquitination and implications for receptor cross-talk. | The Journal of biological chemistry 20110311 |
Induction of hyperphagia and carbohydrate intake by μ-opioid receptor stimulation in circumscribed regions of frontal cortex. | The Journal of neuroscience : the official journal of the Society for Neuroscience 20110302 |
Gi/o-coupled receptors compete for signaling to adenylyl cyclase in SH-SY5Y cells and reduce opioid-mediated cAMP overshoot. | Molecular pharmacology 20110301 |
Differentiation between Aδ and C fibre evoked nociceptive reflexes by TTX resistance and opioid sensitivity in the cat. | Neuroscience research 20110301 |
Involvement of the lateral amygdala in the antiallodynic and reinforcing effects of heroin in rats after peripheral nerve injury. | Anesthesiology 20110301 |
Micro-opioid receptor activation in the basolateral amygdala mediates the learning of increases but not decreases in the incentive value of a food reward. | The Journal of neuroscience : the official journal of the Society for Neuroscience 20110202 |
Opioid-induced chemokine expression requires NF-κB activity: the role of PKCζ. | Journal of leukocyte biology 20110201 |
Morphine induces μ opioid receptor endocytosis in guinea pig enteric neurons following prolonged receptor activation. | Gastroenterology 20110201 |
Multiple targets of μ-opioid receptor-mediated presynaptic inhibition at primary afferent Aδ- and C-fibers. | The Journal of neuroscience : the official journal of the Society for Neuroscience 20110126 |
Involvement of mouse μ-opioid receptor splice variants in the spinal antinociception induced by the dermorphin tetrapeptide analog amidino-TAPA. | European journal of pharmacology 20110125 |
μ-Opioid receptors in the nucleus accumbens shell region mediate the effects of amphetamine on inhibitory control but not impulsive choice. | The Journal of neuroscience : the official journal of the Society for Neuroscience 20110105 |
Differential expression and sensitivity of presynaptic and postsynaptic opioid receptors regulating hypothalamic proopiomelanocortin neurons. | The Journal of neuroscience : the official journal of the Society for Neuroscience 20110105 |
Identification and modulation of voltage-gated Ca2+ currents in zebrafish Rohon-Beard neurons. | Journal of neurophysiology 20110101 |
Sevoflurane inhibits the µ-opioid receptor function expressed in Xenopus oocytes. | Pharmacology 20110101 |
Involvement of peripheral mu opioid receptors in scratching behavior in mice. | European journal of pharmacology 20101215 |
Tolerance to the antinociceptive effect of morphine in the absence of short-term presynaptic desensitization in rat periaqueductal gray neurons. | The Journal of pharmacology and experimental therapeutics 20101201 |
Mu and delta opioid receptors on nociceptors attenuate mechanical hyperalgesia in rat. | Neuroscience 20101124 |
The effects of daikenchuto (DKT) on propulsive motility in the colon. | The Journal of surgical research 20101101 |
CB1 receptors modulate the intake of a sweetened-fat diet in response to μ-opioid receptor stimulation of the nucleus accumbens. | Pharmacology, biochemistry, and behavior 20101101 |
The μ-opioid receptor variant N190K is unresponsive to peptide agonists yet can be rescued by small-molecule drugs. | Molecular pharmacology 20101101 |
Opioid-Induced GABA potentiation after chronic morphine attenuates the rewarding effects of opioids in the ventral tegmental area. | The Journal of neuroscience : the official journal of the Society for Neuroscience 20101020 |
Voltage-dependent kappa-opioid modulation of action potential waveform-elicited calcium currents in neurohypophysial terminals. | Journal of cellular physiology 20101001 |
Differential modulation of N-type calcium channels by micro-opioid receptors in oxytocinergic versus vasopressinergic neurohypophysial terminals. | Journal of cellular physiology 20101001 |
Morphine induces the release of CCL5 from astrocytes: potential neuroprotective mechanism against the HIV protein gp120. | Glia 20101001 |
Depression of cough reflex by microinjections of antitussive agents into caudal ventral respiratory group of the rabbit. | Journal of applied physiology (Bethesda, Md. : 1985) 20101001 |
Implication of dopaminergic projection from the ventral tegmental area to the anterior cingulate cortex in μ-opioid-induced place preference. | Addiction biology 20101001 |
Opioid inhibition of N-type Ca2+ channels and spinal analgesia couple to alternative splicing. | Nature neuroscience 20101001 |
High-fat intake induced by mu-opioid activation of the nucleus accumbens is inhibited by Y1R-blockade and MC3/4R- stimulation. | Brain research 20100902 |
Src family kinases mediate the inhibition of substance P release in the rat spinal cord by μ-opioid receptors and GABA(B) receptors, but not α2 adrenergic receptors. | The European journal of neuroscience 20100901 |
beta-Arrestin 2-mediated heterologous desensitization of IGF-IR by prolonged exposure of SH-SY5Y neuroblastoma cells to a mu opioid agonist. | FEBS letters 20100820 |
G-protein-independent modulation of P-type calcium channels by mu-opioids in Purkinje neurons of rat. | Neuroscience letters 20100816 |
Characteristics of tolerance in the guinea pig ileum produced by chronic in vivo exposure to opioid versus cannabinoid agonists. | Biochemical pharmacology 20100815 |
Ethanol blocks long-term potentiation of GABAergic synapses in the ventral tegmental area involving mu-opioid receptors. | Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20100801 |
Ex vivo delta opioid receptor autoradiography: CNS receptor occupancy of two novel compounds over their antihyperalgesic dose range. | Pharmacology, biochemistry, and behavior 20100801 |
micro-Opioid receptor stimulation in the medial subnucleus of the tractus solitarius inhibits gastric tone and motility by reducing local GABA activity. | American journal of physiology. Gastrointestinal and liver physiology 20100801 |
Peripheral mu-opioid receptors attenuate the augmented exercise pressor reflex in rats with chronic femoral artery occlusion. | American journal of physiology. Heart and circulatory physiology 20100801 |
Involvement of kappa opioid receptors in the formalin-induced inhibition of analgesic tolerance to morphine via suppression of conventional protein kinase C activation. | The Journal of pharmacy and pharmacology 20100801 |
Long-term adaptation to high doses of morphine causes desensitization of mu-OR- and delta-OR-stimulated G-protein response in forebrain cortex but does not decrease the amount of G-protein alpha subunits. | Medical science monitor : international medical journal of experimental and clinical research 20100801 |
Methylxanthine reversal of opioid-evoked inspiratory depression via phosphodiesterase-4 blockade. | Respiratory physiology & neurobiology 20100731 |
Modulation of feeding and locomotion through mu and delta opioid receptor signaling in the nucleus accumbens. | Neuropeptides 20100601 |
Agonist-selective dynamic compartmentalization of human Mu opioid receptor as revealed by resolutive FRAP analysis. | The Journal of biological chemistry 20100507 |
Opioids affect focal contact-mediated cell-substrate adhesion. | European journal of cancer prevention : the official journal of the European Cancer Prevention Organisation (ECP) 20100501 |
Correlation of the time course of development and decay of tolerance to morphine with alterations in sodium pump protein isoform abundance. | Biochemical pharmacology 20100401 |
Agonist-dependent mu-opioid receptor signaling can lead to heterologous desensitization. | Cellular signalling 20100401 |
Sigma 1 receptor modulation of G-protein-coupled receptor signaling: potentiation of opioid transduction independent from receptor binding. | Molecular pharmacology 20100401 |
Shared mechanisms for opioid tolerance and a transition to chronic pain. | The Journal of neuroscience : the official journal of the Society for Neuroscience 20100331 |
Opioid-induced long-term potentiation in the spinal cord is a presynaptic event. | The Journal of neuroscience : the official journal of the Society for Neuroscience 20100324 |
Preference for a high fat diet, but not hyperphagia following activation of mu opioid receptors is blocked in AgRP knockout mice. | Brain research 20100304 |
Phosphorylation of the mu-opioid receptor at tyrosine 166 (Tyr3.51) in the DRY motif reduces agonist efficacy. | Molecular pharmacology 20100301 |
The effect of protein kinase C and G protein-coupled receptor kinase inhibition on tolerance induced by mu-opioid agonists of different efficacy. | The Journal of pharmacology and experimental therapeutics 20100301 |
Nociceptive behaviour upon modulation of mu-opioid receptors in the ventrobasal complex of the thalamus of rats. | Pain 20100301 |
Standard opioid agonists activate heteromeric opioid receptors: evidence for morphine and [d-Ala(2)-MePhe(4)-Glyol(5)]enkephalin as selective μ-δ agonists. | ACS chemical neuroscience 20100217 |
Opioids in the hypothalamus control dopamine and acetylcholine levels in the nucleus accumbens. | Brain research 20100202 |
Opioids in the hypothalamic paraventricular nucleus stimulate ethanol intake. | Alcoholism, clinical and experimental research 20100201 |
Differential modulation of mu-opioid receptor signaling to adenylyl cyclase by regulators of G protein signaling proteins 4 or 8 and 7 in permeabilised C6 cells is Galpha subtype dependent. | Journal of neurochemistry 20100201 |
Activation of spinal alpha-2 adrenoceptors, but not mu-opioid receptors, reduces the intrathecal N-methyl-D-aspartate-induced increase in spinal NR1 subunit phosphorylation and nociceptive behaviors in the rat. | Anesthesia and analgesia 20100201 |
Ethanol exposure selectively alters beta-endorphin content but not [3H]-DAMGO binding in discrete regions of the rat brain. | Neuropeptides 20100201 |
Novel approach to demonstrate high efficacy of mu opioids in the rat vas deferens: a simple model of predictive value. | Brain research bulletin 20100115 |
The role of nucleus accumbens adenosine-opioid interaction in mediating palatable food intake. | Brain research 20100108 |
CB1 receptor blockade decreases ethanol intake and associated neurochemical changes in fawn-hooded rats. | Alcoholism, clinical and experimental research 20100101 |
Muscarinic acetylcholine receptor modulation of mu (mu) opioid receptors in adult rat sphenopalatine ganglion neurons. | Journal of neurophysiology 20100101 |
Clinically relevant infusion rates of mu-opioid agonist remifentanil cause bradypnea in decerebrate dogs but not via direct effects in the pre-Bötzinger complex region. | Journal of neurophysiology 20100101 |
Cholecystokinin receptors mediate tolerance to the analgesic effect of TENS in arthritic rats. | Pain 20100101 |
Opiate-induced suppression of rat hypoglossal motoneuron activity and its reversal by ampakine therapy. | PloS one 20100101 |
Modulation by neuropeptide FF of the interaction of mu-opioid (MOP) receptor with G-proteins. | Neurochemistry international 20100101 |
Analysis of the effects of anesthetics and ethanol on mu-opioid receptor. | Journal of pharmacological sciences 20100101 |
The functional antiopioid action of the ventrolateral periaqueductal gray nociceptin/orphanin FQ and nociceptin receptor system underlies DAMGO analgesic tolerance. | Pharmacology 20100101 |
Regulation of mu opioid receptor internalization by the scaffold protein RanBPM. | Neuroscience letters 20091211 |
The unconditioned fear produced by morphine withdrawal is regulated by mu- and kappa-opioid receptors in the midbrain tectum. | Behavioural brain research 20091201 |
Electroacupuncture attenuates visceral hyperalgesia and inhibits the enhanced excitability of colon specific sensory neurons in a rat model of irritable bowel syndrome. | Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society 20091201 |
Feeding association between the nucleus of the solitary tract and the ventral tegmental area. | Appetite 20091201 |
Cocaine-induced mu opioid receptor occupancy within the striatum is mediated by dopamine D2 receptors. | Brain research 20091103 |
Involvement of Ca2+-dependent PKCs in the adaptive changes of mu-opioid pathways to sympathetic denervation in the guinea pig colon. | Biochemical pharmacology 20091101 |
Immunoneutralization of agmatine sensitizes mice to micro-opioid receptor tolerance. | The Journal of pharmacology and experimental therapeutics 20091101 |
Opioid microinjection into raphe magnus modulates cardiorespiratory function in mice and rats. | American journal of physiology. Regulatory, integrative and comparative physiology 20091101 |
Micro-opioid receptor agonist injections into the presumed pre-Botzinger complex and the surrounding region of awake goats do not alter eupneic breathing. | Journal of applied physiology (Bethesda, Md. : 1985) 20091101 |
Opioids in the nucleus accumbens stimulate ethanol intake. | Physiology & behavior 20091019 |
Opioid mu-receptors in medullary raphe region affect the hypoxic ventilation in anesthetized rats. | Respiratory physiology & neurobiology 20090930 |
Purification and functional reconstitution of monomeric mu-opioid receptors: allosteric modulation of agonist binding by Gi2. | The Journal of biological chemistry 20090925 |
Cell aggregation on agar as an indicator for cell-matrix adhesion: effects of opioids. | In vitro cellular & developmental biology. Animal 20090901 |
Involvement of PKC alpha and G-protein-coupled receptor kinase 2 in agonist-selective desensitization of mu-opioid receptors in mature brain neurons. | British journal of pharmacology 20090901 |
Temporal lobe epilepsy causes selective changes in mu opioid and nociceptin receptor binding and functional coupling to G-proteins in human temporal neocortex. | Neurobiology of disease 20090901 |
Effects of opioid receptor activation on thermal antinociception in red-eared slider turtles (Trachemys scripta). | American journal of veterinary research 20090901 |
Activating mu-opioid receptors in the lateral parabrachial nucleus increases c-Fos expression in forebrain areas associated with caloric regulation, reward and cognition. | Neuroscience 20090818 |
Capsaicin-evoked iCGRP release from human dental pulp: a model system for the study of peripheral neuropeptide secretion in normal healthy tissue. | Pain 20090801 |
CB1 receptor-independent actions of SR141716 on G-protein signaling: coapplication with the mu-opioid agonist Tyr-D-Ala-Gly-(NMe)Phe-Gly-ol unmasks novel, pertussis toxin-insensitive opioid signaling in mu-opioid receptor-Chinese hamster ovary cells. | The Journal of pharmacology and experimental therapeutics 20090801 |
Behavioral characterization of amygdala involvement in mediating intra-accumbens opioid-driven feeding behavior. | Behavioral neuroscience 20090801 |
Induction of synaptic long-term potentiation after opioid withdrawal. | Science (New York, N.Y.) 20090710 |
Convergent, not serial, striatal and pallidal circuits regulate opioid-induced food intake. | Neuroscience 20090707 |
Differential modulation of mu- and delta-opioid receptor agonists by endogenous RGS4 protein in SH-SY5Y cells. | The Journal of biological chemistry 20090703 |
Lung respiratory rhythm and pattern generation in the bullfrog: role of neurokinin-1 and mu-opioid receptors. | Journal of comparative physiology. B, Biochemical, systemic, and environmental physiology 20090701 |
Role of mu- and delta-opioid receptors in the nucleus accumbens in cocaine-seeking behavior. | Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20090701 |
Delta receptors are required for full inhibitory coupling of mu-receptors to voltage-dependent Ca(2+) channels in dorsal root ganglion neurons. | Molecular pharmacology 20090701 |
Inhibition of EGF-induced ERK/MAP kinase-mediated astrocyte proliferation by mu opioids: integration of G protein and beta-arrestin 2-dependent pathways. | Journal of neurochemistry 20090701 |
Regulation of interleukin-1beta and interleukin-8 production by agonists of mu and delta opiate receptors in vitro. | Neuroscience and behavioral physiology 20090701 |
Mu opioid receptor modulation of somatodendritic dopamine overflow: GABAergic and glutamatergic mechanisms. | The European journal of neuroscience 20090701 |
Activation of mu-opioid receptors in thalamic nucleus submedius depresses bee venom-evoked spinal c-Fos expression and flinching behavior. | Neuroscience 20090630 |
Mouse model of OPRM1 (A118G) polymorphism has sex-specific effects on drug-mediated behavior. | Proceedings of the National Academy of Sciences of the United States of America 20090630 |
Seizure activity involved in the up-regulation of BDNF mRNA expression by activation of central mu opioid receptors. | Neuroscience 20090616 |
Sex differences in the activation of the spinoparabrachial circuit by visceral pain. | Physiology & behavior 20090525 |
Which cue to 'want?' Central amygdala opioid activation enhances and focuses incentive salience on a prepotent reward cue. | The Journal of neuroscience : the official journal of the Society for Neuroscience 20090520 |
Antinociceptive effects of nociceptin/orphanin FQ administered intrathecally in monkeys. | The journal of pain : official journal of the American Pain Society 20090501 |
Activation of opioid micro-receptors in medullary raphe depresses sighs. | American journal of physiology. Regulatory, integrative and comparative physiology 20090501 |
A functional link between T-type calcium channels and mu-opioid receptor expression in adult primary sensory neurons. | Journal of neurochemistry 20090501 |
Functional interaction between TRPV1 and mu-opioid receptors in the descending antinociceptive pathway activates glutamate transmission and induces analgesia. | Journal of neurophysiology 20090501 |
Comparison of five benzodiazepine-receptor agonists on buprenorphine-induced mu-opioid receptor regulation. | Journal of pharmacological sciences 20090501 |
Neuropeptide modulation of a lumbar spinal reflex: potential implications for female sexual function. | The journal of sexual medicine 20090401 |
Neutral antagonist activity of naltrexone and 6beta-naltrexol in naïve and opioid-dependent C6 cells expressing a mu-opioid receptor. | British journal of pharmacology 20090401 |
Shadows across mu-Star? Constitutively active mu-opioid receptors revisited. | British journal of pharmacology 20090401 |
GABA and opioid mechanisms of the central amygdala underlie the withdrawal-potentiated startle from acute morphine. | Progress in neuro-psychopharmacology & biological psychiatry 20090317 |
A common human micro-opioid receptor genetic variant diminishes the receptor signaling efficacy in brain regions processing the sensory information of pain. | The Journal of biological chemistry 20090306 |
p38 MAPK and beta-arrestin 2 mediate functional interactions between endogenous micro-opioid and alpha2A-adrenergic receptors in neurons. | The Journal of biological chemistry 20090306 |
G proteins in rat prefrontal cortex (PFC) are differentially activated as a function of oxygen status and PFC region. | Journal of chemical neuroanatomy 20090301 |
Allosteric modulation of metabotropic glutamate receptor 5 affects phosphorylation, internalization, and desensitization of the micro-opioid receptor. | Neuropharmacology 20090301 |
Epileptiform synchronization in the cingulate cortex. | Epilepsia 20090301 |
Beta-endorphin fragments DTgammaE and DEgammaE reduced morphine inhibition of electrically-induced contractions and opiate withdrawal. | Medicinal chemistry (Shariqah (United Arab Emirates)) 20090301 |
Morphine increases brain levels of ferritin heavy chain leading to inhibition of CXCR4-mediated survival signaling in neurons. | The Journal of neuroscience : the official journal of the Society for Neuroscience 20090225 |
Activation of micro, delta or kappa opioid receptors by DAMGO, DPDPE, U-50488 or U-69593 respectively causes antinociception in the formalin test in the naked mole-rat (Heterocephalus glaber). | Pharmacology, biochemistry, and behavior 20090201 |
Muscarinic receptor antagonism causes a functional alteration in nucleus accumbens mu-opiate-mediated feeding behavior. | Behavioural brain research 20090130 |
Morphine enhances microglial migration through modulation of P2X4 receptor signaling. | The Journal of neuroscience : the official journal of the Society for Neuroscience 20090128 |
Binding studies of novel, non-mammalian enkephalins, structures predicted from frog and lungfish brain cDNA sequences. | Neuroscience 20090123 |
Neurokinin 1 receptors regulate morphine-induced endocytosis and desensitization of mu-opioid receptors in CNS neurons. | The Journal of neuroscience : the official journal of the Society for Neuroscience 20090107 |
Persistent inflammatory pain decreases the antinociceptive effects of the mu opioid receptor agonist DAMGO in the locus coeruleus of male rats. | Neuropharmacology 20090101 |
[Mu-opioidergic immunomodulation: the neurochemical basis]. | Uspekhi fiziologicheskikh nauk 20090101 |
Respiratory pattern in midline-lesioned brainstems and hemibrainstems from adult turtles. | Respiratory physiology & neurobiology 20081231 |
Effect of agmatine on DAMGO-induced mu-opioid receptor down-regulation and internalization via activation of IRAS, a candidate for imidazoline I(1) receptor. | European journal of pharmacology 20081203 |
A pharmacological comparison of the cloned frog and human mu opioid receptors reveals differences in opioid affinity and function. | European journal of pharmacology 20081203 |
Depression of C fibre-evoked spinal field potentials by the spinal delta opioid receptor is enhanced in the spinal nerve ligation model of neuropathic pain: involvement of the mu-subtype. | Neuropharmacology 20081201 |
CB(2) cannabinoid receptor antagonist SR144528 decreases mu-opioid receptor expression and activation in mouse brainstem: role of CB(2) receptor in pain. | Neurochemistry international 20081201 |
A naloxonazine sensitive (mu1 receptor) mechanism in the parabrachial nucleus modulates eating. | Brain research 20081113 |
The role of amygdalar mu-opioid receptors in anxiety-related responses in two rat models. | Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20081101 |
The S218L familial hemiplegic migraine mutation promotes deinhibition of Ca(v)2.1 calcium channels during direct G-protein regulation. | Pflugers Archiv : European journal of physiology 20081101 |
Sustained inhibition of neurotransmitter release from nontransient receptor potential vanilloid type 1-expressing primary afferents by mu-opioid receptor activation-enkephalin in the spinal cord. | The Journal of pharmacology and experimental therapeutics 20081101 |
Inhibitory and excitatory effects of micro-, delta-, and kappa-opioid receptor activation on breathing in awake turtles, Trachemys scripta. | American journal of physiology. Regulatory, integrative and comparative physiology 20081101 |
G protein betagamma subunits modulate the number and nature of exocytotic fusion events in adrenal chromaffin cells independent of calcium entry. | Journal of neurophysiology 20081101 |
mu-Opioid receptor forms a functional heterodimer with cannabinoid CB1 receptor: electrophysiological and FRET assay analysis. | Journal of pharmacological sciences 20081101 |
Morphine attenuates the expression of sensitization to ethanol, but opioid antagonists do not. | Neuroscience 20081028 |
Activation of the mu opioid receptor involves conformational rearrangements of multiple transmembrane domains. | Biochemistry 20081007 |
Filamin A mutant lacking actin-binding domain restores mu opioid receptor regulation in melanoma cells. | Neurochemical research 20081001 |
Mu-opioid receptor activation in live cells. | FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20081001 |
Differential activation and trafficking of micro-opioid receptors in brain slices. | Molecular pharmacology 20081001 |
Capsaicin inhibits the in vitro binding of peptides selective for mu- and kappa-opioid, and nociceptin-receptors. | Brain research bulletin 20080930 |
Activating parabrachial cannabinoid CB1 receptors selectively stimulates feeding of palatable foods in rats. | The Journal of neuroscience : the official journal of the Society for Neuroscience 20080924 |
Differential effects of opioid agonists on G protein expression in CHO cells expressing cloned human opioid receptors. | Brain research bulletin 20080905 |
Morphine-induced mu-opioid receptor rapid desensitization is independent of receptor phosphorylation and beta-arrestins. | Cellular signalling 20080901 |
Possible involvement of dynorphin A release via mu1-opioid receptor on supraspinal antinociception of endomorphin-2. | Peptides 20080901 |
Spatial information processing consequences of DAMGO injections into the dorsal striatum. | Neurobiology of learning and memory 20080901 |
Involvement of kappa opioid receptors in the inhibition of receptor desensitization and PKC activation induced by repeated morphine treatment. | The Journal of pharmacy and pharmacology 20080901 |
Acute delta- and kappa-opioid agonist pretreatment potentiates opioid antagonist-induced suppression of water consumption. | Brain research bulletin 20080815 |
Opioid activation in the lateral parabrachial nucleus induces hypertonic sodium intake. | Neuroscience 20080813 |
Insulin acts at different CNS sites to decrease acute sucrose intake and sucrose self-administration in rats. | American journal of physiology. Regulatory, integrative and comparative physiology 20080801 |
Shell/core differences in mu- and delta-opioid receptor modulation of dopamine efflux in nucleus accumbens. | Neuropharmacology 20080801 |
Intrathecal clonidine suppresses phosphorylation of the N-methyl-D-aspartate receptor NR1 subunit in spinal dorsal horn neurons of rats with neuropathic pain. | Anesthesia and analgesia 20080801 |
Micro-opioid receptor agonist diminishes POMC gene expression and anorexia by central insulin in neonatal chicks. | Neuroscience letters 20080718 |
Modulation of the cough reflex by antitussive agents within the caudal aspect of the nucleus tractus solitarii in the rabbit. | American journal of physiology. Regulatory, integrative and comparative physiology 20080701 |
[Regulation of IL-1beta and IL-8 production by mu-, delta-opiate receptors agonists in vitro]. | Rossiiskii fiziologicheskii zhurnal imeni I.M. Sechenova 20080701 |
Morphine-nicotine interaction in conditioned place preference in mice after chronic nicotine exposure. | European journal of pharmacology 20080610 |
Distinct roles of adenylyl cyclases 1 and 8 in opiate dependence: behavioral, electrophysiological, and molecular studies. | Biological psychiatry 20080601 |
The spinal antinociceptive effects of endomorphins in rats: behavioral and G protein functional studies. | Anesthesia and analgesia 20080601 |
[Analysis of central mechanisms involved in gastric mucosal integrity]. | Neuropsychopharmacologia Hungarica : a Magyar Pszichofarmakologiai Egyesulet lapja = official journal of the Hungarian Association of Psychopharmacology 20080601 |
Effects of chronic treatment with citalopram on cannabinoid and opioid receptor-mediated G-protein coupling in discrete rat brain regions. | Psychopharmacology 20080501 |
Endogenous regulators of G protein signaling differentially modulate full and partial mu-opioid agonists at adenylyl cyclase as predicted by a collision coupling model. | Molecular pharmacology 20080501 |
Constitutive activity of the cannabinoid CB1 receptor regulates the function of co-expressed Mu opioid receptors. | The Journal of biological chemistry 20080425 |
Direct evidence for the involvement of endogenous beta-endorphin in the suppression of the morphine-induced rewarding effect under a neuropathic pain-like state. | Neuroscience letters 20080425 |
Multiple actions of spinophilin regulate mu opioid receptor function. | Neuron 20080424 |
Ethanol dually modulates GABAergic synaptic transmission onto dopaminergic neurons in ventral tegmental area: role of mu-opioid receptors. | Neuroscience 20080422 |
Presynaptic actions of opioid receptor agonists in ventromedial hypothalamic neurons in estrogen- and oil-treated female mice. | Neuroscience 20080409 |
Agonist-specific down regulation of mu-opioid receptors: Different cellular pathways are activated by different opioid agonists. | Life sciences 20080409 |
DAMGO-induced expression of chemokines and chemokine receptors: the role of TGF-beta1. | Journal of leukocyte biology 20080401 |
Opioid modulation of ferret vagal afferent mechanosensitivity. | American journal of physiology. Gastrointestinal and liver physiology 20080401 |
Sex-dependent effects of periadolescent exposure to the cannabinoid agonist CP-55,940 on morphine self-administration behaviour and the endogenous opioid system. | Neuropharmacology 20080401 |
Acute amphetamine exposure selectively desensitizes kappa-opioid receptors in the nucleus accumbens. | Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20080301 |
ATP sensitivity of preBötzinger complex neurones in neonatal rat in vitro: mechanism underlying a P2 receptor-mediated increase in inspiratory frequency. | The Journal of physiology 20080301 |
GTPgammaS incorporation in the rat brain: a study on mu-opioid receptors and CXCR4. | Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology 20080301 |
Peripherally-acting opioids. | Pain physician 20080301 |
The effects of local perfusion of DAMGO on extracellular GABA and glutamate concentrations in the rostral ventromedial medulla. | Journal of neurochemistry 20080201 |
Modulation of extracellular signal-regulated kinase (ERK) by opioid and cannabinoid receptors that are expressed in the same cell. | Brain research 20080116 |
Layer selective presynaptic modulation of excitatory inputs to hippocampal cornu Ammon 1 by mu-opioid receptor activation. | Neuroscience 20080102 |
Noladin ether, a putative endocannabinoid, inhibits mu-opioid receptor activation via CB2 cannabinoid receptors. | Neurochemistry international 20080101 |
Manipulation of fatty acid amide hydrolase functional activity alters sensitivity and dependence to ethanol. | Journal of neurochemistry 20080101 |
Activation of mu-opioid receptor selectively potentiates NMDA-induced outward currents in rat locus coeruleus neurons. | Neuroscience research 20080101 |
Opioid regulation of spinal cord plasticity: evidence the kappa-2 opioid receptor agonist GR89696 inhibits learning within the rat spinal cord. | Neurobiology of learning and memory 20080101 |
Modulation of Ca2+ channel current by mu opioid receptors in prefrontal cortex pyramidal neurons in rats. | Acta neurobiologiae experimentalis 20080101 |
Comparison of liquid chromatography-mass spectrometry and radioimmunoassay for measurement of fentanyl and determination of pharmacokinetics in equine plasma. | Journal of analytical toxicology 20080101 |
Opioid-induced depression in the lamprey respiratory network. | Neuroscience 20071212 |
Differential effects of mu-opioid receptor agonists in a hippocampal hypoxia/hypoglycemia model. | Brain research 20071205 |
Mu opioid receptor mutant, T394A, abolishes opioid-mediated adenylyl cyclase superactivation. | Neuroreport 20071203 |
Maternal separation leads to persistent reductions in pain sensitivity in female rats. | The journal of pain : official journal of the American Pain Society 20071201 |
RGS14 prevents morphine from internalizing Mu-opioid receptors in periaqueductal gray neurons. | Cellular signalling 20071201 |
Activity of murine raphe magnus cells predicts tachypnea and on-going nociceptive responsiveness. | Journal of neurophysiology 20071201 |
Trafficking of preassembled opioid mu-delta heterooligomer-Gz signaling complexes to the plasma membrane: coregulation by agonists. | Biochemistry 20071113 |
[Opioids and spinal analgesia]. | Masui. The Japanese journal of anesthesiology 20071101 |
Differential presynaptic effects of opioid agonists on Adelta- and C-afferent glutamatergic transmission to the spinal dorsal horn. | Anesthesiology 20071101 |
Chronic morphine treatment up-regulates mu opioid receptor binding in cells lacking filamin A. | Brain research 20071026 |
DAMGO and 6beta-glycine substituted 14-O-methyloxymorphone but not morphine show peripheral, preemptive antinociception after systemic administration in a mouse visceral pain model and high intrinsic efficacy in the isolated rat vas deferens. | Brain research bulletin 20071019 |
Low dose combination of morphine and delta9-tetrahydrocannabinol circumvents antinociceptive tolerance and apparent desensitization of receptors. | European journal of pharmacology 20071001 |
The single nucleotide polymorphism A118G alters functional properties of the human mu opioid receptor. | Journal of neurochemistry 20071001 |
Novel diastereomeric opioid tetrapeptides exhibit differing pharmacological activity profiles. | Brain research bulletin 20070914 |
Neurobiology of 50-kHz ultrasonic vocalizations in rats: electrode mapping, lesion, and pharmacology studies. | Behavioural brain research 20070904 |
The differential contribution of dopamine D(1) and D (2) receptors to mu-opioidergic immunomodulation. | Neuroscience and behavioral physiology 20070901 |
Attenuation of vascular permeability by methylnaltrexone: role of mOP-R and S1P3 transactivation. | American journal of respiratory cell and molecular biology 20070801 |
Mechanisms responsible for the enhanced antinociceptive effects of micro-opioid receptor agonists in the rostral ventromedial medulla of male rats with persistent inflammatory pain. | The Journal of pharmacology and experimental therapeutics 20070801 |
Glucocorticoids plus opioids up-regulate genes that influence neuronal function. | Cellular and molecular neurobiology 20070801 |
Activation of opioid mu receptors in caudal medullary raphe region inhibits the ventilatory response to hypercapnia in anesthetized rats. | Anesthesiology 20070801 |
Lobeline, a potential pharmacotherapy for drug addiction, binds to mu opioid receptors and diminishes the effects of opioid receptor agonists. | Drug and alcohol dependence 20070710 |
micro-Opioid receptor activation prevents acute hepatic inflammation and cell death. | Gut 20070701 |
Paraventricular opioids alter intake of high-fat but not high-sucrose diet depending on diet preference in a binge model of feeding. | American journal of physiology. Regulatory, integrative and comparative physiology 20070701 |
Effects of ethanol on midbrain neurons: role of opioid receptors. | Alcoholism, clinical and experimental research 20070701 |
Blockade of the nociceptin/orphanin FQ/NOP receptor system in the rat ventrolateral periaqueductal gray potentiates DAMGO analgesia. | Peptides 20070701 |
The chemokine CX3CL1/fractalkine interferes with the antinociceptive effect induced by opioid agonists in the periaqueductal grey of rats. | Brain research 20070611 |
The absence of endogenous beta-endorphin selectively blocks phosphorylation and desensitization of mu opioid receptors following partial sciatic nerve ligation. | Neuroscience 20070608 |
Gene transcription alterations associated with decrease of ethanol intake induced by naltrexone in the brain of Wistar rats. | Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20070601 |
A Tyr-W-MIF-1 analog containing D-Pro2 discriminates among antinociception in mice mediated by different classes of mu-opioid receptors. | European journal of pharmacology 20070601 |
Rapid modulation of micro-opioid receptor signaling in primary sensory neurons. | The Journal of pharmacology and experimental therapeutics 20070601 |
Analgesic tolerance to microinjection of the micro-opioid agonist DAMGO into the ventrolateral periaqueductal gray. | Neuropharmacology 20070601 |
Role of peripheral mu-opioid receptors in inflammatory orofacial muscle pain. | Neuroscience 20070525 |
Effects of local anesthetics on opioid inhibition of calcium current in rat dorsal root ganglion neurons. | Neuroscience letters 20070518 |
Conformational analysis of endomorphin-2 analogs with phenylalanine mimics by NMR and molecular modeling. | Bioorganic & medicinal chemistry 20070515 |
Presynaptic modulation of 5-HT release in the rat septal region. | Neuroscience 20070511 |
Different effects of opioid antagonists on mu-, delta-, and kappa-opioid receptors with and without agonist pretreatment. | The Journal of pharmacology and experimental therapeutics 20070501 |
In vitro characterization of the effects of endomorphin 1 and 2, endogenous ligands for mu-opioid receptors, on mouse colonic motility. | Biochemical pharmacology 20070501 |
Biochemical anti-opioid action of NPFF2 receptors in rat spinal cord. | Neuroscience research 20070501 |
The in vitro pharmacology of the peripherally restricted opioid receptor antagonists, alvimopan, ADL 08-0011 and methylnaltrexone. | Naunyn-Schmiedeberg's archives of pharmacology 20070501 |
Staurosporine differentiation of NPFF2 receptor-transfected SH-SY5Y neuroblastoma cells induces selectivity of NPFF activity towards opioid receptors. | Peptides 20070501 |
Nucleus accumbens opioid signaling conditions short-term flavor preferences. | Neuroscience 20070425 |
Role of kappa and delta opioid receptors in mediating morphine-induced antinociception in morphine-tolerant infant rats. | Brain research 20070420 |
Involvement of endogenous opioid peptides in the antinociception induced by the novel dermorphin tetrapeptide analog amidino-TAPA. | European journal of pharmacology 20070410 |
Differential effects of opioids on sacrocaudal afferent pathways and central pattern generators in the neonatal rat spinal cord. | Journal of neurophysiology 20070401 |
CC12, a high-affinity ligand for [3H]cimetidine binding, is an improgan antagonist. | Neuropharmacology 20070401 |
Endogenous dynorphin in epileptogenesis and epilepsy: anticonvulsant net effect via kappa opioid receptors. | Brain : a journal of neurology 20070401 |
Bidirectional regulation of mu-opioid and CB1-cannabinoid receptor in rats self-administering heroin or WIN 55,212-2. | The European journal of neuroscience 20070401 |
Pain hypersensitivity induced by paradoxical sleep deprivation is not due to altered binding to brain mu-opioid receptors. | Behavioural brain research 20070328 |
Adolescent cannabis exposure alters opiate intake and opioid limbic neuronal populations in adult rats. | Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20070301 |
A comparison of noninternalizing (herkinorin) and internalizing (DAMGO) mu-opioid agonists on cellular markers related to opioid tolerance and dependence. | Synapse (New York, N.Y.) 20070301 |
Modulation of the endogenous opioid system after morphine self-administration and during its extinction: a study in Lewis and Fischer 344 rats. | Neuropharmacology 20070301 |
Effects of mu-opioid receptor modulation on GABAB receptor synaptic function in hippocampal CA1. | Journal of neurophysiology 20070301 |
Alternative splicing controls G protein-dependent inhibition of N-type calcium channels in nociceptors. | Nature neuroscience 20070301 |
Impact of 6-hydroxydopamine lesions and cocaine exposure on mu-opioid receptor expression and regulation of cholinergic transmission in the limbic-prefrontal territory of the rat dorsal striatum. | The European journal of neuroscience 20070301 |
Effects of opioid subtypes on detrusor overactivity in rats with cerebral infarction. | International journal of urology : official journal of the Japanese Urological Association 20070301 |
Suitability of the retrograde tracer Dil for electrophysiological studies of brainstem neurons: adverse ramifications for G-protein coupled receptor agonists. | Journal of neuroscience methods 20070215 |
Opioid limbic circuit for reward: interaction between hedonic hotspots of nucleus accumbens and ventral pallidum. | The Journal of neuroscience : the official journal of the Society for Neuroscience 20070214 |
Functional reduction in mu-opioidergic system in the spinal cord under a neuropathic pain-like state following chronic ethanol consumption in the rat. | Neuroscience 20070209 |
Integrins regulate opioid receptor signaling in trigeminal ganglion neurons. | Neuroscience 20070209 |
Salvinorin A: allosteric interactions at the mu-opioid receptor. | The Journal of pharmacology and experimental therapeutics 20070201 |
Agonist-dependent postsynaptic effects of opioids on miniature excitatory postsynaptic currents in cultured hippocampal neurons. | Journal of neurophysiology 20070201 |
Modulation of Ca2+ channels by heterologously expressed wild-type and mutant human micro-opioid receptors (hMORs) containing the A118G single-nucleotide polymorphism. | Journal of neurophysiology 20070201 |
The inhibitory effect of opioids on HepG2 cells is mediated via interaction with somatostatin receptors. | European journal of pharmacology 20070119 |
Glycosylation improves the central effects of DAMGO. | Chemical biology & drug design 20070101 |
The biochemical analysis of methadone modulation on morphine-induced tolerance and dependence in the rat brain. | Pharmacology 20070101 |
Hypoxia modulates cholinergic but not opioid activation of G proteins in rat hippocampus. | Hippocampus 20070101 |
Morphine induces endocytosis of neuronal mu-opioid receptors through the sustained transfer of Galpha subunits to RGSZ2 proteins. | Molecular pain 20070101 |
Altered gene expression and functional activity of opioid receptors in the cerebellum of CB1 cannabinoid receptor knockout mice after acute treatments with cannabinoids. | Acta biologica Hungarica 20070101 |
Functional interaction between alpha2-adrenoceptors, mu- and kappa-opioid receptors in the guinea pig myenteric plexus: effect of chronic desipramine treatment. | European journal of pharmacology 20061228 |
Black cohosh (Actaea racemosa, Cimicifuga racemosa) behaves as a mixed competitive ligand and partial agonist at the human mu opiate receptor. | Journal of agricultural and food chemistry 20061227 |
Role of CDK5 in neuroprotection from serum deprivation by mu-opioid receptor agonist. | Experimental neurology 20061201 |
Raphe magnus neurons help protect reactions to visceral pain from interruption by cutaneous pain. | Journal of neurophysiology 20061201 |
Pain sensitivity is altered in animals after subchronic ketamine treatment. | Psychopharmacology 20061201 |
The possible involvement of endogenous ligands for mu-, delta- and kappa-opioid receptors in modulating morphine-induced CPP expression in rats. | Peptides 20061201 |
Modulation of neuronal CXCR4 by the micro-opioid agonist DAMGO. | Journal of neurovirology 20061201 |
Mediation of adenylyl cyclase sensitization by PTX-insensitive GalphaoA, Galphai1, Galphai2 or Galphai3. | Journal of neurochemistry 20061201 |
Distinct populations of spinal cord lamina II interneurons expressing G-protein-gated potassium channels. | The Journal of neuroscience : the official journal of the Society for Neuroscience 20061122 |
Nucleus accumbens opioids regulate flavor-based preferences in food consumption. | Neuroscience 20061117 |
Contingent and non-contingent effects of heroin on mu-opioid receptor-containing ventral tegmental area GABA neurons. | Experimental neurology 20061101 |
Methamphetamine-induced behavioral sensitization in mice: alterations in mu-opioid receptor. | Journal of biomedical science 20061101 |
Physiological properties of zebra finch ventral tegmental area and substantia nigra pars compacta neurons. | Journal of neurophysiology 20061101 |
Contribution of spinal mu(1)-opioid receptors and dynorphin B to the antinociception induced by Tyr-d-Arg-Phe-Sar. | Peptides 20061101 |
Role of hepatic opioid receptors in the regulation of bile excretion. | Bulletin of experimental biology and medicine 20061101 |
Mu opioid receptor-effector coupling and trafficking in dorsal root ganglia neurons. | Neuroscience 20061013 |
An antisense oligodeoxynucleotide to the mu opioid receptor attenuates cocaine-induced behavioral sensitization and reward in mice. | Neuroscience 20061013 |
Synthesis and pharmacological studies of new hybrid derivatives of fentanyl active at the mu-opioid receptor and I2-imidazoline binding sites. | Bioorganic & medicinal chemistry 20061001 |
Separation of binding affinity and intrinsic activity of the potent mu-opioid 14-methoxymetopon. | The Journal of pharmacology and experimental therapeutics 20061001 |
Alkylation of opioid receptors by 5'-naltrindole-isothiocyanate injected into the nucleus accumbens of rats: receptor selectivity and anatomical diffusion. | Synapse (New York, N.Y.) 20061001 |
Pharmacological characterization of high-fat feeding induced by opioid stimulation of the ventral striatum. | Physiology & behavior 20060930 |
The mu-opioid receptor subtype is required for the anorectic effect of an opioid receptor antagonist. | European journal of pharmacology 20060918 |
An N-methyl-D-aspartate receptor mediated large, low-frequency, spontaneous excitatory postsynaptic current in neonatal rat spinal dorsal horn neurons. | Neuroscience 20060901 |
11 beta-hydroxysteroid dehydrogenase type 1 induction in the arcuate nucleus by high-fat feeding: A novel constraint to hyperphagia? | Endocrinology 20060901 |
Chronic prevention of mu-opioid receptor (MOR) G-protein coupling in the pontine parabrachial nucleus persistently decreases consumption of standard but not palatable food. | Psychopharmacology 20060901 |
Enhancement of morphine analgesic effect with induction of mu-opioid receptor endocytosis in rats. | Anesthesiology 20060901 |
Opiate pharmacology of intrathecal granulomas. | Anesthesiology 20060901 |
Characterization of neurons in the rat central nucleus of the amygdala: cellular physiology, morphology, and opioid sensitivity. | The Journal of comparative neurology 20060820 |
Differential effects of impaired mitochondrial energy production on the function of mu and delta opioid receptors in neuronal SK-N-SH cells. | Neuroscience letters 20060814 |
Agonist-selective mechanisms of mu-opioid receptor desensitization in human embryonic kidney 293 cells. | Molecular pharmacology 20060801 |
Mu-delta opioid receptor functional interaction: Insight using receptor-G protein fusions. | The Journal of pharmacology and experimental therapeutics 20060801 |
Morphine withdrawal syndrome and its prevention with baclofen: Autoradiographic study of mu-opioid receptors in prepubertal male and female mice. | Synapse (New York, N.Y.) 20060801 |
Respiration-related rhythmic activity in the rostral medulla of newborn rats. | Journal of neurophysiology 20060701 |
Involvement of spinal mu1-opioid receptors on the Tyr-d-Arg-Phe-sarcosine-induced antinociception. | European journal of pharmacology 20060701 |
Presynaptic opioid receptors on noradrenergic and serotonergic neurons in the human as compared to the rat neocortex. | British journal of pharmacology 20060701 |
Competitive displacement binding assay on rat brain sections and using a beta-imager: application to mu-opioid ligands. | Journal of neuroscience methods 20060630 |
Activation of the mu-opiate receptor by Vitex agnus-castus methanol extracts: implication for its use in PMS. | Journal of ethnopharmacology 20060630 |
Effect of opioid receptor ligands injected into the rostral lateral hypothalamus on c-fos and feeding behavior. | Brain research 20060622 |
Opioid mu receptor activation inhibits sodium currents in prefrontal cortical neurons via a protein kinase A- and C-dependent mechanism. | Brain research 20060613 |
The cardiovascular responses to mu opioid agonist and antagonist in conscious normal and obese rats. | Peptides 20060601 |
Partial and full agonism in endomorphin derivatives: comparison by null and operational model. | Peptides 20060601 |
Adenylyl cyclase type II activity is regulated by two different mechanisms: implications for acute and chronic opioid exposure. | Neuropharmacology 20060601 |
Endomorphin-2, an endogenous tetrapeptide, protects against Abeta1-42 in vitro and in vivo. | FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20060601 |
Reduction of lipopolysaccharide-induced interleukin-6 production by the kappa opioid U50,488 in a mouse monocyte-like cell line. | International immunopharmacology 20060601 |
mu opioid and CB1 cannabinoid receptor interactions: reciprocal inhibition of receptor signaling and neuritogenesis. | British journal of pharmacology 20060601 |
Role of delta-opioid receptor function in neurogenesis and neuroprotection. | Journal of neurochemistry 20060601 |
Delta and mu opioid receptors from the brain of a urodele amphibian, the rough-skinned newt Taricha granulosa: cloning, heterologous expression, and pharmacological characterization. | General and comparative endocrinology 20060501 |
In heterozygous GDNF knockout mice the response of striatal dopaminergic system to acute morphine is altered. | Synapse (New York, N.Y.) 20060501 |
Loss of TRPV1-expressing sensory neurons reduces spinal mu opioid receptors but paradoxically potentiates opioid analgesia. | Journal of neurophysiology 20060501 |
Anti-opioid activities of NPFF1 receptors in a SH-SY5Y model. | Peptides 20060501 |
[Differential contribution of dopamine D1 and D2 receptors in the mu-opioidergic immunomodulation]. | Rossiiskii fiziologicheskii zhurnal imeni I.M. Sechenova 20060501 |
In vivo evaluation of (+)-MR200 as a new selective sigma ligand modulating MOP, DOP and KOP supraspinal analgesia. | Life sciences 20060418 |
Opioid receptors in the nucleus accumbens regulate attentional learning in the blocking paradigm. | The Journal of neuroscience : the official journal of the Society for Neuroscience 20060412 |
Opioid-induced regulation of gene expression in PC12 cells stably transfected with mu-opioid receptor. | Neuroscience letters 20060403 |
Chronic pain induces anxiety with concomitant changes in opioidergic function in the amygdala. | Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20060401 |
Mu opioid receptor activation inhibits GABAergic inputs to basolateral amygdala neurons through Kv1.1/1.2 channels. | Journal of neurophysiology 20060401 |
Mu-opioid receptors are involved in the tolerance to nicotine antinociception. | Journal of neurochemistry 20060401 |
Role of phospholipase D2 in the agonist-induced and constitutive endocytosis of G-protein coupled receptors. | Journal of neurochemistry 20060401 |
Evidence for a role of CaMKIV in the development of opioid analgesic tolerance. | The European journal of neuroscience 20060401 |
Modulation of Na, K-ATPase activity by prostaglandin E1 and [D-Ala2,N-Me-Phe4,Gly5-ol]-enkephalin. | Life sciences 20060306 |
Differential activation of G-proteins by mu-opioid receptor agonists. | British journal of pharmacology 20060301 |
Mu-opioid receptor cellular function in the nucleus accumbens is essential for hedonically driven eating. | The European journal of neuroscience 20060301 |
Mesencephalic astrocyte-derived neurotrophic factor enhances nigral gamma-aminobutyric acid release. | Neuroreport 20060227 |
Effects of prenatal cocaine, morphine, or both on postnatal opioid (mu) receptor development. | Life sciences 20060223 |
Estrogen and CCK1 receptor modification of mu-opioid receptor binding in the cortex of female rats. | Brain research 20060216 |
Different effects of opioid and cannabinoid receptor agonists on C-fiber-induced extracellular signal-regulated kinase activation in dorsal horn neurons in normal and spinal nerve-ligated rats. | The Journal of pharmacology and experimental therapeutics 20060201 |
Pharmacological characterization of inhibitory effects of postsynaptic opioid and cannabinoid receptors on calcium currents in neonatal rat nucleus tractus solitarius. | British journal of pharmacology 20060201 |
Cannabidiol is an allosteric modulator at mu- and delta-opioid receptors. | Naunyn-Schmiedeberg's archives of pharmacology 20060201 |
Medullary raphe neurons facilitate brown adipose tissue activation. | The Journal of neuroscience : the official journal of the Society for Neuroscience 20060125 |
Blocking polysynaptic inhibition via opioid receptor activation isolates excitatory synaptic currents without triggering epileptiform activity in organotypic hippocampal slices. | Journal of neuroscience methods 20060115 |
Mu and delta, but not kappa, opioid agonists induce spastic paraparesis after a short period of spinal cord ischaemia in rats. | British journal of anaesthesia 20060101 |
mu-Opioid receptor internalization-dependent and -independent mechanisms of the development of tolerance to mu-opioid receptor agonists: Comparison between etorphine and morphine. | Neuroscience 20060101 |
Inhibition by endomorphin-1 and endomorphin-2 of excitatory transmission in adult rat substantia gelatinosa neurons. | Neuroscience 20060101 |
[The role of monocytes in the effects of beta-endorphin and selective agonists of mu- and delta-Opiate receptors on the proliferative activity of peripheral blood lymphocytes]. | Fiziologiia cheloveka 20060101 |
Methylnaltrexone inhibits opiate and VEGF-induced angiogenesis: role of receptor transactivation. | Microvascular research 20060101 |
Inhibition of AC-II activity following chronic agonist exposure is modulated by phosphorylation. | Journal of molecular neuroscience : MN 20060101 |
N-substituted cis-4a-(3-hydroxyphenyl)-8a-methyloctahydroisoquinolines are opioid receptor pure antagonists. | Journal of medicinal chemistry 20051229 |
Hedonic hot spot in nucleus accumbens shell: where do mu-opioids cause increased hedonic impact of sweetness? | The Journal of neuroscience : the official journal of the Society for Neuroscience 20051214 |
Mu opioid receptor agonist DAMGO-induced suppression of saccharin intake in Lewis and Fischer rats. | Brain research 20051207 |
Antinociception following application of DAMGO to the basolateral amygdala results from a direct interaction of DAMGO with Mu opioid receptors in the amygdala. | Brain research 20051207 |
Nalmefene induced elevation in serum prolactin in normal human volunteers: partial kappa opioid agonist activity? | Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20051201 |
Hypoxia and acidosis increase the secretion of catecholamines in the neonatal rat adrenal medulla: an in vitro study. | American journal of physiology. Cell physiology 20051201 |
A role for the distal carboxyl tails in generating the novel pharmacology and G protein activation profile of mu and delta opioid receptor hetero-oligomers. | The Journal of biological chemistry 20051118 |
Morphine activates Arc expression in the mouse striatum and in mouse neuroblastoma Neuro2A MOR1A cells expressing mu-opioid receptors. | Journal of neuroscience research 20051115 |
Molecular mechanisms involved in the asymmetric interaction between cannabinoid and opioid systems. | Psychopharmacology 20051101 |
Effects of the local administration of selective mu-, delta-and kappa-opioid receptor agonists on osteosarcoma-induced hyperalgesia. | Naunyn-Schmiedeberg's archives of pharmacology 20051101 |
Reduced suppression of CO2-induced ventilatory stimulation by endomorphins relative to morphine. | Brain research 20051019 |
COMT Val108/158Met genotype affects the mu-opioid receptor system in the human brain: evidence from ligand-binding, G-protein activation and preproenkephalin mRNA expression. | NeuroImage 20051015 |
Comparison of the antinociceptive effect of acute morphine in female and male Sprague-Dawley rats using the long-lasting mu-antagonist methocinnamox. | Brain research 20051005 |
Development and validation of a radioreceptor assay for the determination of morphine and its active metabolites in serum. | Journal of pharmaceutical and biomedical analysis 20051004 |
Regulation of the extracellular signal-regulated kinases following acute and chronic opioid treatment. | Cellular and molecular life sciences : CMLS 20051001 |
Kappa- and delta-opioid receptor functional activities are increased in the caudate putamen of cannabinoid CB1 receptor knockout mice. | The European journal of neuroscience 20051001 |
Topography of 3H-DHA, 3H-QNB, 3H-dopamine, and 3H-DAGO binding sites distribution in the central part of the sinoatrial node in rat heart. | Bulletin of experimental biology and medicine 20051001 |
The ventral pallidum and hedonic reward: neurochemical maps of sucrose 'liking' and food intake. | The Journal of neuroscience : the official journal of the Society for Neuroscience 20050921 |
Activation of delta-, kappa-, and mu-opioid receptors induces phosphorylation of tuberin in transfected HEK 293 cells and native cells. | Biochemical and biophysical research communications 20050902 |
Persistent upregulation of mu-opioid, but not adenosine, receptors in brains of long-term withdrawn escalating dose 'binge' cocaine-treated rats. | Synapse (New York, N.Y.) 20050901 |
Opioid tolerance in periaqueductal gray neurons isolated from mice chronically treated with morphine. | British journal of pharmacology 20050901 |
Peripheral axonal injury results in reduced mu opioid receptor pre- and post-synaptic action in the spinal cord. | Pain 20050901 |
Micro-opioid receptor preferentially inhibits oxytocin release from neurohypophysial terminals by blocking R-type Ca2+ channels. | Journal of neuroendocrinology 20050901 |
Activation of GPCRs modulates quantal size in chromaffin cells through G(betagamma) and PKC. | Nature neuroscience 20050901 |
Morphine promotes rapid, arrestin-dependent endocytosis of mu-opioid receptors in striatal neurons. | The Journal of neuroscience : the official journal of the Society for Neuroscience 20050824 |
Acute and chronic administration of clorazepate modifies the cell surface regulation of mu opioid receptors induced by buprenorphine in specific regions of the rat brain. | Brain research 20050809 |
Mu opioid receptor coupling to Gi/o proteins increases during postnatal development in rat brain. | The Journal of pharmacology and experimental therapeutics 20050801 |
Orphanin FQ/nociceptin potentiates [D-Ala2,N-Me-Phe4,Gly5-ol]-enkephalin-Induced mu-opioid receptor phosphorylation. | Molecular pharmacology 20050801 |
Mu and kappa opioid receptors activate ERK/MAPK via different protein kinase C isoforms and secondary messengers in astrocytes. | The Journal of biological chemistry 20050729 |
Mechanisms of mu opioid receptor/G-protein desensitization in brain by chronic heroin administration. | Life sciences 20050722 |
mu-Opioids disinhibit and kappa-opioids inhibit serotonin efflux in the dorsal raphe nucleus. | Brain research 20050705 |
Tramadol produces outward currents by activating mu-opioid receptors in adult rat substantia gelatinosa neurones. | British journal of pharmacology 20050701 |
Sugar solution analgesia: the effects of glucose on expressed mu opioid receptors. | Anesthesia and analgesia 20050701 |
Both kappa and mu opioid agonists inhibit glutamatergic input to ventral tegmental area neurons. | Journal of neurophysiology 20050601 |
Prolonged effects of repeated social defeat stress on mRNA expression and function of mu-opioid receptors in the ventral tegmental area of rats. | Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20050601 |
Functional mu opioid receptors are expressed in cholinergic interneurons of the rat dorsal striatum: territorial specificity and diurnal variation. | The European journal of neuroscience 20050601 |
Alterations of prenatal morphine exposure in mu-opioid receptor density in hypothalamic nuclei associated with sexual behavior. | Brain research bulletin 20050530 |
Maternal deprivation increases vulnerability to morphine dependence and disturbs the enkephalinergic system in adulthood. | The Journal of neuroscience : the official journal of the Society for Neuroscience 20050504 |
Modulation of synaptic transmission in the rat nucleus of the solitary tract by endomorphin-1. | Journal of neurophysiology 20050501 |
Morphine alters the selective association between mu-opioid receptors and specific RGS proteins in mouse periaqueductal gray matter. | Neuropharmacology 20050501 |
STAT5A interacts with and is phosphorylated upon activation of the mu-opioid receptor. | Journal of neurochemistry 20050501 |
Emergence of the pre-Bötzinger respiratory rhythm generator in the mouse embryo. | The Journal of neuroscience : the official journal of the Society for Neuroscience 20050427 |
Spinal G-protein-gated potassium channels contribute in a dose-dependent manner to the analgesic effect of mu- and delta- but not kappa-opioids. | The Journal of neuroscience : the official journal of the Society for Neuroscience 20050406 |
Proopiomelanocortin neurons in nucleus tractus solitarius are activated by visceral afferents: regulation by cholecystokinin and opioids. | The Journal of neuroscience : the official journal of the Society for Neuroscience 20050406 |
Inhibition by spinal mu- and delta-opioid agonists of afferent-evoked substance P release. | The Journal of neuroscience : the official journal of the Society for Neuroscience 20050406 |
Ripple activity in the dentate gyrus of dishinibited hippocampus-entorhinal cortex slices. | Journal of neuroscience research 20050401 |
Reciprocal opioid-opioid interactions between the ventral tegmental area and nucleus accumbens regions in mediating mu agonist-induced feeding in rats. | Peptides 20050401 |
Biological activity of selected tyrosine-containing 2,5-diketopiperazines. | Die Pharmazie 20050401 |
Heterodimerization of mu- and delta-opioid receptors occurs at the cell surface only and requires receptor-G protein interactions. | The Journal of biological chemistry 20050325 |
Induction of delta-opioid receptor function in the midbrain after chronic morphine treatment. | The Journal of neuroscience : the official journal of the Society for Neuroscience 20050323 |
Adenosine contributes to mu-opioid synaptic inhibition in rat substantia gelatinosa in vitro. | Neuroscience letters 20050311 |
A Tyr-W-MIF-1 analog containing D-Pro2 acts as a selective mu2-opioid receptor antagonist in the mouse. | The Journal of pharmacology and experimental therapeutics 20050301 |
Characterisation of opioid receptors involved in modulating circular and longitudinal muscle contraction in the rat ileum. | British journal of pharmacology 20050301 |
Heterodimerization of opioid receptor-like 1 and mu-opioid receptors impairs the potency of micro receptor agonist. | Journal of neurochemistry 20050301 |
Ancient gill and lung oscillators may generate the respiratory rhythm of frogs and rats. | Journal of neurobiology 20050215 |
Neuronal nitric oxide modulates morphine antinociceptive tolerance by enhancing constitutive activity of the mu-opioid receptor. | Biochemical pharmacology 20050215 |
Opiate modulation of monoamines in the chick forebrain: possible role in emotional regulation? | Journal of neurobiology 20050205 |
Endogenous regulator of g protein signaling proteins reduce {mu}-opioid receptor desensitization and down-regulation and adenylyl cyclase tolerance in C6 cells. | The Journal of pharmacology and experimental therapeutics 20050201 |
Effect of the {mu} opioid on excitatory and inhibitory synaptic inputs to periaqueductal gray-projecting neurons in the amygdala. | The Journal of pharmacology and experimental therapeutics 20050201 |
Increased nociceptive response in mice lacking the adenosine A1 receptor. | Pain 20050201 |
Melatonin exerts its analgesic actions not by binding to opioid receptor subtypes but by increasing the release of beta-endorphin an endogenous opioid. | Brain research bulletin 20050130 |
Pharmacologically selective block of mu opioid antinociception by peptide nucleic acid antisense in absence of detectable ex vivo knockdown. | European journal of pharmacology 20050104 |
Receptor endocytosis counteracts the development of opioid tolerance. | Molecular pharmacology 20050101 |
Agonists at mu-opioid receptors spin the wheels to keep the action going. | Molecular pharmacology 20050101 |
Effects of long-term biogenic amine transporter blockade on receptor/G-protein coupling in rat brain. | Neuropharmacology 20050101 |
[Effect of opiod peptides on free radical oxidation in a bone regenerate after fracture]. | Patologicheskaia fiziologiia i eksperimental'naia terapiia 20050101 |
delta-opioid receptor-mediated actions on rostral ventromedial medulla neurons. | Neuroscience 20050101 |
Mu-opioid-mediated inhibition of glutamate synaptic transmission in rat central amygdala neurons. | Neuroscience 20050101 |
Opioid receptor stimulation does not affect cellular hypoxia-induced gene responses mediated by hypoxia-inducible factor 1 in cultured cell lines. | Journal of anesthesia 20050101 |
Ultra-low-dose naloxone suppresses opioid tolerance, dependence and associated changes in mu opioid receptor-G protein coupling and Gbetagamma signaling. | Neuroscience 20050101 |
Interactions among mu- and delta-opioid receptors, especially putative delta1- and delta2-opioid receptors, promote dopamine release in the nucleus accumbens. | Neuroscience 20050101 |
Opioid receptor binding characteristics and structure-activity studies of novel tetrapeptides in the TIPP (Tyr-Tic-Phe-Phe) series. | Neuro-Signals 20050101 |
Displacement of opioid receptor binding ligands from the rat brain by N3-(2',5'-dimethoxyphenacyl) arabinofuranosyluracil. | Research communications in molecular pathology and pharmacology 20050101 |
A bi-directional mu-opioid-opioid connection between the nucleus of the accumbens shell and the central nucleus of the amygdala in the rat. | Brain research 20041210 |
Internalization and down-regulation of mu opioid receptors by endomorphins and morphine in SH-SY5Y human neuroblastoma cells. | Brain research 20041203 |
Differential sensitivity of N- and P/Q-type Ca2+ channel currents to a mu opioid in isolectin B4-positive and -negative dorsal root ganglion neurons. | The Journal of pharmacology and experimental therapeutics 20041201 |
Opioid-like actions of neuropeptide Y in rat substantia gelatinosa: Y1 suppression of inhibition and Y2 suppression of excitation. | Journal of neurophysiology 20041201 |
Tolerance develops in spinal cord, but not in brain with chronic [Dmt1]DALDA treatment. | British journal of pharmacology 20041201 |
Mu and delta opioid-stimulated [35S]GTP gamma S binding in brain and spinal cord of polyarthritic rats. | European journal of pharmacology 20041103 |
The stimulatory effect of mu- and delta-opioid receptors on bovine pinealocyte melatonin synthesis. | Journal of pineal research 20041101 |
Hetero-oligomers of alpha2A-adrenergic and mu-opioid receptors do not lead to transactivation of G-proteins or altered endocytosis profiles. | Biochemical Society transactions 20041101 |
Selective postsynaptic inhibition of tonic-firing neurons in substantia gelatinosa by mu-opioid agonist. | Anesthesiology 20041101 |
Baclofen reestablishes micro-opioid receptor levels modified by morphine withdrawal syndrome in either sex. | Synapse (New York, N.Y.) 20041001 |
Peripheral opiate action on afferent fibres supplying the rat intestine. | Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society 20041001 |
Opioid agonist and antagonist treatment differentially regulates immunoreactive mu-opioid receptors and dynamin-2 in vivo. | European journal of pharmacology 20040913 |
Chronic antidepressant treatment causes a selective reduction of mu-opioid receptor binding and functional coupling to G Proteins in the amygdala of fawn-hooded rats. | The Journal of pharmacology and experimental therapeutics 20040901 |
The amygdala is critical for opioid-mediated binge eating of fat. | Neuroreport 20040826 |
Alterations in food intake by opioid and dopamine signaling pathways between the ventral tegmental area and the shell of the nucleus accumbens. | Brain research 20040820 |
Opioid receptors in fast and slow skeletal muscles of normal and dystrophic mice. | Neuroscience letters 20040819 |
Morphine induces terminal micro-opioid receptor desensitization by sustained phosphorylation of serine-375. | The EMBO journal 20040818 |
Activation of protein kinase C antagonizes the opioid inhibition of calcium current in rat spinal dorsal horn neurons. | Brain research 20040813 |
Activation of AP-1 and CRE-dependent gene expression via mu-opioid receptor. | Journal of neurochemistry 20040801 |
Feeding responses to mu-, delta- and kappa-opioid receptor agonists in the meat-type chick. | Pharmacology, biochemistry, and behavior 20040801 |
Modulation of anxiety-related behaviors by mu- and kappa-opioid receptor agonists depends on the social status of mice. | Peptides 20040801 |
Intra-amygdalar injection of DAMGO: effects on c-Fos levels in brain sites associated with feeding behavior. | Brain research 20040723 |
Dual effects of DAMGO [D-Ala2,N-Me-Phe4,Gly5-ol]-enkephalin and CTAP (D-Phe-Cys-Tyr-D-Trp-Arg-Thr-Pen-Thr-NH2) on adenylyl cyclase activity: implications for mu-opioid receptor Gs coupling. | The Journal of pharmacology and experimental therapeutics 20040701 |
The role of central mu opioid receptors in opioid-induced itch in primates. | The Journal of pharmacology and experimental therapeutics 20040701 |
Central effects of the cannabinoid receptor agonist WIN55212-2 on respiratory and cardiovascular regulation in anaesthetised rats. | British journal of pharmacology 20040701 |
Na+ modulation, inverse agonism, and anorectic potency of 4-phenylpiperidine opioid antagonists. | European journal of pharmacology 20040628 |
Activation of mu opioid receptors in the ventrolateral periaqueductal gray inhibits reflex micturition in anesthetized rats. | Neuroscience letters 20040610 |
Opioid peptide receptor studies. 17. Attenuation of chronic morphine effects after antisense oligodeoxynucleotide knock-down of RGS9 protein in cells expressing the cloned Mu opioid receptor. | Synapse (New York, N.Y.) 20040601 |
Role of mu- and delta-opioid receptors in the nucleus accumbens in turning behaviour of rats. | Neuropharmacology 20040601 |
Nitric oxide modulates the physiological control of ciliary activity in the marine mussel Mytilus edulis via morphine: novel mu opiate receptor splice variants. | Neuro endocrinology letters 20040601 |
Activation of mu-opioid receptors inhibits synaptic inputs to spinally projecting rostral ventromedial medulla neurons. | The Journal of pharmacology and experimental therapeutics 20040501 |
Effect of the A118G polymorphism on binding affinity, potency and agonist-mediated endocytosis, desensitization, and resensitization of the human mu-opioid receptor. | Journal of neurochemistry 20040501 |
Endomorphins exit the brain by a saturable efflux system at the basolateral surface of cerebral endothelial cells. | Experimental brain research 20040501 |
Involvement of opioid receptor subtypes in both stimulatory and inhibitory effects of the opioid peptides on prolactin secretion during pregnancy. | Cellular and molecular neurobiology 20040401 |
Increases in food intake or food-seeking behavior induced by GABAergic, opioid, or dopaminergic stimulation of the nucleus accumbens: is it hunger? | Psychopharmacology 20040301 |
Opioid partial agonist effects of 3-O-methylnaltrexone in rhesus monkeys. | The Journal of pharmacology and experimental therapeutics 20040301 |
Opioid-mediated modulation of calcium currents in striatal and pallidal neurons following reserpine treatment: focus on kappa response. | Synapse (New York, N.Y.) 20040301 |
Orexin (hypocretin)/dynorphin neurons control GABAergic inputs to tuberomammillary neurons. | The European journal of neuroscience 20040301 |
DAMGO suppresses both excitatory and inhibitory synaptic transmission in supraoptic neurones of mouse hypothalamic slice preparations. | Journal of neuroendocrinology 20040301 |
Dopamine1 receptor agonists reverse opioid respiratory network depression, increase CO2 reactivity. | Respiratory physiology & neurobiology 20040225 |
A non-peptide substance P antagonist (CP-96,345) inhibits morphine-induced NF-kappa B promoter activation in human NT2-N neurons. | Journal of neuroscience research 20040215 |
Characterization of mu opioid receptor binding and G protein coupling in rat hypothalamus, spinal cord, and primary afferent neurons during inflammatory pain. | The Journal of pharmacology and experimental therapeutics 20040201 |
Phospholipase D2 modulates agonist-induced mu-opioid receptor desensitization and resensitization. | Journal of neurochemistry 20040201 |
[Molecular pharmacology of opioid receptors]. | Nihon yakurigaku zasshi. Folia pharmacologica Japonica 20040201 |
Enhanced morphine withdrawal and micro -opioid receptor G-protein coupling in A2A adenosine receptor knockout mice. | Journal of neurochemistry 20040201 |
Morphine prevents glutamate-induced death of primary rat neonatal astrocytes through modulation of intracellular redox. | Immunopharmacology and immunotoxicology 20040201 |
The influence of opioid peptides on steroidogenesis in porcine granulosa cells. | Reproduction in domestic animals = Zuchthygiene 20040201 |
Activation of mu-opioid receptors excites a population of locus coeruleus-spinal neurons through presynaptic disinhibition. | Brain research 20040130 |
Heterodimerization and cross-desensitization between the mu-opioid receptor and the chemokine CCR5 receptor. | European journal of pharmacology 20040112 |
Functional coupling, desensitization and internalization of virally expressed mu opioid receptors in cultured dorsal root ganglion neurons from mu opioid receptor knockout mice. | Neuroscience 20040101 |
Reduction in [D-Ala2, NMePhe4, Gly-ol5]enkephalin-induced peripheral antinociception in diabetic rats: the role of the L-arginine/nitric oxide/cyclic guanosine monophosphate pathway. | Anesthesia and analgesia 20040101 |
The effect of CNS opioid on autonomic nervous and cardiovascular responses in diet-induced obese rats. | Peptides 20040101 |
[d-Ala2,N-MePhe4,Gly-ol5]enkephalin-induced internalization of the micro opioid receptor in the spinal cord of morphine tolerant rats. | Neuroscience 20040101 |
Opioidergic modulation of excitability of rat trigeminal root ganglion neuron projections to the superficial layer of cervical dorsal horn. | Neuroscience 20040101 |
Neurotransmitters involved in the opioid regulation of prolactin secretion at the end of pregnancy in rats. | Neuroendocrinology 20040101 |
Opioid modulation of GABA release in the rat inferior colliculus. | BMC neuroscience 20040101 |
Enkephalinergic inhibition of raphe pallidus inputs to rat hypoglossal motoneurones in vitro. | Neuroscience 20040101 |
Mu-opioid receptor agonist effects on medullary respiratory neurons in the cat: evidence for involvement in certain types of ventilatory disturbances. | American journal of physiology. Regulatory, integrative and comparative physiology 20031201 |
Comparison of [Dmt1]DALDA and DAMGO in binding and G protein activation at mu, delta, and kappa opioid receptors. | The Journal of pharmacology and experimental therapeutics 20031201 |
DPI-3290 [(+)-3-((alpha-R)-alpha-((2S,5R)-4-allyl-2,5-dimethyl-1-piperazinyl)-3-hydroxybenzyl)-N-(3-fluorophenyl)-N-methylbenzamide]. I. A mixed opioid agonist with potent antinociceptive activity. | The Journal of pharmacology and experimental therapeutics 20031201 |
Antinociceptive effect of morphine, but not mu opioid receptor number, is attenuated in the spinal cord of diabetic rats. | Anesthesiology 20031201 |
Afferent fiber-selective shift in opiate potency following targeted opioid receptor knockdown. | Pain 20031201 |
Lack of mu-opioid receptor-mediated G-protein activation in the spinal cord of mice lacking Exon 1 or Exons 2 and 3 of the MOR-1 gene. | Journal of pharmacological sciences 20031201 |
Evidence for a mu-opioid-opioid connection between the paraventricular nucleus and ventral tegmental area in the rat. | Brain research 20031121 |
Mu-opioid receptor desensitization in mature rat neurons: lack of interaction between DAMGO and morphine. | The Journal of neuroscience : the official journal of the Society for Neuroscience 20031119 |
Phosphoinositide 3-kinase cascade facilitates mu-opioid desensitization in sensory neurons by altering G-protein-effector interactions. | The Journal of neuroscience : the official journal of the Society for Neuroscience 20031112 |
Anti-mu opioid antiserum against the third external loop of the cloned mu-opioid receptor acts as a mu receptor neutral antagonist. | Brain research. Molecular brain research 20031106 |
Kappa-opioid agonists directly inhibit midbrain dopaminergic neurons. | The Journal of neuroscience : the official journal of the Society for Neuroscience 20031105 |
Co-incident signalling between mu-opioid and M3 muscarinic receptors at the level of Ca2+ release from intracellular stores: lack of evidence for Ins(1,4,5)P3 receptor sensitization. | The Biochemical journal 20031101 |
Effects of the opioid antagonist naltrexone on feeding induced by DAMGO in the ventral tegmental area and in the nucleus accumbens shell region in the rat. | American journal of physiology. Regulatory, integrative and comparative physiology 20031101 |
Vivitrex, an injectable, extended-release formulation of naltrexone, provides pharmacokinetic and pharmacodynamic evidence of efficacy for 1 month in rats. | Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20031101 |
Effects of endomorphin on substantia gelatinosa neurons in rat spinal cord slices. | British journal of pharmacology 20031101 |
Neuropeptide FF exerts pro- and anti-opioid actions in the parabrachial nucleus to modulate food intake. | American journal of physiology. Regulatory, integrative and comparative physiology 20031101 |
An orexigenic role for mu-opioid receptors in the lateral parabrachial nucleus. | American journal of physiology. Regulatory, integrative and comparative physiology 20031101 |
Direct evidence for the up-regulation of spinal micro-opioid receptor function after repeated stimulation of kappa-opioid receptors in the mouse. | The European journal of neuroscience 20031101 |
Involvement of protein kinase C in the adaptive changes of cholinergic neurons to sympathetic denervation in the guinea pig myenteric plexus. | Life sciences 20031003 |
Acute ethanol administration transiently decreases [3H]-DAMGO binding to mu opioid receptors in the rat substantia nigra pars reticulata but not in the caudate-putamen. | Neuroscience research 20031001 |
Evidence for a role of dopaminergic mechanisms in the immunostimulating effect of mu-opioid receptor agonist DAGO. | The International journal of neuroscience 20031001 |
Pharmacological characterization of a 7-benzylidenenaltrexone-preferring opioid receptor in porcine ileal submucosa. | British journal of pharmacology 20031001 |
Two distinct forms of desensitization of G-protein coupled inwardly rectifying potassium currents evoked by alkaloid and peptide mu-opioid receptor agonists. | Molecular and cellular neurosciences 20031001 |
The regulation of steroidogenesis by opioid peptides in porcine theca cells. | Animal reproduction science 20030915 |
Mu-opioid-induced desensitization of opioid receptor-like 1 and mu-opioid receptors: differential intracellular signaling determines receptor sensitivity. | The Journal of pharmacology and experimental therapeutics 20030901 |
Glycinergic inputs to cardiac vagal neurons in the nucleus ambiguus are inhibited by nociceptin and mu-selective opioids. | Journal of neurophysiology 20030901 |
mu-Opioid receptor modulates peptide release from rat neurohypophysial terminals by inhibiting Ca(2+) influx. | Journal of neuroendocrinology 20030901 |
Systemic morphine-induced release of serotonin in the rostroventral medulla is not mimicked by morphine microinjection into the periaqueductal gray. | Journal of neurochemistry 20030901 |
Expression of EGFP-amino-tagged human mu opioid receptor in Drosophila Schneider 2 cells: a potential expression system for large-scale production of G-protein coupled receptors. | Protein expression and purification 20030901 |
Roles of alpha1- and alpha2-adrenoceptors in the nucleus raphe magnus in opioid analgesia and opioid abstinence-induced hyperalgesia. | The Journal of neuroscience : the official journal of the Society for Neuroscience 20030827 |
Presynaptic mechanism for anti-analgesic and anti-hyperalgesic actions of kappa-opioid receptors. | The Journal of neuroscience : the official journal of the Society for Neuroscience 20030813 |
Differences of mu-opioid receptors between Lewis and F344 rats. | Life sciences 20030808 |
Characterization of the binding of [3H][Dmt1]H-Dmt-D-Arg-Phe-Lys-NH2, a highly potent opioid peptide. | The Journal of pharmacology and experimental therapeutics 20030801 |
Effects of orexin (hypocretin) on GIRK channels. | Journal of neurophysiology 20030801 |
Painful inflammation-induced increase in mu-opioid receptor binding and G-protein coupling in primary afferent neurons. | Molecular pharmacology 20030801 |
Expression and G-protein coupling of mu-opioid receptors in the spinal cord and dorsal root ganglia of polyarthritic rats. | Neuropeptides 20030801 |
The effect of papaverine on acute opiate withdrawal in guinea pig ileum. | Phytotherapy research : PTR 20030801 |
Effects of single and dual administration of cocaine and ethanol on opioid and ORL1 receptor expression in rat CNS: an autoradiographic study. | Brain research 20030718 |
Studies of micro-, kappa-, and delta-opioid receptor density and G protein activation in the cortex and thalamus of monkeys. | The Journal of pharmacology and experimental therapeutics 20030701 |
Buprenorphine blocks epsilon- and micro-opioid receptor-mediated antinociception in the mouse. | The Journal of pharmacology and experimental therapeutics 20030701 |
Lack of intersite GABA receptor subtype antagonist effects upon mu opioid receptor agonist-induced feeding elicited from either the ventral tegmental area or nucleus accumbens shell in rats. | Physiology & behavior 20030701 |
Ligand-selective activation of mu-oid receptor: demonstrated with deletion and single amino acid mutations of third intracellular loop domain. | The Journal of pharmacology and experimental therapeutics 20030601 |
Heterologous mu-opioid receptor adaptation by repeated stimulation of kappa-opioid receptor: up-regulation of G-protein activation and antinociception. | Journal of neurochemistry 20030601 |
Rhythmic phrenic, intercostal and sympathetic activity in relation to limb and trunk motor activity in spinal cats. | Neuroscience research 20030601 |
Opioid agonists have different efficacy profiles for G protein activation, rapid desensitization, and endocytosis of mu-opioid receptors. | The Journal of biological chemistry 20030523 |
Internalization and recycling of human mu opioid receptors expressed in Sf9 insect cells. | Life sciences 20030523 |
Effect of strain and sex on mu opioid receptor-mediated G-protein activation in rat brain. | Brain research bulletin 20030515 |
Anti-inflammatory properties of the mu opioid receptor support its use in the treatment of colon inflammation. | The Journal of clinical investigation 20030501 |
Cellular actions of opioids on periaqueductal grey neurons from C57B16/J mice and mutant mice lacking MOR-1. | British journal of pharmacology 20030501 |
Effects of in vitro and in vivo opioids on the production of IL-12 and IL-10 by murine macrophages. | Annals of the New York Academy of Sciences 20030501 |
Cardiovascular responses to central administration of mu and kappa opioid receptor agonist and antagonist in normal rats. | Peptides 20030501 |
Identity of the putative delta1-opioid receptor as a delta-kappa heteromer in the mouse spinal cord. | European journal of pharmacology 20030425 |
Mu-opioid modulation of HIV-1 coreceptor expression and HIV-1 replication. | Virology 20030425 |
Morphology and axonal arborization of rat spinal inner lamina II neurons hyperpolarized by mu-opioid-selective agonists. | The Journal of comparative neurology 20030407 |
Dermorphin tetrapeptide analogues with 2',6'-dimethylphenylalanine (Dmp) substituted for aromatic amino acids have high mu opioid receptor binding and biological activities. | Bioorganic & medicinal chemistry letters 20030407 |
Hypothalamic proopiomelanocortin neurons are glucose responsive and express K(ATP) channels. | Endocrinology 20030401 |
Roles of protein kinase A and C in the opioid potentiation of the GABAA response in rat periaqueductal gray neuron. | Neuropharmacology 20030401 |
Nucleus accumbens mu-opioids regulate intake of a high-fat diet via activation of a distributed brain network. | The Journal of neuroscience : the official journal of the Society for Neuroscience 20030401 |
Nucleus accumbens opioid, GABaergic, and dopaminergic modulation of palatable food motivation: contrasting effects revealed by a progressive ratio study in the rat. | Behavioral neuroscience 20030401 |
Opioids and the apoptotic pathway in human cancer cells. | Neuropeptides 20030401 |
The effect of endomorphins on the release of 3H-norepinephrine from rat nucleus tractus solitarii slices. | Regulatory peptides 20030328 |
Endogenous RGS protein action modulates mu-opioid signaling through Galphao. Effects on adenylyl cyclase, extracellular signal-regulated kinases, and intracellular calcium pathways. | The Journal of biological chemistry 20030314 |
Mu-opioid receptor activation prevents apoptosis following serum withdrawal in differentiated SH-SY5Y cells and cortical neurons via phosphatidylinositol 3-kinase. | Neuropharmacology 20030301 |
Up-regulation of mu-opioid receptor-mediated G-protein activation in protein kinase Cgamma knockout mice following repeated naloxone treatment. | Neuroscience letters 20030227 |
Naloxone and its quaternary derivative, naloxone methiodide, have differing affinities for mu, delta, and kappa opioid receptors in mouse brain homogenates. | Brain research 20030227 |
The presynaptic modulation of corticostriatal afferents by mu-opioids is mediated by K+ conductances. | European journal of pharmacology 20030221 |
The mu opioid agonist DAMGO stimulates cAMP production in SK-N-SH cells through a PLC-PKC-Ca++ pathway. | Brain research. Molecular brain research 20030220 |
Blockade of mu-opioid receptor-mediated G-protein activation and antinociception by TRK-820 in mice. | European journal of pharmacology 20030207 |
(2S,3R) beta-methyl-2',6'-dimethyltyrosine-L-tetrahydroisoquinoline-3-carboxylic acid [(2S,3R)TMT-L-Tic-OH] is a potent, selective delta-opioid receptor antagonist in mouse brain. | The Journal of pharmacology and experimental therapeutics 20030201 |
Molecular evidence for the functional role of dopamine D3 receptor in the morphine-induced rewarding effect and hyperlocomotion. | The Journal of neuroscience : the official journal of the Society for Neuroscience 20030201 |
Opioid receptor activation attenuates nicotinic enhancement of spontaneous GABA release in lateral spiriform nucleus of the chick. | Brain research 20030124 |
Neurokinin-1 versus mu-opioid receptor binding in rat nucleus tractus solitarius after single and recurrent intermittent hypoxia. | Brain research bulletin 20030115 |
Tolerance and dependence following chronic intracerebroventricular infusions of Tyr-D-Arg2-Phe-Sar4 (TAPS). | European journal of pharmacology 20030110 |
Opioid peptide receptor studies. 16. Chronic morphine alters G-protein function in cells expressing the cloned mu opioid receptor. | Synapse (New York, N.Y.) 20030101 |
Cocaine alters mu but not delta or kappa opioid receptor-stimulated in situ [35S]GTPgammaS binding in rat brain. | Synapse (New York, N.Y.) 20030101 |
Coexpression of delta-opioid receptors with micro receptors in GH3 cells changes the functional response to micro agonists from inhibitory to excitatory. | Molecular pharmacology 20030101 |
Opioid receptor-induced GTPgamma35S binding during mouse development. | Developmental biology 20030101 |
Potency differences for D-Phe-Cys-Tyr-D-Trp-Arg-Thr-Pen-Thr-NH2 as an antagonist of peptide and alkaloid micro-agonists in an antinociception assay. | The Journal of pharmacology and experimental therapeutics 20030101 |
Activity of opioid ligands in cells expressing cloned mu opioid receptors. | BMC pharmacology 20030101 |
Characterization of opioid receptors that modulate nociceptive neurotransmission in the trigeminocervical complex. | British journal of pharmacology 20030101 |
Mild thyroid hormones deficiency modifies benzodiazepine and mu-opioid receptor binding in rats. | Neuropharmacology 20030101 |
Mu opioid receptor signaling in morphine sensitization. | Neuroscience 20030101 |
Ligand-induced mu opioid receptor endocytosis and recycling in enteric neurons. | Neuroscience 20030101 |
Upregulation of mu opioid receptors by voluntary morphine administration in drinking water. | Acta biologica Hungarica 20030101 |
Effect of beta-endorphin and DAGO, a selective agonist of mu-opioid receptors, on the proliferative activity of lymphocytes. | Doklady biological sciences : proceedings of the Academy of Sciences of the USSR, Biological sciences sections 20030101 |
Loss of mu-opioid receptor-mediated G-protein activation in the pons/medulla of mice lacking the exons 2 and 3 of mu-opioid receptor gene. | Neuroscience letters 20021225 |
Modulation of melanocortin-induced changes in spinal nociception by mu-opioid receptor agonist and antagonist in neuropathic rats. | Neuroreport 20021220 |
(-)-Cannabidiol antagonizes cannabinoid receptor agonists and noradrenaline in the mouse vas deferens. | European journal of pharmacology 20021205 |
Opioid agonists differentially regulate mu-opioid receptors and trafficking proteins in vivo. | Molecular pharmacology 20021201 |
The fibroblast growth factor receptor is at the site of convergence between mu-opioid receptor and growth factor signaling pathways in rat C6 glioma cells. | The Journal of pharmacology and experimental therapeutics 20021201 |
Functional mu opioid receptors are reduced in the spinal cord dorsal horn of diabetic rats. | Anesthesiology 20021201 |
Kainic acid modifies mu-receptor binding in young, adult, and elderly rat brain. | Cellular and molecular neurobiology 20021201 |
Opioid receptor subtypes differentially modulate serotonin efflux in the rat central nervous system. | The Journal of pharmacology and experimental therapeutics 20021101 |
Spinal pretreatment with antisense oligodeoxynucleotides against exon-1, -4, or -8 of mu-opioid receptor clone leads to differential loss of spinal endomorphin-1-and endomorphin-2-induced antinociception in the mouse. | The Journal of pharmacology and experimental therapeutics 20021101 |
Induction of G protein-coupled receptor kinases 2 and 3 contributes to the cross-talk between mu and ORL1 receptors following prolonged agonist exposure. | Neuropharmacology 20021101 |
The effect of opioid agonists of delta-class DSLET, mu-class DAMGO, kappa-class U-69593 and an opioid antagonist, naloxone, on MTT activity of NALM-1 leukemic cells. | Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 20021101 |
Turnover of mu-opioid receptors in neuroblastoma cells. | Brain research. Molecular brain research 20021015 |
The local environment at the cytoplasmic end of TM6 of the mu opioid receptor differs from those of rhodopsin and monoamine receptors: introduction of an ionic lock between the cytoplasmic ends of helices 3 and 6 by a L6.30(275)E mutation inactivates the mu opioid receptor and reduces the constitutive activity of its T6.34(279)K mutant. | Biochemistry 20021008 |
Influence of a deletion of protein kinase C gamma isoform in the G-protein activation mediated through opioid receptor-like-1 and mu-opioid receptors in the mouse pons/medulla. | Neuroscience letters 20021004 |
Estrogen modulation of mu-opioid receptor-stimulated [35S]-GTP-gamma-S binding in female rat brain visualized by in vitro autoradiography. | Neuroendocrinology 20021001 |
Dimerization of morphine and orphanin FQ/nociceptin receptors: generation of a novel opioid receptor subtype. | Biochemical and biophysical research communications 20020927 |
Quantitative stoichiometry of G-proteins activated by mu-opioid receptors in postmortem human brain. | European journal of pharmacology 20020927 |
Regulation of dihydropyridine-sensitive Ca(2+) channels during naloxone-induced opioid supersensitivity in rats. | European journal of pharmacology 20020920 |
Sympathetic denervation-induced changes in G protein expression in enteric neurons of the guinea pig colon. | Life sciences 20020913 |
Chronic muscle pain induced by repeated acid Injection is reversed by spinally administered mu- and delta-, but not kappa-, opioid receptor agonists. | The Journal of pharmacology and experimental therapeutics 20020901 |
Lack of the nociceptin receptor does not affect acute or chronic nociception in mice. | Peptides 20020901 |
Orphanin FQ/nociceptin-mediated desensitization of opioid receptor-like 1 receptor and mu opioid receptors involves protein kinase C: a molecular mechanism for heterologous cross-talk. | The Journal of pharmacology and experimental therapeutics 20020801 |
Morphine-3beta-D-glucuronide suppresses inhibitory synaptic transmission in rat substantia gelatinosa. | The Journal of pharmacology and experimental therapeutics 20020801 |
Chronic morphine-induced changes in mu-opioid receptors and G proteins of different subcellular loci in rat brain. | The Journal of pharmacology and experimental therapeutics 20020801 |
Affinities of dihydrocodeine and its metabolites to opioid receptors. | Pharmacology & toxicology 20020801 |
Quantitative autoradiographic mapping of opioid receptors in the brain of delta-opioid receptor gene knockout mice. | Brain research 20020726 |
Brain regional mu-opioid receptor function in rat lines selected for differences in alcohol preference. | European journal of pharmacology 20020719 |
Effect of MK-801 on the antinociceptive effect of [D-Ala(2),N-MePhe(4), Gly-ol(5)]enkephalin in diabetic mice. | European journal of pharmacology 20020712 |
Inhibitory effects of opioids on voltage-dependent Ca(2+) channels and catecholamine secretion in cultured porcine adrenal chromaffin cells. | Brain research 20020628 |
Presynaptic mu-opioid receptors regulate a late step of the secretory process in rat ventral tegmental area GABAergic neurons. | Neuropharmacology 20020601 |
Heterodimerization of somatostatin and opioid receptors cross-modulates phosphorylation, internalization, and desensitization. | The Journal of biological chemistry 20020531 |
Differential effects of chronic antidepressant treatments on micro- and delta-opioid receptors in rat brain. | European journal of pharmacology 20020517 |
Potentiation of the excitatory action of NMDA in ventrolateral periaqueductal gray by the mu-opioid receptor agonist, DAMGO. | Brain research 20020510 |
mu-Opioid receptors desensitize less rapidly than delta-opioid receptors due to less efficient activation of arrestin. | The Journal of biological chemistry 20020503 |
Alterations in food intake elicited by GABA and opioid agonists and antagonists administered into the ventral tegmental area region of rats. | Physiology & behavior 20020501 |
Biosensing of opioids using frog melanophores. | Biosensors & bioelectronics 20020401 |
Characterization of mu, kappa, and delta opioid binding in amphibian whole brain tissue homogenates. | The Journal of pharmacology and experimental therapeutics 20020401 |
Specific expression of spinal Fos after PAR-2 stimulation in mast cell-depleted rats. | Neuroreport 20020325 |
Analysis of opioid receptor subtype antagonist effects upon mu opioid agonist-induced feeding elicited from the ventral tegmental area of rats. | Brain research 20020301 |
Predominance of delta-opioid-binding sites in the porcine enteric nervous system. | The Journal of pharmacology and experimental therapeutics 20020301 |
Pharmacological manipulations of the pedunculopontine tegmental nucleus in the rat reduce self-administration of both nicotine and cocaine. | Psychopharmacology 20020301 |
mu/delta Cooperativity and opposing kappa-opioid effects in nucleus accumbens-mediated antinociception in the rat. | The European journal of neuroscience 20020301 |
Up-regulation of central mu-opioid receptors in a model of hepatic encephalopathy: a potential mechanism for increased sensitivity to morphine in liver failure. | Life sciences 20020222 |
Ginseng and ginsenoside Rg3, a newly identified active ingredient of ginseng, modulate Ca2+ channel currents in rat sensory neurons. | European journal of pharmacology 20020202 |
[Nphe(1)]N/OFQ-(1-13)-NH(2) is a competitive and selective antagonist at nociceptin/orphanin FQ receptors mediating K(+) channel activation in rat periaqueductal gray slices. | Neuropharmacology 20020201 |
Opioid agonists inhibit excitatory neurotransmission in ganglia and at the neuromuscular junction in Guinea pig gallbladder. | Gastroenterology 20020201 |
Change of hyperexcitability of hippocampus by cyclosporin A and its modulatory action by fentanyl. | Journal of Korean medical science 20020201 |
Activation of mu-opioid receptors inhibits lordosis behavior in estrogen and progesterone-primed female rats. | Hormones and behavior 20020201 |
Regulation of opioid receptor trafficking and morphine tolerance by receptor oligomerization. | Cell 20020125 |
Relationship between rate and extent of G protein activation: comparison between full and partial opioid agonists. | The Journal of pharmacology and experimental therapeutics 20020101 |
Morphine tolerance in spinal cord is due to interaction between mu- and delta-receptors. | The Journal of pharmacology and experimental therapeutics 20020101 |
Neuroanatomical localization of receptor-activated G proteins in brain. | Methods in enzymology 20020101 |
Activation of mu-opioid receptors in rat ventrolateral medulla selectively blocks baroreceptor reflexes while activation of delta opioid receptors blocks somato-sympathetic reflexes. | Neuroscience 20020101 |
Mu and Delta opioid receptors activate the same G proteins in human neuroblastoma SH-SY5Y cells. | British journal of pharmacology 20020101 |
Mu and kappa opioid agonists modulate ventral tegmental area input to the ventral pallidum. | The European journal of neuroscience 20020101 |
[Dmt(1)]DALDA is highly selective and potent at mu opioid receptors, but is not cross-tolerant with systemic morphine. | Current medicinal chemistry 20020101 |
[Effect of opioid peptides on the repair regeneration of the bone tissue]. | Arkhiv patologii 20020101 |
Endogenous morphine modulates acute thermonociception in mice. | Journal of neurochemistry 20020101 |
[Opiatergic modulation of cardiac resistance to arrhythmogenic exposures]. | Patologicheskaia fiziologiia i eksperimental'naia terapiia 20020101 |
Implications of phosphoinositide 3-kinase in the mu- and delta-opioid receptor-mediated supraspinal antinociception in the mouse. | Neuroscience 20020101 |
Endomorphin-2 inhibits GABAergic inputs to cardiac parasympathetic neurons in the nucleus ambiguus. | Neuroscience 20020101 |
Expression of calcitonin gene-related peptide, substance P and protein kinase C in cultured dorsal root ganglion neurons following chronic exposure to mu, delta and kappa opiates. | Neuroscience 20020101 |
Antagonistic property of buprenorphine for putative epsilon-opioid receptor-mediated G-protein activation by beta-endorphin in pons/medulla of the mu-opioid receptor knockout mouse. | Neuroscience 20020101 |
[Effect of opioid peptides on proliferation and differentiation of skeletogenic cells of rabbit bone marrow in vitro]. | Tsitologiia 20020101 |
Up-regulation of RGS4 mRNA by opioid receptor agonists in PC12 cells expressing cloned mu- or kappa-opioid receptors. | European journal of pharmacology 20011214 |
Excitatory amino acid receptor subtype agonists induce feeding in the nucleus accumbens shell in rats: opioid antagonist actions and interactions with mu-opioid agonists. | Brain research 20011207 |
Role of extracellular signal-regulated kinases in opioid-induced adenylyl cyclase superactivation in human embryonic kidney 293 cells. | Neuroscience letters 20011204 |
Studies on the antinociceptive effect of [Nphe1]nociceptin(1-13)NH2 in mice. | Neuroscience letters 20011204 |
Colocalization of mu-opioid receptors and activated G-proteins in rat cingulate cortex. | The Journal of pharmacology and experimental therapeutics 20011201 |
Acute antinociceptive tolerance and asymmetric cross-tolerance between endomorphin-1 and endomorphin-2 given intracerebroventricularly in the mouse. | The Journal of pharmacology and experimental therapeutics 20011201 |
Effects of a kappa-receptor agonist U-50488 on bulbar respiratory neurons and its antagonistic action against the mu receptor-induced respiratory depression in decerebrate cats. | Japanese journal of pharmacology 20011201 |
Role of protein kinase C in opioid modulation of glycine-gated Cl(-) current in rat periaqueductal gray neuron. | European journal of pharmacology 20011116 |
Morphine acutely and persistently attenuates nonvesicular GABA release in rat nucleus accumbens. | Synapse (New York, N.Y.) 20011101 |
Discriminative disulfide-bonding affinity labeling of opioid receptor subtypes. | Journal of biochemical and biophysical methods 20011030 |
Dexamethasone modulates hypotension induced by opioids in anaesthetised rats. | European journal of pharmacology 20011026 |
Antagonizing effect of protein kinase C activation on the mu-opioid agonist-induced inhibition of high voltage-activated calcium current in rat periaqueductal gray neuron. | Brain research 20011019 |
Acute ethanol administration differentially modulates mu opioid receptors in the rat meso-accumbens and mesocortical pathways. | Brain research. Molecular brain research 20011019 |
Parallel nociceptive reflex pathways with negative and positive feedback functions to foot extensors in the cat. | The Journal of physiology 20011015 |
Constitutively active mu-opioid receptors inhibit adenylyl cyclase activity in intact cells and activate G-proteins differently than the agonist [D-Ala2,N-MePhe4,Gly-ol5]enkephalin. | The Journal of biological chemistry 20011012 |
Differential in vivo internalization of MOR-1 and MOR-1C by morphine. | Neuroreport 20011008 |
Nociceptin inhibits calcium channel currents in a subpopulation of small nociceptive trigeminal ganglion neurons in mouse. | The Journal of physiology 20011001 |
Synergistic mu-opioid and 5-HT1A presynaptic inhibition of GABA release in rat periaqueductal gray neurons. | Neuropharmacology 20011001 |
The role of the hydrophilic Asn230 residue of the mu-opioid receptor in the potency of various opioid agonists. | British journal of pharmacology 20011001 |
New mu-opioid receptor agonists with piperazine moiety. | Chemical & pharmaceutical bulletin 20011001 |
Up-regulation of spinal mu-opioid receptor function to activate G-protein by chronic naloxone treatment. | Brain research 20010921 |
Differential antinociceptive effects induced by intrathecally administered endomorphin-1 and endomorphin-2 in the mouse. | European journal of pharmacology 20010921 |
Resensitization of blood pressure response to mu-opioid peptide agonists after acute desensitization. | Anesthesia and analgesia 20010901 |
Neurotrophin-3 modulates noradrenergic neuron function and opiate withdrawal. | Molecular psychiatry 20010901 |
Opioid action on respiratory neuron activity of the isolated respiratory network in newborn rats. | Anesthesiology 20010901 |
Gi- and Gs-coupled receptors up-regulate the cAMP cascade to modulate HCN2, but not HCN1 pacemaker channels. | Pflugers Archiv : European journal of physiology 20010901 |
Opioid effects on glucose and eicosanoid metabolism in isolated uterus of ovariectomized and non-ovariectomized restricted diet rats. | Prostaglandins, leukotrienes, and essential fatty acids 20010901 |
Binding of Sp1/Sp3 to the proximal promoter of the hMOR gene is enhanced by DAMGO. | Gene 20010822 |
C-terminal splice variants of the mouse mu-opioid receptor differ in morphine-induced internalization and receptor resensitization. | The Journal of biological chemistry 20010817 |
The kappa-opioid antagonist GNTI reduces U50,488-, DAMGO-, and deprivation-induced feeding, but not butorphanol- and neuropeptide Y-induced feeding in rats. | Brain research 20010803 |
Progesterone blockade of estrogen activation of mu-opioid receptors regulates reproductive behavior. | The Journal of neuroscience : the official journal of the Society for Neuroscience 20010801 |
Impaired inhibitory G-protein function contributes to increased calcium currents in rats with diabetic neuropathy. | Journal of neurophysiology 20010801 |
Cyclic AMP imaging in neurones in brain slice preparations. | Journal of neuroscience methods 20010730 |
Major difference in the expression of delta- and mu-opioid receptors between turtle and rat brain. | The Journal of comparative neurology 20010723 |
Quantitative autoradiographic mapping of the ORL1, mu-, delta- and kappa-receptors in the brains of knockout mice lacking the ORL1 receptor gene. | Brain research 20010706 |
gamma-Aminobutyric acid receptor subtype antagonists differentially alter opioid-induced feeding in the shell region of the nucleus accumbens in rats. | Brain research 20010706 |
L-type and T-type calcium channel blockade potentiate the analgesic effects of morphine and selective mu opioid agonist, but not to selective delta and kappa agonist at the level of the spinal cord in mice. | Pain 20010701 |
In vivo pharmacokinetics of selective mu-opioid peptide agonists. | The Journal of pharmacology and experimental therapeutics 20010701 |
Stimulation of guanosine-5'-o-(3-[35S]thio)triphosphate binding in digitonin-permeabilized C6 rat glioma cells: evidence for an organized association of mu-opioid receptors and G protein. | The Journal of pharmacology and experimental therapeutics 20010701 |
Blockade of opioid receptors in rostral ventral medulla prevents antihyperalgesia produced by transcutaneous electrical nerve stimulation (TENS). | The Journal of pharmacology and experimental therapeutics 20010701 |
Chronic exposure to mu-opioid agonists produces constitutive activation of mu-opioid receptors in direct proportion to the efficacy of the agonist used for pretreatment. | Molecular pharmacology 20010701 |
Functional expression and characterization of a voltage-gated CaV1.3 (alpha1D) calcium channel subunit from an insulin-secreting cell line. | Molecular endocrinology (Baltimore, Md.) 20010701 |
Role of opioid receptors in neurogenic dural vasodilation and sensitization of trigeminal neurones in anaesthetized rats. | British journal of pharmacology 20010701 |
SoRI 9409, a non-peptide opioid mu receptor agonist/delta receptor antagonist, fails to stimulate [35S]-GTP-gamma-S binding at cloned opioid receptors. | Brain research bulletin 20010701 |
Substance P and neurokinin A mediate sensory synaptic transmission in young rat dorsal horn neurons. | Brain research bulletin 20010701 |
Effect of intravenous injection of DAGO on neuronal activity in bulbar cardiovascular center. | Bulletin of experimental biology and medicine 20010701 |
Endomorphin-1: induction of motor behavior and lack of receptor desensitization. | The Journal of neuroscience : the official journal of the Society for Neuroscience 20010615 |
In vitro inhibitory effects of J-113397 on nociceptin/orphanin FQ-stimulated. | Neuroreport 20010613 |
Novel quantitative reverse-transcribed polymerase chain reaction of mu opioid receptor mRNA level. | Brain research. Brain research protocols 20010601 |
Involvement of spinal protein kinase Cgamma in the attenuation of opioid mu-receptor-mediated G-protein activation after chronic intrathecal administration of [D-Ala2,N-MePhe4,Gly-Ol(5)]enkephalin. | The Journal of neuroscience : the official journal of the Society for Neuroscience 20010601 |
Supraspinal delta- and mu-opioid receptors mediate gastric mucosal protection in the rat. | The Journal of pharmacology and experimental therapeutics 20010601 |
Inhibition of calcium channels by opioid- and adenosine-receptor agonists in neurons of the nucleus accumbens. | British journal of pharmacology 20010601 |
Receptor constants for endomorphin-1 and endomorphin-1-ol indicate differences in efficacy and receptor occupancy. | European journal of pharmacology 20010601 |
Differential antagonism by naloxone benzoylhydrazone of the activation of inward rectifying K+ channels by nociceptin and a mu-opioid in rat periaqueductal grey slices. | Naunyn-Schmiedeberg's archives of pharmacology 20010601 |
Functional and anatomical localization of mu opioid receptors in the striatum, amygdala, and extended amygdala of the nonhuman primate. | The Journal of comparative neurology 20010514 |
Discrimination between peptide and non-peptide opioid agonists on the transcription of opioid receptors in two cell lines. | Life sciences 20010504 |
In vivo pharmacological characterization of SoRI 9409, a nonpeptidic opioid mu-agonist/delta-antagonist that produces limited antinociceptive tolerance and attenuates morphine physical dependence. | The Journal of pharmacology and experimental therapeutics 20010501 |
Protein kinase C-mediated inhibition of mu-opioid receptor internalization and its involvement in the development of acute tolerance to peripheral mu-agonist analgesia. | The Journal of neuroscience : the official journal of the Society for Neuroscience 20010501 |
Opioids suppress basal and nicotine-induced catecholamine secretion via a stabilizing effect on actin filaments. | Endocrinology 20010501 |
Respiratory function in adult mice lacking the mu-opioid receptor: role of delta-receptors. | The European journal of neuroscience 20010501 |
[The role of mu- and delta-opiate receptors in resistance of the myocardium to free radical damage]. | Rossiiskii fiziologicheskii zhurnal imeni I.M. Sechenova 20010501 |
[Effect of stimulation of mu-opiate receptors on contractility of the isolated heart in normal oxygenation and during ischemia-reperfusion]. | Rossiiskii fiziologicheskii zhurnal imeni I.M. Sechenova 20010501 |
Phosphorylation of Ser363, Thr370, and Ser375 residues within the carboxyl tail differentially regulates mu-opioid receptor internalization. | The Journal of biological chemistry 20010420 |
Agonist-induced mu opioid receptor phosphorylation and functional desensitization in rat thalamus. | Brain research 20010420 |
The activation of mu opioid receptors promotes a small modulation of calcium currents in rat pallidal neurons. | Brain research 20010406 |
Interaction of co-expressed mu- and delta-opioid receptors in transfected rat pituitary GH(3) cells. | Molecular pharmacology 20010401 |
Activity of mu- and delta-opioid agonists in vas deferens from mice deficient in MOR gene. | British journal of pharmacology 20010401 |
Contribution of endogenous enkephalins to the enhanced analgesic effects of supraspinal mu opioid receptor agonists after inflammatory injury. | The Journal of neuroscience : the official journal of the Society for Neuroscience 20010401 |
Non-opioid actions of lamotrigine within the rat dorsal horn after inflammation and neuropathic nerve damage. | Neuroscience research 20010401 |
Direct autocrine inhibition and cAMP-dependent potentiation of single L-type Ca2+ channels in bovine chromaffin cells. | The Journal of physiology 20010401 |
G protein-coupled receptor kinase 2 mediates mu-opioid receptor desensitization in GABAergic neurons of the nucleus raphe magnus. | Journal of neurochemistry 20010401 |
Effect of centrally administered opioid receptor agonists on CSF and plasma oxytocin concentrations in dogs. | American journal of veterinary research 20010401 |
Quantitative autoradiography of mu-opioid receptors in the CNS of high-alcohol-drinking (HAD) and low-alcohol-drinking (LAD) rats. | Alcoholism, clinical and experimental research 20010401 |
Stimulation of mu and delta-Opiate Receptors and Tolerance of Isolated Heart to Oxidative Stress: the Role of NO-Synthase. | Biochemistry. Biokhimiia 20010401 |
The metabolic evidence of synergistic interaction between DAMGO and DPDPE on undifferentiated SH-SY5Y cells. | Neuroreport 20010326 |
Mu opioid receptor efficacy and potency of morphine-6-glucuronide in neonatal guinea pig brainstem membranes: comparison with transfected CHO cells. | Brain research bulletin 20010315 |
Selective inactivation of guanine-nucleotide-binding regulatory protein (G-protein) alpha and betagamma subunits by urea. | The Biochemical journal 20010301 |
Opioid-mediated facilitation of long-term depression in rat hippocampus. | The Journal of pharmacology and experimental therapeutics 20010301 |
Transport of opioids from the brain to the periphery by P-glycoprotein: peripheral actions of central drugs. | Nature neuroscience 20010301 |
Expression of functional mu-opioid receptors during T cell development. | Journal of neuroimmunology 20010301 |
Neutrophil neutral endopeptidase variation and its regulation by opioid peptides. | International immunopharmacology 20010301 |
Threonine 180 is required for G-protein-coupled receptor kinase 3- and beta-arrestin 2-mediated desensitization of the mu-opioid receptor in Xenopus oocytes. | The Journal of biological chemistry 20010216 |
A single nucleotide polymorphic mutation in the human mu-opioid receptor severely impairs receptor signaling. | The Journal of biological chemistry 20010202 |
Pharmacological effects of naltriben as a ligand for opioid mu and kappa receptors in rat cerebral cortex. | Life sciences 20010202 |
Mu opiates inhibit long-term potentiation induction in the spinal cord slice. | Journal of neurophysiology 20010201 |
G protein activation in rat ponto-mesencephalic nuclei is enhanced by combined treatment with a mu opioid and an adenosine A1 receptor agonist. | Sleep 20010201 |
Interference of biocytin with opioid-evoked hyperpolarization and membrane properties of rat spinal substantia gelatinosa neurons. | Neuroscience letters 20010112 |
Cyclic AMP regulates the calcium transients released from IP(3)-sensitive stores by activation of rat kappa-opioid receptors expressed in CHO cells. | Cell calcium 20010101 |
Direct actions of cannabinoids on synaptic transmission in the nucleus accumbens: a comparison with opioids. | Journal of neurophysiology 20010101 |
Dexamethasone blocking effects on mu- and delta-opioid-induced seizures involves kappa-opioid activity in the rabbit. | Neuropsychobiology 20010101 |
Involvement of pallidothalamic circuitry in working memory. | Neuroscience 20010101 |
Characterization of kappa and delta opioid receptors in isolated organs by using type/subtype selective agonists and antagonists. | Medical science monitor : international medical journal of experimental and clinical research 20010101 |
Nicotine withdrawal hyperalgesia and opioid-mediated analgesia depend on nicotine receptors in nucleus accumbens. | Neuroscience 20010101 |
Activation of central opioid receptors may induce gastric mucosal defence in the rat. | Journal of physiology, Paris 20010101 |
Chronic in utero morphine exposure alters mu-agonist-stimulated [35S]-GTPgammaS binding in neonatal and juvenile guinea pig brainstem regions associated with breathing control. | Neurotoxicology and teratology 20010101 |
Opiates promote T cell apoptosis through JNK and caspase pathway. | Advances in experimental medicine and biology 20010101 |
Crosstalk between chemokine and opioid receptors results in downmodulation of cell migration. | Advances in experimental medicine and biology 20010101 |
[Participation of K(ATP)-channels in cardioprotective effect of mu-opioid receptor agonists in acute ischemia and reperfusion of the isolated heart]. | Eksperimental'naia i klinicheskaia farmakologiia 20010101 |
[State of the opioid system in rats with different sensitivity to ethanol]. | Ukrains'kyi biokhimichnyi zhurnal (1999 ) 20010101 |
Autoradiographic evidence that prolonged withdrawal from intermittent cocaine reduces mu-opioid receptor expression in limbic regions of the rat brain. | Synapse (New York, N.Y.) 20000915 |
Differential cardiorespiratory effects of endomorphin 1, endomorphin 2, DAMGO, and morphine. | American journal of respiratory and critical care medicine 20000901 |
Synaptic actions of neuropeptide FF in the rat parabrachial nucleus: interactions with opioid receptors. | Journal of neurophysiology 20000801 |
5'-Guanidinonaltrindole, a highly selective and potent kappa-opioid receptor antagonist. | European journal of pharmacology 20000512 |
G protein activation by endomorphins in the mouse periaqueductal gray matter. | Journal of biomedical science 20000101 |
Morphine inhibits human microglial cell production of, and migration towards, RANTES. | Journal of psychopharmacology (Oxford, England) 20000101 |
Long-lasting antinociceptive effect of DAMGO chloromethyl ketone in rats. | Peptides 19991101 |
Opioid modulation of calcium current in cultured sensory neurons: mu-modulation of baroreceptor input. | The American journal of physiology 19990801 |
Mu- and delta-opioid receptor agonists inhibit DARPP-32 phosphorylation in distinct populations of striatal projection neurons. | The European journal of neuroscience 19990601 |
Time-dependent differences of repeated administration with Delta9-tetrahydrocannabinol in proenkephalin and cannabinoid receptor gene expression and G-protein activation by mu-opioid and CB1-cannabinoid receptors in the caudate-putamen. | Brain research. Molecular brain research 19990406 |
Spinal analgesic action of endomorphins in acute, inflammatory and neuropathic pain in rats. | European journal of pharmacology 19990219 |
Endomorphins fully activate a cloned human mu opioid receptor. | FEBS letters 19981113 |
Dopamine depletion reorganizes projections from the nucleus accumbens and ventral pallidum that mediate opioid-induced motor activity. | The Journal of neuroscience : the official journal of the Society for Neuroscience 19981001 |
Apparent thermodynamic parameters of ligand binding to the cloned rat mu-opioid receptor. | European journal of pharmacology 19980807 |
Delta opioid receptor enhancement of mu opioid receptor-induced antinociception in spinal cord. | The Journal of pharmacology and experimental therapeutics 19980601 |
Glycine and GABAA receptor-mediated synaptic transmission in rat substantia gelatinosa: inhibition by mu-opioid and GABAB agonists. | The Journal of physiology 19980301 |
Endogenous opioid peptides acting at mu-opioid receptors in the dorsal horn contribute to midbrain modulation of spinal nociceptive neurons. | Journal of neurophysiology 19980201 |
Differential effects of intrathecally administered delta and mu opioid receptor agonists on formalin-evoked nociception and on the expression of Fos-like immunoreactivity in the spinal cord of the rat. | The Journal of pharmacology and experimental therapeutics 19980101 |
Kappa1- and kappa2-opioid receptors mediating presynaptic inhibition of dopamine and acetylcholine release in rat neostriatum. | British journal of pharmacology 19971001 |
Activation of the cloned human kappa opioid receptor by agonists enhances [35S]GTPgammaS binding to membranes: determination of potencies and efficacies of ligands. | The Journal of pharmacology and experimental therapeutics 19970801 |
Differential effects of omega-conotoxin GVIA, nimodipine, calmidazolium and KN-62 injected intrathecally on the antinociception induced by beta-endorphin, morphine and [D-Ala2,N-MePhe4,Gly-ol5]-enkephalin administered intracerebroventricularly in the mouse. | The Journal of pharmacology and experimental therapeutics 19970801 |
Dissociation of tolerance and dependence for opioid peripheral antinociception in rats. | The Journal of neuroscience : the official journal of the Society for Neuroscience 19970515 |
A potent and selective endogenous agonist for the mu-opiate receptor. | Nature 19970403 |
Inhibition of swine microglial cell phagocytosis of Cryptococcus neoformans by femtomolar concentrations of morphine. | Biochemical pharmacology 19970321 |
Multiple receptors involved in peripheral alpha 2, mu, and A1 antinociception, tolerance, and withdrawal. | The Journal of neuroscience : the official journal of the Society for Neuroscience 19970115 |
Opioid peptides: simultaneous delta agonism and mu antagonism in somatostatin analogues. | Peptides 19970101 |
Competitive and non-competitive NMDA antagonists block the development of antinociceptive tolerance to morphine, but not to selective mu or delta opioid agonists in mice. | Pain 19961201 |
A single residue, Lys108, of the delta-opioid receptor prevents the mu-opioid-selective ligand [D-Ala2,N-MePhe4,Gly-ol5]enkephalin from binding to the delta-opioid receptor. | Molecular pharmacology 19961101 |
The mu-opioid receptor antagonist D-Phe-Cys-Tyr-D-Trp-Orn-Thr-Pen-Thr-NH2 (CTOP) [but not D-Phe-Cys-Tyr-D-Trp-Arg-Thr-Pen-Thr-NH2 (CTAP)] produces a nonopioid receptor-mediated increase in K+ conductance of rat locus ceruleus neurons. | Molecular pharmacology 19960901 |
Vincristine hyperalgesia in the rat: a model of painful vincristine neuropathy in humans. | Neuroscience 19960701 |
Differential desensitization of mu- and delta- opioid receptors in selected neural pathways following chronic morphine treatment. | British journal of pharmacology 19960101 |
Low-dose effect of ethanol on locomotor activity induced by activation of the mesolimbic system. | Alcoholism, clinical and experimental research 19950601 |
Electrophysiological demonstration of mu, delta and kappa opioid receptors in the ventral pallidum. | The Journal of pharmacology and experimental therapeutics 19950301 |
Opioid effects on spinal [3H]5-hydroxytryptamine release are not related to their antinociceptive action. | European journal of pharmacology 19950105 |
Acute tolerance to the excitatory effects of opioids in the rat hippocampus. | Journal of neuroscience research 19950101 |
Comparison of prostaglandin E1- and prostaglandin E2-induced hyperalgesia in the rat. | Neuroscience 19940901 |
Differential regulation of mu and delta opiate receptors by morphine, selective agonists and antagonists and differentiating agents in SH-SY5Y human neuroblastoma cells. | The Journal of pharmacology and experimental therapeutics 19940901 |
Evidence for a central long-lasting antinociceptive effect of vapreotide, an analog of somatostatin, involving an opioidergic mechanism. | The Journal of pharmacology and experimental therapeutics 19940401 |
Behavioral and neurochemical studies of opioid effects in the pedunculopontine nucleus and mediodorsal thalamus. | The Journal of pharmacology and experimental therapeutics 19940401 |
Blockade of neurotensin-induced motor activity by inhibition of protein kinase. | Psychopharmacology 19940201 |
Cloning and pharmacological characterization of a rat kappa opioid receptor. | Proceedings of the National Academy of Sciences of the United States of America 19931101 |
Facilitatory modulation of mesolimbic dopamine neuronal activity by a mu-opioid agonist and nicotine as examined with in vivo microdialysis. | Brain research 19931008 |
Differential regulation of adenylyl cyclase activity by mu and delta opioids in rat caudate putamen and nucleus accumbens. | The Journal of pharmacology and experimental therapeutics 19931001 |
Discovery of a novel class of neuromedin B receptor antagonists, substituted somatostatin analogues. | Molecular pharmacology 19931001 |
Behavioral effects of the mu-opioid peptide agonists DAMGO, DALDA, and PL017 on locomotor activities. | Pharmacology, biochemistry, and behavior 19931001 |
Differential involvement of ventral tegmental mu, delta and kappa opioid receptors in modulation of basal mesolimbic dopamine release: in vivo microdialysis studies. | The Journal of pharmacology and experimental therapeutics 19930901 |
Kinetic parameters of antagonism by the delta opioid receptor selective peptide antagonist Boc-Tyr-Pro-Gly-Phe-Leu-Thr against selective and non-selective agonists in the mouse vas deferens. | Neuropeptides 19930801 |
Investigation of the structural parameters involved in the delta-opioid selectivity of several families of opioid peptides. | International journal of peptide and protein research 19930601 |
Go mediates the coupling of the mu opioid receptor to adenylyl cyclase in cloned neural cells and brain. | Proceedings of the National Academy of Sciences of the United States of America 19930501 |
In vivo modulation of gastrointestinal motor activity by Met-enkephalin, morphine and enkephalin analogs in chickens. | Regulatory peptides 19930305 |
Conformationally restricted deltorphin analogues. | Journal of medicinal chemistry 19921016 |
Opioid receptor antagonists discriminate between presynaptic mu and delta receptors and the adenylate cyclase-coupled opioid receptor complex in the brain. | The Journal of pharmacology and experimental therapeutics 19921001 |
Evidence for the implication of phosphoinositol signal transduction in mu-opioid inhibition of DNA synthesis. | Journal of neurochemistry 19920901 |
Modulation of peristalsis in the guinea-pig isolated small intestine by exogenous and endogenous opioids. | British journal of pharmacology 19920801 |
Spinal interactions between opioid and noradrenergic agonists in mice: multiplicativity involves delta and alpha-2 receptors. | The Journal of pharmacology and experimental therapeutics 19920701 |
Limbic thalamus in rabbit: architecture, projections to cingulate cortex and distribution of muscarinic acetylcholine, GABAA, and opioid receptors. | The Journal of comparative neurology 19920508 |
The calcium antagonist diltiazem has antiarrhythmic effects which are mediated in the brain through endogenous opioids. | Neuropharmacology 19920501 |
Feedback inhibition of met-enkephalin release from the rat spinal cord in vivo. | Synapse (New York, N.Y.) 19920501 |
Differential development of beta-endorphin and mu opioid binding sites in mouse brain. | Brain research. Developmental brain research 19920320 |
Inhibition of cholinergic neurotransmission in human airways by opioids. | Journal of applied physiology (Bethesda, Md. : 1985) 19920301 |
Transient expression of opioid receptors in defined regions of developing brain: are embryonic receptors selective? | Journal of neurochemistry 19911201 |
Neurons in the rat arcuate nucleus are hyperpolarized by GABAB and mu-opioid receptor agonists: evidence for convergence at a ligand-gated potassium conductance. | Neuroendocrinology 19911201 |
Binding to opioid receptors of enkephalin derivatives taking alpha-helical conformation and its dimer. | International journal of peptide and protein research 19911001 |
Characterization and distribution of [3H]ohmefentanyl binding sites in the human brain. | Synapse (New York, N.Y.) 19910701 |
Dopaminergic involvement in locomotion elicited from the ventral pallidum/substantia innominata. | Brain research 19910222 |
Different profile of electrocortical power spectrum changes after micro-infusion into the locus coeruleus of selective agonists at various opioid receptor subtypes in rats. | British journal of pharmacology 19901101 |
The effects of opioid peptides on dopamine release in the nucleus accumbens: an in vivo microdialysis study. | Journal of neurochemistry 19901101 |
Effect of acute and daily neurotensin and enkephalin treatments on extracellular dopamine in the nucleus accumbens. | The Journal of neuroscience : the official journal of the Society for Neuroscience 19900901 |
Opioids hyperpolarize beta-endorphin neurons via mu-receptor activation of a potassium conductance. | Neuroendocrinology 19900901 |
Modulation of mu, delta and kappa opioid receptors in rat brain by metal ions and histidine. | Neuropharmacology 19900501 |
Opioids act at mu-receptors to hyperpolarize arcuate neurons via an inwardly rectifying potassium conductance. | Brain research 19900409 |
Cross-linking of human [125I]beta-endorphin to opioid receptors in rat striatal membranes: biochemical evidence for the existence of a mu/delta opioid receptor complex. | The Journal of pharmacology and experimental therapeutics 19900401 |
Enkephalinergic and GABAergic modulation of motor activity in the ventral pallidum. | The Journal of pharmacology and experimental therapeutics 19900301 |
Laminar distributions of muscarinic acetylcholine, serotonin, GABA and opioid receptors in human posterior cingulate cortex. | Neuroscience 19900101 |
Synthesis, biochemical and pharmacological properties of BUBUC, a highly selective and systemically active agonist for in vivo studies of delta-opioid receptors. | Peptides 19900101 |
Centrally administered opioid peptides stimulate saccharin intake in nondeprived rats. | Pharmacology, biochemistry, and behavior 19890801 |
Guanine nucleotide regulation of [125I]beta-endorphin binding to NG108-15 and SK-N-SH cell membranes: specific cation requirements. | Brain research 19890724 |
Dermenkephalin (Tyr-D-Met-Phe-His-Leu-Met-Asp-NH2): a potent and fully specific agonist for the delta opioid receptor. | Molecular pharmacology 19890601 |
Activation of mu opioid receptors in the nucleus raphe dorsalis blocks apomorphine-induced aggression in rats: serotonin appears not to be involved. | Brain research 19890529 |
Opioid inhibition of spontaneously active neurons of the rat arcuate nucleus in vitro. | Brain research bulletin 19890501 |
Peripheral opioid receptors mediating antinociception in inflammation. Evidence for involvement of mu, delta and kappa receptors. | The Journal of pharmacology and experimental therapeutics 19890301 |
Mu and delta opioid receptors inhibit serotonin release in rat hippocampus. | The Journal of pharmacology and experimental therapeutics 19890101 |
Involvement of the mu-opiate receptor in peripheral analgesia. | Neuroscience 19890101 |
Selective tolerance at mu and kappa opioid receptors modulating norepinephrine release in guinea pig cortex. | The Journal of pharmacology and experimental therapeutics 19881201 |
Development of conformationally constrained linear peptides exhibiting a high affinity and pronounced selectivity for delta opioid receptors. | Journal of medicinal chemistry 19881001 |
Inhibition of exocrine pancreatic secretion by opiates is mediated by suppression of cholinergic transmission: characterization of receptor subtypes. | The Journal of pharmacology and experimental therapeutics 19880701 |
Comparative binding of mu and delta selective ligands in whole brain and pons/medulla homogenates from rat: affinity profiles of fentanyl derivatives. | Neuropharmacology 19880401 |
[3H][D-Ser2(O-tert-butyl),Leu5]enkephalyl-Thr6 and [D-Ser2(O-tert-butyl),Leu5]enkephalyl-Thr6(O-tert-butyl). Two new enkephalin analogs with both a good selectivity and a high affinity toward delta-opioid binding sites. | The Journal of biological chemistry 19880325 |
Affinity crosslinking of 125I-labeled human beta-endorphin to cell lines possessing either mu- or delta-type opioid binding sites. | Brain research 19880209 |
Roles of central and peripheral mu, delta and kappa opioid receptors in the mediation of gastric acid secretory effects in the rat. | The Journal of pharmacology and experimental therapeutics 19880201 |
Sensitization occurs to the locomotor effects of morphine and the specific mu opioid receptor agonist, DAGO, administered repeatedly to the ventral tegmental area but not to the nucleus accumbens. | Brain research 19870804 |
Mu and delta receptors belong to a family of receptors that are coupled to potassium channels. | Proceedings of the National Academy of Sciences of the United States of America 19870801 |
Opioid receptor regulation of the release of norepinephrine in brain. | Neuropharmacology 19870701 |
Opioid receptor subtypes in the rat spinal cord: electrophysiological studies with mu- and delta-opioid receptor agonists in the control of nociception. | Brain research 19870609 |
Morphine and enkephalins potently inhibit [3H]noradrenaline release from rat brain cortex synaptosomes: further evidence for a presynaptic localization of mu-opioid receptors. | Journal of neurochemistry 19870401 |
Mu opioid receptor involvement in enkephalin activation of dopamine neurons in the ventral tegmental area. | The Journal of pharmacology and experimental therapeutics 19870401 |
Opposite effects of delta and mu opioid receptor agonists on the in vitro release of substance P-like material from the rat spinal cord. | Journal of neurochemistry 19870201 |
Effects of a novel opioid peptide antagonist on rat bladder motility in vivo. | Peptides 19870101 |
Evidence that endogenous enkephalins produce delta-opiate receptor mediated neuronal inhibitions in rat dorsal horn. | Neuroscience letters 19861212 |
Multiple opiate binding sites in the central nervous system of the rabbit. Large predominance of a mu subtype in the cerebellum and characterization of a kappa subtype in the thalamus. | Molecular pharmacology 19830701 |
Differential cardiovascular effects of mu, delta and kappa opiate agonists at discrete hypothalamic sites in the anesthetized rat. | Life sciences 19821101 |
Analogues of beta-LPH61-64 possessing selective agonist activity at mu-opiate receptors. | European journal of pharmacology 19810409 |
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