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CAS No: 100-76-5 Catalog No: AG00006Q MDL No:MFCD00006690
|Excited-state proton transfer and ion pair formation in a Cinchona organocatalyst.
|Physical chemistry chemical physics : PCCP 20121005
|Boron nitride nanotubes and their functionalization via quinuclidine-3-thiol with gold nanoparticles for the development and enhancement of the HPLC performance of HPLC monolithic columns.
|Design and synthesis of novel opioid ligands with an azabicyclo[2.2.2]octane skeleton and their pharmacologies.
|Bioorganic & medicinal chemistry letters 20120415
|Scope of stereoselective Mn-mediated radical addition to chiral hydrazones and application in a formal synthesis of quinine.
|The Journal of organic chemistry 20120406
|Asymmetric total synthesis of (+)-virosine A via sequential nucleophilic cyclizations onto an activated formamide.
|The Journal of organic chemistry 20120406
|Making SharePoint® Chemically Aware™.
|Journal of cheminformatics 20120101
|Scopolamine administration modulates muscarinic, nicotinic and NMDA receptor systems.
|PloS one 20120101
|The role of neurokinin-1 receptor in the microenvironment of inflammation and cancer.
|Reactions of nitroxides XIII: Synthesis of the Morita-Baylis-Hillman adducts bearing a nitroxyl moiety using 4-acryloyloxy-2,2,6,6-tetramethylpiperidine-1-oxyl as a starting compound, and DABCO and quinuclidine as catalysts.
|Beilstein journal of organic chemistry 20120101
|Stepwise effective molarities in porphyrin oligomer complexes: preorganization results in exceptionally strong chelate cooperativity.
|Journal of the American Chemical Society 20111228
|Asymmetric hydrogenation on chirally modified Pt: origin of hydrogen in the N-H-O interaction between cinchonidine and ketone.
|Journal of the American Chemical Society 20111214
|New spirocyclic Δ²-isoxazoline derivatives related to selective agonists of α7 neuronal nicotinic acetylcholine receptors.
|European journal of medicinal chemistry 20111201
|Diastereodivergent asymmetric sulfa-Michael additions of α-branched enones using a single chiral organic catalyst.
|Journal of the American Chemical Society 20111109
|Identification of the best-suited leaving group for the diastereoselective synthesis of glycidic amides from stabilised ammonium ylides and aldehydes.
|Organic & biomolecular chemistry 20111021
|Designing the synthesis of catalytically active Ti-β by using various new templates in the presence of fluoride anion.
|Physical chemistry chemical physics : PCCP 20110928
|Theoretical investigation on mechanism of asymmetric Michael addition of malononitrile to chalcones catalyzed by Cinchona alkaloid aluminium(III) complex.
|Organic & biomolecular chemistry 20110921
|Effect of stereogenic centers on the self-sorting, depolymerization, and atropisomerization kinetics of porphyrin-based aggregates.
|Journal of the American Chemical Society 20110810
|Two squalene synthase inhibitors, E5700 and ER-119884, interfere with cellular proliferation and induce ultrastructural and lipid profile alterations in a Candida tropicalis strain resistant to fluconazole, itraconazole, and amphotericin B.
|Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy 20110801
|Intermolecular radical addition to N-acylhydrazones as a stereocontrol strategy for alkaloid synthesis: formal synthesis of quinine.
|Organic & biomolecular chemistry 20110607
|Discovery of novel quaternary ammonium derivatives of (3R)-quinuclidinyl carbamates as potent and long acting muscarinic antagonists.
|Bioorganic & medicinal chemistry letters 20110601
|The hydroxyl functionality and a rigid proximal N are required for forming a novel non-covalent quinine-heme complex.
|Journal of inorganic biochemistry 20110301
|Synthetic arylquinuclidine derivatives exhibit antifungal activity against Candida albicans, Candida tropicalis and Candida parapsilopsis.
|Annals of clinical microbiology and antimicrobials 20110101
|Synthesis and in vitro evaluation of novel nortropane derivatives as potential radiotracers for muscarinic m(2) receptors.
|International journal of molecular imaging 20110101
|Squalene synthase inhibitors: An update on the search for new antihyperlipidemic and antiatherosclerotic agents.
|Current medicinal chemistry 20110101
|Antiproliferative, Ultrastructural, and Physiological Effects of Amiodarone on Promastigote and Amastigote Forms of Leishmania amazonensis.
|Molecular biology international 20110101
|Structural analysis of prolyl oligopeptidases using molecular docking and dynamics: insights into conformational changes and ligand binding.
|PloS one 20110101
|Antiangiogenic properties of substituted (Z)-(±)-2-(N-benzylindol-3-ylmethylene)quinuclidin-3-ol/one analogs and their derivatives.
|Bioorganic & medicinal chemistry letters 20101215
|Surface plasmon resonance biosensor based fragment screening using acetylcholine binding protein identifies ligand efficiency hot spots (LE hot spots) by deconstruction of nicotinic acetylcholine receptor α7 ligands.
|Journal of medicinal chemistry 20101014
|Unexpected enantioseparation of mandelic acids and their derivatives on 1,2,3-triazolo-linked quinine tert-butyl carbamate anion exchange-type chiral stationary phase.
|Journal of separation science 20100901
|3-D-QSAR and docking studies on the neuronal choline transporter.
|Bioorganic & medicinal chemistry letters 20100815
|Multiple species metabolism of PHA-568487, a selective alpha 7 nicotinic acetylcholine receptor agonist.
|Drug metabolism letters 20100801
|Binary complexes of tertiary amines with phenylacetylene. Dispersion wins over electrostatics.
|Physical chemistry chemical physics : PCCP 20100621
|Using the pyridine and quinuclidine scaffolds for superbases: a DFT study.
|The Journal of organic chemistry 20100416
|Enantioselective synthesis of a chiral C(3)-symmetric bridgehead amine.
|Organic letters 20100416
|Chiral recognition in cinchona alkaloid protonated dimers: mass spectrometry and UV photodissociation studies.
|The journal of physical chemistry. A 20100311
|HPLC method for determination of fluorescence derivatives of cortisol, cortisone and their tetrahydro- and allo-tetrahydro-metabolites in biological fluids.
|Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20100201
|SN2' versus SN2 reactivity: control of regioselectivity in conversions of Baylis-Hillman adducts.
|Chemistry (Weinheim an der Bergstrasse, Germany) 20100125
|Cucurbituril host-guest complexes of cholines and phosphonium cholines in aqueous solution.
|Organic & biomolecular chemistry 20100107
|Delineation of downstream signalling components during acrosome reaction mediated by heat solubilized human zona pellucida.
|Reproductive biology and endocrinology : RB&E 20100101
|Generating a generation of proteasome inhibitors: from microbial fermentation to total synthesis of salinosporamide a (marizomib) and other salinosporamides.
|Marine drugs 20100101
|α7 Nicotinic Receptor Agonists: Potential Therapeutic Drugs for Treatment of Cognitive Impairments in Schizophrenia and Alzheimer's Disease.
|The open medicinal chemistry journal 20100101
|Host-guest complexes and pseudorotaxanes of cucurbituril with acetylcholinesterase inhibitors.
|The Journal of organic chemistry 20091106
|Atmospheric heterogeneous stereochemistry.
|Journal of the American Chemical Society 20090930
|Organocatalytic activity of cinchona alkaloids: which nitrogen is more nucleophilic?
|The Journal of organic chemistry 20090918
|Tertiary amine and N-heterocyclic carbene coordinated haloalanes--synthesis, structure, and application.
|Chemistry (Weinheim an der Bergstrasse, Germany) 20090914
|Influence of peripheral groups on the physical and chemical behavior of cinchona alkaloids.
|The journal of physical chemistry. B 20090827
|Stereocontrolled synthesis and pharmacological evaluation of cis-2,6-diphenethyl-1-azabicyclo[2.2.2]octanes as lobelane analogues.
|The Journal of organic chemistry 20090821
|Fluorinated quinine alkaloids: synthesis, X-ray structure analysis and antimalarial parasite chemotherapy.
|Chemistry (Weinheim an der Bergstrasse, Germany) 20090803
|New, improved treatments for Chagas disease: from the R&D pipeline to the patients.
|PLoS neglected tropical diseases 20090701
|Discovery of novel 1-azoniabicyclo[2.2.2]octane muscarinic acetylcholine receptor antagonists.
|Journal of medicinal chemistry 20090423
|Structure and rheology of cationic molecular hydrogels of quinuclidine grafted bile salts. Influence of the ionic strength and counter-ion type.
|The journal of physical chemistry. B 20090409
|1-Pyridine- and 1-quinuclidine-1-boraadamantane as models for derivatives of 1-borabicyclo[2.2.2]octane. Experimental and theoretical evaluation of the B-N fragment as a polar isosteric substitution for the C-C group in liquid crystal compounds.
|The Journal of organic chemistry 20090220
|Fluorescence quenching of CdSe quantum dots by tertiary amines and their surface binding effect.
|Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology 20090101
|Efficient N-arylation/dealkylation of electron deficient heteroaryl chlorides and bicyclic tertiary amines under microwave irradiation.
|Journal of combinatorial chemistry 20090101
|Management of postoperative nausea and vomiting: focus on palonosetron.
|Therapeutics and clinical risk management 20090101
|Sterol Biosynthesis Pathway as Target for Anti-trypanosomatid Drugs.
|Interdisciplinary perspectives on infectious diseases 20090101
|The solubilisation of boar sperm membranes by different detergents - a microscopic, MALDI-TOF MS, (31)P NMR and PAGE study on membrane lysis, extraction efficiency, lipid and protein composition.
|Lipids in health and disease 20090101
|High-frequency Broadband Modulations of Electroencephalographic Spectra.
|Frontiers in human neuroscience 20090101
|Multiple pharmacophores for the selective activation of nicotinic alpha7-type acetylcholine receptors.
|Molecular pharmacology 20081201
|Use of molecular electrostatic potential for quantitative assessment of inductive effect.
|Physical chemistry chemical physics : PCCP 20081121
|Polyepichlorhydrin membranes for alkaline fuel cells: sorption and conduction properties.
|The journal of physical chemistry. B 20081002
|Interaction energies and dynamics of acid-base pairs isolated in cavitands.
|The Journal of organic chemistry 20080905
|The crystal structure of halofantrine-ferriprotoporphyrin IX and the mechanism of action of arylmethanol antimalarials.
|Journal of inorganic biochemistry 20080801
|Application of the PM6 method to modeling the solid state.
|Journal of molecular modeling 20080601
|Acta crystallographica. Section E, Structure reports online 20080501
|Acta crystallographica. Section E, Structure reports online 20080501
|alpha7 nicotinic acetylcholine receptor agonist properties of tilorone and related tricyclic analogues.
|British journal of pharmacology 20080301
|Quinuclidine complex with alpha-cyclodextrin: a diffusion and 13C NMR relaxation study.
|Magnetic resonance in chemistry : MRC 20080301
|Synthetic efforts for stereo structure determination of cytotoxic marine natural product pericosines as metabolites of Periconia sp. from sea hare.
|International journal of molecular sciences 20080301
|1-[(Diethyl-amino-carbon-yl)meth-yl]-2-[hydr-oxy(6-methoxy-quinolin-4-yl)meth-yl]-5-vinyl-1-azoniabicyclo-[2.2.2]octane chloride monohydrate.
|Acta crystallographica. Section E, Structure reports online 20080201
|Huge deuterated effect on permittivity in a metal-organic framework.
|Chemistry (Weinheim an der Bergstrasse, Germany) 20080101
|Mixed-ligand metal-organic frameworks with large pores: gas sorption properties and single-crystal-to-single-crystal transformation on guest exchange.
|Chemistry (Weinheim an der Bergstrasse, Germany) 20080101
|Synthesis and characterization of new nitrogen-donor-stabilized N-silylphosphoranimine cations.
|Inorganic chemistry 20071112
|Adducts of rhodium(II) tetraacetate with some nitrogenous organic ligands: application of natural abundance 15N and 13C CPMAS NMR spectroscopy.
|Solid state nuclear magnetic resonance 20071001
|Role of guiding groups in cinchona-modified platinum for controlling the sense of enantiodifferentiation in the hydrogenation of ketones.
|Journal of the American Chemical Society 20070829
|Metabolism, pharmacokinetics, and excretion of a nonpeptidic substance P receptor antagonist, ezlopitant, in normal healthy male volunteers: characterization of polar metabolites by chemical derivatization with dansyl chloride.
|Drug metabolism and disposition: the biological fate of chemicals 20070701
|Molecular structures of free quinuclidine and its adducts with metal trihydrides, MH3 (M=B, Al or Ga), studied by gas-phase electron diffraction, X-ray diffraction and quantum chemical calculations.
|Dalton transactions (Cambridge, England : 2003) 20070507
|Quinuclidines as selective agonists for alpha-7 nicotinic acetylcholine receptors.
|Bioorganic & medicinal chemistry letters 20070315
|Investigation of the stability of the M-H-B bond in borane sigma complexes [M(CO)5(eta1-BH2R.L)] and [CpMn(CO)2(eta1-BH2R.L)] (M=Cr, W; L=tertiary amine or phosphine): substituent and Lewis base effects.
|Chemistry (Weinheim an der Bergstrasse, Germany) 20070101
|Effectiveness of low-dose doxycycline (LDD) on clinical symptoms of Sjögren's syndrome: a randomized, double-blind, placebo controlled cross-over study.
|Journal of negative results in biomedicine 20070101
|The nature of the chemical bond in linear three-body systems: from i3- to mixed chalcogen/halogen and trichalcogen moieties.
|Bioinorganic chemistry and applications 20070101
|A synthetic mimic of protein inner space: buried polar interactions in a deep water-soluble host.
|Journal of the American Chemical Society 20061206
|Synthetic studies on quinine: quinuclidine construction via a ketone enolate regio- and diastereoselective Pd-mediated allylic alkylation.
|Organic letters 20060831
|Method for enantiomeric purity of a quinuclidine candidate drug by capillary electrophoresis.
|Journal of separation science 20060801
|RP-HPLC method with fluorescence detection for determination of small quantities of triamcinolone in plasma in presence of endogenous steroids after derivatization with 9-anthroyl nitrile; pharmacokinetic studies.
|Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20060724
|Antiproliferative activities of two novel quinuclidine inhibitors against Toxoplasma gondii tachyzoites in vitro.
|The Journal of antimicrobial chemotherapy 20060701
|A generalized two-point H-bonding model for catalytic stereoselective hydrogenation of activated ketones on chirally modified platinum.
|Journal of the American Chemical Society 20060614
|Pyridinium, imidazolium and quinuclidinium compounds: toxicity and antidotal effects against the nerve agents Tabun and Soman.
|Arhiv za higijenu rada i toksikologiju 20060601
|Perturbation of adsorbed CO by amine derivatives coadsorbed on the gamma-Al2O3 surface: FTIR and first principles studies.
|The journal of physical chemistry. B 20060316
|Potent anti-muscarinic activity in a novel series of quinuclidine derivatives.
|Bioorganic & medicinal chemistry letters 20060115
|m-Calpain is required for preimplantation embryonic development in mice.
|BMC developmental biology 20060101
|Zona pellucida from fertilised human oocytes induces a voltage-dependent calcium influx and the acrosome reaction in spermatozoa, but cannot be penetrated by sperm.
|BMC developmental biology 20060101
|Structure and reactivity of trans-bis[2-(2-chloroethyl)pyridine]palladium chloride (1). A study on the elimination reaction of 1 and 2-(2-chloroethyl)pyridine induced by quinuclidine in acetonitrile.
|The Journal of organic chemistry 20051223
|Rate-limiting proton-transfer in the sigma-adduct forming reactions of 1,3,5-trinitrobenzene and 4-nitrobenzofuroxan with substituted anilines in dimethyl sulfoxide.
|Organic & biomolecular chemistry 20051107
|High affinity ligands for the alpha7 nicotinic receptor that show no cross-reactivity with the 5-HT3 receptor.
|Bioorganic & medicinal chemistry letters 20051101
|Synthesis and antimuscarinic properties of quinuclidin-3-yl 1,2,3,4-tetrahydroisoquinoline-2-carboxylate derivatives as novel muscarinic receptor antagonists.
|Journal of medicinal chemistry 20051020
|A deep cavitand provides a structured environment for the Menschutkin reaction.
|Journal of the American Chemical Society 20050817
|Mono- and digallane complexes of a tridentate amido-diamine ligand.
|Chemical communications (Cambridge, England) 20050721
|Competition at chiral metal surfaces: fundamental aspects of the inversion of enantioselectivity in hydrogenations on platinum.
|Journal of the American Chemical Society 20050615
|Synthesis, X-ray crystal structures, and gas sorption properties of pillared square grid nets based on paddle-wheel motifs: implications for hydrogen storage in porous materials.
|Chemistry (Weinheim an der Bergstrasse, Germany) 20050606
|Orientational isomers of alpha-cyclodextrin semi-rotaxanes with asymmetric dicationic threads.
|Organic & biomolecular chemistry 20050421
|3-Aminomethyl derivatives of 4,11-dihydroxynaphtho[2,3-f]indole-5,10-dione for circumvention of anticancer drug resistance.
|Bioorganic & medicinal chemistry 20050315
|Homotryptamines as potent and selective serotonin reuptake inhibitors (SSRIs).
|Bioorganic & medicinal chemistry letters 20050315
|Synthesis and photophysical properties of models for twisted PRODAN and dimethylaminonaphthonitrile.
|The journal of physical chemistry. A 20050224
|Structure-property relationship in py-hexahydrocinchonidine diastereomers: ab initio and NMR study.
|The journal of physical chemistry. A 20050210
|Cobalt complexes with cinchonidine and quinidine: effect of C8/C9 stereochemistry and 6'-substitution on intermolecular interactions.
|Synthesis and biodistribution of radiolabeled alpha 7 nicotinic acetylcholine receptor ligands.
|Journal of nuclear medicine : official publication, Society of Nuclear Medicine 20050201
|Rigidified tripodal chiral ligands in the asymmetric recognition of amino compounds.
|Synthesis and biological evaluation of quinuclidine derivatives incorporating phenothiazine moieties as squalene synthase inhibitors.
|Chemical & pharmaceutical bulletin 20041001
|Effect of humanin analogues on experimentally induced impairment of spatial memory in rats.
|Journal of peptide science : an official publication of the European Peptide Society 20041001
|Acrylamide in the Baylis-Hillman reaction: expanded reaction scope and the unexpected superiority of DABCO over more basic tertiary amine catalysts.
|The Journal of organic chemistry 20040917
|Synthesis and evaluation of phenylcarbamate derivatives as ligands for nicotinic acetylcholine receptors.
|Bioorganic & medicinal chemistry 20040915
|Me2AlCH2PMe2: a new, bifunctional cocatalyst for the Ni(II)-catalyzed oligomerization of PhSiH3.
|Journal of the American Chemical Society 20040721
|Reduction reactions of a 1,3,5-triphosphabenzene.
|Dalton transactions (Cambridge, England : 2003) 20040707
|Direct STM investigation of cinchona alkaloid adsorption on Cu(III).
|Langmuir : the ACS journal of surfaces and colloids 20040413
|Mechanisms of acid-base catalysis of beta-elimination reactions in systems activated by a pyridine ring.
|The Journal of organic chemistry 20040402
|Crystal and molecular structures of new enantiopure quinuclidines.
|Generation and coupling of [Mn(dmpe)2(C triple bond CR)(C triple bond C)]* radicals producing redox-active C4-bridged rigid-rod complexes.
|Chemistry (Weinheim an der Bergstrasse, Germany) 20031215
|Solvent-stabilized molecular capsules.
|The Journal of organic chemistry 20030822
|Cinchona alkaloid derived ligands in catalytic asymmetric transfer hydrogenation.
|Organic & biomolecular chemistry 20030721
|Sensitive determination of alkoxyethanols by pre-column derivatization with 1-anthroylnitrile and reversed-phase high-performance liquid chromatography.
|Journal of chromatography. A 20030711
|Age-related decreases in the response of aquaporin-5 to acetylcholine in rat parotid glands.
|Journal of dental research 20030601
|Syntheses and biological evaluation of novel quinuclidine derivatives as squalene synthase inhibitors.
|Bioorganic & medicinal chemistry 20030529
|3D QSAR analyses-guided rational design of novel ligands for the (alpha4)2(beta2)3 nicotinic acetylcholine receptor.
|Journal of medicinal chemistry 20030522
|Correlation between pK(a) and reactivity of quinuclidine-based catalysts in the Baylis-Hillman reaction: discovery of quinuclidine as optimum catalyst leading to substantial enhancement of scope.
|The Journal of organic chemistry 20030207
|Daphcalycine, a novel heptacycle fused ring system alkaloid from Daphniphyllum calycinum.
|The Journal of organic chemistry 20030124
|The relationship of physico-chemical properties and structure to the differential antiplasmodial activity of the cinchona alkaloids.
|Malaria journal 20030101
|Adsorption mode of cinchonidine on Cu(111) surface.
|Journal of the American Chemical Society 20021204
|Photoelectron spectra and electronic structure of some diastereomeric quinuclidine derivatives.
|Chemphyschem : a European journal of chemical physics and physical chemistry 20021115
|The inhibitory effects of tramadol on muscarinic receptor-induced responses in Xenopus oocytes expressing cloned M(3) receptors.
|Anesthesia and analgesia 20021101
|[Cevimeline hydrochloride hydrate (Saligren capsule 30 mg): a review of its pharmacological profiles and clinical potential in xerostomia].
|Nihon yakurigaku zasshi. Folia pharmacologica Japonica 20021001
|Metal-switching and self-inclusion of functional cavitands.
|Journal of the American Chemical Society 20020904
|Novel potent 5-HT(3) receptor ligands based on the pyrrolidone structure. Effects of the quaternization of the basic nitrogen on the interaction with 5-HT(3) receptor.
|Bioorganic & medicinal chemistry 20020801
|The Interactions of the 5-HT(3) receptor with arylpiperazine, tropane, and quinuclidine ligands.
|Current topics in medicinal chemistry 20020601
|Aromatic 4-tetrahydropyranyl and 4-quinuclidinyl cations. Linking Prins with Cope and Grob.
|Journal of the American Chemical Society 20020508
|Formation and stability of enolates of acetamide and acetate anion: an Eigen plot for proton transfer at alpha-carbonyl carbon.
|Journal of the American Chemical Society 20020327
|Practical Os/Cu-cocatalyzed air oxidation of allyl and benzyl alcohols at room temperature and atmospheric pressure.
|Organic letters 20020321
|Novel potent 5-HT(3) receptor ligands based on the pyrrolidone structure: synthesis, biological evaluation, and computational rationalization of the ligand-receptor interaction modalities.
|Bioorganic & medicinal chemistry 20020301
|Metal ligation regulates conformational equilibria and binding properties of cavitands.
|Organic letters 20020207
|Quinuclidinone O-Alkynyloximes with muscarinic agonist activity.
|Bioorganic & medicinal chemistry 20020101
|New crystalline complex of quinine and quinidine.
|Cinchoninium L-tartrate tetrahydrate.
|Acta crystallographica. Section C, Crystal structure communications 20011201
|A self-folding metallocavitand.
|Journal of the American Chemical Society 20011017
|Oxidation of NADH by chloramines and chloramides and its activation by iodide and by tertiary amines.
|Archives of biochemistry and biophysics 20010915
|Design and pharmacology of quinuclidine derivatives as M2-selective muscarinic receptor ligands.
|Bioorganic & medicinal chemistry letters 20010507
|Syntheses of the first amine-dicarboxyboranes and their bis(methylester) and bis(N-ethylamide) derivatives.
|Inorganic chemistry 20010409
|The 5-HT3 antagonist tropisetron (ICS 205-930) is a potent and selective alpha7 nicotinic receptor partial agonist.
|Bioorganic & medicinal chemistry letters 20010212
|Gallane complexes with amido-amine ligands.
|Inorganic chemistry 20010115
|SPET imaging of central muscarinic acetylcholine receptors with iodine-123 labelled E-IQNP and Z-IQNP.
|European journal of nuclear medicine 20010101
|Crystal and molecular structure of a new cobalt complex of quinine.