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100-88-9

100-88-9 | Sulfamic acid, N-cyclohexyl-

CAS No: 100-88-9 Catalog No: AG00007S MDL No:MFCD00065234

Product Description

Catalog Number:
AG00007S
Chemical Name:
Sulfamic acid, N-cyclohexyl-
CAS Number:
100-88-9
Molecular Formula:
C6H13NO3S
Molecular Weight:
179.2373
MDL Number:
MFCD00065234
IUPAC Name:
cyclohexylsulfamic acid
InChI:
InChI=1S/C6H13NO3S/c8-11(9,10)7-6-4-2-1-3-5-6/h6-7H,1-5H2,(H,8,9,10)
InChI Key:
HCAJEUSONLESMK-UHFFFAOYSA-N
SMILES:
OS(=O)(=O)NC1CCCCC1
EC Number:
202-898-1
UNII:
HN3OFO5036

Properties

Complexity:
200  
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
0
Defined Bond Stereocenter Count:
0
Exact Mass:
179.062g/mol
Formal Charge:
0
Heavy Atom Count:
11  
Hydrogen Bond Acceptor Count:
4  
Hydrogen Bond Donor Count:
2  
Isotope Atom Count:
0
Molecular Weight:
179.234g/mol
Monoisotopic Mass:
179.062g/mol
Rotatable Bond Count:
2  
Topological Polar Surface Area:
74.8A^2
Undefined Atom Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
XLogP3:
0.6  

Literature

Title Journal
Application of dispersive solid-phase extraction and ultra-fast liquid chromatography-tandem quadrupole mass spectrometry in food additive residue analysis of red wine. Journal of chromatography. A 20121109
Functional characterization of the heterodimeric sweet taste receptor T1R2 and T1R3 from a New World monkey species (squirrel monkey) and its response to sweet-tasting proteins. Biochemical and biophysical research communications 20121019
Determination of artificial sweeteners in water samples by solid-phase extraction and liquid chromatography-tandem mass spectrometry. Journal of chromatography. A 20120921
Improvement of physicochemical properties of an antiepileptic drug by salt engineering. AAPS PharmSciTech 20120901
Stability considerations of aspartame in the direct analysis of artificial sweeteners in water samples using high-performance liquid chromatography-tandem mass spectrometry (HPLC-MS/MS). Chemosphere 20120701
Artificial sweeteners--a recently recognized class of emerging environmental contaminants: a review. Analytical and bioanalytical chemistry 20120701
Anticonvulsant activity of artificial sweeteners: a structural link between sweet-taste receptor T1R3 and brain glutamate receptors. Bioorganic & medicinal chemistry letters 20120615
Structural elucidation of main ozonation products of the artificial sweeteners cyclamate and acesulfame. Environmental science and pollution research international 20120501
Homogeneous CO2 reduction by Ni(cyclam) at a glassy carbon electrode. Inorganic chemistry 20120402
Reduction of CO2 to CO at low overpotential in neutral aqueous solution by a Ni(cyclam) complex attached to poly(allylamine). ChemSusChem 20120401
Qualitative and quantitative control of carbonated cola beverages using ¹H NMR spectroscopy. Journal of agricultural and food chemistry 20120321
[Determination of sodium cyclamate in liquor by high performance liquid chromatography-tandem mass spectrometry with linear trap technology]. Se pu = Chinese journal of chromatography 20120301
[Simultaneous determination of five synthetic sweeteners in food by solid phase extraction-high performance liquid chromatography-evaporative light scattering detection]. Se pu = Chinese journal of chromatography 20120301
Radiolabelled peptides for oncological diagnosis. European journal of nuclear medicine and molecular imaging 20120201
Oviposition and Embryotoxicity of Indigofera suffruticosa on Early Development of Aedes aegypti (Diptera: Culicidae). Evidence-based complementary and alternative medicine : eCAM 20120101
Dietary intake of artificial sweeteners by the Belgian population. Food additives & contaminants. Part A, Chemistry, analysis, control, exposure & risk assessment 20120101
Identification of anti-malarial compounds as novel antagonists to chemokine receptor CXCR4 in pancreatic cancer cells. PloS one 20120101
Characterization of the modes of binding between human sweet taste receptor and low-molecular-weight sweet compounds. PloS one 20120101
Differential Expression of Chemokine Receptors and their Roles in Cancer Imaging. Frontiers in oncology 20120101
Stroma targeting nuclear imaging and radiopharmaceuticals. International journal of molecular imaging 20120101
The content of high-intensity sweeteners in different categories of foods available on the Polish market. Food additives & contaminants. Part A, Chemistry, analysis, control, exposure & risk assessment 20120101
The Role of the Sweet Taste Receptor in Enteroendocrine Cells and Pancreatic β-Cells. Diabetes & metabolism journal 20111001
Relationships among taste qualities assessed with response-context effects. Chemical senses 20110901
New iron(III) bis(acetylide) compounds based on the iron cyclam motif. Inorganic chemistry 20110815
Di-μ-oxido-bis-[(1,4,8,11-tetra-aza-cyclo-tetra-decane-κN,N',N'',N''')dimangan-ese(III,IV)] bis-(tetra-phenyl-borate) chloride acetonitrile disolvate. Acta crystallographica. Section E, Structure reports online 20110701
Determination of nine high-intensity sweeteners in various foods by high-performance liquid chromatography with mass spectrometric detection. Analytical and bioanalytical chemistry 20110601
Imaging CXCR4 expression in human cancer xenografts: evaluation of monocyclam 64Cu-AMD3465. Journal of nuclear medicine : official publication, Society of Nuclear Medicine 20110601
Determination of artificial sweeteners in beverages and special nutritional products using high performance liquid chromatography. Arhiv za higijenu rada i toksikologiju 20110601
[Determination of three sweeteners in vinegars by solid phase extraction-high performance liquid chromatography/tandem mass spectrometry]. Se pu = Chinese journal of chromatography 20110601
Nonnutritive sweeteners, fructose, and other aspects of diet. Diabetes care 20110501
[Use of diet sweeteners by adults in Pelotas, Rio Grande do Sul State, Brazil: a population-based study]. Cadernos de saude publica 20110501
Electron exchange columns through entrapment of a nickel cyclam in a sol-gel matrix. Chemistry (Weinheim an der Bergstrasse, Germany) 20110426
[Study on optimization of formulation of Danggui Liuhuang effervescent granules]. Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials 20110301
Importance of receptor flexibility in binding of cyclam compounds to the chemokine receptor CXCR4. Journal of chemical information and modeling 20110124
Saccharin and other artificial sweeteners in soils: estimated inputs from agriculture and households, degradation, and leaching to groundwater. Environmental science & technology 20110115
Olfactory sensitivity for sperm-attractant aromatic aldehydes: a comparative study in human subjects and spider monkeys. Journal of comparative physiology. A, Neuroethology, sensory, neural, and behavioral physiology 20110101
Polyamide-scorpion cyclam lexitropsins selectively bind AT-rich DNA independently of the nature of the coordinated metal. PloS one 20110101
A systematic review on the effect of sweeteners on glycemic response and clinically relevant outcomes. BMC medicine 20110101
Biological Significance of GPCR Heteromerization in the Neuro-Endocrine System. Frontiers in endocrinology 20110101
Effects of artificial sweeteners on body weight, food and drink intake. Acta physiologica Hungarica 20101201
[Simultaneous determination of six synthetic sweeteners in food by high performance liquid chromatography-tandem mass spectrometry]. Se pu = Chinese journal of chromatography 20101101
Retention behaviour of some high-intensity sweeteners on different SPE sorbents. Talanta 20101015
Novel monocyclam derivatives as HIV entry inhibitors: Design, synthesis, anti-HIV evaluation, and their interaction with the CXCR4 co-receptor. ChemMedChem 20100802
Sensory quality of functional beverages: bitterness perception and bitter masking of olive leaf extract fortified fruit smoothies. Journal of food science 20100801
[Determination of five synthetic sweeteners in wines using high performance liquid chromatography-tandem mass spectrometry]. Se pu = Chinese journal of chromatography 20100801
Responses of single chorda tympani taste fibers of the calf (Bos taurus). Chemical senses 20100601
Stevia and saccharin preferences in rats and mice. Chemical senses 20100601
Performance of conventional multi-barrier drinking water treatment plants for the removal of four artificial sweeteners. Water research 20100601
Gain weight by 'going diet?' Artificial sweeteners and the neurobiology of sugar cravings: Neuroscience 2010. The Yale journal of biology and medicine 20100601
Key amino acid residues involved in multi-point binding interactions between brazzein, a sweet protein, and the T1R2-T1R3 human sweet receptor. Journal of molecular biology 20100514
Positive allosteric modulators of the human sweet taste receptor enhance sweet taste. Proceedings of the National Academy of Sciences of the United States of America 20100309
Artificial sweetener as a historical window to culturally situated health. Annals of the New York Academy of Sciences 20100301
Tailored adsorption of His6-tagged protein onto nickel(II)-cyclam grafted mesoporous silica. Chemical communications (Cambridge, England) 20100221
Oxovanadium(IV) cyclam and bicyclam complexes: potential CXCR4 receptor antagonists. Inorganic chemistry 20100201
An attempt to use sweeteners as a material for accident dosimetry. Health physics 20100201
Anionic leak currents through the Na+/monocarboxylate cotransporter SMCT1. American journal of physiology. Cell physiology 20100101
Sugar alcohols, caries incidence, and remineralization of caries lesions: a literature review. International journal of dentistry 20100101
Chronic consumption of fructose rich soft drinks alters tissue lipids of rats. Diabetology & metabolic syndrome 20100101
Evaluation of certain food additives. Seventy-first report of the Joint FAO/WHO Expert Committee on Food Additives. World Health Organization technical report series 20100101
Analysis and occurrence of seven artificial sweeteners in German waste water and surface water and in soil aquifer treatment (SAT). Analytical and bioanalytical chemistry 20090701
Food additives and sensitivities. Disease-a-month : DM 20090501
Development and single-laboratory validation of an HPLC method for the determination of cyclamate sweetener in foodstuffs. Food additives & contaminants. Part A, Chemistry, analysis, control, exposure & risk assessment 20090501
Simultaneous determination of nonnutritive sweeteners in foods by HPLC/ESI-MS. Journal of agricultural and food chemistry 20090422
Magnetic behaviour of nickel-cyclam complexes in mesoporous silica: EPR investigations. Journal of physics. Condensed matter : an Institute of Physics journal 20090218
Soft fruit traceability in food matrices using real-time PCR. Nutrients 20090201
Sweet taste receptor expressed in pancreatic beta-cells activates the calcium and cyclic AMP signaling systems and stimulates insulin secretion. PloS one 20090101
Determination of nine intense sweeteners in foodstuffs by high-performance liquid chromatography and evaporative light-scattering detection: interlaboratory study. Journal of AOAC International 20090101
A phase II study on safety and efficacy of high-dose N-acetylcysteine in patients with cystic fibrosis. European journal of medical research 20090101
Genetic and molecular basis of individual differences in human umami taste perception. PloS one 20090101
Zolpidem, a clinical hypnotic that affects electronic transfer, alters synaptic activity through potential GABA receptors in the nervous system without significant free radical generation. Oxidative medicine and cellular longevity 20090101
Development of membrane selective electrode for determination of the antipsychotic sulpiride in pharmaceuticals and urine. Sensors (Basel, Switzerland) 20090101
Asymmetric organocatalytic Michael addition of ketones to vinyl sulfone. Chemical communications (Cambridge, England) 20081221
The capsaicin receptor participates in artificial sweetener aversion. Biochemical and biophysical research communications 20081128
Simultaneous square-wave voltammetric determination of aspartame and cyclamate using a boron-doped diamond electrode. Talanta 20080730
Catalyzed oxidative corrosion of porous silicon used as an optical transducer for ligand-receptor interactions. Chembiochem : a European journal of chemical biology 20080721
Artificial sweetener consumption and urinary tract tumors in Cordoba, Argentina. Preventive medicine 20080701
[Compound preservative and cyclamat determinated by gas chromatography]. Wei sheng yan jiu = Journal of hygiene research 20080701
Direct NMR detection of the binding of functional ligands to the human sweet receptor, a heterodimeric family 3 GPCR. Journal of the American Chemical Society 20080611
Estimated intake of intense sweeteners from non-alcoholic beverages in Denmark, 2005. Food additives & contaminants. Part A, Chemistry, analysis, control, exposure & risk assessment 20080601
Chemical carcinogenesis studies in nonhuman primates. Proceedings of the Japan Academy. Series B, Physical and biological sciences 20080601
Determination by high-frequency and -field EPR of zero-field splitting in iron(IV) oxo complexes: implications for intermediates in nonheme iron enzymes. Inorganic chemistry 20080505
Spanish Ketogenic Mediterranean Diet: a healthy cardiovascular diet for weight loss. Nutrition journal 20080101
Determination of cyclamate in foods by ultraperformance liquid chromatography/tandem mass spectrometry. Journal of AOAC International 20080101
Synthesis, characterization and antimycobacterial activity of Ag(I)-aspartame, Ag(I)-saccharin and Ag(I)-cyclamate complexes. Archiv der Pharmazie 20071001
Influence of artificial sweeteners on the kinetic and metabolic behavior of Lactobacillus delbrueckii subsp. bulgaricus. Journal of food protection 20071001
Molecular mechanism of action of monocyclam versus bicyclam non-peptide antagonists in the CXCR4 chemokine receptor. The Journal of biological chemistry 20070914
Life-span exposure to low doses of aspartame beginning during prenatal life increases cancer effects in rats. Environmental health perspectives 20070901
Artificial sweeteners and salts producing a metallic taste sensation activate TRPV1 receptors. American journal of physiology. Regulatory, integrative and comparative physiology 20070801
Simultaneous determination of nine intense sweeteners in foodstuffs by high performance liquid chromatography and evaporative light scattering detection--development and single-laboratory validation. Journal of chromatography. A 20070720
Rapid determination of cyclamate in foods by solid-phase extraction and capillary electrophoresis. Journal of chromatography. A 20070622
Structures of artificial sweeteners--cyclamic acid and sodium cyclamate with other cyclamates. Acta crystallographica. Section B, Structural science 20070601
[Restless legs due to ingestion of 'light' beverages containing saccharine. Results of an N-of-1 trial]. Nederlands tijdschrift voor tandheelkunde 20070601
A conductive pathway generated from fragments of the human red cell anion exchanger AE1. The Journal of physiology 20070515
Copper(II) cyclam-based complexes for radiopharmaceutical applications: synthesis and structural analysis. Dalton transactions (Cambridge, England : 2003) 20070307
Estimated intake of intense sweeteners from non-alcoholic beverages in Denmark. Food additives and contaminants 20070301
Riboflavin-binding protein exhibits selective sweet suppression toward protein sweeteners. Chemical senses 20070201
Configurations of nickel-cyclam antiviral complexes and protein recognition. Chemistry (Weinheim an der Bergstrasse, Germany) 20070101
Exceptional affinity of nanostructured organic-inorganic hybrid materials towards dioxygen: confinement effect of copper complexes. Chemistry (Weinheim an der Bergstrasse, Germany) 20070101
The binding site for neohesperidin dihydrochalcone at the human sweet taste receptor. BMC structural biology 20070101
Influence of artificial sweetener on human blood glucose concentration. TheScientificWorldJournal 20070101
[Restless legs due to ingestion of 'light' beverages containing saccharine; results of an N-of-1 trial]. Nederlands tijdschrift voor geneeskunde 20061223
Development of a new oat-based probiotic drink. International journal of food microbiology 20061015
[Optimization of preparative technique for banxia-houpu effervescent tablets by orthogonal design]. Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials 20061001
Swelling-activated Cl- channels support Cl- secretion by bovine ciliary epithelium. Investigative ophthalmology & visual science 20060601
The G protein-coupled receptor subset of the chicken genome. PLoS computational biology 20060601
Mechanism of iodide transport in the rabbit cortical collecting duct. Clinical and experimental nephrology 20060601
Direct simultaneous determination of eight sweeteners in foods by capillary isotachophoresis. Journal of separation science 20060501
High-performance liquid chromatography-electronspray ionization mass spectrometry for determination of tiopronin in human plasma. Journal of chromatography. A 20060428
The intake of intense sweeteners - an update review. Food additives and contaminants 20060401
First experimental demonstration of the multipotential carcinogenic effects of aspartame administered in the feed to Sprague-Dawley rats. Environmental health perspectives 20060301
Fluorescent nanoparticles as selective Cu(II) sensors. Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology 20060301
The heterodimeric sweet taste receptor has multiple potential ligand binding sites. Current pharmaceutical design 20060101
Bitterness suppression with zinc sulfate and na-cyclamate: a model of combined peripheral and central neural approaches to flavor modification. Pharmaceutical research 20051101
Identification of the cyclamate interaction site within the transmembrane domain of the human sweet taste receptor subunit T1R3. The Journal of biological chemistry 20051007
Separation and simultaneous determination of four artificial sweeteners in food and beverages by ion chromatography. Journal of chromatography. A 20050826
Synthesis and complexation of 'back-to-back' capped bis-dioxocyclams. Inorganic chemistry 20050808
Metal-containing trifurcate receptor that recognizes and senses citrate in water. Organic letters 20050623
[Analysis of nine kinds of sweeteners in foods by LC/MS]. Shokuhin eiseigaku zasshi. Journal of the Food Hygienic Society of Japan 20050601
Catabolism of sulfamate by Mycobacterium sp. CF1. Environmental microbiology 20050301
Sweet proteins--potential replacement for artificial low calorie sweeteners. Nutrition journal 20050101
Taste modulators are tools to gain a better insight into specific sensitivity of chemoreceptors in blowflies. Chemical senses 20050101
Valine 738 and lysine 735 in the fifth transmembrane domain of rTas1r3 mediate insensitivity towards lactisole of the rat sweet taste receptor. BMC neuroscience 20050101
Artificial sweeteners--do they bear a carcinogenic risk? Annals of oncology : official journal of the European Society for Medical Oncology 20041001
Different functional roles of T1R subunits in the heteromeric taste receptors. Proceedings of the National Academy of Sciences of the United States of America 20040928
Oral zinc sulfate solutions inhibit sweet taste perception. Chemical senses 20040701
The metabolism of cyclamate to cyclohexylamine in humans during long-term administration. Toxicology and applied pharmacology 20040501
Flow-injection determination of amine contaminants in cyclamate samples based on temperature for controlling selectivity. The Analyst 20040501
Three-ring, branched cyclam derivatives and their interaction with nickel(II), copper(II), zinc(II) and cadmium(II). Dalton transactions (Cambridge, England : 2003) 20040421
Receptors for bitter, sweet and umami taste couple to inhibitory G protein signaling pathways. European journal of pharmacology 20040412
Dietary estimated intake of intense sweeteners by Italian teenagers. Present levels and projections derived from the INRAN-RM-2001 food survey. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20040401
Behavioral study in the gray mouse lemur (Microcebus murinus) using compounds considered sweet by humans. American journal of primatology 20040101
Cyclamate intake and cyclohexylamine excretion are not related to male fertility in humans. Food additives and contaminants 20031201
Selective recognition of configurational substates of zinc cyclam by carboxylates: implications for the design and mechanism of action of anti-HIV agents. Chemistry (Weinheim an der Bergstrasse, Germany) 20031006
Probabilistic modelling of human exposure to intense sweeteners in Italian teenagers: validation and sensitivity analysis of a probabilistic model including indicators of market share and brand loyalty. Food additives and contaminants 20031001
Synthesis, complexation, and coordination oligomerization of 1,8-pyrazine-capped 5,12-dioxocyclams. Inorganic chemistry 20030714
Effects of a saccharin and cyclamate mixture on rat embryos. Veterinary and human toxicology 20030601
Is the negative charge on RNHSO3-M+ an essential requirement for sulfamate sweetness? Journal of agricultural and food chemistry 20030507
Blockade of peroxynitrite-mediated astrocyte death by manganese(III)-cyclam. Neuroscience research 20030201
Estimated intake of the artificial sweeteners acesulfame-K, aspartame, cyclamate and saccharin in a group of Swedish diabetics. Food additives and contaminants 20030201
[Controversies with aspartame]. Medicinski pregled 20030101
Octahedral (cis-cyclam)iron(III) complexes with O,N-coordinated o-iminosemiquinonate(1-) pi radicals and o-imidophenolate(2-) anions. Inorganic chemistry 20021007
The comet assay with 8 mouse organs: results with 39 currently used food additives. Mutation research 20020826
Cadmium cyclam complexes: interconversion of cis and trans configurations and fixation of CO(2). Inorganic chemistry 20020826
Application of the U and gamma' models in binary sweet taste mixtures. Chemical senses 20020701
Aspartame optical biosensor with bienzyme-immobilized eggshell membrane and oxygen-sensitive optode membrane. Analytical chemistry 20020215
[Infrared spectroscopy of the dry residue of liquor crystallograms in various diseases]. Sudebno-meditsinskaia ekspertiza 20020101
Selective continuous monitoring and analysis of mixtures of acesulfame-K, cyclamate, and saccharin in artificial sweetener tablets, diet soft drinks, yogurts, and wines using filter-supported bilayer lipid membranes. Analytical chemistry 20011215
[Artificial sweeteners--are they potentially carcinogenic?]. Medizinische Klinik (Munich, Germany : 1983) 20011115
Sweetener preference of C57BL/6ByJ and 129P3/J mice. Chemical senses 20010901
Liposome aggregation in presence of the sweeteners cyclamate and saccharine. Die Pharmazie 20010801
[Simultaneous determination of various food additives by high performance liquid chromatography]. Se pu = Chinese journal of chromatography 20010301
Inhalation toxicity studies of the alpha,beta-unsaturated ketones: 2-cyclohexene-1-one. Inhalation toxicology 20010101
Improved water solubility of neohesperidin dihydrochalcone in sweetener blends. Journal of agricultural and food chemistry 20010101
pH changes in dental plaque after using sugar-free pediatric medicine. The Journal of clinical pediatric dentistry 20010101
Effects of treatment with N-methyl-N-nitrosourea, artificial sweeteners, and cyclophosphamide on adult rat urinary bladder in vitro. Laboratory investigation; a journal of technical methods and pathology 19871001
Effect of partial cystectomy on the induction of pre-neoplastic lesions in rat bladder initiated with N-butyl-N-(4-hydroxybutyl)nitrosamine followed by bladder carcinogens and promoters. Urological research 19820101
Purification and some properties of cyclohexylamine oxidase from a Pseudomonas sp. Journal of biochemistry 19770401
Partial purification and some properties of cyclamate sulfamatase. Journal of biochemistry 19740201

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