200,000+ products from a single source!
sales@angenechem.com
1005-24-9 | Pyridinium, 3-(aminocarbonyl)-1-methyl-, chloride (1:1)
CAS No: 1005-24-9 Catalog No: AG00025R MDL No:MFCD00060042
Product Description
Catalog Number:
AG00025R
Chemical Name:
Pyridinium, 3-(aminocarbonyl)-1-methyl-, chloride (1:1)
CAS Number:
1005-24-9
Molecular Formula:
C7H9ClN2O
Molecular Weight:
172.6122
MDL Number:
MFCD00060042
IUPAC Name:
1-methylpyridin-1-ium-3-carboxamide;chloride
InChI:
InChI=1S/C7H8N2O.ClH/c1-9-4-2-3-6(5-9)7(8)10;/h2-5H,1H3,(H-,8,10);1H
InChI Key:
BWVDQVQUNNBTLK-UHFFFAOYSA-N
SMILES:
C[n+]1cccc(c1)C(=O)N.[Cl-]
EC Number:
463-670-7
UNII:
L54XNJ1D5G
Properties
Complexity:
136
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
2
Defined Atom Stereocenter Count:
0
Defined Bond Stereocenter Count:
0
Exact Mass:
172.04g/mol
Formal Charge:
0
Heavy Atom Count:
11
Hydrogen Bond Acceptor Count:
2
Hydrogen Bond Donor Count:
1
Isotope Atom Count:
0
Molecular Weight:
172.612g/mol
Monoisotopic Mass:
172.04g/mol
Rotatable Bond Count:
1
Topological Polar Surface Area:
47A^2
Undefined Atom Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
Literature
| Title | Journal |
|---|---|
| N-Methyl-2-pyridone-5-carboxamide is 1-methylnicotinamide metabolite of low cyclooxygenase-dependent vasodilating activity. | Journal of physiology and biochemistry 20120901 |
| Toxic effects of nicotinamide methylation on mouse brain striatum neuronal cells and its relation to manganese. | Environmental health and preventive medicine 20120901 |
| Excess nicotinamide inhibits methylation-mediated degradation of catecholamines in normotensives and hypertensives. | Hypertension research : official journal of the Japanese Society of Hypertension 20120201 |
| Effects of N1-methylnicotinamide on oxidative and glycooxidative stress markers in rats with streptozotocin-induced diabetes mellitus. | Redox report : communications in free radical research 20120101 |
| Developmental changes of aldehyde oxidase activity and protein expression in human liver cytosol. | Drug metabolism and pharmacokinetics 20120101 |
| Decreased skin-mediated detoxification contributes to oxidative stress and insulin resistance. | Experimental diabetes research 20120101 |
| The expression of nicotinamide N-methyltransferase increases ATP synthesis and protects SH-SY5Y neuroblastoma cells against the toxicity of Complex I inhibitors. | The Biochemical journal 20110515 |
| ¹H nuclear magnetic resonance based metabolic urinary profiling of patients with ischemic heart failure. | Clinical biochemistry 20110301 |
| Effect of tea beverages on aldehyde oxidase activity. | Drug metabolism and pharmacokinetics 20110101 |
| Effects of 1-methylnicotinamide and its metabolite N-methyl-2-pyridone-5-carboxamide on streptozotocin-induced toxicity in murine insulinoma MIN6 cell line. | Acta biochimica Polonica 20110101 |
| Effect of selected NAD+ analogues on mitochondria activity and proliferation of endothelial EA.hy926 cells. | European journal of pharmacology 20100825 |
| 1-methylnicotinamide effects on the selected markers of endothelial function, inflammation and haemostasis in diabetic rats. | European journal of pharmacology 20100825 |
| 3-D-QSAR and docking studies on the neuronal choline transporter. | Bioorganic & medicinal chemistry letters 20100815 |
| [Effect of 1-methylnicotinamide on prooxidant-antioxidant balance parameters in rats during hepatic ischemia-reperfusion]. | Eksperimental'naia i klinicheskaia farmakologiia 20100401 |
| 1-methylnicotinamide (MNA) in prevention of diabetes-associated brain disorders. | Neurochemistry international 20100101 |
| Nicotinamide N-methyltransferase (NNMT) and 1-methylnicotinamide (MNA) in experimental hepatitis induced by concanavalin A in the mouse. | Pharmacological reports : PR 20100101 |
| Effect of nicotinamide and its two derivatives on the generation of reactive oxygen species in human monocytes cooperating with platelets. | Acta poloniae pharmaceutica 20100101 |
| Nicotinamide overload may play a role in the development of type 2 diabetes. | World journal of gastroenterology 20091207 |
| Adipose tissue as a source of nicotinamide N-methyltransferase and homocysteine. | Atherosclerosis 20090601 |
| Activation of nicotinamide N-methyltrasferase and increased formation of 1-methylnicotinamide (MNA) in atherosclerosis. | Pharmacological reports : PR 20090101 |
| Anti-diabetic effects of 1-methylnicotinamide (MNA) in streptozocin-induced diabetes in rats. | Pharmacological reports : PR 20090101 |
| Matrix metaloproteinases activity during the evolution of hypoxic-ischemic brain damage in the immature rat. The effect of 1-methylnicotinamide (MNA). | Journal of physiology and pharmacology : an official journal of the Polish Physiological Society 20080901 |
| Aldehyde oxidase-catalyzed metabolism of N1-methylnicotinamide in vivo and in vitro in chimeric mice with humanized liver. | Drug metabolism and disposition: the biological fate of chemicals 20080701 |
| Therapeutic potential of 1-methylnicotinamide against acute gastric lesions induced by stress: role of endogenous prostacyclin and sensory nerves. | The Journal of pharmacology and experimental therapeutics 20080701 |
| 1-Methylnicotinamide and nicotinamide: two related anti-inflammatory agents that differentially affect the functions of activated macrophages. | Archivum immunologiae et therapiae experimentalis 20080401 |
| Anti-inflammatory effect of 1-methylnicotinamide in contact hypersensitivity to oxazolone in mice; involvement of prostacyclin. | European journal of pharmacology 20080114 |
| 1-Methylnicotinamide (MNA) prevents endothelial dysfunction in hypertriglyceridemic and diabetic rats. | Pharmacological reports : PR 20080101 |
| Neuroprotective effects of nicotinamide and 1-methylnicotinamide in acute excitotoxicity in vitro. | Folia neuropathologica 20080101 |
| Nicotinamide and 1-methylnicotinamide reduce homocysteine neurotoxicity in primary cultures of rat cerebellar granule cells. | Acta neurobiologiae experimentalis 20080101 |
| 1-Methylnicotinamide stimulates cell growth and inhibits hemoglobin synthesis in differentiating murine erythroleukemia cells. | Toxicology in vitro : an international journal published in association with BIBRA 20071201 |
| 1-Methylnicotinamide (MNA), a primary metabolite of nicotinamide, exerts anti-thrombotic activity mediated by a cyclooxygenase-2/prostacyclin pathway. | British journal of pharmacology 20070901 |
| Developmental changes of aldehyde oxidase in postnatal rat liver. | Drug metabolism and pharmacokinetics 20070401 |
| Metabolites of the radiosensitizer nicotinamide are unlikely to contribute to the degree of emesis observed with the parent drug. | Oncology research 20070101 |
| Spectrofluorimetric determination of drugs containing active methylene group using N1-methyl nicotinamide chloride as a fluorigenic agent. | Chemical & pharmaceutical bulletin 20060701 |
| Estimation of aldehyde oxidase activity in vivo from conversion ratio of N1-methylnicotinamide to pyridones, and intraspecies variation of the enzyme activity in rats. | Drug metabolism and disposition: the biological fate of chemicals 20060201 |
| Search for drugs of the combined anti-inflammatory and anti-bacterial properties: 1-methyl-N'-(hydroxymethyl)nicotinamide. | Pharmacological reports : PR 20060101 |
| [The effect of magnesium pool isotopy on reactivation of mitochondrial ATP synthesis suppressed by 1-methyl-nicotine amide]. | Biomeditsinskaia khimiia 20060101 |
| Topical application of 1-methylnicotinamide in the treatment of rosacea: a pilot study. | Clinical and experimental dermatology 20051101 |
| Quantitation of the niacin metabolites 1-methylnicotinamide and l-methyl-2-pyridone-5-carboxamide in random spot urine samples, by ion-pairing reverse-phase HPLC with UV detection, and the implications for the use of spot urine samples in the assessment of niacin status. | Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20050325 |
| Spectrofluorimetric determination of warfarin sodium by using N1-methylnicotinamide chloride as a fluorigenic agent. | Journal of AOAC International 20050101 |
| 1-Methylnicotinamide: a potent anti-inflammatory agent of vitamin origin. | Polish journal of pharmacology 20030101 |
| Potential urinary and plasma biomarkers of peroxisome proliferation in the rat: identification of N-methylnicotinamide and N-methyl-4-pyridone-3-carboxamide by 1H nuclear magnetic resonance and high performance liquid chromatography. | Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals 20030101 |
| [Elucidation of paraquat poisoning mechanism and development of the neuronal death model]. | Nihon eiseigaku zasshi. Japanese journal of hygiene 20020401 |
| Possible role of 1-methylnicotinamide in the pathogenesis of Parkinson's disease. | Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie 20020201 |
| Rapid calmodulin-dependent interdomain electron transfer in neuronal nitric-oxide synthase measured by pulse radiolysis. | The Journal of biological chemistry 20011026 |
| Validation of an HPLC method for the determination of urinary and plasma levels of N1-methylnicotinamide, an endogenous marker of renal cationic transport and plasma flow. | Journal of pharmaceutical and biomedical analysis 20010101 |
Related Products
Featured Products
© 2019 Angene International Limited. All rights Reserved.