200,000+ products from a single source!
sales@angenechem.com
1007-18-7 | 3-Pyridinecarboxamide, 1,6-dihydro-N-methyl-6-oxo-
CAS No: 1007-18-7 Catalog No: AG0002NM MDL No:MFCD11174156
Product Description
Catalog Number:
AG0002NM
Chemical Name:
3-Pyridinecarboxamide, 1,6-dihydro-N-methyl-6-oxo-
CAS Number:
1007-18-7
Molecular Formula:
C7H8N2O2
Molecular Weight:
152.1506
MDL Number:
MFCD11174156
IUPAC Name:
N-methyl-6-oxo-1H-pyridine-3-carboxamide
InChI:
InChI=1S/C7H8N2O2/c1-8-7(11)5-2-3-6(10)9-4-5/h2-4H,1H3,(H,8,11)(H,9,10)
InChI Key:
NBUNJDAKVMXXEF-UHFFFAOYSA-N
SMILES:
CNC(=O)c1ccc(=O)[nH]c1
UNII:
C2M49S613F
Properties
Complexity:
253
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
1
Defined Atom Stereocenter Count:
0
Defined Bond Stereocenter Count:
0
Exact Mass:
152.059g/mol
Formal Charge:
0
Heavy Atom Count:
11
Hydrogen Bond Acceptor Count:
2
Hydrogen Bond Donor Count:
2
Isotope Atom Count:
0
Molecular Weight:
152.153g/mol
Monoisotopic Mass:
152.059g/mol
Rotatable Bond Count:
1
Topological Polar Surface Area:
58.2A^2
Undefined Atom Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
XLogP3:
-0.8
Literature
| Title | Journal |
|---|---|
| N-Methyl-2-pyridone-5-carboxamide is 1-methylnicotinamide metabolite of low cyclooxygenase-dependent vasodilating activity. | Journal of physiology and biochemistry 20120901 |
| Simultaneous quantification of niacin and its three main metabolites in human plasma by LC-MS/MS. | Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20120901 |
| Effects of 1-methylnicotinamide and its metabolite N-methyl-2-pyridone-5-carboxamide on streptozotocin-induced toxicity in murine insulinoma MIN6 cell line. | Acta biochimica Polonica 20110101 |
| Simultaneous determination of niacin and its metabolites--nicotinamide, nicotinuric acid and N-methyl-2-pyridone-5-carboxamide--in human plasma by LC-MS/MS and its application to a human pharmacokinetic study. | Biomedical chromatography : BMC 20101001 |
| Distribution of purine nucleotides in uremic fluids and tissues. | Journal of renal nutrition : the official journal of the Council on Renal Nutrition of the National Kidney Foundation 20100901 |
| Urinary metabolic phenotyping differentiates children with autism from their unaffected siblings and age-matched controls. | Journal of proteome research 20100604 |
| Metabonomics study of urine and plasma in depression and excess fatigue rats by ultra fast liquid chromatography coupled with ion trap-time of flight mass spectrometry. | Molecular bioSystems 20100501 |
| Development of a hydrophilic liquid interaction chromatography-high-performance liquid chromatography-tandem mass spectrometry based stable isotope dilution analysis and pharmacokinetic studies on bioactive pyridines in human plasma and urine after coffee consumption. | Analytical chemistry 20100215 |
| Are so-called uremic toxins always toxic? | Journal of renal nutrition : the official journal of the Council on Renal Nutrition of the National Kidney Foundation 20080101 |
| Nicotinamide metabolites accumulate in the tissues of uremic rats. | Journal of renal nutrition : the official journal of the Council on Renal Nutrition of the National Kidney Foundation 20080101 |
| The comparative bioavailability of an extended-release niacin and lovastatin fixed dose combination tablet versus extended-release niacin tablet, lovastatin tablet and a combination of extended-release niacin tablet and lovastatin tablet. | Biopharmaceutics & drug disposition 20070901 |
| Plasma and urine pharmacokinetics of niacin and its metabolites from an extended-release niacin formulation. | International journal of clinical pharmacology and therapeutics 20070801 |
| Effect of the rate of niacin administration on the plasma and urine pharmacokinetics of niacin and its metabolites. | Journal of clinical pharmacology 20070601 |
| A metabolomic comparison of urinary changes in type 2 diabetes in mouse, rat, and human. | Physiological genomics 20070424 |
| Relationship between uremic toxins and oxidative stress in patients with chronic renal failure. | Scandinavian journal of urology and nephrology 20070101 |
| Accumulation of poly(ADP-ribose) polymerase inhibitors in children with chronic renal failure. | Pediatric nephrology (Berlin, Germany) 20060601 |
| Estimation of aldehyde oxidase activity in vivo from conversion ratio of N1-methylnicotinamide to pyridones, and intraspecies variation of the enzyme activity in rats. | Drug metabolism and disposition: the biological fate of chemicals 20060201 |
| The novel nucleotide 4KNTP, in high concentrations in erythrocytes of renal failure children: a comparison with accumulation of other putative precursors in the plasma. | Nucleosides, nucleotides & nucleic acids 20060101 |
| The effect of N-methyl-2-pyridone-5-carboxamide--A nicotinamide catabolite on poly ADP-rybosylation and oxidative stress injury in endothelial cells. | Nucleosides, nucleotides & nucleic acids 20050101 |
| The age-related increase in N-methyl-2-pyridone-5-carboxamide (NAD catabolite) in human plasma. | Molecular and cellular biochemistry 20041201 |
| An unusual pyridine nucleotide accumulating in erythrocytes: its identity and positive correlation with degree of renal failure. | Nucleosides, nucleotides & nucleic acids 20041001 |
| Disturbances of purine nucleotide metabolism in uremia. | Seminars in nephrology 20040901 |
| Origin and characteristics of an unusual pyridine nucleotide accumulating in erythrocytes: positive correlation with degree of renal failure. | Clinica chimica acta; international journal of clinical chemistry 20030901 |
| N-methyl-2-pyridone-5-carboxamide: a novel uremic toxin? | Kidney international. Supplement 20030501 |
| Accumulation of plasma N-methyl-2-pyridone-5-carboxamide in patients with chronic renal failure. | Molecular and cellular biochemistry 20020201 |
| The metabolism of nicotinamide in human liver cirrhosis: a study on N-methylnicotinamide and 2-pyridone-5-carboxamide production. | The American journal of gastroenterology 20010401 |
Related Products
Featured Products
© 2019 Angene International Limited. All rights Reserved.